Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w1a_vs_wt_vs_wt.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp_repos |
| Phenotype | w1a_vs_wt.cls#ago1w1a_versus_ago1gfp_repos |
| Upregulated in class | ago1gfp |
| GeneSet | KEGG_GLYOXYLATE_AND_DICARBOXYLATE_METABOLISM |
| Enrichment Score (ES) | -0.65064377 |
| Normalized Enrichment Score (NES) | -1.6877313 |
| Nominal p-value | 0.0028735632 |
| FDR q-value | 0.11032388 |
| FWER p-Value | 0.198 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | MTHFD2L | NA | MTHFD2L Entrez, Source | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | 1385 | 1.967 | 0.0299 | No |
| 2 | ACO2 | NA | ACO2 Entrez, Source | aconitase 2, mitochondrial | 6531 | 0.381 | -0.2358 | No |
| 3 | HAO2 | NA | HAO2 Entrez, Source | hydroxyacid oxidase 2 (long chain) | 6675 | 0.360 | -0.2242 | No |
| 4 | CS | NA | CS Entrez, Source | citrate synthase | 6743 | 0.349 | -0.2089 | No |
| 5 | MDH2 | NA | MDH2 Entrez, Source | malate dehydrogenase 2, NAD (mitochondrial) | 9270 | 0.074 | -0.3455 | No |
| 6 | AFMID | NA | AFMID Entrez, Source | arylformamidase | 9653 | 0.032 | -0.3650 | No |
| 7 | GRHPR | NA | GRHPR Entrez, Source | glyoxylate reductase/hydroxypyruvate reductase | 11161 | -0.100 | -0.4434 | No |
| 8 | MTHFD1 | NA | MTHFD1 Entrez, Source | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 14090 | -0.507 | -0.5788 | No |
| 9 | PGP | NA | PGP Entrez, Source | phosphoglycolate phosphatase | 15381 | -0.829 | -0.6055 | Yes |
| 10 | HYI | NA | HYI Entrez, Source | hydroxypyruvate isomerase homolog (E. coli) | 16101 | -1.090 | -0.5862 | Yes |
| 11 | ACO1 | NA | ACO1 Entrez, Source | aconitase 1, soluble | 16261 | -1.176 | -0.5311 | Yes |
| 12 | MTHFD1L | NA | MTHFD1L Entrez, Source | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 16917 | -1.605 | -0.4803 | Yes |
| 13 | MDH1 | NA | MDH1 Entrez, Source | malate dehydrogenase 1, NAD (soluble) | 16977 | -1.662 | -0.3932 | Yes |
| 14 | GLYCTK | NA | GLYCTK Entrez, Source | - | 16987 | -1.675 | -0.3026 | Yes |
| 15 | MTHFD2 | NA | MTHFD2 Entrez, Source | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 17201 | -1.913 | -0.2104 | Yes |
| 16 | HAO1 | NA | HAO1 Entrez, Source | hydroxyacid oxidase (glycolate oxidase) 1 | 17929 | -4.665 | 0.0028 | Yes |
