Motif ID: VAX1_GSX2

Z-value: 0.689

Transcription factors associated with VAX1_GSX2:

Gene SymbolEntrez IDGene Name
GSX2 ENSG00000180613.6 GSX2
VAX1 ENSG00000148704.8 VAX1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
VAX1hg19_v2_chr10_-_118897806_1188978170.561.2e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of VAX1_GSX2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_92777606 2.184 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L






sterile alpha motif domain containing 9-like






chr4_-_169239921 2.140 ENST00000514995.1
ENST00000393743.3
DDX60

DEAD (Asp-Glu-Ala-Asp) box polypeptide 60

chr5_-_150473127 1.444 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr2_+_102953608 1.153 ENST00000311734.2
ENST00000409584.1
IL1RL1

interleukin 1 receptor-like 1

chr1_+_192778161 0.979 ENST00000235382.5
RGS2
regulator of G-protein signaling 2, 24kDa
chr7_+_100770328 0.916 ENST00000223095.4
ENST00000445463.2
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr2_-_101925055 0.902 ENST00000295317.3
RNF149
ring finger protein 149
chr4_-_25865159 0.687 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3



sel-1 suppressor of lin-12-like 3 (C. elegans)



chr13_-_41593425 0.624 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr19_+_48949087 0.598 ENST00000598711.1
GRWD1
glutamate-rich WD repeat containing 1
chr12_+_78359999 0.508 ENST00000550503.1
NAV3
neuron navigator 3
chr21_-_35899113 0.488 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
RCAN1


regulator of calcineurin 1


chr3_+_149191723 0.456 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr9_+_125132803 0.450 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr9_+_125133315 0.441 ENST00000223423.4
ENST00000362012.2
PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr11_-_795400 0.416 ENST00000526152.1
ENST00000456706.2
ENST00000528936.1
SLC25A22


solute carrier family 25 (mitochondrial carrier: glutamate), member 22


chr5_+_36606700 0.405 ENST00000416645.2
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr19_+_48949030 0.379 ENST00000253237.5
GRWD1
glutamate-rich WD repeat containing 1
chr14_+_61654271 0.364 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH


protein kinase C, eta


chr11_-_795286 0.364 ENST00000533385.1
ENST00000527723.1
SLC25A22

solute carrier family 25 (mitochondrial carrier: glutamate), member 22

chr11_-_795170 0.350 ENST00000481290.1
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr10_-_92681033 0.338 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr16_+_29832634 0.300 ENST00000565164.1
ENST00000570234.1
MVP

major vault protein

chr12_-_112123524 0.293 ENST00000327551.6
BRAP
BRCA1 associated protein
chr15_+_89631647 0.291 ENST00000569550.1
ENST00000565066.1
ENST00000565973.1
ABHD2


abhydrolase domain containing 2


chr9_-_16728161 0.285 ENST00000603713.1
ENST00000603313.1
BNC2

basonuclin 2

chr9_+_125133467 0.282 ENST00000426608.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr18_+_3447572 0.282 ENST00000548489.2
TGIF1
TGFB-induced factor homeobox 1
chr4_-_119759795 0.274 ENST00000419654.2
SEC24D
SEC24 family member D
chr14_+_67831576 0.269 ENST00000555876.1
EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr20_-_50722183 0.269 ENST00000371523.4
ZFP64
ZFP64 zinc finger protein
chr2_-_220264703 0.257 ENST00000519905.1
ENST00000523282.1
ENST00000434339.1
ENST00000457935.1
DNPEP



aspartyl aminopeptidase



chrX_-_18690210 0.254 ENST00000379984.3
RS1
retinoschisin 1
chr2_+_228736335 0.251 ENST00000440997.1
ENST00000545118.1
DAW1

dynein assembly factor with WDR repeat domains 1

chr5_+_66300446 0.249 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr7_+_55433131 0.244 ENST00000254770.2
LANCL2
LanC lantibiotic synthetase component C-like 2 (bacterial)
chr2_-_99871570 0.243 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
LYG2


lysozyme G-like 2


chr1_+_160370344 0.243 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr15_-_75748143 0.205 ENST00000568431.1
ENST00000568309.1
ENST00000568190.1
ENST00000570115.1
ENST00000564778.1
SIN3A




SIN3 transcription regulator family member A




chr4_-_103749205 0.203 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr17_+_72427477 0.202 ENST00000342648.5
ENST00000481232.1
GPRC5C

G protein-coupled receptor, family C, group 5, member C

chr1_-_109618566 0.198 ENST00000338366.5
TAF13
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
chr16_+_53133070 0.190 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr20_+_43990576 0.189 ENST00000372727.1
ENST00000414310.1
SYS1

SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)

chr15_+_63188009 0.187 ENST00000557900.1
RP11-1069G10.2
RP11-1069G10.2
chr2_-_166060382 0.183 ENST00000409101.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr10_-_28571015 0.182 ENST00000375719.3
ENST00000375732.1
MPP7

membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)

chr5_+_66300464 0.181 ENST00000436277.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr1_+_158978768 0.175 ENST00000447473.2
IFI16
interferon, gamma-inducible protein 16
chr1_+_117544366 0.169 ENST00000256652.4
ENST00000369470.1
CD101

CD101 molecule

chr7_+_37723420 0.169 ENST00000476620.1
EPDR1
ependymin related 1
chr6_+_34204642 0.169 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1




high mobility group AT-hook 1




chr7_-_99716940 0.168 ENST00000440225.1
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr8_+_54764346 0.162 ENST00000297313.3
ENST00000344277.6
RGS20

regulator of G-protein signaling 20

chr15_-_42264702 0.160 ENST00000220325.4
EHD4
EH-domain containing 4
chr4_+_110736659 0.157 ENST00000394631.3
ENST00000226796.6
GAR1

GAR1 ribonucleoprotein

chr17_+_43238438 0.154 ENST00000593138.1
ENST00000586681.1
HEXIM2

hexamethylene bis-acetamide inducible 2

chr4_+_66536248 0.154 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1

RP11-807H7.1

chr5_+_142286887 0.154 ENST00000451259.1
ARHGAP26
Rho GTPase activating protein 26
chr1_-_150669604 0.153 ENST00000427665.1
ENST00000540514.1
GOLPH3L

golgi phosphoprotein 3-like

chr16_+_69345243 0.152 ENST00000254950.11
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr15_+_62853562 0.149 ENST00000561311.1
TLN2
talin 2
chr5_-_139726181 0.144 ENST00000507104.1
ENST00000230990.6
HBEGF

heparin-binding EGF-like growth factor

chr2_-_3521518 0.142 ENST00000382093.5
ADI1
acireductone dioxygenase 1
chr12_-_15815626 0.141 ENST00000540613.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr6_-_160209471 0.139 ENST00000539948.1
TCP1
t-complex 1
chr15_+_89631381 0.139 ENST00000352732.5
ABHD2
abhydrolase domain containing 2
chr1_-_9953295 0.137 ENST00000377258.1
CTNNBIP1
catenin, beta interacting protein 1
chr6_-_82957433 0.137 ENST00000306270.7
IBTK
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr1_+_162336686 0.137 ENST00000420220.1
C1orf226
chromosome 1 open reading frame 226
chr7_-_33102399 0.136 ENST00000242210.7
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr19_-_58951496 0.134 ENST00000254166.3
ZNF132
zinc finger protein 132
chr7_-_33102338 0.133 ENST00000610140.1
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr3_+_111393501 0.133 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr3_+_111630451 0.131 ENST00000495180.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr1_-_207226313 0.131 ENST00000367084.1
YOD1
YOD1 deubiquitinase
chr4_-_66536057 0.130 ENST00000273854.3
EPHA5
EPH receptor A5
chr17_-_73901494 0.129 ENST00000309352.3
MRPL38
mitochondrial ribosomal protein L38
chr19_+_36632204 0.129 ENST00000592354.1
CAPNS1
calpain, small subunit 1
chr19_+_36632485 0.124 ENST00000586963.1
CAPNS1
calpain, small subunit 1
chr5_+_154092396 0.124 ENST00000336314.4
LARP1
La ribonucleoprotein domain family, member 1
chr4_-_103749179 0.124 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr5_+_36608280 0.124 ENST00000513646.1
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr1_-_151965048 0.122 ENST00000368809.1
S100A10
S100 calcium binding protein A10
chr16_-_31085514 0.122 ENST00000300849.4
ZNF668
zinc finger protein 668
chr2_+_220363579 0.120 ENST00000313597.5
ENST00000373917.3
ENST00000358215.3
ENST00000373908.1
ENST00000455657.1
ENST00000435316.1
ENST00000341142.3
GMPPA






GDP-mannose pyrophosphorylase A






chr8_-_112248400 0.119 ENST00000519506.1
ENST00000522778.1
RP11-946L20.4

RP11-946L20.4

chr6_+_26402465 0.118 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1





butyrophilin, subfamily 3, member A1





chr3_+_101504200 0.118 ENST00000422132.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chrX_-_109590174 0.117 ENST00000372054.1
GNG5P2
guanine nucleotide binding protein (G protein), gamma 5 pseudogene 2
chr10_+_47894023 0.117 ENST00000358474.5
FAM21B
family with sequence similarity 21, member B
chr15_+_75491213 0.116 ENST00000360639.2
C15orf39
chromosome 15 open reading frame 39
chr7_-_111424462 0.114 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chr4_-_66536196 0.113 ENST00000511294.1
EPHA5
EPH receptor A5
chr6_+_26402517 0.111 ENST00000414912.2
BTN3A1
butyrophilin, subfamily 3, member A1
chr17_-_73663245 0.106 ENST00000584999.1
ENST00000317905.5
ENST00000420326.2
ENST00000340830.5
RECQL5



RecQ protein-like 5



chr19_+_11071546 0.102 ENST00000358026.2
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr12_-_127544894 0.098 ENST00000546062.1
ENST00000512624.2
ENST00000540244.1
RP11-575F12.1


RP11-575F12.1


chr2_-_133429091 0.096 ENST00000345008.6
LYPD1
LY6/PLAUR domain containing 1
chr17_-_29645836 0.095 ENST00000578584.1
CTD-2370N5.3
CTD-2370N5.3
chr4_-_36245561 0.094 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr8_+_92261516 0.092 ENST00000276609.3
ENST00000309536.2
SLC26A7

solute carrier family 26 (anion exchanger), member 7

chr11_+_29181503 0.092 ENST00000530960.1
RP11-466I1.1
RP11-466I1.1
chrX_+_37639264 0.092 ENST00000378588.4
CYBB
cytochrome b-245, beta polypeptide
chr7_-_99716952 0.089 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6










TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa










chr7_-_111424506 0.087 ENST00000450156.1
ENST00000494651.2
DOCK4

dedicator of cytokinesis 4

chr11_-_26593649 0.083 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr1_+_186369704 0.083 ENST00000574641.1
OCLM
oculomedin
chr1_+_154401791 0.082 ENST00000476006.1
IL6R
interleukin 6 receptor
chr1_+_84630574 0.082 ENST00000413538.1
ENST00000417530.1
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr15_+_90118723 0.081 ENST00000560985.1
TICRR
TOPBP1-interacting checkpoint and replication regulator
chr15_+_64680003 0.081 ENST00000261884.3
TRIP4
thyroid hormone receptor interactor 4
chr11_-_133826852 0.078 ENST00000533871.2
ENST00000321016.8
IGSF9B

immunoglobulin superfamily, member 9B

chr16_-_66764119 0.078 ENST00000569320.1
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr6_-_138833630 0.077 ENST00000533765.1
NHSL1
NHS-like 1
chr17_+_67590125 0.077 ENST00000591334.1
AC003051.1
AC003051.1
chr2_+_187371440 0.077 ENST00000445547.1
ZC3H15
zinc finger CCCH-type containing 15
chr5_+_148443049 0.076 ENST00000515304.1
ENST00000507318.1
CTC-529P8.1

CTC-529P8.1

chr15_+_90118685 0.075 ENST00000268138.7
TICRR
TOPBP1-interacting checkpoint and replication regulator
chr12_+_113587558 0.073 ENST00000335621.6
CCDC42B
coiled-coil domain containing 42B
chr5_-_98262240 0.073 ENST00000284049.3
CHD1
chromodomain helicase DNA binding protein 1
chr5_-_20575959 0.071 ENST00000507958.1
CDH18
cadherin 18, type 2
chr15_-_75748115 0.070 ENST00000360439.4
SIN3A
SIN3 transcription regulator family member A
chr12_+_106751436 0.068 ENST00000228347.4
POLR3B
polymerase (RNA) III (DNA directed) polypeptide B
chr19_-_19302931 0.068 ENST00000444486.3
ENST00000514819.3
ENST00000162023.5
ENST00000585679.1
MEF2BNB-MEF2B

MEF2B
MEF2BNB
MEF2BNB-MEF2B readthrough

myocyte enhancer factor 2B
MEF2B neighbor
chr5_-_147286065 0.068 ENST00000318315.4
ENST00000515291.1
C5orf46

chromosome 5 open reading frame 46

chr12_-_22063787 0.064 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr4_+_95128748 0.064 ENST00000359052.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr2_+_198380289 0.064 ENST00000233892.4
ENST00000409916.1
MOB4

MOB family member 4, phocein

chr18_-_54305658 0.061 ENST00000586262.1
ENST00000217515.6
TXNL1

thioredoxin-like 1

chrX_+_107334983 0.061 ENST00000457035.1
ENST00000545696.1
ATG4A

autophagy related 4A, cysteine peptidase

chrX_+_21958674 0.060 ENST00000404933.2
SMS
spermine synthase
chr17_+_28443799 0.060 ENST00000584423.1
ENST00000247026.5
NSRP1

nuclear speckle splicing regulatory protein 1

chr2_+_32288725 0.059 ENST00000315285.3
SPAST
spastin
chr11_-_27722021 0.059 ENST00000356660.4
ENST00000418212.1
ENST00000533246.1
BDNF


brain-derived neurotrophic factor


chr10_-_27529486 0.058 ENST00000375888.1
ACBD5
acyl-CoA binding domain containing 5
chr14_-_104181771 0.058 ENST00000554913.1
ENST00000554974.1
ENST00000553361.1
ENST00000555055.1
ENST00000555964.1
ENST00000556682.1
ENST00000445556.1
ENST00000553332.1
ENST00000352127.7
XRCC3








X-ray repair complementing defective repair in Chinese hamster cells 3








chr19_+_19303008 0.058 ENST00000353145.1
ENST00000421262.3
ENST00000303088.4
ENST00000456252.3
ENST00000593273.1
RFXANK




regulatory factor X-associated ankyrin-containing protein




chr19_+_50180317 0.057 ENST00000534465.1
PRMT1
protein arginine methyltransferase 1
chr7_-_14028488 0.057 ENST00000405358.4
ETV1
ets variant 1
chr18_+_46065393 0.057 ENST00000256413.3
CTIF
CBP80/20-dependent translation initiation factor
chr1_-_150669500 0.056 ENST00000271732.3
GOLPH3L
golgi phosphoprotein 3-like
chr16_+_14280742 0.056 ENST00000341243.5
MKL2
MKL/myocardin-like 2
chr21_-_43346790 0.056 ENST00000329623.7
C2CD2
C2 calcium-dependent domain containing 2
chr13_-_36050819 0.055 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr17_-_64225508 0.054 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr3_-_191000172 0.054 ENST00000427544.2
UTS2B
urotensin 2B
chr8_-_97273807 0.053 ENST00000517720.1
ENST00000287025.3
ENST00000523821.1
MTERFD1


MTERF domain containing 1


chr1_-_36789755 0.053 ENST00000270824.1
EVA1B
eva-1 homolog B (C. elegans)
chr17_+_12569472 0.052 ENST00000343344.4
MYOCD
myocardin
chr10_+_24755416 0.051 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217


KIAA1217


chr15_+_75491203 0.051 ENST00000562637.1
C15orf39
chromosome 15 open reading frame 39
chr7_-_121944491 0.050 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1


FEZ family zinc finger 1


chr4_+_159727272 0.050 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr7_-_14029283 0.049 ENST00000433547.1
ENST00000405192.2
ETV1

ets variant 1

chr1_-_68698197 0.049 ENST00000370973.2
ENST00000370971.1
WLS

wntless Wnt ligand secretion mediator

chr7_+_93535866 0.048 ENST00000429473.1
ENST00000430875.1
ENST00000428834.1
GNGT1


guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1


chr11_-_71823266 0.048 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
ANAPC15


anaphase promoting complex subunit 15


chr1_-_68698222 0.044 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS



wntless Wnt ligand secretion mediator



chr11_-_36619771 0.044 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
RAG2


recombination activating gene 2


chr1_+_84630645 0.043 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr11_-_65149422 0.043 ENST00000526432.1
ENST00000527174.1
SLC25A45

solute carrier family 25, member 45

chr7_+_44646162 0.043 ENST00000439616.2
OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr12_-_6233828 0.043 ENST00000572068.1
ENST00000261405.5
VWF

von Willebrand factor

chr12_+_7014064 0.042 ENST00000443597.2
LRRC23
leucine rich repeat containing 23
chr12_+_101988627 0.040 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1








myosin binding protein C, slow type








chr1_-_92952433 0.040 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr6_+_78400375 0.040 ENST00000602452.2
MEI4
meiosis-specific 4 homolog (S. cerevisiae)
chr21_+_17792672 0.040 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr11_+_92085262 0.040 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT3


FAT atypical cadherin 3


chr15_+_41913690 0.039 ENST00000563576.1
MGA
MGA, MAX dimerization protein
chr1_-_21620877 0.038 ENST00000527991.1
ECE1
endothelin converting enzyme 1
chr7_+_99202003 0.036 ENST00000609449.1
GS1-259H13.2
GS1-259H13.2
chr7_+_100860949 0.036 ENST00000305105.2
ZNHIT1
zinc finger, HIT-type containing 1
chr19_+_50180409 0.036 ENST00000391851.4
PRMT1
protein arginine methyltransferase 1
chr19_+_21324827 0.036 ENST00000600692.1
ENST00000599296.1
ENST00000594425.1
ENST00000311048.7
ZNF431



zinc finger protein 431



chr19_+_50180507 0.036 ENST00000454376.2
ENST00000524771.1
PRMT1

protein arginine methyltransferase 1

chr6_+_110501621 0.035 ENST00000368930.1
ENST00000307731.1
CDC40

cell division cycle 40

chr15_+_36871983 0.035 ENST00000437989.2
ENST00000569302.1
C15orf41

chromosome 15 open reading frame 41

chr18_-_68004529 0.034 ENST00000578633.1
RP11-484N16.1
RP11-484N16.1
chr17_-_18430160 0.034 ENST00000392176.3
FAM106A
family with sequence similarity 106, member A
chr7_-_81399355 0.033 ENST00000457544.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr6_+_155538093 0.033 ENST00000462408.2
TIAM2
T-cell lymphoma invasion and metastasis 2
chr1_+_207226574 0.033 ENST00000367080.3
ENST00000367079.2
PFKFB2

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

chr22_-_36903069 0.032 ENST00000216187.6
ENST00000423980.1
FOXRED2

FAD-dependent oxidoreductase domain containing 2

chr5_-_9630463 0.032 ENST00000382492.2
TAS2R1
taste receptor, type 2, member 1
chr16_+_31885079 0.032 ENST00000300870.10
ENST00000394846.3
ZNF267

zinc finger protein 267

chr7_-_99717463 0.032 ENST00000437822.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr1_+_236958554 0.032 ENST00000366577.5
ENST00000418145.2
MTR

5-methyltetrahydrofolate-homocysteine methyltransferase

chr6_+_46761118 0.031 ENST00000230588.4
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr2_+_32288657 0.030 ENST00000345662.1
SPAST
spastin
chr2_-_50201327 0.029 ENST00000412315.1
NRXN1
neurexin 1
chr1_+_81771806 0.029 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2





latrophilin 2





chr10_+_99205959 0.029 ENST00000352634.4
ENST00000353979.3
ENST00000370842.2
ENST00000345745.5
ZDHHC16



zinc finger, DHHC-type containing 16



chr12_+_16500037 0.028 ENST00000536371.1
ENST00000010404.2
MGST1

microsomal glutathione S-transferase 1

chr17_+_18086392 0.028 ENST00000541285.1
ALKBH5
alkB, alkylation repair homolog 5 (E. coli)
chr4_+_78432907 0.028 ENST00000286758.4
CXCL13
chemokine (C-X-C motif) ligand 13
chr11_+_46958248 0.027 ENST00000536126.1
ENST00000278460.7
ENST00000378618.2
ENST00000395460.2
ENST00000378615.3
ENST00000543718.1
C11orf49





chromosome 11 open reading frame 49





chr10_-_128110441 0.027 ENST00000456514.1
LINC00601
long intergenic non-protein coding RNA 601
chr7_-_81399411 0.027 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.3 0.9 GO:0001300 chronological cell aging(GO:0001300)
0.3 1.4 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.2 1.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.2 2.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 1.0 GO:0071877 regulation of adrenergic receptor signaling pathway(GO:0071877)
0.1 0.2 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.1 0.2 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 0.3 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 0.3 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 0.2 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 1.7 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.3 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 1.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.2 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.2 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 0.1 GO:0044053 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.0 0.4 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 1.1 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.1 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.0 0.1 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653) positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.6 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.3 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.0 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.4 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.2 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.0 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0097451 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451)
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.0 0.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0002113 interleukin-33 binding(GO:0002113)
0.2 1.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.2 0.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 1.1 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 0.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.3 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.4 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 1.0 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 1.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 0.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 1.6 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0016768 spermine synthase activity(GO:0016768)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 2.2 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.0 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID_HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.2 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.2 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds