Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w1a_vs_wt_vs_wt.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp_repos |
| Phenotype | w1a_vs_wt.cls#ago1w1a_versus_ago1gfp_repos |
| Upregulated in class | ago1gfp |
| GeneSet | KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION |
| Enrichment Score (ES) | -0.3410852 |
| Normalized Enrichment Score (NES) | -1.293775 |
| Nominal p-value | 0.025 |
| FDR q-value | 0.43344682 |
| FWER p-Value | 0.982 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PIK3CA | NA | PIK3CA Entrez, Source | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 749 | 2.649 | 0.0016 | No |
| 2 | PIK3R3 | NA | PIK3R3 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma) | 1410 | 1.946 | -0.0033 | No |
| 3 | MAD2L2 | NA | MAD2L2 Entrez, Source | MAD2 mitotic arrest deficient-like 2 (yeast) | 2042 | 1.533 | -0.0134 | No |
| 4 | PIK3R1 | NA | PIK3R1 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha) | 2108 | 1.493 | 0.0075 | No |
| 5 | CDC25B | NA | CDC25B Entrez, Source | cell division cycle 25B | 2124 | 1.483 | 0.0310 | No |
| 6 | PGR | NA | PGR Entrez, Source | progesterone receptor | 2447 | 1.348 | 0.0351 | No |
| 7 | GNAI1 | NA | GNAI1 Entrez, Source | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2654 | 1.262 | 0.0443 | No |
| 8 | PDE3A | NA | PDE3A Entrez, Source | phosphodiesterase 3A, cGMP-inhibited | 3564 | 0.980 | 0.0096 | No |
| 9 | BUB1 | NA | BUB1 Entrez, Source | BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast) | 3716 | 0.937 | 0.0165 | No |
| 10 | ANAPC4 | NA | ANAPC4 Entrez, Source | anaphase promoting complex subunit 4 | 4268 | 0.800 | -0.0011 | No |
| 11 | CDC25C | NA | CDC25C Entrez, Source | cell division cycle 25C | 4298 | 0.794 | 0.0103 | No |
| 12 | CDC27 | NA | CDC27 Entrez, Source | cell division cycle 27 | 4376 | 0.776 | 0.0187 | No |
| 13 | RPS6KA1 | NA | RPS6KA1 Entrez, Source | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 4439 | 0.764 | 0.0278 | No |
| 14 | ADCY9 | NA | ADCY9 Entrez, Source | adenylate cyclase 9 | 4606 | 0.724 | 0.0304 | No |
| 15 | MAPK14 | NA | MAPK14 Entrez, Source | mitogen-activated protein kinase 14 | 4701 | 0.703 | 0.0367 | No |
| 16 | CDC23 | NA | CDC23 Entrez, Source | CDC23 (cell division cycle 23, yeast, homolog) | 5411 | 0.565 | 0.0064 | No |
| 17 | MAPK9 | NA | MAPK9 Entrez, Source | mitogen-activated protein kinase 9 | 6268 | 0.418 | -0.0346 | No |
| 18 | AKT2 | NA | AKT2 Entrez, Source | v-akt murine thymoma viral oncogene homolog 2 | 6498 | 0.385 | -0.0411 | No |
| 19 | HSP90AB1 | NA | HSP90AB1 Entrez, Source | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 6586 | 0.373 | -0.0398 | No |
| 20 | PRKX | NA | PRKX Entrez, Source | protein kinase, X-linked | 6692 | 0.358 | -0.0398 | No |
| 21 | CCNB3 | NA | CCNB3 Entrez, Source | cyclin B3 | 6817 | 0.341 | -0.0411 | No |
| 22 | GNAI3 | NA | GNAI3 Entrez, Source | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 6912 | 0.327 | -0.0410 | No |
| 23 | CPEB1 | NA | CPEB1 Entrez, Source | cytoplasmic polyadenylation element binding protein 1 | 7084 | 0.305 | -0.0456 | No |
| 24 | IGF1 | NA | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 7209 | 0.286 | -0.0478 | No |
| 25 | KRAS | NA | KRAS Entrez, Source | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 7514 | 0.251 | -0.0607 | No |
| 26 | PIK3CB | NA | PIK3CB Entrez, Source | phosphoinositide-3-kinase, catalytic, beta polypeptide | 7635 | 0.240 | -0.0634 | No |
| 27 | ADCY4 | NA | ADCY4 Entrez, Source | adenylate cyclase 4 | 7650 | 0.238 | -0.0603 | No |
| 28 | ADCY6 | NA | ADCY6 Entrez, Source | adenylate cyclase 6 | 7968 | 0.207 | -0.0746 | No |
| 29 | ADCY1 | NA | ADCY1 Entrez, Source | adenylate cyclase 1 (brain) | 8159 | 0.181 | -0.0823 | No |
| 30 | CCNA1 | NA | CCNA1 Entrez, Source | cyclin A1 | 8310 | 0.168 | -0.0879 | No |
| 31 | ARAF | NA | ARAF Entrez, Source | v-raf murine sarcoma 3611 viral oncogene homolog | 8641 | 0.139 | -0.1040 | No |
| 32 | ADCY2 | NA | ADCY2 Entrez, Source | adenylate cyclase 2 (brain) | 8813 | 0.120 | -0.1116 | No |
| 33 | MAPK10 | NA | MAPK10 Entrez, Source | mitogen-activated protein kinase 10 | 9003 | 0.098 | -0.1206 | No |
| 34 | MAPK8 | NA | MAPK8 Entrez, Source | mitogen-activated protein kinase 8 | 9814 | 0.009 | -0.1657 | No |
| 35 | PIK3R5 | NA | PIK3R5 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 5, p101 | 9845 | 0.004 | -0.1673 | No |
| 36 | ANAPC2 | NA | ANAPC2 Entrez, Source | anaphase promoting complex subunit 2 | 10208 | -0.006 | -0.1874 | No |
| 37 | PRKACA | NA | PRKACA Entrez, Source | protein kinase, cAMP-dependent, catalytic, alpha | 10652 | -0.045 | -0.2114 | No |
| 38 | ADCY7 | NA | ADCY7 Entrez, Source | adenylate cyclase 7 | 10682 | -0.049 | -0.2122 | No |
| 39 | PRKACG | NA | PRKACG Entrez, Source | protein kinase, cAMP-dependent, catalytic, gamma | 11122 | -0.095 | -0.2352 | No |
| 40 | ANAPC11 | NA | ANAPC11 Entrez, Source | APC11 anaphase promoting complex subunit 11 homolog (yeast) | 11653 | -0.149 | -0.2624 | No |
| 41 | SPDYA | NA | SPDYA Entrez, Source | speedy homolog A (Drosophila) | 11718 | -0.157 | -0.2634 | No |
| 42 | MAPK1 | NA | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 12360 | -0.233 | -0.2954 | No |
| 43 | PIK3R2 | NA | PIK3R2 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta) | 12508 | -0.252 | -0.2994 | No |
| 44 | PIK3CD | NA | PIK3CD Entrez, Source | phosphoinositide-3-kinase, catalytic, delta polypeptide | 12596 | -0.262 | -0.3000 | No |
| 45 | MAPK13 | NA | MAPK13 Entrez, Source | mitogen-activated protein kinase 13 | 12817 | -0.293 | -0.3075 | No |
| 46 | ANAPC10 | NA | ANAPC10 Entrez, Source | anaphase promoting complex subunit 10 | 12883 | -0.299 | -0.3062 | No |
| 47 | ANAPC1 | NA | ANAPC1 Entrez, Source | anaphase promoting complex subunit 1 | 13038 | -0.324 | -0.3095 | No |
| 48 | ADCY5 | NA | ADCY5 Entrez, Source | adenylate cyclase 5 | 13236 | -0.354 | -0.3147 | No |
| 49 | FZR1 | NA | FZR1 Entrez, Source | fizzy/cell division cycle 20 related 1 (Drosophila) | 13353 | -0.375 | -0.3150 | No |
| 50 | CCNB1 | NA | CCNB1 Entrez, Source | cyclin B1 | 13372 | -0.378 | -0.3098 | No |
| 51 | RAF1 | NA | RAF1 Entrez, Source | v-raf-1 murine leukemia viral oncogene homolog 1 | 13760 | -0.446 | -0.3241 | No |
| 52 | PLK1 | NA | PLK1 Entrez, Source | polo-like kinase 1 (Drosophila) | 13882 | -0.468 | -0.3232 | No |
| 53 | PKMYT1 | NA | PKMYT1 Entrez, Source | protein kinase, membrane associated tyrosine/threonine 1 | 13961 | -0.483 | -0.3196 | No |
| 54 | ADCY8 | NA | ADCY8 Entrez, Source | adenylate cyclase 8 (brain) | 14346 | -0.562 | -0.3319 | Yes |
| 55 | ANAPC7 | NA | ANAPC7 Entrez, Source | anaphase promoting complex subunit 7 | 14348 | -0.562 | -0.3227 | Yes |
| 56 | CDC16 | NA | CDC16 Entrez, Source | CDC16 cell division cycle 16 homolog (S. cerevisiae) | 14441 | -0.581 | -0.3183 | Yes |
| 57 | PDE3B | NA | PDE3B Entrez, Source | phosphodiesterase 3B, cGMP-inhibited | 14517 | -0.596 | -0.3127 | Yes |
| 58 | RPS6KA3 | NA | RPS6KA3 Entrez, Source | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 14560 | -0.608 | -0.3051 | Yes |
| 59 | CCNA2 | NA | CCNA2 Entrez, Source | cyclin A2 | 14721 | -0.650 | -0.3033 | Yes |
| 60 | CDC26 | NA | CDC26 Entrez, Source | cell division cycle 26 | 14880 | -0.690 | -0.3008 | Yes |
| 61 | AKT3 | NA | AKT3 Entrez, Source | v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) | 14929 | -0.703 | -0.2920 | Yes |
| 62 | RPS6KA6 | NA | RPS6KA6 Entrez, Source | ribosomal protein S6 kinase, 90kDa, polypeptide 6 | 15030 | -0.729 | -0.2856 | Yes |
| 63 | BRAF | NA | BRAF Entrez, Source | v-raf murine sarcoma viral oncogene homolog B1 | 15145 | -0.758 | -0.2795 | Yes |
| 64 | MAD2L1 | NA | MAD2L1 Entrez, Source | MAD2 mitotic arrest deficient-like 1 (yeast) | 15220 | -0.779 | -0.2709 | Yes |
| 65 | HSP90AA1 | NA | HSP90AA1 Entrez, Source | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 15288 | -0.799 | -0.2615 | Yes |
| 66 | AKT1 | NA | AKT1 Entrez, Source | v-akt murine thymoma viral oncogene homolog 1 | 15339 | -0.816 | -0.2509 | Yes |
| 67 | PRKACB | NA | PRKACB Entrez, Source | protein kinase, cAMP-dependent, catalytic, beta | 15440 | -0.844 | -0.2427 | Yes |
| 68 | CDK2 | NA | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 15469 | -0.852 | -0.2302 | Yes |
| 69 | CDC25A | NA | CDC25A Entrez, Source | cell division cycle 25A | 15476 | -0.855 | -0.2165 | Yes |
| 70 | ANAPC13 | NA | ANAPC13 Entrez, Source | anaphase promoting complex subunit 13 | 15614 | -0.899 | -0.2094 | Yes |
| 71 | GNAI2 | NA | GNAI2 Entrez, Source | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 15665 | -0.914 | -0.1972 | Yes |
| 72 | CDK1 | NA | 16088 | -1.080 | -0.2031 | Yes | ||
| 73 | IGF1R | NA | IGF1R Entrez, Source | insulin-like growth factor 1 receptor | 16126 | -1.101 | -0.1871 | Yes |
| 74 | ADCY3 | NA | ADCY3 Entrez, Source | adenylate cyclase 3 | 16173 | -1.126 | -0.1712 | Yes |
| 75 | MAPK12 | NA | MAPK12 Entrez, Source | mitogen-activated protein kinase 12 | 16388 | -1.240 | -0.1628 | Yes |
| 76 | MAPK3 | NA | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 16431 | -1.263 | -0.1444 | Yes |
| 77 | MAP2K1 | NA | MAP2K1 Entrez, Source | mitogen-activated protein kinase kinase 1 | 16504 | -1.300 | -0.1271 | Yes |
| 78 | ANAPC5 | NA | ANAPC5 Entrez, Source | anaphase promoting complex subunit 5 | 16920 | -1.607 | -0.1239 | Yes |
| 79 | CCNB2 | NA | CCNB2 Entrez, Source | cyclin B2 | 16921 | -1.610 | -0.0975 | Yes |
| 80 | MAPK11 | NA | MAPK11 Entrez, Source | mitogen-activated protein kinase 11 | 17421 | -2.271 | -0.0881 | Yes |
| 81 | RPS6KA2 | NA | RPS6KA2 Entrez, Source | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 17479 | -2.377 | -0.0522 | Yes |
| 82 | PIK3CG | NA | PIK3CG Entrez, Source | phosphoinositide-3-kinase, catalytic, gamma polypeptide | 17957 | -4.885 | 0.0013 | Yes |
