Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w1a_vs_wt_vs_wt.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp_repos |
| Phenotype | w1a_vs_wt.cls#ago1w1a_versus_ago1gfp_repos |
| Upregulated in class | ago1w1a |
| GeneSet | HALLMARK_ANGIOGENESIS |
| Enrichment Score (ES) | 0.49013543 |
| Normalized Enrichment Score (NES) | 1.3961446 |
| Nominal p-value | 0.06849315 |
| FDR q-value | 0.048573297 |
| FWER p-Value | 0.556 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | S100A4 | NA | S100A4 Entrez, Source | S100 calcium binding protein A4 | 167 | 4.213 | 0.0651 | Yes |
| 2 | JAG1 | NA | JAG1 Entrez, Source | jagged 1 (Alagille syndrome) | 309 | 3.715 | 0.1228 | Yes |
| 3 | THBD | NA | THBD Entrez, Source | thrombomodulin | 406 | 3.436 | 0.1781 | Yes |
| 4 | TNFRSF21 | NA | TNFRSF21 Entrez, Source | tumor necrosis factor receptor superfamily, member 21 | 446 | 3.302 | 0.2342 | Yes |
| 5 | JAG2 | NA | JAG2 Entrez, Source | jagged 2 | 548 | 3.041 | 0.2822 | Yes |
| 6 | LUM | NA | LUM Entrez, Source | lumican | 561 | 3.021 | 0.3349 | Yes |
| 7 | FGFR1 | NA | FGFR1 Entrez, Source | fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) | 658 | 2.821 | 0.3793 | Yes |
| 8 | SPP1 | NA | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 952 | 2.395 | 0.4053 | Yes |
| 9 | VEGFA | NA | 1354 | 1.991 | 0.4181 | Yes | ||
| 10 | LRPAP1 | NA | LRPAP1 Entrez, Source | low density lipoprotein receptor-related protein associated protein 1 | 1598 | 1.810 | 0.4365 | Yes |
| 11 | ITGAV | NA | ITGAV Entrez, Source | integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) | 1618 | 1.791 | 0.4670 | Yes |
| 12 | NRP1 | NA | NRP1 Entrez, Source | neuropilin 1 | 1861 | 1.634 | 0.4824 | Yes |
| 13 | TIMP1 | NA | TIMP1 Entrez, Source | TIMP metallopeptidase inhibitor 1 | 2184 | 1.455 | 0.4901 | Yes |
| 14 | KCNJ8 | NA | KCNJ8 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 8 | 2873 | 1.191 | 0.4728 | No |
| 15 | PGLYRP1 | NA | PGLYRP1 Entrez, Source | peptidoglycan recognition protein 1 | 3132 | 1.109 | 0.4780 | No |
| 16 | COL3A1 | NA | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 4743 | 0.694 | 0.4005 | No |
| 17 | VAV2 | NA | VAV2 Entrez, Source | vav 2 oncogene | 5030 | 0.636 | 0.3958 | No |
| 18 | VTN | NA | VTN Entrez, Source | vitronectin | 5133 | 0.617 | 0.4010 | No |
| 19 | PF4 | NA | PF4 Entrez, Source | platelet factor 4 (chemokine (C-X-C motif) ligand 4) | 5200 | 0.605 | 0.4080 | No |
| 20 | STC1 | NA | STC1 Entrez, Source | stanniocalcin 1 | 6566 | 0.376 | 0.3386 | No |
| 21 | APOH | NA | APOH Entrez, Source | apolipoprotein H (beta-2-glycoprotein I) | 7194 | 0.288 | 0.3087 | No |
| 22 | FSTL1 | NA | FSTL1 Entrez, Source | follistatin-like 1 | 7323 | 0.271 | 0.3064 | No |
| 23 | POSTN | NA | POSTN Entrez, Source | periostin, osteoblast specific factor | 8064 | 0.194 | 0.2686 | No |
| 24 | PTK2 | NA | PTK2 Entrez, Source | PTK2 protein tyrosine kinase 2 | 8777 | 0.123 | 0.2311 | No |
| 25 | LPL | NA | LPL Entrez, Source | lipoprotein lipase | 8999 | 0.099 | 0.2205 | No |
| 26 | OLR1 | NA | OLR1 Entrez, Source | oxidised low density lipoprotein (lectin-like) receptor 1 | 9417 | 0.059 | 0.1983 | No |
| 27 | MSX1 | NA | MSX1 Entrez, Source | msh homeobox homolog 1 (Drosophila) | 9625 | 0.037 | 0.1874 | No |
| 28 | CXCL6 | NA | CXCL6 Entrez, Source | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 11409 | -0.125 | 0.0903 | No |
| 29 | PRG2 | NA | PRG2 Entrez, Source | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 14401 | -0.574 | -0.0663 | No |
| 30 | APP | NA | APP Entrez, Source | amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) | 15338 | -0.815 | -0.1040 | No |
| 31 | COL5A2 | NA | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 15422 | -0.840 | -0.0938 | No |
| 32 | CCND2 | NA | CCND2 Entrez, Source | cyclin D2 | 16961 | -1.643 | -0.1505 | No |
| 33 | SERPINA5 | NA | SERPINA5 Entrez, Source | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 17155 | -1.847 | -0.1287 | No |
| 34 | PDGFA | NA | PDGFA Entrez, Source | platelet-derived growth factor alpha polypeptide | 17396 | -2.217 | -0.1029 | No |
| 35 | SLCO2A1 | NA | SLCO2A1 Entrez, Source | solute carrier organic anion transporter family, member 2A1 | 17699 | -3.143 | -0.0643 | No |
| 36 | VCAN | NA | 17912 | -4.524 | 0.0038 | No |
