Motif ID: VDR

Z-value: 1.038


Transcription factors associated with VDR:

Gene SymbolEntrez IDGene Name
VDR ENSG00000111424.6 VDR

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
VDRhg19_v2_chr12_-_48298785_482988280.891.5e-03Click!


Activity profile for motif VDR.

activity profile for motif VDR


Sorted Z-values histogram for motif VDR

Sorted Z-values for motif VDR



Network of associatons between targets according to the STRING database.



First level regulatory network of VDR

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_183559693 3.991 ENST00000367535.3
ENST00000413720.1
ENST00000418089.1
NCF2


neutrophil cytosolic factor 2


chr2_+_102928009 2.044 ENST00000404917.2
ENST00000447231.1
IL1RL1

interleukin 1 receptor-like 1

chr6_+_31916733 1.977 ENST00000483004.1
CFB
complement factor B
chr11_-_60719213 1.582 ENST00000227880.3
SLC15A3
solute carrier family 15 (oligopeptide transporter), member 3
chr7_-_92777606 1.243 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L






sterile alpha motif domain containing 9-like






chr10_+_104154229 1.161 ENST00000428099.1
ENST00000369966.3
NFKB2

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

chr16_-_75282088 0.924 ENST00000542031.2
BCAR1
breast cancer anti-estrogen resistance 1
chr17_-_79791118 0.895 ENST00000576431.1
ENST00000575061.1
ENST00000455127.2
ENST00000572645.1
ENST00000538396.1
ENST00000573478.1
FAM195B





family with sequence similarity 195, member B





chr11_-_65667884 0.844 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1


FOS-like antigen 1


chr8_-_145028013 0.827 ENST00000354958.2
PLEC
plectin
chr11_-_65667997 0.815 ENST00000312562.2
ENST00000534222.1
FOSL1

FOS-like antigen 1

chr16_-_2770216 0.768 ENST00000302641.3
PRSS27
protease, serine 27
chr12_+_52626898 0.752 ENST00000331817.5
KRT7
keratin 7
chr6_+_112668524 0.713 ENST00000441065.2
RFPL4B
ret finger protein-like 4B
chr1_-_221915418 0.668 ENST00000323825.3
ENST00000366899.3
DUSP10

dual specificity phosphatase 10

chr5_-_147211226 0.659 ENST00000296695.5
SPINK1
serine peptidase inhibitor, Kazal type 1
chr22_-_29663954 0.635 ENST00000216085.7
RHBDD3
rhomboid domain containing 3
chr9_-_115095229 0.626 ENST00000210227.4
PTBP3
polypyrimidine tract binding protein 3
chr7_-_105029812 0.620 ENST00000482897.1
SRPK2
SRSF protein kinase 2
chr14_-_35873856 0.592 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA


nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha


chr6_-_42016385 0.584 ENST00000502771.1
ENST00000508143.1
ENST00000514588.1
ENST00000510503.1
ENST00000415497.2
ENST00000372988.4
CCND3





cyclin D3





chr22_+_31199037 0.559 ENST00000424224.1
OSBP2
oxysterol binding protein 2
chr12_+_3068957 0.535 ENST00000543035.1
TEAD4
TEA domain family member 4
chr19_+_56653064 0.521 ENST00000593100.1
ZNF444
zinc finger protein 444
chr4_-_23735183 0.510 ENST00000507666.1
RP11-380P13.2
RP11-380P13.2
chr8_-_22926526 0.482 ENST00000347739.3
ENST00000542226.1
TNFRSF10B

tumor necrosis factor receptor superfamily, member 10b

chr19_+_54368001 0.468 ENST00000422045.1
AC008440.10
AC008440.10
chr21_+_43934633 0.465 ENST00000398343.2
SLC37A1
solute carrier family 37 (glucose-6-phosphate transporter), member 1
chr3_-_122283079 0.465 ENST00000471785.1
ENST00000466126.1
PARP9

poly (ADP-ribose) polymerase family, member 9

chr11_+_64126671 0.465 ENST00000530504.1
RPS6KA4
ribosomal protein S6 kinase, 90kDa, polypeptide 4
chr4_+_144434584 0.461 ENST00000283131.3
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr16_-_28936493 0.452 ENST00000544477.1
ENST00000357573.6
RABEP2

rabaptin, RAB GTPase binding effector protein 2

chr11_-_104817919 0.451 ENST00000533252.1
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr7_-_16844611 0.447 ENST00000401412.1
ENST00000419304.2
AGR2

anterior gradient 2

chr11_+_94706804 0.444 ENST00000335080.5
KDM4D
lysine (K)-specific demethylase 4D
chr12_-_25801478 0.443 ENST00000540106.1
ENST00000445693.1
ENST00000545543.1
ENST00000542224.1
IFLTD1



intermediate filament tail domain containing 1



chr22_-_29663690 0.438 ENST00000406335.1
RHBDD3
rhomboid domain containing 3
chr14_-_102771516 0.438 ENST00000524214.1
ENST00000193029.6
ENST00000361847.2
MOK


MOK protein kinase


chr7_+_143078379 0.431 ENST00000449630.1
ENST00000457235.1
ZYX

zyxin

chr17_-_79805146 0.424 ENST00000415593.1
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr8_-_22926623 0.420 ENST00000276431.4
TNFRSF10B
tumor necrosis factor receptor superfamily, member 10b
chr10_+_54074033 0.400 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chrX_+_153770421 0.399 ENST00000369609.5
ENST00000369607.1
IKBKG

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

chr3_-_122283100 0.395 ENST00000492382.1
ENST00000462315.1
PARP9

poly (ADP-ribose) polymerase family, member 9

chr11_-_104840093 0.395 ENST00000417440.2
ENST00000444739.2
CASP4

caspase 4, apoptosis-related cysteine peptidase

chr2_+_87769459 0.386 ENST00000414030.1
ENST00000437561.1
LINC00152

long intergenic non-protein coding RNA 152

chr16_+_31044812 0.385 ENST00000313843.3
STX4
syntaxin 4
chr1_-_27226928 0.376 ENST00000361720.5
GPATCH3
G patch domain containing 3
chr2_-_73511559 0.373 ENST00000521871.1
FBXO41
F-box protein 41
chr11_-_119991589 0.371 ENST00000526881.1
TRIM29
tripartite motif containing 29
chr9_+_138391805 0.366 ENST00000371785.1
MRPS2
mitochondrial ribosomal protein S2
chr16_-_28936007 0.342 ENST00000568703.1
ENST00000567483.1
RABEP2

rabaptin, RAB GTPase binding effector protein 2

chr9_+_131799213 0.341 ENST00000358369.4
ENST00000406926.2
ENST00000277475.5
ENST00000450073.1
FAM73B



family with sequence similarity 73, member B



chr19_+_18530146 0.336 ENST00000348495.6
ENST00000270061.7
SSBP4

single stranded DNA binding protein 4

chr2_+_220363579 0.336 ENST00000313597.5
ENST00000373917.3
ENST00000358215.3
ENST00000373908.1
ENST00000455657.1
ENST00000435316.1
ENST00000341142.3
GMPPA






GDP-mannose pyrophosphorylase A






chr16_-_28937027 0.335 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr11_-_506316 0.333 ENST00000532055.1
ENST00000531540.1
RNH1

ribonuclease/angiogenin inhibitor 1

chr11_+_65154070 0.333 ENST00000317568.5
ENST00000531296.1
ENST00000533782.1
ENST00000355991.5
ENST00000416776.2
ENST00000526201.1
FRMD8





FERM domain containing 8





chr1_-_6550625 0.333 ENST00000377725.1
ENST00000340850.5
PLEKHG5

pleckstrin homology domain containing, family G (with RhoGef domain) member 5

chr12_-_114404111 0.332 ENST00000545145.2
ENST00000392561.3
ENST00000261741.5
RBM19


RNA binding motif protein 19


chr19_+_13261216 0.324 ENST00000587885.1
ENST00000292433.3
IER2

immediate early response 2

chr15_-_42565606 0.322 ENST00000307216.6
ENST00000448392.1
TMEM87A

transmembrane protein 87A

chrX_-_135962923 0.318 ENST00000565438.1
RBMX
RNA binding motif protein, X-linked
chr1_+_2487078 0.314 ENST00000426449.1
ENST00000434817.1
ENST00000435221.2
TNFRSF14


tumor necrosis factor receptor superfamily, member 14


chr17_+_27895609 0.313 ENST00000581411.2
ENST00000301057.7
TP53I13

tumor protein p53 inducible protein 13

chr9_-_115095123 0.312 ENST00000458258.1
PTBP3
polypyrimidine tract binding protein 3
chr12_+_79439405 0.307 ENST00000552744.1
SYT1
synaptotagmin I
chr9_+_138392483 0.304 ENST00000241600.5
MRPS2
mitochondrial ribosomal protein S2
chr12_+_3069037 0.304 ENST00000397122.2
TEAD4
TEA domain family member 4
chr22_+_18593446 0.304 ENST00000316027.6
TUBA8
tubulin, alpha 8
chr16_+_532503 0.297 ENST00000412256.1
RAB11FIP3
RAB11 family interacting protein 3 (class II)
chr7_-_72722783 0.297 ENST00000428206.1
ENST00000252594.6
ENST00000310326.8
ENST00000438747.2
NSUN5



NOP2/Sun domain family, member 5



chr17_-_76778339 0.295 ENST00000591455.1
ENST00000446868.3
ENST00000361101.4
ENST00000589296.1
CYTH1



cytohesin 1



chr19_+_41305085 0.293 ENST00000303961.4
EGLN2
egl-9 family hypoxia-inducible factor 2
chr17_-_79212825 0.288 ENST00000374769.2
ENTHD2
ENTH domain containing 2
chr10_-_33623826 0.288 ENST00000374867.2
NRP1
neuropilin 1
chr3_+_122283064 0.288 ENST00000296161.4
DTX3L
deltex 3-like (Drosophila)
chr19_+_18530184 0.287 ENST00000601357.2
SSBP4
single stranded DNA binding protein 4
chr3_+_184033551 0.280 ENST00000456033.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr12_-_76879852 0.279 ENST00000548341.1
OSBPL8
oxysterol binding protein-like 8
chr14_-_102771462 0.279 ENST00000522874.1
MOK
MOK protein kinase
chr14_-_23398565 0.278 ENST00000397440.4
ENST00000538452.1
ENST00000421938.2
ENST00000554867.1
ENST00000556616.1
ENST00000216350.8
ENST00000553550.1
ENST00000397441.2
ENST00000553897.1
PRMT5








protein arginine methyltransferase 5








chrX_-_135962876 0.276 ENST00000431446.3
ENST00000570135.1
ENST00000320676.7
ENST00000562646.1
RBMX



RNA binding motif protein, X-linked



chr8_-_135522425 0.272 ENST00000521673.1
ZFAT
zinc finger and AT hook domain containing
chr19_+_14017116 0.268 ENST00000589606.1
CC2D1A
coiled-coil and C2 domain containing 1A
chr10_-_33623564 0.264 ENST00000374875.1
ENST00000374822.4
NRP1

neuropilin 1

chr19_-_5903714 0.263 ENST00000252675.5
ENST00000308961.4
ENST00000592634.1
ENST00000418389.2
ENST00000586349.1
ENST00000585661.1
FUT5
NDUFA11


AC024592.12

fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa


Uncharacterized protein

chr16_+_28834303 0.262 ENST00000340394.8
ENST00000325215.6
ENST00000395547.2
ENST00000336783.4
ENST00000382686.4
ENST00000564304.1
ATXN2L





ataxin 2-like





chr12_+_53895364 0.259 ENST00000552817.1
ENST00000394357.2
TARBP2

TAR (HIV-1) RNA binding protein 2

chr22_+_50624323 0.258 ENST00000380909.4
ENST00000303434.4
TRABD

TraB domain containing

chr8_+_19536083 0.250 ENST00000519803.1
RP11-1105O14.1
RP11-1105O14.1
chr2_-_232329186 0.249 ENST00000322723.4
NCL
nucleolin
chr19_-_54693401 0.243 ENST00000338624.6
MBOAT7
membrane bound O-acyltransferase domain containing 7
chr10_+_47894572 0.241 ENST00000355876.5
FAM21B
family with sequence similarity 21, member B
chr19_+_56652643 0.239 ENST00000586123.1
ZNF444
zinc finger protein 444
chr3_-_71114066 0.239 ENST00000485326.2
FOXP1
forkhead box P1
chr7_+_65552756 0.237 ENST00000450043.1
AC068533.7
AC068533.7
chr16_+_69958887 0.235 ENST00000568684.1
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr17_-_40288449 0.233 ENST00000552162.1
ENST00000550504.1
RAB5C

RAB5C, member RAS oncogene family

chr16_-_67514982 0.230 ENST00000565835.1
ENST00000540149.1
ENST00000290949.3
ATP6V0D1


ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1


chr16_+_88636875 0.230 ENST00000569435.1
ZC3H18
zinc finger CCCH-type containing 18
chr5_-_180237082 0.229 ENST00000506889.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr9_+_139839711 0.224 ENST00000224181.3
C8G
complement component 8, gamma polypeptide
chr16_+_88636789 0.224 ENST00000301011.5
ENST00000452588.2
ZC3H18

zinc finger CCCH-type containing 18

chr2_+_233527443 0.221 ENST00000410095.1
EFHD1
EF-hand domain family, member D1
chr5_-_179227540 0.219 ENST00000520875.1
MGAT4B
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr19_+_36631867 0.219 ENST00000588780.1
CAPNS1
calpain, small subunit 1
chr8_+_23104130 0.219 ENST00000313219.7
ENST00000519984.1
CHMP7

charged multivesicular body protein 7

chr8_+_9046503 0.218 ENST00000512942.2
RP11-10A14.5
RP11-10A14.5
chr1_+_24069952 0.218 ENST00000609199.1
TCEB3
transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
chr7_+_29234101 0.217 ENST00000435288.2
CHN2
chimerin 2
chr1_-_205091115 0.216 ENST00000264515.6
ENST00000367164.1
RBBP5

retinoblastoma binding protein 5

chr1_-_115053781 0.215 ENST00000358465.2
ENST00000369543.2
TRIM33

tripartite motif containing 33

chr22_+_18593507 0.213 ENST00000330423.3
TUBA8
tubulin, alpha 8
chrX_-_48776292 0.212 ENST00000376509.4
PIM2
pim-2 oncogene
chr3_+_184032919 0.210 ENST00000427845.1
ENST00000342981.4
ENST00000319274.6
EIF4G1


eukaryotic translation initiation factor 4 gamma, 1


chr16_+_16043406 0.209 ENST00000399410.3
ENST00000399408.2
ENST00000346370.5
ENST00000351154.5
ENST00000345148.5
ENST00000349029.5
ABCC1





ATP-binding cassette, sub-family C (CFTR/MRP), member 1





chr19_+_18077881 0.207 ENST00000609922.1
KCNN1
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
chr1_+_198608146 0.205 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
PTPRC









protein tyrosine phosphatase, receptor type, C









chr16_+_14802801 0.204 ENST00000526520.1
ENST00000531598.2
NPIPA3

nuclear pore complex interacting protein family, member A3

chr2_-_230786679 0.201 ENST00000543084.1
ENST00000343290.5
ENST00000389044.4
ENST00000283943.5
TRIP12



thyroid hormone receptor interactor 12



chr6_+_30524663 0.201 ENST00000376560.3
PRR3
proline rich 3
chr7_+_129015484 0.201 ENST00000490911.1
AHCYL2
adenosylhomocysteinase-like 2
chr2_-_230786619 0.201 ENST00000389045.3
ENST00000409677.1
TRIP12

thyroid hormone receptor interactor 12

chr11_-_57177586 0.200 ENST00000529411.1
RP11-872D17.8
Uncharacterized protein
chr9_-_139838986 0.199 ENST00000443788.1
FBXW5
F-box and WD repeat domain containing 5
chr3_+_184033135 0.197 ENST00000424196.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr4_-_36245561 0.192 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr17_-_79212884 0.192 ENST00000300714.3
ENTHD2
ENTH domain containing 2
chr7_+_30951461 0.192 ENST00000311813.4
AQP1
aquaporin 1 (Colton blood group)
chr3_+_57541975 0.191 ENST00000487257.1
ENST00000311180.8
PDE12

phosphodiesterase 12

chr15_-_72563585 0.189 ENST00000287196.9
ENST00000260376.7
PARP6

poly (ADP-ribose) polymerase family, member 6

chr16_-_67281413 0.187 ENST00000258201.4
FHOD1
formin homology 2 domain containing 1
chr4_-_165898768 0.185 ENST00000329314.5
TRIM61
tripartite motif containing 61
chr17_+_2699697 0.184 ENST00000254695.8
ENST00000366401.4
ENST00000542807.1
RAP1GAP2


RAP1 GTPase activating protein 2


chr3_+_190105909 0.182 ENST00000456423.1
CLDN16
claudin 16
chr19_-_36822551 0.178 ENST00000591372.1
LINC00665
long intergenic non-protein coding RNA 665
chr6_+_30525051 0.178 ENST00000376557.3
PRR3
proline rich 3
chr7_+_29234028 0.178 ENST00000222792.6
CHN2
chimerin 2
chr19_+_54694119 0.175 ENST00000456872.1
ENST00000302937.4
ENST00000429671.2
TSEN34


TSEN34 tRNA splicing endonuclease subunit


chr8_+_9183618 0.173 ENST00000518619.1
RP11-115J16.1
RP11-115J16.1
chr16_+_30953696 0.173 ENST00000566320.2
ENST00000565939.1
FBXL19

F-box and leucine-rich repeat protein 19

chr3_+_151986709 0.172 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
MBNL1



muscleblind-like splicing regulator 1



chr1_-_3816779 0.170 ENST00000361605.3
C1orf174
chromosome 1 open reading frame 174
chr19_+_57831829 0.167 ENST00000321545.4
ZNF543
zinc finger protein 543
chr2_+_113342163 0.166 ENST00000409719.1
CHCHD5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr14_-_91884115 0.164 ENST00000389857.6
CCDC88C
coiled-coil domain containing 88C
chr15_+_98503922 0.160 ENST00000268042.6
ARRDC4
arrestin domain containing 4
chr5_-_39270725 0.159 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB


FYN binding protein


chr15_-_59225844 0.158 ENST00000380516.2
SLTM
SAFB-like, transcription modulator
chr22_+_35776354 0.156 ENST00000412893.1
HMOX1
heme oxygenase (decycling) 1
chr19_+_39936207 0.154 ENST00000594729.1
SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr1_+_17914907 0.153 ENST00000375420.3
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr10_-_22292613 0.151 ENST00000376980.3
DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr9_+_131644781 0.151 ENST00000259324.5
LRRC8A
leucine rich repeat containing 8 family, member A
chr3_+_14693247 0.151 ENST00000383794.3
ENST00000303688.7
CCDC174

coiled-coil domain containing 174

chr12_-_109221160 0.146 ENST00000326470.5
SSH1
slingshot protein phosphatase 1
chr12_-_25348007 0.146 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
CASC1






cancer susceptibility candidate 1






chr2_-_85625857 0.146 ENST00000453973.1
CAPG
capping protein (actin filament), gelsolin-like
chr6_-_32145101 0.145 ENST00000375104.2
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr2_-_25194476 0.144 ENST00000534855.1
DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr13_+_24844857 0.141 ENST00000409126.1
ENST00000343003.6
SPATA13

spermatogenesis associated 13

chr19_-_13261160 0.138 ENST00000343587.5
ENST00000591197.1
STX10

syntaxin 10

chr14_+_89290965 0.137 ENST00000345383.5
ENST00000536576.1
ENST00000346301.4
ENST00000338104.6
ENST00000354441.6
ENST00000380656.2
ENST00000556651.1
ENST00000554686.1
TTC8







tetratricopeptide repeat domain 8







chr15_-_81282133 0.136 ENST00000261758.4
MESDC2
mesoderm development candidate 2
chr7_+_94536514 0.135 ENST00000413325.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr3_+_111578131 0.133 ENST00000498699.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr19_+_7599597 0.133 ENST00000414982.3
ENST00000450331.3
PNPLA6

patatin-like phospholipase domain containing 6

chr17_-_43487780 0.133 ENST00000532038.1
ENST00000528677.1
ARHGAP27

Rho GTPase activating protein 27

chr19_+_39936186 0.131 ENST00000432763.2
ENST00000402194.2
ENST00000601515.1
SUPT5H


suppressor of Ty 5 homolog (S. cerevisiae)


chr19_+_56652686 0.130 ENST00000592949.1
ZNF444
zinc finger protein 444
chr7_+_100728720 0.129 ENST00000306085.6
ENST00000412507.1
TRIM56

tripartite motif containing 56

chr5_-_55008072 0.126 ENST00000512208.1
SLC38A9
solute carrier family 38, member 9
chr19_+_49122785 0.125 ENST00000598088.1
SPHK2
sphingosine kinase 2
chr17_-_64225508 0.124 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr18_+_9102669 0.123 ENST00000497577.2
NDUFV2
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
chr19_+_39936267 0.121 ENST00000359191.6
SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr10_-_43892279 0.120 ENST00000443950.2
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr16_-_28506840 0.119 ENST00000569430.1
CLN3
ceroid-lipofuscinosis, neuronal 3
chr7_+_149416439 0.119 ENST00000497895.1
KRBA1
KRAB-A domain containing 1
chr16_+_2479390 0.119 ENST00000397066.4
CCNF
cyclin F
chr9_-_139839064 0.115 ENST00000325285.3
ENST00000428398.1
FBXW5

F-box and WD repeat domain containing 5

chr19_+_49122548 0.113 ENST00000245222.4
ENST00000340932.3
ENST00000601712.1
ENST00000600537.1
SPHK2



sphingosine kinase 2



chr8_+_98900132 0.111 ENST00000520016.1
MATN2
matrilin 2
chr12_+_27091387 0.111 ENST00000544111.1
FGFR1OP2
FGFR1 oncogene partner 2
chr17_+_78388959 0.109 ENST00000518137.1
ENST00000520367.1
ENST00000523999.1
ENST00000323854.5
ENST00000522751.1
ENDOV




endonuclease V




chr10_-_106240032 0.109 ENST00000447860.1
RP11-127O4.3
RP11-127O4.3
chr12_-_71512027 0.107 ENST00000549357.1
CTD-2021H9.3
Uncharacterized protein
chr16_+_640201 0.107 ENST00000563109.1
RAB40C
RAB40C, member RAS oncogene family
chr22_+_29664241 0.106 ENST00000436425.1
ENST00000447973.1
EWSR1

EWS RNA-binding protein 1

chr1_+_2487402 0.106 ENST00000451778.1
TNFRSF14
tumor necrosis factor receptor superfamily, member 14
chr10_-_43892668 0.105 ENST00000544000.1
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr11_-_107729504 0.104 ENST00000265836.7
SLC35F2
solute carrier family 35, member F2
chr17_+_53828333 0.100 ENST00000268896.5
PCTP
phosphatidylcholine transfer protein
chr9_+_139839686 0.100 ENST00000371634.2
C8G
complement component 8, gamma polypeptide
chr15_-_59225758 0.099 ENST00000558486.1
ENST00000560682.1
ENST00000249736.7
ENST00000559880.1
ENST00000536328.1
SLTM




SAFB-like, transcription modulator




chr5_+_158654712 0.099 ENST00000520323.1
CTB-11I22.2
CTB-11I22.2
chr1_-_24741525 0.099 ENST00000374409.1
STPG1
sperm-tail PG-rich repeat containing 1
chr17_+_53828381 0.098 ENST00000576183.1
PCTP
phosphatidylcholine transfer protein
chr11_-_73882057 0.098 ENST00000334126.7
ENST00000313663.7
C2CD3

C2 calcium-dependent domain containing 3


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.3 1.2 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.2 1.7 GO:0007296 vitellogenesis(GO:0007296)
0.2 0.7 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.2 1.1 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.1 0.4 GO:0100012 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) Wnt signaling pathway involved in somitogenesis(GO:0090244) regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
0.1 0.4 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 2.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.6 GO:0035063 nuclear speck organization(GO:0035063)
0.1 4.0 GO:0045730 respiratory burst(GO:0045730)
0.1 0.6 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1 0.6 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.1 0.7 GO:0070417 cellular response to cold(GO:0070417)
0.1 1.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.5 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.8 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 0.9 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 1.0 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.2 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.1 0.4 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.2 GO:0071288 carbon dioxide transmembrane transport(GO:0035378) cellular response to mercury ion(GO:0071288)
0.1 0.4 GO:0060480 lung goblet cell differentiation(GO:0060480) lobar bronchus epithelium development(GO:0060481) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 0.4 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 0.2 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.1 0.2 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.1 0.7 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.2 GO:0001300 chronological cell aging(GO:0001300)
0.0 0.1 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.7 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.2 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.3 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.5 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.9 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.4 GO:1902915 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.2 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.3 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195) peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.2 GO:0034395 heme oxidation(GO:0006788) negative regulation of mast cell cytokine production(GO:0032764) regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0 0.5 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.2 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.3 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.1 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.0 0.9 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.0 0.1 GO:0045062 extrathymic T cell selection(GO:0045062)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.3 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0 0.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.3 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.4 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785)
0.0 0.1 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.1 GO:0050893 sensory processing(GO:0050893)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.2 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.2 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.1 GO:0061511 centriole elongation(GO:0061511)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.2 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.0 0.2 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.5 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 0.8 GO:0035329 hippo signaling(GO:0035329)
0.0 0.2 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.6 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.0 GO:0032010 phagolysosome(GO:0032010)
0.3 1.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.5 GO:0031213 RSF complex(GO:0031213)
0.1 0.4 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.8 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.6 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.4 GO:0032044 DSIF complex(GO:0032044)
0.1 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.6 GO:0097443 sorting endosome(GO:0097443)
0.1 0.2 GO:0072563 endothelial microparticle(GO:0072563)
0.0 0.4 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.3 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.4 GO:0000322 storage vacuole(GO:0000322)
0.0 0.2 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655) extracellular membrane-bounded organelle(GO:0065010)
0.0 0.1 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.6 GO:0097440 apical dendrite(GO:0097440)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:0034709 methylosome(GO:0034709)
0.0 0.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 1.6 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.7 GO:0097546 ciliary base(GO:0097546)
0.0 0.8 GO:0045095 keratin filament(GO:0045095)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0002113 interleukin-33 binding(GO:0002113)
0.3 1.6 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.2 4.0 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 0.9 GO:0045569 TRAIL binding(GO:0045569)
0.1 0.5 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.4 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.4 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 0.2 GO:0015235 cobalamin transporter activity(GO:0015235)
0.1 0.2 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.1 2.2 GO:0001848 complement binding(GO:0001848)
0.1 0.5 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.5 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.3 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1 0.3 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.1 0.6 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.7 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.4 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.8 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.2 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.9 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.3 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.3 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.3 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.4 GO:0039706 co-receptor binding(GO:0039706) receptor antagonist activity(GO:0048019)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0005534 galactose binding(GO:0005534)
0.0 0.8 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 1.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.0 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.2 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.1 ST_GAQ_PATHWAY G alpha q Pathway
0.0 4.9 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.6 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 1.4 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.9 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 0.4 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.7 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.4 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.6 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.3 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT Genes involved in Initial triggering of complement
0.1 4.2 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 2.2 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.7 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.9 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.6 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.9 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.3 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.8 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.4 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.8 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.4 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.8 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.6 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.3 REACTOME_COMPLEMENT_CASCADE Genes involved in Complement cascade
0.0 0.2 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.0 0.2 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains