Motif ID: ZNF143

Z-value: 1.433


Transcription factors associated with ZNF143:

Gene SymbolEntrez IDGene Name
ZNF143 ENSG00000166478.5 ZNF143

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZNF143hg19_v2_chr11_+_9482551_9482604-0.655.7e-02Click!


Activity profile for motif ZNF143.

activity profile for motif ZNF143


Sorted Z-values histogram for motif ZNF143

Sorted Z-values for motif ZNF143



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF143

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_31736132 1.426 ENST00000429785.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr4_-_1857954 0.997 ENST00000302787.2
LETM1
leucine zipper-EF-hand containing transmembrane protein 1
chr7_+_112090483 0.986 ENST00000403825.3
ENST00000429071.1
IFRD1

interferon-related developmental regulator 1

chr12_+_53895052 0.895 ENST00000552857.1
TARBP2
TAR (HIV-1) RNA binding protein 2
chr12_-_122985494 0.891 ENST00000336229.4
ZCCHC8
zinc finger, CCHC domain containing 8
chr20_-_30795511 0.839 ENST00000246229.4
PLAGL2
pleiomorphic adenoma gene-like 2
chr19_+_50145328 0.796 ENST00000360565.3
SCAF1
SR-related CTD-associated factor 1
chr13_-_31736478 0.790 ENST00000445273.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr12_-_122985067 0.789 ENST00000540586.1
ENST00000543897.1
ZCCHC8

zinc finger, CCHC domain containing 8

chr16_+_577697 0.765 ENST00000562370.1
ENST00000568988.1
ENST00000219611.2
CAPN15


calpain 15


chr4_+_140222609 0.742 ENST00000296543.5
ENST00000398947.1
NAA15

N(alpha)-acetyltransferase 15, NatA auxiliary subunit

chr13_-_31736027 0.733 ENST00000380406.5
ENST00000320027.5
ENST00000380405.4
HSPH1


heat shock 105kDa/110kDa protein 1


chr7_+_65579799 0.709 ENST00000431089.2
ENST00000398684.2
ENST00000338592.5
CRCP


CGRP receptor component


chr2_-_26205550 0.702 ENST00000405914.1
KIF3C
kinesin family member 3C
chr2_-_26205340 0.692 ENST00000264712.3
KIF3C
kinesin family member 3C
chr19_-_5791215 0.669 ENST00000320699.8
ENST00000309061.7
DUS3L

dihydrouridine synthase 3-like (S. cerevisiae)

chr16_+_2802623 0.654 ENST00000576924.1
ENST00000575009.1
ENST00000576415.1
ENST00000571378.1
SRRM2



serine/arginine repetitive matrix 2



chr17_-_1619491 0.644 ENST00000570416.1
ENST00000575626.1
ENST00000610106.1
ENST00000608198.1
ENST00000609442.1
ENST00000334146.3
ENST00000576489.1
ENST00000608245.1
ENST00000609398.1
ENST00000608913.1
ENST00000574016.1
ENST00000571091.1
ENST00000573127.1
ENST00000609990.1
ENST00000576749.1
MIR22HG














MIR22 host gene (non-protein coding)














chr19_+_28284803 0.627 ENST00000586220.1
ENST00000588784.1
ENST00000591549.1
ENST00000585827.1
ENST00000588636.1
ENST00000587188.1
CTC-459F4.3





CTC-459F4.3





chr17_-_1619535 0.620 ENST00000573075.1
ENST00000574306.1
MIR22HG

MIR22 host gene (non-protein coding)

chr12_+_56498312 0.617 ENST00000552766.1
PA2G4
proliferation-associated 2G4, 38kDa
chr19_+_28284357 0.612 ENST00000588122.1
ENST00000586784.1
ENST00000590628.1
ENST00000592404.1
ENST00000588318.1
ENST00000585917.1
CTC-459F4.3





CTC-459F4.3





chr1_+_19578033 0.605 ENST00000330263.4
MRTO4
mRNA turnover 4 homolog (S. cerevisiae)
chr19_+_56915668 0.600 ENST00000333201.9
ENST00000391778.3
ZNF583

zinc finger protein 583

chrX_+_37545012 0.595 ENST00000378616.3
XK
X-linked Kx blood group (McLeod syndrome)
chr4_-_2965052 0.576 ENST00000398071.4
ENST00000502735.1
ENST00000314262.6
ENST00000416614.2
NOP14



NOP14 nucleolar protein



chr8_-_67525524 0.568 ENST00000517885.1
MYBL1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr18_+_77439775 0.563 ENST00000299543.7
ENST00000075430.7
CTDP1

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1

chr13_+_25875662 0.555 ENST00000381736.3
ENST00000463407.1
ENST00000381718.3
NUPL1


nucleoporin like 1


chr13_+_25875785 0.534 ENST00000381747.3
NUPL1
nucleoporin like 1
chr17_-_1619568 0.529 ENST00000571595.1
MIR22HG
MIR22 host gene (non-protein coding)
chr8_+_67341239 0.529 ENST00000320270.2
RRS1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr17_-_76356148 0.525 ENST00000587578.1
ENST00000330871.2
SOCS3

suppressor of cytokine signaling 3

chr8_-_67525473 0.520 ENST00000522677.3
MYBL1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr6_-_116989916 0.519 ENST00000368576.3
ENST00000368573.1
ZUFSP

zinc finger with UFM1-specific peptidase domain

chr16_+_8891670 0.516 ENST00000268261.4
ENST00000539622.1
ENST00000569958.1
ENST00000537352.1
PMM2



phosphomannomutase 2



chr4_+_186347388 0.502 ENST00000511138.1
ENST00000511581.1
C4orf47

chromosome 4 open reading frame 47

chr22_-_30987849 0.501 ENST00000402284.3
ENST00000354694.7
PES1

pescadillo ribosomal biogenesis factor 1

chr16_-_69419473 0.495 ENST00000566750.1
TERF2
telomeric repeat binding factor 2
chr12_+_53895364 0.493 ENST00000552817.1
ENST00000394357.2
TARBP2

TAR (HIV-1) RNA binding protein 2

chr1_-_54304212 0.492 ENST00000540001.1
NDC1
NDC1 transmembrane nucleoporin
chr1_-_54303949 0.489 ENST00000234725.8
NDC1
NDC1 transmembrane nucleoporin
chr13_-_50367057 0.480 ENST00000261667.3
KPNA3
karyopherin alpha 3 (importin alpha 4)
chr20_+_30795664 0.478 ENST00000375749.3
ENST00000375730.3
ENST00000539210.1
POFUT1


protein O-fucosyltransferase 1


chr22_-_30987837 0.474 ENST00000335214.6
PES1
pescadillo ribosomal biogenesis factor 1
chr16_+_2802316 0.469 ENST00000301740.8
SRRM2
serine/arginine repetitive matrix 2
chr22_-_31503490 0.469 ENST00000400299.2
SELM
Selenoprotein M
chr16_-_75285380 0.468 ENST00000393420.6
ENST00000162330.5
BCAR1

breast cancer anti-estrogen resistance 1

chr16_-_279405 0.467 ENST00000430864.1
ENST00000293872.8
ENST00000337351.4
ENST00000397783.1
LUC7L



LUC7-like (S. cerevisiae)



chr2_+_25016282 0.465 ENST00000260662.1
CENPO
centromere protein O
chr12_+_107168418 0.449 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
RIC8B




RIC8 guanine nucleotide exchange factor B




chr11_+_2421718 0.441 ENST00000380996.5
ENST00000333256.6
ENST00000380992.1
ENST00000437110.1
ENST00000435795.1
TSSC4




tumor suppressing subtransferable candidate 4




chr19_-_56826157 0.440 ENST00000592509.1
ENST00000592679.1
ENST00000588442.1
ENST00000593106.1
ENST00000587492.1
ENST00000254165.3
ZSCAN5A





zinc finger and SCAN domain containing 5A





chr9_-_130712995 0.439 ENST00000373084.4
FAM102A
family with sequence similarity 102, member A
chr12_-_49523896 0.439 ENST00000549870.1
TUBA1B
tubulin, alpha 1b
chr8_-_145018905 0.439 ENST00000398774.2
PLEC
plectin
chr16_-_18937726 0.438 ENST00000389467.3
ENST00000446231.2
SMG1

SMG1 phosphatidylinositol 3-kinase-related kinase

chr11_-_65626753 0.437 ENST00000526975.1
ENST00000531413.1
CFL1

cofilin 1 (non-muscle)

chr11_+_117198801 0.433 ENST00000527609.1
ENST00000533570.1
CEP164

centrosomal protein 164kDa

chr9_-_34048873 0.428 ENST00000449054.1
ENST00000379239.4
ENST00000539807.1
ENST00000379238.1
ENST00000418786.2
ENST00000360802.1
ENST00000412543.1
UBAP2






ubiquitin associated protein 2






chr2_-_148778323 0.427 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
ORC4



origin recognition complex, subunit 4



chr3_+_67048721 0.426 ENST00000295568.4
ENST00000484414.1
ENST00000460576.1
ENST00000417314.2
KBTBD8



kelch repeat and BTB (POZ) domain containing 8



chr3_+_196466710 0.424 ENST00000327134.3
PAK2
p21 protein (Cdc42/Rac)-activated kinase 2
chr6_-_5004241 0.419 ENST00000319533.5
ENST00000380051.2
RPP40

ribonuclease P/MRP 40kDa subunit

chr1_-_26633480 0.415 ENST00000450041.1
UBXN11
UBX domain protein 11
chr5_-_175815565 0.410 ENST00000509257.1
ENST00000507413.1
ENST00000510123.1
NOP16


NOP16 nucleolar protein


chr19_+_37862054 0.403 ENST00000483919.1
ENST00000588911.1
ENST00000436120.2
ENST00000587349.1
ZNF527



zinc finger protein 527



chr19_-_36019123 0.401 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
SBSN


suprabasin


chr20_+_55966444 0.400 ENST00000356208.5
ENST00000440234.2
RBM38

RNA binding motif protein 38

chr16_+_23690138 0.398 ENST00000300093.4
PLK1
polo-like kinase 1
chr1_-_184723701 0.395 ENST00000367512.3
EDEM3
ER degradation enhancer, mannosidase alpha-like 3
chr11_+_66025274 0.395 ENST00000461611.1
KLC2
kinesin light chain 2
chr11_-_64545941 0.394 ENST00000377387.1
SF1
splicing factor 1
chr5_-_171433548 0.393 ENST00000517395.1
FBXW11
F-box and WD repeat domain containing 11
chr11_+_57425209 0.385 ENST00000533905.1
ENST00000525602.1
ENST00000302731.4
CLP1


cleavage and polyadenylation factor I subunit 1


chr11_-_66112555 0.380 ENST00000425825.2
ENST00000359957.3
BRMS1

breast cancer metastasis suppressor 1

chr6_+_30312908 0.378 ENST00000433076.2
ENST00000442966.2
ENST00000428040.2
ENST00000436442.2
RPP21



ribonuclease P/MRP 21kDa subunit



chr11_-_72385437 0.377 ENST00000418754.2
ENST00000542969.2
ENST00000334456.5
PDE2A


phosphodiesterase 2A, cGMP-stimulated


chr2_+_25015968 0.377 ENST00000380834.2
ENST00000473706.1
CENPO

centromere protein O

chr21_-_33104367 0.375 ENST00000286835.7
ENST00000399804.1
SCAF4

SR-related CTD-associated factor 4

chr1_-_54303934 0.375 ENST00000537333.1
NDC1
NDC1 transmembrane nucleoporin
chr20_+_32399093 0.374 ENST00000217402.2
CHMP4B
charged multivesicular body protein 4B
chr1_-_10532531 0.370 ENST00000377036.2
ENST00000377038.3
DFFA

DNA fragmentation factor, 45kDa, alpha polypeptide

chr8_-_101734907 0.370 ENST00000318607.5
ENST00000521865.1
ENST00000520804.1
ENST00000522720.1
ENST00000521067.1
PABPC1




poly(A) binding protein, cytoplasmic 1




chr14_+_36295638 0.367 ENST00000543183.1
BRMS1L
breast cancer metastasis-suppressor 1-like
chr21_-_33104260 0.362 ENST00000434667.3
SCAF4
SR-related CTD-associated factor 4
chr12_+_12966250 0.360 ENST00000352940.4
ENST00000358007.3
ENST00000544400.1
DDX47


DEAD (Asp-Glu-Ala-Asp) box polypeptide 47


chr7_-_148787768 0.358 ENST00000491431.1
ENST00000451334.3
ENST00000316286.9
ZNF786


zinc finger protein 786


chr3_+_151986709 0.356 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
MBNL1



muscleblind-like splicing regulator 1



chr10_-_105110890 0.352 ENST00000369847.3
PCGF6
polycomb group ring finger 6
chr16_-_12009833 0.351 ENST00000420576.2
GSPT1
G1 to S phase transition 1
chr1_-_38157877 0.351 ENST00000477060.1
ENST00000491981.1
ENST00000488137.1
C1orf109


chromosome 1 open reading frame 109


chr11_+_61891445 0.350 ENST00000394818.3
ENST00000533896.1
ENST00000278849.4
INCENP


inner centromere protein antigens 135/155kDa


chr17_-_5323480 0.348 ENST00000573584.1
NUP88
nucleoporin 88kDa
chr10_-_105110831 0.348 ENST00000337211.4
PCGF6
polycomb group ring finger 6
chr1_-_156571254 0.348 ENST00000438976.2
ENST00000334588.7
ENST00000368232.4
ENST00000415314.2
GPATCH4



G patch domain containing 4



chr6_+_160148593 0.347 ENST00000337387.4
WTAP
Wilms tumor 1 associated protein
chr5_-_171433579 0.347 ENST00000265094.5
ENST00000393802.2
FBXW11

F-box and WD repeat domain containing 11

chr12_-_6961050 0.346 ENST00000538862.2
CDCA3
cell division cycle associated 3
chr9_+_116173000 0.345 ENST00000288462.4
C9orf43
chromosome 9 open reading frame 43
chr1_+_156052354 0.344 ENST00000368301.2
LMNA
lamin A/C
chr11_-_65626797 0.338 ENST00000525451.2
CFL1
cofilin 1 (non-muscle)
chr19_-_50169064 0.336 ENST00000593337.1
ENST00000598808.1
ENST00000600453.1
ENST00000593818.1
ENST00000597198.1
ENST00000601809.1
ENST00000377139.3
IRF3






interferon regulatory factor 3






chr7_+_99214559 0.336 ENST00000394152.2
ENST00000431485.2
ZSCAN25

zinc finger and SCAN domain containing 25

chr19_-_50168962 0.336 ENST00000599223.1
ENST00000593922.1
ENST00000600022.1
ENST00000596765.1
ENST00000599144.1
ENST00000596822.1
ENST00000598108.1
ENST00000601373.1
ENST00000595034.1
ENST00000601291.1
IRF3









interferon regulatory factor 3









chr9_+_116172958 0.335 ENST00000374165.1
C9orf43
chromosome 9 open reading frame 43
chr14_+_36295504 0.334 ENST00000216807.7
BRMS1L
breast cancer metastasis-suppressor 1-like
chr18_+_9102669 0.330 ENST00000497577.2
NDUFV2
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
chr19_-_37958086 0.329 ENST00000592490.1
ENST00000392149.2
ZNF569

zinc finger protein 569

chr19_-_38714847 0.329 ENST00000420980.2
ENST00000355526.4
DPF1

D4, zinc and double PHD fingers family 1

chr1_+_156737292 0.328 ENST00000271526.4
ENST00000353233.3
PRCC

papillary renal cell carcinoma (translocation-associated)

chr14_-_23398565 0.325 ENST00000397440.4
ENST00000538452.1
ENST00000421938.2
ENST00000554867.1
ENST00000556616.1
ENST00000216350.8
ENST00000553550.1
ENST00000397441.2
ENST00000553897.1
PRMT5








protein arginine methyltransferase 5








chr2_+_219187871 0.324 ENST00000258362.3
PNKD
paroxysmal nonkinesigenic dyskinesia
chr15_+_41221536 0.317 ENST00000249749.5
DLL4
delta-like 4 (Drosophila)
chr16_-_12009735 0.316 ENST00000439887.2
ENST00000434724.2
GSPT1

G1 to S phase transition 1

chr1_-_53163992 0.315 ENST00000371538.3
SELRC1
cytochrome c oxidase assembly factor 7
chr1_-_184723942 0.315 ENST00000318130.8
EDEM3
ER degradation enhancer, mannosidase alpha-like 3
chr2_+_149402553 0.313 ENST00000258484.6
ENST00000409654.1
EPC2

enhancer of polycomb homolog 2 (Drosophila)

chr13_+_50656307 0.313 ENST00000378180.4
DLEU1
deleted in lymphocytic leukemia 1 (non-protein coding)
chr8_-_74884482 0.313 ENST00000520242.1
ENST00000519082.1
TCEB1

transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)

chr11_+_66025167 0.312 ENST00000394067.2
ENST00000316924.5
ENST00000421552.1
ENST00000394078.1
KLC2



kinesin light chain 2



chr2_-_148778258 0.310 ENST00000392857.5
ENST00000457954.1
ENST00000392858.1
ENST00000542387.1
ORC4



origin recognition complex, subunit 4



chr12_+_32832203 0.310 ENST00000553257.1
ENST00000549701.1
ENST00000358214.5
ENST00000266481.6
ENST00000551476.1
ENST00000550154.1
ENST00000547312.1
ENST00000414834.2
ENST00000381000.4
ENST00000548750.1
DNM1L









dynamin 1-like









chr16_-_18937480 0.308 ENST00000532700.2
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr19_-_42746714 0.308 ENST00000222330.3
GSK3A
glycogen synthase kinase 3 alpha
chr5_+_137673200 0.308 ENST00000434981.2
FAM53C
family with sequence similarity 53, member C
chr19_-_6424283 0.307 ENST00000595258.1
ENST00000595548.1
KHSRP

KH-type splicing regulatory protein

chr5_+_149737202 0.306 ENST00000451292.1
ENST00000377797.3
ENST00000445265.2
ENST00000323668.7
ENST00000439160.2
ENST00000394269.3
ENST00000427724.2
ENST00000504761.2
ENST00000513346.1
ENST00000515516.1
TCOF1









Treacher Collins-Franceschetti syndrome 1









chrX_-_9002168 0.306 ENST00000327220.5
FAM9B
family with sequence similarity 9, member B
chr19_+_56653064 0.305 ENST00000593100.1
ZNF444
zinc finger protein 444
chr11_+_117198545 0.303 ENST00000533153.1
ENST00000278935.3
ENST00000525416.1
CEP164


centrosomal protein 164kDa


chr12_-_66524482 0.302 ENST00000446587.2
ENST00000266604.2
LLPH

LLP homolog, long-term synaptic facilitation (Aplysia)

chr16_+_4475806 0.298 ENST00000262375.6
ENST00000355296.4
ENST00000431375.2
ENST00000574895.1
DNAJA3



DnaJ (Hsp40) homolog, subfamily A, member 3



chr11_+_130184888 0.297 ENST00000602376.1
ENST00000532116.3
ENST00000602310.1
RP11-121M22.1


RP11-121M22.1


chr1_+_38158090 0.297 ENST00000373055.1
ENST00000327331.2
CDCA8

cell division cycle associated 8

chr1_-_211752073 0.295 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr16_-_4664860 0.294 ENST00000587615.1
ENST00000587649.1
ENST00000590965.1
ENST00000591401.1
ENST00000283474.7
UBALD1




UBA-like domain containing 1




chr22_+_50624323 0.293 ENST00000380909.4
ENST00000303434.4
TRABD

TraB domain containing

chr19_-_1021113 0.291 ENST00000333175.5
ENST00000356663.3
TMEM259

transmembrane protein 259

chr11_+_208815 0.289 ENST00000530889.1
RIC8A
RIC8 guanine nucleotide exchange factor A
chr11_-_64546202 0.289 ENST00000377390.3
ENST00000227503.9
ENST00000377394.3
ENST00000422298.2
ENST00000334944.5
SF1




splicing factor 1




chr2_+_97202480 0.288 ENST00000357485.3
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr19_+_56652686 0.285 ENST00000592949.1
ZNF444
zinc finger protein 444
chr16_+_83986827 0.285 ENST00000393306.1
ENST00000565123.1
OSGIN1

oxidative stress induced growth inhibitor 1

chr15_+_41913690 0.284 ENST00000563576.1
MGA
MGA, MAX dimerization protein
chr11_+_66024737 0.283 ENST00000531240.1
ENST00000417856.1
KLC2

kinesin light chain 2

chr5_+_137673945 0.281 ENST00000513056.1
ENST00000511276.1
FAM53C

family with sequence similarity 53, member C

chr3_+_49977894 0.280 ENST00000433811.1
RBM6
RNA binding motif protein 6
chr2_-_202316169 0.279 ENST00000430254.1
TRAK2
trafficking protein, kinesin binding 2
chr1_-_213189108 0.279 ENST00000535388.1
ANGEL2
angel homolog 2 (Drosophila)
chr18_-_29264669 0.279 ENST00000306851.5
B4GALT6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr5_-_171433819 0.276 ENST00000296933.6
FBXW11
F-box and WD repeat domain containing 11
chr11_+_94706804 0.276 ENST00000335080.5
KDM4D
lysine (K)-specific demethylase 4D
chr9_-_135545380 0.271 ENST00000544003.1
DDX31
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr12_+_22778009 0.271 ENST00000266517.4
ENST00000335148.3
ETNK1

ethanolamine kinase 1

chr1_-_26633067 0.270 ENST00000421827.2
ENST00000374215.1
ENST00000374223.1
ENST00000357089.4
ENST00000535108.1
ENST00000314675.7
ENST00000436301.2
ENST00000423664.1
ENST00000374221.3
UBXN11








UBX domain protein 11








chr1_+_168195188 0.269 ENST00000367829.1
SFT2D2
SFT2 domain containing 2
chr17_-_77005860 0.268 ENST00000591773.1
ENST00000588611.1
ENST00000586916.2
ENST00000592033.1
ENST00000588075.1
ENST00000302345.2
ENST00000591811.1
CANT1






calcium activated nucleotidase 1






chr19_+_50169081 0.265 ENST00000246784.3
BCL2L12
BCL2-like 12 (proline rich)
chr19_-_37958318 0.265 ENST00000316950.6
ENST00000591710.1
ZNF569

zinc finger protein 569

chr1_-_213189079 0.264 ENST00000540642.1
ANGEL2
angel homolog 2 (Drosophila)
chr3_-_9005118 0.264 ENST00000264926.2
RAD18
RAD18 homolog (S. cerevisiae)
chr1_-_244615425 0.263 ENST00000366535.3
ADSS
adenylosuccinate synthase
chrX_+_48334549 0.263 ENST00000019019.2
ENST00000348411.2
ENST00000396894.4
FTSJ1


FtsJ RNA methyltransferase homolog 1 (E. coli)


chr12_+_27677085 0.262 ENST00000545334.1
ENST00000540114.1
ENST00000537927.1
ENST00000318304.8
ENST00000535047.1
ENST00000542629.1
ENST00000228425.6
PPFIBP1






PTPRF interacting protein, binding protein 1 (liprin beta 1)






chr19_-_55770311 0.261 ENST00000412770.2
PPP6R1
protein phosphatase 6, regulatory subunit 1
chr5_+_74807581 0.260 ENST00000241436.4
ENST00000352007.5
POLK

polymerase (DNA directed) kappa

chr19_-_38720294 0.259 ENST00000412732.1
ENST00000456296.1
DPF1

D4, zinc and double PHD fingers family 1

chr16_+_56764017 0.257 ENST00000308159.5
ENST00000563858.1
ENST00000566315.1
ENST00000569842.1
ENST00000569863.1
NUP93




nucleoporin 93kDa




chr12_+_88429223 0.257 ENST00000356891.3
C12orf29
chromosome 12 open reading frame 29
chr2_+_239229129 0.256 ENST00000391994.2
TRAF3IP1
TNF receptor-associated factor 3 interacting protein 1
chr11_+_33037401 0.256 ENST00000241051.3
DEPDC7
DEP domain containing 7
chr19_+_4791722 0.255 ENST00000269856.3
FEM1A
fem-1 homolog a (C. elegans)
chr16_+_4666475 0.255 ENST00000591895.1
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr11_+_94706973 0.253 ENST00000536741.1
KDM4D
lysine (K)-specific demethylase 4D
chr9_+_131038425 0.253 ENST00000320188.5
ENST00000608796.1
ENST00000419867.2
ENST00000418976.1
SWI5



SWI5 recombination repair homolog (yeast)



chr1_+_28157273 0.252 ENST00000311772.5
ENST00000236412.7
ENST00000373931.4
PPP1R8


protein phosphatase 1, regulatory subunit 8


chr1_-_213188772 0.251 ENST00000544555.1
ANGEL2
angel homolog 2 (Drosophila)
chr19_-_45579762 0.251 ENST00000303809.2
ZNF296
zinc finger protein 296
chr19_-_4182497 0.251 ENST00000597896.1
SIRT6
sirtuin 6
chr1_+_33938236 0.251 ENST00000361328.3
ENST00000373413.2
ZSCAN20

zinc finger and SCAN domain containing 20

chr3_-_50396978 0.246 ENST00000266025.3
TMEM115
transmembrane protein 115
chr12_+_22778116 0.246 ENST00000538218.1
ETNK1
ethanolamine kinase 1
chr2_-_73053126 0.245 ENST00000272427.6
ENST00000410104.1
EXOC6B

exocyst complex component 6B

chr19_-_45982076 0.244 ENST00000423698.2
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr19_-_6424783 0.243 ENST00000398148.3
KHSRP
KH-type splicing regulatory protein
chr12_+_32832134 0.243 ENST00000452533.2
DNM1L
dynamin 1-like
chr8_+_38239882 0.242 ENST00000607047.1
RP11-350N15.5
RP11-350N15.5
chr13_-_79979919 0.241 ENST00000267229.7
RBM26
RNA binding motif protein 26
chr1_+_32645269 0.241 ENST00000373610.3
TXLNA
taxilin alpha
chr5_-_61699698 0.240 ENST00000506390.1
ENST00000199320.4
DIMT1

DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)

chr7_+_107384579 0.239 ENST00000222597.2
ENST00000415884.2
CBLL1

Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase

chr19_+_50879705 0.238 ENST00000598168.1
ENST00000411902.2
ENST00000253727.5
ENST00000597790.1
ENST00000597130.1
ENST00000599105.1
NR1H2





nuclear receptor subfamily 1, group H, member 2





chr1_+_45805728 0.237 ENST00000539779.1
TOE1
target of EGR1, member 1 (nuclear)
chr13_-_79979952 0.236 ENST00000438724.1
RBM26
RNA binding motif protein 26
chr3_+_135741576 0.235 ENST00000334546.2
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr15_+_44829334 0.235 ENST00000535391.1
EIF3J
eukaryotic translation initiation factor 3, subunit J
chr11_+_33037652 0.234 ENST00000311388.3
DEPDC7
DEP domain containing 7
chr7_-_148823387 0.233 ENST00000483014.1
ENST00000378061.2
ZNF425

zinc finger protein 425

chr19_+_50169216 0.232 ENST00000594157.1
ENST00000600947.1
ENST00000598306.1
BCL2L12


BCL2-like 12 (proline rich)



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0071790 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.4 2.9 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.3 2.0 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.2 0.7 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.2 0.6 GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.2 0.6 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.2 0.5 GO:1990619 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) histone H3-K9 deacetylation(GO:1990619)
0.1 0.4 GO:1901340 negative regulation of store-operated calcium channel activity(GO:1901340)
0.1 0.6 GO:0031133 regulation of axon diameter(GO:0031133)
0.1 0.6 GO:1903517 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.1 1.0 GO:2000782 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.1 0.5 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.4 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.1 1.0 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.5 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.1 0.3 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.3 GO:0006258 UDP-glucose catabolic process(GO:0006258) positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1 0.4 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.1 0.3 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.1 0.9 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.6 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 0.7 GO:0097466 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.1 0.6 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 0.7 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.1 0.8 GO:0034378 chylomicron assembly(GO:0034378)
0.1 1.0 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.2 GO:0090340 positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of pancreatic juice secretion(GO:0090187) positive regulation of secretion of lysosomal enzymes(GO:0090340)
0.1 1.0 GO:0034214 protein hexamerization(GO:0034214)
0.1 0.2 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.1 0.2 GO:0006481 C-terminal protein methylation(GO:0006481)
0.1 0.2 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.1 0.4 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.8 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.3 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 0.2 GO:2001037 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.1 0.4 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.4 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.7 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.1 0.4 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.1 0.3 GO:0031291 Ran protein signal transduction(GO:0031291)
0.1 0.4 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 0.4 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653) positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1 0.9 GO:0039530 MDA-5 signaling pathway(GO:0039530)
0.1 0.2 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.1 0.7 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.3 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.1 0.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.4 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.4 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 0.3 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.4 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.6 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 1.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.7 GO:0014029 neural crest formation(GO:0014029)
0.0 0.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.3 GO:0060161 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195) positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0 0.1 GO:0032618 interleukin-15 production(GO:0032618)
0.0 0.2 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.0 0.2 GO:0001828 inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.9 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.3 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.5 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.2 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.1 GO:0006429 leucyl-tRNA aminoacylation(GO:0006429)
0.0 0.5 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.2 GO:0035397 helper T cell enhancement of adaptive immune response(GO:0035397)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.6 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.3 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055) ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.2 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.2 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
0.0 0.5 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.4 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.3 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.4 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 1.0 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.4 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:1901291 negative regulation of double-strand break repair via single-strand annealing(GO:1901291)
0.0 0.4 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.2 GO:0006710 androgen catabolic process(GO:0006710)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.3 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.1 GO:0030866 cortical cytoskeleton organization(GO:0030865) cortical actin cytoskeleton organization(GO:0030866)
0.0 0.5 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.3 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.2 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.3 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.5 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 1.1 GO:0071174 mitotic spindle checkpoint(GO:0071174)
0.0 0.2 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0072658 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.5 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.2 GO:0052055 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) negative regulation by host of symbiont molecular function(GO:0052405) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.3 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 2.9 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) protein K29-linked ubiquitination(GO:0035519)
0.0 0.1 GO:1903788 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.3 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.1 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.3 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.0 0.1 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.0 0.7 GO:0035729 cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0 0.2 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.1 GO:0055099 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) response to high density lipoprotein particle(GO:0055099)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0 0.1 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.0 0.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.2 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.1 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.2 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.3 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.0 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.2 GO:0090656 t-circle formation(GO:0090656)
0.0 0.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0015783 GDP-fucose transport(GO:0015783) UDP-N-acetylglucosamine transport(GO:0015788) purine nucleotide-sugar transport(GO:0036079) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.2 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.3 GO:0016246 RNA interference(GO:0016246)
0.0 0.1 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.0 0.2 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.5 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.1 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.1 GO:0016598 protein arginylation(GO:0016598)
0.0 0.1 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.3 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.4 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.2 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.2 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.3 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.0 0.2 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.1 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.5 GO:0000154 rRNA modification(GO:0000154)
0.0 0.1 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.5 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.1 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.6 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.3 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.3 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.0 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.3 0.8 GO:0030689 Noc complex(GO:0030689)
0.2 1.2 GO:0016938 kinesin I complex(GO:0016938)
0.2 0.7 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.4 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.1 1.0 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.5 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 1.6 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 0.1 GO:0000428 DNA-directed RNA polymerase complex(GO:0000428) RNA polymerase complex(GO:0030880)
0.1 0.3 GO:0034455 t-UTP complex(GO:0034455)
0.1 0.7 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.7 GO:0031415 NatA complex(GO:0031415)
0.1 0.5 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 2.9 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 0.3 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 0.9 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.1 0.4 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 0.5 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.2 GO:0034657 GID complex(GO:0034657)
0.1 0.3 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.1 0.6 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.6 GO:0005638 lamin filament(GO:0005638)
0.1 0.3 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.1 0.7 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.7 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 1.0 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.3 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.3 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 1.4 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.0 0.7 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.6 GO:0034709 methylosome(GO:0034709)
0.0 0.3 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.3 GO:0000796 condensin complex(GO:0000796)
0.0 2.3 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.2 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.8 GO:0071565 nBAF complex(GO:0071565)
0.0 0.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.4 GO:0005686 U2 snRNP(GO:0005686)
0.0 1.0 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.4 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.3 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 1.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.8 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 2.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.1 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.6 GO:0005871 kinesin complex(GO:0005871)
0.0 0.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.9 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 1.6 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.6 GO:0051233 spindle midzone(GO:0051233)
0.0 1.8 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.2 2.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 0.7 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.2 0.7 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.2 0.5 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.1 1.6 GO:0070883 pre-miRNA binding(GO:0070883)
0.1 0.6 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 0.5 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.3 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.7 GO:0050733 RS domain binding(GO:0050733)
0.1 0.8 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.4 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.4 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.3 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 0.3 GO:0031862 prostanoid receptor binding(GO:0031862)
0.1 0.7 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.2 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.1 0.4 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.1 1.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.2 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.1 0.7 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.5 GO:0000403 Y-form DNA binding(GO:0000403)
0.1 0.2 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.1 0.2 GO:0086040 sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086040)
0.1 0.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.2 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.1 0.2 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.5 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.9 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.9 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 1.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.7 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.2 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.0 0.3 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.6 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 0.2 GO:0097001 ceramide binding(GO:0097001)
0.0 0.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.5 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.1 GO:0004823 leucine-tRNA ligase activity(GO:0004823)
0.0 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 1.1 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 1.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.5 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.5 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 1.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.7 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.3 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.5 GO:0000182 rDNA binding(GO:0000182)
0.0 0.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.1 GO:0034039 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity(GO:0034039)
0.0 0.2 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.3 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.2 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.5 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.6 GO:0051400 BH domain binding(GO:0051400)
0.0 3.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.3 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.8 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.9 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.7 GO:0034061 DNA polymerase activity(GO:0034061)
0.0 0.9 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.0 1.6 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.2 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.8 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.1 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.6 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.2 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.1 GO:0004644 phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644)
0.0 0.1 GO:0004057 arginyltransferase activity(GO:0004057)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 2.0 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.1 PID_ATR_PATHWAY ATR signaling pathway
0.0 1.1 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 1.5 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.6 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.7 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 1.1 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.3 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 1.6 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 1.0 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 1.7 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.3 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 0.4 REACTOME_PHOSPHORYLATION_OF_THE_APC_C Genes involved in Phosphorylation of the APC/C
0.1 3.0 REACTOME_KINESINS Genes involved in Kinesins
0.1 1.6 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.1 0.9 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 1.5 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.9 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.9 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.6 REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ Genes involved in Cyclin E associated events during G1/S transition
0.0 1.4 REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.6 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.7 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.7 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.5 REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 1.0 REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.4 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.5 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.7 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.4 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.5 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.6 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.5 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.4 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.3 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.6 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 1.5 REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 1.6 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.3 REACTOME_APOPTOTIC_EXECUTION_PHASE Genes involved in Apoptotic execution phase
0.0 0.5 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 0.0 REACTOME_CDK_MEDIATED_PHOSPHORYLATION_AND_REMOVAL_OF_CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.3 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.2 REACTOME_REGULATION_OF_APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.3 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.8 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation