Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w1a_vs_wt_vs_wt.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp_repos |
| Phenotype | w1a_vs_wt.cls#ago1w1a_versus_ago1gfp_repos |
| Upregulated in class | ago1w1a |
| GeneSet | KEGG_ALLOGRAFT_REJECTION |
| Enrichment Score (ES) | 0.5832141 |
| Normalized Enrichment Score (NES) | 1.6793834 |
| Nominal p-value | 0.0014641288 |
| FDR q-value | 0.054640673 |
| FWER p-Value | 0.242 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | HLA-DRA | NA | HLA-DRA Entrez, Source | major histocompatibility complex, class II, DR alpha | 83 | 4.582 | 0.0993 | Yes |
| 2 | HLA-DRB1 | NA | HLA-DRB1 Entrez, Source | major histocompatibility complex, class II, DR beta 1 | 235 | 3.969 | 0.1809 | Yes |
| 3 | HLA-DPA1 | NA | HLA-DPA1 Entrez, Source | major histocompatibility complex, class II, DP alpha 1 | 345 | 3.598 | 0.2564 | Yes |
| 4 | HLA-DMA | NA | HLA-DMA Entrez, Source | major histocompatibility complex, class II, DM alpha | 556 | 3.030 | 0.3134 | Yes |
| 5 | HLA-DRB5 | NA | HLA-DRB5 Entrez, Source | major histocompatibility complex, class II, DR beta 5 | 611 | 2.898 | 0.3761 | Yes |
| 6 | FAS | NA | FAS Entrez, Source | Fas (TNF receptor superfamily, member 6) | 733 | 2.679 | 0.4301 | Yes |
| 7 | HLA-DRB3 | NA | HLA-DRB3 Entrez, Source | major histocompatibility complex, class II, DR beta 3 | 916 | 2.438 | 0.4753 | Yes |
| 8 | HLA-DMB | NA | HLA-DMB Entrez, Source | major histocompatibility complex, class II, DM beta | 1107 | 2.215 | 0.5149 | Yes |
| 9 | HLA-DRB4 | NA | HLA-DRB4 Entrez, Source | major histocompatibility complex, class II, DR beta 4 | 1321 | 2.023 | 0.5489 | Yes |
| 10 | HLA-DOB | NA | HLA-DOB Entrez, Source | major histocompatibility complex, class II, DO beta | 1477 | 1.892 | 0.5832 | Yes |
| 11 | HLA-E | NA | HLA-E Entrez, Source | major histocompatibility complex, class I, E | 2705 | 1.243 | 0.5430 | No |
| 12 | PRF1 | NA | PRF1 Entrez, Source | perforin 1 (pore forming protein) | 3267 | 1.069 | 0.5360 | No |
| 13 | IL12A | NA | IL12A Entrez, Source | interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) | 3354 | 1.041 | 0.5548 | No |
| 14 | HLA-A | NA | HLA-A Entrez, Source | major histocompatibility complex, class I, A | 4503 | 0.747 | 0.5078 | No |
| 15 | FASLG | NA | FASLG Entrez, Source | Fas ligand (TNF superfamily, member 6) | 4608 | 0.723 | 0.5184 | No |
| 16 | HLA-C | NA | HLA-C Entrez, Source | major histocompatibility complex, class I, C | 4653 | 0.713 | 0.5321 | No |
| 17 | HLA-DPB1 | NA | HLA-DPB1 Entrez, Source | major histocompatibility complex, class II, DP beta 1 | 5159 | 0.612 | 0.5179 | No |
| 18 | IL12B | NA | IL12B Entrez, Source | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | 5356 | 0.576 | 0.5200 | No |
| 19 | HLA-F | NA | HLA-F Entrez, Source | major histocompatibility complex, class I, F | 5915 | 0.484 | 0.4999 | No |
| 20 | CD80 | NA | CD80 Entrez, Source | CD80 molecule | 6065 | 0.457 | 0.5019 | No |
| 21 | HLA-DQB1 | NA | HLA-DQB1 Entrez, Source | major histocompatibility complex, class II, DQ beta 1 | 7133 | 0.297 | 0.4492 | No |
| 22 | CD40LG | NA | CD40LG Entrez, Source | CD40 ligand (TNF superfamily, member 5, hyper-IgM syndrome) | 7609 | 0.242 | 0.4282 | No |
| 23 | HLA-DQA1 | NA | HLA-DQA1 Entrez, Source | major histocompatibility complex, class II, DQ alpha 1 | 7724 | 0.232 | 0.4271 | No |
| 24 | IL2 | NA | IL2 Entrez, Source | interleukin 2 | 8119 | 0.187 | 0.4094 | No |
| 25 | HLA-DOA | NA | HLA-DOA Entrez, Source | major histocompatibility complex, class II, DO alpha | 8378 | 0.164 | 0.3987 | No |
| 26 | IL10 | NA | IL10 Entrez, Source | interleukin 10 | 9803 | 0.010 | 0.3196 | No |
| 27 | IL4 | NA | IL4 Entrez, Source | interleukin 4 | 9924 | 0.000 | 0.3129 | No |
| 28 | HLA-DQA2 | NA | HLA-DQA2 Entrez, Source | major histocompatibility complex, class II, DQ alpha 2 | 10636 | -0.045 | 0.2743 | No |
| 29 | CD86 | NA | CD86 Entrez, Source | CD86 molecule | 11217 | -0.106 | 0.2444 | No |
| 30 | IFNG | NA | IFNG Entrez, Source | interferon, gamma | 11661 | -0.150 | 0.2231 | No |
| 31 | TNF | NA | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 12645 | -0.269 | 0.1745 | No |
| 32 | HLA-B | NA | HLA-B Entrez, Source | major histocompatibility complex, class I, B | 14110 | -0.511 | 0.1045 | No |
| 33 | HLA-G | NA | HLA-G Entrez, Source | HLA-G histocompatibility antigen, class I, G | 14436 | -0.581 | 0.0995 | No |
| 34 | CD28 | NA | CD28 Entrez, Source | CD28 molecule | 16374 | -1.233 | 0.0196 | No |
| 35 | CD40 | NA | CD40 Entrez, Source | CD40 molecule, TNF receptor superfamily member 5 | 17681 | -3.081 | 0.0167 | No |
