Motif ID: TFEC_MITF_ARNTL_BHLHE41

Z-value: 1.305


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ARNTLhg19_v2_chr11_+_13299186_132994320.771.5e-02Click!
MITFhg19_v2_chr3_+_69985792_69985874-0.713.3e-02Click!
TFEChg19_v2_chr7_-_115670792_115670798-0.333.9e-01Click!
BHLHE41hg19_v2_chr12_-_26278030_26278060-0.215.8e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of TFEC_MITF_ARNTL_BHLHE41

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_4508925 3.400 ENST00000534863.1
ENST00000383843.5
ENST00000458465.2
ENST00000405420.2
ENST00000272902.5
SUMF1




sulfatase modifying factor 1




chr17_-_7137857 2.330 ENST00000005340.5
DVL2
dishevelled segment polarity protein 2
chr12_-_58145889 2.227 ENST00000547853.1
CDK4
cyclin-dependent kinase 4
chrX_+_100663243 2.209 ENST00000316594.5
HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr17_-_7137582 2.074 ENST00000575756.1
ENST00000575458.1
DVL2

dishevelled segment polarity protein 2

chr12_+_123849462 2.019 ENST00000543072.1
hsa-mir-8072
hsa-mir-8072
chr12_+_56109926 1.910 ENST00000547076.1
BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
chr12_+_56110247 1.839 ENST00000551926.1
BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
chr15_+_44084040 1.827 ENST00000249786.4
SERF2
small EDRK-rich factor 2
chr12_+_56109810 1.612 ENST00000257899.2
ENST00000548925.1
ENST00000549147.1
ENST00000550412.1
BLOC1S1


RP11-644F5.10
biogenesis of lysosomal organelles complex-1, subunit 1


Uncharacterized protein
chr2_+_176981307 1.605 ENST00000249501.4
HOXD10
homeobox D10
chr13_+_113951532 1.598 ENST00000332556.4
LAMP1
lysosomal-associated membrane protein 1
chr2_+_85981008 1.567 ENST00000306279.3
ATOH8
atonal homolog 8 (Drosophila)
chr22_-_38577782 1.559 ENST00000430886.1
ENST00000332509.3
ENST00000447598.2
ENST00000435484.1
ENST00000402064.1
ENST00000436218.1
PLA2G6





phospholipase A2, group VI (cytosolic, calcium-independent)





chr13_+_113951607 1.519 ENST00000397181.3
LAMP1
lysosomal-associated membrane protein 1
chr5_+_43603229 1.495 ENST00000344920.4
ENST00000512996.2
NNT

nicotinamide nucleotide transhydrogenase

chr17_+_62223320 1.453 ENST00000580828.1
ENST00000582965.1
SNORA76

small nucleolar RNA, H/ACA box 76

chr6_+_87865262 1.443 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292



zinc finger protein 292



chr1_-_31845914 1.396 ENST00000373713.2
FABP3
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr12_+_53400176 1.346 ENST00000551002.1
ENST00000420463.3
ENST00000416762.3
ENST00000549481.1
ENST00000552490.1
EIF4B




eukaryotic translation initiation factor 4B




chr20_-_2821271 1.330 ENST00000448755.1
ENST00000360652.2
PCED1A

PC-esterase domain containing 1A

chr7_+_106810165 1.313 ENST00000468401.1
ENST00000497535.1
ENST00000485846.1
HBP1


HMG-box transcription factor 1


chr19_+_8386371 1.288 ENST00000600659.2
RPS28
ribosomal protein S28
chr5_+_43602750 1.262 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
NNT


nicotinamide nucleotide transhydrogenase


chr8_+_103876528 1.221 ENST00000522939.1
ENST00000524007.1
KB-1507C5.2

HCG15011, isoform CRA_a; Protein LOC100996457

chr12_+_53399942 1.190 ENST00000262056.9
EIF4B
eukaryotic translation initiation factor 4B
chr1_-_154928562 1.182 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
PBXIP1




pre-B-cell leukemia homeobox interacting protein 1




chr19_-_8386238 1.166 ENST00000301457.2
NDUFA7
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
chr1_-_11865982 1.164 ENST00000418034.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr1_+_10092890 1.162 ENST00000253251.8
ENST00000377157.3
UBE4B

ubiquitination factor E4B

chr17_-_76124812 1.160 ENST00000592063.1
ENST00000589271.1
ENST00000322933.4
ENST00000589553.1
TMC6



transmembrane channel-like 6



chr17_-_6915616 1.143 ENST00000575889.1
AC027763.2
Uncharacterized protein
chr17_-_76124711 1.091 ENST00000306591.7
ENST00000590602.1
TMC6

transmembrane channel-like 6

chr1_-_11866034 1.090 ENST00000376590.3
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr20_-_2821756 1.089 ENST00000356872.3
ENST00000439542.1
PCED1A

PC-esterase domain containing 1A

chr17_+_78075361 1.082 ENST00000577106.1
ENST00000390015.3
GAA

glucosidase, alpha; acid

chr1_-_154193091 1.080 ENST00000362076.4
ENST00000350592.3
ENST00000368516.1
C1orf43


chromosome 1 open reading frame 43


chr19_-_10764509 1.069 ENST00000591501.1
ILF3-AS1
ILF3 antisense RNA 1 (head to head)
chr17_+_42422662 1.069 ENST00000593167.1
ENST00000585512.1
ENST00000591740.1
ENST00000592783.1
ENST00000587387.1
ENST00000588237.1
ENST00000589265.1
GRN






granulin






chr11_-_61560053 1.060 ENST00000537328.1
TMEM258
transmembrane protein 258
chr15_-_72668805 1.057 ENST00000268097.5
HEXA
hexosaminidase A (alpha polypeptide)
chr15_+_44084503 1.049 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
SERF2







small EDRK-rich factor 2







chr5_-_121413974 1.049 ENST00000231004.4
LOX
lysyl oxidase
chr1_-_26233423 1.044 ENST00000357865.2
STMN1
stathmin 1
chr8_-_126103969 1.043 ENST00000517845.1
KIAA0196
KIAA0196
chr8_-_126104055 1.037 ENST00000318410.7
KIAA0196
KIAA0196
chr1_-_154193009 1.021 ENST00000368518.1
ENST00000368519.1
ENST00000368521.5
C1orf43


chromosome 1 open reading frame 43


chr4_-_23891693 1.015 ENST00000264867.2
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr17_+_78075498 1.011 ENST00000302262.3
GAA
glucosidase, alpha; acid
chr19_-_15236173 1.009 ENST00000527093.1
ILVBL
ilvB (bacterial acetolactate synthase)-like
chr3_+_113465866 1.006 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATP6V1A



ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A



chr19_-_49016847 1.006 ENST00000598924.1
CTC-273B12.10
CTC-273B12.10
chr19_-_5680891 0.977 ENST00000309324.4
C19orf70
chromosome 19 open reading frame 70
chr14_-_21852119 0.972 ENST00000555943.1
SUPT16H
suppressor of Ty 16 homolog (S. cerevisiae)
chr17_+_42422629 0.964 ENST00000589536.1
ENST00000587109.1
ENST00000587518.1
GRN


granulin


chr19_-_5720248 0.957 ENST00000360614.3
LONP1
lon peptidase 1, mitochondrial
chr9_-_99801925 0.955 ENST00000538255.1
CTSV
cathepsin V
chr7_+_99746514 0.955 ENST00000341942.5
ENST00000441173.1
LAMTOR4

late endosomal/lysosomal adaptor, MAPK and MTOR activator 4

chr19_-_15236470 0.951 ENST00000533747.1
ENST00000598709.1
ENST00000534378.1
ILVBL


ilvB (bacterial acetolactate synthase)-like


chr15_-_72668185 0.942 ENST00000457859.2
ENST00000566304.1
ENST00000567159.1
ENST00000429918.2
HEXA



hexosaminidase A (alpha polypeptide)



chr5_+_122110691 0.942 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
SNX2


sorting nexin 2


chr11_+_67159416 0.940 ENST00000307980.2
ENST00000544620.1
RAD9A

RAD9 homolog A (S. pombe)

chr16_+_30960375 0.939 ENST00000318663.4
ENST00000566237.1
ENST00000562699.1
ORAI3


ORAI calcium release-activated calcium modulator 3


chr19_-_49137762 0.931 ENST00000593500.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr19_-_49137790 0.931 ENST00000599385.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr1_+_10093188 0.928 ENST00000377153.1
UBE4B
ubiquitination factor E4B
chr12_-_104359475 0.927 ENST00000553183.1
C12orf73
chromosome 12 open reading frame 73
chr16_-_88923285 0.919 ENST00000542788.1
ENST00000569433.1
ENST00000268695.5
ENST00000568311.1
GALNS



galactosamine (N-acetyl)-6-sulfate sulfatase



chr16_+_2570340 0.917 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
AMDHD2





amidohydrolase domain containing 2





chr12_-_114211474 0.916 ENST00000550905.1
ENST00000547963.1
RP11-438N16.1

RP11-438N16.1

chr1_-_156265438 0.913 ENST00000362007.1
C1orf85
chromosome 1 open reading frame 85
chr22_-_38577731 0.912 ENST00000335539.3
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr19_-_15236562 0.911 ENST00000263383.3
ILVBL
ilvB (bacterial acetolactate synthase)-like
chr19_-_5719860 0.909 ENST00000590729.1
LONP1
lon peptidase 1, mitochondrial
chr10_+_99344071 0.909 ENST00000370647.4
ENST00000370646.4
HOGA1

4-hydroxy-2-oxoglutarate aldolase 1

chr19_-_11545920 0.905 ENST00000356392.4
ENST00000591179.1
CCDC151

coiled-coil domain containing 151

chr19_-_5720123 0.905 ENST00000587365.1
ENST00000585374.1
ENST00000593119.1
LONP1


lon peptidase 1, mitochondrial


chr12_+_56110315 0.902 ENST00000548556.1
BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
chr10_-_50970382 0.901 ENST00000419399.1
ENST00000432695.1
OGDHL

oxoglutarate dehydrogenase-like

chr17_+_42422637 0.880 ENST00000053867.3
ENST00000588143.1
GRN

granulin

chr11_-_61560254 0.870 ENST00000543510.1
TMEM258
transmembrane protein 258
chr2_+_176972000 0.858 ENST00000249504.5
HOXD11
homeobox D11
chr12_-_114211444 0.853 ENST00000510694.2
ENST00000550223.1
RP11-438N16.1

RP11-438N16.1

chrX_+_102631248 0.842 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
NGFRAP1


nerve growth factor receptor (TNFRSF16) associated protein 1


chr17_-_18266660 0.832 ENST00000582653.1
ENST00000352886.6
SHMT1

serine hydroxymethyltransferase 1 (soluble)

chr8_+_26240414 0.804 ENST00000380629.2
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chrX_+_102631844 0.799 ENST00000372634.1
ENST00000299872.7
NGFRAP1

nerve growth factor receptor (TNFRSF16) associated protein 1

chr11_-_18343725 0.799 ENST00000531848.1
HPS5
Hermansky-Pudlak syndrome 5
chr8_-_126103948 0.796 ENST00000523297.1
KIAA0196
KIAA0196
chr14_-_74551096 0.794 ENST00000350259.4
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr4_-_120222076 0.788 ENST00000504110.1
C4orf3
chromosome 4 open reading frame 3
chr19_+_40854559 0.788 ENST00000598962.1
ENST00000409419.1
ENST00000409587.1
ENST00000602131.1
ENST00000409735.4
ENST00000600948.1
ENST00000356508.5
ENST00000596682.1
ENST00000594908.1
PLD3








phospholipase D family, member 3








chr16_-_30134524 0.786 ENST00000395202.1
ENST00000395199.3
ENST00000263025.4
ENST00000322266.5
ENST00000403394.1
MAPK3




mitogen-activated protein kinase 3




chr7_+_155090271 0.774 ENST00000476756.1
INSIG1
insulin induced gene 1
chr16_-_70323422 0.758 ENST00000261772.8
AARS
alanyl-tRNA synthetase
chr14_-_74551172 0.757 ENST00000553458.1
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr17_+_78075324 0.756 ENST00000570803.1
GAA
glucosidase, alpha; acid
chr12_+_112451222 0.754 ENST00000552052.1
ERP29
endoplasmic reticulum protein 29
chr11_-_2906979 0.752 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
CDKN1C




cyclin-dependent kinase inhibitor 1C (p57, Kip2)




chr10_-_93392811 0.751 ENST00000238994.5
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr19_+_49990811 0.750 ENST00000391857.4
ENST00000467825.2
RPL13A

ribosomal protein L13a

chr17_-_42200996 0.734 ENST00000587135.1
ENST00000225983.6
ENST00000393622.2
ENST00000588703.1
HDAC5



histone deacetylase 5



chr6_+_151773583 0.730 ENST00000545879.1
C6orf211
chromosome 6 open reading frame 211
chr8_+_19796381 0.717 ENST00000524029.1
ENST00000522701.1
ENST00000311322.8
LPL


lipoprotein lipase


chr10_-_105437909 0.715 ENST00000540321.1
SH3PXD2A
SH3 and PX domains 2A
chr19_+_10765003 0.715 ENST00000407004.3
ENST00000589998.1
ENST00000589600.1
ILF3


interleukin enhancer binding factor 3, 90kDa


chr17_+_57408994 0.709 ENST00000312655.4
YPEL2
yippee-like 2 (Drosophila)
chr6_-_43197189 0.700 ENST00000509253.1
ENST00000393987.2
ENST00000230431.6
DNPH1


2'-deoxynucleoside 5'-phosphate N-hydrolase 1


chr11_-_36310958 0.698 ENST00000532705.1
ENST00000263401.5
ENST00000452374.2
COMMD9


COMM domain containing 9


chrX_+_146993534 0.693 ENST00000334557.6
ENST00000439526.2
ENST00000370475.4
FMR1


fragile X mental retardation 1


chrX_+_146993449 0.692 ENST00000218200.8
ENST00000370471.3
ENST00000370477.1
FMR1


fragile X mental retardation 1


chr2_-_220083692 0.677 ENST00000265316.3
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr1_+_11866207 0.674 ENST00000312413.6
ENST00000346436.6
CLCN6

chloride channel, voltage-sensitive 6

chr4_+_78078304 0.664 ENST00000316355.5
ENST00000354403.5
ENST00000502280.1
CCNG2


cyclin G2


chr3_-_122512619 0.662 ENST00000383659.1
ENST00000306103.2
HSPBAP1

HSPB (heat shock 27kDa) associated protein 1

chr17_-_21156578 0.650 ENST00000399011.2
ENST00000468196.1
C17orf103

chromosome 17 open reading frame 103

chr14_-_93799360 0.648 ENST00000334746.5
ENST00000554565.1
ENST00000298896.3
BTBD7


BTB (POZ) domain containing 7


chr11_-_18343669 0.647 ENST00000396253.3
ENST00000349215.3
ENST00000438420.2
HPS5


Hermansky-Pudlak syndrome 5


chr16_-_30134441 0.643 ENST00000395200.1
MAPK3
mitogen-activated protein kinase 3
chr2_-_220083671 0.638 ENST00000439002.2
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr19_+_10764937 0.636 ENST00000449870.1
ENST00000318511.3
ENST00000420083.1
ILF3


interleukin enhancer binding factor 3, 90kDa


chr10_-_105452917 0.635 ENST00000427662.2
SH3PXD2A
SH3 and PX domains 2A
chr5_+_78532003 0.626 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr9_+_133454943 0.620 ENST00000319725.9
FUBP3
far upstream element (FUSE) binding protein 3
chr6_-_109703663 0.616 ENST00000368961.5
CD164
CD164 molecule, sialomucin
chr19_+_5681011 0.615 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
HSD11B1L









hydroxysteroid (11-beta) dehydrogenase 1-like









chr2_+_30370382 0.614 ENST00000402708.1
YPEL5
yippee-like 5 (Drosophila)
chr7_+_101460882 0.604 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
CUX1




cut-like homeobox 1




chr14_-_54955721 0.598 ENST00000554908.1
GMFB
glia maturation factor, beta
chr12_+_6644443 0.596 ENST00000396858.1
GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr3_-_45883558 0.595 ENST00000445698.1
ENST00000296135.6
LZTFL1

leucine zipper transcription factor-like 1

chr17_+_79935464 0.594 ENST00000581647.1
ENST00000580534.1
ENST00000579684.1
ASPSCR1


alveolar soft part sarcoma chromosome region, candidate 1


chrX_-_13835147 0.590 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr17_-_42200958 0.587 ENST00000336057.5
HDAC5
histone deacetylase 5
chr19_+_40854363 0.587 ENST00000599685.1
ENST00000392032.2
PLD3

phospholipase D family, member 3

chr19_+_14544099 0.584 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
PKN1


protein kinase N1


chr11_+_118938485 0.579 ENST00000300793.6
VPS11
vacuolar protein sorting 11 homolog (S. cerevisiae)
chr19_+_10812108 0.575 ENST00000250237.5
ENST00000592254.1
QTRT1

queuine tRNA-ribosyltransferase 1

chr5_-_175964366 0.575 ENST00000274811.4
RNF44
ring finger protein 44
chr2_+_27805971 0.572 ENST00000413371.2
ZNF512
zinc finger protein 512
chr17_+_79935418 0.572 ENST00000306729.7
ENST00000306739.4
ASPSCR1

alveolar soft part sarcoma chromosome region, candidate 1

chrX_-_13835461 0.569 ENST00000316715.4
ENST00000356942.5
GPM6B

glycoprotein M6B

chr22_+_39916558 0.560 ENST00000337304.2
ENST00000396680.1
ATF4

activating transcription factor 4

chr5_+_133706865 0.557 ENST00000265339.2
UBE2B
ubiquitin-conjugating enzyme E2B
chr8_+_26240666 0.547 ENST00000523949.1
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr5_-_14871866 0.547 ENST00000284268.6
ANKH
ANKH inorganic pyrophosphate transport regulator
chr3_-_196987309 0.545 ENST00000453607.1
DLG1
discs, large homolog 1 (Drosophila)
chrX_+_146993648 0.541 ENST00000370470.1
FMR1
fragile X mental retardation 1
chr20_+_44520009 0.537 ENST00000607482.1
ENST00000372459.2
CTSA

cathepsin A

chr1_-_26232522 0.536 ENST00000399728.1
STMN1
stathmin 1
chr9_+_34646651 0.535 ENST00000378842.3
GALT
galactose-1-phosphate uridylyltransferase
chr1_-_26232951 0.534 ENST00000426559.2
ENST00000455785.2
STMN1

stathmin 1

chr20_+_44519948 0.533 ENST00000354880.5
ENST00000191018.5
CTSA

cathepsin A

chr2_+_27805880 0.533 ENST00000379717.1
ENST00000355467.4
ENST00000556601.1
ENST00000416005.2
ZNF512



zinc finger protein 512



chr3_-_112280709 0.527 ENST00000402314.2
ENST00000283290.5
ENST00000492886.1
ATG3


autophagy related 3


chr6_+_160390102 0.525 ENST00000356956.1
IGF2R
insulin-like growth factor 2 receptor
chr19_+_1275917 0.524 ENST00000469144.1
C19orf24
chromosome 19 open reading frame 24
chrX_+_102883887 0.522 ENST00000372625.3
ENST00000372624.3
TCEAL1

transcription elongation factor A (SII)-like 1

chr6_-_99873145 0.517 ENST00000369239.5
ENST00000438806.1
PNISR

PNN-interacting serine/arginine-rich protein

chr21_+_38445539 0.514 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
TTC3





tetratricopeptide repeat domain 3





chr1_+_42922173 0.508 ENST00000455780.1
ENST00000372560.3
ENST00000372561.3
ENST00000372556.3
PPCS



phosphopantothenoylcysteine synthetase



chr15_+_75118888 0.507 ENST00000395018.4
CPLX3
complexin 3
chr20_+_57427765 0.503 ENST00000371100.4
GNAS
GNAS complex locus
chr9_-_99801592 0.503 ENST00000259470.5
CTSV
cathepsin V
chr11_-_66336060 0.503 ENST00000310325.5
CTSF
cathepsin F
chr7_-_99774945 0.503 ENST00000292377.2
GPC2
glypican 2
chr18_+_9913977 0.501 ENST00000400000.2
ENST00000340541.4
VAPA

VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa

chr10_-_50970322 0.500 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chr16_-_81129845 0.495 ENST00000569885.1
ENST00000566566.1
GCSH

glycine cleavage system protein H (aminomethyl carrier)

chr6_-_109703634 0.495 ENST00000324953.5
ENST00000310786.4
ENST00000275080.7
ENST00000413644.2
CD164



CD164 molecule, sialomucin



chr4_-_185726906 0.494 ENST00000513317.1
ACSL1
acyl-CoA synthetase long-chain family member 1
chr12_-_104350898 0.493 ENST00000552940.1
ENST00000547975.1
ENST00000549478.1
ENST00000546540.1
ENST00000546819.1
ENST00000378090.4
ENST00000547945.1
C12orf73






chromosome 12 open reading frame 73






chr1_+_33116743 0.489 ENST00000414241.3
ENST00000373493.5
RBBP4

retinoblastoma binding protein 4

chr16_-_89043377 0.487 ENST00000436887.2
ENST00000448839.1
ENST00000360302.2
CBFA2T3


core-binding factor, runt domain, alpha subunit 2; translocated to, 3


chr9_+_133320301 0.486 ENST00000352480.5
ASS1
argininosuccinate synthase 1
chr11_+_7534999 0.484 ENST00000528947.1
ENST00000299492.4
PPFIBP2

PTPRF interacting protein, binding protein 2 (liprin beta 2)

chr9_+_34646624 0.484 ENST00000450095.2
ENST00000556278.1
GALT
GALT
galactose-1-phosphate uridylyltransferase
Uncharacterized protein
chr5_+_95066823 0.483 ENST00000506817.1
ENST00000379982.3
RHOBTB3

Rho-related BTB domain containing 3

chr6_-_33385902 0.482 ENST00000374500.5
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr19_-_5340730 0.478 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
PTPRS




protein tyrosine phosphatase, receptor type, S




chr11_-_57283159 0.475 ENST00000533263.1
ENST00000278426.3
SLC43A1

solute carrier family 43 (amino acid system L transporter), member 1

chr8_-_95274536 0.472 ENST00000297596.2
ENST00000396194.2
GEM

GTP binding protein overexpressed in skeletal muscle

chr17_+_48503519 0.472 ENST00000300441.4
ENST00000541920.1
ENST00000506582.1
ENST00000504392.1
ENST00000427954.2
ACSF2




acyl-CoA synthetase family member 2




chr11_+_61560348 0.465 ENST00000574708.1
ENST00000535723.1
FADS2
FEN1
fatty acid desaturase 2
flap structure-specific endonuclease 1
chrX_+_102883620 0.464 ENST00000372626.3
TCEAL1
transcription elongation factor A (SII)-like 1
chr20_+_18118486 0.464 ENST00000432901.3
PET117
PET117 homolog (S. cerevisiae)
chr19_-_48018203 0.460 ENST00000595227.1
ENST00000593761.1
ENST00000263354.3
NAPA


N-ethylmaleimide-sensitive factor attachment protein, alpha


chr2_-_131850951 0.460 ENST00000409185.1
ENST00000389915.3
FAM168B

family with sequence similarity 168, member B

chr19_+_7587555 0.458 ENST00000601003.1
MCOLN1
mucolipin 1
chr4_-_89978299 0.458 ENST00000511976.1
ENST00000509094.1
ENST00000264344.5
ENST00000515600.1
FAM13A



family with sequence similarity 13, member A



chr1_+_42921761 0.457 ENST00000372562.1
PPCS
phosphopantothenoylcysteine synthetase
chr22_-_39636914 0.452 ENST00000381551.4
PDGFB
platelet-derived growth factor beta polypeptide
chr15_-_77197620 0.450 ENST00000565970.1
ENST00000563290.1
ENST00000565372.1
ENST00000564177.1
ENST00000568382.1
ENST00000563919.1
SCAPER





S-phase cyclin A-associated protein in the ER





chr22_-_39637135 0.449 ENST00000440375.1
PDGFB
platelet-derived growth factor beta polypeptide
chr3_-_17783990 0.448 ENST00000429383.4
ENST00000446863.1
ENST00000414349.1
ENST00000428355.1
ENST00000425944.1
ENST00000445294.1
ENST00000444471.1
ENST00000415814.2
TBC1D5







TBC1 domain family, member 5







chr21_+_44866471 0.448 ENST00000448049.1
LINC00319
long intergenic non-protein coding RNA 319
chr3_+_158519654 0.445 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
MFSD1


major facilitator superfamily domain containing 1


chr4_+_111397216 0.445 ENST00000265162.5
ENPEP
glutamyl aminopeptidase (aminopeptidase A)
chr17_+_40688190 0.440 ENST00000225927.2
NAGLU
N-acetylglucosaminidase, alpha
chr2_-_47572105 0.440 ENST00000419035.1
ENST00000448713.1
ENST00000450550.1
ENST00000413185.2
AC073283.4



AC073283.4




Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.4 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.9 2.8 GO:0043181 vacuolar sequestering(GO:0043181)
0.9 2.8 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.9 5.2 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.6 1.9 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.6 2.5 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.6 1.8 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.5 1.6 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.5 2.3 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.4 1.8 GO:1904481 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.4 2.8 GO:0006740 NADPH regeneration(GO:0006740)
0.4 1.2 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.4 1.1 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.4 6.0 GO:0060155 platelet dense granule organization(GO:0060155)
0.3 1.0 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.3 2.7 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.3 0.6 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.3 1.4 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.3 1.8 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.3 0.8 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.3 1.0 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.2 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.2 0.7 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.2 0.9 GO:0072255 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.2 1.4 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.2 1.1 GO:0043335 protein unfolding(GO:0043335)
0.2 0.9 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.2 1.9 GO:0048102 autophagic cell death(GO:0048102)
0.2 1.0 GO:0002415 immune response in mucosal-associated lymphoid tissue(GO:0002386) immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.2 0.6 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.2 0.6 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.2 1.4 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.2 0.6 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.2 0.5 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.2 1.4 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.2 0.5 GO:0006147 guanine catabolic process(GO:0006147)
0.2 0.5 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.2 0.5 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 0.9 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.2 0.6 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 1.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.4 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1 2.7 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.4 GO:1990619 histone H3-K9 deacetylation(GO:1990619)
0.1 0.5 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1 1.4 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.4 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.9 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.5 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 1.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 2.1 GO:0051450 myoblast proliferation(GO:0051450)
0.1 0.5 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.1 0.5 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.1 0.3 GO:0046356 acetyl-CoA catabolic process(GO:0046356)
0.1 0.5 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.4 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.1 0.6 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.6 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.5 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.1 0.8 GO:0034371 chylomicron remodeling(GO:0034371)
0.1 0.4 GO:0005985 sucrose metabolic process(GO:0005985)
0.1 0.4 GO:1905123 regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
0.1 0.3 GO:0034059 response to anoxia(GO:0034059)
0.1 0.4 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 0.7 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 0.4 GO:0098502 DNA dephosphorylation(GO:0098502)
0.1 1.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 0.6 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 1.0 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.4 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.7 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.1 0.8 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.1 0.2 GO:0019516 lactate oxidation(GO:0019516)
0.1 0.3 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.1 0.6 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.1 0.9 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.5 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 0.3 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.1 0.2 GO:0044209 AMP salvage(GO:0044209)
0.1 0.2 GO:0070446 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.1 0.2 GO:1902559 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.1 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.4 GO:0021546 rhombomere development(GO:0021546)
0.1 0.7 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 1.0 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.2 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.9 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.5 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.4 GO:0002005 angiotensin catabolic process in blood(GO:0002005)
0.1 1.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.2 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1 0.5 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.2 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.1 0.6 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.2 GO:2000174 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.1 1.0 GO:0015886 heme transport(GO:0015886)
0.1 0.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.2 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 1.3 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.0 0.5 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.2 GO:0032053 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.0 0.3 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.3 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.8 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.7 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.0 0.9 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.4 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 0.3 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.2 GO:1901073 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.2 GO:0008050 courtship behavior(GO:0007619) female courtship behavior(GO:0008050) negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.0 0.6 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.0 GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.0 0.1 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.0 0.2 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.0 0.2 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 1.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.1 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.2 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.2 GO:0009386 translational attenuation(GO:0009386)
0.0 0.3 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0061580 colon epithelial cell migration(GO:0061580)
0.0 1.5 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 1.1 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.0 0.2 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.2 GO:0046203 spermidine catabolic process(GO:0046203)
0.0 0.2 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.4 GO:0050942 positive regulation of pigment cell differentiation(GO:0050942)
0.0 1.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.0 0.4 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.4 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0060326 cell chemotaxis(GO:0060326)
0.0 0.6 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.1 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.0 1.1 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.2 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.0 0.5 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.3 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 3.4 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.6 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.7 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.3 GO:0051195 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.0 0.4 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) myotome development(GO:0061055)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.6 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.2 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.3 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 1.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:0001828 inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.6 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0003335 corneocyte development(GO:0003335)
0.0 0.1 GO:1901207 regulation of heart looping(GO:1901207)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.2 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664)
0.0 0.4 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.2 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0 0.2 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.3 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.5 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.6 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.1 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.7 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.3 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 1.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.4 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.1 GO:0003176 aortic valve development(GO:0003176) aortic valve morphogenesis(GO:0003180)
0.0 0.0 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.0 0.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.1 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.0 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.5 GO:0016180 snRNA processing(GO:0016180)
0.0 0.2 GO:0030818 negative regulation of cyclic nucleotide biosynthetic process(GO:0030803) negative regulation of cAMP biosynthetic process(GO:0030818)
0.0 0.0 GO:0061075 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.0 0.1 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.0 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.0 GO:0097338 response to clozapine(GO:0097338)
0.0 0.0 GO:0032077 positive regulation of deoxyribonuclease activity(GO:0032077)
0.0 0.5 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.0 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0 1.9 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.1 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0 0.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.0 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.0 GO:0045588 positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.0 0.0 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.4 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.0 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.0 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.0 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.1 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.2 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.7 GO:0001658 branching involved in ureteric bud morphogenesis(GO:0001658)
0.0 0.0 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.8 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:1902737 dendritic filopodium(GO:1902737)
0.3 3.1 GO:0044194 cytolytic granule(GO:0044194)
0.3 1.0 GO:0035101 FACT complex(GO:0035101)
0.3 1.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.3 1.0 GO:0031084 BLOC-2 complex(GO:0031084)
0.2 6.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.2 1.3 GO:0097452 GAIT complex(GO:0097452)
0.2 0.5 GO:0005960 glycine cleavage complex(GO:0005960)
0.1 0.6 GO:0033186 CAF-1 complex(GO:0033186)
0.1 1.0 GO:0071986 Ragulator complex(GO:0071986)
0.1 1.4 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.8 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.1 1.0 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 1.1 GO:0097413 Lewy body(GO:0097413)
0.1 1.6 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.5 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 1.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.9 GO:0033503 HULC complex(GO:0033503)
0.1 0.5 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 1.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.4 GO:0071817 MMXD complex(GO:0071817)
0.1 0.4 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 0.5 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 0.3 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.4 GO:1990246 uniplex complex(GO:1990246)
0.1 0.6 GO:0000125 PCAF complex(GO:0000125)
0.1 4.8 GO:0016235 aggresome(GO:0016235)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.5 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 0.4 GO:0001740 Barr body(GO:0001740)
0.1 0.6 GO:0030139 endocytic vesicle(GO:0030139)
0.1 0.3 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 0.1 GO:0019034 viral replication complex(GO:0019034)
0.1 0.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.3 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.5 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.4 GO:0070695 FHF complex(GO:0070695)
0.0 0.4 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 7.0 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.5 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.2 GO:1990742 microvesicle(GO:1990742)
0.0 0.8 GO:0042627 chylomicron(GO:0042627)
0.0 0.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.5 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 4.1 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 2.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 1.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.5 GO:0042587 glycogen granule(GO:0042587)
0.0 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0033263 CORVET complex(GO:0033263)
0.0 0.1 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0000801 central element(GO:0000801)
0.0 2.9 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.9 GO:0031143 pseudopodium(GO:0031143)
0.0 0.5 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0002133 polycystin complex(GO:0002133)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.3 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0036338 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.0 0.0 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.9 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.4 GO:0030424 axon(GO:0030424)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 0.1 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 2.4 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.0 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 1.2 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 1.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0000800 lateral element(GO:0000800)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 1.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0070820 tertiary granule(GO:0070820) ficolin-1-rich granule membrane(GO:0101003)
0.0 0.2 GO:0097227 sperm annulus(GO:0097227)
0.0 1.3 GO:0005581 collagen trimer(GO:0005581)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.0 GO:0031082 BLOC complex(GO:0031082)
0.0 0.2 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0071004 U2-type prespliceosome(GO:0071004)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.9 2.8 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.7 2.8 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.6 2.5 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.5 1.5 GO:0030984 kininogen binding(GO:0030984)
0.5 1.4 GO:0070538 oleic acid binding(GO:0070538)
0.5 2.3 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.4 1.3 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.4 1.8 GO:0070905 serine binding(GO:0070905)
0.3 4.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.3 1.9 GO:0034046 poly(G) binding(GO:0034046)
0.3 1.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.3 1.0 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.3 0.8 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.2 0.7 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.2 2.0 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.2 1.0 GO:1990460 leptin receptor binding(GO:1990460)
0.2 0.6 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 0.7 GO:0017129 triglyceride binding(GO:0017129)
0.2 0.5 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.2 0.5 GO:0033149 FFAT motif binding(GO:0033149)
0.2 0.5 GO:0008892 guanine deaminase activity(GO:0008892)
0.2 0.6 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.2 0.9 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.2 2.5 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 0.6 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 1.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 0.7 GO:0019144 ADP-sugar diphosphatase activity(GO:0019144)
0.1 1.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.4 GO:0031177 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) S-acetyltransferase activity(GO:0016418) phosphopantetheine binding(GO:0031177)
0.1 0.9 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.8 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.8 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.5 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 0.4 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.1 1.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.5 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.6 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.3 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 0.7 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.1 0.6 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.6 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 4.4 GO:0005109 frizzled binding(GO:0005109)
0.1 0.3 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.1 0.4 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 0.5 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 1.2 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.1 1.9 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.9 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.1 0.2 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.1 0.7 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.2 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.1 1.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 0.2 GO:0004458 D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898)
0.1 0.3 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.1 0.2 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.1 1.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.2 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.3 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.1 2.1 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.2 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.2 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.1 1.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.3 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.1 0.5 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.5 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 0.2 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.5 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.4 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.2 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.0 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.3 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 1.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.5 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 1.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.6 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 0.5 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.0 0.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 1.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 3.5 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.2 GO:0000403 Y-form DNA binding(GO:0000403) four-way junction helicase activity(GO:0009378)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.5 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.0 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.5 GO:0043047 single-stranded telomeric DNA binding(GO:0043047)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.6 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.9 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.3 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.2 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 5.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 1.4 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.6 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.5 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.5 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 1.4 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.0 GO:0030337 DNA polymerase processivity factor activity(GO:0030337) dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.2 GO:0016866 intramolecular transferase activity(GO:0016866)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0050610 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 2.8 GO:0005125 cytokine activity(GO:0005125)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0005542 folic acid binding(GO:0005542)
0.0 0.1 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.4 GO:0071889 14-3-3 protein binding(GO:0071889)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 4.6 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.1 1.8 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 2.0 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.9 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.7 PID_MYC_PATHWAY C-MYC pathway
0.0 0.6 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 0.4 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.0 1.3 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 1.9 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.7 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.0 1.4 PID_ATR_PATHWAY ATR signaling pathway
0.0 1.8 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.6 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.0 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.6 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 1.3 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.7 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.0 1.7 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 0.1 PID_AVB3_INTEGRIN_PATHWAY Integrins in angiogenesis
0.0 0.2 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.4 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 0.4 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.0 0.5 PID_GLYPICAN_1PATHWAY Glypican 1 network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.9 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.7 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade
0.1 2.0 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.1 5.5 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 3.1 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 3.9 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.1 2.5 REACTOME_ACYL_CHAIN_REMODELLING_OF_PE Genes involved in Acyl chain remodelling of PE
0.1 1.9 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.4 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 0.9 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.0 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 1.2 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 4.1 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.7 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 1.1 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 1.5 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.5 REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.6 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 4.5 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.6 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.6 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.4 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.8 REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.4 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.3 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.0 1.4 REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX_ Genes involved in Formation of RNA Pol II elongation complex
0.0 0.7 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.1 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 1.4 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.8 REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS Genes involved in Activation of ATR in response to replication stress
0.0 1.3 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.2 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.7 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.3 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.9 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.4 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.7 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.9 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.6 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 1.2 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 1.2 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.9 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.0 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS Genes involved in Interactions of Vpr with host cellular proteins