Motif ID: VENTX

Z-value: 0.268


Transcription factors associated with VENTX:

Gene SymbolEntrez IDGene Name
VENTX ENSG00000151650.7 VENTX

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
VENTXhg19_v2_chr10_+_135050908_135050908-0.402.9e-01Click!


Activity profile for motif VENTX.

activity profile for motif VENTX


Sorted Z-values histogram for motif VENTX

Sorted Z-values for motif VENTX



Network of associatons between targets according to the STRING database.



First level regulatory network of VENTX

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_123430948 0.430 ENST00000529432.1
ENST00000534764.1
 GRAMD1B

GRAM domain containing 1B

chr6_+_12290586 0.346 ENST00000379375.5
 EDN1
endothelin 1
chrX_-_153602991 0.261 ENST00000369850.3
ENST00000422373.1
 FLNA

filamin A, alpha

chr13_+_110958124 0.166 ENST00000400163.2
 COL4A2
collagen, type IV, alpha 2
chr13_+_76378407 0.164 ENST00000447038.1
 LMO7
LIM domain 7
chr22_+_39101728 0.157 ENST00000216044.5
ENST00000484657.1
 GTPBP1

GTP binding protein 1

chr11_+_35198118 0.157 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
 CD44



CD44 molecule (Indian blood group)



chr13_+_76378357 0.155 ENST00000489941.2
ENST00000525373.1
 LMO7

LIM domain 7

chr13_+_76378305 0.153 ENST00000526371.1
ENST00000526528.1
 LMO7

LIM domain 7

chr4_-_84035905 0.139 ENST00000311507.4
 PLAC8
placenta-specific 8
chr4_-_84035868 0.136 ENST00000426923.2
ENST00000509973.1
 PLAC8

placenta-specific 8

chr6_+_126221034 0.131 ENST00000433571.1
 NCOA7
nuclear receptor coactivator 7
chr2_+_149402989 0.127 ENST00000397424.2
 EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr6_-_138820624 0.118 ENST00000343505.5
 NHSL1
NHS-like 1
chr2_+_226265364 0.118 ENST00000272907.6
 NYAP2
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chrX_-_46187069 0.115 ENST00000446884.1
 RP1-30G7.2
RP1-30G7.2
chr11_+_46722368 0.115 ENST00000311764.2
 ZNF408
zinc finger protein 408
chr6_+_34204642 0.114 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
 HMGA1




high mobility group AT-hook 1




chr11_-_3859089 0.110 ENST00000396979.1
 RHOG
ras homolog family member G
chr19_+_48949087 0.109 ENST00000598711.1
 GRWD1
glutamate-rich WD repeat containing 1
chr3_+_50211240 0.107 ENST00000420831.1
 SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr7_-_104909435 0.096 ENST00000357311.3
 SRPK2
SRSF protein kinase 2
chr12_+_27398584 0.095 ENST00000543246.1
 STK38L
serine/threonine kinase 38 like
chr10_-_28571015 0.092 ENST00000375719.3
ENST00000375732.1
 MPP7

membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)

chr17_+_43239231 0.088 ENST00000591576.1
ENST00000591070.1
ENST00000592695.1
 HEXIM2


hexamethylene bis-acetamide inducible 2


chr14_-_82000140 0.084 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
 SEL1L


sel-1 suppressor of lin-12-like (C. elegans)


chr17_+_17685422 0.084 ENST00000395774.1
 RAI1
retinoic acid induced 1
chr4_+_129732419 0.079 ENST00000510308.1
 PHF17
jade family PHD finger 1
chr11_-_18211042 0.079 ENST00000527671.1
 RP11-113D6.6
Uncharacterized protein
chr1_+_41174988 0.078 ENST00000372652.1
 NFYC
nuclear transcription factor Y, gamma
chr22_+_42834029 0.074 ENST00000428765.1
 CTA-126B4.7
CTA-126B4.7
chr1_+_43291220 0.070 ENST00000372514.3
 ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chr1_+_150337144 0.065 ENST00000539519.1
ENST00000369067.3
ENST00000369068.4
 RPRD2


regulation of nuclear pre-mRNA domain containing 2


chr1_+_162351503 0.065 ENST00000458626.2
 C1orf226
chromosome 1 open reading frame 226
chr5_-_142780280 0.065 ENST00000424646.2
 NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr19_+_48949030 0.063 ENST00000253237.5
 GRWD1
glutamate-rich WD repeat containing 1
chr17_-_29645836 0.058 ENST00000578584.1
 CTD-2370N5.3
CTD-2370N5.3
chr20_-_50722183 0.056 ENST00000371523.4
 ZFP64
ZFP64 zinc finger protein
chr1_-_95391315 0.054 ENST00000545882.1
ENST00000415017.1
 CNN3

calponin 3, acidic

chr3_-_9834463 0.054 ENST00000439043.1
 TADA3
transcriptional adaptor 3
chr1_-_232651312 0.054 ENST00000262861.4
 SIPA1L2
signal-induced proliferation-associated 1 like 2
chr12_-_89746264 0.053 ENST00000548755.1
 DUSP6
dual specificity phosphatase 6
chr6_-_32157947 0.051 ENST00000375050.4
 PBX2
pre-B-cell leukemia homeobox 2
chr17_-_202579 0.049 ENST00000577079.1
ENST00000331302.7
ENST00000536489.2
 RPH3AL


rabphilin 3A-like (without C2 domains)


chr10_+_94594351 0.049 ENST00000371552.4
 EXOC6
exocyst complex component 6
chr18_+_55888767 0.046 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
 NEDD4L


neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase


chr8_-_42358742 0.044 ENST00000517366.1
 SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr16_+_14280742 0.044 ENST00000341243.5
 MKL2
MKL/myocardin-like 2
chr6_-_111927062 0.044 ENST00000359831.4
 TRAF3IP2
TRAF3 interacting protein 2
chr10_+_24738355 0.043 ENST00000307544.6
 KIAA1217
KIAA1217
chr1_-_178840157 0.043 ENST00000367629.1
ENST00000234816.2
 ANGPTL1

angiopoietin-like 1

chr17_-_48785216 0.042 ENST00000285243.6
 ANKRD40
ankyrin repeat domain 40
chr3_+_177159695 0.042 ENST00000442937.1
 LINC00578
long intergenic non-protein coding RNA 578
chr1_+_168250194 0.041 ENST00000367821.3
 TBX19
T-box 19
chr2_-_88285309 0.039 ENST00000420840.2
 RGPD2
RANBP2-like and GRIP domain containing 2
chr14_+_65170820 0.039 ENST00000555982.1
 PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr2_-_166060382 0.038 ENST00000409101.3
 SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr11_-_11374904 0.037 ENST00000528848.2
 CSNK2A3
casein kinase 2, alpha 3 polypeptide
chr3_+_156799587 0.036 ENST00000469196.1
 RP11-6F2.5
RP11-6F2.5
chr6_-_111927449 0.033 ENST00000368761.5
ENST00000392556.4
ENST00000340026.6
 TRAF3IP2


TRAF3 interacting protein 2


chr12_-_86650077 0.033 ENST00000552808.2
ENST00000547225.1
 MGAT4C

mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)

chr11_-_64684672 0.033 ENST00000377264.3
ENST00000421419.2
 ATG2A

autophagy related 2A

chr2_+_87135076 0.033 ENST00000409776.2
 RGPD1
RANBP2-like and GRIP domain containing 1
chr4_-_105416039 0.032 ENST00000394767.2
 CXXC4
CXXC finger protein 4
chr19_-_46088068 0.032 ENST00000263275.4
ENST00000323060.3
 OPA3

optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)

chr12_-_122018346 0.030 ENST00000377069.4
 KDM2B
lysine (K)-specific demethylase 2B
chr3_+_9834179 0.029 ENST00000498623.2
 ARPC4
actin related protein 2/3 complex, subunit 4, 20kDa
chr6_+_37897735 0.028 ENST00000373389.5
 ZFAND3
zinc finger, AN1-type domain 3
chr6_+_155538093 0.027 ENST00000462408.2
 TIAM2
T-cell lymphoma invasion and metastasis 2
chr17_+_39845134 0.027 ENST00000591776.1
ENST00000469257.1
 EIF1

eukaryotic translation initiation factor 1

chr3_+_171561127 0.027 ENST00000334567.5
ENST00000450693.1
 TMEM212

transmembrane protein 212

chr11_-_107729287 0.027 ENST00000375682.4
 SLC35F2
solute carrier family 35, member F2
chr3_+_9834227 0.027 ENST00000287613.7
ENST00000397261.3
 ARPC4

actin related protein 2/3 complex, subunit 4, 20kDa

chr13_-_30683005 0.026 ENST00000413591.1
ENST00000432770.1
 LINC00365

long intergenic non-protein coding RNA 365

chr12_+_52695617 0.026 ENST00000293525.5
 KRT86
keratin 86
chr11_-_107729887 0.026 ENST00000525815.1
 SLC35F2
solute carrier family 35, member F2
chr2_-_165698521 0.025 ENST00000409184.3
ENST00000392717.2
ENST00000456693.1
 COBLL1


cordon-bleu WH2 repeat protein-like 1


chr7_+_141408153 0.025 ENST00000397541.2
 WEE2
WEE1 homolog 2 (S. pombe)
chr3_+_32859510 0.025 ENST00000383763.5
 TRIM71
tripartite motif containing 71, E3 ubiquitin protein ligase
chr14_+_65453432 0.025 ENST00000246166.2
 FNTB
farnesyltransferase, CAAX box, beta
chr11_-_107729504 0.024 ENST00000265836.7
 SLC35F2
solute carrier family 35, member F2
chr1_+_78470530 0.024 ENST00000370763.5
 DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr1_+_150337100 0.023 ENST00000401000.4
 RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr12_-_52828147 0.022 ENST00000252245.5
 KRT75
keratin 75
chr2_-_165698662 0.022 ENST00000194871.6
ENST00000445474.2
 COBLL1

cordon-bleu WH2 repeat protein-like 1

chr1_-_144994909 0.021 ENST00000369347.4
ENST00000369354.3
 PDE4DIP

phosphodiesterase 4D interacting protein

chr6_-_97731019 0.020 ENST00000275053.4
 MMS22L
MMS22-like, DNA repair protein
chr7_+_90338547 0.019 ENST00000446790.1
 CDK14
cyclin-dependent kinase 14
chr2_-_164592497 0.019 ENST00000333129.3
ENST00000409634.1
 FIGN

fidgetin

chr4_+_169418255 0.018 ENST00000505667.1
ENST00000511948.1
 PALLD

palladin, cytoskeletal associated protein

chr2_+_203776937 0.018 ENST00000402905.3
ENST00000414490.1
ENST00000431787.1
ENST00000444724.1
ENST00000414857.1
ENST00000430899.1
ENST00000445120.1
ENST00000441569.1
ENST00000432024.1
ENST00000443740.1
ENST00000414439.1
ENST00000428585.1
ENST00000545253.1
ENST00000545262.1
ENST00000447539.1
ENST00000456821.2
ENST00000434998.1
ENST00000320443.8
 CARF

















calcium responsive transcription factor

















chr1_+_244515930 0.017 ENST00000366537.1
ENST00000308105.4
 C1orf100

chromosome 1 open reading frame 100

chr4_+_169013666 0.016 ENST00000359299.3
 ANXA10
annexin A10
chr7_+_18535346 0.016 ENST00000405010.3
ENST00000406451.4
ENST00000428307.2
 HDAC9


histone deacetylase 9


chr7_+_90338712 0.016 ENST00000265741.3
ENST00000406263.1
 CDK14

cyclin-dependent kinase 14

chr8_+_31496809 0.016 ENST00000518104.1
ENST00000519301.1
 NRG1

neuregulin 1

chr16_+_14280564 0.015 ENST00000572567.1
 MKL2
MKL/myocardin-like 2
chr4_+_129732467 0.015 ENST00000413543.2
 PHF17
jade family PHD finger 1
chr2_+_171034646 0.015 ENST00000409044.3
ENST00000408978.4
 MYO3B

myosin IIIB

chr6_-_139613269 0.015 ENST00000358430.3
 TXLNB
taxilin beta
chr8_+_92261516 0.015 ENST00000276609.3
ENST00000309536.2
 SLC26A7

solute carrier family 26 (anion exchanger), member 7

chr6_-_90529418 0.015 ENST00000439638.1
ENST00000369393.3
ENST00000428876.1
 MDN1


MDN1, midasin homolog (yeast)


chr5_+_43121698 0.015 ENST00000505606.2
ENST00000509634.1
ENST00000509341.1
 ZNF131


zinc finger protein 131


chrX_+_78003204 0.014 ENST00000435339.3
ENST00000514744.1
 LPAR4

lysophosphatidic acid receptor 4

chr8_+_97773457 0.013 ENST00000521142.1
 CPQ
carboxypeptidase Q
chr2_+_45168875 0.013 ENST00000260653.3
 SIX3
SIX homeobox 3
chr10_+_74451883 0.013 ENST00000373053.3
ENST00000357157.6
 MCU

mitochondrial calcium uniporter

chr2_-_224467002 0.012 ENST00000421386.1
ENST00000433889.1
 SCG2

secretogranin II

chr8_+_97773202 0.012 ENST00000519484.1
 CPQ
carboxypeptidase Q
chr4_-_176733377 0.012 ENST00000505375.1
 GPM6A
glycoprotein M6A
chr12_-_94673956 0.011 ENST00000551941.1
 RP11-1105G2.3
Uncharacterized protein
chr21_+_39644395 0.011 ENST00000398934.1
 KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr6_-_76203454 0.010 ENST00000237172.7
 FILIP1
filamin A interacting protein 1
chrY_-_13524717 0.009 ENST00000331172.6
 SLC9B1P1
solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1 pseudogene 1
chr12_-_16758059 0.009 ENST00000261169.6
 LMO3
LIM domain only 3 (rhombotin-like 2)
chr6_+_140175987 0.009 ENST00000414038.1
ENST00000431609.1
 RP5-899B16.1

RP5-899B16.1

chr12_-_6233828 0.009 ENST00000572068.1
ENST00000261405.5
 VWF

von Willebrand factor

chr22_-_40929812 0.009 ENST00000422851.1
 MKL1
megakaryoblastic leukemia (translocation) 1
chr3_+_130569429 0.009 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
 ATP2C1



ATPase, Ca++ transporting, type 2C, member 1



chr1_-_67600639 0.008 ENST00000544837.1
ENST00000603691.1
 C1orf141

chromosome 1 open reading frame 141

chr5_-_124081008 0.008 ENST00000306315.5
 ZNF608
zinc finger protein 608
chr12_+_70219052 0.008 ENST00000552032.2
ENST00000547771.2
 MYRFL

myelin regulatory factor-like

chr12_-_53994805 0.008 ENST00000328463.7
 ATF7
activating transcription factor 7
chr5_+_61874562 0.007 ENST00000409534.1
ENST00000334994.5
 IPO11
LRRC70
importin 11
leucine rich repeat containing 70
chr4_+_123161120 0.007 ENST00000446180.1
 KIAA1109
KIAA1109
chr14_+_23709555 0.006 ENST00000430154.2
 C14orf164
chromosome 14 open reading frame 164
chr9_+_109685630 0.006 ENST00000451160.2
 RP11-508N12.4
Uncharacterized protein
chr7_+_18535321 0.006 ENST00000413380.1
ENST00000430454.1
 HDAC9

histone deacetylase 9

chr2_-_145188137 0.006 ENST00000440875.1
 ZEB2
zinc finger E-box binding homeobox 2
chr6_+_152011628 0.006 ENST00000404742.1
ENST00000440973.1
 ESR1

estrogen receptor 1

chr4_+_71384300 0.006 ENST00000504451.1
 AMTN
amelotin
chr10_-_56561022 0.005 ENST00000373965.2
ENST00000414778.1
ENST00000395438.1
ENST00000409834.1
ENST00000395445.1
ENST00000395446.1
ENST00000395442.1
ENST00000395440.1
ENST00000395432.2
ENST00000361849.3
ENST00000395433.1
ENST00000320301.6
ENST00000395430.1
ENST00000437009.1
 PCDH15













protocadherin-related 15













chr9_+_2159850 0.005 ENST00000416751.1
 SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr8_+_38831683 0.005 ENST00000302495.4
 HTRA4
HtrA serine peptidase 4
chr1_+_62439037 0.005 ENST00000545929.1
 INADL
InaD-like (Drosophila)
chr6_+_78400375 0.004 ENST00000602452.2
 MEI4
meiosis-specific 4 homolog (S. cerevisiae)
chr4_+_169418195 0.004 ENST00000261509.6
ENST00000335742.7
 PALLD

palladin, cytoskeletal associated protein

chr14_+_65171315 0.004 ENST00000394691.1
 PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr2_+_177015122 0.004 ENST00000468418.3
 HOXD3
homeobox D3
chr12_+_126107042 0.004 ENST00000535886.1
 TMEM132B
transmembrane protein 132B
chr15_+_34260921 0.003 ENST00000560035.1
 CHRM5
cholinergic receptor, muscarinic 5
chr7_+_129984630 0.003 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
 CPA5








carboxypeptidase A5








chr12_-_16430619 0.003 ENST00000344941.3
 SLC15A5
solute carrier family 15, member 5
chr12_+_8666126 0.002 ENST00000299665.2
 CLEC4D
C-type lectin domain family 4, member D
chr7_-_78400598 0.002 ENST00000536571.1
 MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr12_-_45269251 0.002 ENST00000553120.1
 NELL2
NEL-like 2 (chicken)
chr4_+_71384257 0.002 ENST00000339336.4
 AMTN
amelotin
chr17_-_10372875 0.002 ENST00000255381.2
 MYH4
myosin, heavy chain 4, skeletal muscle
chr3_-_57260377 0.001 ENST00000495160.2
 HESX1
HESX homeobox 1
chr6_+_53964336 0.001 ENST00000447836.2
ENST00000511678.1
 MLIP

muscular LMNA-interacting protein

chr2_+_166152283 0.001 ENST00000375427.2
 SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr3_-_57233966 0.000 ENST00000473921.1
ENST00000295934.3
 HESX1

HESX homeobox 1

chr1_+_40713573 0.000 ENST00000372766.3
 TMCO2
transmembrane and coiled-coil domains 2
chr4_+_86525299 0.000 ENST00000512201.1
 ARHGAP24
Rho GTPase activating protein 24

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.3 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.1 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.2 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.3 GO:0031523 Myb complex(GO:0031523)
0.0 0.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection