Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w1a_vs_wt_vs_wt.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp_repos |
| Phenotype | w1a_vs_wt.cls#ago1w1a_versus_ago1gfp_repos |
| Upregulated in class | ago1gfp |
| GeneSet | KEGG_DORSO_VENTRAL_AXIS_FORMATION |
| Enrichment Score (ES) | -0.39879167 |
| Normalized Enrichment Score (NES) | -1.1725866 |
| Nominal p-value | 0.2197183 |
| FDR q-value | 0.58954376 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | SPIRE1 | NA | SPIRE1 Entrez, Source | spire homolog 1 (Drosophila) | 1827 | 1.650 | -0.0297 | No |
| 2 | PIWIL2 | NA | PIWIL2 Entrez, Source | piwi-like 2 (Drosophila) | 2746 | 1.228 | -0.0273 | No |
| 3 | SOS2 | NA | SOS2 Entrez, Source | son of sevenless homolog 2 (Drosophila) | 2927 | 1.172 | 0.0138 | No |
| 4 | ETV6 | NA | ETV6 Entrez, Source | ets variant gene 6 (TEL oncogene) | 3166 | 1.097 | 0.0485 | No |
| 5 | EGFR | NA | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 3428 | 1.020 | 0.0784 | No |
| 6 | NOTCH2 | NA | NOTCH2 Entrez, Source | Notch homolog 2 (Drosophila) | 3723 | 0.936 | 0.1029 | No |
| 7 | SOS1 | NA | SOS1 Entrez, Source | son of sevenless homolog 1 (Drosophila) | 3824 | 0.911 | 0.1371 | No |
| 8 | NOTCH1 | NA | NOTCH1 Entrez, Source | Notch homolog 1, translocation-associated (Drosophila) | 6392 | 0.398 | 0.0115 | No |
| 9 | CPEB1 | NA | CPEB1 Entrez, Source | cytoplasmic polyadenylation element binding protein 1 | 7084 | 0.305 | -0.0137 | No |
| 10 | KRAS | NA | KRAS Entrez, Source | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 7514 | 0.251 | -0.0266 | No |
| 11 | PIWIL1 | NA | PIWIL1 Entrez, Source | piwi-like 1 (Drosophila) | 7543 | 0.249 | -0.0173 | No |
| 12 | PIWIL3 | NA | PIWIL3 Entrez, Source | piwi-like 3 (Drosophila) | 8611 | 0.142 | -0.0705 | No |
| 13 | GRB2 | NA | GRB2 Entrez, Source | growth factor receptor-bound protein 2 | 12056 | -0.196 | -0.2538 | No |
| 14 | MAPK1 | NA | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 12360 | -0.233 | -0.2605 | No |
| 15 | PIWIL4 | NA | PIWIL4 Entrez, Source | piwi-like 4 (Drosophila) | 13234 | -0.353 | -0.2937 | No |
| 16 | ETV7 | NA | ETV7 Entrez, Source | ets variant gene 7 (TEL2 oncogene) | 13460 | -0.392 | -0.2891 | No |
| 17 | SPIRE2 | NA | SPIRE2 Entrez, Source | spire homolog 2 (Drosophila) | 14279 | -0.547 | -0.3108 | No |
| 18 | NOTCH3 | NA | NOTCH3 Entrez, Source | Notch homolog 3 (Drosophila) | 15021 | -0.726 | -0.3203 | No |
| 19 | MAPK3 | NA | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 16431 | -1.263 | -0.3437 | Yes |
| 20 | MAP2K1 | NA | MAP2K1 Entrez, Source | mitogen-activated protein kinase kinase 1 | 16504 | -1.300 | -0.2910 | Yes |
| 21 | FMN2 | NA | FMN2 Entrez, Source | formin 2 | 16515 | -1.311 | -0.2343 | Yes |
| 22 | ETS1 | NA | ETS1 Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | 16839 | -1.539 | -0.1851 | Yes |
| 23 | ETS2 | NA | ETS2 Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) | 17003 | -1.687 | -0.1206 | Yes |
| 24 | NOTCH4 | NA | NOTCH4 Entrez, Source | Notch homolog 4 (Drosophila) | 17843 | -4.009 | 0.0076 | Yes |
