Motif ID: UGGCACU

Z-value: 0.712





Activity profile for motif UGGCACU.

activity profile for motif UGGCACU


Sorted Z-values histogram for motif UGGCACU

Sorted Z-values for motif UGGCACU



Network of associatons between targets according to the STRING database.



First level regulatory network of UGGCACU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_15374033 0.939 ENST00000253688.5
ENST00000383791.3
SH3BP5

SH3-domain binding protein 5 (BTK-associated)

chr4_+_78078304 0.849 ENST00000316355.5
ENST00000354403.5
ENST00000502280.1
CCNG2


cyclin G2


chr11_-_94964354 0.728 ENST00000536441.1
SESN3
sestrin 3
chr10_+_112631547 0.719 ENST00000280154.7
ENST00000393104.2
PDCD4

programmed cell death 4 (neoplastic transformation inhibitor)

chrX_+_16964794 0.694 ENST00000357277.3
REPS2
RALBP1 associated Eps domain containing 2
chr9_+_101867359 0.632 ENST00000374994.4
TGFBR1
transforming growth factor, beta receptor 1
chr10_+_120789223 0.526 ENST00000425699.1
NANOS1
nanos homolog 1 (Drosophila)
chr13_+_98794810 0.516 ENST00000595437.1
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr6_-_34360413 0.502 ENST00000607016.1
NUDT3
nudix (nucleoside diphosphate linked moiety X)-type motif 3
chr6_+_64281906 0.481 ENST00000370651.3
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr1_-_20812690 0.459 ENST00000375078.3
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr5_+_76506706 0.436 ENST00000340978.3
ENST00000346042.3
ENST00000264917.5
ENST00000342343.4
ENST00000333194.4
PDE8B




phosphodiesterase 8B




chrX_-_13956737 0.402 ENST00000454189.2
GPM6B
glycoprotein M6B
chr16_-_68482440 0.394 ENST00000219334.5
SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr2_+_32502952 0.371 ENST00000238831.4
YIPF4
Yip1 domain family, member 4
chr16_-_80838195 0.362 ENST00000570137.2
CDYL2
chromodomain protein, Y-like 2
chr9_-_4741255 0.356 ENST00000381809.3
AK3
adenylate kinase 3
chr19_+_19174795 0.338 ENST00000318596.7
SLC25A42
solute carrier family 25, member 42
chrX_-_106959631 0.336 ENST00000486554.1
ENST00000372390.4
TSC22D3

TSC22 domain family, member 3

chr12_-_54673871 0.335 ENST00000209875.4
CBX5
chromobox homolog 5
chr2_+_159313452 0.335 ENST00000389757.3
ENST00000389759.3
PKP4

plakophilin 4

chr22_-_22221900 0.333 ENST00000215832.6
ENST00000398822.3
MAPK1

mitogen-activated protein kinase 1

chr1_-_68299130 0.328 ENST00000370982.3
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr6_-_16761678 0.325 ENST00000244769.4
ENST00000436367.1
ATXN1

ataxin 1

chr20_+_51588873 0.313 ENST00000371497.5
TSHZ2
teashirt zinc finger homeobox 2
chr3_+_38495333 0.312 ENST00000352511.4
ACVR2B
activin A receptor, type IIB
chr20_-_43438912 0.302 ENST00000541604.2
ENST00000372851.3
RIMS4

regulating synaptic membrane exocytosis 4

chr8_+_42752053 0.298 ENST00000307602.4
HOOK3
hook microtubule-tethering protein 3
chr5_-_171881491 0.291 ENST00000311601.5
SH3PXD2B
SH3 and PX domains 2B
chr9_+_32384617 0.286 ENST00000379923.1
ENST00000309951.6
ENST00000541043.1
ACO1


aconitase 1, soluble


chr6_+_14117872 0.272 ENST00000379153.3
CD83
CD83 molecule
chr10_+_92980517 0.269 ENST00000336126.5
PCGF5
polycomb group ring finger 5
chr3_+_169940153 0.268 ENST00000295797.4
PRKCI
protein kinase C, iota
chr16_+_81348528 0.261 ENST00000568107.2
GAN
gigaxonin
chr3_+_160473996 0.258 ENST00000498165.1
PPM1L
protein phosphatase, Mg2+/Mn2+ dependent, 1L
chr10_-_32345305 0.253 ENST00000302418.4
KIF5B
kinesin family member 5B
chr2_+_205410516 0.237 ENST00000406610.2
ENST00000462231.1
PARD3B

par-3 family cell polarity regulator beta

chr4_+_166794383 0.232 ENST00000061240.2
ENST00000507499.1
TLL1

tolloid-like 1

chr8_-_130951940 0.230 ENST00000522250.1
ENST00000522941.1
ENST00000522746.1
ENST00000520204.1
ENST00000519070.1
ENST00000520254.1
ENST00000519824.2
ENST00000519540.1
FAM49B







family with sequence similarity 49, member B







chr2_+_192542850 0.225 ENST00000410026.2
NABP1
nucleic acid binding protein 1
chr14_-_74551172 0.219 ENST00000553458.1
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr8_+_120885949 0.215 ENST00000523492.1
ENST00000286234.5
DEPTOR

DEP domain containing MTOR-interacting protein

chr11_-_82782861 0.210 ENST00000524635.1
ENST00000526205.1
ENST00000527633.1
ENST00000533486.1
ENST00000533276.2
RAB30




RAB30, member RAS oncogene family




chr1_-_109940550 0.207 ENST00000256637.6
SORT1
sortilin 1
chr11_+_117049445 0.206 ENST00000324225.4
ENST00000532960.1
SIDT2

SID1 transmembrane family, member 2

chr12_+_110906169 0.205 ENST00000377673.5
FAM216A
family with sequence similarity 216, member A
chrX_+_70316005 0.200 ENST00000374259.3
FOXO4
forkhead box O4
chr1_+_112162381 0.197 ENST00000433097.1
ENST00000369709.3
ENST00000436150.2
RAP1A


RAP1A, member of RAS oncogene family


chr3_+_138066539 0.197 ENST00000289104.4
MRAS
muscle RAS oncogene homolog
chr9_+_100263912 0.194 ENST00000259365.4
TMOD1
tropomodulin 1
chr5_+_102201430 0.189 ENST00000438793.3
ENST00000346918.2
PAM

peptidylglycine alpha-amidating monooxygenase

chr12_+_124457746 0.188 ENST00000540762.2
ENST00000392404.3
ENST00000538932.2
ENST00000337815.4
FAM101A
ZNF664


family with sequence similarity 101, member A
zinc finger protein 664


chr4_+_108745711 0.184 ENST00000394684.4
SGMS2
sphingomyelin synthase 2
chr10_+_114709999 0.182 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
TCF7L2






transcription factor 7-like 2 (T-cell specific, HMG-box)






chr9_-_3525968 0.182 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
RFX3


regulatory factor X, 3 (influences HLA class II expression)


chr2_+_173600671 0.178 ENST00000409036.1
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr8_+_38614807 0.178 ENST00000330691.6
ENST00000348567.4
TACC1

transforming, acidic coiled-coil containing protein 1

chr1_+_118148556 0.176 ENST00000369448.3
FAM46C
family with sequence similarity 46, member C
chrX_+_70752917 0.172 ENST00000373719.3
OGT
O-linked N-acetylglucosamine (GlcNAc) transferase
chr6_+_52226897 0.171 ENST00000442253.2
PAQR8
progestin and adipoQ receptor family member VIII
chr13_-_41706864 0.170 ENST00000379485.1
ENST00000499385.2
KBTBD6

kelch repeat and BTB (POZ) domain containing 6

chr10_+_74033672 0.165 ENST00000307365.3
DDIT4
DNA-damage-inducible transcript 4
chr22_+_40390930 0.164 ENST00000333407.6
FAM83F
family with sequence similarity 83, member F
chr11_-_46142948 0.161 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr5_+_157170703 0.160 ENST00000286307.5
LSM11
LSM11, U7 small nuclear RNA associated
chr15_-_52861394 0.159 ENST00000563277.1
ENST00000566423.1
ARPP19

cAMP-regulated phosphoprotein, 19kDa

chrX_+_9431324 0.158 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X





transducin (beta)-like 1X-linked





chr9_-_133814455 0.158 ENST00000448616.1
FIBCD1
fibrinogen C domain containing 1
chr7_+_106809406 0.158 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
HBP1



HMG-box transcription factor 1



chr7_+_7811992 0.157 ENST00000406829.1
RPA3-AS1
RPA3 antisense RNA 1
chr13_-_31038370 0.156 ENST00000399489.1
ENST00000339872.4
HMGB1

high mobility group box 1

chr2_-_44588893 0.155 ENST00000409272.1
ENST00000410081.1
ENST00000541738.1
PREPL


prolyl endopeptidase-like


chr4_+_77870856 0.155 ENST00000264893.6
ENST00000502584.1
ENST00000510641.1
SEPT11


septin 11


chr8_+_98656336 0.154 ENST00000336273.3
MTDH
metadherin
chr19_+_32896697 0.152 ENST00000586987.1
DPY19L3
dpy-19-like 3 (C. elegans)
chr13_-_23949671 0.151 ENST00000402364.1
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr15_+_79165151 0.149 ENST00000331268.5
MORF4L1
mortality factor 4 like 1
chr9_+_91003271 0.147 ENST00000375859.3
ENST00000541629.1
SPIN1

spindlin 1

chr22_+_30792846 0.146 ENST00000312932.9
ENST00000428195.1
SEC14L2

SEC14-like 2 (S. cerevisiae)

chr5_+_173315283 0.142 ENST00000265085.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr1_-_209979375 0.141 ENST00000367021.3
IRF6
interferon regulatory factor 6
chr9_-_74980113 0.141 ENST00000376962.5
ENST00000376960.4
ENST00000237937.3
ZFAND5


zinc finger, AN1-type domain 5


chr15_+_75118888 0.140 ENST00000395018.4
CPLX3
complexin 3
chr2_+_46844290 0.138 ENST00000238892.3
CRIPT
cysteine-rich PDZ-binding protein
chr12_+_69004619 0.129 ENST00000250559.9
ENST00000393436.5
ENST00000425247.2
ENST00000489473.2
ENST00000422358.2
ENST00000541167.1
ENST00000538283.1
ENST00000341355.5
ENST00000537460.1
ENST00000450214.2
ENST00000545270.1
ENST00000538980.1
ENST00000542018.1
ENST00000543393.1
RAP1B













RAP1B, member of RAS oncogene family













chr5_-_89770582 0.129 ENST00000316610.6
MBLAC2
metallo-beta-lactamase domain containing 2
chr3_-_79068594 0.129 ENST00000436010.2
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr1_+_151043070 0.122 ENST00000368918.3
ENST00000368917.1
GABPB2

GA binding protein transcription factor, beta subunit 2

chr6_+_125283566 0.122 ENST00000521654.2
RNF217
ring finger protein 217
chr2_-_161350305 0.118 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr13_+_58206655 0.117 ENST00000377918.3
PCDH17
protocadherin 17
chr9_-_107690420 0.116 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ABCA1


ATP-binding cassette, sub-family A (ABC1), member 1


chr11_+_120207787 0.116 ENST00000397843.2
ENST00000356641.3
ARHGEF12

Rho guanine nucleotide exchange factor (GEF) 12

chr11_-_64612041 0.115 ENST00000342711.5
CDC42BPG
CDC42 binding protein kinase gamma (DMPK-like)
chr14_-_103523745 0.114 ENST00000361246.2
CDC42BPB
CDC42 binding protein kinase beta (DMPK-like)
chr17_+_29718642 0.114 ENST00000325874.8
RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr3_+_52017454 0.113 ENST00000476854.1
ENST00000476351.1
ENST00000494103.1
ENST00000404366.2
ENST00000469863.1
ACY1




aminoacylase 1




chr6_-_159239257 0.112 ENST00000337147.7
ENST00000392177.4
EZR

ezrin

chrX_-_24045303 0.110 ENST00000328046.8
KLHL15
kelch-like family member 15
chr5_+_133706865 0.110 ENST00000265339.2
UBE2B
ubiquitin-conjugating enzyme E2B
chr10_+_71561630 0.109 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
COL13A1








collagen, type XIII, alpha 1








chr6_-_109703663 0.108 ENST00000368961.5
CD164
CD164 molecule, sialomucin
chr5_+_65222299 0.108 ENST00000284037.5
ERBB2IP
erbb2 interacting protein
chr17_-_4269768 0.107 ENST00000396981.2
UBE2G1
ubiquitin-conjugating enzyme E2G 1
chr7_+_114055052 0.106 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2







forkhead box P2







chr1_-_53018654 0.106 ENST00000257177.4
ENST00000355809.4
ENST00000528642.1
ENST00000470626.1
ENST00000371544.3
ZCCHC11




zinc finger, CCHC domain containing 11




chr3_+_140660634 0.103 ENST00000446041.2
ENST00000507429.1
ENST00000324194.6
SLC25A36


solute carrier family 25 (pyrimidine nucleotide carrier ), member 36


chr2_+_191273052 0.102 ENST00000417958.1
ENST00000432036.1
ENST00000392328.1
MFSD6


major facilitator superfamily domain containing 6


chr3_-_141868357 0.102 ENST00000489671.1
ENST00000475734.1
ENST00000467072.1
ENST00000499676.2
TFDP2



transcription factor Dp-2 (E2F dimerization partner 2)



chr9_+_115513003 0.101 ENST00000374232.3
SNX30
sorting nexin family member 30
chr8_+_17013515 0.100 ENST00000262096.8
ZDHHC2
zinc finger, DHHC-type containing 2
chr2_+_118846008 0.097 ENST00000245787.4
INSIG2
insulin induced gene 2
chr8_+_42010464 0.097 ENST00000518421.1
ENST00000174653.3
ENST00000396926.3
ENST00000521280.1
ENST00000522288.1
AP3M2




adaptor-related protein complex 3, mu 2 subunit




chr7_+_107301065 0.094 ENST00000265715.3
SLC26A4
solute carrier family 26 (anion exchanger), member 4
chr12_-_25403737 0.093 ENST00000256078.4
ENST00000556131.1
ENST00000311936.3
ENST00000557334.1
KRAS



Kirsten rat sarcoma viral oncogene homolog



chr15_-_83316254 0.093 ENST00000567678.1
ENST00000450751.2
CPEB1

cytoplasmic polyadenylation element binding protein 1

chr9_-_139922631 0.093 ENST00000341511.6
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr17_+_48172639 0.092 ENST00000503176.1
ENST00000503614.1
PDK2

pyruvate dehydrogenase kinase, isozyme 2

chr10_-_113943447 0.092 ENST00000369425.1
ENST00000348367.4
ENST00000423155.1
GPAM


glycerol-3-phosphate acyltransferase, mitochondrial


chr20_+_11871371 0.085 ENST00000254977.3
BTBD3
BTB (POZ) domain containing 3
chr19_+_1752372 0.085 ENST00000382349.4
ONECUT3
one cut homeobox 3
chr8_+_37654424 0.084 ENST00000315215.7
GPR124
G protein-coupled receptor 124
chr19_-_33555780 0.084 ENST00000254260.3
ENST00000400226.4
RHPN2

rhophilin, Rho GTPase binding protein 2

chr17_-_45266542 0.084 ENST00000531206.1
ENST00000527547.1
ENST00000446365.2
ENST00000575483.1
ENST00000066544.3
CDC27




cell division cycle 27




chr10_+_75936444 0.084 ENST00000372734.3
ENST00000541550.1
ADK

adenosine kinase

chr17_+_20059302 0.083 ENST00000395530.2
SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr7_+_91875508 0.083 ENST00000265742.3
ANKIB1
ankyrin repeat and IBR domain containing 1
chr19_-_33166045 0.081 ENST00000586693.3
ENST00000587352.1
ENST00000586463.1
ENST00000306065.4
ANKRD27



ankyrin repeat domain 27 (VPS9 domain)



chrX_+_12993202 0.078 ENST00000451311.2
ENST00000380636.1
TMSB4X

thymosin beta 4, X-linked

chr3_-_133969437 0.078 ENST00000460933.1
ENST00000296084.4
RYK

receptor-like tyrosine kinase

chr3_-_72496035 0.078 ENST00000477973.2
RYBP
RING1 and YY1 binding protein
chr14_-_45431091 0.078 ENST00000579157.1
ENST00000396128.4
ENST00000556500.1
KLHL28


kelch-like family member 28


chr8_-_124553437 0.078 ENST00000517956.1
ENST00000443022.2
FBXO32

F-box protein 32

chr15_+_66679155 0.076 ENST00000307102.5
MAP2K1
mitogen-activated protein kinase kinase 1
chr11_-_77532050 0.076 ENST00000308488.6
RSF1
remodeling and spacing factor 1
chr10_+_72164135 0.075 ENST00000373218.4
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr2_+_114647504 0.074 ENST00000263238.2
ACTR3
ARP3 actin-related protein 3 homolog (yeast)
chr3_+_98451275 0.074 ENST00000265261.6
ENST00000497008.1
ST3GAL6

ST3 beta-galactoside alpha-2,3-sialyltransferase 6

chr9_-_114246635 0.073 ENST00000338205.5
KIAA0368
KIAA0368
chr1_+_16174280 0.073 ENST00000375759.3
SPEN
spen family transcriptional repressor
chr8_-_11725549 0.072 ENST00000505496.2
ENST00000534636.1
ENST00000524500.1
ENST00000345125.3
ENST00000453527.2
ENST00000527215.2
ENST00000532392.1
ENST00000533455.1
ENST00000534510.1
ENST00000530640.2
ENST00000531089.1
ENST00000532656.2
ENST00000531502.1
ENST00000434271.1
ENST00000353047.6
CTSB














cathepsin B














chr16_-_23521710 0.071 ENST00000562117.1
ENST00000567468.1
ENST00000562944.1
ENST00000309859.4
GGA2



golgi-associated, gamma adaptin ear containing, ARF binding protein 2



chr2_+_204192942 0.070 ENST00000295851.5
ENST00000261017.5
ABI2

abl-interactor 2

chrX_+_122993827 0.070 ENST00000371199.3
XIAP
X-linked inhibitor of apoptosis
chr20_-_56284816 0.068 ENST00000395819.3
ENST00000341744.3
PMEPA1

prostate transmembrane protein, androgen induced 1

chr15_+_41136216 0.068 ENST00000562057.1
ENST00000344051.4
SPINT1

serine peptidase inhibitor, Kunitz type 1

chr1_+_109792641 0.067 ENST00000271332.3
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2
chr17_+_66508537 0.067 ENST00000392711.1
ENST00000585427.1
ENST00000589228.1
ENST00000536854.2
ENST00000588702.1
ENST00000589309.1
PRKAR1A





protein kinase, cAMP-dependent, regulatory, type I, alpha





chr12_-_92539614 0.066 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr10_+_134351319 0.065 ENST00000368594.3
ENST00000368593.3
INPP5A

inositol polyphosphate-5-phosphatase, 40kDa

chr2_-_54197915 0.065 ENST00000404125.1
PSME4
proteasome (prosome, macropain) activator subunit 4
chr1_-_47134101 0.065 ENST00000576409.1
ATPAF1
ATP synthase mitochondrial F1 complex assembly factor 1
chr15_-_51058005 0.065 ENST00000261854.5
SPPL2A
signal peptide peptidase like 2A
chr16_-_4166186 0.064 ENST00000294016.3
ADCY9
adenylate cyclase 9
chr12_-_57630873 0.063 ENST00000556732.1
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr1_+_24286287 0.061 ENST00000334351.7
ENST00000374468.1
PNRC2

proline-rich nuclear receptor coactivator 2

chr6_-_57087042 0.061 ENST00000317483.3
RAB23
RAB23, member RAS oncogene family
chr3_+_178866199 0.061 ENST00000263967.3
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr1_+_203595903 0.060 ENST00000367218.3
ENST00000367219.3
ENST00000391954.2
ATP2B4


ATPase, Ca++ transporting, plasma membrane 4


chr9_+_79074068 0.060 ENST00000444201.2
ENST00000376730.4
GCNT1

glucosaminyl (N-acetyl) transferase 1, core 2

chr13_+_103249322 0.060 ENST00000376065.4
ENST00000376052.3
TPP2

tripeptidyl peptidase II

chr1_+_201798269 0.059 ENST00000361565.4
IPO9
importin 9
chr8_-_119634141 0.056 ENST00000409003.4
ENST00000526328.1
ENST00000314727.4
ENST00000526765.1
SAMD12



sterile alpha motif domain containing 12



chr10_+_63661053 0.056 ENST00000279873.7
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr12_-_118541743 0.055 ENST00000359236.5
VSIG10
V-set and immunoglobulin domain containing 10
chr5_-_171433819 0.055 ENST00000296933.6
FBXW11
F-box and WD repeat domain containing 11
chr7_-_47621736 0.054 ENST00000311160.9
TNS3
tensin 3
chr2_+_203499901 0.054 ENST00000303116.6
ENST00000392238.2
FAM117B

family with sequence similarity 117, member B

chr8_+_17354587 0.053 ENST00000494857.1
ENST00000522656.1
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr5_-_77844974 0.053 ENST00000515007.2
LHFPL2
lipoma HMGIC fusion partner-like 2
chr3_-_196230590 0.053 ENST00000318037.3
RNF168
ring finger protein 168, E3 ubiquitin protein ligase
chr5_-_172756506 0.053 ENST00000265087.4
STC2
stanniocalcin 2
chr15_-_35280426 0.051 ENST00000559564.1
ENST00000356321.4
ZNF770

zinc finger protein 770

chr4_-_110223799 0.051 ENST00000399132.1
ENST00000399126.1
ENST00000505591.1
COL25A1


collagen, type XXV, alpha 1


chr3_+_57261743 0.050 ENST00000288266.3
APPL1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr12_-_12419703 0.050 ENST00000543091.1
ENST00000261349.4
LRP6

low density lipoprotein receptor-related protein 6

chr9_+_2015335 0.050 ENST00000349721.2
ENST00000357248.2
ENST00000450198.1
SMARCA2


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2


chr15_-_65282274 0.050 ENST00000204566.2
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr2_-_220094294 0.049 ENST00000436856.1
ENST00000428226.1
ENST00000409422.1
ENST00000431715.1
ENST00000457841.1
ENST00000439812.1
ENST00000361242.4
ENST00000396761.2
ATG9A







autophagy related 9A







chr17_+_30677136 0.049 ENST00000394670.4
ENST00000321233.6
ENST00000394673.2
ENST00000341711.6
ENST00000579634.1
ENST00000580759.1
ENST00000342555.6
ENST00000577908.1
ENST00000394679.5
ENST00000582165.1
ZNF207









zinc finger protein 207









chr1_-_155532484 0.049 ENST00000368346.3
ENST00000548830.1
ASH1L

ash1 (absent, small, or homeotic)-like (Drosophila)

chr6_-_79787902 0.048 ENST00000275034.4
PHIP
pleckstrin homology domain interacting protein
chr3_-_49449350 0.048 ENST00000454011.2
ENST00000445425.1
ENST00000422781.1
RHOA


ras homolog family member A


chr1_+_110009215 0.048 ENST00000369872.3
SYPL2
synaptophysin-like 2
chr6_-_8102714 0.047 ENST00000502429.1
ENST00000429723.2
ENST00000507463.1
ENST00000379715.5
EEF1E1



eukaryotic translation elongation factor 1 epsilon 1



chr19_+_11466062 0.046 ENST00000251473.5
ENST00000591329.1
ENST00000586380.1
DKFZP761J1410


Lipid phosphate phosphatase-related protein type 2


chr6_+_117996621 0.046 ENST00000368494.3
NUS1
nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
chr15_-_41624685 0.046 ENST00000560640.1
ENST00000220514.3
OIP5

Opa interacting protein 5

chr4_+_86396265 0.045 ENST00000395184.1
ARHGAP24
Rho GTPase activating protein 24
chr18_+_67956135 0.045 ENST00000397942.3
SOCS6
suppressor of cytokine signaling 6
chr13_-_45915221 0.045 ENST00000309246.5
ENST00000379060.4
ENST00000379055.1
ENST00000527226.1
ENST00000379056.1
TPT1




tumor protein, translationally-controlled 1




chr9_-_116061476 0.044 ENST00000441031.3
RNF183
ring finger protein 183
chr1_+_174769006 0.043 ENST00000489615.1
RABGAP1L
RAB GTPase activating protein 1-like
chr5_+_17217669 0.043 ENST00000322611.3
BASP1
brain abundant, membrane attached signal protein 1
chrX_-_102942961 0.043 ENST00000434230.1
ENST00000418819.1
ENST00000360458.1
MORF4L2


mortality factor 4 like 2


chr2_-_208890218 0.042 ENST00000457206.1
ENST00000427836.2
ENST00000389247.4
PLEKHM3


pleckstrin homology domain containing, family M, member 3


chr17_-_63052929 0.042 ENST00000439174.2
GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr17_+_2496971 0.041 ENST00000397195.5
PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr8_+_95835438 0.040 ENST00000521860.1
ENST00000519457.1
ENST00000519053.1
ENST00000523731.1
ENST00000447247.1
INTS8




integrator complex subunit 8




chr16_+_8768422 0.040 ENST00000268251.8
ENST00000564714.1
ABAT

4-aminobutyrate aminotransferase


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.1 0.6 GO:1905075 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.1 0.4 GO:0046041 ITP metabolic process(GO:0046041)
0.1 0.3 GO:0071106 coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.1 0.3 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 0.5 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.2 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 0.3 GO:0010040 response to iron(II) ion(GO:0010040)
0.1 0.2 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.1 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.3 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.1 0.3 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.4 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.7 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.2 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.0 0.1 GO:1990709 presynaptic active zone organization(GO:1990709)
0.0 0.1 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.1 GO:1903450 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.4 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.2 GO:2000568 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.2 GO:0097327 response to antineoplastic agent(GO:0097327) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0 0.2 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.0 0.1 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.3 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.2 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.2 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.3 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.1 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 0.1 GO:0033242 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) negative regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901205) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.1 GO:0060352 cell adhesion molecule production(GO:0060352)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.9 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:1903410 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.0 0.1 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:2000053 canonical Wnt signaling pathway involved in neural crest cell differentiation(GO:0044335) Wnt signaling pathway involved in somitogenesis(GO:0090244) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.1 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.2 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.1 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.1 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.0 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.3 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.4 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.0 GO:2001076 thorax and anterior abdomen determination(GO:0007356) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.6 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.7 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.4 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.3 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 0.5 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1 0.3 GO:0051538 iron-responsive element binding(GO:0030350) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 0.3 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 0.4 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.3 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 0.6 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025) type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.3 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.2 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.2 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.2 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.2 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 0.2 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.2 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.2 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.3 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.1 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.0 GO:0070905 serine binding(GO:0070905)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.0 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0032451 demethylase activity(GO:0032451) histone demethylase activity(GO:0032452)
0.0 0.6 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.1 GO:0005289 high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292)
0.0 0.0 GO:0031752 D5 dopamine receptor binding(GO:0031752)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID_ALK1_PATHWAY ALK1 signaling events
0.0 0.5 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.7 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.2 REACTOME_ARMS_MEDIATED_ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.3 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta