Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w1a_vs_wt_vs_wt.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp_repos |
| Phenotype | w1a_vs_wt.cls#ago1w1a_versus_ago1gfp_repos |
| Upregulated in class | ago1gfp |
| GeneSet | HALLMARK_MYC_TARGETS_V2 |
| Enrichment Score (ES) | -0.37945512 |
| Normalized Enrichment Score (NES) | -1.3583559 |
| Nominal p-value | 0.050179213 |
| FDR q-value | 0.058544923 |
| FWER p-Value | 0.193 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | SRM | NA | SRM Entrez, Source | spermidine synthase | 1067 | 2.259 | 0.0012 | No |
| 2 | HSPD1 | NA | HSPD1 Entrez, Source | heat shock 60kDa protein 1 (chaperonin) | 2160 | 1.465 | -0.0204 | No |
| 3 | HSPE1 | NA | HSPE1 Entrez, Source | heat shock 10kDa protein 1 (chaperonin 10) | 3247 | 1.076 | -0.0520 | No |
| 4 | IPO4 | NA | IPO4 Entrez, Source | importin 4 | 4050 | 0.856 | -0.0738 | No |
| 5 | BYSL | NA | BYSL Entrez, Source | bystin-like | 4333 | 0.786 | -0.0684 | No |
| 6 | SLC29A2 | NA | SLC29A2 Entrez, Source | solute carrier family 29 (nucleoside transporters), member 2 | 4640 | 0.716 | -0.0662 | No |
| 7 | IMP4 | NA | IMP4 Entrez, Source | IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) | 4665 | 0.711 | -0.0485 | No |
| 8 | NOP16 | NA | 5155 | 0.612 | -0.0593 | No | ||
| 9 | NOP56 | NA | 5679 | 0.521 | -0.0745 | No | ||
| 10 | NOP2 | NA | 5852 | 0.493 | -0.0708 | No | ||
| 11 | FARSA | NA | 6090 | 0.452 | -0.0719 | No | ||
| 12 | TCOF1 | NA | TCOF1 Entrez, Source | Treacher Collins-Franceschetti syndrome 1 | 6702 | 0.356 | -0.0964 | No |
| 13 | WDR74 | NA | WDR74 Entrez, Source | WD repeat domain 74 | 6736 | 0.350 | -0.0889 | No |
| 14 | RABEPK | NA | RABEPK Entrez, Source | Rab9 effector protein with kelch motifs | 7111 | 0.300 | -0.1017 | No |
| 15 | PPAN | NA | PPAN Entrez, Source | peter pan homolog (Drosophila) | 7802 | 0.223 | -0.1342 | No |
| 16 | MRTO4 | NA | 8125 | 0.186 | -0.1472 | No | ||
| 17 | NDUFAF4 | NA | 9005 | 0.098 | -0.1936 | No | ||
| 18 | MAP3K6 | NA | MAP3K6 Entrez, Source | mitogen-activated protein kinase kinase kinase 6 | 9008 | 0.098 | -0.1910 | No |
| 19 | SLC19A1 | NA | SLC19A1 Entrez, Source | solute carrier family 19 (folate transporter), member 1 | 9323 | 0.068 | -0.2067 | No |
| 20 | NPM1 | NA | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 9405 | 0.061 | -0.2096 | No |
| 21 | AIMP2 | NA | 9467 | 0.056 | -0.2115 | No | ||
| 22 | EXOSC5 | NA | EXOSC5 Entrez, Source | exosome component 5 | 10444 | -0.029 | -0.2652 | No |
| 23 | SUPV3L1 | NA | SUPV3L1 Entrez, Source | suppressor of var1, 3-like 1 (S. cerevisiae) | 10868 | -0.065 | -0.2870 | No |
| 24 | TMEM97 | NA | TMEM97 Entrez, Source | transmembrane protein 97 | 11080 | -0.088 | -0.2964 | No |
| 25 | NOC4L | NA | NOC4L Entrez, Source | nucleolar complex associated 4 homolog (S. cerevisiae) | 11091 | -0.091 | -0.2945 | No |
| 26 | RRP12 | NA | 11150 | -0.099 | -0.2951 | No | ||
| 27 | DDX18 | NA | DDX18 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 12398 | -0.238 | -0.3583 | No |
| 28 | PA2G4 | NA | PA2G4 Entrez, Source | proliferation-associated 2G4, 38kDa | 12564 | -0.258 | -0.3606 | No |
| 29 | MYBBP1A | NA | MYBBP1A Entrez, Source | MYB binding protein (P160) 1a | 12607 | -0.264 | -0.3558 | No |
| 30 | GRWD1 | NA | GRWD1 Entrez, Source | glutamate-rich WD repeat containing 1 | 12664 | -0.273 | -0.3516 | No |
| 31 | LAS1L | NA | LAS1L Entrez, Source | LAS1-like (S. cerevisiae) | 12807 | -0.291 | -0.3517 | No |
| 32 | PHB | NA | PHB Entrez, Source | prohibitin | 13006 | -0.320 | -0.3542 | No |
| 33 | PES1 | NA | PES1 Entrez, Source | pescadillo homolog 1, containing BRCT domain (zebrafish) | 13034 | -0.324 | -0.3470 | No |
| 34 | TBRG4 | NA | TBRG4 Entrez, Source | transforming growth factor beta regulator 4 | 13587 | -0.413 | -0.3667 | No |
| 35 | UTP20 | NA | UTP20 Entrez, Source | UTP20, small subunit (SSU) processome component, homolog (yeast) | 13817 | -0.455 | -0.3672 | Yes |
| 36 | RCL1 | NA | RCL1 Entrez, Source | RNA terminal phosphate cyclase-like 1 | 13864 | -0.465 | -0.3573 | Yes |
| 37 | PLK1 | NA | PLK1 Entrez, Source | polo-like kinase 1 (Drosophila) | 13882 | -0.468 | -0.3456 | Yes |
| 38 | PPRC1 | NA | PPRC1 Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator-related 1 | 13903 | -0.471 | -0.3341 | Yes |
| 39 | UNG | NA | UNG Entrez, Source | uracil-DNA glycosylase | 14205 | -0.533 | -0.3366 | Yes |
| 40 | WDR43 | NA | WDR43 Entrez, Source | WD repeat domain 43 | 14617 | -0.623 | -0.3428 | Yes |
| 41 | PRMT3 | NA | PRMT3 Entrez, Source | protein arginine methyltransferase 3 | 14644 | -0.628 | -0.3273 | Yes |
| 42 | CDK4 | NA | CDK4 Entrez, Source | cyclin-dependent kinase 4 | 14970 | -0.714 | -0.3263 | Yes |
| 43 | RRP9 | NA | 15068 | -0.738 | -0.3118 | Yes | ||
| 44 | NIP7 | NA | NIP7 Entrez, Source | nuclear import 7 homolog (S. cerevisiae) | 15136 | -0.755 | -0.2953 | Yes |
| 45 | MYC | NA | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 15151 | -0.760 | -0.2757 | Yes |
| 46 | SORD | NA | SORD Entrez, Source | sorbitol dehydrogenase | 15170 | -0.765 | -0.2561 | Yes |
| 47 | MCM4 | NA | MCM4 Entrez, Source | MCM4 minichromosome maintenance deficient 4 (S. cerevisiae) | 15270 | -0.795 | -0.2403 | Yes |
| 48 | PUS1 | NA | PUS1 Entrez, Source | pseudouridylate synthase 1 | 15317 | -0.810 | -0.2210 | Yes |
| 49 | PLK4 | NA | PLK4 Entrez, Source | polo-like kinase 4 (Drosophila) | 15455 | -0.849 | -0.2059 | Yes |
| 50 | CBX3 | NA | CBX3 Entrez, Source | chromobox homolog 3 (HP1 gamma homolog, Drosophila) | 15596 | -0.894 | -0.1896 | Yes |
| 51 | TFB2M | NA | TFB2M Entrez, Source | transcription factor B2, mitochondrial | 15949 | -1.028 | -0.1817 | Yes |
| 52 | MCM5 | NA | MCM5 Entrez, Source | MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) | 16100 | -1.089 | -0.1608 | Yes |
| 53 | DCTPP1 | NA | 16105 | -1.093 | -0.1316 | Yes | ||
| 54 | NOLC1 | NA | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 16254 | -1.172 | -0.1084 | Yes |
| 55 | GNL3 | NA | GNL3 Entrez, Source | guanine nucleotide binding protein-like 3 (nucleolar) | 16304 | -1.194 | -0.0790 | Yes |
| 56 | HK2 | NA | HK2 Entrez, Source | hexokinase 2 | 17109 | -1.798 | -0.0756 | Yes |
| 57 | MPHOSPH10 | NA | MPHOSPH10 Entrez, Source | M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) | 17342 | -2.116 | -0.0316 | Yes |
| 58 | DUSP2 | NA | DUSP2 Entrez, Source | dual specificity phosphatase 2 | 17528 | -2.499 | 0.0252 | Yes |
