Motif ID: TBX1

Z-value: 0.950


Transcription factors associated with TBX1:

Gene SymbolEntrez IDGene Name
TBX1 ENSG00000184058.8 TBX1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TBX1hg19_v2_chr22_+_19744226_19744226-0.422.5e-01Click!


Activity profile for motif TBX1.

activity profile for motif TBX1


Sorted Z-values histogram for motif TBX1

Sorted Z-values for motif TBX1



Network of associatons between targets according to the STRING database.



First level regulatory network of TBX1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_183538319 2.914 ENST00000420553.1
ENST00000419402.1
NCF2

neutrophil cytosolic factor 2

chr5_+_35856951 2.816 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R



interleukin 7 receptor



chr12_-_121477039 2.574 ENST00000257570.5
OASL
2'-5'-oligoadenylate synthetase-like
chr12_-_121476959 2.572 ENST00000339275.5
OASL
2'-5'-oligoadenylate synthetase-like
chr12_-_121476750 2.462 ENST00000543677.1
OASL
2'-5'-oligoadenylate synthetase-like
chr2_+_69201705 1.840 ENST00000377938.2
GKN1
gastrokine 1
chr10_+_91061712 1.833 ENST00000371826.3
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr6_-_160166218 1.713 ENST00000537657.1
SOD2
superoxide dismutase 2, mitochondrial
chr22_-_36556821 1.427 ENST00000531095.1
ENST00000397293.2
ENST00000349314.2
APOL3


apolipoprotein L, 3


chr9_+_130911723 1.422 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2


lipocalin 2


chr11_-_63330842 1.406 ENST00000255695.1
HRASLS2
HRAS-like suppressor 2
chr9_-_32526184 1.365 ENST00000545044.1
ENST00000379868.1
DDX58

DEAD (Asp-Glu-Ala-Asp) box polypeptide 58

chr17_-_39538550 1.256 ENST00000394001.1
KRT34
keratin 34
chr3_-_58523010 1.254 ENST00000459701.2
ENST00000302819.5
ACOX2

acyl-CoA oxidase 2, branched chain

chr15_+_59908633 1.190 ENST00000559626.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr12_-_52685312 1.084 ENST00000327741.5
KRT81
keratin 81
chr1_-_89488510 1.008 ENST00000564665.1
ENST00000370481.4
GBP3

guanylate binding protein 3

chr5_-_138861926 0.991 ENST00000510817.1
TMEM173
transmembrane protein 173
chr9_+_214842 0.938 ENST00000453981.1
ENST00000432829.2
DOCK8

dedicator of cytokinesis 8

chr15_+_89181974 0.935 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr12_-_10321754 0.925 ENST00000539518.1
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
chr5_-_138862326 0.891 ENST00000330794.4
TMEM173
transmembrane protein 173
chr4_+_75174204 0.801 ENST00000332112.4
ENST00000514968.1
ENST00000503098.1
ENST00000502358.1
ENST00000509145.1
ENST00000505212.1
EPGN





epithelial mitogen





chr14_-_100841670 0.780 ENST00000557297.1
ENST00000555813.1
ENST00000557135.1
ENST00000556698.1
ENST00000554509.1
ENST00000555410.1
WARS





tryptophanyl-tRNA synthetase





chr9_-_110251836 0.765 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr4_+_75174180 0.764 ENST00000413830.1
EPGN
epithelial mitogen
chr3_-_66551351 0.745 ENST00000273261.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr16_+_3115298 0.743 ENST00000325568.5
ENST00000534507.1
IL32

interleukin 32

chr19_+_36195429 0.732 ENST00000392197.2
ZBTB32
zinc finger and BTB domain containing 32
chr19_+_56915668 0.729 ENST00000333201.9
ENST00000391778.3
ZNF583

zinc finger protein 583

chr2_-_75796837 0.729 ENST00000233712.1
EVA1A
eva-1 homolog A (C. elegans)
chr11_+_71846764 0.728 ENST00000456237.1
ENST00000442948.2
ENST00000546166.1
FOLR3


folate receptor 3 (gamma)


chr3_-_66551397 0.725 ENST00000383703.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr22_+_44761431 0.694 ENST00000406912.1
RP1-32I10.10
Uncharacterized protein
chr12_-_15104040 0.651 ENST00000541644.1
ENST00000545895.1
ARHGDIB

Rho GDP dissociation inhibitor (GDI) beta

chr17_-_8021710 0.641 ENST00000380149.1
ENST00000448843.2
ALOXE3

arachidonate lipoxygenase 3

chr12_+_75874984 0.629 ENST00000550491.1
GLIPR1
GLI pathogenesis-related 1
chr4_+_79475019 0.626 ENST00000508214.1
ANXA3
annexin A3
chr13_+_76378357 0.608 ENST00000489941.2
ENST00000525373.1
LMO7

LIM domain 7

chr19_+_16254488 0.602 ENST00000588246.1
ENST00000593031.1
HSH2D

hematopoietic SH2 domain containing

chr1_-_205290865 0.595 ENST00000367157.3
NUAK2
NUAK family, SNF1-like kinase, 2
chr11_+_60614946 0.589 ENST00000545580.1
CCDC86
coiled-coil domain containing 86
chr12_-_121454148 0.587 ENST00000535367.1
ENST00000538296.1
ENST00000445832.3
ENST00000536407.2
ENST00000366211.2
ENST00000539736.1
ENST00000288757.3
ENST00000537817.1
C12orf43







chromosome 12 open reading frame 43







chr13_+_76378305 0.586 ENST00000526371.1
ENST00000526528.1
LMO7

LIM domain 7

chr1_+_66797687 0.553 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
PDE4B


phosphodiesterase 4B, cAMP-specific


chr10_-_92681033 0.525 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr6_-_86099898 0.517 ENST00000455071.1
RP11-30P6.6
RP11-30P6.6
chr4_+_160188889 0.517 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr7_-_752577 0.516 ENST00000544935.1
ENST00000430040.1
ENST00000456696.2
ENST00000406797.1
PRKAR1B



protein kinase, cAMP-dependent, regulatory, type I, beta



chr19_-_49362621 0.516 ENST00000594195.1
ENST00000595867.1
PLEKHA4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

chr1_-_94079648 0.505 ENST00000370247.3
BCAR3
breast cancer anti-estrogen resistance 3
chr5_+_150040403 0.501 ENST00000517768.1
ENST00000297130.4
MYOZ3

myozenin 3

chr1_-_153538011 0.501 ENST00000368707.4
S100A2
S100 calcium binding protein A2
chr22_+_50981079 0.498 ENST00000609268.1
CTA-384D8.34
CTA-384D8.34
chr12_+_104324112 0.496 ENST00000299767.5
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr2_+_228736321 0.481 ENST00000309931.2
DAW1
dynein assembly factor with WDR repeat domains 1
chr15_-_73075964 0.481 ENST00000563907.1
ADPGK
ADP-dependent glucokinase
chr11_+_86511549 0.475 ENST00000533902.2
PRSS23
protease, serine, 23
chr3_+_40547483 0.471 ENST00000420891.1
ENST00000314529.6
ENST00000418905.1
ZNF620


zinc finger protein 620


chr15_+_69591235 0.471 ENST00000395407.2
ENST00000558684.1
PAQR5

progestin and adipoQ receptor family member V

chr9_-_123676827 0.458 ENST00000546084.1
TRAF1
TNF receptor-associated factor 1
chrX_-_70329118 0.453 ENST00000374188.3
IL2RG
interleukin 2 receptor, gamma
chr12_-_15114191 0.433 ENST00000541380.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr3_+_159570722 0.424 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr19_+_10381769 0.422 ENST00000423829.2
ENST00000588645.1
ICAM1

intercellular adhesion molecule 1

chr2_-_207078086 0.419 ENST00000442134.1
GPR1
G protein-coupled receptor 1
chrX_+_1387721 0.419 ENST00000419094.1
ENST00000381509.3
ENST00000494969.2
ENST00000355805.2
ENST00000355432.3
CSF2RA




colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)




chr3_+_171844762 0.415 ENST00000443501.1
FNDC3B
fibronectin type III domain containing 3B
chrX_+_1387693 0.414 ENST00000381529.3
ENST00000432318.2
ENST00000361536.3
ENST00000501036.2
ENST00000381524.3
ENST00000412290.1
CSF2RA





colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)





chr17_-_29641104 0.414 ENST00000577894.1
ENST00000330927.4
EVI2B

ecotropic viral integration site 2B

chr1_+_183441618 0.410 ENST00000507691.2
ENST00000508461.1
ENST00000419169.1
ENST00000347615.2
ENST00000507469.1
ENST00000515829.2
SMG7





SMG7 nonsense mediated mRNA decay factor





chr11_-_119599794 0.409 ENST00000264025.3
PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr14_-_23398565 0.408 ENST00000397440.4
ENST00000538452.1
ENST00000421938.2
ENST00000554867.1
ENST00000556616.1
ENST00000216350.8
ENST00000553550.1
ENST00000397441.2
ENST00000553897.1
PRMT5








protein arginine methyltransferase 5








chr1_+_28285973 0.406 ENST00000373884.5
XKR8
XK, Kell blood group complex subunit-related family, member 8
chr20_-_4055812 0.400 ENST00000379526.1
RP11-352D3.2
Uncharacterized protein
chr12_-_25801478 0.400 ENST00000540106.1
ENST00000445693.1
ENST00000545543.1
ENST00000542224.1
IFLTD1



intermediate filament tail domain containing 1



chr2_+_102972363 0.399 ENST00000409599.1
IL18R1
interleukin 18 receptor 1
chr7_+_73245193 0.399 ENST00000340958.2
CLDN4
claudin 4
chr1_+_100810575 0.398 ENST00000542213.1
CDC14A
cell division cycle 14A
chr9_+_5510558 0.396 ENST00000397747.3
PDCD1LG2
programmed cell death 1 ligand 2
chr17_-_1619491 0.393 ENST00000570416.1
ENST00000575626.1
ENST00000610106.1
ENST00000608198.1
ENST00000609442.1
ENST00000334146.3
ENST00000576489.1
ENST00000608245.1
ENST00000609398.1
ENST00000608913.1
ENST00000574016.1
ENST00000571091.1
ENST00000573127.1
ENST00000609990.1
ENST00000576749.1
MIR22HG














MIR22 host gene (non-protein coding)














chr9_+_140119618 0.392 ENST00000359069.2
C9orf169
chromosome 9 open reading frame 169
chr16_+_66429358 0.391 ENST00000539168.1
CDH5
cadherin 5, type 2 (vascular endothelium)
chr11_+_86511569 0.386 ENST00000441050.1
PRSS23
protease, serine, 23
chr2_-_207078154 0.374 ENST00000447845.1
GPR1
G protein-coupled receptor 1
chr11_+_7506713 0.368 ENST00000329293.3
ENST00000534244.1
OLFML1

olfactomedin-like 1

chr22_-_29138386 0.366 ENST00000544772.1
CHEK2
checkpoint kinase 2
chr19_-_36822551 0.366 ENST00000591372.1
LINC00665
long intergenic non-protein coding RNA 665
chr16_-_69418649 0.365 ENST00000566257.1
TERF2
telomeric repeat binding factor 2
chr11_+_7506837 0.364 ENST00000528758.1
OLFML1
olfactomedin-like 1
chr11_+_86502085 0.362 ENST00000527521.1
PRSS23
protease, serine, 23
chr7_-_105319536 0.359 ENST00000477775.1
ATXN7L1
ataxin 7-like 1
chr6_+_83073334 0.359 ENST00000369750.3
TPBG
trophoblast glycoprotein
chr17_-_1619535 0.359 ENST00000573075.1
ENST00000574306.1
MIR22HG

MIR22 host gene (non-protein coding)

chr6_+_83072923 0.357 ENST00000535040.1
TPBG
trophoblast glycoprotein
chr10_+_98592674 0.357 ENST00000356016.3
ENST00000371097.4
LCOR

ligand dependent nuclear receptor corepressor

chr8_+_144766617 0.357 ENST00000454097.1
ENST00000534303.1
ENST00000529833.1
ENST00000530574.1
ENST00000442058.2
ENST00000358656.4
ENST00000526970.1
ENST00000532158.1
ZNF707







zinc finger protein 707







chr7_-_149158187 0.356 ENST00000247930.4
ZNF777
zinc finger protein 777
chr16_-_75282088 0.354 ENST00000542031.2
BCAR1
breast cancer anti-estrogen resistance 1
chr14_-_65569244 0.350 ENST00000557277.1
ENST00000556892.1
MAX

MYC associated factor X

chr1_+_233765353 0.350 ENST00000366620.1
KCNK1
potassium channel, subfamily K, member 1
chr11_+_58938903 0.349 ENST00000532982.1
DTX4
deltex homolog 4 (Drosophila)
chr18_-_56296182 0.344 ENST00000361673.3
ALPK2
alpha-kinase 2
chr6_-_25042390 0.340 ENST00000606385.1
RP11-367G6.3
RP11-367G6.3
chr8_+_120220561 0.340 ENST00000276681.6
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr7_-_139763521 0.339 ENST00000263549.3
PARP12
poly (ADP-ribose) polymerase family, member 12
chr6_+_83073952 0.338 ENST00000543496.1
TPBG
trophoblast glycoprotein
chr11_+_7506584 0.337 ENST00000530135.1
OLFML1
olfactomedin-like 1
chr2_+_75061108 0.336 ENST00000290573.2
HK2
hexokinase 2
chr12_+_75874580 0.334 ENST00000456650.3
GLIPR1
GLI pathogenesis-related 1
chr3_+_50211240 0.333 ENST00000420831.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr7_+_76109827 0.327 ENST00000446820.2
DTX2
deltex homolog 2 (Drosophila)
chr10_+_54074033 0.325 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chr1_+_223900034 0.324 ENST00000295006.5
CAPN2
calpain 2, (m/II) large subunit
chr10_+_47746929 0.317 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
ANXA8L2



AL603965.1
annexin A8-like 2



Protein LOC100996760
chr16_-_58718638 0.315 ENST00000562397.1
ENST00000564010.1
ENST00000570214.1
ENST00000563196.1
SLC38A7



solute carrier family 38, member 7



chrX_+_37639302 0.315 ENST00000545017.1
ENST00000536160.1
CYBB

cytochrome b-245, beta polypeptide

chr5_+_154092396 0.315 ENST00000336314.4
LARP1
La ribonucleoprotein domain family, member 1
chr16_+_29840929 0.314 ENST00000566252.1
MVP
major vault protein
chr1_+_182758900 0.313 ENST00000367555.1
ENST00000367554.3
NPL

N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)

chr1_-_31902614 0.313 ENST00000596131.1
AC114494.1
HCG1787699; Uncharacterized protein
chr17_+_46184911 0.310 ENST00000580219.1
ENST00000452859.2
ENST00000393405.2
ENST00000439357.2
ENST00000359238.2
SNX11




sorting nexin 11




chr7_-_72972319 0.307 ENST00000223368.2
BCL7B
B-cell CLL/lymphoma 7B
chr19_-_344786 0.306 ENST00000264819.4
MIER2
mesoderm induction early response 1, family member 2
chr14_-_23446900 0.305 ENST00000556731.1
AJUBA
ajuba LIM protein
chr19_+_46732988 0.302 ENST00000437936.1
IGFL1
IGF-like family member 1
chr1_+_160175117 0.301 ENST00000360472.4
PEA15
phosphoprotein enriched in astrocytes 15
chr11_-_17035943 0.300 ENST00000355661.3
ENST00000532079.1
ENST00000448080.2
ENST00000531066.1
PLEKHA7



pleckstrin homology domain containing, family A member 7



chr2_-_220118631 0.300 ENST00000248437.4
TUBA4A
tubulin, alpha 4a
chr3_+_9691117 0.299 ENST00000353332.5
ENST00000420925.1
ENST00000296003.4
ENST00000351233.5
MTMR14



myotubularin related protein 14



chr1_-_179112189 0.298 ENST00000512653.1
ENST00000344730.3
ABL2

c-abl oncogene 2, non-receptor tyrosine kinase

chr6_-_74161977 0.298 ENST00000370318.1
ENST00000370315.3
MB21D1

Mab-21 domain containing 1

chr8_-_81787006 0.297 ENST00000327835.3
ZNF704
zinc finger protein 704
chr4_+_2627159 0.296 ENST00000382839.3
ENST00000324666.5
ENST00000545951.1
ENST00000502458.1
ENST00000505311.1
FAM193A




family with sequence similarity 193, member A




chr21_-_43786634 0.295 ENST00000291527.2
TFF1
trefoil factor 1
chr10_-_71892555 0.295 ENST00000307864.1
AIFM2
apoptosis-inducing factor, mitochondrion-associated, 2
chr19_+_46531127 0.294 ENST00000601033.1
CTC-344H19.4
CTC-344H19.4
chr4_+_160188306 0.294 ENST00000510510.1
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr8_-_99954788 0.293 ENST00000523601.1
STK3
serine/threonine kinase 3
chr12_+_53645870 0.292 ENST00000329548.4
MFSD5
major facilitator superfamily domain containing 5
chr8_-_145013711 0.291 ENST00000345136.3
PLEC
plectin
chr10_+_7860460 0.290 ENST00000344293.5
TAF3
TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
chr1_+_207070775 0.288 ENST00000391929.3
ENST00000294984.2
ENST00000367093.3
IL24


interleukin 24


chr1_+_59762642 0.288 ENST00000371218.4
ENST00000303721.7
FGGY

FGGY carbohydrate kinase domain containing

chr22_+_23522552 0.288 ENST00000359540.3
ENST00000398512.5
BCR

breakpoint cluster region

chr2_-_219134343 0.286 ENST00000447885.1
ENST00000420660.1
AAMP

angio-associated, migratory cell protein

chrX_-_19689106 0.286 ENST00000379716.1
SH3KBP1
SH3-domain kinase binding protein 1
chr9_+_125137565 0.285 ENST00000373698.5
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr8_-_145025044 0.284 ENST00000322810.4
PLEC
plectin
chr2_-_3504587 0.284 ENST00000415131.1
ADI1
acireductone dioxygenase 1
chr7_-_143956815 0.283 ENST00000493325.1
OR2A7
olfactory receptor, family 2, subfamily A, member 7
chr1_-_179112173 0.283 ENST00000408940.3
ENST00000504405.1
ABL2

c-abl oncogene 2, non-receptor tyrosine kinase

chr11_-_78128811 0.281 ENST00000530915.1
ENST00000361507.4
GAB2

GRB2-associated binding protein 2

chr8_+_22435762 0.279 ENST00000456545.1
PDLIM2
PDZ and LIM domain 2 (mystique)
chr11_-_67120974 0.279 ENST00000539074.1
ENST00000312419.3
POLD4

polymerase (DNA-directed), delta 4, accessory subunit

chr7_-_24957699 0.278 ENST00000441059.1
ENST00000415162.1
OSBPL3

oxysterol binding protein-like 3

chr11_-_78052923 0.278 ENST00000340149.2
GAB2
GRB2-associated binding protein 2
chr16_-_69418553 0.276 ENST00000569542.2
TERF2
telomeric repeat binding factor 2
chr15_-_75017711 0.276 ENST00000567032.1
ENST00000564596.1
ENST00000566503.1
ENST00000395049.4
ENST00000395048.2
ENST00000379727.3
CYP1A1





cytochrome P450, family 1, subfamily A, polypeptide 1





chr6_-_28303901 0.276 ENST00000439158.1
ENST00000446474.1
ENST00000414431.1
ENST00000344279.6
ENST00000453745.1
ZSCAN31




zinc finger and SCAN domain containing 31




chr1_+_33219592 0.276 ENST00000373481.3
KIAA1522
KIAA1522
chr4_+_140222609 0.275 ENST00000296543.5
ENST00000398947.1
NAA15

N(alpha)-acetyltransferase 15, NatA auxiliary subunit

chr19_+_34895289 0.275 ENST00000246535.3
PDCD2L
programmed cell death 2-like
chrX_+_21959108 0.273 ENST00000457085.1
SMS
spermine synthase
chr19_-_14628645 0.272 ENST00000598235.1
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr4_+_671711 0.272 ENST00000400159.2
MYL5
myosin, light chain 5, regulatory
chr17_+_46185111 0.272 ENST00000582104.1
ENST00000584335.1
SNX11

sorting nexin 11

chr8_+_144766669 0.272 ENST00000526315.1
ENST00000532205.1
ZNF707

zinc finger protein 707

chr5_-_147211226 0.271 ENST00000296695.5
SPINK1
serine peptidase inhibitor, Kazal type 1
chr11_-_111749767 0.271 ENST00000542429.1
FDXACB1
ferredoxin-fold anticodon binding domain containing 1
chr14_+_67291158 0.270 ENST00000555456.1
GPHN
gephyrin
chrX_-_54069576 0.269 ENST00000445025.1
ENST00000322659.8
PHF8

PHD finger protein 8

chr12_-_116714564 0.269 ENST00000548743.1
MED13L
mediator complex subunit 13-like
chr12_-_53320245 0.269 ENST00000552150.1
KRT8
keratin 8
chr14_-_106963409 0.269 ENST00000390621.2
IGHV1-45
immunoglobulin heavy variable 1-45
chr11_+_107650219 0.269 ENST00000398067.1
AP001024.1
Uncharacterized protein
chr2_+_201450591 0.268 ENST00000374700.2
AOX1
aldehyde oxidase 1
chr5_-_180229833 0.268 ENST00000307826.4
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chrX_-_9002168 0.268 ENST00000327220.5
FAM9B
family with sequence similarity 9, member B
chrX_-_7066159 0.268 ENST00000486446.2
ENST00000412827.2
ENST00000424830.2
ENST00000381077.5
ENST00000540122.1
HDHD1




haloacid dehalogenase-like hydrolase domain containing 1




chr22_+_42949925 0.267 ENST00000327678.5
ENST00000340239.4
ENST00000407614.4
ENST00000335879.5
SERHL2



serine hydrolase-like 2



chr22_-_27620603 0.266 ENST00000418271.1
ENST00000444114.1
RP5-1172A22.1

RP5-1172A22.1

chr8_-_61880248 0.265 ENST00000525556.1
AC022182.3
AC022182.3
chr5_+_125800836 0.264 ENST00000511134.1
GRAMD3
GRAM domain containing 3
chr1_+_101361782 0.264 ENST00000357650.4
SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr22_+_18632666 0.263 ENST00000215794.7
USP18
ubiquitin specific peptidase 18
chr16_+_22518495 0.263 ENST00000541154.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chr5_+_147648393 0.262 ENST00000511106.1
ENST00000398450.4
SPINK13

serine peptidase inhibitor, Kazal type 13 (putative)

chr2_-_113594279 0.262 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B


interleukin 1, beta


chrX_-_54209640 0.258 ENST00000375180.2
ENST00000328235.4
ENST00000477084.1
FAM120C


family with sequence similarity 120C


chr3_-_48342795 0.257 ENST00000452211.1
ENST00000447724.1
ENST00000415053.1
ENST00000425930.1
ENST00000421967.1
ENST00000426723.1
ENST00000450160.1
ENST00000456495.1
ENST00000435684.1
ENST00000447314.1
ENST00000415644.1
ENST00000442597.1
NME6











NME/NM23 nucleoside diphosphate kinase 6











chrX_-_135962923 0.254 ENST00000565438.1
RBMX
RNA binding motif protein, X-linked
chr6_+_30295036 0.253 ENST00000376659.5
ENST00000428555.1
TRIM39

tripartite motif containing 39

chr3_+_32726620 0.253 ENST00000331889.6
ENST00000328834.5
CNOT10

CCR4-NOT transcription complex, subunit 10

chr7_-_27135591 0.253 ENST00000343060.4
ENST00000355633.5
HOXA1

homeobox A1

chr12_+_102271436 0.252 ENST00000544152.1
DRAM1
DNA-damage regulated autophagy modulator 1
chr3_-_196065248 0.252 ENST00000446879.1
ENST00000273695.3
TM4SF19

transmembrane 4 L six family member 19

chr12_+_72058130 0.251 ENST00000547843.1
THAP2
THAP domain containing, apoptosis associated protein 2
chr2_+_198318217 0.251 ENST00000409398.1
COQ10B
coenzyme Q10 homolog B (S. cerevisiae)
chr9_-_136203235 0.251 ENST00000372022.4
SURF6
surfeit 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.3 1.7 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.3 1.4 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.3 1.2 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.3 1.5 GO:0032474 otolith morphogenesis(GO:0032474)
0.3 0.3 GO:0017143 insecticide metabolic process(GO:0017143)
0.3 0.3 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.2 2.7 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.2 0.8 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.2 0.9 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.2 0.5 GO:0031247 actin rod assembly(GO:0031247)
0.2 0.6 GO:1903517 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.2 1.1 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.4 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 0.4 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.1 0.5 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 1.8 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.8 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.4 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 2.3 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.1 0.3 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.3 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.1 0.6 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.1 0.7 GO:2000668 dendritic cell apoptotic process(GO:0097048) regulation of dendritic cell apoptotic process(GO:2000668) positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.8 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.1 0.4 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 1.6 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.9 GO:2000373 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.1 0.5 GO:0072752 cellular response to rapamycin(GO:0072752)
0.1 0.3 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.1 0.2 GO:0071106 coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) NAD transport(GO:0043132) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.1 0.2 GO:0018194 N-terminal protein amino acid methylation(GO:0006480) N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573)
0.1 0.6 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.2 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 0.6 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 2.9 GO:0045730 respiratory burst(GO:0045730)
0.1 0.2 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.1 0.2 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 0.4 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.1 0.3 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 7.2 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 0.5 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.4 GO:0097368 membrane to membrane docking(GO:0022614) establishment of Sertoli cell barrier(GO:0097368)
0.1 0.2 GO:0072684 mitochondrial tRNA 3'-trailer cleavage, endonucleolytic(GO:0072684)
0.1 0.1 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.1 0.2 GO:0007037 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.1 0.2 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839) positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.3 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.1 0.4 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.1 0.1 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.3 GO:0015817 histidine transport(GO:0015817) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 0.2 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.1 1.1 GO:0015884 folic acid transport(GO:0015884)
0.1 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.6 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.4 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.4 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.1 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.3 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.1 0.6 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.1 0.2 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 0.5 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.1 0.3 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.1 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.2 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 0.3 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.1 0.1 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.1 1.0 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.2 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.2 GO:0021938 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938) notochord regression(GO:0060032)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.2 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.0 0.4 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.1 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.2 GO:0035803 egg coat formation(GO:0035803)
0.0 0.3 GO:2000782 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.3 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.3 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.0 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.5 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.1 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.2 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.3 GO:0009799 specification of symmetry(GO:0009799) determination of bilateral symmetry(GO:0009855)
0.0 0.2 GO:0070895 transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895)
0.0 0.1 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.0 0.4 GO:0071351 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.0 0.3 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.2 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.1 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.0 0.2 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.2 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.6 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.4 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.2 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.3 GO:1901295 regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.5 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.4 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.1 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.0 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.3 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.2 GO:0060467 negative regulation of fertilization(GO:0060467)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.2 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.1 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:1901355 response to rapamycin(GO:1901355) response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.2 GO:0048389 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) deltoid tuberosity development(GO:0035993) intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) pattern specification involved in mesonephros development(GO:0061227) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.2 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.3 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 0.3 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.2 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.2 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.3 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.2 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.3 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.3 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.0 0.2 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.3 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.0 0.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.4 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.1 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.1 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0 0.1 GO:0051598 meiotic recombination checkpoint(GO:0051598)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.2 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.2 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0 0.3 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0 0.1 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0 0.2 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.6 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.1 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.0 0.1 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.3 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.9 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.1 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.2 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.1 GO:1903979 negative regulation of microglial cell activation(GO:1903979)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.5 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.1 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0 0.1 GO:0060492 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0 0.1 GO:1900368 pre-miRNA export from nucleus(GO:0035281) regulation of RNA interference(GO:1900368)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.2 GO:0051177 meiotic DNA recombinase assembly(GO:0000707) meiotic sister chromatid cohesion(GO:0051177)
0.0 0.3 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.4 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.5 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 0.2 GO:0034770 histone H4-K20 methylation(GO:0034770)
0.0 0.4 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.0 GO:0072194 renal artery morphogenesis(GO:0061441) kidney smooth muscle tissue development(GO:0072194)
0.0 0.2 GO:0006710 androgen catabolic process(GO:0006710)
0.0 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.1 GO:1901340 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) negative regulation of store-operated calcium channel activity(GO:1901340)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.2 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.1 GO:0044053 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.0 0.1 GO:0035283 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.0 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.5 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.3 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.3 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.1 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.0 0.5 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 0.0 GO:0045954 positive regulation of leukocyte mediated cytotoxicity(GO:0001912) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.1 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.1 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.1 GO:0090307 mitotic spindle assembly(GO:0090307)
0.0 0.1 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.9 GO:0036336 dendritic cell migration(GO:0036336)
0.0 0.5 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.1 GO:0045080 positive regulation of chemokine biosynthetic process(GO:0045080)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.0 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.0 0.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.3 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.2 GO:0021603 cranial nerve formation(GO:0021603)
0.0 0.3 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.1 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.2 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.3 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 2.3 GO:0070268 cornification(GO:0070268)
0.0 0.5 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.2 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.2 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.2 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.0 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.1 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
0.0 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.1 GO:0048817 negative regulation of hair follicle maturation(GO:0048817) negative regulation of hair follicle development(GO:0051799)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:0061015 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.0 0.1 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0018277 protein deamination(GO:0018277)
0.0 0.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.3 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.0 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.0 GO:0080154 regulation of fertilization(GO:0080154)
0.0 0.0 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.3 GO:0000052 citrulline metabolic process(GO:0000052)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.7 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.2 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.2 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.1 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.0 0.2 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 0.1 GO:0023035 CD40 signaling pathway(GO:0023035)
0.0 0.1 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.0 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.2 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.4 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.0 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.0 0.0 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.8 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.1 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 1.3 GO:0010595 positive regulation of endothelial cell migration(GO:0010595)
0.0 0.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.2 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.2 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.0 GO:0010446 response to alkaline pH(GO:0010446)
0.0 0.1 GO:0032439 endosome localization(GO:0032439)
0.0 0.0 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.0 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.2 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.1 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 1.1 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.0 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.0 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.1 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.3 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.0 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.0 0.5 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.0 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.1 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.0 GO:2000858 mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of mineralocorticoid secretion(GO:2000855) regulation of aldosterone secretion(GO:2000858)
0.0 0.2 GO:1901678 iron coordination entity transport(GO:1901678)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.1 GO:0033504 floor plate development(GO:0033504)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.7 GO:0032010 phagolysosome(GO:0032010)
0.1 0.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.6 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.5 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 0.2 GO:0034515 proteasome storage granule(GO:0034515)
0.1 0.3 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.1 0.3 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 0.4 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.2 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.7 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.1 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.0 0.2 GO:0031213 RSF complex(GO:0031213)
0.0 0.5 GO:0000322 storage vacuole(GO:0000322)
0.0 0.3 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.3 GO:0001652 granular component(GO:0001652)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 0.9 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.4 GO:0060091 kinocilium(GO:0060091)
0.0 0.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0036117 hyaluranon cable(GO:0036117)
0.0 0.5 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.3 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.6 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.4 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0042565 RNA nuclear export complex(GO:0042565)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.3 GO:0030061 mitochondrial crista(GO:0030061)
0.0 1.5 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.0 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.5 GO:0000800 lateral element(GO:0000800)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0001940 male pronucleus(GO:0001940)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.6 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.4 GO:0005915 zonula adherens(GO:0005915)
0.0 0.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.1 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 1.0 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0034709 methylosome(GO:0034709)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0071546 pi-body(GO:0071546)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.9 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.2 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.1 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.0 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.0 0.6 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.3 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.0 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.0 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 1.0 GO:0005882 intermediate filament(GO:0005882)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0005902 microvillus(GO:0005902)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.6 7.6 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.4 1.2 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.3 0.9 GO:0008859 exoribonuclease II activity(GO:0008859)
0.2 1.3 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.2 1.7 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 0.5 GO:0016768 spermine synthase activity(GO:0016768)
0.2 0.5 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 2.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.8 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.6 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.1 0.8 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.3 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 1.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.4 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.5 GO:0051373 FATZ binding(GO:0051373)
0.1 0.3 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.3 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 0.3 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.1 0.6 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 0.6 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 0.3 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.2 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 0.2 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.1 1.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.8 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.4 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.1 0.5 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.3 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1 0.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 0.5 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.2 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.1 1.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.3 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.5 GO:0046790 virion binding(GO:0046790)
0.1 0.2 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.1 1.1 GO:0005542 folic acid binding(GO:0005542)
0.1 0.4 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.9 GO:0042923 neuropeptide binding(GO:0042923)
0.1 0.5 GO:0030621 U4 snRNA binding(GO:0030621)
0.1 0.2 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.1 0.2 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.1 0.6 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.7 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.3 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.4 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.3 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.2 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.1 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.0 0.2 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 2.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.1 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.0 0.6 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.1 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.1 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.3 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.2 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 0.2 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.6 GO:0000150 recombinase activity(GO:0000150)
0.0 0.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 2.3 GO:0030551 cyclic nucleotide binding(GO:0030551)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.1 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.4 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.3 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.1 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.5 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.1 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.0 0.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 0.9 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0004766 spermidine synthase activity(GO:0004766)
0.0 0.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.4 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.1 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.2 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.0 0.1 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.0 0.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0002054 nucleobase binding(GO:0002054) purine nucleobase binding(GO:0002060)
0.0 0.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.0 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.0 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.8 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.0 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.7 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.0 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.0 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.0 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.0 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.5 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.0 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.1 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0 0.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0043199 sulfate binding(GO:0043199)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.0 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.5 GO:0016773 phosphotransferase activity, alcohol group as acceptor(GO:0016773)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 1.5 PID_IL23_PATHWAY IL23-mediated signaling events
0.0 0.1 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.0 3.0 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.1 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 0.1 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.4 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.5 PID_ATM_PATHWAY ATM pathway
0.0 2.0 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.4 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.4 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.0 0.2 PID_IL2_1PATHWAY IL2-mediated signaling events
0.0 1.6 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.9 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.5 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.6 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.1 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.0 0.2 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.6 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.0 0.1 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 0.5 ST_B_CELL_ANTIGEN_RECEPTOR B Cell Antigen Receptor
0.0 0.4 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.2 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.6 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.3 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 0.1 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 10.2 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 2.6 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.4 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 3.0 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.6 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.8 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.0 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.4 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.3 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.1 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.5 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.0 1.2 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 1.3 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.7 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.1 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.1 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.4 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.1 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.0 1.8 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.1 REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.3 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.6 REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ Genes involved in Cyclin E associated events during G1/S transition
0.0 0.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.2 REACTOME_ER_PHAGOSOME_PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.1 REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_ Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0 0.6 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.1 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.3 REACTOME_PD1_SIGNALING Genes involved in PD-1 signaling
0.0 0.3 REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.5 REACTOME_BOTULINUM_NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 0.2 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.1 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.1 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.3 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.5 REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.4 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.4 REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.5 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.4 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.1 REACTOME_DOWNSTREAM_TCR_SIGNALING Genes involved in Downstream TCR signaling
0.0 0.5 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.5 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.8 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.3 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.1 REACTOME_AQUAPORIN_MEDIATED_TRANSPORT Genes involved in Aquaporin-mediated transport
0.0 0.3 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules