Motif ID: TFAP4_MSC

Z-value: 1.226

Transcription factors associated with TFAP4_MSC:

Gene SymbolEntrez IDGene Name
MSC ENSG00000178860.8 MSC
TFAP4 ENSG00000090447.7 TFAP4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TFAP4hg19_v2_chr16_-_4323015_4323076-0.909.5e-04Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of TFAP4_MSC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_178790057 3.152 ENST00000311417.2
ZMAT3
zinc finger, matrin-type 3
chr12_+_86268065 2.380 ENST00000551529.1
ENST00000256010.6
NTS

neurotensin

chr15_-_40401062 2.226 ENST00000354670.4
ENST00000559701.1
ENST00000557870.1
ENST00000558774.1
BMF



Bcl2 modifying factor



chr4_+_37892682 1.864 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1D1


TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1


chr1_-_205391178 1.790 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1



LEM domain containing 1



chr20_+_33292068 1.490 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
TP53INP2


tumor protein p53 inducible nuclear protein 2


chr12_-_68845417 1.455 ENST00000542875.1
RP11-81H14.2
RP11-81H14.2
chr3_-_178789220 1.403 ENST00000414084.1
ZMAT3
zinc finger, matrin-type 3
chr2_+_85981008 1.372 ENST00000306279.3
ATOH8
atonal homolog 8 (Drosophila)
chr11_-_66725837 1.362 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
PC



pyruvate carboxylase



chr3_+_167453493 1.281 ENST00000295777.5
ENST00000472747.2
SERPINI1

serpin peptidase inhibitor, clade I (neuroserpin), member 1

chr3_+_167453026 1.227 ENST00000472941.1
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr8_-_95961578 1.187 ENST00000448464.2
ENST00000342697.4
TP53INP1

tumor protein p53 inducible nuclear protein 1

chr11_+_66742742 1.172 ENST00000308963.4
C11orf86
chromosome 11 open reading frame 86
chr22_-_36013368 1.120 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB



myoglobin



chr9_-_34710066 1.065 ENST00000378792.1
ENST00000259607.2
CCL21

chemokine (C-C motif) ligand 21

chr8_+_81397876 0.997 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr8_+_81398444 0.978 ENST00000455036.3
ENST00000426744.2
ZBTB10

zinc finger and BTB domain containing 10

chr12_+_56473628 0.942 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
ERBB3


v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3


chr17_-_7145106 0.930 ENST00000577035.1
GABARAP
GABA(A) receptor-associated protein
chr3_+_69134124 0.913 ENST00000478935.1
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr3_-_52486841 0.865 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr4_+_78079450 0.850 ENST00000395640.1
ENST00000512918.1
CCNG2

cyclin G2

chr2_+_30370382 0.849 ENST00000402708.1
YPEL5
yippee-like 5 (Drosophila)
chr8_+_36641842 0.829 ENST00000523973.1
ENST00000399881.3
KCNU1

potassium channel, subfamily U, member 1

chr15_+_49715293 0.826 ENST00000267843.4
ENST00000560270.1
FGF7

fibroblast growth factor 7

chr17_+_39421591 0.819 ENST00000391355.1
KRTAP9-6
keratin associated protein 9-6
chrX_+_135278908 0.817 ENST00000539015.1
ENST00000370683.1
FHL1

four and a half LIM domains 1

chr5_+_102201687 0.806 ENST00000304400.7
PAM
peptidylglycine alpha-amidating monooxygenase
chr3_+_69134080 0.776 ENST00000273258.3
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr4_+_78079570 0.768 ENST00000509972.1
CCNG2
cyclin G2
chr6_+_30851840 0.768 ENST00000511510.1
ENST00000376569.3
ENST00000376575.3
ENST00000376570.4
ENST00000446312.1
ENST00000504927.1
DDR1





discoidin domain receptor tyrosine kinase 1





chr5_+_102201722 0.750 ENST00000274392.9
ENST00000455264.2
PAM

peptidylglycine alpha-amidating monooxygenase

chr5_-_58571935 0.749 ENST00000503258.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr6_+_30852130 0.745 ENST00000428153.2
ENST00000376568.3
ENST00000452441.1
ENST00000515219.1
DDR1



discoidin domain receptor tyrosine kinase 1



chr9_+_102584128 0.740 ENST00000338488.4
ENST00000395097.2
NR4A3

nuclear receptor subfamily 4, group A, member 3

chr5_+_102201509 0.733 ENST00000348126.2
ENST00000379787.4
PAM

peptidylglycine alpha-amidating monooxygenase

chr4_-_90759440 0.728 ENST00000336904.3
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr5_+_102201430 0.725 ENST00000438793.3
ENST00000346918.2
PAM

peptidylglycine alpha-amidating monooxygenase

chr8_-_37457350 0.717 ENST00000519691.1
RP11-150O12.3
RP11-150O12.3
chr11_+_7597639 0.685 ENST00000533792.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr8_-_144512576 0.676 ENST00000333480.2
MAFA
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
chrX_-_107019181 0.648 ENST00000315660.4
ENST00000372384.2
ENST00000502650.1
ENST00000506724.1
TSC22D3



TSC22 domain family, member 3



chr12_-_8815404 0.643 ENST00000359478.2
ENST00000396549.2
MFAP5

microfibrillar associated protein 5

chr2_+_233390863 0.641 ENST00000449596.1
ENST00000543200.1
CHRND

cholinergic receptor, nicotinic, delta (muscle)

chr5_+_95066823 0.636 ENST00000506817.1
ENST00000379982.3
RHOBTB3

Rho-related BTB domain containing 3

chr5_+_135364584 0.610 ENST00000442011.2
ENST00000305126.8
TGFBI

transforming growth factor, beta-induced, 68kDa

chr1_+_10271674 0.608 ENST00000377086.1
KIF1B
kinesin family member 1B
chr5_+_43603229 0.591 ENST00000344920.4
ENST00000512996.2
NNT

nicotinamide nucleotide transhydrogenase

chr8_+_98788057 0.584 ENST00000517924.1
LAPTM4B
lysosomal protein transmembrane 4 beta
chr12_-_57644952 0.582 ENST00000554578.1
ENST00000546246.2
ENST00000553489.1
ENST00000332782.2
STAC3



SH3 and cysteine rich domain 3



chr6_-_31697563 0.576 ENST00000375789.2
ENST00000416410.1
DDAH2

dimethylarginine dimethylaminohydrolase 2

chr8_+_98788003 0.573 ENST00000521545.2
LAPTM4B
lysosomal protein transmembrane 4 beta
chr8_+_81397846 0.566 ENST00000379091.4
ZBTB10
zinc finger and BTB domain containing 10
chr6_+_151042224 0.553 ENST00000358517.2
PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr1_-_150849208 0.550 ENST00000358595.5
ARNT
aryl hydrocarbon receptor nuclear translocator
chr8_-_66701319 0.549 ENST00000379419.4
PDE7A
phosphodiesterase 7A
chr15_-_52944231 0.548 ENST00000546305.2
FAM214A
family with sequence similarity 214, member A
chr18_-_19180681 0.540 ENST00000269214.5
ESCO1
establishment of sister chromatid cohesion N-acetyltransferase 1
chr16_-_31106048 0.509 ENST00000300851.6
VKORC1
vitamin K epoxide reductase complex, subunit 1
chr12_-_8815215 0.509 ENST00000544889.1
ENST00000543369.1
MFAP5

microfibrillar associated protein 5

chr4_-_140223670 0.508 ENST00000394228.1
ENST00000539387.1
NDUFC1

NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa

chr2_-_190044480 0.508 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr16_-_31106211 0.507 ENST00000319788.7
ENST00000354895.4
ENST00000394975.2
ENST00000532364.1
ENST00000529564.1
VKORC1


RP11-196G11.1

vitamin K epoxide reductase complex, subunit 1


Uncharacterized protein

chr11_+_33061543 0.499 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1


t-complex 11, testis-specific-like 1


chr17_+_41003166 0.498 ENST00000308423.2
AOC3
amine oxidase, copper containing 3
chr10_+_88428370 0.497 ENST00000372066.3
ENST00000263066.6
ENST00000372056.4
ENST00000310944.6
ENST00000361373.4
ENST00000542786.1
LDB3





LIM domain binding 3





chr15_-_32162833 0.491 ENST00000560598.1
OTUD7A
OTU domain containing 7A
chr17_-_41132088 0.487 ENST00000454303.1
ENST00000591916.1
ENST00000451885.2
PTGES3L-AARSD1
PTGES3L

PTGES3L-AARSD1 readthrough
prostaglandin E synthase 3 (cytosolic)-like

chr4_-_140477928 0.487 ENST00000274031.3
SETD7
SET domain containing (lysine methyltransferase) 7
chrX_-_138724677 0.485 ENST00000370573.4
ENST00000338585.6
ENST00000370576.4
MCF2


MCF.2 cell line derived transforming sequence


chr12_-_8814669 0.478 ENST00000535411.1
ENST00000540087.1
MFAP5

microfibrillar associated protein 5

chr17_-_21156578 0.476 ENST00000399011.2
ENST00000468196.1
C17orf103

chromosome 17 open reading frame 103

chr11_-_111783595 0.475 ENST00000528628.1
CRYAB
crystallin, alpha B
chr8_-_49834299 0.473 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr19_+_10527449 0.471 ENST00000592685.1
ENST00000380702.2
PDE4A

phosphodiesterase 4A, cAMP-specific

chr8_-_75233563 0.469 ENST00000342232.4
JPH1
junctophilin 1
chr17_+_40996590 0.452 ENST00000253799.3
ENST00000452774.2
AOC2

amine oxidase, copper containing 2 (retina-specific)

chr20_-_31124186 0.451 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chr15_-_42749711 0.446 ENST00000565611.1
ENST00000263805.4
ENST00000565948.1
ZNF106


zinc finger protein 106


chr16_-_31105870 0.446 ENST00000394971.3
VKORC1
vitamin K epoxide reductase complex, subunit 1
chr8_-_49833978 0.444 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr19_-_46285646 0.440 ENST00000458663.2
DMPK
dystrophia myotonica-protein kinase
chr3_+_32147997 0.434 ENST00000282541.5
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr19_+_1041187 0.430 ENST00000531467.1
ABCA7
ATP-binding cassette, sub-family A (ABC1), member 7
chr13_-_43566301 0.428 ENST00000398762.3
ENST00000313640.7
ENST00000313624.7
EPSTI1


epithelial stromal interaction 1 (breast)


chr1_-_150849047 0.421 ENST00000354396.2
ENST00000505755.1
ARNT

aryl hydrocarbon receptor nuclear translocator

chr19_+_1041212 0.417 ENST00000433129.1
ABCA7
ATP-binding cassette, sub-family A (ABC1), member 7
chr17_+_9548845 0.416 ENST00000570475.1
ENST00000285199.7
USP43

ubiquitin specific peptidase 43

chr12_-_8815299 0.412 ENST00000535336.1
MFAP5
microfibrillar associated protein 5
chr12_-_123752624 0.407 ENST00000542174.1
ENST00000535796.1
CDK2AP1

cyclin-dependent kinase 2 associated protein 1

chr14_-_70038032 0.404 ENST00000543986.1
CCDC177
coiled-coil domain containing 177
chr20_-_56195449 0.402 ENST00000541799.1
ZBP1
Z-DNA binding protein 1
chr10_+_88428206 0.402 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
LDB3


LIM domain binding 3


chr16_-_75150665 0.401 ENST00000300051.4
ENST00000450168.2
LDHD

lactate dehydrogenase D

chr21_-_10990830 0.401 ENST00000361285.4
ENST00000342420.5
ENST00000328758.5
TPTE


transmembrane phosphatase with tensin homology


chr17_+_6347729 0.400 ENST00000572447.1
FAM64A
family with sequence similarity 64, member A
chr10_+_18689637 0.398 ENST00000377315.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chrX_-_16887963 0.396 ENST00000380084.4
RBBP7
retinoblastoma binding protein 7
chr7_-_99869799 0.395 ENST00000436886.2
GATS
GATS, stromal antigen 3 opposite strand
chr2_-_175629164 0.393 ENST00000409323.1
ENST00000261007.5
ENST00000348749.5
CHRNA1


cholinergic receptor, nicotinic, alpha 1 (muscle)


chr1_+_78354243 0.393 ENST00000294624.8
NEXN
nexilin (F actin binding protein)
chr12_+_49297899 0.390 ENST00000552942.1
ENST00000320516.4
CCDC65

coiled-coil domain containing 65

chr5_-_173173171 0.379 ENST00000517733.1
ENST00000518902.1
CTB-43E15.3

CTB-43E15.3

chr3_+_54157480 0.378 ENST00000490478.1
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr3_+_49058444 0.377 ENST00000326925.6
ENST00000395458.2
NDUFAF3

NADH dehydrogenase (ubiquinone) complex I, assembly factor 3

chr1_-_117021430 0.376 ENST00000423907.1
ENST00000434879.1
ENST00000443219.1
RP4-655J12.4


RP4-655J12.4


chrX_+_135279179 0.372 ENST00000370676.3
FHL1
four and a half LIM domains 1
chr2_+_61244697 0.369 ENST00000401576.1
ENST00000295030.5
ENST00000414712.2
PEX13


peroxisomal biogenesis factor 13


chr2_-_175629135 0.368 ENST00000409542.1
ENST00000409219.1
CHRNA1

cholinergic receptor, nicotinic, alpha 1 (muscle)

chr4_-_140477353 0.368 ENST00000406354.1
ENST00000506866.2
SETD7

SET domain containing (lysine methyltransferase) 7

chr11_-_84028180 0.367 ENST00000280241.8
DLG2
discs, large homolog 2 (Drosophila)
chr2_-_224810070 0.364 ENST00000429915.1
ENST00000233055.4
WDFY1

WD repeat and FYVE domain containing 1

chr1_+_155051305 0.362 ENST00000368408.3
EFNA3
ephrin-A3
chr16_-_70323422 0.362 ENST00000261772.8
AARS
alanyl-tRNA synthetase
chr22_+_30792980 0.361 ENST00000403484.1
ENST00000405717.3
ENST00000402592.3
SEC14L2


SEC14-like 2 (S. cerevisiae)


chr3_+_32148106 0.360 ENST00000425459.1
ENST00000431009.1
GPD1L

glycerol-3-phosphate dehydrogenase 1-like

chr2_-_73460334 0.357 ENST00000258083.2
PRADC1
protease-associated domain containing 1
chr1_-_161168834 0.353 ENST00000367995.3
ENST00000367996.5
ADAMTS4

ADAM metallopeptidase with thrombospondin type 1 motif, 4

chr20_-_56195525 0.352 ENST00000371173.3
ENST00000395822.3
ENST00000340462.4
ENST00000343535.4
ZBP1



Z-DNA binding protein 1



chr3_-_52001448 0.351 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
PCBP4





poly(rC) binding protein 4





chr3_-_151176497 0.350 ENST00000282466.3
IGSF10
immunoglobulin superfamily, member 10
chr1_-_150849174 0.349 ENST00000515192.1
ARNT
aryl hydrocarbon receptor nuclear translocator
chr3_-_58200398 0.348 ENST00000318316.3
ENST00000460422.1
ENST00000483681.1
DNASE1L3


deoxyribonuclease I-like 3


chr8_-_123706338 0.347 ENST00000521608.1
RP11-973F15.1
long intergenic non-protein coding RNA 1151
chr1_+_153600869 0.345 ENST00000292169.1
ENST00000368696.3
ENST00000436839.1
S100A1


S100 calcium binding protein A1


chr4_-_103682145 0.338 ENST00000226578.4
MANBA
mannosidase, beta A, lysosomal
chr10_-_69991865 0.335 ENST00000373673.3
ATOH7
atonal homolog 7 (Drosophila)
chr9_-_33447584 0.335 ENST00000297991.4
AQP3
aquaporin 3 (Gill blood group)
chr17_+_6347761 0.334 ENST00000250056.8
ENST00000571373.1
ENST00000570337.2
ENST00000572595.2
ENST00000576056.1
FAM64A




family with sequence similarity 64, member A




chr6_-_16761678 0.333 ENST00000244769.4
ENST00000436367.1
ATXN1

ataxin 1

chr19_-_46285736 0.332 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
DMPK


dystrophia myotonica-protein kinase


chr19_+_18208603 0.330 ENST00000262811.6
MAST3
microtubule associated serine/threonine kinase 3
chr4_+_154178520 0.329 ENST00000433687.1
TRIM2
tripartite motif containing 2
chr4_-_140477910 0.329 ENST00000404104.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr4_-_103682071 0.325 ENST00000505239.1
MANBA
mannosidase, beta A, lysosomal
chr15_-_77197620 0.324 ENST00000565970.1
ENST00000563290.1
ENST00000565372.1
ENST00000564177.1
ENST00000568382.1
ENST00000563919.1
SCAPER





S-phase cyclin A-associated protein in the ER





chr12_+_12938541 0.322 ENST00000356591.4
APOLD1
apolipoprotein L domain containing 1
chr1_+_86889769 0.321 ENST00000370565.4
CLCA2
chloride channel accessory 2
chr14_-_53019211 0.319 ENST00000557374.1
ENST00000281741.4
TXNDC16

thioredoxin domain containing 16

chr11_+_33061336 0.315 ENST00000602733.1
TCP11L1
t-complex 11, testis-specific-like 1
chr4_-_54424366 0.314 ENST00000306888.2
LNX1
ligand of numb-protein X 1, E3 ubiquitin protein ligase
chr8_+_9413410 0.312 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
TNKS


tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase


chr2_-_176866978 0.308 ENST00000392540.2
ENST00000409660.1
ENST00000544803.1
ENST00000272748.4
KIAA1715



KIAA1715



chr4_+_86699834 0.307 ENST00000395183.2
ARHGAP24
Rho GTPase activating protein 24
chr4_+_184826418 0.302 ENST00000308497.4
ENST00000438269.1
STOX2

storkhead box 2

chr2_+_233404429 0.302 ENST00000389494.3
ENST00000389492.3
CHRNG

cholinergic receptor, nicotinic, gamma (muscle)

chr2_+_120125245 0.300 ENST00000393103.2
DBI
diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr8_-_128231299 0.299 ENST00000500112.1
CCAT1
colon cancer associated transcript 1 (non-protein coding)
chr1_-_219615984 0.299 ENST00000420762.1
RP11-95P13.1
RP11-95P13.1
chr4_-_186125077 0.294 ENST00000458385.2
ENST00000514798.1
ENST00000296775.6
KIAA1430


KIAA1430


chr8_-_74791051 0.293 ENST00000453587.2
ENST00000602969.1
ENST00000602593.1
ENST00000419880.3
ENST00000517608.1
UBE2W




ubiquitin-conjugating enzyme E2W (putative)




chr8_-_71581377 0.284 ENST00000276590.4
ENST00000522447.1
LACTB2

lactamase, beta 2

chr6_+_110012462 0.284 ENST00000441478.2
ENST00000230124.3
FIG4

FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)

chr22_+_31644388 0.282 ENST00000333611.4
ENST00000340552.4
LIMK2

LIM domain kinase 2

chr2_-_148778323 0.280 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
ORC4



origin recognition complex, subunit 4



chr3_-_49058479 0.280 ENST00000440857.1
DALRD3
DALR anticodon binding domain containing 3
chr11_-_63933504 0.280 ENST00000255681.6
MACROD1
MACRO domain containing 1
chr1_+_178482262 0.275 ENST00000367641.3
ENST00000367639.1
TEX35

testis expressed 35

chr15_-_55563072 0.273 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A


RAB27A, member RAS oncogene family


chr12_+_57522692 0.272 ENST00000554174.1
LRP1
low density lipoprotein receptor-related protein 1
chr1_-_40349106 0.269 ENST00000545233.1
ENST00000537440.1
ENST00000537223.1
ENST00000541099.1
ENST00000441669.2
ENST00000544981.1
ENST00000316891.5
ENST00000372818.1
TRIT1







tRNA isopentenyltransferase 1







chr8_+_38758845 0.264 ENST00000519640.1
PLEKHA2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr12_+_32655048 0.262 ENST00000427716.2
ENST00000266482.3
FGD4

FYVE, RhoGEF and PH domain containing 4

chrX_-_138724994 0.261 ENST00000536274.1
MCF2
MCF.2 cell line derived transforming sequence
chr2_-_154335300 0.258 ENST00000325926.3
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr22_+_19705928 0.257 ENST00000383045.3
ENST00000438754.2
SEPT5

septin 5

chr4_-_73434498 0.257 ENST00000286657.4
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr15_-_55562582 0.253 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr10_+_102790980 0.253 ENST00000393459.1
ENST00000224807.5
SFXN3

sideroflexin 3

chr15_+_63354769 0.251 ENST00000558910.1
TPM1
tropomyosin 1 (alpha)
chr5_+_68462944 0.251 ENST00000506572.1
CCNB1
cyclin B1
chr14_+_32963433 0.249 ENST00000554410.1
AKAP6
A kinase (PRKA) anchor protein 6
chr17_-_62009621 0.248 ENST00000349817.2
ENST00000392795.3
CD79B

CD79b molecule, immunoglobulin-associated beta

chr10_+_1102721 0.248 ENST00000263150.4
WDR37
WD repeat domain 37
chr1_+_150039787 0.245 ENST00000535106.1
VPS45
vacuolar protein sorting 45 homolog (S. cerevisiae)
chr17_-_57232596 0.243 ENST00000581068.1
ENST00000330137.7
SKA2

spindle and kinetochore associated complex subunit 2

chr5_+_68463043 0.240 ENST00000508407.1
ENST00000505500.1
CCNB1

cyclin B1

chr17_+_45286387 0.240 ENST00000572316.1
ENST00000354968.1
ENST00000576874.1
ENST00000536623.2
MYL4



myosin, light chain 4, alkali; atrial, embryonic



chr11_+_124932986 0.239 ENST00000407458.1
ENST00000298280.5
SLC37A2

solute carrier family 37 (glucose-6-phosphate transporter), member 2

chr8_+_38758737 0.238 ENST00000521746.1
ENST00000420274.1
PLEKHA2

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2

chr5_+_68462837 0.238 ENST00000256442.5
CCNB1
cyclin B1
chr11_+_124933191 0.237 ENST00000532000.1
ENST00000308074.4
SLC37A2

solute carrier family 37 (glucose-6-phosphate transporter), member 2

chr17_+_57233087 0.234 ENST00000578777.1
ENST00000577457.1
ENST00000582995.1
PRR11


proline rich 11


chr12_+_49297887 0.234 ENST00000266984.5
CCDC65
coiled-coil domain containing 65
chr8_+_75736761 0.233 ENST00000260113.2
PI15
peptidase inhibitor 15
chr2_-_148779106 0.233 ENST00000416719.1
ENST00000264169.2
ORC4

origin recognition complex, subunit 4

chrX_-_122756660 0.231 ENST00000441692.1
THOC2
THO complex 2
chr10_-_73611046 0.230 ENST00000394934.1
ENST00000394936.3
PSAP

prosaposin

chr14_+_24584508 0.229 ENST00000559354.1
ENST00000560459.1
ENST00000559593.1
ENST00000396941.4
ENST00000396936.1
DCAF11




DDB1 and CUL4 associated factor 11




chr15_-_55562479 0.229 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr11_-_2160180 0.228 ENST00000381406.4
IGF2
insulin-like growth factor 2 (somatomedin A)
chr14_+_23067166 0.226 ENST00000216327.6
ENST00000542041.1
ABHD4

abhydrolase domain containing 4

chr10_-_97321112 0.226 ENST00000607232.1
ENST00000371227.4
ENST00000371249.2
ENST00000371247.2
ENST00000371246.2
ENST00000393949.1
ENST00000353505.5
ENST00000347291.4
SORBS1







sorbin and SH3 domain containing 1







chr3_-_196911002 0.225 ENST00000452595.1
DLG1
discs, large homolog 1 (Drosophila)
chr22_+_30792846 0.225 ENST00000312932.9
ENST00000428195.1
SEC14L2

SEC14-like 2 (S. cerevisiae)

chr1_-_9129735 0.223 ENST00000377424.4
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr7_-_120497178 0.222 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
TSPAN12


tetraspanin 12


chr12_+_72233487 0.222 ENST00000482439.2
ENST00000550746.1
ENST00000491063.1
ENST00000319106.8
ENST00000485960.2
ENST00000393309.3
TBC1D15





TBC1 domain family, member 15





chr14_+_53019993 0.222 ENST00000542169.2
ENST00000555622.1
GPR137C

G protein-coupled receptor 137C


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.0 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.4 1.2 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.4 1.1 GO:2000547 mesangial cell-matrix adhesion(GO:0035759) regulation of dendritic cell dendrite assembly(GO:2000547)
0.3 1.4 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.3 0.9 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.3 0.8 GO:1901076 positive regulation of engulfment of apoptotic cell(GO:1901076)
0.3 0.8 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.2 0.7 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.2 0.7 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.2 0.9 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.2 1.7 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.2 0.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 0.5 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.2 1.4 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.2 0.6 GO:1904647 response to rotenone(GO:1904647)
0.1 0.7 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 1.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 1.0 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 1.5 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 0.4 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 1.6 GO:0051450 myoblast proliferation(GO:0051450)
0.1 0.8 GO:0060437 lung growth(GO:0060437) regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 1.3 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.1 0.5 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.3 GO:0051685 maintenance of ER location(GO:0051685)
0.1 1.7 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.5 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 2.2 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 0.6 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.7 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.3 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.1 0.4 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 1.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.3 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.2 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.1 0.5 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.2 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.1 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 0.3 GO:0015840 urea transport(GO:0015840)
0.1 0.6 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.4 GO:0098704 fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.1 0.2 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.6 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.3 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.1 0.4 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.1 0.2 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.0 0.4 GO:0023021 termination of signal transduction(GO:0023021)
0.0 0.4 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.3 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.3 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.3 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.3 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.3 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.8 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 1.1 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.1 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.3 GO:0060480 lung goblet cell differentiation(GO:0060480) lobar bronchus epithelium development(GO:0060481)
0.0 2.0 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.9 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.2 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.1 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.1 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.3 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0 0.7 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.1 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 1.5 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.7 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.3 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.0 GO:0006893 Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0 0.1 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.3 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.4 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0072254 response to mycophenolic acid(GO:0071505) cellular response to mycophenolic acid(GO:0071506) metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254) metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.4 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.4 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.6 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 4.0 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.1 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.0 0.3 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.1 GO:1900194 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.3 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.1 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.0 0.1 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.2 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.1 GO:0070640 calcitriol biosynthetic process from calciol(GO:0036378) vitamin D3 metabolic process(GO:0070640)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.2 GO:2000467 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.3 GO:0021554 optic nerve development(GO:0021554)
0.0 0.1 GO:0006848 pyruvate transport(GO:0006848) mitochondrial pyruvate transport(GO:0006850) pyruvate transmembrane transport(GO:1901475) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 1.2 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0051466 positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0 0.0 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.6 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.1 GO:0015747 urate transport(GO:0015747)
0.0 0.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.1 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682) positive regulation of transmission of nerve impulse(GO:0051971)
0.0 0.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.3 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.2 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.3 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 2.0 GO:0050880 regulation of blood vessel size(GO:0050880)
0.0 0.2 GO:0044597 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0 0.1 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.1 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 2.0 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.8 GO:0035036 sperm-egg recognition(GO:0035036)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:0043523 regulation of neuron apoptotic process(GO:0043523)
0.0 0.2 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.0 0.2 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 1.2 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 1.2 GO:0000045 autophagosome assembly(GO:0000045)
0.0 0.0 GO:0044335 canonical Wnt signaling pathway involved in neural crest cell differentiation(GO:0044335)
0.0 0.1 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.4 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.0 0.1 GO:0010446 response to alkaline pH(GO:0010446)
0.0 0.4 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.9 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.7 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 0.8 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 2.0 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.3 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 1.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.2 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 1.0 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.8 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.7 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 0.3 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.3 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.7 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.9 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.3 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.5 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 4.5 GO:0043204 perikaryon(GO:0043204)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 0.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.7 GO:0042629 mast cell granule(GO:0042629)
0.0 0.8 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.4 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.1 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 2.7 GO:0005776 autophagosome(GO:0005776)
0.0 0.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.5 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 2.3 GO:0043679 axon terminus(GO:0043679)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0000152 nuclear ubiquitin ligase complex(GO:0000152)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 1.9 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.1 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.3 GO:0032059 bleb(GO:0032059)
0.0 1.3 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.4 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 1.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.7 GO:1904115 axon cytoplasm(GO:1904115)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.0 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.3 1.3 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.3 1.5 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.3 0.8 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.2 1.0 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.2 0.8 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.2 0.6 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.2 0.6 GO:0008431 vitamin E binding(GO:0008431)
0.2 0.5 GO:0030226 alpha-2 macroglobulin receptor activity(GO:0016964) apolipoprotein receptor activity(GO:0030226)
0.2 0.8 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.7 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.4 GO:0004458 D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898)
0.1 0.4 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 1.7 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.4 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.1 0.7 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 2.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.8 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.6 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.9 GO:0031014 troponin T binding(GO:0031014)
0.1 0.3 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 0.6 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.5 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 1.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.1 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.6 GO:0043426 MRF binding(GO:0043426)
0.1 0.9 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.3 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.1 0.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.4 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.1 0.2 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 0.2 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.6 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.3 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.3 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.3 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 5.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.7 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 1.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.9 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.2 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 1.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 1.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.7 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0030395 lactose binding(GO:0030395)
0.0 1.0 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 2.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 2.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.4 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.1 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.0 GO:0070012 oligopeptidase activity(GO:0070012)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.0 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0031432 titin binding(GO:0031432)
0.0 0.7 GO:1990939 ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 1.0 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 2.5 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.6 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 0.7 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 1.0 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.7 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.3 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.6 PID_FAS_PATHWAY FAS (CD95) signaling pathway
0.0 0.7 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.0 PID_P53_REGULATION_PATHWAY p53 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.6 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.5 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 2.2 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.8 REACTOME_ACTIVATED_POINT_MUTANTS_OF_FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.3 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.8 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.7 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 0.8 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.8 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 3.5 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.6 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.0 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.8 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 1.4 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.5 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.2 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 0.5 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.7 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.8 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.5 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins