Motif ID: ZKSCAN1

Z-value: 0.388


Transcription factors associated with ZKSCAN1:

Gene SymbolEntrez IDGene Name
ZKSCAN1 ENSG00000106261.12 ZKSCAN1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZKSCAN1hg19_v2_chr7_+_99613195_99613206-0.442.4e-01Click!


Activity profile for motif ZKSCAN1.

activity profile for motif ZKSCAN1


Sorted Z-values histogram for motif ZKSCAN1

Sorted Z-values for motif ZKSCAN1



Network of associatons between targets according to the STRING database.



First level regulatory network of ZKSCAN1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_4364762 0.557 ENST00000262366.3
 GLIS2
GLIS family zinc finger 2
chr2_+_69201705 0.314 ENST00000377938.2
 GKN1
gastrokine 1
chr16_-_838329 0.284 ENST00000563560.1
ENST00000569601.1
ENST00000565809.1
ENST00000565377.1
ENST00000007264.2
ENST00000567114.1
 RPUSD1





RNA pseudouridylate synthase domain containing 1





chr1_+_65613217 0.241 ENST00000545314.1
 AK4
adenylate kinase 4
chr1_+_65613340 0.241 ENST00000546702.1
 AK4
adenylate kinase 4
chr19_+_39138320 0.231 ENST00000424234.2
ENST00000390009.3
ENST00000589528.1
 ACTN4


actinin, alpha 4


chr16_-_4665023 0.230 ENST00000591897.1
 UBALD1
UBA-like domain containing 1
chr16_-_4664860 0.205 ENST00000587615.1
ENST00000587649.1
ENST00000590965.1
ENST00000591401.1
ENST00000283474.7
 UBALD1




UBA-like domain containing 1




chr17_-_73150599 0.202 ENST00000392566.2
ENST00000581874.1
 HN1

hematological and neurological expressed 1

chr12_+_113416340 0.187 ENST00000552756.1
 OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr2_+_74120094 0.186 ENST00000409731.3
ENST00000345517.3
ENST00000409918.1
ENST00000442912.1
ENST00000409624.1
 ACTG2




actin, gamma 2, smooth muscle, enteric




chr12_+_113416265 0.185 ENST00000449768.2
 OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr22_+_29702572 0.178 ENST00000407647.2
ENST00000416823.1
ENST00000428622.1
 GAS2L1


growth arrest-specific 2 like 1


chr19_+_39138271 0.152 ENST00000252699.2
 ACTN4
actinin, alpha 4
chr19_-_19051993 0.152 ENST00000594794.1
ENST00000355887.6
ENST00000392351.3
ENST00000596482.1
 HOMER3



homer homolog 3 (Drosophila)



chr19_+_39647271 0.139 ENST00000599657.1
 PAK4
p21 protein (Cdc42/Rac)-activated kinase 4
chr9_-_123639445 0.138 ENST00000312189.6
 PHF19
PHD finger protein 19
chr15_+_75494214 0.137 ENST00000394987.4
 C15orf39
chromosome 15 open reading frame 39
chr17_-_73150629 0.135 ENST00000356033.4
ENST00000405458.3
ENST00000409753.3
 HN1


hematological and neurological expressed 1


chr17_+_16945820 0.128 ENST00000577514.1
 MPRIP
myosin phosphatase Rho interacting protein
chr3_-_47023455 0.124 ENST00000446836.1
ENST00000425441.1
 CCDC12

coiled-coil domain containing 12

chr22_-_42739533 0.123 ENST00000515426.1
 TCF20
transcription factor 20 (AR1)
chrX_+_47441712 0.118 ENST00000218388.4
ENST00000377018.2
ENST00000456754.2
ENST00000377017.1
ENST00000441738.1
 TIMP1




TIMP metallopeptidase inhibitor 1




chr9_-_86153218 0.118 ENST00000304195.3
ENST00000376438.1
 FRMD3

FERM domain containing 3

chr15_+_75498739 0.118 ENST00000565074.1
 C15orf39
chromosome 15 open reading frame 39
chr19_-_2739992 0.116 ENST00000545664.1
ENST00000589363.1
ENST00000455372.2
 SLC39A3


solute carrier family 39 (zinc transporter), member 3


chr16_+_67562702 0.114 ENST00000379312.3
ENST00000042381.4
ENST00000540839.3
 FAM65A


family with sequence similarity 65, member A


chr5_-_172756506 0.112 ENST00000265087.4
 STC2
stanniocalcin 2
chr14_+_38033252 0.109 ENST00000554829.1
 RP11-356O9.1
RP11-356O9.1
chr12_+_9066472 0.108 ENST00000538657.1
 PHC1
polyhomeotic homolog 1 (Drosophila)
chr22_-_37640456 0.104 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
 RAC2


ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)


chr22_+_20861858 0.102 ENST00000414658.1
ENST00000432052.1
ENST00000425759.2
ENST00000292733.7
ENST00000542773.1
ENST00000263205.7
ENST00000406969.1
ENST00000382974.2
 MED15







mediator complex subunit 15







chr6_-_30640761 0.099 ENST00000415603.1
 DHX16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr9_+_103189660 0.092 ENST00000374886.3
 MSANTD3
Myb/SANT-like DNA-binding domain containing 3
chr3_-_195310802 0.084 ENST00000421243.1
ENST00000453131.1
 APOD

apolipoprotein D

chr20_+_4152356 0.083 ENST00000379460.2
 SMOX
spermine oxidase
chr2_+_101179152 0.080 ENST00000264254.6
 PDCL3
phosducin-like 3
chr9_-_123639600 0.077 ENST00000373896.3
 PHF19
PHD finger protein 19
chr6_+_36922209 0.077 ENST00000373674.3
 PI16
peptidase inhibitor 16
chr11_-_58343319 0.077 ENST00000395074.2
 LPXN
leupaxin
chr16_+_19729586 0.076 ENST00000564186.1
ENST00000541926.1
ENST00000433597.2
 IQCK


IQ motif containing K


chr17_+_75372165 0.075 ENST00000427674.2
 SEPT9
septin 9
chr10_-_126432619 0.074 ENST00000337318.3
 FAM53B
family with sequence similarity 53, member B
chr16_+_8736232 0.073 ENST00000562973.1
 METTL22
methyltransferase like 22
chr19_-_344786 0.072 ENST00000264819.4
 MIER2
mesoderm induction early response 1, family member 2
chr16_+_67563250 0.069 ENST00000566907.1
 FAM65A
family with sequence similarity 65, member A
chr17_+_17685422 0.068 ENST00000395774.1
 RAI1
retinoic acid induced 1
chr22_+_30805086 0.068 ENST00000439838.1
ENST00000439023.3
 RP4-539M6.19

Uncharacterized protein

chr17_-_40170506 0.068 ENST00000589773.1
ENST00000590348.1
 DNAJC7

DnaJ (Hsp40) homolog, subfamily C, member 7

chr6_-_44281043 0.066 ENST00000244571.4
 AARS2
alanyl-tRNA synthetase 2, mitochondrial
chr3_-_48542197 0.065 ENST00000442747.1
ENST00000444115.1
 SHISA5

shisa family member 5

chr5_-_127873659 0.063 ENST00000262464.4
 FBN2
fibrillin 2
chr6_+_32944119 0.063 ENST00000606059.1
 BRD2
bromodomain containing 2
chr6_-_30640811 0.062 ENST00000376442.3
 DHX16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr17_-_39928501 0.060 ENST00000420370.1
 JUP
junction plakoglobin
chr2_+_113931513 0.059 ENST00000245796.6
ENST00000441564.3
 PSD4

pleckstrin and Sec7 domain containing 4

chr12_+_13197218 0.058 ENST00000197268.8
 KIAA1467
KIAA1467
chr5_-_134735568 0.058 ENST00000510038.1
ENST00000304332.4
 H2AFY

H2A histone family, member Y

chr9_+_103189536 0.056 ENST00000374885.1
 MSANTD3
Myb/SANT-like DNA-binding domain containing 3
chr12_-_123450986 0.055 ENST00000344275.7
ENST00000442833.2
ENST00000280560.8
ENST00000540285.1
ENST00000346530.5
 ABCB9




ATP-binding cassette, sub-family B (MDR/TAP), member 9




chr1_+_27648648 0.052 ENST00000374076.4
 TMEM222
transmembrane protein 222
chr17_+_27071002 0.048 ENST00000262395.5
ENST00000422344.1
ENST00000444415.3
ENST00000262396.6
 TRAF4



TNF receptor-associated factor 4



chr1_+_11333245 0.047 ENST00000376810.5
 UBIAD1
UbiA prenyltransferase domain containing 1
chr7_+_73588575 0.047 ENST00000265753.8
 EIF4H
eukaryotic translation initiation factor 4H
chr12_+_122326630 0.046 ENST00000541212.1
ENST00000340175.5
 PSMD9

proteasome (prosome, macropain) 26S subunit, non-ATPase, 9

chr1_+_16083154 0.046 ENST00000375771.1
 FBLIM1
filamin binding LIM protein 1
chr1_-_53704157 0.046 ENST00000371466.4
ENST00000371470.3
 MAGOH

mago-nashi homolog, proliferation-associated (Drosophila)

chr17_+_26684604 0.044 ENST00000292114.3
ENST00000509083.1
 TMEM199

transmembrane protein 199

chr3_+_51663407 0.044 ENST00000432863.1
ENST00000296477.3
 RAD54L2

RAD54-like 2 (S. cerevisiae)

chr20_-_56265680 0.044 ENST00000414037.1
 PMEPA1
prostate transmembrane protein, androgen induced 1
chr20_-_62199427 0.043 ENST00000427522.2
 HELZ2
helicase with zinc finger 2, transcriptional coactivator
chr11_-_72070206 0.040 ENST00000544382.1
 CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr11_+_70049269 0.039 ENST00000301838.4
 FADD
Fas (TNFRSF6)-associated via death domain
chr15_-_80215984 0.039 ENST00000485386.1
ENST00000479961.1
 ST20
ST20-MTHFS
suppressor of tumorigenicity 20
ST20-MTHFS readthrough
chr19_+_13135790 0.038 ENST00000358552.3
 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr11_+_46366918 0.038 ENST00000528615.1
ENST00000395574.3
 DGKZ

diacylglycerol kinase, zeta

chr19_+_18794470 0.038 ENST00000321949.8
ENST00000338797.6
 CRTC1

CREB regulated transcription coactivator 1

chr5_-_134734901 0.037 ENST00000312469.4
ENST00000423969.2
 H2AFY

H2A histone family, member Y

chr19_+_13135731 0.037 ENST00000587260.1
 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr4_+_39460689 0.037 ENST00000381846.1
 LIAS
lipoic acid synthetase
chr2_-_158345462 0.037 ENST00000439355.1
ENST00000540637.1
 CYTIP

cytohesin 1 interacting protein

chr12_+_122326662 0.036 ENST00000261817.2
ENST00000538613.1
ENST00000542602.1
 PSMD9


proteasome (prosome, macropain) 26S subunit, non-ATPase, 9


chr9_-_139357413 0.035 ENST00000277537.6
 SEC16A
SEC16 homolog A (S. cerevisiae)
chr1_+_27648709 0.034 ENST00000608611.1
ENST00000466759.1
ENST00000464813.1
ENST00000498220.1
 TMEM222



transmembrane protein 222



chr18_+_52495426 0.032 ENST00000262094.5
 RAB27B
RAB27B, member RAS oncogene family
chr5_+_127039075 0.031 ENST00000514853.2
 CTC-228N24.1
CTC-228N24.1
chr4_+_39460620 0.031 ENST00000340169.2
ENST00000261434.3
 LIAS

lipoic acid synthetase

chr19_+_3178736 0.031 ENST00000246115.3
 S1PR4
sphingosine-1-phosphate receptor 4
chr7_+_73588665 0.030 ENST00000353999.6
 EIF4H
eukaryotic translation initiation factor 4H
chr3_+_12329397 0.030 ENST00000397015.2
 PPARG
peroxisome proliferator-activated receptor gamma
chr3_+_12329358 0.029 ENST00000309576.6
 PPARG
peroxisome proliferator-activated receptor gamma
chr5_+_149980622 0.029 ENST00000394243.1
 SYNPO
synaptopodin
chr15_+_40731920 0.029 ENST00000561234.1
 BAHD1
bromo adjacent homology domain containing 1
chr10_-_126432821 0.028 ENST00000280780.6
 FAM53B
family with sequence similarity 53, member B
chr16_+_616995 0.027 ENST00000293874.2
ENST00000409527.2
ENST00000424439.2
ENST00000540585.1
 PIGQ

NHLRC4

phosphatidylinositol glycan anchor biosynthesis, class Q

NHL repeat containing 4

chr11_+_46366799 0.025 ENST00000532868.2
 DGKZ
diacylglycerol kinase, zeta
chr12_+_25055243 0.024 ENST00000599478.1
 AC026310.1
Protein 101060047
chr2_+_27070964 0.024 ENST00000288699.6
 DPYSL5
dihydropyrimidinase-like 5
chr4_+_39460659 0.024 ENST00000513731.1
 LIAS
lipoic acid synthetase
chr17_+_18163848 0.022 ENST00000323019.4
ENST00000578174.1
ENST00000395704.4
ENST00000395703.4
ENST00000578621.1
ENST00000579341.1
 MIEF2





mitochondrial elongation factor 2





chr1_+_226411319 0.021 ENST00000542034.1
ENST00000366810.5
 MIXL1

Mix paired-like homeobox

chr15_-_78369994 0.021 ENST00000300584.3
ENST00000409931.3
 TBC1D2B

TBC1 domain family, member 2B

chr1_-_155224751 0.019 ENST00000350210.2
ENST00000368368.3
 FAM189B

family with sequence similarity 189, member B

chr1_+_156551157 0.018 ENST00000368237.3
 TTC24
tetratricopeptide repeat domain 24
chr15_-_69113218 0.018 ENST00000560303.1
ENST00000465139.2
 ANP32A

acidic (leucine-rich) nuclear phosphoprotein 32 family, member A

chr4_-_176733377 0.017 ENST00000505375.1
 GPM6A
glycoprotein M6A
chr15_-_37390482 0.017 ENST00000559085.1
ENST00000397624.3
 MEIS2

Meis homeobox 2

chr20_-_48770244 0.017 ENST00000371650.5
ENST00000371652.4
ENST00000557021.1
 TMEM189


transmembrane protein 189


chr10_+_112679301 0.016 ENST00000265277.5
ENST00000369452.4
 SHOC2

soc-2 suppressor of clear homolog (C. elegans)

chr9_-_114090713 0.016 ENST00000302681.1
ENST00000374428.1
 OR2K2

olfactory receptor, family 2, subfamily K, member 2

chr2_-_65659762 0.015 ENST00000440972.1
 SPRED2
sprouty-related, EVH1 domain containing 2
chrX_-_130423240 0.015 ENST00000370910.1
ENST00000370901.4
 IGSF1

immunoglobulin superfamily, member 1

chr14_+_103851712 0.015 ENST00000440884.3
ENST00000416682.2
ENST00000429436.2
ENST00000303622.9
 MARK3



MAP/microtubule affinity-regulating kinase 3



chr2_+_231902193 0.014 ENST00000373640.4
 C2orf72
chromosome 2 open reading frame 72
chr6_+_35265586 0.014 ENST00000542066.1
ENST00000316637.5
 DEF6

differentially expressed in FDCP 6 homolog (mouse)

chr16_+_2076869 0.014 ENST00000424542.2
ENST00000432365.2
 SLC9A3R2

solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2

chr12_+_8995832 0.014 ENST00000541459.1
 A2ML1
alpha-2-macroglobulin-like 1
chr15_-_49102781 0.012 ENST00000558591.1
 CEP152
centrosomal protein 152kDa
chrX_+_109245863 0.012 ENST00000372072.3
 TMEM164
transmembrane protein 164
chrX_-_130423200 0.012 ENST00000361420.3
 IGSF1
immunoglobulin superfamily, member 1
chr21_+_18811205 0.012 ENST00000440664.1
 C21orf37
chromosome 21 open reading frame 37
chr9_-_16253112 0.012 ENST00000380683.1
 C9orf92
chromosome 9 open reading frame 92
chr16_+_3550924 0.011 ENST00000576634.1
ENST00000574369.1
ENST00000341633.5
ENST00000417763.2
ENST00000571025.1
 CLUAP1




clusterin associated protein 1




chr12_-_25055177 0.011 ENST00000538118.1
 BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr20_+_44098346 0.011 ENST00000372676.3
 WFDC2
WAP four-disulfide core domain 2
chr10_+_98592674 0.010 ENST00000356016.3
ENST00000371097.4
 LCOR

ligand dependent nuclear receptor corepressor

chr10_+_102222798 0.010 ENST00000343737.5
 WNT8B
wingless-type MMTV integration site family, member 8B
chr1_+_16083098 0.010 ENST00000496928.2
ENST00000508310.1
 FBLIM1

filamin binding LIM protein 1

chr4_-_176733897 0.008 ENST00000393658.2
 GPM6A
glycoprotein M6A
chr2_+_1488435 0.008 ENST00000446278.1
ENST00000469607.1
 TPO

thyroid peroxidase

chr7_+_103969104 0.007 ENST00000424859.1
ENST00000535008.1
ENST00000401970.2
ENST00000543266.1
 LHFPL3



lipoma HMGIC fusion partner-like 3



chr9_+_138413277 0.006 ENST00000263598.2
ENST00000371781.3
 LCN1

lipocalin 1

chr17_+_26800648 0.006 ENST00000545060.1
 SLC13A2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chrX_-_40036520 0.006 ENST00000406200.2
ENST00000378455.4
ENST00000342274.4
 BCOR


BCL6 corepressor


chr1_+_113009163 0.006 ENST00000256640.5
 WNT2B
wingless-type MMTV integration site family, member 2B
chr3_-_179322416 0.005 ENST00000259038.2
 MRPL47
mitochondrial ribosomal protein L47
chr17_+_26800756 0.004 ENST00000537681.1
 SLC13A2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr11_+_33563821 0.004 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
 KIAA1549L


KIAA1549-like


chr3_-_179322436 0.004 ENST00000392659.2
ENST00000476781.1
 MRPL47

mitochondrial ribosomal protein L47

chr15_+_78370140 0.004 ENST00000409568.2
 SH2D7
SH2 domain containing 7
chr13_+_76445187 0.004 ENST00000318245.4
 C13orf45
chromosome 13 open reading frame 45
chr1_-_160549235 0.003 ENST00000368054.3
ENST00000368048.3
ENST00000311224.4
ENST00000368051.3
ENST00000534968.1
 CD84




CD84 molecule




chr14_-_67982146 0.002 ENST00000557779.1
ENST00000557006.1
 TMEM229B

transmembrane protein 229B

chr11_+_133902667 0.001 ENST00000533091.1
ENST00000527712.1
 RP11-713P17.3

RP11-713P17.3

chr19_+_16830815 0.001 ENST00000549814.1
 NWD1
NACHT and WD repeat domain containing 1
chr1_+_16370271 0.001 ENST00000375679.4
 CLCNKB
chloride channel, voltage-sensitive Kb
chr16_+_50313426 0.001 ENST00000569265.1
 ADCY7
adenylate cyclase 7
chr10_-_88281494 0.000 ENST00000298767.5
 WAPAL
wings apart-like homolog (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.6 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
0.0 0.5 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.4 GO:0018377 protein myristoylation(GO:0018377)
0.0 0.1 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:2000097 negative regulation of lipoprotein oxidation(GO:0034443) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.1 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.1 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.0 0.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.0 GO:0072683 T cell extravasation(GO:0072683)
0.0 0.1 GO:0046208 spermine catabolic process(GO:0046208)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0070283 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.0 0.1 GO:0052894 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0005199 structural constituent of cell wall(GO:0005199)
0.0 0.0 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)