Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w1a_vs_wt_vs_wt.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp_repos |
| Phenotype | w1a_vs_wt.cls#ago1w1a_versus_ago1gfp_repos |
| Upregulated in class | ago1w1a |
| GeneSet | KEGG_ASTHMA |
| Enrichment Score (ES) | 0.65224123 |
| Normalized Enrichment Score (NES) | 1.7580304 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.030493565 |
| FWER p-Value | 0.09 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | HLA-DRA | NA | HLA-DRA Entrez, Source | major histocompatibility complex, class II, DR alpha | 83 | 4.582 | 0.1216 | Yes |
| 2 | HLA-DRB1 | NA | HLA-DRB1 Entrez, Source | major histocompatibility complex, class II, DR beta 1 | 235 | 3.969 | 0.2225 | Yes |
| 3 | HLA-DPA1 | NA | HLA-DPA1 Entrez, Source | major histocompatibility complex, class II, DP alpha 1 | 345 | 3.598 | 0.3156 | Yes |
| 4 | HLA-DMA | NA | HLA-DMA Entrez, Source | major histocompatibility complex, class II, DM alpha | 556 | 3.030 | 0.3874 | Yes |
| 5 | HLA-DRB5 | NA | HLA-DRB5 Entrez, Source | major histocompatibility complex, class II, DR beta 5 | 611 | 2.898 | 0.4642 | Yes |
| 6 | HLA-DRB3 | NA | HLA-DRB3 Entrez, Source | major histocompatibility complex, class II, DR beta 3 | 916 | 2.438 | 0.5144 | Yes |
| 7 | HLA-DMB | NA | HLA-DMB Entrez, Source | major histocompatibility complex, class II, DM beta | 1107 | 2.215 | 0.5649 | Yes |
| 8 | HLA-DRB4 | NA | HLA-DRB4 Entrez, Source | major histocompatibility complex, class II, DR beta 4 | 1321 | 2.023 | 0.6087 | Yes |
| 9 | HLA-DOB | NA | HLA-DOB Entrez, Source | major histocompatibility complex, class II, DO beta | 1477 | 1.892 | 0.6522 | Yes |
| 10 | MS4A2 | NA | MS4A2 Entrez, Source | membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) | 5153 | 0.612 | 0.4644 | No |
| 11 | HLA-DPB1 | NA | HLA-DPB1 Entrez, Source | major histocompatibility complex, class II, DP beta 1 | 5159 | 0.612 | 0.4810 | No |
| 12 | IL13 | NA | IL13 Entrez, Source | interleukin 13 | 6827 | 0.339 | 0.3975 | No |
| 13 | HLA-DQB1 | NA | HLA-DQB1 Entrez, Source | major histocompatibility complex, class II, DQ beta 1 | 7133 | 0.297 | 0.3887 | No |
| 14 | FCER1A | NA | FCER1A Entrez, Source | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 7519 | 0.250 | 0.3741 | No |
| 15 | CD40LG | NA | CD40LG Entrez, Source | CD40 ligand (TNF superfamily, member 5, hyper-IgM syndrome) | 7609 | 0.242 | 0.3758 | No |
| 16 | HLA-DQA1 | NA | HLA-DQA1 Entrez, Source | major histocompatibility complex, class II, DQ alpha 1 | 7724 | 0.232 | 0.3759 | No |
| 17 | RNASE3 | NA | RNASE3 Entrez, Source | ribonuclease, RNase A family, 3 (eosinophil cationic protein) | 8014 | 0.201 | 0.3653 | No |
| 18 | HLA-DOA | NA | HLA-DOA Entrez, Source | major histocompatibility complex, class II, DO alpha | 8378 | 0.164 | 0.3496 | No |
| 19 | IL10 | NA | IL10 Entrez, Source | interleukin 10 | 9803 | 0.010 | 0.2705 | No |
| 20 | IL4 | NA | IL4 Entrez, Source | interleukin 4 | 9924 | 0.000 | 0.2639 | No |
| 21 | HLA-DQA2 | NA | HLA-DQA2 Entrez, Source | major histocompatibility complex, class II, DQ alpha 2 | 10636 | -0.045 | 0.2255 | No |
| 22 | TNF | NA | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 12645 | -0.269 | 0.1211 | No |
| 23 | IL3 | NA | IL3 Entrez, Source | interleukin 3 (colony-stimulating factor, multiple) | 13109 | -0.335 | 0.1045 | No |
| 24 | IL9 | NA | IL9 Entrez, Source | interleukin 9 | 13767 | -0.447 | 0.0802 | No |
| 25 | PRG2 | NA | PRG2 Entrez, Source | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 14401 | -0.574 | 0.0608 | No |
| 26 | FCER1G | NA | FCER1G Entrez, Source | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | 15054 | -0.735 | 0.0447 | No |
| 27 | EPX | NA | EPX Entrez, Source | eosinophil peroxidase | 16331 | -1.208 | 0.0069 | No |
| 28 | CD40 | NA | CD40 Entrez, Source | CD40 molecule, TNF receptor superfamily member 5 | 17681 | -3.081 | 0.0167 | No |
