Motif ID: ZIC2_GLI1

Z-value: 0.608

Transcription factors associated with ZIC2_GLI1:

Gene SymbolEntrez IDGene Name
GLI1 ENSG00000111087.5 GLI1
ZIC2 ENSG00000043355.6 ZIC2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZIC2hg19_v2_chr13_+_100634004_100634026-0.909.8e-04Click!
GLI1hg19_v2_chr12_+_57857475_578574750.343.7e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of ZIC2_GLI1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_111783919 0.759 ENST00000531198.1
ENST00000533879.1
CRYAB

crystallin, alpha B

chr4_-_186696561 0.703 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
SORBS2





sorbin and SH3 domain containing 2





chr4_-_186696425 0.663 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2


sorbin and SH3 domain containing 2


chr20_+_57430162 0.553 ENST00000450130.1
ENST00000349036.3
ENST00000423897.1
GNAS


GNAS complex locus


chr16_+_56899114 0.527 ENST00000566786.1
ENST00000438926.2
ENST00000563236.1
ENST00000262502.5
SLC12A3



solute carrier family 12 (sodium/chloride transporter), member 3



chr1_-_151798546 0.523 ENST00000356728.6
RORC
RAR-related orphan receptor C
chr19_+_1495362 0.518 ENST00000395479.4
REEP6
receptor accessory protein 6
chr16_+_19183671 0.515 ENST00000562711.2
SYT17
synaptotagmin XVII
chr4_-_186697044 0.469 ENST00000437304.2
SORBS2
sorbin and SH3 domain containing 2
chr4_-_186696515 0.435 ENST00000456596.1
ENST00000414724.1
SORBS2

sorbin and SH3 domain containing 2

chr12_+_57522258 0.429 ENST00000553277.1
ENST00000243077.3
LRP1

low density lipoprotein receptor-related protein 1

chr6_-_26027480 0.426 ENST00000377364.3
HIST1H4B
histone cluster 1, H4b
chr17_-_37557846 0.423 ENST00000394294.3
ENST00000583610.1
ENST00000264658.6
FBXL20


F-box and leucine-rich repeat protein 20


chr12_+_57522692 0.397 ENST00000554174.1
LRP1
low density lipoprotein receptor-related protein 1
chr20_+_43343517 0.373 ENST00000372865.4
WISP2
WNT1 inducible signaling pathway protein 2
chr8_-_17555164 0.364 ENST00000297488.6
MTUS1
microtubule associated tumor suppressor 1
chr4_-_186696636 0.359 ENST00000444771.1
SORBS2
sorbin and SH3 domain containing 2
chr3_+_4535025 0.351 ENST00000302640.8
ENST00000354582.6
ENST00000423119.2
ENST00000357086.4
ENST00000456211.2
ITPR1




inositol 1,4,5-trisphosphate receptor, type 1




chr20_+_43343476 0.345 ENST00000372868.2
WISP2
WNT1 inducible signaling pathway protein 2
chr11_-_111783595 0.345 ENST00000528628.1
CRYAB
crystallin, alpha B
chr21_-_28215332 0.343 ENST00000517777.1
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr14_+_24583836 0.339 ENST00000559115.1
ENST00000558215.1
ENST00000557810.1
ENST00000561375.1
ENST00000446197.3
ENST00000559796.1
ENST00000560713.1
ENST00000560901.1
ENST00000559382.1
DCAF11








DDB1 and CUL4 associated factor 11








chr2_+_46769798 0.337 ENST00000238738.4
RHOQ
ras homolog family member Q
chr14_+_24584372 0.325 ENST00000559396.1
ENST00000558638.1
ENST00000561041.1
ENST00000559288.1
ENST00000558408.1
DCAF11




DDB1 and CUL4 associated factor 11




chr9_-_123476612 0.323 ENST00000426959.1
MEGF9
multiple EGF-like-domains 9
chr20_+_43343886 0.316 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chr19_+_3708376 0.314 ENST00000539908.2
TJP3
tight junction protein 3
chr10_+_99344071 0.310 ENST00000370647.4
ENST00000370646.4
HOGA1

4-hydroxy-2-oxoglutarate aldolase 1

chr14_+_24584508 0.307 ENST00000559354.1
ENST00000560459.1
ENST00000559593.1
ENST00000396941.4
ENST00000396936.1
DCAF11




DDB1 and CUL4 associated factor 11




chr17_-_34122596 0.302 ENST00000250144.8
MMP28
matrix metallopeptidase 28
chr3_+_4535155 0.300 ENST00000544951.1
ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr6_+_33172407 0.300 ENST00000374662.3
HSD17B8
hydroxysteroid (17-beta) dehydrogenase 8
chr5_+_52776449 0.297 ENST00000396947.3
FST
follistatin
chr17_-_37558776 0.269 ENST00000577399.1
FBXL20
F-box and leucine-rich repeat protein 20
chr5_+_52776228 0.256 ENST00000256759.3
FST
follistatin
chr5_-_138739739 0.256 ENST00000514983.1
ENST00000507779.2
ENST00000451821.2
ENST00000450845.2
ENST00000509959.1
ENST00000302091.5
SPATA24





spermatogenesis associated 24





chr3_-_52486841 0.248 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr8_-_117886955 0.243 ENST00000297338.2
RAD21
RAD21 homolog (S. pombe)
chr11_+_117049910 0.238 ENST00000431081.2
ENST00000524842.1
SIDT2

SID1 transmembrane family, member 2

chr10_-_90712520 0.237 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr3_+_113616317 0.234 ENST00000440446.2
ENST00000488680.1
GRAMD1C

GRAM domain containing 1C

chr9_-_33264676 0.231 ENST00000472232.3
ENST00000379704.2
BAG1

BCL2-associated athanogene

chr9_-_33264557 0.228 ENST00000473781.1
ENST00000488499.1
BAG1

BCL2-associated athanogene

chr14_+_24584056 0.227 ENST00000561001.1
DCAF11
DDB1 and CUL4 associated factor 11
chr17_-_7137582 0.226 ENST00000575756.1
ENST00000575458.1
DVL2

dishevelled segment polarity protein 2

chr17_-_7137857 0.223 ENST00000005340.5
DVL2
dishevelled segment polarity protein 2
chr3_+_10068095 0.219 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
FANCD2



Fanconi anemia, complementation group D2



chr19_-_44285401 0.219 ENST00000262888.3
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr1_-_12677714 0.210 ENST00000376223.2
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr11_-_111782696 0.209 ENST00000227251.3
ENST00000526180.1
CRYAB

crystallin, alpha B

chr12_+_57522439 0.209 ENST00000338962.4
LRP1
low density lipoprotein receptor-related protein 1
chr10_+_180405 0.196 ENST00000439456.1
ENST00000397962.3
ENST00000309776.4
ENST00000381602.4
ZMYND11



zinc finger, MYND-type containing 11



chr6_+_43968306 0.196 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223


chromosome 6 open reading frame 223


chrX_+_70364667 0.193 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
NLGN3



neuroligin 3



chr21_-_28217721 0.191 ENST00000284984.3
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr14_+_64971292 0.190 ENST00000358738.3
ENST00000394712.2
ZBTB1

zinc finger and BTB domain containing 1

chr11_-_6640585 0.181 ENST00000533371.1
ENST00000528657.1
ENST00000436873.2
ENST00000299427.6
TPP1



tripeptidyl peptidase I



chr13_+_20532848 0.181 ENST00000382874.2
ZMYM2
zinc finger, MYM-type 2
chr14_-_64971288 0.180 ENST00000394715.1
ZBTB25
zinc finger and BTB domain containing 25
chr20_+_32319463 0.176 ENST00000342427.2
ENST00000375200.1
ZNF341

zinc finger protein 341

chr9_-_123476719 0.175 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr22_-_19165917 0.174 ENST00000451283.1
SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr22_-_19166343 0.173 ENST00000215882.5
SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr1_+_44679113 0.173 ENST00000361745.6
ENST00000446292.1
ENST00000440641.1
ENST00000436069.1
ENST00000437511.1
DMAP1




DNA methyltransferase 1 associated protein 1




chr15_-_43882140 0.172 ENST00000429176.1
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr3_-_129513259 0.171 ENST00000329333.5
TMCC1
transmembrane and coiled-coil domain family 1
chr1_+_44679159 0.170 ENST00000315913.5
ENST00000372289.2
DMAP1

DNA methyltransferase 1 associated protein 1

chr20_+_57427765 0.167 ENST00000371100.4
GNAS
GNAS complex locus
chr5_-_137090028 0.163 ENST00000314940.4
HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr8_-_117886732 0.163 ENST00000517485.1
RAD21
RAD21 homolog (S. pombe)
chr13_+_20532807 0.161 ENST00000382869.3
ENST00000382881.3
ZMYM2

zinc finger, MYM-type 2

chr13_+_20532900 0.157 ENST00000382871.2
ZMYM2
zinc finger, MYM-type 2
chr9_+_33265011 0.155 ENST00000419016.2
CHMP5
charged multivesicular body protein 5
chr3_-_135915401 0.153 ENST00000491050.1
MSL2
male-specific lethal 2 homolog (Drosophila)
chr1_+_44679370 0.149 ENST00000372290.4
DMAP1
DNA methyltransferase 1 associated protein 1
chr6_+_160183492 0.147 ENST00000541436.1
ACAT2
acetyl-CoA acetyltransferase 2
chr9_+_33264861 0.146 ENST00000223500.8
CHMP5
charged multivesicular body protein 5
chr8_-_94752946 0.145 ENST00000519109.1
RBM12B
RNA binding motif protein 12B
chr10_+_180643 0.145 ENST00000509513.2
ENST00000397959.3
ZMYND11

zinc finger, MYND-type containing 11

chr12_-_120966943 0.141 ENST00000552443.1
ENST00000547736.1
ENST00000445328.2
ENST00000547943.1
ENST00000288532.6
COQ5




coenzyme Q5 homolog, methyltransferase (S. cerevisiae)




chr8_-_117886612 0.139 ENST00000520992.1
RAD21
RAD21 homolog (S. pombe)
chr11_-_111784005 0.139 ENST00000527899.1
CRYAB
crystallin, alpha B
chr11_-_34937858 0.136 ENST00000278359.5
APIP
APAF1 interacting protein
chr3_-_10028366 0.134 ENST00000429759.1
EMC3
ER membrane protein complex subunit 3
chr11_-_34938039 0.133 ENST00000395787.3
APIP
APAF1 interacting protein
chr1_+_209941942 0.132 ENST00000487271.1
ENST00000477431.1
TRAF3IP3

TRAF3 interacting protein 3

chr11_-_46142948 0.131 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr10_-_81203972 0.130 ENST00000372333.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr19_-_40919271 0.126 ENST00000291825.7
ENST00000324001.7
PRX

periaxin

chr8_+_75736761 0.123 ENST00000260113.2
PI15
peptidase inhibitor 15
chrX_+_12809463 0.121 ENST00000380663.3
ENST00000380668.5
ENST00000398491.2
ENST00000489404.1
PRPS2



phosphoribosyl pyrophosphate synthetase 2



chr11_-_61124266 0.121 ENST00000539890.1
CYB561A3
cytochrome b561 family, member A3
chr8_-_117886563 0.117 ENST00000519837.1
ENST00000522699.1
RAD21

RAD21 homolog (S. pombe)

chr7_+_69064300 0.116 ENST00000342771.4
AUTS2
autism susceptibility candidate 2
chr11_+_111782934 0.116 ENST00000304298.3
HSPB2
Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr20_+_62327996 0.115 ENST00000369996.1
TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr5_+_162864575 0.111 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
CCNG1






cyclin G1






chr3_-_88108192 0.111 ENST00000309534.6
CGGBP1
CGG triplet repeat binding protein 1
chr2_+_178977143 0.109 ENST00000286070.5
RBM45
RNA binding motif protein 45
chr22_+_38035459 0.104 ENST00000357436.4
SH3BP1
SH3-domain binding protein 1
chr3_+_110790715 0.104 ENST00000319792.3
PVRL3
poliovirus receptor-related 3
chr3_+_110790867 0.103 ENST00000486596.1
ENST00000493615.1
PVRL3

poliovirus receptor-related 3

chr4_-_187517928 0.101 ENST00000512772.1
FAT1
FAT atypical cadherin 1
chr22_+_38035623 0.100 ENST00000336738.5
ENST00000442465.2
SH3BP1

SH3-domain binding protein 1

chr11_+_34073195 0.099 ENST00000341394.4
CAPRIN1
cell cycle associated protein 1
chrX_-_37706661 0.095 ENST00000432389.2
ENST00000378581.3
DYNLT3

dynein, light chain, Tctex-type 3

chr3_+_110790590 0.095 ENST00000485303.1
PVRL3
poliovirus receptor-related 3
chr1_-_147142557 0.095 ENST00000369238.6
ACP6
acid phosphatase 6, lysophosphatidic
chr6_-_29600832 0.094 ENST00000377016.4
ENST00000376977.3
ENST00000377034.4
GABBR1


gamma-aminobutyric acid (GABA) B receptor, 1


chrX_-_140271249 0.092 ENST00000370526.2
LDOC1
leucine zipper, down-regulated in cancer 1
chr5_-_36241900 0.088 ENST00000381937.4
ENST00000514504.1
NADK2

NAD kinase 2, mitochondrial

chr18_+_21529811 0.086 ENST00000588004.1
LAMA3
laminin, alpha 3
chrX_+_51636629 0.086 ENST00000375722.1
ENST00000326587.7
ENST00000375695.2
MAGED1


melanoma antigen family D, 1


chr22_-_28197486 0.086 ENST00000302326.4
MN1
meningioma (disrupted in balanced translocation) 1
chr15_-_83224682 0.084 ENST00000562833.1
RP11-152F13.10
RP11-152F13.10
chr1_+_6673745 0.082 ENST00000377648.4
PHF13
PHD finger protein 13
chr19_+_1383890 0.079 ENST00000539480.1
ENST00000313408.7
ENST00000414651.2
NDUFS7


NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)


chr16_+_28875268 0.077 ENST00000395532.4
SH2B1
SH2B adaptor protein 1
chr12_-_122018114 0.076 ENST00000539394.1
KDM2B
lysine (K)-specific demethylase 2B
chr1_-_161014731 0.076 ENST00000368020.1
USF1
upstream transcription factor 1
chr12_+_117176090 0.075 ENST00000257575.4
ENST00000407967.3
ENST00000392549.2
RNFT2


ring finger protein, transmembrane 2


chr6_+_125540951 0.075 ENST00000524679.1
TPD52L1
tumor protein D52-like 1
chr2_-_25016251 0.075 ENST00000328379.5
PTRHD1
peptidyl-tRNA hydrolase domain containing 1
chr17_-_3819751 0.072 ENST00000225538.3
P2RX1
purinergic receptor P2X, ligand-gated ion channel, 1
chr9_+_8858102 0.071 ENST00000447950.1
ENST00000430766.1
RP11-75C9.1

RP11-75C9.1

chr5_-_36242119 0.070 ENST00000511088.1
ENST00000282512.3
ENST00000506945.1
NADK2


NAD kinase 2, mitochondrial


chrX_+_54835493 0.070 ENST00000396224.1
MAGED2
melanoma antigen family D, 2
chr7_+_116312411 0.070 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
MET


met proto-oncogene


chr9_-_130639997 0.069 ENST00000373176.1
AK1
adenylate kinase 1
chr11_-_46142615 0.069 ENST00000529734.1
ENST00000323180.6
PHF21A

PHD finger protein 21A

chr9_+_22446814 0.069 ENST00000325870.2
DMRTA1
DMRT-like family A1
chr17_+_4736627 0.068 ENST00000355280.6
ENST00000347992.7
MINK1

misshapen-like kinase 1

chr15_+_60296421 0.068 ENST00000396057.4
FOXB1
forkhead box B1
chr11_+_34073269 0.068 ENST00000389645.3
CAPRIN1
cell cycle associated protein 1
chrX_-_107334790 0.067 ENST00000217958.3
PSMD10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr11_+_64001962 0.066 ENST00000309422.2
VEGFB
vascular endothelial growth factor B
chrM_+_7586 0.066 ENST00000361739.1
MT-CO2
mitochondrially encoded cytochrome c oxidase II
chr17_-_26989136 0.064 ENST00000247020.4
SDF2
stromal cell-derived factor 2
chr12_+_117176113 0.061 ENST00000319176.7
RNFT2
ring finger protein, transmembrane 2
chr2_+_106361333 0.060 ENST00000233154.4
ENST00000451463.2
NCK2

NCK adaptor protein 2

chr10_-_97050777 0.058 ENST00000329399.6
PDLIM1
PDZ and LIM domain 1
chr7_-_100034060 0.058 ENST00000292330.2
PPP1R35
protein phosphatase 1, regulatory subunit 35
chr17_+_43239191 0.058 ENST00000589230.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr2_+_68694678 0.057 ENST00000303795.4
APLF
aprataxin and PNKP like factor
chr3_-_8686479 0.057 ENST00000544814.1
ENST00000427408.1
SSUH2

ssu-2 homolog (C. elegans)

chr1_-_21606013 0.056 ENST00000357071.4
ECE1
endothelin converting enzyme 1
chr19_+_45312347 0.056 ENST00000270233.6
ENST00000591520.1
BCAM

basal cell adhesion molecule (Lutheran blood group)

chr11_+_45944190 0.055 ENST00000401752.1
ENST00000389968.3
ENST00000325468.5
ENST00000536139.1
GYLTL1B



glycosyltransferase-like 1B



chr19_+_50354462 0.055 ENST00000601675.1
PTOV1
prostate tumor overexpressed 1
chr3_+_49449636 0.054 ENST00000273590.3
TCTA
T-cell leukemia translocation altered
chr11_+_33278811 0.054 ENST00000303296.4
ENST00000379016.3
HIPK3

homeodomain interacting protein kinase 3

chrX_-_107334750 0.053 ENST00000340200.5
ENST00000372296.1
ENST00000372295.1
ENST00000361815.5
PSMD10



proteasome (prosome, macropain) 26S subunit, non-ATPase, 10



chr19_+_45312310 0.052 ENST00000589651.1
BCAM
basal cell adhesion molecule (Lutheran blood group)
chr11_-_111782484 0.052 ENST00000533971.1
CRYAB
crystallin, alpha B
chr1_+_203595903 0.052 ENST00000367218.3
ENST00000367219.3
ENST00000391954.2
ATP2B4


ATPase, Ca++ transporting, plasma membrane 4


chr17_+_73997419 0.051 ENST00000425876.2
CDK3
cyclin-dependent kinase 3
chr1_+_154966058 0.051 ENST00000392487.1
LENEP
lens epithelial protein
chr17_+_4843594 0.050 ENST00000570328.1
RNF167
ring finger protein 167
chr12_-_25403737 0.049 ENST00000256078.4
ENST00000556131.1
ENST00000311936.3
ENST00000557334.1
KRAS



Kirsten rat sarcoma viral oncogene homolog



chr6_+_292253 0.049 ENST00000603453.1
ENST00000605315.1
ENST00000603881.1
DUSP22


dual specificity phosphatase 22


chr11_-_65321198 0.049 ENST00000530426.1
LTBP3
latent transforming growth factor beta binding protein 3
chr11_+_34938119 0.046 ENST00000227868.4
ENST00000430469.2
ENST00000533262.1
PDHX


pyruvate dehydrogenase complex, component X


chr5_+_175792459 0.043 ENST00000310389.5
ARL10
ADP-ribosylation factor-like 10
chr8_-_71581377 0.043 ENST00000276590.4
ENST00000522447.1
LACTB2

lactamase, beta 2

chr17_-_40835076 0.043 ENST00000591765.1
CCR10
chemokine (C-C motif) receptor 10
chr10_-_98346801 0.043 ENST00000371142.4
TM9SF3
transmembrane 9 superfamily member 3
chr11_-_30607819 0.043 ENST00000448418.2
MPPED2
metallophosphoesterase domain containing 2
chr1_-_202776392 0.042 ENST00000235790.4
KDM5B
lysine (K)-specific demethylase 5B
chr17_-_74533734 0.042 ENST00000589342.1
CYGB
cytoglobin
chr11_+_933555 0.042 ENST00000534485.1
AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr10_+_24755416 0.042 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217


KIAA1217


chr3_-_49449521 0.041 ENST00000431929.1
ENST00000418115.1
RHOA

ras homolog family member A

chr2_+_159825143 0.041 ENST00000454300.1
ENST00000263635.6
TANC1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr1_-_38512450 0.038 ENST00000373012.2
POU3F1
POU class 3 homeobox 1
chrX_+_48687283 0.037 ENST00000338270.1
ERAS
ES cell expressed Ras
chr2_-_46769694 0.036 ENST00000522587.1
ATP6V1E2
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
chr9_-_116159635 0.036 ENST00000452726.1
ALAD
aminolevulinate dehydratase
chr9_-_136242909 0.035 ENST00000371991.3
ENST00000545297.1
SURF4

surfeit 4

chr22_-_30783356 0.035 ENST00000382363.3
RNF215
ring finger protein 215
chr17_+_40834580 0.034 ENST00000264638.4
CNTNAP1
contactin associated protein 1
chr19_+_4969116 0.034 ENST00000588337.1
ENST00000159111.4
ENST00000381759.4
KDM4B


lysine (K)-specific demethylase 4B


chr4_+_37978891 0.032 ENST00000446803.2
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr14_+_77228532 0.032 ENST00000167106.4
ENST00000554237.1
VASH1

vasohibin 1

chr1_+_32674675 0.030 ENST00000409358.1
DCDC2B
doublecortin domain containing 2B
chr1_-_45308616 0.029 ENST00000447098.2
ENST00000372192.3
PTCH2

patched 2

chr1_+_24120143 0.029 ENST00000374501.1
LYPLA2
lysophospholipase II
chr9_-_124989804 0.029 ENST00000373755.2
ENST00000373754.2
LHX6

LIM homeobox 6

chr19_-_39330818 0.029 ENST00000594769.1
ENST00000602021.1
AC104534.3

Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

chr19_-_13617037 0.027 ENST00000360228.5
CACNA1A
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr11_+_111783450 0.027 ENST00000537382.1
HSPB2
Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr15_-_65282274 0.027 ENST00000204566.2
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr13_+_44947941 0.026 ENST00000379179.3
SERP2
stress-associated endoplasmic reticulum protein family member 2
chr4_-_1657135 0.025 ENST00000489029.1
FAM53A
family with sequence similarity 53, member A
chr17_+_43299156 0.025 ENST00000331495.3
FMNL1
formin-like 1
chr14_-_70655684 0.025 ENST00000356921.2
ENST00000381269.2
ENST00000357887.3
SLC8A3


solute carrier family 8 (sodium/calcium exchanger), member 3


chr22_-_30783075 0.025 ENST00000215798.6
RNF215
ring finger protein 215
chr17_-_28618867 0.025 ENST00000394819.3
ENST00000577623.1
BLMH

bleomycin hydrolase

chr15_-_65282232 0.025 ENST00000416889.2
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr7_-_150777874 0.024 ENST00000540185.1
FASTK
Fas-activated serine/threonine kinase
chr6_+_43739697 0.024 ENST00000230480.6
VEGFA
vascular endothelial growth factor A

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.4 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 0.7 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.7 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.3 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1 0.2 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.1 0.3 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 1.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.5 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 2.6 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.3 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.1 0.7 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.2 GO:0060024 rhythmic synaptic transmission(GO:0060024) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.2 GO:2000174 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.5 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.3 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:0046541 saliva secretion(GO:0046541)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0007272 ensheathment of neurons(GO:0007272) axon ensheathment(GO:0008366)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.5 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.5 GO:0060850 regulation of transcription involved in cell fate commitment(GO:0060850)
0.0 0.2 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.3 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.1 GO:0033242 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.0 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.0 GO:0010360 negative regulation of anion channel activity(GO:0010360) Golgi to plasma membrane CFTR protein transport(GO:0043000)
0.0 0.1 GO:0002351 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
0.0 0.1 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 0.0 GO:2000861 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.0 GO:0002034 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) beta selection(GO:0043366)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:0060137 maternal process involved in parturition(GO:0060137)
0.0 0.1 GO:0060179 male mating behavior(GO:0060179)
0.0 0.1 GO:0000429 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436)
0.0 0.5 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.1 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 1.5 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.7 GO:0000798 nuclear cohesin complex(GO:0000798)
0.1 0.6 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 1.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.2 0.7 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.3 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.1 0.3 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.3 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1 2.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.7 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.3 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.5 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.2 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0005055 laminin receptor activity(GO:0005055)
0.0 0.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.5 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 1.0 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.2 GO:0031014 troponin T binding(GO:0031014)
0.0 0.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.0 GO:1904854 proteasome core complex binding(GO:1904854)
0.0 0.0 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.0 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 0.7 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.0 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.4 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.7 REACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION Genes involved in Glucagon signaling in metabolic regulation