Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w1a_vs_wt_vs_wt.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp_repos |
| Phenotype | w1a_vs_wt.cls#ago1w1a_versus_ago1gfp_repos |
| Upregulated in class | ago1gfp |
| GeneSet | KEGG_GLYCEROLIPID_METABOLISM |
| Enrichment Score (ES) | -0.4253132 |
| Normalized Enrichment Score (NES) | -1.4426774 |
| Nominal p-value | 0.03214286 |
| FDR q-value | 0.1995711 |
| FWER p-Value | 0.799 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | GLA | NA | GLA Entrez, Source | galactosidase, alpha | 653 | 2.829 | 0.0267 | No |
| 2 | ALDH3A2 | NA | ALDH3A2 Entrez, Source | aldehyde dehydrogenase 3 family, member A2 | 1409 | 1.948 | 0.0281 | No |
| 3 | DGKD | NA | DGKD Entrez, Source | diacylglycerol kinase, delta 130kDa | 1880 | 1.625 | 0.0382 | No |
| 4 | CEL | NA | CEL Entrez, Source | carboxyl ester lipase (bile salt-stimulated lipase) | 2131 | 1.479 | 0.0573 | No |
| 5 | ALDH2 | NA | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 2317 | 1.406 | 0.0783 | No |
| 6 | AKR1B1 | NA | AKR1B1 Entrez, Source | aldo-keto reductase family 1, member B1 (aldose reductase) | 2471 | 1.337 | 0.0997 | No |
| 7 | DGKQ | NA | DGKQ Entrez, Source | diacylglycerol kinase, theta 110kDa | 2733 | 1.233 | 0.1126 | No |
| 8 | ALDH7A1 | NA | ALDH7A1 Entrez, Source | aldehyde dehydrogenase 7 family, member A1 | 2956 | 1.162 | 0.1262 | No |
| 9 | AGPAT1 | NA | AGPAT1 Entrez, Source | 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) | 3266 | 1.069 | 0.1328 | No |
| 10 | DGKA | NA | DGKA Entrez, Source | diacylglycerol kinase, alpha 80kDa | 4444 | 0.762 | 0.0842 | No |
| 11 | DGKB | NA | DGKB Entrez, Source | diacylglycerol kinase, beta 90kDa | 4602 | 0.725 | 0.0916 | No |
| 12 | AKR1A1 | NA | AKR1A1 Entrez, Source | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 4790 | 0.685 | 0.0965 | No |
| 13 | DGAT2 | NA | DGAT2 Entrez, Source | diacylglycerol O-acyltransferase homolog 2 (mouse) | 5051 | 0.632 | 0.0961 | No |
| 14 | DGKE | NA | DGKE Entrez, Source | diacylglycerol kinase, epsilon 64kDa | 5143 | 0.615 | 0.1048 | No |
| 15 | LIPF | NA | LIPF Entrez, Source | lipase, gastric | 7457 | 0.257 | -0.0185 | No |
| 16 | PNLIPRP2 | NA | PNLIPRP2 Entrez, Source | pancreatic lipase-related protein 2 | 8767 | 0.124 | -0.0887 | No |
| 17 | GK2 | NA | GK2 Entrez, Source | glycerol kinase 2 | 8860 | 0.115 | -0.0912 | No |
| 18 | LPL | NA | LPL Entrez, Source | lipoprotein lipase | 8999 | 0.099 | -0.0967 | No |
| 19 | MBOAT2 | NA | MBOAT2 Entrez, Source | membrane bound O-acyltransferase domain containing 2 | 9649 | 0.033 | -0.1322 | No |
| 20 | PNLIPRP1 | NA | PNLIPRP1 Entrez, Source | pancreatic lipase-related protein 1 | 9966 | 0.000 | -0.1498 | No |
| 21 | PNLIP | NA | PNLIP Entrez, Source | pancreatic lipase | 10144 | 0.000 | -0.1597 | No |
| 22 | AGPAT2 | NA | AGPAT2 Entrez, Source | 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) | 10856 | -0.064 | -0.1978 | No |
| 23 | AGPAT3 | NA | AGPAT3 Entrez, Source | 1-acylglycerol-3-phosphate O-acyltransferase 3 | 10924 | -0.073 | -0.2000 | No |
| 24 | LCLAT1 | NA | 11149 | -0.098 | -0.2102 | No | ||
| 25 | MBOAT1 | NA | MBOAT1 Entrez, Source | membrane bound O-acyltransferase domain containing 1 | 11190 | -0.102 | -0.2102 | No |
| 26 | AWAT2 | NA | 11691 | -0.153 | -0.2347 | No | ||
| 27 | DGAT1 | NA | DGAT1 Entrez, Source | diacylglycerol O-acyltransferase homolog 1 (mouse) | 11884 | -0.179 | -0.2414 | No |
| 28 | GK | NA | GK Entrez, Source | glycerol kinase | 11919 | -0.182 | -0.2392 | No |
| 29 | AGK | NA | 13416 | -0.384 | -0.3140 | No | ||
| 30 | ALDH9A1 | NA | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 13537 | -0.405 | -0.3117 | No |
| 31 | ALDH1B1 | NA | ALDH1B1 Entrez, Source | aldehyde dehydrogenase 1 family, member B1 | 14350 | -0.563 | -0.3444 | No |
| 32 | DGKZ | NA | DGKZ Entrez, Source | diacylglycerol kinase, zeta 104kDa | 15803 | -0.971 | -0.4036 | Yes |
| 33 | DGKH | NA | DGKH Entrez, Source | diacylglycerol kinase, eta | 15804 | -0.971 | -0.3820 | Yes |
| 34 | PNPLA3 | NA | PNPLA3 Entrez, Source | patatin-like phospholipase domain containing 3 | 16049 | -1.063 | -0.3718 | Yes |
| 35 | LIPC | NA | LIPC Entrez, Source | lipase, hepatic | 16178 | -1.127 | -0.3538 | Yes |
| 36 | AGPAT4 | NA | AGPAT4 Entrez, Source | 1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta) | 16981 | -1.671 | -0.3612 | Yes |
| 37 | GLYCTK | NA | GLYCTK Entrez, Source | - | 16987 | -1.675 | -0.3241 | Yes |
| 38 | DGKG | NA | DGKG Entrez, Source | diacylglycerol kinase, gamma 90kDa | 17331 | -2.092 | -0.2966 | Yes |
| 39 | GPAM | NA | GPAM Entrez, Source | glycerol-3-phosphate acyltransferase, mitochondrial | 17410 | -2.259 | -0.2505 | Yes |
| 40 | MGLL | NA | MGLL Entrez, Source | monoglyceride lipase | 17566 | -2.611 | -0.2009 | Yes |
| 41 | GPAT2 | NA | 17666 | -2.999 | -0.1394 | Yes | ||
| 42 | DGKI | NA | DGKI Entrez, Source | diacylglycerol kinase, iota | 17685 | -3.096 | -0.0713 | Yes |
| 43 | LIPG | NA | LIPG Entrez, Source | lipase, endothelial | 17824 | -3.929 | 0.0087 | Yes |
