Motif ID: TP63

Z-value: 0.730


Transcription factors associated with TP63:

Gene SymbolEntrez IDGene Name
TP63 ENSG00000073282.8 TP63

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TP63hg19_v2_chr3_+_189349162_1893493050.186.5e-01Click!


Activity profile for motif TP63.

activity profile for motif TP63


Sorted Z-values histogram for motif TP63

Sorted Z-values for motif TP63



Network of associatons between targets according to the STRING database.



First level regulatory network of TP63

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_78492927 1.282 ENST00000334286.5
EDNRB
endothelin receptor type B
chr12_-_15114603 1.253 ENST00000228945.4
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr12_-_15114492 1.123 ENST00000541546.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr13_-_78492955 1.033 ENST00000446573.1
EDNRB
endothelin receptor type B
chr12_-_15114658 0.697 ENST00000542276.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr2_+_69201705 0.678 ENST00000377938.2
GKN1
gastrokine 1
chr15_+_101417919 0.597 ENST00000561338.1
ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr18_+_57567180 0.507 ENST00000316660.6
ENST00000269518.9
PMAIP1

phorbol-12-myristate-13-acetate-induced protein 1

chr12_-_15114191 0.488 ENST00000541380.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr14_+_51955831 0.458 ENST00000356218.4
FRMD6
FERM domain containing 6
chr1_-_26197744 0.458 ENST00000374296.3
PAQR7
progestin and adipoQ receptor family member VII
chr19_-_3500635 0.442 ENST00000250937.3
DOHH
deoxyhypusine hydroxylase/monooxygenase
chr8_+_22437664 0.425 ENST00000436754.1
ENST00000426493.1
ENST00000429812.1
PDLIM2


PDZ and LIM domain 2 (mystique)


chr5_-_94417562 0.381 ENST00000505465.1
MCTP1
multiple C2 domains, transmembrane 1
chr1_-_153588334 0.370 ENST00000476873.1
S100A14
S100 calcium binding protein A14
chr19_-_4717835 0.367 ENST00000599248.1
DPP9
dipeptidyl-peptidase 9
chr15_-_89456593 0.348 ENST00000558029.1
ENST00000539437.1
ENST00000542878.1
ENST00000268151.7
ENST00000566497.1
MFGE8




milk fat globule-EGF factor 8 protein




chrX_-_153602991 0.340 ENST00000369850.3
ENST00000422373.1
FLNA

filamin A, alpha

chr19_-_19051103 0.335 ENST00000542541.2
ENST00000433218.2
HOMER3

homer homolog 3 (Drosophila)

chr11_-_10920838 0.333 ENST00000503469.2
CTD-2003C8.2
CTD-2003C8.2
chr2_+_131369054 0.330 ENST00000409602.1
POTEJ
POTE ankyrin domain family, member J
chr1_-_150738261 0.328 ENST00000448301.2
ENST00000368985.3
CTSS

cathepsin S

chr6_-_30712313 0.320 ENST00000376377.2
ENST00000259874.5
IER3

immediate early response 3

chr5_-_94417314 0.309 ENST00000505208.1
MCTP1
multiple C2 domains, transmembrane 1
chr5_+_6766004 0.279 ENST00000506093.1
RP11-332J15.3
RP11-332J15.3
chr8_+_22437965 0.277 ENST00000409141.1
ENST00000265810.4
PDLIM2

PDZ and LIM domain 2 (mystique)

chr2_-_151344172 0.276 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3


Rho family GTPase 3


chr5_-_94417339 0.273 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1


multiple C2 domains, transmembrane 1


chrX_-_153583257 0.270 ENST00000438732.1
FLNA
filamin A, alpha
chr22_+_36044411 0.268 ENST00000409652.4
APOL6
apolipoprotein L, 6
chr11_+_65686728 0.265 ENST00000312515.2
ENST00000525501.1
DRAP1

DR1-associated protein 1 (negative cofactor 2 alpha)

chr4_+_671711 0.255 ENST00000400159.2
MYL5
myosin, light chain 5, regulatory
chr7_+_100466433 0.252 ENST00000429658.1
TRIP6
thyroid hormone receptor interactor 6
chr15_-_89456630 0.251 ENST00000268150.8
MFGE8
milk fat globule-EGF factor 8 protein
chr13_+_76334498 0.246 ENST00000534657.1
LMO7
LIM domain 7
chr12_-_10321754 0.239 ENST00000539518.1
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
chr8_+_67341239 0.236 ENST00000320270.2
RRS1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr1_-_114447620 0.234 ENST00000369569.1
ENST00000432415.1
ENST00000369571.2
AP4B1


adaptor-related protein complex 4, beta 1 subunit


chr19_+_18496957 0.233 ENST00000252809.3
GDF15
growth differentiation factor 15
chr7_-_139756791 0.232 ENST00000489809.1
PARP12
poly (ADP-ribose) polymerase family, member 12
chr1_-_114447683 0.227 ENST00000256658.4
ENST00000369564.1
AP4B1

adaptor-related protein complex 4, beta 1 subunit

chr14_-_100046444 0.225 ENST00000554996.1
CCDC85C
coiled-coil domain containing 85C
chr1_+_38158090 0.224 ENST00000373055.1
ENST00000327331.2
CDCA8

cell division cycle associated 8

chr13_+_76334567 0.221 ENST00000321797.8
LMO7
LIM domain 7
chr16_-_57837129 0.220 ENST00000562984.1
ENST00000564891.1
KIFC3

kinesin family member C3

chr12_+_110172572 0.214 ENST00000358906.3
FAM222A
family with sequence similarity 222, member A
chr1_+_110198689 0.210 ENST00000369836.4
GSTM4
glutathione S-transferase mu 4
chr1_-_38157877 0.206 ENST00000477060.1
ENST00000491981.1
ENST00000488137.1
C1orf109


chromosome 1 open reading frame 109


chr16_+_66413128 0.200 ENST00000563425.2
CDH5
cadherin 5, type 2 (vascular endothelium)
chr11_-_71823266 0.198 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
ANAPC15


anaphase promoting complex subunit 15


chr3_+_69915363 0.192 ENST00000451708.1
MITF
microphthalmia-associated transcription factor
chr11_-_71814422 0.187 ENST00000278671.5
LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr9_+_116298778 0.186 ENST00000462143.1
RGS3
regulator of G-protein signaling 3
chr8_+_74206829 0.186 ENST00000240285.5
RDH10
retinol dehydrogenase 10 (all-trans)
chr5_+_153570319 0.181 ENST00000377661.2
GALNT10
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr11_-_7985193 0.180 ENST00000328600.2
NLRP10
NLR family, pyrin domain containing 10
chr5_+_153570285 0.179 ENST00000425427.2
ENST00000297107.6
GALNT10

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)

chr3_+_69915385 0.178 ENST00000314589.5
MITF
microphthalmia-associated transcription factor
chr14_-_94595993 0.174 ENST00000238609.3
IFI27L2
interferon, alpha-inducible protein 27-like 2
chr15_-_72514866 0.172 ENST00000562997.1
PKM
pyruvate kinase, muscle
chr2_+_101179152 0.172 ENST00000264254.6
PDCL3
phosducin-like 3
chr2_+_68384976 0.169 ENST00000263657.2
PNO1
partner of NOB1 homolog (S. cerevisiae)
chr21_-_33104367 0.168 ENST00000286835.7
ENST00000399804.1
SCAF4

SR-related CTD-associated factor 4

chr11_+_61891445 0.168 ENST00000394818.3
ENST00000533896.1
ENST00000278849.4
INCENP


inner centromere protein antigens 135/155kDa


chr1_-_94312706 0.165 ENST00000370244.1
BCAR3
breast cancer anti-estrogen resistance 3
chr17_+_38337491 0.164 ENST00000538981.1
RAPGEFL1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr19_+_49497121 0.164 ENST00000413176.2
RUVBL2
RuvB-like AAA ATPase 2
chr11_-_71814276 0.164 ENST00000538404.1
ENST00000535107.1
ENST00000545249.1
LAMTOR1


late endosomal/lysosomal adaptor, MAPK and MTOR activator 1


chr12_-_15942503 0.161 ENST00000281172.5
EPS8
epidermal growth factor receptor pathway substrate 8
chr12_-_96184533 0.160 ENST00000343702.4
ENST00000344911.4
NTN4

netrin 4

chr20_-_6103666 0.160 ENST00000536936.1
FERMT1
fermitin family member 1
chr22_+_38201114 0.158 ENST00000340857.2
H1F0
H1 histone family, member 0
chr19_+_44081344 0.157 ENST00000599207.1
PINLYP
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr5_+_72861560 0.157 ENST00000296792.4
ENST00000509005.1
ENST00000543251.1
ENST00000508686.1
ENST00000508491.1
UTP15




UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)




chrX_-_129244336 0.155 ENST00000434609.1
ELF4
E74-like factor 4 (ets domain transcription factor)
chr15_+_32907691 0.155 ENST00000361627.3
ENST00000567348.1
ENST00000563864.1
ENST00000543522.1
ARHGAP11A



Rho GTPase activating protein 11A



chr6_-_33663474 0.154 ENST00000594414.1
SBP1
SBP1; Uncharacterized protein
chr17_+_21279509 0.152 ENST00000583088.1
KCNJ12
potassium inwardly-rectifying channel, subfamily J, member 12
chr17_+_78397320 0.151 ENST00000521634.1
ENST00000572886.1
ENDOV

endonuclease V

chr17_+_8191815 0.145 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RANGRF



RAN guanine nucleotide release factor



chr2_+_113299990 0.145 ENST00000537335.1
ENST00000417433.2
POLR1B

polymerase (RNA) I polypeptide B, 128kDa

chr10_-_75532373 0.138 ENST00000595757.1
AC022400.2
Uncharacterized protein; cDNA FLJ44715 fis, clone BRACE3021430
chr4_+_71554196 0.137 ENST00000254803.2
UTP3
UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
chrX_+_2670066 0.137 ENST00000381174.5
ENST00000419513.2
ENST00000426774.1
XG


Xg blood group


chr16_-_57798253 0.136 ENST00000565270.1
KIFC3
kinesin family member C3
chr19_+_535835 0.135 ENST00000607527.1
ENST00000606065.1
CDC34

cell division cycle 34

chr14_+_52456193 0.133 ENST00000261700.3
C14orf166
chromosome 14 open reading frame 166
chr12_+_119616447 0.131 ENST00000281938.2
HSPB8
heat shock 22kDa protein 8
chr3_+_47844399 0.129 ENST00000446256.2
ENST00000445061.1
DHX30

DEAH (Asp-Glu-Ala-His) box helicase 30

chr18_-_49557 0.128 ENST00000308911.6
RP11-683L23.1
Tubulin beta-8 chain-like protein LOC260334
chr2_+_112813134 0.127 ENST00000452614.1
TMEM87B
transmembrane protein 87B
chr5_-_132073210 0.126 ENST00000378735.1
ENST00000378746.4
KIF3A

kinesin family member 3A

chr5_+_125935960 0.125 ENST00000297540.4
PHAX
phosphorylated adaptor for RNA export
chr19_+_4007644 0.125 ENST00000262971.2
PIAS4
protein inhibitor of activated STAT, 4
chr20_+_34679725 0.124 ENST00000432589.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr19_+_48824711 0.123 ENST00000599704.1
EMP3
epithelial membrane protein 3
chr2_+_198365122 0.123 ENST00000604458.1
HSPE1-MOB4
HSPE1-MOB4 readthrough
chr12_-_58159361 0.121 ENST00000546567.1
CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr15_-_72523924 0.120 ENST00000566809.1
ENST00000567087.1
ENST00000569050.1
ENST00000568883.1
PKM



pyruvate kinase, muscle



chr20_+_5731083 0.119 ENST00000445603.1
ENST00000442185.1
C20orf196

chromosome 20 open reading frame 196

chr7_-_110174754 0.118 ENST00000435466.1
AC003088.1
AC003088.1
chr22_+_50628999 0.117 ENST00000395827.1
TRABD
TraB domain containing
chr5_+_125798031 0.115 ENST00000502348.1
GRAMD3
GRAM domain containing 3
chr11_+_64073699 0.112 ENST00000405666.1
ENST00000468670.1
ESRRA

estrogen-related receptor alpha

chr9_+_91606355 0.111 ENST00000358157.2
S1PR3
sphingosine-1-phosphate receptor 3
chr14_+_52456327 0.111 ENST00000556760.1
C14orf166
chromosome 14 open reading frame 166
chr11_-_10920714 0.110 ENST00000533941.1
CTD-2003C8.2
CTD-2003C8.2
chr19_-_47288162 0.109 ENST00000594991.1
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr3_-_33700589 0.109 ENST00000461133.3
ENST00000496954.2
CLASP2

cytoplasmic linker associated protein 2

chr14_-_37641618 0.108 ENST00000555449.1
SLC25A21
solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
chr8_-_23021533 0.107 ENST00000312584.3
TNFRSF10D
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
chr9_+_134065506 0.106 ENST00000483497.2
NUP214
nucleoporin 214kDa
chr12_+_69202795 0.104 ENST00000539479.1
ENST00000393415.3
ENST00000523991.1
ENST00000543323.1
ENST00000393416.2
MDM2




MDM2 oncogene, E3 ubiquitin protein ligase




chr4_+_24661479 0.103 ENST00000569621.1
RP11-496D24.2
RP11-496D24.2
chr16_+_718147 0.103 ENST00000561929.1
RHOT2
ras homolog family member T2
chr2_-_27603582 0.102 ENST00000323703.6
ENST00000436006.1
ZNF513

zinc finger protein 513

chr11_-_1330834 0.102 ENST00000525159.1
ENST00000317204.6
ENST00000542915.1
ENST00000527938.1
ENST00000530541.1
ENST00000263646.7
TOLLIP





toll interacting protein





chrX_+_48334549 0.102 ENST00000019019.2
ENST00000348411.2
ENST00000396894.4
FTSJ1


FtsJ RNA methyltransferase homolog 1 (E. coli)


chr7_-_75115548 0.102 ENST00000453279.2
POM121C
POM121 transmembrane nucleoporin C
chr19_-_5292781 0.102 ENST00000586065.1
PTPRS
protein tyrosine phosphatase, receptor type, S
chr17_-_76824975 0.102 ENST00000586066.2
USP36
ubiquitin specific peptidase 36
chr9_+_134065519 0.101 ENST00000531600.1
NUP214
nucleoporin 214kDa
chr2_-_47168850 0.099 ENST00000409207.1
MCFD2
multiple coagulation factor deficiency 2
chr5_+_179247759 0.099 ENST00000389805.4
ENST00000504627.1
ENST00000402874.3
ENST00000510187.1
SQSTM1



sequestosome 1



chr10_-_105212141 0.098 ENST00000369788.3
CALHM2
calcium homeostasis modulator 2
chr15_+_74466744 0.098 ENST00000560862.1
ENST00000395118.1
ISLR

immunoglobulin superfamily containing leucine-rich repeat

chr19_-_53426700 0.098 ENST00000596623.1
ZNF888
zinc finger protein 888
chr10_+_5726764 0.098 ENST00000328090.5
ENST00000496681.1
FAM208B

family with sequence similarity 208, member B

chr20_+_34894247 0.097 ENST00000373913.3
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr12_-_122711968 0.096 ENST00000485724.1
DIABLO
diablo, IAP-binding mitochondrial protein
chr12_-_96184913 0.096 ENST00000538383.1
NTN4
netrin 4
chr16_+_1832902 0.094 ENST00000262302.9
ENST00000563136.1
ENST00000565987.1
ENST00000543305.1
ENST00000568287.1
ENST00000565134.1
NUBP2





nucleotide binding protein 2





chr19_-_10613421 0.093 ENST00000393623.2
KEAP1
kelch-like ECH-associated protein 1
chr3_-_9005118 0.093 ENST00000264926.2
RAD18
RAD18 homolog (S. cerevisiae)
chr12_+_51347705 0.092 ENST00000398455.3
HIGD1C
HIG1 hypoxia inducible domain family, member 1C
chr14_+_24779340 0.092 ENST00000533293.1
ENST00000543919.1
LTB4R2

leukotriene B4 receptor 2

chr1_-_1356719 0.091 ENST00000520296.1
ANKRD65
ankyrin repeat domain 65
chr2_-_130878140 0.089 ENST00000360967.5
ENST00000361163.4
ENST00000357462.5
POTEF


POTE ankyrin domain family, member F


chr9_+_131218408 0.089 ENST00000351030.3
ENST00000604420.1
ENST00000535026.1
ENST00000448249.3
ENST00000393527.3
ODF2




outer dense fiber of sperm tails 2




chr9_-_35619539 0.088 ENST00000396757.1
CD72
CD72 molecule
chr17_-_18430160 0.088 ENST00000392176.3
FAM106A
family with sequence similarity 106, member A
chr13_+_48611665 0.087 ENST00000258662.2
NUDT15
nudix (nucleoside diphosphate linked moiety X)-type motif 15
chr6_-_101329157 0.087 ENST00000369143.2
ASCC3
activating signal cointegrator 1 complex subunit 3
chr1_-_1356628 0.087 ENST00000442470.1
ENST00000537107.1
ANKRD65

ankyrin repeat domain 65

chr2_-_74726710 0.087 ENST00000377566.4
LBX2
ladybird homeobox 2
chr3_-_45017609 0.087 ENST00000342790.4
ENST00000424952.2
ENST00000296127.3
ENST00000455235.1
ZDHHC3



zinc finger, DHHC-type containing 3



chrX_-_45710920 0.086 ENST00000456532.1
RP5-1158E12.3
RP5-1158E12.3
chr20_+_57264187 0.086 ENST00000525967.1
ENST00000525817.1
NPEPL1

aminopeptidase-like 1

chr15_-_72767490 0.085 ENST00000565181.1
RP11-1007O24.3
RP11-1007O24.3
chr10_+_124913930 0.085 ENST00000368858.5
BUB3
BUB3 mitotic checkpoint protein
chr13_+_42846272 0.084 ENST00000025301.2
AKAP11
A kinase (PRKA) anchor protein 11
chr8_-_22926526 0.084 ENST00000347739.3
ENST00000542226.1
TNFRSF10B

tumor necrosis factor receptor superfamily, member 10b

chr16_+_28834303 0.084 ENST00000340394.8
ENST00000325215.6
ENST00000395547.2
ENST00000336783.4
ENST00000382686.4
ENST00000564304.1
ATXN2L





ataxin 2-like





chr7_+_79763271 0.084 ENST00000442586.1
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr16_+_57653854 0.083 ENST00000568908.1
ENST00000568909.1
ENST00000566778.1
ENST00000561988.1
GPR56



G protein-coupled receptor 56



chr4_-_40516560 0.082 ENST00000513473.1
RBM47
RNA binding motif protein 47
chr17_+_75450075 0.081 ENST00000592951.1
SEPT9
septin 9
chr11_-_68611721 0.080 ENST00000561996.1
CPT1A
carnitine palmitoyltransferase 1A (liver)
chr6_+_32939964 0.080 ENST00000607833.1
BRD2
bromodomain containing 2
chr3_+_184080387 0.079 ENST00000455712.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr8_-_22926623 0.078 ENST00000276431.4
TNFRSF10B
tumor necrosis factor receptor superfamily, member 10b
chr14_-_37642016 0.077 ENST00000331299.5
SLC25A21
solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
chr11_-_64889649 0.077 ENST00000434372.2
FAU
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
chr11_+_76493294 0.077 ENST00000533752.1
TSKU
tsukushi, small leucine rich proteoglycan
chr13_-_50367057 0.076 ENST00000261667.3
KPNA3
karyopherin alpha 3 (importin alpha 4)
chr22_+_37959647 0.076 ENST00000415670.1
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr2_-_216003127 0.075 ENST00000412081.1
ENST00000272895.7
ABCA12

ATP-binding cassette, sub-family A (ABC1), member 12

chr4_+_2794750 0.075 ENST00000452765.2
ENST00000389838.2
SH3BP2

SH3-domain binding protein 2

chr8_+_117778736 0.075 ENST00000309822.2
ENST00000357148.3
ENST00000517814.1
ENST00000517820.1
UTP23



UTP23, small subunit (SSU) processome component, homolog (yeast)



chr12_+_69202975 0.074 ENST00000544561.1
ENST00000393410.1
ENST00000299252.4
ENST00000360430.2
ENST00000517852.1
ENST00000545204.1
ENST00000393413.3
ENST00000350057.5
ENST00000348801.2
ENST00000478070.1
MDM2









MDM2 oncogene, E3 ubiquitin protein ligase









chr4_-_47916543 0.074 ENST00000507489.1
NFXL1
nuclear transcription factor, X-box binding-like 1
chr15_+_69365272 0.073 ENST00000559914.1
ENST00000558369.1
LINC00277

long intergenic non-protein coding RNA 277

chr10_+_124913793 0.073 ENST00000368865.4
ENST00000538238.1
ENST00000368859.2
BUB3


BUB3 mitotic checkpoint protein


chr22_+_31489344 0.072 ENST00000404574.1
SMTN
smoothelin
chr16_-_70729496 0.072 ENST00000567648.1
VAC14
Vac14 homolog (S. cerevisiae)
chr15_+_69857515 0.071 ENST00000559477.1
RP11-279F6.1
RP11-279F6.1
chr10_-_105212059 0.071 ENST00000260743.5
CALHM2
calcium homeostasis modulator 2
chr12_+_52306113 0.069 ENST00000547400.1
ENST00000550683.1
ENST00000419526.2
ACVRL1


activin A receptor type II-like 1


chr2_-_178257401 0.068 ENST00000464747.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr19_-_58090240 0.067 ENST00000196489.3
ZNF416
zinc finger protein 416
chr19_-_5293243 0.067 ENST00000591760.1
PTPRS
protein tyrosine phosphatase, receptor type, S
chr16_+_30006615 0.066 ENST00000563197.1
INO80E
INO80 complex subunit E
chr4_-_47916613 0.066 ENST00000381538.3
ENST00000329043.3
NFXL1

nuclear transcription factor, X-box binding-like 1

chr2_-_47168906 0.065 ENST00000444761.2
ENST00000409147.1
MCFD2

multiple coagulation factor deficiency 2

chr2_+_178257372 0.065 ENST00000264167.4
ENST00000409888.1
AGPS

alkylglycerone phosphate synthase

chr2_-_112614424 0.065 ENST00000427997.1
ANAPC1
anaphase promoting complex subunit 1
chr8_-_144413981 0.064 ENST00000522041.1
TOP1MT
topoisomerase (DNA) I, mitochondrial
chr2_+_108994466 0.064 ENST00000272452.2
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr16_+_28834531 0.064 ENST00000570200.1
ATXN2L
ataxin 2-like
chrX_+_150148976 0.063 ENST00000419110.1
HMGB3
high mobility group box 3
chr17_-_40729681 0.063 ENST00000590760.1
ENST00000587209.1
ENST00000393795.3
ENST00000253789.5
PSMC3IP



PSMC3 interacting protein



chrX_-_84363974 0.063 ENST00000395409.3
ENST00000332921.5
ENST00000509231.1
SATL1


spermidine/spermine N1-acetyl transferase-like 1


chr12_-_122712038 0.062 ENST00000413918.1
ENST00000443649.3
DIABLO

diablo, IAP-binding mitochondrial protein

chr8_-_37351424 0.062 ENST00000522718.1
RP11-150O12.1
RP11-150O12.1
chr5_-_169626104 0.061 ENST00000520275.1
ENST00000506431.2
CTB-27N1.1

CTB-27N1.1

chr14_-_23904861 0.061 ENST00000355349.3
MYH7
myosin, heavy chain 7, cardiac muscle, beta
chr3_+_138066539 0.060 ENST00000289104.4
MRAS
muscle RAS oncogene homolog
chr22_+_38302285 0.060 ENST00000215957.6
MICALL1
MICAL-like 1
chr9_+_131218336 0.059 ENST00000372814.3
ODF2
outer dense fiber of sperm tails 2
chr6_+_10748019 0.058 ENST00000461342.1
ENST00000475942.1
ENST00000379530.3
ENST00000473276.1
ENST00000481240.1
ENST00000467317.1
ENST00000543878.1
TMEM14B





SYCP2L
transmembrane protein 14B





synaptonemal complex protein 2-like

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0007497 posterior midgut development(GO:0007497) positive regulation of penile erection(GO:0060406) endothelin receptor signaling pathway(GO:0086100)
0.5 3.6 GO:0071461 cellular response to redox state(GO:0071461)
0.2 0.6 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 0.6 GO:0070384 Harderian gland development(GO:0070384)
0.1 0.4 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.1 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1 0.2 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1 0.2 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 0.5 GO:0003383 apical constriction(GO:0003383)
0.1 0.3 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.2 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.2 GO:0035397 helper T cell enhancement of adaptive immune response(GO:0035397)
0.0 0.2 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.2 GO:0071898 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.0 0.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.6 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.4 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.4 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.5 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.0 0.1 GO:0006408 snRNA export from nucleus(GO:0006408)
0.0 0.1 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.2 GO:0048817 negative regulation of hair follicle maturation(GO:0048817) negative regulation of hair follicle development(GO:0051799)
0.0 0.2 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.2 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.2 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055) endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.1 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.2 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.1 GO:0071262 regulation of eIF2 alpha phosphorylation by amino acid starvation(GO:0060733) regulation of translational initiation in response to starvation(GO:0071262) positive regulation of translational initiation in response to starvation(GO:0071264)
0.0 0.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.2 GO:0060431 primary lung bud formation(GO:0060431)
0.0 0.2 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.1 GO:0006203 dGTP catabolic process(GO:0006203)
0.0 0.3 GO:0009629 response to gravity(GO:0009629)
0.0 0.3 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.1 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.0 0.4 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.3 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.0 GO:0072684 mitochondrial tRNA 3'-trailer cleavage, endonucleolytic(GO:0072684)
0.0 0.1 GO:2000834 androgen secretion(GO:0035935) testosterone secretion(GO:0035936) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.0 0.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.0 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.0 0.2 GO:1901741 positive regulation of myoblast fusion(GO:1901741)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0031523 Myb complex(GO:0031523)
0.1 0.3 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 0.4 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.2 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.0 0.3 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.2 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.4 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0044753 amphisome(GO:0044753)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 0.4 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0004962 endothelin receptor activity(GO:0004962)
0.4 3.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.6 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.9 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.2 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.6 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.0 0.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.3 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.2 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.1 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 0.1 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.1 GO:0019808 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.0 0.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.0 0.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.0 GO:0031896 vasopressin receptor binding(GO:0031893) V2 vasopressin receptor binding(GO:0031896)
0.0 0.2 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.3 GO:0043394 proteoglycan binding(GO:0043394)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.2 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 3.0 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.2 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.4 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 3.0 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.8 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors