Motif ID: ZBTB3

Z-value: 0.335


Transcription factors associated with ZBTB3:

Gene SymbolEntrez IDGene Name
ZBTB3 ENSG00000185670.7 ZBTB3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZBTB3hg19_v2_chr11_-_62521614_62521660-0.068.7e-01Click!


Activity profile for motif ZBTB3.

activity profile for motif ZBTB3


Sorted Z-values histogram for motif ZBTB3

Sorted Z-values for motif ZBTB3



Network of associatons between targets according to the STRING database.



First level regulatory network of ZBTB3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_33709268 0.330 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
 SLC39A6


solute carrier family 39 (zinc transporter), member 6


chr18_+_32073253 0.284 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
 DTNA


dystrobrevin, alpha


chr6_+_30850697 0.190 ENST00000509639.1
ENST00000412274.2
ENST00000507901.1
ENST00000507046.1
ENST00000437124.2
ENST00000454612.2
ENST00000396342.2
 DDR1






discoidin domain receptor tyrosine kinase 1






chr3_-_149688655 0.177 ENST00000461930.1
ENST00000423691.2
ENST00000490975.1
ENST00000461868.1
ENST00000452853.2
 PFN2




profilin 2




chr1_-_32801825 0.155 ENST00000329421.7
 MARCKSL1
MARCKS-like 1
chr7_+_16793160 0.149 ENST00000262067.4
 TSPAN13
tetraspanin 13
chr10_+_99332198 0.145 ENST00000307518.5
ENST00000298808.5
ENST00000370655.1
 ANKRD2


ankyrin repeat domain 2 (stretch responsive muscle)


chr4_-_140216948 0.144 ENST00000265500.4
 NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr6_+_30850862 0.142 ENST00000504651.1
ENST00000512694.1
ENST00000515233.1
 DDR1


discoidin domain receptor tyrosine kinase 1


chr4_-_17783135 0.140 ENST00000265018.3
 FAM184B
family with sequence similarity 184, member B
chr5_+_76506706 0.140 ENST00000340978.3
ENST00000346042.3
ENST00000264917.5
ENST00000342343.4
ENST00000333194.4
 PDE8B




phosphodiesterase 8B




chr13_+_27998681 0.137 ENST00000381140.4
 GTF3A
general transcription factor IIIA
chr11_-_67980744 0.129 ENST00000401547.2
ENST00000453170.1
ENST00000304363.4
 SUV420H1


suppressor of variegation 4-20 homolog 1 (Drosophila)


chr17_-_5487768 0.127 ENST00000269280.4
ENST00000345221.3
ENST00000262467.5
 NLRP1


NLR family, pyrin domain containing 1


chr10_-_105156198 0.114 ENST00000369815.1
ENST00000309579.3
ENST00000337003.4
 USMG5


up-regulated during skeletal muscle growth 5 homolog (mouse)


chr11_+_82783097 0.114 ENST00000501011.2
ENST00000527627.1
ENST00000526795.1
ENST00000533528.1
ENST00000533708.1
ENST00000534499.1
 RAB30-AS1





RAB30 antisense RNA 1 (head to head)





chr9_-_34637718 0.108 ENST00000378892.1
ENST00000277010.4
 SIGMAR1

sigma non-opioid intracellular receptor 1

chr15_+_64428529 0.107 ENST00000560861.1
 SNX1
sorting nexin 1
chr12_-_120241187 0.104 ENST00000392520.2
 CIT
citron (rho-interacting, serine/threonine kinase 21)
chr11_-_82782861 0.101 ENST00000524635.1
ENST00000526205.1
ENST00000527633.1
ENST00000533486.1
ENST00000533276.2
 RAB30




RAB30, member RAS oncogene family




chr6_+_30851205 0.100 ENST00000515881.1
 DDR1
discoidin domain receptor tyrosine kinase 1
chr17_-_56595196 0.097 ENST00000579921.1
ENST00000579925.1
ENST00000323456.5
 MTMR4


myotubularin related protein 4


chr14_-_92413727 0.095 ENST00000267620.10
 FBLN5
fibulin 5
chr14_-_92414055 0.090 ENST00000342058.4
 FBLN5
fibulin 5
chr11_-_82782952 0.087 ENST00000534141.1
 RAB30
RAB30, member RAS oncogene family
chr3_-_149688502 0.087 ENST00000481767.1
ENST00000475518.1
 PFN2

profilin 2

chr16_+_24266874 0.084 ENST00000005284.3
 CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr7_+_134576151 0.081 ENST00000393118.2
 CALD1
caldesmon 1
chr14_-_92413353 0.080 ENST00000556154.1
 FBLN5
fibulin 5
chr11_-_18548426 0.074 ENST00000357193.3
ENST00000536719.1
 TSG101

tumor susceptibility 101

chr12_-_10022735 0.073 ENST00000228438.2
 CLEC2B
C-type lectin domain family 2, member B
chr2_-_25565377 0.071 ENST00000264709.3
ENST00000406659.3
 DNMT3A

DNA (cytosine-5-)-methyltransferase 3 alpha

chr14_-_90085458 0.068 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
 FOXN3


forkhead box N3


chr2_+_42396472 0.065 ENST00000318522.5
ENST00000402711.2
 EML4

echinoderm microtubule associated protein like 4

chr6_-_31940065 0.064 ENST00000375349.3
ENST00000337523.5
 DXO

decapping exoribonuclease

chr17_+_75123947 0.063 ENST00000586429.1
 SEC14L1
SEC14-like 1 (S. cerevisiae)
chr9_+_74526532 0.061 ENST00000486911.2
 C9orf85
chromosome 9 open reading frame 85
chr2_+_42396574 0.061 ENST00000401738.3
 EML4
echinoderm microtubule associated protein like 4
chr4_-_73935409 0.061 ENST00000507544.2
ENST00000295890.4
 COX18

COX18 cytochrome C oxidase assembly factor

chr19_-_49496557 0.060 ENST00000323798.3
ENST00000541188.1
ENST00000544287.1
ENST00000540532.1
ENST00000263276.6
 GYS1




glycogen synthase 1 (muscle)




chr1_+_65210772 0.059 ENST00000371072.4
ENST00000294428.3
 RAVER2

ribonucleoprotein, PTB-binding 2

chr5_-_94417339 0.058 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
 MCTP1


multiple C2 domains, transmembrane 1


chr4_+_159236462 0.056 ENST00000460056.2
 RXFP1
relaxin/insulin-like family peptide receptor 1
chr3_-_149688896 0.056 ENST00000239940.7
 PFN2
profilin 2
chr3_+_139063372 0.056 ENST00000478464.1
 MRPS22
mitochondrial ribosomal protein S22
chr3_+_139062838 0.054 ENST00000310776.4
ENST00000465056.1
ENST00000465373.1
 MRPS22


mitochondrial ribosomal protein S22


chr10_-_76868931 0.052 ENST00000372700.3
ENST00000473072.2
ENST00000491677.2
ENST00000607131.1
ENST00000372702.3
 DUSP13




dual specificity phosphatase 13




chr11_-_14913765 0.050 ENST00000334636.5
 CYP2R1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr6_-_31939734 0.050 ENST00000375356.3
 DXO
decapping exoribonuclease
chr7_+_134576317 0.048 ENST00000424922.1
ENST00000495522.1
 CALD1

caldesmon 1

chr5_+_170288856 0.046 ENST00000523189.1
 RANBP17
RAN binding protein 17
chr14_+_60715928 0.046 ENST00000395076.4
 PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr2_-_74570520 0.045 ENST00000394019.2
ENST00000346834.4
ENST00000359484.4
ENST00000423644.1
ENST00000377634.4
ENST00000436454.1
 SLC4A5





solute carrier family 4 (sodium bicarbonate cotransporter), member 5





chr2_+_88824161 0.043 ENST00000303254.3
 TEX37
testis expressed 37
chr16_+_53164956 0.043 ENST00000563410.1
 CHD9
chromodomain helicase DNA binding protein 9
chrX_-_118827333 0.043 ENST00000360156.7
ENST00000354228.4
ENST00000489216.1
ENST00000354416.3
ENST00000394610.1
ENST00000343984.5
 SEPT6





septin 6





chr19_-_6670128 0.043 ENST00000245912.3
 TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr1_-_166136187 0.042 ENST00000338353.3
 FAM78B
family with sequence similarity 78, member B
chr2_-_154335300 0.041 ENST00000325926.3
 RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr12_+_54718904 0.041 ENST00000262061.2
ENST00000549043.1
ENST00000552218.1
ENST00000553231.1
ENST00000552362.1
ENST00000455864.2
ENST00000416254.2
ENST00000549116.1
ENST00000551779.1
 COPZ1








coatomer protein complex, subunit zeta 1








chr6_+_123100853 0.038 ENST00000356535.4
 FABP7
fatty acid binding protein 7, brain
chr7_+_100081542 0.037 ENST00000300179.2
ENST00000423930.1
 NYAP1

neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1

chrX_+_70364667 0.036 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
 NLGN3



neuroligin 3



chr5_+_138609441 0.036 ENST00000509990.1
ENST00000506147.1
ENST00000512107.1
 MATR3


matrin 3


chr5_-_115177247 0.035 ENST00000500945.2
 ATG12
autophagy related 12
chr1_+_211433275 0.033 ENST00000367005.4
 RCOR3
REST corepressor 3
chr10_-_76868866 0.033 ENST00000607487.1
 DUSP13
dual specificity phosphatase 13
chrX_+_134166333 0.032 ENST00000257013.7
 FAM127A
family with sequence similarity 127, member A
chr20_+_54987305 0.032 ENST00000371336.3
ENST00000434344.1
 CASS4

Cas scaffolding protein family member 4

chr19_-_39926268 0.029 ENST00000599705.1
 RPS16
ribosomal protein S16
chr19_-_40023450 0.026 ENST00000326282.4
 EID2B
EP300 interacting inhibitor of differentiation 2B
chr17_+_33895090 0.026 ENST00000592381.1
 RP11-1094M14.11
RP11-1094M14.11
chrX_+_23801280 0.025 ENST00000379251.3
ENST00000379253.3
ENST00000379254.1
ENST00000379270.4
 SAT1



spermidine/spermine N1-acetyltransferase 1



chrX_-_154563889 0.025 ENST00000369449.2
ENST00000321926.4
 CLIC2

chloride intracellular channel 2

chr19_-_45657028 0.023 ENST00000429338.1
ENST00000589776.1
 NKPD1

NTPase, KAP family P-loop domain containing 1

chr7_-_38394118 0.022 ENST00000390345.2
 TRGV4
T cell receptor gamma variable 4
chr6_-_41122063 0.022 ENST00000426005.2
ENST00000437044.2
ENST00000373127.4
 TREML1


triggering receptor expressed on myeloid cells-like 1


chr17_+_61554829 0.020 ENST00000582627.1
 ACE
angiotensin I converting enzyme
chr1_+_210001309 0.020 ENST00000491415.2
 DIEXF
digestive organ expansion factor homolog (zebrafish)
chr4_+_166300084 0.018 ENST00000402744.4
 CPE
carboxypeptidase E
chr17_+_7531281 0.017 ENST00000575729.1
ENST00000340624.5
 SHBG

sex hormone-binding globulin

chr1_-_169555779 0.017 ENST00000367797.3
ENST00000367796.3
 F5

coagulation factor V (proaccelerin, labile factor)

chr1_-_155270770 0.016 ENST00000392414.3
 PKLR
pyruvate kinase, liver and RBC
chr10_+_50817141 0.016 ENST00000339797.1
 CHAT
choline O-acetyltransferase
chr5_+_115177178 0.016 ENST00000316788.7
 AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr9_+_96717821 0.015 ENST00000454594.1
 RP11-231K24.2
RP11-231K24.2
chr4_+_48492269 0.015 ENST00000327939.4
 ZAR1
zygote arrest 1
chr17_+_46018872 0.015 ENST00000583599.1
ENST00000434554.2
ENST00000225573.4
ENST00000544840.1
ENST00000534893.1
 PNPO




pyridoxamine 5'-phosphate oxidase




chr5_-_94417186 0.014 ENST00000312216.8
ENST00000512425.1
 MCTP1

multiple C2 domains, transmembrane 1

chr3_-_195163584 0.013 ENST00000439666.1
 ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr2_+_202899310 0.013 ENST00000286201.1
 FZD7
frizzled family receptor 7
chr6_+_12958137 0.013 ENST00000457702.2
ENST00000379345.2
 PHACTR1

phosphatase and actin regulator 1

chr9_+_133259836 0.013 ENST00000455439.2
 HMCN2
hemicentin 2
chr6_+_44126545 0.012 ENST00000532171.1
ENST00000398776.1
ENST00000542245.1
 CAPN11


calpain 11


chr5_+_75378997 0.012 ENST00000502798.2
 SV2C
synaptic vesicle glycoprotein 2C
chr13_-_48612067 0.012 ENST00000543413.1
 SUCLA2
succinate-CoA ligase, ADP-forming, beta subunit
chr16_-_19896150 0.011 ENST00000570142.1
 GPRC5B
G protein-coupled receptor, family C, group 5, member B
chr17_+_72983674 0.011 ENST00000337231.5
 CDR2L
cerebellar degeneration-related protein 2-like
chr5_+_75379224 0.011 ENST00000322285.7
 SV2C
synaptic vesicle glycoprotein 2C
chr17_-_39623681 0.010 ENST00000225899.3
 KRT32
keratin 32
chr5_-_149669612 0.010 ENST00000510347.1
 CAMK2A
calcium/calmodulin-dependent protein kinase II alpha
chrX_+_69454505 0.009 ENST00000374521.3
 AWAT1
acyl-CoA wax alcohol acyltransferase 1
chr5_-_94417562 0.009 ENST00000505465.1
 MCTP1
multiple C2 domains, transmembrane 1
chr2_-_136594740 0.009 ENST00000264162.2
 LCT
lactase
chr16_+_89787393 0.009 ENST00000289816.5
ENST00000568064.1
 ZNF276

zinc finger protein 276

chr19_+_52848659 0.009 ENST00000327920.8
 ZNF610
zinc finger protein 610
chr5_+_140514782 0.009 ENST00000231134.5
 PCDHB5
protocadherin beta 5
chr8_+_42196000 0.009 ENST00000518925.1
ENST00000538005.1
 POLB

polymerase (DNA directed), beta

chr12_-_52887034 0.008 ENST00000330722.6
 KRT6A
keratin 6A
chr19_-_55549624 0.008 ENST00000417454.1
ENST00000310373.3
ENST00000333884.2
 GP6


glycoprotein VI (platelet)


chr18_+_42260059 0.008 ENST00000426838.4
 SETBP1
SET binding protein 1
chr4_-_7436671 0.008 ENST00000319098.4
 PSAPL1
prosaposin-like 1 (gene/pseudogene)
chr16_-_68406161 0.008 ENST00000568373.1
ENST00000563226.1
 SMPD3

sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)

chr5_+_112074029 0.007 ENST00000512211.2
 APC
adenomatous polyposis coli
chr6_+_123100620 0.006 ENST00000368444.3
 FABP7
fatty acid binding protein 7, brain
chr7_+_120716625 0.005 ENST00000443817.1
 CPED1
cadherin-like and PC-esterase domain containing 1
chr11_+_73661364 0.005 ENST00000339764.1
 DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr22_+_31460091 0.005 ENST00000432777.1
ENST00000422839.1
 SMTN

smoothelin

chr19_-_2042065 0.005 ENST00000591588.1
ENST00000591142.1
 MKNK2

MAP kinase interacting serine/threonine kinase 2

chr3_-_195163803 0.004 ENST00000326793.6
 ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr20_+_54987168 0.003 ENST00000360314.3
 CASS4
Cas scaffolding protein family member 4
chrX_+_11776278 0.003 ENST00000312196.4
ENST00000337339.2
 MSL3

male-specific lethal 3 homolog (Drosophila)

chr9_+_72002837 0.002 ENST00000377216.3
 FAM189A2
family with sequence similarity 189, member A2
chr4_-_5894777 0.001 ENST00000324989.7
 CRMP1
collapsin response mediator protein 1
chr1_+_159141397 0.001 ENST00000368124.4
ENST00000368125.4
ENST00000416746.1
 CADM3


cell adhesion molecule 3



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.0 0.1 GO:2000395 positive regulation of viral budding via host ESCRT complex(GO:1903774) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.2 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.1 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.1 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.0 GO:0032173 septin ring(GO:0005940) septin collar(GO:0032173)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)