Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w1a_vs_wt_vs_wt.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp_repos |
| Phenotype | w1a_vs_wt.cls#ago1w1a_versus_ago1gfp_repos |
| Upregulated in class | ago1gfp |
| GeneSet | KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_GANGLIO_SERIES |
| Enrichment Score (ES) | -0.6121609 |
| Normalized Enrichment Score (NES) | -1.6030874 |
| Nominal p-value | 0.021505376 |
| FDR q-value | 0.1139626 |
| FWER p-Value | 0.346 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | ST3GAL2 | NA | ST3GAL2 Entrez, Source | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 | 3704 | 0.940 | -0.1497 | No |
| 2 | ST3GAL5 | NA | ST3GAL5 Entrez, Source | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 3845 | 0.907 | -0.1030 | No |
| 3 | B3GALT4 | NA | B3GALT4 Entrez, Source | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 | 5331 | 0.579 | -0.1509 | No |
| 4 | ST8SIA1 | NA | ST8SIA1 Entrez, Source | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 | 5902 | 0.487 | -0.1534 | No |
| 5 | ST6GALNAC6 | NA | ST6GALNAC6 Entrez, Source | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 | 6269 | 0.418 | -0.1486 | No |
| 6 | HEXB | NA | HEXB Entrez, Source | hexosaminidase B (beta polypeptide) | 6755 | 0.347 | -0.1548 | No |
| 7 | B4GALNT1 | NA | B4GALNT1 Entrez, Source | beta-1,4-N-acetyl-galactosaminyl transferase 1 | 8330 | 0.167 | -0.2323 | No |
| 8 | ST6GALNAC4 | NA | ST6GALNAC4 Entrez, Source | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 | 10521 | -0.034 | -0.3522 | No |
| 9 | GLB1 | NA | GLB1 Entrez, Source | galactosidase, beta 1 | 11427 | -0.127 | -0.3949 | No |
| 10 | SLC33A1 | NA | SLC33A1 Entrez, Source | solute carrier family 33 (acetyl-CoA transporter), member 1 | 14214 | -0.535 | -0.5179 | No |
| 11 | ST3GAL1 | NA | ST3GAL1 Entrez, Source | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 15909 | -1.010 | -0.5515 | Yes |
| 12 | ST8SIA5 | NA | ST8SIA5 Entrez, Source | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 | 16243 | -1.167 | -0.5000 | Yes |
| 13 | HEXA | NA | HEXA Entrez, Source | hexosaminidase A (alpha polypeptide) | 17383 | -2.194 | -0.4316 | Yes |
| 14 | ST6GALNAC5 | NA | ST6GALNAC5 Entrez, Source | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | 17689 | -3.114 | -0.2615 | Yes |
| 15 | ST6GALNAC3 | NA | ST6GALNAC3 Entrez, Source | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 17923 | -4.622 | 0.0032 | Yes |
