Motif ID: TCF21

Z-value: 0.944


Transcription factors associated with TCF21:

Gene SymbolEntrez IDGene Name
TCF21 ENSG00000118526.6 TCF21

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TCF21hg19_v2_chr6_+_134210243_134210276-0.157.0e-01Click!


Activity profile for motif TCF21.

activity profile for motif TCF21


Sorted Z-values histogram for motif TCF21

Sorted Z-values for motif TCF21



Network of associatons between targets according to the STRING database.



First level regulatory network of TCF21

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_79115503 1.150 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44


interferon-induced protein 44


chr13_-_78492955 0.893 ENST00000446573.1
EDNRB
endothelin receptor type B
chr13_-_78492927 0.868 ENST00000334286.5
EDNRB
endothelin receptor type B
chr15_-_75017711 0.630 ENST00000567032.1
ENST00000564596.1
ENST00000566503.1
ENST00000395049.4
ENST00000395048.2
ENST00000379727.3
CYP1A1





cytochrome P450, family 1, subfamily A, polypeptide 1





chr17_-_7493390 0.565 ENST00000538513.2
ENST00000570788.1
ENST00000250055.2
SOX15


SRY (sex determining region Y)-box 15


chr12_+_78224667 0.526 ENST00000549464.1
NAV3
neuron navigator 3
chr17_+_39421591 0.524 ENST00000391355.1
KRTAP9-6
keratin associated protein 9-6
chr2_+_33701707 0.516 ENST00000425210.1
ENST00000444784.1
ENST00000423159.1
RASGRP3


RAS guanyl releasing protein 3 (calcium and DAG-regulated)


chr1_-_94374946 0.506 ENST00000370238.3
GCLM
glutamate-cysteine ligase, modifier subunit
chr14_+_24099318 0.486 ENST00000432832.2
DHRS2
dehydrogenase/reductase (SDR family) member 2
chrX_+_15756382 0.476 ENST00000318636.3
CA5B
carbonic anhydrase VB, mitochondrial
chr3_+_101498074 0.440 ENST00000273347.5
ENST00000474165.1
NXPE3

neurexophilin and PC-esterase domain family, member 3

chr12_-_50677255 0.438 ENST00000551691.1
ENST00000394943.3
ENST00000341247.4
LIMA1


LIM domain and actin binding 1


chr7_+_66205712 0.421 ENST00000442563.1
ENST00000450873.2
ENST00000284957.5
ENST00000451741.2
RABGEF1


KCTD7
RAB guanine nucleotide exchange factor (GEF) 1


potassium channel tetramerization domain containing 7
chr2_-_3595547 0.404 ENST00000438485.1
RP13-512J5.1
Uncharacterized protein
chr8_-_99837856 0.401 ENST00000518165.1
ENST00000419617.2
STK3

serine/threonine kinase 3

chr5_-_16936340 0.382 ENST00000507288.1
ENST00000513610.1
MYO10

myosin X

chr12_+_69201923 0.370 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2





MDM2 oncogene, E3 ubiquitin protein ligase





chr10_-_28571015 0.369 ENST00000375719.3
ENST00000375732.1
MPP7

membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)

chr11_-_10920838 0.354 ENST00000503469.2
CTD-2003C8.2
CTD-2003C8.2
chr17_-_39538550 0.349 ENST00000394001.1
KRT34
keratin 34
chr3_+_101498269 0.349 ENST00000491511.2
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr4_-_142253761 0.335 ENST00000511213.1
RP11-362F19.1
RP11-362F19.1
chr2_+_33701286 0.330 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr1_-_8000872 0.322 ENST00000377507.3
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr2_+_219537015 0.318 ENST00000440309.1
ENST00000424080.1
STK36

serine/threonine kinase 36

chr1_+_78354175 0.314 ENST00000401035.3
ENST00000457030.1
ENST00000330010.8
NEXN


nexilin (F actin binding protein)


chr1_+_92414952 0.304 ENST00000449584.1
ENST00000427104.1
ENST00000355011.3
ENST00000448194.1
ENST00000426141.1
ENST00000450792.1
ENST00000548992.1
ENST00000552654.1
ENST00000457265.1
BRDT








bromodomain, testis-specific








chrX_+_69509927 0.301 ENST00000374403.3
KIF4A
kinesin family member 4A
chr1_+_237205476 0.299 ENST00000366574.2
RYR2
ryanodine receptor 2 (cardiac)
chr19_-_43702231 0.296 ENST00000597374.1
ENST00000599371.1
PSG4

pregnancy specific beta-1-glycoprotein 4

chr2_-_75745823 0.286 ENST00000452003.1
EVA1A
eva-1 homolog A (C. elegans)
chr21_+_30673091 0.286 ENST00000447177.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chrX_+_48432892 0.285 ENST00000376759.3
ENST00000430348.2
RBM3

RNA binding motif (RNP1, RRM) protein 3

chr4_+_186347388 0.284 ENST00000511138.1
ENST00000511581.1
C4orf47

chromosome 4 open reading frame 47

chr2_+_68384976 0.282 ENST00000263657.2
PNO1
partner of NOB1 homolog (S. cerevisiae)
chr8_-_112248400 0.282 ENST00000519506.1
ENST00000522778.1
RP11-946L20.4

RP11-946L20.4

chr1_-_31230650 0.281 ENST00000294507.3
LAPTM5
lysosomal protein transmembrane 5
chr19_+_50191921 0.280 ENST00000420022.3
ADM5
adrenomedullin 5 (putative)
chr14_+_104710541 0.279 ENST00000419115.1
C14orf144
chromosome 14 open reading frame 144
chr2_-_122494487 0.275 ENST00000451734.1
ENST00000285814.4
MKI67IP

nucleolar protein interacting with the FHA domain of MKI67

chr10_+_52499682 0.274 ENST00000185907.9
ENST00000374006.1
ASAH2B

N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2B

chr20_-_52210368 0.265 ENST00000371471.2
ZNF217
zinc finger protein 217
chr1_-_243326612 0.263 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
CEP170


centrosomal protein 170kDa


chr12_-_52585765 0.262 ENST00000313234.5
ENST00000394815.2
KRT80

keratin 80

chr13_+_41635617 0.253 ENST00000542082.1
WBP4
WW domain binding protein 4
chr2_+_101437487 0.248 ENST00000427413.1
ENST00000542504.1
NPAS2

neuronal PAS domain protein 2

chr3_-_176915215 0.248 ENST00000457928.2
ENST00000422442.1
TBL1XR1

transducin (beta)-like 1 X-linked receptor 1

chr13_-_50510622 0.246 ENST00000378195.2
SPRYD7
SPRY domain containing 7
chr17_+_71229346 0.243 ENST00000535032.2
ENST00000582793.1
C17orf80

chromosome 17 open reading frame 80

chr10_+_60094735 0.243 ENST00000373910.4
UBE2D1
ubiquitin-conjugating enzyme E2D 1
chr16_-_9030515 0.240 ENST00000535863.1
ENST00000381886.4
USP7

ubiquitin specific peptidase 7 (herpes virus-associated)

chr7_-_128415844 0.236 ENST00000249389.2
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chr2_+_219536749 0.236 ENST00000295709.3
ENST00000392106.2
ENST00000392105.3
ENST00000455724.1
STK36



serine/threonine kinase 36



chr4_-_123843597 0.236 ENST00000510735.1
ENST00000304430.5
NUDT6

nudix (nucleoside diphosphate linked moiety X)-type motif 6

chrX_-_108868390 0.235 ENST00000372101.2
KCNE1L
KCNE1-like
chr4_-_123844084 0.235 ENST00000339154.2
NUDT6
nudix (nucleoside diphosphate linked moiety X)-type motif 6
chr6_-_74161977 0.234 ENST00000370318.1
ENST00000370315.3
MB21D1

Mab-21 domain containing 1

chr4_+_169633310 0.234 ENST00000510998.1
PALLD
palladin, cytoskeletal associated protein
chr12_-_6960407 0.231 ENST00000540683.1
ENST00000229265.6
ENST00000535406.1
ENST00000422785.3
CDCA3



cell division cycle associated 3



chr17_+_6347729 0.229 ENST00000572447.1
FAM64A
family with sequence similarity 64, member A
chr11_+_58910295 0.228 ENST00000420244.1
FAM111A
family with sequence similarity 111, member A
chr18_+_56807096 0.228 ENST00000588875.1
SEC11C
SEC11 homolog C (S. cerevisiae)
chr1_+_78354297 0.227 ENST00000334785.7
NEXN
nexilin (F actin binding protein)
chr19_+_16186903 0.226 ENST00000588507.1
TPM4
tropomyosin 4
chr1_+_78354330 0.226 ENST00000440324.1
NEXN
nexilin (F actin binding protein)
chr11_+_117103441 0.226 ENST00000531287.1
ENST00000531452.1
RNF214

ring finger protein 214

chr16_-_3306587 0.223 ENST00000541159.1
ENST00000536379.1
ENST00000219596.1
ENST00000339854.4
MEFV



Mediterranean fever



chr14_-_53258180 0.220 ENST00000554230.1
GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
chr2_-_207078154 0.217 ENST00000447845.1
GPR1
G protein-coupled receptor 1
chr2_+_233562015 0.215 ENST00000427233.1
ENST00000373566.3
ENST00000373563.4
ENST00000428883.1
ENST00000456491.1
ENST00000409480.1
ENST00000421433.1
ENST00000425040.1
ENST00000430720.1
ENST00000409547.1
ENST00000423659.1
ENST00000409196.3
ENST00000409451.3
ENST00000429187.1
ENST00000440945.1
GIGYF2














GRB10 interacting GYF protein 2














chr2_+_192110199 0.213 ENST00000304164.4
MYO1B
myosin IB
chr15_+_63340647 0.213 ENST00000404484.4
TPM1
tropomyosin 1 (alpha)
chr2_-_207078086 0.211 ENST00000442134.1
GPR1
G protein-coupled receptor 1
chr8_+_33342268 0.210 ENST00000360128.6
MAK16
MAK16 homolog (S. cerevisiae)
chr8_-_19540086 0.209 ENST00000332246.6
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr8_-_19540266 0.208 ENST00000311540.4
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr5_-_142784888 0.207 ENST00000514699.1
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr2_+_149402009 0.201 ENST00000457184.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr2_-_214148921 0.201 ENST00000360083.3
AC079610.2
AC079610.2
chr18_+_55888767 0.200 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L


neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase


chr2_+_7017796 0.200 ENST00000382040.3
RSAD2
radical S-adenosyl methionine domain containing 2
chr2_-_55276320 0.197 ENST00000357376.3
RTN4
reticulon 4
chr5_-_142784101 0.196 ENST00000503201.1
ENST00000502892.1
NR3C1

nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

chr4_-_89442940 0.196 ENST00000527353.1
PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
chr2_+_113321939 0.196 ENST00000458012.2
POLR1B
polymerase (RNA) I polypeptide B, 128kDa
chrX_+_17755696 0.195 ENST00000419185.1
SCML1
sex comb on midleg-like 1 (Drosophila)
chr17_-_7991021 0.194 ENST00000319144.4
ALOX12B
arachidonate 12-lipoxygenase, 12R type
chr6_-_28891709 0.192 ENST00000377194.3
ENST00000377199.3
TRIM27

tripartite motif containing 27

chr12_-_68845165 0.192 ENST00000360485.3
ENST00000441255.2
RP11-81H14.2

RP11-81H14.2

chr11_+_117103333 0.190 ENST00000534428.1
RNF214
ring finger protein 214
chr11_+_58910201 0.190 ENST00000528737.1
FAM111A
family with sequence similarity 111, member A
chr19_+_45165545 0.189 ENST00000592472.1
ENST00000587729.1
ENST00000585657.1
ENST00000592789.1
ENST00000591979.1
CEACAM19




carcinoembryonic antigen-related cell adhesion molecule 19




chr5_+_68463043 0.189 ENST00000508407.1
ENST00000505500.1
CCNB1

cyclin B1

chr17_+_71228793 0.187 ENST00000426147.2
C17orf80
chromosome 17 open reading frame 80
chr3_-_189839467 0.187 ENST00000426003.1
LEPREL1
leprecan-like 1
chr6_+_10528560 0.185 ENST00000379597.3
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr1_+_203256898 0.184 ENST00000433008.1
RP11-134P9.3
RP11-134P9.3
chr15_+_63340734 0.181 ENST00000560959.1
TPM1
tropomyosin 1 (alpha)
chr5_-_59995921 0.178 ENST00000453022.2
ENST00000545085.1
ENST00000265036.5
DEPDC1B


DEP domain containing 1B


chr22_+_40742512 0.178 ENST00000454266.2
ENST00000342312.6
ADSL

adenylosuccinate lyase

chr14_-_91282726 0.178 ENST00000328459.6
ENST00000357056.2
TTC7B

tetratricopeptide repeat domain 7B

chr4_-_89152474 0.177 ENST00000515655.1
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr5_+_68462837 0.177 ENST00000256442.5
CCNB1
cyclin B1
chr10_+_98592009 0.177 ENST00000540664.1
ENST00000371103.3
LCOR

ligand dependent nuclear receptor corepressor

chr7_+_12726623 0.176 ENST00000439721.1
ARL4A
ADP-ribosylation factor-like 4A
chr5_+_68462944 0.176 ENST00000506572.1
CCNB1
cyclin B1
chr18_+_3247779 0.176 ENST00000578611.1
ENST00000583449.1
MYL12A

myosin, light chain 12A, regulatory, non-sarcomeric

chr17_+_11924129 0.173 ENST00000353533.5
ENST00000415385.3
MAP2K4

mitogen-activated protein kinase kinase 4

chr13_-_50510434 0.170 ENST00000361840.3
SPRYD7
SPRY domain containing 7
chr2_+_38177575 0.169 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
RMDN2



regulator of microtubule dynamics 2



chr22_-_30642728 0.168 ENST00000403987.3
LIF
leukemia inhibitory factor
chr2_+_74361599 0.168 ENST00000401851.1
MGC10955
MGC10955
chr3_+_145782358 0.167 ENST00000422482.1
AC107021.1
HCG1786590; PRO2533; Uncharacterized protein
chr16_-_5147743 0.167 ENST00000587133.1
ENST00000458008.4
ENST00000427587.4
FAM86A


family with sequence similarity 86, member A


chr19_+_16187085 0.167 ENST00000300933.4
TPM4
tropomyosin 4
chrX_+_17755563 0.165 ENST00000380045.3
ENST00000380041.3
ENST00000380043.3
ENST00000398080.1
SCML1



sex comb on midleg-like 1 (Drosophila)



chr15_+_63354769 0.165 ENST00000558910.1
TPM1
tropomyosin 1 (alpha)
chr15_+_63340775 0.162 ENST00000559281.1
ENST00000317516.7
TPM1

tropomyosin 1 (alpha)

chr6_+_116832789 0.161 ENST00000368599.3
FAM26E
family with sequence similarity 26, member E
chr1_-_150669604 0.161 ENST00000427665.1
ENST00000540514.1
GOLPH3L

golgi phosphoprotein 3-like

chr1_+_51701924 0.156 ENST00000242719.3
RNF11
ring finger protein 11
chr15_+_63340858 0.154 ENST00000560615.1
TPM1
tropomyosin 1 (alpha)
chr22_+_36044411 0.154 ENST00000409652.4
APOL6
apolipoprotein L, 6
chr10_-_12084770 0.153 ENST00000357604.5
UPF2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr10_+_94594351 0.151 ENST00000371552.4
EXOC6
exocyst complex component 6
chr22_+_31277661 0.151 ENST00000454145.1
ENST00000453621.1
ENST00000431368.1
ENST00000535268.1
OSBP2



oxysterol binding protein 2



chr5_-_179050066 0.150 ENST00000329433.6
ENST00000510411.1
HNRNPH1

heterogeneous nuclear ribonucleoprotein H1 (H)

chr1_-_206671061 0.150 ENST00000367119.1
C1orf147
chromosome 1 open reading frame 147
chr11_+_71498552 0.149 ENST00000346333.6
ENST00000359244.4
ENST00000426628.2
FAM86C1


family with sequence similarity 86, member C1


chr17_-_76732928 0.149 ENST00000589768.1
CYTH1
cytohesin 1
chr12_+_104458235 0.149 ENST00000229330.4
HCFC2
host cell factor C2
chr7_-_138720763 0.146 ENST00000275766.1
ZC3HAV1L
zinc finger CCCH-type, antiviral 1-like
chr6_-_143771799 0.146 ENST00000237283.8
ADAT2
adenosine deaminase, tRNA-specific 2
chr2_-_234763147 0.145 ENST00000411486.2
ENST00000432087.1
ENST00000441687.1
ENST00000414924.1
HJURP



Holliday junction recognition protein



chr9_+_6758024 0.145 ENST00000442236.2
KDM4C
lysine (K)-specific demethylase 4C
chr6_+_26458152 0.144 ENST00000312541.5
BTN2A1
butyrophilin, subfamily 2, member A1
chr8_+_19171128 0.143 ENST00000265807.3
SH2D4A
SH2 domain containing 4A
chr7_-_132766818 0.142 ENST00000262570.5
CHCHD3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr15_+_63340553 0.142 ENST00000334895.5
TPM1
tropomyosin 1 (alpha)
chr7_-_132766800 0.141 ENST00000542753.1
ENST00000448878.1
CHCHD3

coiled-coil-helix-coiled-coil-helix domain containing 3

chr17_+_16593539 0.140 ENST00000340621.5
ENST00000399273.1
ENST00000443444.2
ENST00000360524.8
ENST00000456009.1
CCDC144A




coiled-coil domain containing 144A




chr7_+_99102573 0.140 ENST00000394170.2
ZKSCAN5
zinc finger with KRAB and SCAN domains 5
chr9_-_99637820 0.139 ENST00000289032.8
ENST00000535338.1
ZNF782

zinc finger protein 782

chr1_+_46379254 0.138 ENST00000372008.2
MAST2
microtubule associated serine/threonine kinase 2
chr4_+_123844225 0.137 ENST00000274008.4
SPATA5
spermatogenesis associated 5
chr15_+_45028719 0.137 ENST00000560442.1
ENST00000558329.1
ENST00000561043.1
TRIM69


tripartite motif containing 69


chr2_-_27603582 0.136 ENST00000323703.6
ENST00000436006.1
ZNF513

zinc finger protein 513

chr2_+_102721023 0.136 ENST00000409589.1
ENST00000409329.1
IL1R1

interleukin 1 receptor, type I

chr7_-_148787768 0.134 ENST00000491431.1
ENST00000451334.3
ENST00000316286.9
ZNF786


zinc finger protein 786


chr20_-_45318051 0.134 ENST00000372102.3
TP53RK
TP53 regulating kinase
chr12_+_14572070 0.133 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
ATF7IP




activating transcription factor 7 interacting protein




chr9_+_6758109 0.133 ENST00000536108.1
KDM4C
lysine (K)-specific demethylase 4C
chr2_+_181845298 0.132 ENST00000410062.4
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr4_-_4543700 0.129 ENST00000505286.1
ENST00000306200.2
STX18

syntaxin 18

chr9_-_100954910 0.127 ENST00000375077.4
CORO2A
coronin, actin binding protein, 2A
chr6_-_72130472 0.126 ENST00000426635.2
LINC00472
long intergenic non-protein coding RNA 472
chr5_-_58571935 0.126 ENST00000503258.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr21_+_17791648 0.126 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
LINC00478


long intergenic non-protein coding RNA 478


chr20_+_30327063 0.124 ENST00000300403.6
ENST00000340513.4
TPX2

TPX2, microtubule-associated

chr15_+_63796779 0.124 ENST00000561442.1
ENST00000560070.1
ENST00000540797.1
ENST00000380324.3
ENST00000268049.7
ENST00000536001.1
ENST00000539772.1
USP3






ubiquitin specific peptidase 3






chr6_-_128841503 0.121 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
PTPRK







protein tyrosine phosphatase, receptor type, K







chr14_+_58666824 0.121 ENST00000254286.4
ACTR10
actin-related protein 10 homolog (S. cerevisiae)
chr15_-_42749711 0.119 ENST00000565611.1
ENST00000263805.4
ENST00000565948.1
ZNF106


zinc finger protein 106


chr3_-_168864315 0.119 ENST00000475754.1
ENST00000484519.1
MECOM

MDS1 and EVI1 complex locus

chr4_+_106816592 0.119 ENST00000379987.2
ENST00000453617.2
ENST00000427316.2
ENST00000514622.1
ENST00000305572.8
NPNT




nephronectin




chr1_+_78354243 0.118 ENST00000294624.8
NEXN
nexilin (F actin binding protein)
chr1_-_226595648 0.118 ENST00000366790.3
PARP1
poly (ADP-ribose) polymerase 1
chr17_+_71228740 0.116 ENST00000268942.8
ENST00000359042.2
C17orf80

chromosome 17 open reading frame 80

chr3_+_183948161 0.115 ENST00000426955.2
VWA5B2
von Willebrand factor A domain containing 5B2
chr3_-_33700589 0.114 ENST00000461133.3
ENST00000496954.2
CLASP2

cytoplasmic linker associated protein 2

chr12_-_105352080 0.113 ENST00000433540.1
SLC41A2
solute carrier family 41 (magnesium transporter), member 2
chr20_-_54967187 0.113 ENST00000422322.1
ENST00000371356.2
ENST00000451915.1
ENST00000347343.2
ENST00000395911.1
ENST00000395907.1
ENST00000441357.1
ENST00000456249.1
ENST00000420474.1
ENST00000395909.4
ENST00000395914.1
ENST00000312783.6
ENST00000395915.3
ENST00000395913.3
AURKA













aurora kinase A













chr10_-_51130715 0.113 ENST00000402038.3
PARG
poly (ADP-ribose) glycohydrolase
chr14_-_23288930 0.111 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
SLC7A7



solute carrier family 7 (amino acid transporter light chain, y+L system), member 7



chr2_+_56411131 0.111 ENST00000407595.2
CCDC85A
coiled-coil domain containing 85A
chr12_-_56326402 0.109 ENST00000547925.1
WIBG
within bgcn homolog (Drosophila)
chr20_-_23402028 0.109 ENST00000398425.3
ENST00000432543.2
ENST00000377026.4
NAPB


N-ethylmaleimide-sensitive factor attachment protein, beta


chr19_+_46801639 0.109 ENST00000244303.6
ENST00000339613.2
ENST00000533145.1
ENST00000472815.1
HIF3A



hypoxia inducible factor 3, alpha subunit



chr2_+_134877740 0.109 ENST00000409645.1
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr3_-_81792780 0.108 ENST00000489715.1
GBE1
glucan (1,4-alpha-), branching enzyme 1
chr4_-_153303658 0.108 ENST00000296555.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr16_-_29499154 0.108 ENST00000354563.5
RP11-231C14.4
Uncharacterized protein
chr21_-_10990888 0.108 ENST00000298232.7
TPTE
transmembrane phosphatase with tensin homology
chr3_-_33700933 0.107 ENST00000480013.1
CLASP2
cytoplasmic linker associated protein 2
chr20_-_61847586 0.106 ENST00000370339.3
YTHDF1
YTH domain family, member 1
chr3_+_179065474 0.106 ENST00000471841.1
ENST00000280653.7
MFN1

mitofusin 1

chr19_-_54850417 0.106 ENST00000291759.4
LILRA4
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
chr2_+_33701684 0.106 ENST00000442390.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr17_-_62499334 0.105 ENST00000579996.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr15_-_79103757 0.105 ENST00000388820.4
ADAMTS7
ADAM metallopeptidase with thrombospondin type 1 motif, 7
chr2_-_225811747 0.104 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr16_-_46655538 0.104 ENST00000303383.3
SHCBP1
SHC SH2-domain binding protein 1
chr21_-_38338773 0.103 ENST00000399120.1
ENST00000419461.1
HLCS

holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)

chr4_+_37892682 0.103 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1D1


TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1


chr1_-_150669500 0.102 ENST00000271732.3
GOLPH3L
golgi phosphoprotein 3-like
chr5_+_170288856 0.101 ENST00000523189.1
RANBP17
RAN binding protein 17
chr17_+_29421900 0.101 ENST00000358273.4
ENST00000356175.3
NF1

neurofibromin 1

chr15_+_57998821 0.101 ENST00000299638.3
POLR2M
polymerase (RNA) II (DNA directed) polypeptide M
chr17_+_29421987 0.101 ENST00000431387.4
NF1
neurofibromin 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0007497 posterior midgut development(GO:0007497) positive regulation of penile erection(GO:0060406) endothelin receptor signaling pathway(GO:0086100)
0.2 0.6 GO:0043449 insecticide metabolic process(GO:0017143) cellular alkene metabolic process(GO:0043449) olefin metabolic process(GO:1900673)
0.2 0.6 GO:0048627 myoblast development(GO:0048627)
0.2 0.5 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.1 0.4 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.1 0.6 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.1 1.0 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 0.5 GO:0097069 response to human chorionic gonadotropin(GO:0044752) cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.1 0.4 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1 0.1 GO:1900195 positive regulation of oocyte maturation(GO:1900195)
0.1 0.3 GO:0001207 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.1 0.3 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.1 0.3 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.2 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 0.4 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.2 GO:0051685 maintenance of ER location(GO:0051685)
0.1 0.2 GO:0097195 pilomotor reflex(GO:0097195)
0.1 0.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.2 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.1 0.3 GO:2001183 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.1 0.4 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.1 GO:0070781 response to biotin(GO:0070781)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.0 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.2 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.9 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.2 GO:0072709 cellular response to sorbitol(GO:0072709) negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.5 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 0.4 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.2 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.2 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.1 GO:0046010 positive regulation of growth rate(GO:0040010) negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322) positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) regulation of small intestine smooth muscle contraction(GO:1904347) positive regulation of small intestine smooth muscle contraction(GO:1904349) gastric mucosal blood circulation(GO:1990768) small intestine smooth muscle contraction(GO:1990770)
0.0 0.1 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.2 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.1 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0030886 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.3 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.3 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.0 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.2 GO:0060613 fat pad development(GO:0060613)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.0 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.0 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.2 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.2 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.0 GO:0072616 interleukin-18 secretion(GO:0072616)
0.0 0.5 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0042369 vitamin D catabolic process(GO:0042369)
0.0 0.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.1 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.0 0.2 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.0 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.1 GO:0021648 vestibulocochlear nerve morphogenesis(GO:0021648)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086) chromatin maintenance(GO:0070827)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.1 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.0 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.1 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 0.2 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.3 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 0.5 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 1.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485) integrin alpha8-beta1 complex(GO:0034678)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:0043203 axon hillock(GO:0043203)
0.0 0.0 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.9 GO:0045095 keratin filament(GO:0045095)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 0.7 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.5 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 0.4 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 0.5 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 0.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.3 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 0.4 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 0.2 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.5 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.2 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.4 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.0 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.1 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.1 GO:0031768 ghrelin receptor binding(GO:0031768)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.4 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 2.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.0 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 1.5 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.4 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.6 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.0 0.5 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 1.5 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME_OPSINS Genes involved in Opsins
0.0 0.6 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 1.0 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.4 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.3 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.1 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.4 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.2 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism