Motif ID: ZNF8

Z-value: 0.214


Transcription factors associated with ZNF8:

Gene SymbolEntrez IDGene Name
ZNF8 ENSG00000083842.8 ZNF8
ZNF8 ENSG00000273439.1 ZNF8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZNF8hg19_v2_chr19_+_58790314_58790358-0.482.0e-01Click!


Activity profile for motif ZNF8.

activity profile for motif ZNF8


Sorted Z-values histogram for motif ZNF8

Sorted Z-values for motif ZNF8



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF8

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_26056695 0.157 ENST00000343677.2
 HIST1H1C
histone cluster 1, H1c
chr5_-_93447333 0.136 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
 FAM172A


family with sequence similarity 172, member A


chrX_+_102631248 0.106 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
 NGFRAP1


nerve growth factor receptor (TNFRSF16) associated protein 1


chr2_-_240322643 0.105 ENST00000345617.3
 HDAC4
histone deacetylase 4
chr19_-_18392422 0.102 ENST00000252818.3
 JUND
jun D proto-oncogene
chr2_-_240322685 0.100 ENST00000544989.1
 HDAC4
histone deacetylase 4
chr8_-_61429315 0.096 ENST00000530725.1
ENST00000532232.1
 RP11-163N6.2

RP11-163N6.2

chr16_+_21964662 0.096 ENST00000561553.1
ENST00000565331.1
 UQCRC2

ubiquinol-cytochrome c reductase core protein II

chr1_-_235292250 0.087 ENST00000366607.4
 TOMM20
translocase of outer mitochondrial membrane 20 homolog (yeast)
chr13_+_45563721 0.084 ENST00000361121.2
 GPALPP1
GPALPP motifs containing 1
chr2_+_240323439 0.081 ENST00000428471.1
ENST00000413029.1
 AC062017.1

Uncharacterized protein

chr1_+_211500129 0.071 ENST00000427925.2
ENST00000261464.5
 TRAF5

TNF receptor-associated factor 5

chr5_+_138677515 0.068 ENST00000265192.4
ENST00000511706.1
 PAIP2

poly(A) binding protein interacting protein 2

chr17_+_34136459 0.056 ENST00000588240.1
ENST00000590273.1
ENST00000588441.1
ENST00000587272.1
ENST00000592237.1
ENST00000311979.3
 TAF15





TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa





chr9_-_94711007 0.054 ENST00000375715.1
 ROR2
receptor tyrosine kinase-like orphan receptor 2
chr4_+_170541660 0.052 ENST00000513761.1
ENST00000347613.4
 CLCN3

chloride channel, voltage-sensitive 3

chr5_+_10353780 0.051 ENST00000449913.2
ENST00000503788.1
ENST00000274140.5
 MARCH6


membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase


chr22_+_30163340 0.051 ENST00000330029.6
ENST00000401406.3
 UQCR10

ubiquinol-cytochrome c reductase, complex III subunit X

chr4_-_186347099 0.051 ENST00000505357.1
ENST00000264689.6
 UFSP2

UFM1-specific peptidase 2

chr11_-_61560254 0.048 ENST00000543510.1
 TMEM258
transmembrane protein 258
chr19_-_55652290 0.044 ENST00000589745.1
 TNNT1
troponin T type 1 (skeletal, slow)
chr6_+_18155560 0.044 ENST00000546309.2
ENST00000388870.2
ENST00000397244.1
 KDM1B


lysine (K)-specific demethylase 1B


chr10_-_73611046 0.043 ENST00000394934.1
ENST00000394936.3
 PSAP

prosaposin

chr4_+_170541835 0.042 ENST00000504131.2
 CLCN3
chloride channel, voltage-sensitive 3
chr12_-_46662772 0.042 ENST00000549049.1
ENST00000439706.1
ENST00000398637.5
 SLC38A1


solute carrier family 38, member 1


chr22_+_37415776 0.042 ENST00000341116.3
ENST00000429360.2
ENST00000404393.1
 MPST


mercaptopyruvate sulfurtransferase


chr17_+_75181292 0.042 ENST00000431431.2
 SEC14L1
SEC14-like 1 (S. cerevisiae)
chr22_+_37415676 0.041 ENST00000401419.3
 MPST
mercaptopyruvate sulfurtransferase
chr14_+_105941118 0.041 ENST00000550577.1
ENST00000538259.2
 CRIP2

cysteine-rich protein 2

chr17_+_48624450 0.040 ENST00000006658.6
ENST00000356488.4
ENST00000393244.3
 SPATA20


spermatogenesis associated 20


chr22_-_37415475 0.040 ENST00000403892.3
ENST00000249042.3
ENST00000438203.1
 TST


thiosulfate sulfurtransferase (rhodanese)


chr22_+_37415728 0.039 ENST00000404802.3
 MPST
mercaptopyruvate sulfurtransferase
chr4_+_170541678 0.037 ENST00000360642.3
ENST00000512813.1
 CLCN3

chloride channel, voltage-sensitive 3

chr12_-_74686314 0.036 ENST00000551210.1
ENST00000515416.2
ENST00000549905.1
 RP11-81H3.2


RP11-81H3.2


chr22_+_37415700 0.036 ENST00000397129.1
 MPST
mercaptopyruvate sulfurtransferase
chr6_-_31763408 0.035 ENST00000444930.2
 VARS
valyl-tRNA synthetase
chr7_+_117824086 0.032 ENST00000249299.2
ENST00000424702.1
 NAA38

N(alpha)-acetyltransferase 38, NatC auxiliary subunit

chr3_-_9994021 0.032 ENST00000411976.2
ENST00000412055.1
 PRRT3

proline-rich transmembrane protein 3

chr10_-_1034237 0.031 ENST00000381466.1
 AL359878.1
Uncharacterized protein
chr16_+_68573116 0.029 ENST00000570495.1
ENST00000563169.2
ENST00000564323.1
ENST00000562156.1
ENST00000573685.1
 ZFP90




ZFP90 zinc finger protein




chr6_+_116601265 0.028 ENST00000452085.3
 DSE
dermatan sulfate epimerase
chr2_+_173600514 0.025 ENST00000264111.6
 RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr19_+_37998031 0.024 ENST00000586138.1
ENST00000588578.1
ENST00000587986.1
 ZNF793


zinc finger protein 793


chr1_+_70671363 0.024 ENST00000370951.1
ENST00000370950.3
ENST00000405432.1
ENST00000454435.2
 SRSF11



serine/arginine-rich splicing factor 11



chr6_-_116601044 0.022 ENST00000368608.3
 TSPYL1
TSPY-like 1
chr8_+_61429416 0.022 ENST00000262646.7
ENST00000531289.1
 RAB2A

RAB2A, member RAS oncogene family

chr2_+_173600565 0.022 ENST00000397081.3
 RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr6_+_88117683 0.021 ENST00000369562.4
 C6ORF165
UPF0704 protein C6orf165
chrX_+_129535937 0.021 ENST00000305536.6
ENST00000370947.1
 RBMX2

RNA binding motif protein, X-linked 2

chr8_-_109260897 0.019 ENST00000521297.1
ENST00000519030.1
ENST00000521440.1
ENST00000518345.1
ENST00000519627.1
ENST00000220849.5
 EIF3E





eukaryotic translation initiation factor 3, subunit E





chr22_-_30162924 0.018 ENST00000344318.3
ENST00000397781.3
 ZMAT5

zinc finger, matrin-type 5

chr13_+_53029564 0.018 ENST00000468284.1
ENST00000378034.3
ENST00000258607.5
ENST00000378037.5
 CKAP2



cytoskeleton associated protein 2



chr1_-_55266865 0.016 ENST00000371274.4
 TTC22
tetratricopeptide repeat domain 22
chr11_+_46402583 0.015 ENST00000359803.3
 MDK
midkine (neurite growth-promoting factor 2)
chr19_-_5903714 0.015 ENST00000252675.5
ENST00000308961.4
ENST00000592634.1
ENST00000418389.2
ENST00000586349.1
ENST00000585661.1
 FUT5
NDUFA11


AC024592.12

fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa


Uncharacterized protein

chr5_-_43515125 0.015 ENST00000509489.1
 C5orf34
chromosome 5 open reading frame 34
chr5_-_137911049 0.013 ENST00000297185.3
 HSPA9
heat shock 70kDa protein 9 (mortalin)
chr5_+_102455968 0.013 ENST00000358359.3
 PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr11_+_46638805 0.012 ENST00000434074.1
ENST00000312040.4
ENST00000451945.1
 ATG13


autophagy related 13


chr1_-_55266926 0.012 ENST00000371276.4
 TTC22
tetratricopeptide repeat domain 22
chr13_+_21750780 0.012 ENST00000309594.4
 MRP63
mitochondrial ribosomal protein 63
chr9_-_32552551 0.012 ENST00000360538.2
ENST00000379858.1
 TOPORS

topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase

chr11_+_13690200 0.011 ENST00000354817.3
 FAR1
fatty acyl CoA reductase 1
chr16_-_53537105 0.009 ENST00000568596.1
ENST00000570004.1
ENST00000564497.1
ENST00000300245.4
ENST00000394657.7
 AKTIP




AKT interacting protein




chr7_-_74489609 0.009 ENST00000329959.4
ENST00000503250.2
ENST00000543840.1
 WBSCR16


Williams-Beuren syndrome chromosome region 16


chr12_+_104235229 0.008 ENST00000551650.1
 RP11-650K20.3
Uncharacterized protein
chr1_-_246670519 0.006 ENST00000388985.4
ENST00000490107.1
 SMYD3

SET and MYND domain containing 3

chr1_-_246670614 0.006 ENST00000403792.3
 SMYD3
SET and MYND domain containing 3
chr17_+_48585794 0.005 ENST00000576179.1
ENST00000419930.1
 MYCBPAP

MYCBP associated protein

chr2_-_105946491 0.005 ENST00000393359.2
 TGFBRAP1
transforming growth factor, beta receptor associated protein 1
chr12_-_46662888 0.005 ENST00000546893.1
 SLC38A1
solute carrier family 38, member 1
chr10_+_1034338 0.004 ENST00000360803.4
ENST00000538293.1
 GTPBP4

GTP binding protein 4

chr1_+_6615241 0.004 ENST00000333172.6
ENST00000328191.4
ENST00000351136.3
 TAS1R1


taste receptor, type 1, member 1


chr17_+_48585902 0.003 ENST00000452039.1
 MYCBPAP
MYCBP associated protein
chr10_+_1034646 0.002 ENST00000360059.5
ENST00000545048.1
 GTPBP4

GTP binding protein 4

chr17_+_48585745 0.001 ENST00000323776.5
 MYCBPAP
MYCBP associated protein
chrX_+_128913906 0.001 ENST00000356892.3
 SASH3
SAM and SH3 domain containing 3
chr2_+_169926047 0.000 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
 DHRS9


dehydrogenase/reductase (SDR family) member 9



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0009439 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.2 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.0 0.1 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 0.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.0 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)