Motif ID: STAT5A

Z-value: 0.863


Transcription factors associated with STAT5A:

Gene SymbolEntrez IDGene Name
STAT5A ENSG00000126561.12 STAT5A

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
STAT5Ahg19_v2_chr17_+_40440481_40440561-0.314.2e-01Click!


Activity profile for motif STAT5A.

activity profile for motif STAT5A


Sorted Z-values histogram for motif STAT5A

Sorted Z-values for motif STAT5A



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT5A

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_100841930 0.758 ENST00000555031.1
ENST00000553395.1
ENST00000553545.1
ENST00000344102.5
ENST00000556338.1
ENST00000392882.2
ENST00000553934.1
WARS






tryptophanyl-tRNA synthetase






chr14_-_100841670 0.755 ENST00000557297.1
ENST00000555813.1
ENST00000557135.1
ENST00000556698.1
ENST00000554509.1
ENST00000555410.1
WARS





tryptophanyl-tRNA synthetase





chr14_-_100841794 0.749 ENST00000556295.1
ENST00000554820.1
WARS

tryptophanyl-tRNA synthetase

chr17_-_34207295 0.570 ENST00000463941.1
ENST00000293272.3
CCL5

chemokine (C-C motif) ligand 5

chr12_+_113416191 0.495 ENST00000342315.4
ENST00000392583.2
OAS2

2'-5'-oligoadenylate synthetase 2, 69/71kDa

chr4_-_76957214 0.460 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr11_+_107650219 0.457 ENST00000398067.1
AP001024.1
Uncharacterized protein
chr22_+_44761431 0.429 ENST00000406912.1
RP1-32I10.10
Uncharacterized protein
chr3_+_187086120 0.418 ENST00000259030.2
RTP4
receptor (chemosensory) transporter protein 4
chr17_-_39928106 0.385 ENST00000540235.1
JUP
junction plakoglobin
chr12_+_113416340 0.357 ENST00000552756.1
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr17_-_39780634 0.309 ENST00000577817.2
KRT17
keratin 17
chrX_+_18725758 0.243 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1


protein phosphatase, EF-hand calcium binding domain 1


chr2_+_163200848 0.241 ENST00000233612.4
GCA
grancalcin, EF-hand calcium binding protein
chr3_+_149191723 0.239 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr11_+_72281681 0.234 ENST00000450804.3
RP11-169D4.1
RP11-169D4.1
chr12_-_117318788 0.233 ENST00000550505.1
HRK
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr1_-_147245484 0.232 ENST00000271348.2
GJA5
gap junction protein, alpha 5, 40kDa
chrX_+_106045891 0.231 ENST00000357242.5
ENST00000310452.2
ENST00000481617.2
ENST00000276175.3
TBC1D8B



TBC1 domain family, member 8B (with GRAM domain)



chr19_+_36203830 0.229 ENST00000262630.3
ZBTB32
zinc finger and BTB domain containing 32
chr12_+_113416265 0.226 ENST00000449768.2
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr10_-_33625154 0.218 ENST00000265371.4
NRP1
neuropilin 1
chr12_-_8814669 0.215 ENST00000535411.1
ENST00000540087.1
MFAP5

microfibrillar associated protein 5

chrX_-_15619076 0.214 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr19_+_44507091 0.203 ENST00000429154.2
ENST00000585632.1
ZNF230

zinc finger protein 230

chr12_-_8815215 0.199 ENST00000544889.1
ENST00000543369.1
MFAP5

microfibrillar associated protein 5

chr1_+_197237352 0.198 ENST00000538660.1
ENST00000367400.3
ENST00000367399.2
CRB1


crumbs homolog 1 (Drosophila)


chr9_-_110251836 0.198 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr1_-_159046617 0.198 ENST00000368130.4
AIM2
absent in melanoma 2
chr3_-_124653579 0.195 ENST00000478191.1
ENST00000311075.3
MUC13

mucin 13, cell surface associated

chr16_-_67517716 0.192 ENST00000290953.2
AGRP
agouti related protein homolog (mouse)
chr12_-_8815299 0.190 ENST00000535336.1
MFAP5
microfibrillar associated protein 5
chr7_-_139727118 0.183 ENST00000484111.1
PARP12
poly (ADP-ribose) polymerase family, member 12
chr1_+_12123414 0.183 ENST00000263932.2
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr2_-_38303218 0.182 ENST00000407341.1
ENST00000260630.3
CYP1B1

cytochrome P450, family 1, subfamily B, polypeptide 1

chr2_+_47043832 0.180 ENST00000422294.1
AC016722.2
long intergenic non-protein coding RNA 1119
chr19_+_35168567 0.179 ENST00000457781.2
ENST00000505163.1
ENST00000505242.1
ENST00000423823.2
ENST00000507959.1
ENST00000446502.2
ZNF302





zinc finger protein 302





chr10_+_104629199 0.176 ENST00000369880.3
AS3MT
arsenic (+3 oxidation state) methyltransferase
chr12_+_44152740 0.171 ENST00000440781.2
ENST00000431837.1
ENST00000550616.1
ENST00000448290.2
ENST00000551736.1
IRAK4




interleukin-1 receptor-associated kinase 4




chr1_-_94374946 0.169 ENST00000370238.3
GCLM
glutamate-cysteine ligase, modifier subunit
chr8_+_70404996 0.169 ENST00000402687.4
ENST00000419716.3
SULF1

sulfatase 1

chr2_-_113594279 0.168 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B


interleukin 1, beta


chr3_-_69249863 0.165 ENST00000478263.1
ENST00000462512.1
FRMD4B

FERM domain containing 4B

chr15_+_59910132 0.162 ENST00000559200.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr1_+_12123463 0.161 ENST00000417814.2
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr2_+_112812778 0.160 ENST00000283206.4
TMEM87B
transmembrane protein 87B
chr19_+_35168633 0.159 ENST00000505365.2
ZNF302
zinc finger protein 302
chr3_-_148939835 0.158 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr19_+_44598492 0.158 ENST00000589680.1
ZNF224
zinc finger protein 224
chr22_-_29137771 0.157 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
CHEK2









checkpoint kinase 2









chr1_-_89488510 0.156 ENST00000564665.1
ENST00000370481.4
GBP3

guanylate binding protein 3

chr6_-_39693111 0.155 ENST00000373215.3
ENST00000538893.1
ENST00000287152.7
ENST00000373216.3
KIF6



kinesin family member 6



chrY_+_15418467 0.150 ENST00000595988.1
AC010877.1
Uncharacterized protein
chr11_+_58912240 0.149 ENST00000527629.1
ENST00000361723.3
ENST00000531408.1
FAM111A


family with sequence similarity 111, member A


chr1_+_158975744 0.147 ENST00000426592.2
IFI16
interferon, gamma-inducible protein 16
chr5_-_67730240 0.145 ENST00000507733.1
CTC-537E7.3
CTC-537E7.3
chr15_+_45938079 0.145 ENST00000561493.1
SQRDL
sulfide quinone reductase-like (yeast)
chr6_-_28973037 0.141 ENST00000377179.3
ZNF311
zinc finger protein 311
chr1_+_150245177 0.141 ENST00000369098.3
C1orf54
chromosome 1 open reading frame 54
chr1_-_144994840 0.136 ENST00000369351.3
ENST00000369349.3
PDE4DIP

phosphodiesterase 4D interacting protein

chr11_+_123325106 0.136 ENST00000525757.1
LINC01059
long intergenic non-protein coding RNA 1059
chr6_-_32820529 0.135 ENST00000425148.2
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr19_+_47835404 0.135 ENST00000595464.1
C5AR2
complement component 5a receptor 2
chr1_-_100643765 0.134 ENST00000370137.1
ENST00000370138.1
ENST00000342895.3
LRRC39


leucine rich repeat containing 39


chr12_-_10324716 0.132 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
OLR1



oxidized low density lipoprotein (lectin-like) receptor 1



chr15_+_48051920 0.132 ENST00000559196.1
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr2_-_133104839 0.131 ENST00000608279.1
RP11-725P16.2
RP11-725P16.2
chr1_-_162381907 0.130 ENST00000367929.2
ENST00000359567.3
SH2D1B

SH2 domain containing 1B

chr4_-_186732048 0.130 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2




sorbin and SH3 domain containing 2




chr1_-_55230165 0.128 ENST00000371279.3
PARS2
prolyl-tRNA synthetase 2, mitochondrial (putative)
chr11_-_82997420 0.128 ENST00000455220.2
ENST00000529689.1
CCDC90B

coiled-coil domain containing 90B

chr22_+_27068766 0.127 ENST00000435162.1
ENST00000437071.1
ENST00000440816.1
ENST00000421253.1
CTA-211A9.5



CTA-211A9.5



chr22_-_29138386 0.127 ENST00000544772.1
CHEK2
checkpoint kinase 2
chr1_-_145075847 0.126 ENST00000530740.1
ENST00000369359.4
PDE4DIP

phosphodiesterase 4D interacting protein

chr1_+_59775752 0.124 ENST00000371212.1
FGGY
FGGY carbohydrate kinase domain containing
chr3_-_64211112 0.124 ENST00000295902.6
PRICKLE2
prickle homolog 2 (Drosophila)
chr5_-_180288248 0.124 ENST00000512132.1
ENST00000506439.1
ENST00000502412.1
ENST00000359141.6
ZFP62



ZFP62 zinc finger protein



chr6_-_31689456 0.123 ENST00000495859.1
ENST00000375819.2
LY6G6C

lymphocyte antigen 6 complex, locus G6C

chr13_+_76413852 0.122 ENST00000533809.2
LMO7
LIM domain 7
chr6_-_105307711 0.122 ENST00000519645.1
ENST00000262903.4
ENST00000369125.2
HACE1


HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1


chr1_+_46640750 0.121 ENST00000372003.1
TSPAN1
tetraspanin 1
chr5_-_64777733 0.119 ENST00000381055.3
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr1_+_35247859 0.119 ENST00000373362.3
GJB3
gap junction protein, beta 3, 31kDa
chr15_-_79576156 0.119 ENST00000560452.1
ENST00000560872.1
ENST00000560732.1
ENST00000559979.1
ENST00000560533.1
ENST00000559225.1
RP11-17L5.4





RP11-17L5.4





chr7_+_150382781 0.118 ENST00000223293.5
ENST00000474605.1
GIMAP2

GTPase, IMAP family member 2

chr7_+_102715573 0.118 ENST00000434153.1
ARMC10
armadillo repeat containing 10
chr3_-_172019686 0.117 ENST00000596321.1
AC092964.2
Uncharacterized protein
chr6_+_7541808 0.117 ENST00000379802.3
DSP
desmoplakin
chr5_-_145214848 0.115 ENST00000505416.1
ENST00000334744.4
ENST00000358004.2
ENST00000511435.1
PRELID2



PRELI domain containing 2



chr22_+_29138013 0.115 ENST00000216027.3
ENST00000398941.2
HSCB

HscB mitochondrial iron-sulfur cluster co-chaperone

chr4_+_25378912 0.115 ENST00000510092.1
ENST00000505991.1
ANAPC4

anaphase promoting complex subunit 4

chr4_-_123843597 0.114 ENST00000510735.1
ENST00000304430.5
NUDT6

nudix (nucleoside diphosphate linked moiety X)-type motif 6

chr3_+_132136331 0.114 ENST00000260818.6
DNAJC13
DnaJ (Hsp40) homolog, subfamily C, member 13
chr6_-_28303901 0.112 ENST00000439158.1
ENST00000446474.1
ENST00000414431.1
ENST00000344279.6
ENST00000453745.1
ZSCAN31




zinc finger and SCAN domain containing 31




chr4_-_38858428 0.112 ENST00000506146.1
ENST00000436693.2
ENST00000508254.1
ENST00000514655.1
TLR1
TLR6


toll-like receptor 1
toll-like receptor 6


chr17_-_72619869 0.112 ENST00000392619.1
ENST00000426295.2
CD300E

CD300e molecule

chr4_+_108815402 0.110 ENST00000503385.1
SGMS2
sphingomyelin synthase 2
chr14_+_61449197 0.110 ENST00000533744.2
SLC38A6
solute carrier family 38, member 6
chr19_+_52074502 0.110 ENST00000545217.1
ENST00000262259.2
ENST00000596504.1
ZNF175


zinc finger protein 175


chr17_-_36997708 0.110 ENST00000398575.4
C17orf98
chromosome 17 open reading frame 98
chr8_-_61880248 0.110 ENST00000525556.1
AC022182.3
AC022182.3
chr21_+_34697258 0.109 ENST00000442071.1
ENST00000442357.2
IFNAR1

interferon (alpha, beta and omega) receptor 1

chr19_+_52430688 0.108 ENST00000391794.4
ENST00000599683.1
ENST00000600853.1
ZNF613


zinc finger protein 613


chr16_-_75498308 0.107 ENST00000569540.1
TMEM170A
transmembrane protein 170A
chr12_+_102271129 0.107 ENST00000258534.8
DRAM1
DNA-damage regulated autophagy modulator 1
chr8_-_112248400 0.106 ENST00000519506.1
ENST00000522778.1
RP11-946L20.4

RP11-946L20.4

chr4_+_25378826 0.105 ENST00000315368.3
ANAPC4
anaphase promoting complex subunit 4
chr17_+_67498295 0.105 ENST00000589295.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr9_+_273038 0.105 ENST00000487230.1
ENST00000469391.1
DOCK8

dedicator of cytokinesis 8

chr13_+_32889605 0.103 ENST00000380152.3
ENST00000544455.1
ENST00000530893.2
BRCA2


breast cancer 2, early onset


chr19_+_44617511 0.103 ENST00000262894.6
ENST00000588926.1
ENST00000592780.1
ZNF225


zinc finger protein 225


chr6_-_83775489 0.103 ENST00000369747.3
UBE3D
ubiquitin protein ligase E3D
chr17_+_17876127 0.103 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
LRRC48









leucine rich repeat containing 48









chr20_+_10015678 0.102 ENST00000378392.1
ENST00000378380.3
ANKEF1

ankyrin repeat and EF-hand domain containing 1

chr2_-_99917639 0.102 ENST00000308528.4
LYG1
lysozyme G-like 1
chr1_-_144994909 0.102 ENST00000369347.4
ENST00000369354.3
PDE4DIP

phosphodiesterase 4D interacting protein

chr9_-_97402413 0.101 ENST00000414122.1
FBP1
fructose-1,6-bisphosphatase 1
chr2_-_165630264 0.101 ENST00000452626.1
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr3_-_160823040 0.101 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
B3GALNT1






beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)






chr15_-_74659978 0.101 ENST00000541301.1
ENST00000416978.1
ENST00000268053.6
CYP11A1


cytochrome P450, family 11, subfamily A, polypeptide 1


chr19_+_58790314 0.100 ENST00000196548.5
ENST00000608843.1
ZNF8
ZNF8
Zinc finger protein 8
zinc finger protein 8
chr8_-_12612962 0.100 ENST00000398246.3
LONRF1
LON peptidase N-terminal domain and ring finger 1
chr3_+_112709804 0.100 ENST00000383677.3
GTPBP8
GTP-binding protein 8 (putative)
chr15_+_67547113 0.100 ENST00000512104.1
ENST00000358767.3
ENST00000546225.1
IQCH


IQ motif containing H


chr12_-_15103621 0.099 ENST00000536592.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr4_-_165305086 0.099 ENST00000507270.1
ENST00000514618.1
ENST00000503008.1
MARCH1


membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase


chr11_-_111636772 0.098 ENST00000531373.1
PPP2R1B
protein phosphatase 2, regulatory subunit A, beta
chr7_-_158937633 0.097 ENST00000262178.2
VIPR2
vasoactive intestinal peptide receptor 2
chr12_+_133657461 0.096 ENST00000412146.2
ENST00000544426.1
ENST00000440984.2
ENST00000319849.3
ENST00000440550.2
ZNF140




zinc finger protein 140




chr12_-_12503156 0.096 ENST00000543314.1
ENST00000396349.3
MANSC1

MANSC domain containing 1

chr22_-_37640277 0.096 ENST00000401529.3
ENST00000249071.6
RAC2

ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)

chr18_+_44526744 0.096 ENST00000585469.1
KATNAL2
katanin p60 subunit A-like 2
chr2_-_204398141 0.096 ENST00000428637.1
RAPH1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr20_+_33464238 0.095 ENST00000360596.2
ACSS2
acyl-CoA synthetase short-chain family member 2
chr12_+_131438496 0.095 ENST00000543826.1
GPR133
G protein-coupled receptor 133
chr20_+_33464407 0.094 ENST00000253382.5
ACSS2
acyl-CoA synthetase short-chain family member 2
chr1_-_54405773 0.094 ENST00000371376.1
HSPB11
heat shock protein family B (small), member 11
chr3_+_101443476 0.094 ENST00000327230.4
ENST00000494050.1
CEP97

centrosomal protein 97kDa

chr17_-_59940830 0.093 ENST00000259008.2
BRIP1
BRCA1 interacting protein C-terminal helicase 1
chr15_+_63414760 0.093 ENST00000557972.1
LACTB
lactamase, beta
chr19_+_57791419 0.092 ENST00000537645.1
ZNF460
zinc finger protein 460
chr19_+_40503013 0.092 ENST00000595225.1
ZNF546
zinc finger protein 546
chr7_-_158937544 0.092 ENST00000421760.2
ENST00000402066.1
VIPR2

vasoactive intestinal peptide receptor 2

chr10_+_30722866 0.091 ENST00000263056.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr7_+_30589829 0.091 ENST00000579437.1
RP4-777O23.1
RP4-777O23.1
chr17_-_15501932 0.091 ENST00000583965.1
CDRT1
CMT1A duplicated region transcript 1
chr15_+_50474385 0.091 ENST00000267842.5
SLC27A2
solute carrier family 27 (fatty acid transporter), member 2
chr9_-_94877658 0.090 ENST00000262554.2
ENST00000337841.4
SPTLC1

serine palmitoyltransferase, long chain base subunit 1

chr14_+_61789382 0.090 ENST00000555082.1
PRKCH
protein kinase C, eta
chr6_+_28911654 0.090 ENST00000377186.3
C6orf100
chromosome 6 open reading frame 100
chr15_+_50474412 0.089 ENST00000380902.4
SLC27A2
solute carrier family 27 (fatty acid transporter), member 2
chr2_+_74056066 0.089 ENST00000339566.3
ENST00000409707.1
ENST00000452725.1
ENST00000432295.2
ENST00000424659.1
ENST00000394073.1
STAMBP





STAM binding protein





chr11_+_32112431 0.089 ENST00000054950.3
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr11_-_82997013 0.089 ENST00000529073.1
ENST00000529611.1
CCDC90B

coiled-coil domain containing 90B

chr11_+_7506837 0.089 ENST00000528758.1
OLFML1
olfactomedin-like 1
chr2_-_171627269 0.088 ENST00000442456.1
AC007405.4
AC007405.4
chr4_+_47487285 0.088 ENST00000273859.3
ENST00000504445.1
ATP10D

ATPase, class V, type 10D

chr15_-_42565023 0.088 ENST00000566474.1
TMEM87A
transmembrane protein 87A
chr19_-_44809121 0.087 ENST00000591609.1
ENST00000589799.1
ENST00000291182.4
ENST00000589248.1
ZNF235



zinc finger protein 235



chrX_+_129473916 0.087 ENST00000545805.1
ENST00000543953.1
ENST00000218197.5
SLC25A14


solute carrier family 25 (mitochondrial carrier, brain), member 14


chr18_+_61637159 0.087 ENST00000397985.2
ENST00000353706.2
ENST00000542677.1
ENST00000397988.3
ENST00000448851.1
SERPINB8




serpin peptidase inhibitor, clade B (ovalbumin), member 8




chr4_+_142558078 0.087 ENST00000529613.1
IL15
interleukin 15
chr11_+_121163466 0.087 ENST00000527762.1
ENST00000534230.1
ENST00000392789.2
SC5D


sterol-C5-desaturase


chr5_+_145583107 0.086 ENST00000506502.1
RBM27
RNA binding motif protein 27
chr4_+_87928353 0.086 ENST00000511722.1
AFF1
AF4/FMR2 family, member 1
chr19_+_17516624 0.086 ENST00000596322.1
ENST00000600008.1
ENST00000601885.1
CTD-2521M24.9


CTD-2521M24.9


chr16_-_29479154 0.086 ENST00000549950.1
RP11-345J4.3
Uncharacterized protein
chr6_+_108616243 0.086 ENST00000421954.1
LACE1
lactation elevated 1
chr19_+_58193337 0.085 ENST00000601064.1
ENST00000282296.5
ENST00000356715.4
ZNF551


zinc finger protein 551


chr19_+_5681011 0.085 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
HSD11B1L









hydroxysteroid (11-beta) dehydrogenase 1-like









chr12_-_15114492 0.085 ENST00000541546.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr12_+_19556998 0.085 ENST00000541908.1
AEBP2
AE binding protein 2
chr8_+_124194752 0.084 ENST00000318462.6
FAM83A
family with sequence similarity 83, member A
chr8_+_27629459 0.084 ENST00000523566.1
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr9_+_86238016 0.084 ENST00000530832.1
ENST00000405990.3
ENST00000376417.4
ENST00000376419.4
IDNK



idnK, gluconokinase homolog (E. coli)



chr3_-_4927447 0.084 ENST00000449914.1
AC018816.3
Uncharacterized protein
chr11_-_58378759 0.083 ENST00000601906.1
AP001350.1
Uncharacterized protein
chr12_+_66696322 0.083 ENST00000247815.4
HELB
helicase (DNA) B
chr14_+_58894404 0.083 ENST00000554463.1
ENST00000555833.1
KIAA0586

KIAA0586

chr14_-_68162438 0.083 ENST00000557273.1
ENST00000428130.2
RDH11

retinol dehydrogenase 11 (all-trans/9-cis/11-cis)

chr4_-_123844084 0.082 ENST00000339154.2
NUDT6
nudix (nucleoside diphosphate linked moiety X)-type motif 6
chr14_-_51135036 0.082 ENST00000324679.4
SAV1
salvador homolog 1 (Drosophila)
chr3_-_50649192 0.081 ENST00000443053.2
ENST00000348721.3
CISH

cytokine inducible SH2-containing protein

chr20_+_33464368 0.080 ENST00000484354.1
ENST00000493805.2
ENST00000473172.1
ACSS2


acyl-CoA synthetase short-chain family member 2


chr15_-_42565221 0.080 ENST00000563371.1
ENST00000568400.1
ENST00000568432.1
TMEM87A


transmembrane protein 87A


chr19_+_35225060 0.080 ENST00000599244.1
ENST00000392232.3
ZNF181

zinc finger protein 181

chr11_+_9685604 0.080 ENST00000447399.2
ENST00000318950.6
SWAP70

SWAP switching B-cell complex 70kDa subunit

chr3_+_11314072 0.080 ENST00000444619.1
ATG7
autophagy related 7
chr2_-_152146385 0.079 ENST00000414946.1
ENST00000243346.5
NMI

N-myc (and STAT) interactor

chrX_+_24711997 0.079 ENST00000379068.3
ENST00000379059.3
POLA1

polymerase (DNA directed), alpha 1, catalytic subunit

chr4_+_142557771 0.079 ENST00000514653.1
IL15
interleukin 15
chr19_-_29218538 0.078 ENST00000592347.1
ENST00000586528.1
AC005307.3

AC005307.3

chr20_-_18447667 0.078 ENST00000262547.5
ENST00000329494.5
ENST00000357236.4
DZANK1


double zinc ribbon and ankyrin repeat domains 1


chr12_+_72058130 0.078 ENST00000547843.1
THAP2
THAP domain containing, apoptosis associated protein 2
chr10_+_90750378 0.078 ENST00000355740.2
ENST00000352159.4
FAS

Fas cell surface death receptor

chr20_+_58571419 0.077 ENST00000244049.3
ENST00000350849.6
ENST00000456106.1
CDH26


cadherin 26


chrX_-_148571884 0.077 ENST00000537071.1
IDS
iduronate 2-sulfatase
chr1_+_111415757 0.077 ENST00000429072.2
ENST00000271324.5
CD53

CD53 molecule

chr11_-_122932730 0.077 ENST00000532182.1
ENST00000524590.1
ENST00000528292.1
ENST00000533540.1
ENST00000525463.1
HSPA8




heat shock 70kDa protein 8




chr7_-_132766818 0.077 ENST00000262570.5
CHCHD3
coiled-coil-helix-coiled-coil-helix domain containing 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.3 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.6 GO:2000503 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.3 GO:0045553 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.1 0.3 GO:0086055 atrial ventricular junction remodeling(GO:0003294) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
0.1 1.1 GO:0018377 protein myristoylation(GO:0018377)
0.1 0.3 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.6 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 0.2 GO:0045062 extrathymic T cell selection(GO:0045062)
0.1 0.3 GO:0019427 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.1 0.2 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 0.4 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.2 GO:0034130 toll-like receptor 1 signaling pathway(GO:0034130)
0.0 0.2 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.2 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.0 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.0 0.2 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 0.1 GO:0006433 prolyl-tRNA aminoacylation(GO:0006433)
0.0 0.2 GO:0097069 response to human chorionic gonadotropin(GO:0044752) cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.0 0.1 GO:0070408 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.0 0.5 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.2 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.1 GO:0016237 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521)
0.0 0.3 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.0 0.2 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.1 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.0 0.1 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.0 0.1 GO:0046967 cytosol to ER transport(GO:0046967)
0.0 0.1 GO:0052214 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.1 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.1 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 0.1 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.2 GO:0031622 positive regulation of fever generation(GO:0031622)
0.0 0.1 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.1 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.0 0.1 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.0 0.1 GO:0000706 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.0 0.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.0 0.1 GO:0071790 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.0 0.2 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0046081 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.0 0.1 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.1 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.2 GO:0070269 pyroptosis(GO:0070269)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:1904504 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0 0.2 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.0 0.1 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.0 0.0 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.0 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.8 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.0 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.5 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.1 GO:0060143 positive regulation of myotube differentiation(GO:0010831) regulation of syncytium formation by plasma membrane fusion(GO:0060142) positive regulation of syncytium formation by plasma membrane fusion(GO:0060143) regulation of myoblast fusion(GO:1901739) positive regulation of myoblast fusion(GO:1901741)
0.0 0.0 GO:1902824 positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.0 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.0 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.0 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.1 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:1903061 positive regulation of protein lipidation(GO:1903061)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.0 GO:0001570 vasculogenesis(GO:0001570)
0.0 0.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.0 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.0 GO:1903059 regulation of protein lipidation(GO:1903059)
0.0 0.0 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.0 0.1 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0 0.0 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.0 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.0 0.2 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.2 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.3 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.0 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.1 GO:0070701 mucus layer(GO:0070701)
0.0 0.0 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.0 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.3 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.3 GO:0086079 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
0.1 0.4 GO:0005199 structural constituent of cell wall(GO:0005199)
0.1 1.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.6 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.4 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.3 GO:0004905 type I interferon receptor activity(GO:0004905)
0.1 0.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.2 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.0 0.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.1 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.0 0.1 GO:0004827 proline-tRNA ligase activity(GO:0004827)
0.0 0.2 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.1 GO:0019150 D-ribulokinase activity(GO:0019150)
0.0 0.1 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.0 0.3 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0004423 iduronate-2-sulfatase activity(GO:0004423)
0.0 0.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.0 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.2 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.1 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0 0.1 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.0 0.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 0.1 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.0 0.1 GO:0070704 C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704)
0.0 0.1 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.1 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.0 0.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.1 GO:0046979 TAP2 binding(GO:0046979)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.0 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.0 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.0 GO:0036033 mediator complex binding(GO:0036033)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.5 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.0 0.0 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.2 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.0 0.4 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.0 0.3 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.2 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.9 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.0 1.0 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions