Motif ID: ZNF740_ZNF219

Z-value: 0.921

Transcription factors associated with ZNF740_ZNF219:

Gene SymbolEntrez IDGene Name
ZNF219 ENSG00000165804.11 ZNF219
ZNF740 ENSG00000139651.9 ZNF740

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZNF219hg19_v2_chr14_-_21567009_21567173-0.964.8e-05Click!
ZNF740hg19_v2_chr12_+_53574464_53574539-0.571.1e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF740_ZNF219

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_55795493 1.332 ENST00000309383.1
BRSK1
BR serine/threonine kinase 1
chr2_-_148779106 0.811 ENST00000416719.1
ENST00000264169.2
ORC4

origin recognition complex, subunit 4

chr2_-_148778323 0.785 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
ORC4



origin recognition complex, subunit 4



chr2_-_217236750 0.591 ENST00000273067.4
MARCH4
membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
chr10_+_76586348 0.551 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
KAT6B


K(lysine) acetyltransferase 6B


chr1_+_164528866 0.533 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr1_-_98511756 0.496 ENST00000602984.1
ENST00000602852.1
MIR137HG

MIR137 host gene (non-protein coding)

chr6_-_110500905 0.452 ENST00000392587.2
WASF1
WAS protein family, member 1
chr6_-_110500826 0.445 ENST00000265601.3
ENST00000447287.1
ENST00000444391.1
WASF1


WAS protein family, member 1


chr15_+_39873268 0.435 ENST00000397591.2
ENST00000260356.5
THBS1

thrombospondin 1

chr6_+_149638876 0.427 ENST00000392282.1
TAB2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr9_-_140115775 0.417 ENST00000391553.1
ENST00000392827.1
RNF208

ring finger protein 208

chr1_-_38273840 0.366 ENST00000373044.2
YRDC
yrdC N(6)-threonylcarbamoyltransferase domain containing
chr16_+_81478775 0.352 ENST00000537098.3
CMIP
c-Maf inducing protein
chr12_-_6715808 0.339 ENST00000545584.1
CHD4
chromodomain helicase DNA binding protein 4
chr12_-_96184913 0.336 ENST00000538383.1
NTN4
netrin 4
chr1_-_19283163 0.335 ENST00000455833.2
IFFO2
intermediate filament family orphan 2
chr8_-_101734170 0.330 ENST00000522387.1
ENST00000518196.1
PABPC1

poly(A) binding protein, cytoplasmic 1

chr10_-_108924284 0.318 ENST00000344440.6
ENST00000263054.6
SORCS1

sortilin-related VPS10 domain containing receptor 1

chr2_-_148778258 0.316 ENST00000392857.5
ENST00000457954.1
ENST00000392858.1
ENST00000542387.1
ORC4



origin recognition complex, subunit 4



chr4_-_111119804 0.314 ENST00000394607.3
ENST00000302274.3
ELOVL6

ELOVL fatty acid elongase 6

chr14_-_81687197 0.314 ENST00000553612.1
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr14_-_54418598 0.309 ENST00000609748.1
ENST00000558961.1
BMP4

bone morphogenetic protein 4

chr2_-_161349909 0.302 ENST00000392753.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr3_+_184032919 0.299 ENST00000427845.1
ENST00000342981.4
ENST00000319274.6
EIF4G1


eukaryotic translation initiation factor 4 gamma, 1


chr17_-_27277615 0.290 ENST00000583747.1
ENST00000584236.1
PHF12

PHD finger protein 12

chr1_-_150208498 0.286 ENST00000314136.8
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr18_+_56530136 0.285 ENST00000591083.1
ZNF532
zinc finger protein 532
chr17_-_42276574 0.279 ENST00000589805.1
ATXN7L3
ataxin 7-like 3
chr11_-_85779971 0.273 ENST00000393346.3
PICALM
phosphatidylinositol binding clathrin assembly protein
chr17_-_42277203 0.270 ENST00000587097.1
ATXN7L3
ataxin 7-like 3
chr2_-_220117867 0.269 ENST00000456818.1
ENST00000447205.1
TUBA4A

tubulin, alpha 4a

chr12_-_96184533 0.268 ENST00000343702.4
ENST00000344911.4
NTN4

netrin 4

chr12_+_53846612 0.266 ENST00000551104.1
PCBP2
poly(rC) binding protein 2
chr14_-_23451845 0.264 ENST00000262713.2
AJUBA
ajuba LIM protein
chr2_+_36582857 0.263 ENST00000280527.2
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chrX_-_119695279 0.260 ENST00000336592.6
CUL4B
cullin 4B
chr6_+_20403997 0.258 ENST00000535432.1
E2F3
E2F transcription factor 3
chr1_-_150208412 0.253 ENST00000532744.1
ENST00000369114.5
ENST00000369115.2
ENST00000369116.4
ANP32E



acidic (leucine-rich) nuclear phosphoprotein 32 family, member E



chr9_-_86153218 0.243 ENST00000304195.3
ENST00000376438.1
FRMD3

FERM domain containing 3

chr12_+_56401268 0.243 ENST00000262032.5
IKZF4
IKAROS family zinc finger 4 (Eos)
chr15_+_101142722 0.238 ENST00000332783.7
ENST00000558747.1
ENST00000343276.4
ASB7


ankyrin repeat and SOCS box containing 7


chr11_-_85780086 0.234 ENST00000532317.1
ENST00000528256.1
ENST00000526033.1
PICALM


phosphatidylinositol binding clathrin assembly protein


chr20_-_52210368 0.234 ENST00000371471.2
ZNF217
zinc finger protein 217
chr17_+_56160768 0.232 ENST00000579991.2
DYNLL2
dynein, light chain, LC8-type 2
chr3_+_184033135 0.231 ENST00000424196.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr1_-_151431674 0.230 ENST00000531094.1
POGZ
pogo transposable element with ZNF domain
chr8_+_120428546 0.226 ENST00000259526.3
NOV
nephroblastoma overexpressed
chr8_-_101734308 0.225 ENST00000519004.1
ENST00000519363.1
ENST00000520142.1
PABPC1


poly(A) binding protein, cytoplasmic 1


chr8_+_26149274 0.225 ENST00000522535.1
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr1_-_150208320 0.223 ENST00000534220.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr19_+_41725088 0.223 ENST00000301178.4
AXL
AXL receptor tyrosine kinase
chr13_-_52026730 0.222 ENST00000420668.2
INTS6
integrator complex subunit 6
chr22_+_41487711 0.220 ENST00000263253.7
EP300
E1A binding protein p300
chr1_-_150208363 0.215 ENST00000436748.2
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr2_-_56150910 0.213 ENST00000424836.2
ENST00000438672.1
ENST00000440439.1
ENST00000429909.1
ENST00000424207.1
ENST00000452337.1
ENST00000355426.3
ENST00000439193.1
ENST00000421664.1
EFEMP1








EGF containing fibulin-like extracellular matrix protein 1








chr7_+_26241310 0.211 ENST00000396386.2
CBX3
chromobox homolog 3
chr17_+_65821636 0.211 ENST00000544778.2
BPTF
bromodomain PHD finger transcription factor
chr13_-_52027134 0.211 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6




integrator complex subunit 6




chr8_+_87354945 0.209 ENST00000517970.1
WWP1
WW domain containing E3 ubiquitin protein ligase 1
chr15_+_98503922 0.207 ENST00000268042.6
ARRDC4
arrestin domain containing 4
chr10_+_69865866 0.207 ENST00000354393.2
MYPN
myopalladin
chr2_-_230786619 0.205 ENST00000389045.3
ENST00000409677.1
TRIP12

thyroid hormone receptor interactor 12

chr19_+_41725140 0.203 ENST00000359092.3
AXL
AXL receptor tyrosine kinase
chr15_-_65477637 0.203 ENST00000300107.3
CLPX
caseinolytic mitochondrial matrix peptidase chaperone subunit
chr2_+_149402553 0.203 ENST00000258484.6
ENST00000409654.1
EPC2

enhancer of polycomb homolog 2 (Drosophila)

chr1_+_203765437 0.202 ENST00000550078.1
ZBED6
zinc finger, BED-type containing 6
chr17_+_37618257 0.201 ENST00000447079.4
CDK12
cyclin-dependent kinase 12
chr3_+_189507460 0.200 ENST00000434928.1
TP63
tumor protein p63
chr17_+_45727204 0.200 ENST00000290158.4
KPNB1
karyopherin (importin) beta 1
chr16_+_29817841 0.197 ENST00000322945.6
ENST00000562337.1
ENST00000566906.2
ENST00000563402.1
ENST00000219782.6
MAZ




MYC-associated zinc finger protein (purine-binding transcription factor)




chr18_+_72265084 0.196 ENST00000582337.1
ZNF407
zinc finger protein 407
chr11_+_77532155 0.196 ENST00000532481.1
ENST00000526415.1
ENST00000393427.2
ENST00000527134.1
ENST00000304716.8
AAMDC




adipogenesis associated, Mth938 domain containing




chr2_-_55277436 0.196 ENST00000354474.6
RTN4
reticulon 4
chr12_+_96588143 0.196 ENST00000228741.3
ENST00000547249.1
ELK3

ELK3, ETS-domain protein (SRF accessory protein 2)

chr18_-_51750948 0.195 ENST00000583046.1
ENST00000398398.2
MBD2

methyl-CpG binding domain protein 2

chr12_-_6716534 0.195 ENST00000544484.1
ENST00000309577.6
ENST00000357008.2
CHD4


chromodomain helicase DNA binding protein 4


chr15_-_41408339 0.194 ENST00000401393.3
INO80
INO80 complex subunit
chr7_+_26241325 0.191 ENST00000456948.1
ENST00000409747.1
CBX3

chromobox homolog 3

chr6_-_139308777 0.187 ENST00000529597.1
ENST00000415951.2
ENST00000367663.4
ENST00000409812.2
REPS1



RALBP1 associated Eps domain containing 1



chr22_-_36236623 0.185 ENST00000405409.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr14_-_81687575 0.185 ENST00000434192.2
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr1_-_21503337 0.185 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
EIF4G3



eukaryotic translation initiation factor 4 gamma, 3



chr7_-_92465868 0.184 ENST00000424848.2
CDK6
cyclin-dependent kinase 6
chr12_-_6716569 0.183 ENST00000544040.1
ENST00000545942.1
CHD4

chromodomain helicase DNA binding protein 4

chr12_+_96588368 0.180 ENST00000547860.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr3_-_149688655 0.180 ENST00000461930.1
ENST00000423691.2
ENST00000490975.1
ENST00000461868.1
ENST00000452853.2
PFN2




profilin 2




chr1_+_26737292 0.178 ENST00000254231.4
LIN28A
lin-28 homolog A (C. elegans)
chr1_-_205782304 0.178 ENST00000367137.3
SLC41A1
solute carrier family 41 (magnesium transporter), member 1
chr5_+_154173697 0.175 ENST00000518742.1
LARP1
La ribonucleoprotein domain family, member 1
chr12_+_53846594 0.175 ENST00000550192.1
PCBP2
poly(rC) binding protein 2
chr19_-_55881741 0.174 ENST00000264563.2
ENST00000590625.1
ENST00000585513.1
IL11


interleukin 11


chr11_-_129872672 0.174 ENST00000531431.1
ENST00000527581.1
PRDM10

PR domain containing 10

chr1_-_151431647 0.173 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
POGZ




pogo transposable element with ZNF domain




chr4_+_129732467 0.172 ENST00000413543.2
PHF17
jade family PHD finger 1
chr11_-_77531752 0.172 ENST00000440064.2
ENST00000528095.1
RSF1

remodeling and spacing factor 1

chr2_-_230786378 0.172 ENST00000430954.1
TRIP12
thyroid hormone receptor interactor 12
chr3_+_184033551 0.172 ENST00000456033.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr6_-_143266297 0.172 ENST00000367603.2
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr2_-_55277654 0.171 ENST00000337526.6
ENST00000317610.7
ENST00000357732.4
RTN4


reticulon 4


chr16_+_30969055 0.170 ENST00000452917.1
SETD1A
SET domain containing 1A
chr10_-_12084770 0.168 ENST00000357604.5
UPF2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr2_+_204193149 0.168 ENST00000422511.2
ABI2
abl-interactor 2
chr1_-_161279749 0.168 ENST00000533357.1
ENST00000360451.6
ENST00000336559.4
MPZ


myelin protein zero


chr12_+_100661156 0.167 ENST00000360820.2
SCYL2
SCY1-like 2 (S. cerevisiae)
chr17_-_58469329 0.166 ENST00000393003.3
USP32
ubiquitin specific peptidase 32
chr11_-_67980744 0.166 ENST00000401547.2
ENST00000453170.1
ENST00000304363.4
SUV420H1


suppressor of variegation 4-20 homolog 1 (Drosophila)


chrX_-_70326455 0.166 ENST00000374251.5
CXorf65
chromosome X open reading frame 65
chr2_+_149402989 0.165 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr8_-_41909496 0.164 ENST00000265713.2
ENST00000406337.1
ENST00000396930.3
ENST00000485568.1
ENST00000426524.1
KAT6A




K(lysine) acetyltransferase 6A




chr19_+_38880695 0.164 ENST00000587947.1
ENST00000338502.4
SPRED3

sprouty-related, EVH1 domain containing 3

chr16_+_9185450 0.164 ENST00000327827.7
C16orf72
chromosome 16 open reading frame 72
chr15_+_38544476 0.163 ENST00000299084.4
SPRED1
sprouty-related, EVH1 domain containing 1
chr2_+_181845843 0.162 ENST00000602710.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr2_-_64881018 0.160 ENST00000313349.3
SERTAD2
SERTA domain containing 2
chr16_+_23765948 0.160 ENST00000300113.2
CHP2
calcineurin-like EF-hand protein 2
chr16_+_2802623 0.159 ENST00000576924.1
ENST00000575009.1
ENST00000576415.1
ENST00000571378.1
SRRM2



serine/arginine repetitive matrix 2



chr1_+_151512775 0.158 ENST00000368849.3
ENST00000392712.3
ENST00000353024.3
ENST00000368848.2
ENST00000538902.1
TUFT1




tuftelin 1




chr1_+_164529004 0.156 ENST00000559240.1
ENST00000367897.1
ENST00000540236.1
ENST00000401534.1
PBX1



pre-B-cell leukemia homeobox 1



chr12_-_120662499 0.156 ENST00000552550.1
PXN
paxillin
chr15_-_56535464 0.156 ENST00000559447.2
ENST00000422057.1
ENST00000317318.6
ENST00000423270.1
RFX7



regulatory factor X, 7



chrX_+_24167828 0.152 ENST00000379188.3
ENST00000419690.1
ENST00000379177.1
ENST00000304543.5
ZFX



zinc finger protein, X-linked



chr11_+_77532233 0.150 ENST00000525409.1
AAMDC
adipogenesis associated, Mth938 domain containing
chr6_+_45390222 0.148 ENST00000359524.5
RUNX2
runt-related transcription factor 2
chr11_-_77531858 0.148 ENST00000360355.2
RSF1
remodeling and spacing factor 1
chr10_+_70091812 0.145 ENST00000265866.7
HNRNPH3
heterogeneous nuclear ribonucleoprotein H3 (2H9)
chr11_+_130184888 0.145 ENST00000602376.1
ENST00000532116.3
ENST00000602310.1
RP11-121M22.1


RP11-121M22.1


chr12_-_57522813 0.143 ENST00000556155.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr14_-_21905395 0.142 ENST00000430710.3
ENST00000553283.1
CHD8

chromodomain helicase DNA binding protein 8

chr2_-_55277692 0.141 ENST00000394611.2
RTN4
reticulon 4
chr14_-_23451467 0.141 ENST00000361265.4
ENST00000555074.1
AJUBA
RP11-298I3.5
ajuba LIM protein
RP11-298I3.5
chr5_-_87980587 0.140 ENST00000509783.1
ENST00000509405.1
ENST00000506978.1
ENST00000509265.1
ENST00000513805.1
LINC00461




long intergenic non-protein coding RNA 461




chr3_+_184032313 0.140 ENST00000392537.2
ENST00000444134.1
ENST00000450424.1
ENST00000421110.1
ENST00000382330.3
ENST00000426123.1
ENST00000350481.5
ENST00000455679.1
ENST00000440448.1
EIF4G1








eukaryotic translation initiation factor 4 gamma, 1








chr2_-_208030647 0.140 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr9_+_35792151 0.139 ENST00000342694.2
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr2_-_61765732 0.138 ENST00000443240.1
ENST00000436018.1
XPO1

exportin 1 (CRM1 homolog, yeast)

chr17_-_7141490 0.138 ENST00000574236.1
ENST00000572789.1
PHF23

PHD finger protein 23

chr15_-_101142362 0.137 ENST00000559577.1
ENST00000561308.1
ENST00000560133.1
ENST00000560941.1
ENST00000559736.1
ENST00000560272.1
LINS





lines homolog (Drosophila)





chr3_+_184032283 0.137 ENST00000346169.2
ENST00000414031.1
EIF4G1

eukaryotic translation initiation factor 4 gamma, 1

chr1_-_211752073 0.136 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr3_-_52002194 0.134 ENST00000466412.1
PCBP4
poly(rC) binding protein 4
chrX_+_70503037 0.134 ENST00000535149.1
NONO
non-POU domain containing, octamer-binding
chr19_-_14629224 0.134 ENST00000254322.2
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr1_-_150208291 0.133 ENST00000533654.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr8_-_101963677 0.133 ENST00000395956.3
ENST00000395953.2
YWHAZ

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta

chr10_+_12391685 0.133 ENST00000378845.1
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr2_-_208030295 0.132 ENST00000458272.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr17_+_65821780 0.131 ENST00000321892.4
ENST00000335221.5
ENST00000306378.6
BPTF


bromodomain PHD finger transcription factor


chr14_-_53619816 0.131 ENST00000323669.5
ENST00000395606.1
ENST00000357758.3
DDHD1


DDHD domain containing 1


chr20_+_34359905 0.131 ENST00000374012.3
ENST00000439301.1
ENST00000339089.6
ENST00000374000.4
PHF20



PHD finger protein 20



chr8_+_61592073 0.131 ENST00000526846.1
CHD7
chromodomain helicase DNA binding protein 7
chr2_+_61108771 0.130 ENST00000394479.3
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr1_-_85156417 0.130 ENST00000422026.1
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr2_-_55277512 0.130 ENST00000402434.2
RTN4
reticulon 4
chr4_+_123747834 0.130 ENST00000264498.3
FGF2
fibroblast growth factor 2 (basic)
chr1_-_167906277 0.130 ENST00000271373.4
MPC2
mitochondrial pyruvate carrier 2
chr4_-_125633876 0.130 ENST00000504087.1
ENST00000515641.1
ANKRD50

ankyrin repeat domain 50

chr6_-_151712673 0.128 ENST00000325144.4
ZBTB2
zinc finger and BTB domain containing 2
chr15_-_43785274 0.128 ENST00000413546.1
TP53BP1
tumor protein p53 binding protein 1
chr4_-_99850243 0.128 ENST00000280892.6
ENST00000511644.1
ENST00000504432.1
ENST00000505992.1
EIF4E



eukaryotic translation initiation factor 4E



chr10_+_21823079 0.127 ENST00000377100.3
ENST00000377072.3
ENST00000446906.2
MLLT10


myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10


chr7_-_127032363 0.126 ENST00000393312.1
ZNF800
zinc finger protein 800
chr19_+_10531150 0.125 ENST00000352831.6
PDE4A
phosphodiesterase 4A, cAMP-specific
chr1_+_16085244 0.125 ENST00000400773.1
FBLIM1
filamin binding LIM protein 1
chr19_+_10563567 0.125 ENST00000344979.3
PDE4A
phosphodiesterase 4A, cAMP-specific
chr2_+_159313452 0.124 ENST00000389757.3
ENST00000389759.3
PKP4

plakophilin 4

chr10_+_70091847 0.124 ENST00000441000.2
ENST00000354695.5
HNRNPH3

heterogeneous nuclear ribonucleoprotein H3 (2H9)

chr9_+_116327326 0.124 ENST00000342620.5
RGS3
regulator of G-protein signaling 3
chr1_+_167905894 0.123 ENST00000367843.3
ENST00000432587.2
ENST00000312263.6
DCAF6


DDB1 and CUL4 associated factor 6


chr3_-_47205457 0.122 ENST00000409792.3
SETD2
SET domain containing 2
chr2_-_208030886 0.122 ENST00000426163.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr9_+_100745615 0.122 ENST00000339399.4
ANP32B
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr2_-_230786679 0.121 ENST00000543084.1
ENST00000343290.5
ENST00000389044.4
ENST00000283943.5
TRIP12



thyroid hormone receptor interactor 12



chr3_+_197464046 0.121 ENST00000428738.1
FYTTD1
forty-two-three domain containing 1
chr11_-_122933043 0.121 ENST00000534624.1
ENST00000453788.2
ENST00000527387.1
HSPA8


heat shock 70kDa protein 8


chr12_+_69004805 0.119 ENST00000541216.1
RAP1B
RAP1B, member of RAS oncogene family
chr1_+_178694408 0.119 ENST00000324778.5
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr12_-_111180644 0.118 ENST00000551676.1
ENST00000550991.1
ENST00000335007.5
ENST00000340766.5
PPP1CC



protein phosphatase 1, catalytic subunit, gamma isozyme



chr9_+_112887772 0.117 ENST00000259318.7
AKAP2
A kinase (PRKA) anchor protein 2
chr2_-_61697862 0.116 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr2_-_61765315 0.116 ENST00000406957.1
ENST00000401558.2
XPO1

exportin 1 (CRM1 homolog, yeast)

chr1_-_111746966 0.116 ENST00000369752.5
DENND2D
DENN/MADD domain containing 2D
chrX_+_12993336 0.115 ENST00000380635.1
TMSB4X
thymosin beta 4, X-linked
chr9_+_33524240 0.115 ENST00000290943.6
ANKRD18B
ankyrin repeat domain 18B
chr3_-_42846021 0.114 ENST00000321331.7
HIGD1A
HIG1 hypoxia inducible domain family, member 1A
chr2_-_145277569 0.114 ENST00000303660.4
ZEB2
zinc finger E-box binding homeobox 2
chr18_+_29672573 0.113 ENST00000578107.1
ENST00000257190.5
ENST00000580499.1
RNF138


ring finger protein 138, E3 ubiquitin protein ligase


chr1_+_27022839 0.112 ENST00000457599.2
ARID1A
AT rich interactive domain 1A (SWI-like)
chr15_-_101142401 0.112 ENST00000314742.8
LINS
lines homolog (Drosophila)
chr12_-_57824739 0.111 ENST00000347140.3
ENST00000402412.1
R3HDM2

R3H domain containing 2

chr3_+_184032419 0.111 ENST00000352767.3
ENST00000427141.2
EIF4G1

eukaryotic translation initiation factor 4 gamma, 1

chrX_-_118739835 0.110 ENST00000542113.1
ENST00000304449.5
NKRF

NFKB repressing factor

chr15_-_69113218 0.110 ENST00000560303.1
ENST00000465139.2
ANP32A

acidic (leucine-rich) nuclear phosphoprotein 32 family, member A

chr17_-_27278304 0.110 ENST00000577226.1
PHF12
PHD finger protein 12
chr8_+_26149007 0.110 ENST00000380737.3
ENST00000524169.1
PPP2R2A

protein phosphatase 2, regulatory subunit B, alpha

chr4_+_123747979 0.110 ENST00000608478.1
FGF2
fibroblast growth factor 2 (basic)
chr10_+_98592009 0.109 ENST00000540664.1
ENST00000371103.3
LCOR

ligand dependent nuclear receptor corepressor

chr2_-_174828892 0.109 ENST00000418194.2
SP3
Sp3 transcription factor
chr15_+_100106244 0.109 ENST00000557942.1
MEF2A
myocyte enhancer factor 2A
chr16_+_50187556 0.109 ENST00000561678.1
ENST00000357464.3
PAPD5

PAP associated domain containing 5


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0002605 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605)
0.1 1.4 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.4 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.7 GO:0072553 terminal button organization(GO:0072553)
0.1 0.6 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.2 GO:0042660 positive regulation of cell fate specification(GO:0042660)
0.1 1.1 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.3 GO:0007499 ectoderm and mesoderm interaction(GO:0007499) female genitalia morphogenesis(GO:0048807)
0.1 0.6 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 0.4 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.1 0.3 GO:0048389 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) deltoid tuberosity development(GO:0035993) intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) pattern specification involved in mesonephros development(GO:0061227) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.4 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
0.1 0.6 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.2 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.2 GO:0001172 transcription, RNA-templated(GO:0001172)
0.1 0.2 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.0 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.6 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 0.2 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.0 0.2 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.1 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.0 0.1 GO:0006848 pyruvate transport(GO:0006848) mitochondrial pyruvate transport(GO:0006850) pyruvate transmembrane transport(GO:1901475) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.1 GO:0043633 polyadenylation-dependent RNA catabolic process(GO:0043633) polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.0 0.1 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.0 0.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.1 GO:0040040 thermosensory behavior(GO:0040040)
0.0 0.1 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.2 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.2 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.2 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.7 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.2 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.1 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.0 0.6 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.2 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.2 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 1.6 GO:0043486 histone exchange(GO:0043486)
0.0 1.9 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.3 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.2 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.1 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.1 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.3 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.2 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.0 0.5 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.1 GO:2000977 inhibition of neuroepithelial cell differentiation(GO:0002085) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974) regulation of forebrain neuron differentiation(GO:2000977)
0.0 0.1 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.0 0.1 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.1 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.2 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.2 GO:0060318 regulation of definitive erythrocyte differentiation(GO:0010724) definitive erythrocyte differentiation(GO:0060318)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) positive regulation of connective tissue replacement(GO:1905205)
0.0 0.1 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.2 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.2 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0060948 coronary vein morphogenesis(GO:0003169) primitive erythrocyte differentiation(GO:0060319) cardiac vascular smooth muscle cell development(GO:0060948) regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.0 0.2 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.6 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.0 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.1 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 0.1 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.3 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.1 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 1.1 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.2 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.1 GO:0048680 negative regulation of heart rate(GO:0010459) positive regulation of axon regeneration(GO:0048680)
0.0 0.4 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.2 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.0 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.0 0.2 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.1 GO:2000782 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.1 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.1 GO:0035565 regulation of pronephros size(GO:0035565)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.0 GO:0035283 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.1 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 0.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.3 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.3 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.0 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.0 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.1 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.0 GO:0010940 positive regulation of necrotic cell death(GO:0010940)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.3 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.1 0.6 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.3 GO:0031213 RSF complex(GO:0031213)
0.1 0.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 1.4 GO:0031209 SCAR complex(GO:0031209)
0.1 1.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 1.1 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.7 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.5 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 0.4 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0075341 host cell PML body(GO:0075341)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 0.5 GO:0033643 host cell part(GO:0033643)
0.0 0.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664) beta-catenin-TCF complex(GO:1990907)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.8 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.0 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.4 GO:0097346 INO80-type complex(GO:0097346)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.0 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.3 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.3 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.4 GO:0070051 fibrinogen binding(GO:0070051) collagen V binding(GO:0070052)
0.1 1.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.6 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.2 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.1 0.5 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 1.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.2 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.0 0.0 GO:0045142 triplex DNA binding(GO:0045142)
0.0 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 1.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.6 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.1 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.2 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.2 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.1 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.1 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.6 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.1 GO:0019770 IgG receptor activity(GO:0019770)
0.0 1.4 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.0 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.6 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 1.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.0 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 1.1 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.0 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.3 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.0 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.0 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.0 0.0 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.1 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.0 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 1.4 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.1 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 0.1 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 0.3 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.2 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.0 1.3 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 1.4 PID_LKB1_PATHWAY LKB1 signaling events
0.0 1.8 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 1.3 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.7 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.6 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.2 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.7 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.6 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway