Motif ID: STAT1_STAT3_BCL6

Z-value: 0.552

Transcription factors associated with STAT1_STAT3_BCL6:

Gene SymbolEntrez IDGene Name
BCL6 ENSG00000113916.13 BCL6
STAT1 ENSG00000115415.14 STAT1
STAT3 ENSG00000168610.10 STAT3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
STAT1hg19_v2_chr2_-_191878681_191878823-0.881.7e-03Click!
STAT3hg19_v2_chr17_-_40540377_40540481-0.809.9e-03Click!
BCL6hg19_v2_chr3_-_187454281_1874543570.255.2e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of STAT1_STAT3_BCL6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_93692781 1.672 ENST00000394236.3
PROS1
protein S (alpha)
chr17_-_26697304 0.819 ENST00000536498.1
VTN
vitronectin
chr19_+_47835404 0.659 ENST00000595464.1
C5AR2
complement component 5a receptor 2
chr9_-_134151915 0.630 ENST00000372271.3
FAM78A
family with sequence similarity 78, member A
chr7_-_87936195 0.617 ENST00000414498.1
ENST00000301959.5
ENST00000380079.4
STEAP4


STEAP family member 4


chr3_-_93692681 0.589 ENST00000348974.4
PROS1
protein S (alpha)
chr4_-_110723134 0.484 ENST00000510800.1
ENST00000512148.1
CFI

complement factor I

chr4_-_110723335 0.469 ENST00000394634.2
CFI
complement factor I
chr8_+_19759228 0.460 ENST00000520959.1
LPL
lipoprotein lipase
chr16_-_67517716 0.456 ENST00000290953.2
AGRP
agouti related protein homolog (mouse)
chr16_+_2198604 0.446 ENST00000210187.6
RAB26
RAB26, member RAS oncogene family
chr17_+_36858694 0.443 ENST00000563897.1
CTB-58E17.1
CTB-58E17.1
chr8_+_19796381 0.441 ENST00000524029.1
ENST00000522701.1
ENST00000311322.8
LPL


lipoprotein lipase


chr1_-_31845914 0.441 ENST00000373713.2
FABP3
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr2_-_190044480 0.438 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr4_-_110723194 0.428 ENST00000394635.3
CFI
complement factor I
chr10_-_90751038 0.426 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2


actin, alpha 2, smooth muscle, aorta


chr2_-_183291741 0.421 ENST00000351439.5
ENST00000409365.1
PDE1A

phosphodiesterase 1A, calmodulin-dependent

chr12_-_7244469 0.398 ENST00000538050.1
ENST00000536053.2
C1R

complement component 1, r subcomponent

chr12_+_58138664 0.364 ENST00000257910.3
TSPAN31
tetraspanin 31
chr16_-_46782221 0.358 ENST00000394809.4
MYLK3
myosin light chain kinase 3
chr16_+_14396121 0.355 ENST00000570945.1
RP11-65J21.3
RP11-65J21.3
chr1_-_68299130 0.355 ENST00000370982.3
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr7_-_74267836 0.341 ENST00000361071.5
ENST00000453619.2
ENST00000417115.2
ENST00000405086.2
GTF2IRD2



GTF2I repeat domain containing 2



chrX_-_154563889 0.331 ENST00000369449.2
ENST00000321926.4
CLIC2

chloride intracellular channel 2

chr11_-_8290263 0.330 ENST00000428101.2
LMO1
LIM domain only 1 (rhombotin 1)
chr7_+_74508372 0.328 ENST00000356115.5
ENST00000430511.2
ENST00000312575.7
GTF2IRD2B


GTF2I repeat domain containing 2B


chr7_-_138386097 0.327 ENST00000421622.1
SVOPL
SVOP-like
chr11_+_7618413 0.317 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr22_-_31536480 0.312 ENST00000215885.3
PLA2G3
phospholipase A2, group III
chr12_-_7261772 0.297 ENST00000545280.1
ENST00000543933.1
ENST00000545337.1
ENST00000544702.1
ENST00000266542.4
C1RL




complement component 1, r subcomponent-like




chr12_-_7245018 0.296 ENST00000543835.1
ENST00000535233.2
C1R

complement component 1, r subcomponent

chr12_+_53443963 0.291 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1


tensin like C1 domain containing phosphatase (tensin 2)


chr17_+_76311791 0.284 ENST00000586321.1
AC061992.2
AC061992.2
chr19_+_10196981 0.284 ENST00000591813.1
C19orf66
chromosome 19 open reading frame 66
chr22_+_31518938 0.283 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J






inositol polyphosphate-5-phosphatase J






chr11_-_115127611 0.276 ENST00000545094.1
CADM1
cell adhesion molecule 1
chr4_-_140477353 0.272 ENST00000406354.1
ENST00000506866.2
SETD7

SET domain containing (lysine methyltransferase) 7

chr10_-_62493223 0.271 ENST00000373827.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chrX_-_13835461 0.269 ENST00000316715.4
ENST00000356942.5
GPM6B

glycoprotein M6B

chr1_+_6845578 0.269 ENST00000467404.2
ENST00000439411.2
CAMTA1

calmodulin binding transcription activator 1

chr11_+_123986069 0.260 ENST00000456829.2
ENST00000361352.5
ENST00000449321.1
ENST00000392748.1
ENST00000360334.4
ENST00000392744.4
VWA5A





von Willebrand factor A domain containing 5A





chr2_-_84686552 0.257 ENST00000393868.2
SUCLG1
succinate-CoA ligase, alpha subunit
chr1_+_241695670 0.255 ENST00000366557.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr10_+_35484793 0.254 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM




cAMP responsive element modulator




chr9_-_89562104 0.250 ENST00000298743.7
GAS1
growth arrest-specific 1
chr1_+_6845497 0.243 ENST00000473578.1
ENST00000557126.1
CAMTA1

calmodulin binding transcription activator 1

chr7_+_134464414 0.241 ENST00000361901.2
CALD1
caldesmon 1
chr19_+_3708376 0.239 ENST00000539908.2
TJP3
tight junction protein 3
chr12_+_53443680 0.238 ENST00000314250.6
ENST00000451358.1
TENC1

tensin like C1 domain containing phosphatase (tensin 2)

chr8_+_93895865 0.233 ENST00000391681.1
AC117834.1
AC117834.1
chr12_+_58138800 0.232 ENST00000547992.1
ENST00000552816.1
ENST00000547472.1
TSPAN31


tetraspanin 31


chr17_+_2264983 0.230 ENST00000574650.1
SGSM2
small G protein signaling modulator 2
chr17_-_42994283 0.228 ENST00000593179.1
GFAP
glial fibrillary acidic protein
chr15_-_72462661 0.228 ENST00000570275.1
GRAMD2
GRAM domain containing 2
chr2_-_175499294 0.227 ENST00000392547.2
WIPF1
WAS/WASL interacting protein family, member 1
chr20_+_52105495 0.225 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr15_-_72462705 0.224 ENST00000564129.1
GRAMD2
GRAM domain containing 2
chr5_-_38845812 0.220 ENST00000513480.1
ENST00000512519.1
CTD-2127H9.1

CTD-2127H9.1

chr17_+_76356516 0.218 ENST00000592569.1
RP11-806H10.4
RP11-806H10.4
chr17_+_6347761 0.217 ENST00000250056.8
ENST00000571373.1
ENST00000570337.2
ENST00000572595.2
ENST00000576056.1
FAM64A




family with sequence similarity 64, member A




chr4_+_8594477 0.212 ENST00000315782.6
CPZ
carboxypeptidase Z
chr17_+_6347729 0.206 ENST00000572447.1
FAM64A
family with sequence similarity 64, member A
chr1_-_95846556 0.201 ENST00000426881.2
RP11-14O19.2
RP11-14O19.2
chr5_-_111092873 0.196 ENST00000509025.1
ENST00000515855.1
NREP

neuronal regeneration related protein

chr3_-_160117301 0.194 ENST00000326448.7
ENST00000498409.1
ENST00000475677.1
ENST00000478536.1
IFT80



intraflagellar transport 80 homolog (Chlamydomonas)



chr3_-_160116995 0.193 ENST00000465537.1
ENST00000486856.1
ENST00000468218.1
ENST00000478370.1
IFT80



intraflagellar transport 80 homolog (Chlamydomonas)



chr4_-_140005341 0.192 ENST00000379549.2
ENST00000512627.1
ELF2

E74-like factor 2 (ets domain transcription factor)

chr3_-_160117035 0.189 ENST00000489004.1
ENST00000496589.1
IFT80

intraflagellar transport 80 homolog (Chlamydomonas)

chr3_+_183894566 0.186 ENST00000439647.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr14_-_92414055 0.178 ENST00000342058.4
FBLN5
fibulin 5
chr11_+_73003824 0.177 ENST00000538328.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr18_+_32173276 0.176 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA








dystrobrevin, alpha








chr5_+_135383008 0.176 ENST00000508767.1
ENST00000604555.1
TGFBI

transforming growth factor, beta-induced, 68kDa

chr3_-_52864680 0.175 ENST00000406595.1
ENST00000485816.1
ENST00000434759.3
ENST00000346281.5
ENST00000266041.4
ITIH4




inter-alpha-trypsin inhibitor heavy chain family, member 4




chr10_-_25010795 0.172 ENST00000416305.1
ENST00000376410.2
ARHGAP21

Rho GTPase activating protein 21

chr11_-_36310958 0.171 ENST00000532705.1
ENST00000263401.5
ENST00000452374.2
COMMD9


COMM domain containing 9


chr18_+_21464737 0.171 ENST00000586751.1
LAMA3
laminin, alpha 3
chr3_+_122399444 0.169 ENST00000474629.2
PARP14
poly (ADP-ribose) polymerase family, member 14
chr15_-_72462384 0.169 ENST00000568594.1
GRAMD2
GRAM domain containing 2
chr11_+_62652649 0.168 ENST00000539507.1
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr3_-_149095652 0.168 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr11_+_57365150 0.167 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1




serpin peptidase inhibitor, clade G (C1 inhibitor), member 1




chr5_-_121413974 0.167 ENST00000231004.4
LOX
lysyl oxidase
chr11_-_111782696 0.166 ENST00000227251.3
ENST00000526180.1
CRYAB

crystallin, alpha B

chr8_-_82645082 0.166 ENST00000523361.1
ZFAND1
zinc finger, AN1-type domain 1
chrX_+_77154935 0.163 ENST00000481445.1
COX7B
cytochrome c oxidase subunit VIIb
chr5_-_34043310 0.162 ENST00000231338.7
C1QTNF3
C1q and tumor necrosis factor related protein 3
chr5_+_43603229 0.161 ENST00000344920.4
ENST00000512996.2
NNT

nicotinamide nucleotide transhydrogenase

chr15_-_50411412 0.159 ENST00000284509.6
ATP8B4
ATPase, class I, type 8B, member 4
chr20_-_43280361 0.159 ENST00000372874.4
ADA
adenosine deaminase
chr1_-_241803679 0.158 ENST00000331838.5
OPN3
opsin 3
chr8_-_22089533 0.158 ENST00000321613.3
PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr17_-_79917645 0.156 ENST00000477214.1
NOTUM
notum pectinacetylesterase homolog (Drosophila)
chr11_-_111649015 0.156 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr8_-_22089845 0.154 ENST00000454243.2
PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chrX_-_115594160 0.150 ENST00000371894.4
CXorf61
cancer/testis antigen 83
chr12_-_11175219 0.149 ENST00000390673.2
TAS2R19
taste receptor, type 2, member 19
chr1_+_26485511 0.148 ENST00000374268.3
FAM110D
family with sequence similarity 110, member D
chr3_+_185000729 0.146 ENST00000448876.1
ENST00000446828.1
ENST00000447637.1
ENST00000424227.1
ENST00000454237.1
MAP3K13




mitogen-activated protein kinase kinase kinase 13




chr5_-_111093167 0.145 ENST00000446294.2
ENST00000419114.2
NREP

neuronal regeneration related protein

chr11_-_111649074 0.145 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr3_+_122399697 0.143 ENST00000494811.1
PARP14
poly (ADP-ribose) polymerase family, member 14
chr6_+_31730773 0.142 ENST00000415669.2
ENST00000425424.1
SAPCD1

suppressor APC domain containing 1

chr1_-_241803649 0.142 ENST00000366554.2
OPN3
opsin 3
chr5_-_111093081 0.141 ENST00000453526.2
ENST00000509427.1
NREP

neuronal regeneration related protein

chr1_+_182584314 0.140 ENST00000566297.1
RP11-317P15.4
RP11-317P15.4
chr3_+_108321623 0.140 ENST00000497905.1
ENST00000463306.1
DZIP3

DAZ interacting zinc finger protein 3

chr6_+_26104104 0.140 ENST00000377803.2
HIST1H4C
histone cluster 1, H4c
chr22_+_24990746 0.138 ENST00000456869.1
ENST00000411974.1
GGT1

gamma-glutamyltransferase 1

chr22_-_50699701 0.137 ENST00000395780.1
MAPK12
mitogen-activated protein kinase 12
chr11_+_112041253 0.136 ENST00000532612.1
AP002884.3
AP002884.3
chr1_-_153521597 0.133 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chr4_-_140005443 0.133 ENST00000510408.1
ENST00000420916.2
ENST00000358635.3
ELF2


E74-like factor 2 (ets domain transcription factor)


chr14_+_76452090 0.131 ENST00000314067.6
ENST00000238628.6
ENST00000556742.1
IFT43


intraflagellar transport 43 homolog (Chlamydomonas)


chr21_+_17102311 0.130 ENST00000285679.6
ENST00000351097.5
ENST00000285681.2
ENST00000400183.2
USP25



ubiquitin specific peptidase 25



chrX_+_123095546 0.130 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
STAG2


stromal antigen 2


chr9_-_139891165 0.129 ENST00000494426.1
CLIC3
chloride intracellular channel 3
chr19_+_49977818 0.129 ENST00000594009.1
ENST00000595510.1
FLT3LG

fms-related tyrosine kinase 3 ligand

chr5_-_111092930 0.127 ENST00000257435.7
NREP
neuronal regeneration related protein
chr8_-_97247759 0.126 ENST00000518406.1
ENST00000523920.1
ENST00000287022.5
UQCRB


ubiquinol-cytochrome c reductase binding protein


chr5_-_22853429 0.126 ENST00000504376.2
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr7_+_75511362 0.125 ENST00000428119.1
RHBDD2
rhomboid domain containing 2
chr9_-_4741255 0.124 ENST00000381809.3
AK3
adenylate kinase 3
chr1_+_6845384 0.124 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr14_+_72064945 0.121 ENST00000537413.1
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr2_-_15701422 0.121 ENST00000441750.1
ENST00000281513.5
NBAS

neuroblastoma amplified sequence

chr12_-_57410304 0.121 ENST00000441881.1
ENST00000458521.2
TAC3

tachykinin 3

chr7_+_135611542 0.120 ENST00000416501.1
AC015987.2
AC015987.2
chr2_-_175547571 0.118 ENST00000409415.3
ENST00000359761.3
ENST00000272746.5
WIPF1


WAS/WASL interacting protein family, member 1


chr8_-_102803163 0.118 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD






neurocalcin delta






chr14_-_76447494 0.118 ENST00000238682.3
TGFB3
transforming growth factor, beta 3
chr1_+_155278539 0.117 ENST00000447866.1
FDPS
farnesyl diphosphate synthase
chr1_-_212004090 0.117 ENST00000366997.4
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr17_-_76124711 0.116 ENST00000306591.7
ENST00000590602.1
TMC6

transmembrane channel-like 6

chr12_-_56727676 0.115 ENST00000547572.1
ENST00000257931.5
ENST00000440411.3
PAN2


PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)


chr5_+_150639360 0.115 ENST00000523004.1
GM2A
GM2 ganglioside activator
chr5_-_111093406 0.115 ENST00000379671.3
NREP
neuronal regeneration related protein
chr19_+_35168547 0.115 ENST00000502743.1
ENST00000509528.1
ENST00000506901.1
ZNF302


zinc finger protein 302


chr1_+_229440129 0.114 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr6_-_136788001 0.114 ENST00000544465.1
MAP7
microtubule-associated protein 7
chr6_+_110012462 0.112 ENST00000441478.2
ENST00000230124.3
FIG4

FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)

chr5_+_93954039 0.112 ENST00000265140.5
ANKRD32
ankyrin repeat domain 32
chr1_+_155278625 0.111 ENST00000368356.4
ENST00000356657.6
FDPS

farnesyl diphosphate synthase

chr11_+_73000449 0.109 ENST00000535931.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr17_+_5323492 0.109 ENST00000405578.4
ENST00000574003.1
RPAIN

RPA interacting protein

chr11_-_102668879 0.108 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr10_+_115511434 0.108 ENST00000369312.4
PLEKHS1
pleckstrin homology domain containing, family S member 1
chr1_+_59250815 0.108 ENST00000544621.1
ENST00000419531.2
RP4-794H19.2

long intergenic non-protein coding RNA 1135

chrX_+_123095155 0.107 ENST00000371160.1
ENST00000435103.1
STAG2

stromal antigen 2

chr3_+_46283863 0.107 ENST00000545097.1
ENST00000541018.1
CCR3

chemokine (C-C motif) receptor 3

chr6_+_149068464 0.107 ENST00000367463.4
UST
uronyl-2-sulfotransferase
chr16_-_10652993 0.106 ENST00000536829.1
EMP2
epithelial membrane protein 2
chr17_+_74729060 0.105 ENST00000587459.1
RP11-318A15.7
Uncharacterized protein
chr18_+_66382428 0.105 ENST00000578970.1
ENST00000582371.1
ENST00000584775.1
CCDC102B


coiled-coil domain containing 102B


chr16_-_8955601 0.104 ENST00000569398.1
ENST00000568968.1
CARHSP1

calcium regulated heat stable protein 1, 24kDa

chr17_+_79761997 0.104 ENST00000400723.3
ENST00000570996.1
GCGR

glucagon receptor

chr8_-_18666360 0.103 ENST00000286485.8
PSD3
pleckstrin and Sec7 domain containing 3
chr19_+_44669221 0.103 ENST00000590578.1
ENST00000589160.1
ENST00000337433.5
ENST00000586286.1
ENST00000585560.1
ENST00000586914.1
ENST00000588883.1
ENST00000413984.2
ENST00000588742.1
ENST00000300823.6
ENST00000585678.1
ENST00000586203.1
ENST00000590467.1
ENST00000588795.1
ENST00000588127.1
ZNF226














zinc finger protein 226














chr12_-_88974236 0.102 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG


KIT ligand


chr5_-_151066514 0.102 ENST00000538026.1
ENST00000522348.1
ENST00000521569.1
SPARC


secreted protein, acidic, cysteine-rich (osteonectin)


chr5_+_93954358 0.101 ENST00000504099.1
ANKRD32
ankyrin repeat domain 32
chr12_+_56477093 0.100 ENST00000549672.1
ENST00000415288.2
ERBB3

v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3

chr9_-_4741217 0.100 ENST00000447596.4
AK3
adenylate kinase 3
chr4_-_185694872 0.099 ENST00000505492.1
ACSL1
acyl-CoA synthetase long-chain family member 1
chr1_-_41328018 0.099 ENST00000372638.2
CITED4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr8_-_71157595 0.099 ENST00000519724.1
NCOA2
nuclear receptor coactivator 2
chrX_+_123095890 0.099 ENST00000435215.1
STAG2
stromal antigen 2
chr12_-_56727487 0.097 ENST00000548043.1
ENST00000425394.2
PAN2

PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)

chr5_-_111093340 0.097 ENST00000508870.1
NREP
neuronal regeneration related protein
chr4_+_86396265 0.097 ENST00000395184.1
ARHGAP24
Rho GTPase activating protein 24
chr15_+_44719394 0.096 ENST00000260327.4
ENST00000396780.1
CTDSPL2

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2

chr8_-_95274536 0.096 ENST00000297596.2
ENST00000396194.2
GEM

GTP binding protein overexpressed in skeletal muscle

chr19_+_17530838 0.096 ENST00000528659.1
ENST00000392702.2
ENST00000529939.1
MVB12A


multivesicular body subunit 12A


chr3_-_187455680 0.096 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chr16_-_67260901 0.095 ENST00000341546.3
ENST00000409509.1
ENST00000433915.1
ENST00000454102.2
LRRC29


AC040160.1
leucine rich repeat containing 29


Uncharacterized protein; cDNA FLJ57407, weakly similar to Mus musculus leucine rich repeat containing 29 (Lrrc29), mRNA
chr1_-_156265438 0.095 ENST00000362007.1
C1orf85
chromosome 1 open reading frame 85
chr16_-_70323422 0.095 ENST00000261772.8
AARS
alanyl-tRNA synthetase
chrX_+_123095860 0.095 ENST00000428941.1
STAG2
stromal antigen 2
chr1_+_6511651 0.094 ENST00000434576.1
ESPN
espin
chr19_-_4902877 0.093 ENST00000381781.2
ARRDC5
arrestin domain containing 5
chr1_+_190448095 0.093 ENST00000424735.1
RP11-547I7.2
RP11-547I7.2
chr19_+_15783879 0.093 ENST00000551607.1
CYP4F12
cytochrome P450, family 4, subfamily F, polypeptide 12
chr2_-_166651152 0.092 ENST00000431484.1
ENST00000412248.1
GALNT3

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)

chr4_+_86396321 0.092 ENST00000503995.1
ARHGAP24
Rho GTPase activating protein 24
chr9_-_5830768 0.092 ENST00000381506.3
ERMP1
endoplasmic reticulum metallopeptidase 1
chrX_+_102631248 0.091 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
NGFRAP1


nerve growth factor receptor (TNFRSF16) associated protein 1


chr22_-_39637135 0.091 ENST00000440375.1
PDGFB
platelet-derived growth factor beta polypeptide
chr18_-_10748498 0.090 ENST00000579949.1
PIEZO2
piezo-type mechanosensitive ion channel component 2
chr6_-_110011718 0.090 ENST00000532976.1
AK9
adenylate kinase 9
chr9_+_124088860 0.089 ENST00000373806.1
GSN
gelsolin
chr17_-_2304365 0.089 ENST00000575394.1
ENST00000174618.4
MNT

MAX network transcriptional repressor

chr2_-_166651191 0.088 ENST00000392701.3
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr19_+_44764031 0.087 ENST00000592581.1
ENST00000590668.1
ENST00000588489.1
ENST00000391958.2
ZNF233



zinc finger protein 233



chr1_-_155006224 0.087 ENST00000368424.3
DCST2
DC-STAMP domain containing 2
chr4_-_89978299 0.087 ENST00000511976.1
ENST00000509094.1
ENST00000264344.5
ENST00000515600.1
FAM13A



family with sequence similarity 13, member A



chr9_-_21335240 0.087 ENST00000537938.1
KLHL9
kelch-like family member 9
chr16_+_69221028 0.086 ENST00000336278.4
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr17_-_27038063 0.086 ENST00000439862.3
PROCA1
protein interacting with cyclin A1
chr5_+_32531893 0.085 ENST00000512913.1
SUB1
SUB1 homolog (S. cerevisiae)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.1 0.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 2.3 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.9 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.4 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1 0.6 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.2 GO:0046041 ITP metabolic process(GO:0046041)
0.1 0.4 GO:0060298 regulation of vascular permeability involved in acute inflammatory response(GO:0002528) positive regulation of sarcomere organization(GO:0060298)
0.1 0.4 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.2 GO:0006174 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.1 0.2 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.1 0.2 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.1 0.3 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.2 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.1 0.2 GO:1990697 protein depalmitoleylation(GO:1990697)
0.1 0.2 GO:0003032 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.1 0.5 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.3 GO:0071865 regulation of apoptotic process in bone marrow(GO:0071865) negative regulation of apoptotic process in bone marrow(GO:0071866)
0.0 0.2 GO:0033384 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.0 0.3 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.8 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0072255 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.0 0.1 GO:0051685 maintenance of ER location(GO:0051685)
0.0 0.3 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.1 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0 0.1 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.3 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.1 GO:0003095 pressure natriuresis(GO:0003095)
0.0 0.1 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.4 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.3 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:1903410 renin-angiotensin regulation of aldosterone production(GO:0002018) regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.0 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.1 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:0060356 leucine import(GO:0060356)
0.0 0.1 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.2 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.3 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0019075 virus maturation(GO:0019075)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:1990641 cellular response to bile acid(GO:1903413) negative regulation of intestinal absorption(GO:1904479) response to iron ion starvation(GO:1990641)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.3 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.2 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.1 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.0 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.0 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.1 GO:0006844 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
0.0 0.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.0 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.2 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.1 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.7 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.3 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.2 GO:0031251 PAN complex(GO:0031251)
0.0 0.9 GO:0042627 chylomicron(GO:0042627)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.2 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 3.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0017129 triglyceride binding(GO:0017129)
0.2 0.7 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.1 0.4 GO:0070538 oleic acid binding(GO:0070538)
0.1 0.6 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.4 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.2 GO:0042007 interleukin-18 binding(GO:0042007)
0.1 0.2 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.2 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.1 0.3 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.2 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.3 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.7 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.3 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.3 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226) acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.0 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
0.0 0.1 GO:0004797 thymidine kinase activity(GO:0004797)
0.0 2.6 GO:0004866 endopeptidase inhibitor activity(GO:0004866)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.4 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.0 0.8 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME_OPSINS Genes involved in Opsins
0.0 0.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.0 0.6 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta