Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w1a_vs_wt_vs_wt.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp_repos |
| Phenotype | w1a_vs_wt.cls#ago1w1a_versus_ago1gfp_repos |
| Upregulated in class | ago1w1a |
| GeneSet | KEGG_INTESTINAL_IMMUNE_NETWORK_FOR_IGA_PRODUCTION |
| Enrichment Score (ES) | 0.6376045 |
| Normalized Enrichment Score (NES) | 1.8965188 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.007710275 |
| FWER p-Value | 0.008 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | ICOSLG | NA | ICOSLG Entrez, Source | inducible T-cell co-stimulator ligand | 81 | 4.595 | 0.0727 | Yes |
| 2 | HLA-DRA | NA | HLA-DRA Entrez, Source | major histocompatibility complex, class II, DR alpha | 83 | 4.582 | 0.1497 | Yes |
| 3 | HLA-DRB1 | NA | HLA-DRB1 Entrez, Source | major histocompatibility complex, class II, DR beta 1 | 235 | 3.969 | 0.2079 | Yes |
| 4 | HLA-DPA1 | NA | HLA-DPA1 Entrez, Source | major histocompatibility complex, class II, DP alpha 1 | 345 | 3.598 | 0.2623 | Yes |
| 5 | HLA-DMA | NA | HLA-DMA Entrez, Source | major histocompatibility complex, class II, DM alpha | 556 | 3.030 | 0.3015 | Yes |
| 6 | HLA-DRB5 | NA | HLA-DRB5 Entrez, Source | major histocompatibility complex, class II, DR beta 5 | 611 | 2.898 | 0.3472 | Yes |
| 7 | IL6 | NA | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 690 | 2.778 | 0.3895 | Yes |
| 8 | CCL28 | NA | CCL28 Entrez, Source | chemokine (C-C motif) ligand 28 | 891 | 2.470 | 0.4199 | Yes |
| 9 | TNFSF13B | NA | TNFSF13B Entrez, Source | tumor necrosis factor (ligand) superfamily, member 13b | 893 | 2.462 | 0.4612 | Yes |
| 10 | HLA-DRB3 | NA | HLA-DRB3 Entrez, Source | major histocompatibility complex, class II, DR beta 3 | 916 | 2.438 | 0.5010 | Yes |
| 11 | HLA-DMB | NA | HLA-DMB Entrez, Source | major histocompatibility complex, class II, DM beta | 1107 | 2.215 | 0.5276 | Yes |
| 12 | HLA-DRB4 | NA | HLA-DRB4 Entrez, Source | major histocompatibility complex, class II, DR beta 4 | 1321 | 2.023 | 0.5497 | Yes |
| 13 | HLA-DOB | NA | HLA-DOB Entrez, Source | major histocompatibility complex, class II, DO beta | 1477 | 1.892 | 0.5729 | Yes |
| 14 | CXCR4 | NA | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 1561 | 1.836 | 0.5991 | Yes |
| 15 | MAP3K14 | NA | MAP3K14 Entrez, Source | mitogen-activated protein kinase kinase kinase 14 | 1914 | 1.605 | 0.6064 | Yes |
| 16 | ITGB7 | NA | ITGB7 Entrez, Source | integrin, beta 7 | 2002 | 1.552 | 0.6277 | Yes |
| 17 | PIGR | NA | PIGR Entrez, Source | polymeric immunoglobulin receptor | 2255 | 1.427 | 0.6376 | Yes |
| 18 | LTBR | NA | LTBR Entrez, Source | lymphotoxin beta receptor (TNFR superfamily, member 3) | 4199 | 0.816 | 0.5430 | No |
| 19 | ITGA4 | NA | ITGA4 Entrez, Source | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | 4245 | 0.805 | 0.5540 | No |
| 20 | TNFRSF17 | NA | TNFRSF17 Entrez, Source | tumor necrosis factor receptor superfamily, member 17 | 4724 | 0.699 | 0.5391 | No |
| 21 | HLA-DPB1 | NA | HLA-DPB1 Entrez, Source | major histocompatibility complex, class II, DP beta 1 | 5159 | 0.612 | 0.5252 | No |
| 22 | IL15RA | NA | IL15RA Entrez, Source | interleukin 15 receptor, alpha | 5382 | 0.570 | 0.5224 | No |
| 23 | CD80 | NA | CD80 Entrez, Source | CD80 molecule | 6065 | 0.457 | 0.4920 | No |
| 24 | CCR9 | NA | CCR9 Entrez, Source | chemokine (C-C motif) receptor 9 | 6606 | 0.370 | 0.4681 | No |
| 25 | TGFB1 | NA | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 6816 | 0.341 | 0.4622 | No |
| 26 | HLA-DQB1 | NA | HLA-DQB1 Entrez, Source | major histocompatibility complex, class II, DQ beta 1 | 7133 | 0.297 | 0.4496 | No |
| 27 | CD40LG | NA | CD40LG Entrez, Source | CD40 ligand (TNF superfamily, member 5, hyper-IgM syndrome) | 7609 | 0.242 | 0.4271 | No |
| 28 | HLA-DQA1 | NA | HLA-DQA1 Entrez, Source | major histocompatibility complex, class II, DQ alpha 1 | 7724 | 0.232 | 0.4247 | No |
| 29 | IL2 | NA | IL2 Entrez, Source | interleukin 2 | 8119 | 0.187 | 0.4058 | No |
| 30 | HLA-DOA | NA | HLA-DOA Entrez, Source | major histocompatibility complex, class II, DO alpha | 8378 | 0.164 | 0.3942 | No |
| 31 | ICOS | NA | ICOS Entrez, Source | inducible T-cell co-stimulator | 9281 | 0.073 | 0.3451 | No |
| 32 | CXCL12 | NA | CXCL12 Entrez, Source | chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) | 9424 | 0.058 | 0.3382 | No |
| 33 | IL10 | NA | IL10 Entrez, Source | interleukin 10 | 9803 | 0.010 | 0.3173 | No |
| 34 | IL4 | NA | IL4 Entrez, Source | interleukin 4 | 9924 | 0.000 | 0.3106 | No |
| 35 | CCL27 | NA | CCL27 Entrez, Source | chemokine (C-C motif) ligand 27 | 10532 | -0.036 | 0.2774 | No |
| 36 | HLA-DQA2 | NA | HLA-DQA2 Entrez, Source | major histocompatibility complex, class II, DQ alpha 2 | 10636 | -0.045 | 0.2724 | No |
| 37 | MADCAM1 | NA | MADCAM1 Entrez, Source | mucosal vascular addressin cell adhesion molecule 1 | 11063 | -0.087 | 0.2501 | No |
| 38 | CD86 | NA | CD86 Entrez, Source | CD86 molecule | 11217 | -0.106 | 0.2433 | No |
| 39 | CCL25 | NA | CCL25 Entrez, Source | chemokine (C-C motif) ligand 25 | 11603 | -0.144 | 0.2243 | No |
| 40 | TNFSF13 | NA | TNFSF13 Entrez, Source | tumor necrosis factor (ligand) superfamily, member 13 | 12117 | -0.203 | 0.1991 | No |
| 41 | IL15 | NA | IL15 Entrez, Source | interleukin 15 | 12477 | -0.247 | 0.1832 | No |
| 42 | TNFRSF13B | NA | TNFRSF13B Entrez, Source | tumor necrosis factor receptor superfamily, member 13B | 12535 | -0.256 | 0.1843 | No |
| 43 | AICDA | NA | AICDA Entrez, Source | activation-induced cytidine deaminase | 14034 | -0.496 | 0.1091 | No |
| 44 | TNFRSF13C | NA | TNFRSF13C Entrez, Source | tumor necrosis factor receptor superfamily, member 13C | 15266 | -0.793 | 0.0538 | No |
| 45 | CD28 | NA | CD28 Entrez, Source | CD28 molecule | 16374 | -1.233 | 0.0128 | No |
| 46 | CCR10 | NA | CCR10 Entrez, Source | chemokine (C-C motif) receptor 10 | 16763 | -1.478 | 0.0160 | No |
| 47 | CD40 | NA | CD40 Entrez, Source | CD40 molecule, TNF receptor superfamily member 5 | 17681 | -3.081 | 0.0167 | No |
