Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w1a_vs_wt_vs_wt.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp_repos |
| Phenotype | w1a_vs_wt.cls#ago1w1a_versus_ago1gfp_repos |
| Upregulated in class | ago1gfp |
| GeneSet | KEGG_RENIN_ANGIOTENSIN_SYSTEM |
| Enrichment Score (ES) | -0.40403506 |
| Normalized Enrichment Score (NES) | -1.0898132 |
| Nominal p-value | 0.3041096 |
| FDR q-value | 0.6916743 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | LNPEP | NA | LNPEP Entrez, Source | leucyl/cystinyl aminopeptidase | 982 | 2.355 | 0.1049 | No |
| 2 | THOP1 | NA | THOP1 Entrez, Source | thimet oligopeptidase 1 | 3275 | 1.067 | 0.0496 | No |
| 3 | CTSA | NA | 3702 | 0.940 | 0.0896 | No | ||
| 4 | ACE2 | NA | ACE2 Entrez, Source | angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 | 3815 | 0.913 | 0.1452 | No |
| 5 | REN | NA | REN Entrez, Source | renin | 6052 | 0.459 | 0.0518 | No |
| 6 | NLN | NA | NLN Entrez, Source | neurolysin (metallopeptidase M3 family) | 7581 | 0.245 | -0.0166 | No |
| 7 | MME | NA | MME Entrez, Source | membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase) | 8894 | 0.110 | -0.0822 | No |
| 8 | AGTR1 | NA | AGTR1 Entrez, Source | angiotensin II receptor, type 1 | 11053 | -0.086 | -0.1965 | No |
| 9 | AGTR2 | NA | AGTR2 Entrez, Source | angiotensin II receptor, type 2 | 11762 | -0.163 | -0.2248 | No |
| 10 | MAS1 | NA | MAS1 Entrez, Source | MAS1 oncogene | 12732 | -0.281 | -0.2598 | No |
| 11 | CPA3 | NA | CPA3 Entrez, Source | carboxypeptidase A3 (mast cell) | 15325 | -0.812 | -0.3491 | Yes |
| 12 | CTSG | NA | CTSG Entrez, Source | cathepsin G | 15560 | -0.884 | -0.3022 | Yes |
| 13 | ENPEP | NA | ENPEP Entrez, Source | glutamyl aminopeptidase (aminopeptidase A) | 15740 | -0.945 | -0.2481 | Yes |
| 14 | AGT | NA | AGT Entrez, Source | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 16745 | -1.468 | -0.2046 | Yes |
| 15 | ANPEP | NA | ANPEP Entrez, Source | alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150) | 16845 | -1.542 | -0.1056 | Yes |
| 16 | ACE | NA | ACE Entrez, Source | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 17524 | -2.491 | 0.0254 | Yes |
