Motif ID: TBX15_MGA

Z-value: 1.253

Transcription factors associated with TBX15_MGA:

Gene SymbolEntrez IDGene Name
MGA ENSG00000174197.12 MGA
TBX15 ENSG00000092607.9 TBX15

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TBX15hg19_v2_chr1_-_119530428_1195305720.655.8e-02Click!
MGAhg19_v2_chr15_+_41913690_41913753-0.501.7e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of TBX15_MGA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_167453493 5.001 ENST00000295777.5
ENST00000472747.2
SERPINI1

serpin peptidase inhibitor, clade I (neuroserpin), member 1

chr3_+_167453026 4.562 ENST00000472941.1
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr4_-_186732048 3.053 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2




sorbin and SH3 domain containing 2




chr20_+_43343517 2.345 ENST00000372865.4
WISP2
WNT1 inducible signaling pathway protein 2
chr20_+_43343886 2.060 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chr20_+_43343476 2.003 ENST00000372868.2
WISP2
WNT1 inducible signaling pathway protein 2
chr12_-_8815404 1.820 ENST00000359478.2
ENST00000396549.2
MFAP5

microfibrillar associated protein 5

chr3_+_4535155 1.689 ENST00000544951.1
ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr2_+_74648848 1.634 ENST00000409791.1
ENST00000426787.1
ENST00000348227.4
WDR54


WD repeat domain 54


chr6_-_30815936 1.613 ENST00000442852.1
XXbac-BPG27H4.8
XXbac-BPG27H4.8
chr2_+_176972000 1.559 ENST00000249504.5
HOXD11
homeobox D11
chr3_+_4535025 1.536 ENST00000302640.8
ENST00000354582.6
ENST00000423119.2
ENST00000357086.4
ENST00000456211.2
ITPR1




inositol 1,4,5-trisphosphate receptor, type 1




chr9_+_102584128 1.529 ENST00000338488.4
ENST00000395097.2
NR4A3

nuclear receptor subfamily 4, group A, member 3

chr1_-_12677714 1.427 ENST00000376223.2
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr12_-_8815215 1.425 ENST00000544889.1
ENST00000543369.1
MFAP5

microfibrillar associated protein 5

chr4_+_111397216 1.389 ENST00000265162.5
ENPEP
glutamyl aminopeptidase (aminopeptidase A)
chr12_+_53400176 1.362 ENST00000551002.1
ENST00000420463.3
ENST00000416762.3
ENST00000549481.1
ENST00000552490.1
EIF4B




eukaryotic translation initiation factor 4B




chr12_-_8815477 1.285 ENST00000433590.2
MFAP5
microfibrillar associated protein 5
chrX_+_123095546 1.268 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
STAG2


stromal antigen 2


chr18_+_32073253 1.266 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
DTNA


dystrobrevin, alpha


chr14_+_75746781 1.253 ENST00000555347.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr12_+_53399942 1.239 ENST00000262056.9
EIF4B
eukaryotic translation initiation factor 4B
chrX_-_153775426 1.171 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chr12_-_8815299 1.137 ENST00000535336.1
MFAP5
microfibrillar associated protein 5
chr22_-_31688431 1.097 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1



phosphoinositide-3-kinase interacting protein 1



chr15_-_44092295 1.046 ENST00000249714.3
ENST00000299969.6
ENST00000319327.6
SERINC4


serine incorporator 4


chr5_-_34043310 1.004 ENST00000231338.7
C1QTNF3
C1q and tumor necrosis factor related protein 3
chr11_-_8285405 0.992 ENST00000335790.3
ENST00000534484.1
LMO1

LIM domain only 1 (rhombotin 1)

chr11_-_83393429 0.980 ENST00000426717.2
DLG2
discs, large homolog 2 (Drosophila)
chr7_-_138363824 0.894 ENST00000419765.3
SVOPL
SVOP-like
chrX_+_123095155 0.870 ENST00000371160.1
ENST00000435103.1
STAG2

stromal antigen 2

chr13_-_46543805 0.865 ENST00000378921.2
ZC3H13
zinc finger CCCH-type containing 13
chr11_+_107643129 0.865 ENST00000447610.1
AP001024.2
Uncharacterized protein
chrX_+_123095890 0.855 ENST00000435215.1
STAG2
stromal antigen 2
chr10_-_16563870 0.827 ENST00000298943.3
C1QL3
complement component 1, q subcomponent-like 3
chr1_-_151798546 0.795 ENST00000356728.6
RORC
RAR-related orphan receptor C
chr12_+_56473939 0.786 ENST00000450146.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chrX_+_123095860 0.784 ENST00000428941.1
STAG2
stromal antigen 2
chr11_-_84028180 0.772 ENST00000280241.8
DLG2
discs, large homolog 2 (Drosophila)
chr4_-_186732241 0.765 ENST00000421639.1
SORBS2
sorbin and SH3 domain containing 2
chr17_+_38219063 0.762 ENST00000584985.1
ENST00000264637.4
ENST00000450525.2
THRA


thyroid hormone receptor, alpha


chr14_-_45603657 0.721 ENST00000396062.3
FKBP3
FK506 binding protein 3, 25kDa
chr17_-_37557846 0.721 ENST00000394294.3
ENST00000583610.1
ENST00000264658.6
FBXL20


F-box and leucine-rich repeat protein 20


chr15_+_90319557 0.716 ENST00000341735.3
MESP2
mesoderm posterior 2 homolog (mouse)
chr11_+_7559485 0.703 ENST00000527790.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr3_-_48471454 0.685 ENST00000296440.6
ENST00000448774.2
PLXNB1

plexin B1

chr11_-_83393303 0.683 ENST00000398304.1
ENST00000420775.2
DLG2

discs, large homolog 2 (Drosophila)

chrX_+_99899180 0.680 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr12_+_52431016 0.678 ENST00000553200.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr1_+_27114418 0.676 ENST00000078527.4
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr18_-_45457478 0.674 ENST00000402690.2
ENST00000356825.4
SMAD2

SMAD family member 2

chr1_-_11907829 0.665 ENST00000376480.3
NPPA
natriuretic peptide A
chr4_-_73434498 0.635 ENST00000286657.4
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr1_-_205744205 0.633 ENST00000446390.2
RAB7L1
RAB7, member RAS oncogene family-like 1
chr2_-_157189180 0.627 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
NR4A2




nuclear receptor subfamily 4, group A, member 2




chr4_-_140222358 0.613 ENST00000505036.1
ENST00000544855.1
ENST00000539002.1
NDUFC1


NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa


chr11_-_27494309 0.599 ENST00000389858.4
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr2_-_61108449 0.599 ENST00000439412.1
ENST00000452343.1
AC010733.4

AC010733.4

chr6_+_32132360 0.588 ENST00000333845.6
ENST00000395512.1
ENST00000432129.1
EGFL8


EGF-like-domain, multiple 8


chr14_+_75746664 0.588 ENST00000557139.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr11_-_27494279 0.585 ENST00000379214.4
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr7_+_133261209 0.577 ENST00000545148.1
EXOC4
exocyst complex component 4
chr3_-_171528227 0.576 ENST00000356327.5
ENST00000342215.6
ENST00000340989.4
ENST00000351298.4
PLD1



phospholipase D1, phosphatidylcholine-specific



chr2_-_85895295 0.574 ENST00000428225.1
ENST00000519937.2
SFTPB

surfactant protein B

chr12_+_57610562 0.560 ENST00000349394.5
NXPH4
neurexophilin 4
chrX_+_135230712 0.546 ENST00000535737.1
FHL1
four and a half LIM domains 1
chr15_+_101402041 0.533 ENST00000558475.1
ENST00000558641.1
ENST00000559673.1
RP11-66B24.1


RP11-66B24.1


chr11_-_83393457 0.523 ENST00000404783.3
DLG2
discs, large homolog 2 (Drosophila)
chr3_-_197024394 0.519 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
DLG1




discs, large homolog 1 (Drosophila)




chr4_+_183065793 0.518 ENST00000512480.1
TENM3
teneurin transmembrane protein 3
chr12_-_110011288 0.513 ENST00000540016.1
ENST00000266839.5
MMAB

methylmalonic aciduria (cobalamin deficiency) cblB type

chr20_+_34680620 0.505 ENST00000430276.1
ENST00000373950.2
ENST00000452261.1
EPB41L1


erythrocyte membrane protein band 4.1-like 1


chr17_+_76311791 0.492 ENST00000586321.1
AC061992.2
AC061992.2
chr18_+_32073839 0.486 ENST00000590412.1
DTNA
dystrobrevin, alpha
chr15_+_76016293 0.484 ENST00000332145.2
ODF3L1
outer dense fiber of sperm tails 3-like 1
chr5_+_137514403 0.477 ENST00000513276.1
KIF20A
kinesin family member 20A
chr7_-_120497178 0.476 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
TSPAN12


tetraspanin 12


chrX_-_99891796 0.474 ENST00000373020.4
TSPAN6
tetraspanin 6
chr3_-_160117301 0.466 ENST00000326448.7
ENST00000498409.1
ENST00000475677.1
ENST00000478536.1
IFT80



intraflagellar transport 80 homolog (Chlamydomonas)



chr19_-_46285646 0.465 ENST00000458663.2
DMPK
dystrophia myotonica-protein kinase
chr17_-_36884451 0.458 ENST00000595377.1
AC006449.1
NS5ATP13TP1; Uncharacterized protein
chr3_-_49459878 0.452 ENST00000546031.1
ENST00000458307.2
ENST00000430521.1
AMT


aminomethyltransferase


chr3_+_142315225 0.434 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1





plastin 1





chr2_+_61108650 0.432 ENST00000295025.8
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chrX_-_134049262 0.431 ENST00000370783.3
MOSPD1
motile sperm domain containing 1
chr17_-_8066843 0.431 ENST00000404970.3
VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr1_+_28586006 0.427 ENST00000253063.3
SESN2
sestrin 2
chr9_-_73029540 0.426 ENST00000377126.2
KLF9
Kruppel-like factor 9
chr9_+_127023704 0.416 ENST00000373596.1
ENST00000425237.1
NEK6

NIMA-related kinase 6

chr8_+_75736761 0.416 ENST00000260113.2
PI15
peptidase inhibitor 15
chr19_-_10213335 0.415 ENST00000592641.1
ENST00000253109.4
ANGPTL6

angiopoietin-like 6

chr17_-_46682321 0.413 ENST00000225648.3
ENST00000484302.2
HOXB6

homeobox B6

chr11_-_125932685 0.410 ENST00000527967.1
CDON
cell adhesion associated, oncogene regulated
chr11_+_46402297 0.405 ENST00000405308.2
MDK
midkine (neurite growth-promoting factor 2)
chr15_-_77197620 0.405 ENST00000565970.1
ENST00000563290.1
ENST00000565372.1
ENST00000564177.1
ENST00000568382.1
ENST00000563919.1
SCAPER





S-phase cyclin A-associated protein in the ER





chr17_+_76356516 0.404 ENST00000592569.1
RP11-806H10.4
RP11-806H10.4
chr17_+_66287628 0.403 ENST00000581639.1
ENST00000452479.2
ARSG

arylsulfatase G

chr5_+_137514687 0.401 ENST00000394894.3
KIF20A
kinesin family member 20A
chr18_-_45457192 0.400 ENST00000586514.1
ENST00000591214.1
ENST00000589877.1
SMAD2


SMAD family member 2


chr2_+_172864490 0.399 ENST00000315796.4
METAP1D
methionyl aminopeptidase type 1D (mitochondrial)
chr1_+_38512799 0.388 ENST00000432922.1
ENST00000428151.1
RP5-884C9.2

RP5-884C9.2

chr3_+_183899770 0.387 ENST00000442686.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr20_-_50385138 0.379 ENST00000338821.5
ATP9A
ATPase, class II, type 9A
chr17_-_7590745 0.378 ENST00000514944.1
ENST00000503591.1
ENST00000455263.2
ENST00000420246.2
ENST00000445888.2
ENST00000509690.1
ENST00000604348.1
ENST00000269305.4
TP53







tumor protein p53







chr19_+_17337473 0.375 ENST00000598068.1
OCEL1
occludin/ELL domain containing 1
chr1_-_37499726 0.375 ENST00000373091.3
ENST00000373093.4
GRIK3

glutamate receptor, ionotropic, kainate 3

chrM_+_10053 0.373 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chr2_-_37544209 0.370 ENST00000234179.2
PRKD3
protein kinase D3
chrX_-_134049233 0.370 ENST00000370779.4
MOSPD1
motile sperm domain containing 1
chr19_-_46526304 0.363 ENST00000008938.4
PGLYRP1
peptidoglycan recognition protein 1
chr16_-_81110683 0.357 ENST00000565253.1
ENST00000378611.4
ENST00000299578.5
C16orf46


chromosome 16 open reading frame 46


chr2_+_85646054 0.356 ENST00000389938.2
SH2D6
SH2 domain containing 6
chr12_-_71551868 0.356 ENST00000247829.3
TSPAN8
tetraspanin 8
chr16_-_2205352 0.353 ENST00000563192.1
RP11-304L19.5
RP11-304L19.5
chr10_+_111765562 0.352 ENST00000360162.3
ADD3
adducin 3 (gamma)
chr17_-_79869340 0.348 ENST00000538936.2
PCYT2
phosphate cytidylyltransferase 2, ethanolamine
chr6_-_149806105 0.347 ENST00000389942.5
ENST00000416573.2
ENST00000542614.1
ENST00000409806.3
ZC3H12D



zinc finger CCCH-type containing 12D



chr12_-_57634475 0.347 ENST00000393825.1
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr20_+_34129770 0.346 ENST00000348547.2
ENST00000357394.4
ENST00000447986.1
ENST00000279052.6
ENST00000416206.1
ENST00000411577.1
ENST00000413587.1
ERGIC3






ERGIC and golgi 3






chr16_+_69221028 0.340 ENST00000336278.4
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr11_-_115127611 0.339 ENST00000545094.1
CADM1
cell adhesion molecule 1
chr19_-_7990991 0.332 ENST00000318978.4
CTXN1
cortexin 1
chr5_-_137514333 0.331 ENST00000411594.2
ENST00000430331.1
BRD8

bromodomain containing 8

chr2_-_25475120 0.331 ENST00000380746.4
ENST00000402667.1
DNMT3A

DNA (cytosine-5-)-methyltransferase 3 alpha

chr13_-_48575401 0.328 ENST00000433022.1
ENST00000544100.1
SUCLA2

succinate-CoA ligase, ADP-forming, beta subunit

chr13_-_48575376 0.327 ENST00000434484.1
SUCLA2
succinate-CoA ligase, ADP-forming, beta subunit
chr11_+_10772847 0.325 ENST00000524523.1
CTR9
CTR9, Paf1/RNA polymerase II complex component
chr3_+_142315294 0.324 ENST00000464320.1
PLS1
plastin 1
chr1_+_26737253 0.323 ENST00000326279.6
LIN28A
lin-28 homolog A (C. elegans)
chr12_-_71551652 0.322 ENST00000546561.1
TSPAN8
tetraspanin 8
chr16_-_1843694 0.322 ENST00000569769.1
SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chrX_-_70474377 0.321 ENST00000373978.1
ENST00000373981.1
ZMYM3

zinc finger, MYM-type 3

chr10_-_75226166 0.318 ENST00000544628.1
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr12_+_124997766 0.317 ENST00000543970.1
RP11-83B20.1
RP11-83B20.1
chr2_+_29033682 0.317 ENST00000379579.4
ENST00000334056.5
ENST00000449210.1
SPDYA


speedy/RINGO cell cycle regulator family member A


chr1_+_202995611 0.314 ENST00000367240.2
PPFIA4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr12_+_21525818 0.314 ENST00000240652.3
ENST00000542023.1
ENST00000537593.1
IAPP


islet amyloid polypeptide


chr11_-_6502534 0.307 ENST00000254584.2
ENST00000525235.1
ENST00000445086.2
ARFIP2


ADP-ribosylation factor interacting protein 2


chr11_+_126139005 0.306 ENST00000263578.5
ENST00000442061.2
ENST00000532125.1
FOXRED1


FAD-dependent oxidoreductase domain containing 1


chr13_-_52027134 0.306 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6




integrator complex subunit 6




chr5_-_146258291 0.305 ENST00000394411.4
ENST00000453001.1
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chr17_-_40428359 0.303 ENST00000293328.3
STAT5B
signal transducer and activator of transcription 5B
chr9_+_17134980 0.302 ENST00000380647.3
CNTLN
centlein, centrosomal protein
chr11_-_76155618 0.301 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr17_-_7120525 0.301 ENST00000447163.1
ENST00000399506.2
ENST00000302955.6
DLG4


discs, large homolog 4 (Drosophila)


chr11_-_6502580 0.300 ENST00000423813.2
ENST00000396777.3
ARFIP2

ADP-ribosylation factor interacting protein 2

chr13_-_48575443 0.298 ENST00000378654.3
SUCLA2
succinate-CoA ligase, ADP-forming, beta subunit
chr17_-_9929581 0.298 ENST00000437099.2
ENST00000396115.2
GAS7

growth arrest-specific 7

chr11_-_76155700 0.295 ENST00000572035.1
RP11-111M22.3
RP11-111M22.3
chr11_-_115375107 0.294 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1





cell adhesion molecule 1





chr12_-_107380846 0.293 ENST00000548101.1
ENST00000550496.1
ENST00000552029.1
MTERFD3


MTERF domain containing 3


chr16_+_2933229 0.292 ENST00000573965.1
ENST00000572006.1
FLYWCH2

FLYWCH family member 2

chr17_+_25799008 0.291 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
KSR1


kinase suppressor of ras 1


chr17_-_7120498 0.287 ENST00000485100.1
DLG4
discs, large homolog 4 (Drosophila)
chr5_-_146258205 0.286 ENST00000394413.3
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chrX_-_131623874 0.285 ENST00000436215.1
MBNL3
muscleblind-like splicing regulator 3
chr11_-_615570 0.284 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7


interferon regulatory factor 7


chr5_-_149516966 0.284 ENST00000517957.1
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr11_+_28129795 0.282 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
METTL15



methyltransferase like 15



chr21_-_27107344 0.281 ENST00000457143.2
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr3_-_49459865 0.280 ENST00000427987.1
AMT
aminomethyltransferase
chr11_-_114271139 0.279 ENST00000325636.4
C11orf71
chromosome 11 open reading frame 71
chr21_-_27107198 0.276 ENST00000400094.1
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr21_-_27107283 0.276 ENST00000284971.3
ENST00000400099.1
ATP5J

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6

chr15_-_77197781 0.275 ENST00000564590.1
SCAPER
S-phase cyclin A-associated protein in the ER
chrX_-_70473957 0.275 ENST00000373984.3
ENST00000314425.5
ENST00000373982.1
ZMYM3


zinc finger, MYM-type 3


chrX_+_46771848 0.273 ENST00000218343.4
PHF16
jade family PHD finger 3
chr20_+_44657845 0.273 ENST00000243964.3
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr2_+_219081817 0.272 ENST00000315717.5
ENST00000420104.1
ENST00000295685.10
ARPC2


actin related protein 2/3 complex, subunit 2, 34kDa


chr20_+_57464200 0.272 ENST00000604005.1
GNAS
GNAS complex locus
chr1_-_28969517 0.269 ENST00000263974.4
ENST00000373824.4
TAF12

TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa

chr5_+_122110691 0.268 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
SNX2


sorting nexin 2


chr9_+_139847347 0.268 ENST00000371632.3
LCN12
lipocalin 12
chr13_+_113548643 0.267 ENST00000375608.3
MCF2L
MCF.2 cell line derived transforming sequence-like
chr12_-_107380910 0.265 ENST00000392830.2
ENST00000240050.4
MTERFD3

MTERF domain containing 3

chr3_-_125094093 0.264 ENST00000484491.1
ENST00000492394.1
ENST00000471196.1
ENST00000468369.1
ENST00000544464.1
ENST00000485866.1
ENST00000360647.4
ZNF148






zinc finger protein 148






chr11_+_18477369 0.264 ENST00000396213.3
ENST00000280706.2
LDHAL6A

lactate dehydrogenase A-like 6A

chr17_+_7792101 0.264 ENST00000358181.4
ENST00000330494.7
CHD3

chromodomain helicase DNA binding protein 3

chr1_+_153950202 0.263 ENST00000608236.1
RP11-422P24.11
RP11-422P24.11
chr7_-_87849340 0.261 ENST00000419179.1
ENST00000265729.2
SRI

sorcin

chr17_+_4046964 0.260 ENST00000573984.1
CYB5D2
cytochrome b5 domain containing 2
chrX_-_131623982 0.257 ENST00000370844.1
MBNL3
muscleblind-like splicing regulator 3
chr14_+_51026743 0.253 ENST00000358385.6
ENST00000357032.3
ENST00000354525.4
ATL1


atlastin GTPase 1


chr5_+_68788594 0.252 ENST00000396442.2
ENST00000380766.2
OCLN

occludin

chr15_+_41062159 0.249 ENST00000344320.6
C15orf62
chromosome 15 open reading frame 62
chr8_-_109260897 0.245 ENST00000521297.1
ENST00000519030.1
ENST00000521440.1
ENST00000518345.1
ENST00000519627.1
ENST00000220849.5
EIF3E





eukaryotic translation initiation factor 3, subunit E





chr5_-_132112907 0.244 ENST00000458488.2
SEPT8
septin 8
chr2_+_201994208 0.243 ENST00000440180.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr19_-_44405941 0.242 ENST00000587128.1
RP11-15A1.3
RP11-15A1.3
chr12_-_112847108 0.239 ENST00000549847.1
RPL6
ribosomal protein L6
chr7_+_143013198 0.239 ENST00000343257.2
CLCN1
chloride channel, voltage-sensitive 1
chrX_+_46771711 0.238 ENST00000424392.1
ENST00000397189.1
PHF16

jade family PHD finger 3

chr12_-_111180644 0.237 ENST00000551676.1
ENST00000550991.1
ENST00000335007.5
ENST00000340766.5
PPP1CC



protein phosphatase 1, catalytic subunit, gamma isozyme



chrX_+_17393543 0.236 ENST00000380060.3
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr20_+_2517253 0.235 ENST00000358864.1
TMC2
transmembrane channel-like 2
chr16_+_68344877 0.233 ENST00000566657.1
ENST00000565745.1
ENST00000569571.1
ENST00000569047.3
ENST00000449359.3
PRMT7




protein arginine methyltransferase 7




chr14_+_35452169 0.233 ENST00000555557.1
SRP54
signal recognition particle 54kDa
chr2_-_207024233 0.230 ENST00000423725.1
ENST00000233190.6
NDUFS1

NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)

chr5_+_137514834 0.226 ENST00000508792.1
ENST00000504621.1
KIF20A

kinesin family member 20A

chr22_-_31688381 0.226 ENST00000487265.2
PIK3IP1
phosphoinositide-3-kinase interacting protein 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.6 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.5 3.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.5 1.5 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.4 1.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.3 1.2 GO:0061289 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.3 4.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.2 2.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.2 1.0 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.2 1.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 1.1 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.2 0.6 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.2 1.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.2 1.4 GO:0002005 angiotensin catabolic process in blood(GO:0002005)
0.2 0.5 GO:0040040 thermosensory behavior(GO:0040040)
0.2 0.8 GO:0008050 female courtship behavior(GO:0008050) negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.1 0.7 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 1.4 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.6 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1 0.5 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.6 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 1.0 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 0.4 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.7 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.7 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.4 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.6 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 5.4 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 1.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.7 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.4 GO:0097252 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.1 0.3 GO:0060981 cell migration involved in coronary angiogenesis(GO:0060981)
0.1 3.6 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 0.4 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 3.9 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.1 0.3 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.1 0.5 GO:0030421 defecation(GO:0030421)
0.1 0.3 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 0.3 GO:2000110 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) negative regulation of macrophage apoptotic process(GO:2000110)
0.1 0.4 GO:0051414 response to cortisol(GO:0051414)
0.1 0.1 GO:0003285 septum secundum development(GO:0003285)
0.1 0.4 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.4 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.1 9.7 GO:0007422 peripheral nervous system development(GO:0007422)
0.1 0.2 GO:0006106 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.1 0.2 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.1 0.3 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.4 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1 0.5 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 0.4 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.4 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.6 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.4 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.1 0.3 GO:2000035 regulation of stem cell division(GO:2000035)
0.1 0.3 GO:0048537 allantoin metabolic process(GO:0000255) positive regulation of gamma-delta T cell differentiation(GO:0045588) mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541)
0.0 0.5 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.2 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.7 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0051466 positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0 1.2 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.2 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.5 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 1.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.3 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.2 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.5 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.4 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.4 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.6 GO:0015825 L-serine transport(GO:0015825)
0.0 0.1 GO:2001190 natural killer cell tolerance induction(GO:0002519) positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.0 0.3 GO:0014028 notochord formation(GO:0014028)
0.0 1.0 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.3 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.4 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.6 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.3 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0 0.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.2 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.2 GO:0003104 positive regulation of glomerular filtration(GO:0003104)
0.0 1.6 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.3 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.2 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.1 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) positive regulation of connective tissue replacement(GO:1905205)
0.0 0.9 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.8 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.2 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:1903433 regulation of constitutive secretory pathway(GO:1903433)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.0 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.2 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.6 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.6 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.5 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.0 GO:0060694 regulation of cholesterol transporter activity(GO:0060694)
0.0 0.5 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.0 0.7 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.4 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.2 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
0.0 0.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.8 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.4 GO:2000810 regulation of bicellular tight junction assembly(GO:2000810)
0.0 0.1 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.5 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.4 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.0 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.0 GO:0021831 embryonic olfactory bulb interneuron precursor migration(GO:0021831) chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.0 0.7 GO:0002209 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.0 0.1 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.0 0.1 GO:0072134 nephrogenic mesenchyme morphogenesis(GO:0072134) allantois development(GO:1905069)
0.0 0.1 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.0 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.0 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.0 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074) positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.3 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.4 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.1 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.2 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.0 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.1 GO:0050893 sensory processing(GO:0050893)
0.0 0.0 GO:0001207 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 0.2 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.2 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.1 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.2 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.1 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.9 GO:0001658 branching involved in ureteric bud morphogenesis(GO:0001658)
0.0 0.1 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.0 GO:0051584 regulation of dopamine uptake involved in synaptic transmission(GO:0051584) regulation of catecholamine uptake involved in synaptic transmission(GO:0051940)
0.0 0.1 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.2 GO:0034776 response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.0 GO:0006624 vacuolar protein processing(GO:0006624)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.7 GO:0005955 calcineurin complex(GO:0005955)
0.2 5.7 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.2 1.8 GO:0035976 AP1 complex(GO:0035976)
0.2 1.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 1.0 GO:0031501 mannosyltransferase complex(GO:0031501)
0.1 0.4 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1 2.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.8 GO:1990357 terminal web(GO:1990357)
0.1 3.7 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.3 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.6 GO:1902560 GMP reductase complex(GO:1902560)
0.1 1.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.7 GO:0097486 multivesicular body lumen(GO:0097486)
0.1 9.7 GO:0043204 perikaryon(GO:0043204)
0.1 0.6 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.4 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.7 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.4 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.6 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 1.0 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.3 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.5 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.3 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.3 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 1.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.5 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.5 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.4 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.1 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 4.9 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0030914 STAGA complex(GO:0030914)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 1.1 GO:0005871 kinesin complex(GO:0005871)
0.0 0.1 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 7.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.0 GO:0097427 microtubule bundle(GO:0097427)
0.0 2.4 GO:0030018 Z disc(GO:0030018)
0.0 0.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.4 GO:0042383 sarcolemma(GO:0042383)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.8 GO:0005903 brush border(GO:0005903)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.7 2.6 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.4 1.3 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.3 1.0 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.2 1.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.2 1.1 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.2 0.8 GO:0038132 neuregulin binding(GO:0038132)
0.2 1.0 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.2 0.7 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.2 6.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 2.7 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 0.6 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.4 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.1 0.4 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 1.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.4 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 0.6 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 3.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 3.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.2 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
0.1 0.2 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.1 0.3 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.1 9.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.8 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.2 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.2 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.1 0.6 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.4 GO:0070728 leucine binding(GO:0070728)
0.1 0.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 1.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.1 0.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.2 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.2 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.3 GO:1990460 leptin receptor binding(GO:1990460)
0.1 1.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 5.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.3 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.3 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.3 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.6 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.5 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 2.1 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.3 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 1.1 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.1 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.6 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.2 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.2 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.6 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.5 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 0.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.0 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 1.8 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 10.7 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 5.4 PID_PLK1_PATHWAY PLK1 signaling events
0.1 2.1 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 5.5 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 1.1 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.3 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.9 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 7.3 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.3 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 0.8 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.0 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.4 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.0 1.2 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.8 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.7 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.5 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 0.3 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.0 0.6 PID_ATR_PATHWAY ATR signaling pathway
0.0 0.2 ST_STAT3_PATHWAY STAT3 Pathway
0.0 0.3 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 0.8 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.1 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.6 PID_INSULIN_PATHWAY Insulin Pathway
0.0 0.5 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.1 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.9 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.3 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 2.0 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.3 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 1.1 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.8 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 5.0 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.0 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.0 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.1 REACTOME_KINESINS Genes involved in Kinesins
0.0 1.0 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.1 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 2.6 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 0.9 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.6 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.4 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.6 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.9 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.1 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 1.2 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 0.6 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.0 0.3 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling