Motif ID: ZBTB49

Z-value: 0.347


Transcription factors associated with ZBTB49:

Gene SymbolEntrez IDGene Name
ZBTB49 ENSG00000168826.11 ZBTB49

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZBTB49hg19_v2_chr4_+_4291924_42920110.854.0e-03Click!


Activity profile for motif ZBTB49.

activity profile for motif ZBTB49


Sorted Z-values histogram for motif ZBTB49

Sorted Z-values for motif ZBTB49



Network of associatons between targets according to the STRING database.



First level regulatory network of ZBTB49

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_79115503 0.833 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
 IFI44


interferon-induced protein 44


chr9_-_123676827 0.299 ENST00000546084.1
 TRAF1
TNF receptor-associated factor 1
chr3_-_172428842 0.231 ENST00000424772.1
 NCEH1
neutral cholesterol ester hydrolase 1
chrX_+_16185604 0.226 ENST00000400004.2
 MAGEB17
melanoma antigen family B, 17
chr11_-_2950642 0.226 ENST00000314222.4
 PHLDA2
pleckstrin homology-like domain, family A, member 2
chr3_-_172428959 0.216 ENST00000475381.1
ENST00000538775.1
ENST00000273512.3
ENST00000543711.1
 NCEH1



neutral cholesterol ester hydrolase 1



chr14_-_23446900 0.193 ENST00000556731.1
 AJUBA
ajuba LIM protein
chr19_-_54567035 0.119 ENST00000366170.2
ENST00000425006.2
 VSTM1

V-set and transmembrane domain containing 1

chr18_+_32558380 0.115 ENST00000588349.2
 MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr12_+_104324112 0.114 ENST00000299767.5
 HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr11_+_43702322 0.111 ENST00000395700.4
 HSD17B12
hydroxysteroid (17-beta) dehydrogenase 12
chr16_+_69166418 0.110 ENST00000314423.7
ENST00000562237.1
ENST00000567460.1
ENST00000566227.1
ENST00000352319.4
ENST00000563094.1
 CIRH1A





cirrhosis, autosomal recessive 1A (cirhin)





chr8_+_99129513 0.108 ENST00000522319.1
ENST00000401707.2
 POP1

processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)

chr16_+_30406721 0.108 ENST00000320159.2
 ZNF48
zinc finger protein 48
chr3_+_39424828 0.107 ENST00000273158.4
ENST00000431510.1
 SLC25A38

solute carrier family 25, member 38

chr19_+_50145328 0.101 ENST00000360565.3
 SCAF1
SR-related CTD-associated factor 1
chr18_+_32558208 0.099 ENST00000436190.2
 MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr13_-_100624012 0.097 ENST00000267294.4
 ZIC5
Zic family member 5
chr5_-_180229833 0.093 ENST00000307826.4
 MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chrX_+_52780318 0.088 ENST00000375515.3
ENST00000276049.6
 SSX2B

synovial sarcoma, X breakpoint 2B

chr3_+_196594727 0.088 ENST00000445299.2
ENST00000323460.5
ENST00000419026.1
 SENP5


SUMO1/sentrin specific peptidase 5


chr7_-_44613494 0.086 ENST00000431640.1
ENST00000258772.5
 DDX56

DEAD (Asp-Glu-Ala-Asp) box helicase 56

chrX_+_64887512 0.084 ENST00000360270.5
 MSN
moesin
chr16_+_2533020 0.083 ENST00000562105.1
 TBC1D24
TBC1 domain family, member 24
chr22_-_37915247 0.076 ENST00000251973.5
 CARD10
caspase recruitment domain family, member 10
chr16_+_30406423 0.076 ENST00000524644.1
 ZNF48
zinc finger protein 48
chr8_-_82024290 0.075 ENST00000220597.4
 PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr5_+_140474181 0.075 ENST00000194155.4
 PCDHB2
protocadherin beta 2
chr3_+_52232102 0.073 ENST00000469224.1
ENST00000394965.2
ENST00000310271.2
ENST00000484952.1
 ALAS1



aminolevulinate, delta-, synthase 1



chr3_-_196242233 0.072 ENST00000397537.2
 SMCO1
single-pass membrane protein with coiled-coil domains 1
chr2_-_85555355 0.069 ENST00000282120.2
ENST00000398263.2
 TGOLN2

trans-golgi network protein 2

chr16_-_18937726 0.069 ENST00000389467.3
ENST00000446231.2
 SMG1

SMG1 phosphatidylinositol 3-kinase-related kinase

chr19_-_4182530 0.068 ENST00000601571.1
ENST00000601488.1
ENST00000305232.6
ENST00000381935.3
ENST00000337491.2
 SIRT6




sirtuin 6




chrX_+_151903253 0.067 ENST00000452779.2
ENST00000370291.2
 CSAG1

chondrosarcoma associated gene 1

chr20_+_33134619 0.066 ENST00000374837.3
 MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr6_-_159240415 0.066 ENST00000367075.3
 EZR
ezrin
chr8_-_59572093 0.065 ENST00000427130.2
 NSMAF
neutral sphingomyelinase (N-SMase) activation associated factor
chr16_-_18937480 0.064 ENST00000532700.2
 SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr6_+_53659746 0.063 ENST00000370888.1
 LRRC1
leucine rich repeat containing 1
chr19_-_59070239 0.059 ENST00000595957.1
ENST00000253023.3
 UBE2M

ubiquitin-conjugating enzyme E2M

chr16_+_28722809 0.055 ENST00000566866.1
 EIF3C
eukaryotic translation initiation factor 3, subunit C
chr8_-_99129338 0.053 ENST00000520507.1
 HRSP12
heat-responsive protein 12
chr10_+_94352956 0.052 ENST00000260731.3
 KIF11
kinesin family member 11
chr16_-_28415162 0.050 ENST00000398944.3
ENST00000398943.3
ENST00000380876.4
 EIF3CL


eukaryotic translation initiation factor 3, subunit C-like


chr20_+_5731083 0.049 ENST00000445603.1
ENST00000442185.1
 C20orf196

chromosome 20 open reading frame 196

chr16_+_28722684 0.048 ENST00000331666.6
ENST00000395587.1
ENST00000569690.1
ENST00000564243.1
 EIF3C



eukaryotic translation initiation factor 3, subunit C



chr22_-_20255212 0.047 ENST00000416372.1
 RTN4R
reticulon 4 receptor
chr14_+_79745746 0.047 ENST00000281127.7
 NRXN3
neurexin 3
chr14_-_35591679 0.046 ENST00000557278.1
 PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr14_+_79746249 0.045 ENST00000428277.2
 NRXN3
neurexin 3
chr15_+_90728145 0.045 ENST00000561085.1
ENST00000379122.3
ENST00000332496.6
 SEMA4B


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B


chr20_+_1115821 0.044 ENST00000435720.1
 PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr14_+_77924204 0.044 ENST00000555133.1
 AHSA1
AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
chr2_+_30670209 0.043 ENST00000497423.1
ENST00000476535.1
 LCLAT1

lysocardiolipin acyltransferase 1

chr5_+_98264867 0.042 ENST00000513175.1
 CTD-2007H13.3
CTD-2007H13.3
chr2_-_85555086 0.041 ENST00000444342.2
ENST00000409232.3
ENST00000409015.1
 TGOLN2


trans-golgi network protein 2


chr1_+_182808474 0.041 ENST00000367549.3
 DHX9
DEAH (Asp-Glu-Ala-His) box helicase 9
chr8_-_99129384 0.041 ENST00000521560.1
ENST00000254878.3
 HRSP12

heat-responsive protein 12

chr10_+_81466084 0.041 ENST00000342531.2
 NUTM2B
NUT family member 2B
chr12_+_53835383 0.040 ENST00000429243.2
 PRR13
proline rich 13
chr12_+_53835539 0.038 ENST00000547368.1
ENST00000379786.4
ENST00000551945.1
 PRR13


proline rich 13


chr8_+_24151553 0.038 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
 ADAM28


ADAM metallopeptidase domain 28


chr2_+_30670127 0.037 ENST00000540623.1
ENST00000476038.1
 LCLAT1

lysocardiolipin acyltransferase 1

chr12_+_53835508 0.037 ENST00000541275.1
ENST00000551003.1
ENST00000549068.1
ENST00000549740.1
ENST00000546581.1
ENST00000549581.1
 PCBP2
PRR13




poly(rC) binding protein 2
proline rich 13




chr2_+_27237615 0.036 ENST00000458529.1
ENST00000402218.1
 MAPRE3

microtubule-associated protein, RP/EB family, member 3

chr19_+_18669809 0.035 ENST00000602094.1
 KXD1
KxDL motif containing 1
chr14_+_79745682 0.034 ENST00000557594.1
 NRXN3
neurexin 3
chr21_-_26979786 0.033 ENST00000419219.1
ENST00000352957.4
ENST00000307301.7
 MRPL39


mitochondrial ribosomal protein L39


chr2_+_30670077 0.033 ENST00000466477.1
ENST00000465200.1
ENST00000379509.3
ENST00000319406.4
ENST00000488144.1
ENST00000465538.1
ENST00000309052.4
ENST00000359433.1
 LCLAT1







lysocardiolipin acyltransferase 1







chr18_+_43753500 0.032 ENST00000587591.1
ENST00000588730.1
 C18orf25

chromosome 18 open reading frame 25

chr15_-_25684110 0.032 ENST00000232165.3
 UBE3A
ubiquitin protein ligase E3A
chr10_+_90750493 0.032 ENST00000357339.2
ENST00000355279.2
 FAS

Fas cell surface death receptor

chr6_+_170863353 0.032 ENST00000421512.1
 TBP
TATA box binding protein
chr1_-_110933611 0.031 ENST00000472422.2
ENST00000437429.2
 SLC16A4

solute carrier family 16, member 4

chr12_+_53835425 0.030 ENST00000549924.1
 PRR13
proline rich 13
chr2_+_234160340 0.029 ENST00000417017.1
ENST00000392020.4
ENST00000392018.1
 ATG16L1


autophagy related 16-like 1 (S. cerevisiae)


chr15_+_75639773 0.027 ENST00000567657.1
 NEIL1
nei endonuclease VIII-like 1 (E. coli)
chr2_+_27498289 0.027 ENST00000296097.3
ENST00000420191.1
 DNAJC5G

DnaJ (Hsp40) homolog, subfamily C, member 5 gamma

chr9_+_26956371 0.026 ENST00000380062.5
ENST00000518614.1
 IFT74

intraflagellar transport 74 homolog (Chlamydomonas)

chr2_+_234160217 0.025 ENST00000392017.4
ENST00000347464.5
ENST00000444735.1
ENST00000373525.5
ENST00000419681.1
 ATG16L1




autophagy related 16-like 1 (S. cerevisiae)




chr7_+_148936732 0.025 ENST00000335870.2
 ZNF212
zinc finger protein 212
chr1_-_110933663 0.024 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
 SLC16A4


solute carrier family 16, member 4


chr1_-_36863481 0.023 ENST00000315732.2
 LSM10
LSM10, U7 small nuclear RNA associated
chr7_+_99006232 0.023 ENST00000403633.2
 BUD31
BUD31 homolog (S. cerevisiae)
chr9_+_26956474 0.022 ENST00000429045.2
 IFT74
intraflagellar transport 74 homolog (Chlamydomonas)
chr22_-_20256054 0.021 ENST00000043402.7
 RTN4R
reticulon 4 receptor
chr10_-_12084770 0.018 ENST00000357604.5
 UPF2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr6_-_49604545 0.017 ENST00000371175.4
ENST00000229810.7
 RHAG

Rh-associated glycoprotein

chrX_-_151903184 0.017 ENST00000357916.4
ENST00000393869.3
 MAGEA12

melanoma antigen family A, 12

chr15_+_75639372 0.017 ENST00000566313.1
ENST00000568059.1
ENST00000568881.1
 NEIL1


nei endonuclease VIII-like 1 (E. coli)


chr3_+_196669494 0.016 ENST00000602845.1
 NCBP2-AS2
NCBP2 antisense RNA 2 (head to head)
chr8_-_42396632 0.015 ENST00000520179.1
 SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr8_+_24151620 0.015 ENST00000437154.2
 ADAM28
ADAM metallopeptidase domain 28
chr1_+_240255166 0.015 ENST00000319653.9
 FMN2
formin 2
chr22_+_21996549 0.014 ENST00000248958.4
 SDF2L1
stromal cell-derived factor 2-like 1
chr12_-_120241187 0.014 ENST00000392520.2
 CIT
citron (rho-interacting, serine/threonine kinase 21)
chrX_-_151903101 0.012 ENST00000393900.3
 MAGEA12
melanoma antigen family A, 12
chr14_+_35591509 0.012 ENST00000604073.1
 KIAA0391
KIAA0391
chr14_-_35591156 0.011 ENST00000554361.1
 PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr2_-_48982708 0.008 ENST00000428232.1
ENST00000405626.1
ENST00000294954.7
 LHCGR


luteinizing hormone/choriogonadotropin receptor


chr8_+_95653302 0.008 ENST00000423620.2
ENST00000433389.2
 ESRP1

epithelial splicing regulatory protein 1

chr9_-_97401782 0.008 ENST00000375326.4
 FBP1
fructose-1,6-bisphosphatase 1
chr11_-_3253592 0.007 ENST00000389832.5
ENST00000436689.2
 MRGPRE

MAS-related GPR, member E

chr6_-_109777128 0.007 ENST00000358807.3
ENST00000358577.3
 MICAL1

microtubule associated monooxygenase, calponin and LIM domain containing 1

chr4_-_2243839 0.005 ENST00000511885.2
ENST00000506763.1
ENST00000514395.1
ENST00000502440.1
ENST00000243706.4
ENST00000443786.2
 POLN
HAUS3




polymerase (DNA directed) nu
HAUS augmin-like complex, subunit 3




chrX_-_153210107 0.004 ENST00000369997.3
ENST00000393700.3
ENST00000412763.1
 RENBP


renin binding protein


chr10_+_64893039 0.003 ENST00000277746.6
ENST00000435510.2
 NRBF2

nuclear receptor binding factor 2

chr15_+_93749295 0.001 ENST00000599897.1
 AC112693.2
AC112693.2
chr8_-_16043780 0.001 ENST00000445506.2
 MSR1
macrophage scavenger receptor 1
chr8_-_82443613 0.001 ENST00000360464.4
 FABP12
fatty acid binding protein 12
chr3_-_184971817 0.000 ENST00000440662.1
ENST00000456310.1
 EHHADH

enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase

chr12_+_83080659 0.000 ENST00000321196.3
 TMTC2
transmembrane and tetratricopeptide repeat containing 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:1990619 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) histone H3-K9 deacetylation(GO:1990619)
0.0 0.1 GO:0016078 tRNA catabolic process(GO:0016078)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.0 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.1 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.1 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0 0.1 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.3 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.0 GO:0033677 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677) triplex DNA binding(GO:0045142)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)