Motif ID: SREBF1_TFE3

Z-value: 0.761

Transcription factors associated with SREBF1_TFE3:

Gene SymbolEntrez IDGene Name
SREBF1 ENSG00000072310.12 SREBF1
TFE3 ENSG00000068323.12 TFE3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SREBF1hg19_v2_chr17_-_17726907_177269580.809.1e-03Click!
TFE3hg19_v2_chrX_-_48901012_48901050-0.058.9e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of SREBF1_TFE3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_1785139 1.556 ENST00000236671.2
CTSD
cathepsin D
chr17_-_7137582 1.441 ENST00000575756.1
ENST00000575458.1
DVL2

dishevelled segment polarity protein 2

chr12_-_58145889 1.266 ENST00000547853.1
CDK4
cyclin-dependent kinase 4
chr16_+_2570340 1.245 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
AMDHD2





amidohydrolase domain containing 2





chr17_-_7137857 1.232 ENST00000005340.5
DVL2
dishevelled segment polarity protein 2
chr4_+_111397216 1.039 ENST00000265162.5
ENPEP
glutamyl aminopeptidase (aminopeptidase A)
chr19_+_1275917 0.934 ENST00000469144.1
C19orf24
chromosome 19 open reading frame 24
chr17_+_42422662 0.920 ENST00000593167.1
ENST00000585512.1
ENST00000591740.1
ENST00000592783.1
ENST00000587387.1
ENST00000588237.1
ENST00000589265.1
GRN






granulin






chr17_+_42422629 0.839 ENST00000589536.1
ENST00000587109.1
ENST00000587518.1
GRN


granulin


chr16_-_5083917 0.794 ENST00000312251.3
ENST00000381955.3
NAGPA

N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase

chr16_+_28986134 0.773 ENST00000352260.7
SPNS1
spinster homolog 1 (Drosophila)
chr17_+_62223320 0.760 ENST00000580828.1
ENST00000582965.1
SNORA76

small nucleolar RNA, H/ACA box 76

chr16_+_28986085 0.752 ENST00000565975.1
ENST00000311008.11
ENST00000323081.8
ENST00000334536.8
SPNS1



spinster homolog 1 (Drosophila)



chr19_+_5681153 0.736 ENST00000577222.1
ENST00000579559.1
RPL36
HSD11B1L
ribosomal protein L36
hydroxysteroid (11-beta) dehydrogenase 1-like
chr12_+_123849462 0.727 ENST00000543072.1
hsa-mir-8072
hsa-mir-8072
chr16_-_30134524 0.699 ENST00000395202.1
ENST00000395199.3
ENST00000263025.4
ENST00000322266.5
ENST00000403394.1
MAPK3




mitogen-activated protein kinase 3




chr5_-_121413974 0.681 ENST00000231004.4
LOX
lysyl oxidase
chr17_+_42422637 0.666 ENST00000053867.3
ENST00000588143.1
GRN

granulin

chr16_+_2570431 0.658 ENST00000563556.1
AMDHD2
amidohydrolase domain containing 2
chr16_-_5083589 0.655 ENST00000563578.1
ENST00000562346.2
NAGPA

N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase

chr17_+_6915730 0.649 ENST00000548577.1
RNASEK
ribonuclease, RNase K
chr15_+_44084040 0.646 ENST00000249786.4
SERF2
small EDRK-rich factor 2
chr17_+_6915798 0.634 ENST00000402093.1
RNASEK
ribonuclease, RNase K
chr19_-_5680891 0.626 ENST00000309324.4
C19orf70
chromosome 19 open reading frame 70
chr11_+_67159416 0.618 ENST00000307980.2
ENST00000544620.1
RAD9A

RAD9 homolog A (S. pombe)

chr2_+_176972000 0.597 ENST00000249504.5
HOXD11
homeobox D11
chr16_-_1525016 0.576 ENST00000262318.8
ENST00000448525.1
CLCN7

chloride channel, voltage-sensitive 7

chr7_+_4815238 0.571 ENST00000348624.4
ENST00000401897.1
AP5Z1

adaptor-related protein complex 5, zeta 1 subunit

chr19_+_8386371 0.565 ENST00000600659.2
RPS28
ribosomal protein S28
chr16_-_30134441 0.558 ENST00000395200.1
MAPK3
mitogen-activated protein kinase 3
chr20_+_44520009 0.533 ENST00000607482.1
ENST00000372459.2
CTSA

cathepsin A

chr20_+_44519948 0.529 ENST00000354880.5
ENST00000191018.5
CTSA

cathepsin A

chr17_+_78075498 0.518 ENST00000302262.3
GAA
glucosidase, alpha; acid
chr13_+_113951607 0.518 ENST00000397181.3
LAMP1
lysosomal-associated membrane protein 1
chr11_+_61560348 0.505 ENST00000574708.1
ENST00000535723.1
FADS2
FEN1
fatty acid desaturase 2
flap structure-specific endonuclease 1
chr1_-_11866034 0.468 ENST00000376590.3
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr10_+_102759045 0.466 ENST00000370220.1
LZTS2
leucine zipper, putative tumor suppressor 2
chr5_-_176730676 0.463 ENST00000393611.2
ENST00000303251.6
ENST00000303270.6
RAB24


RAB24, member RAS oncogene family


chr17_+_6915902 0.460 ENST00000570898.1
ENST00000552842.1
RNASEK

ribonuclease, RNase K

chr16_-_28503327 0.457 ENST00000535392.1
ENST00000395653.4
CLN3

ceroid-lipofuscinosis, neuronal 3

chr19_+_49458107 0.453 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
BAX






BCL2-associated X protein






chr20_-_36156264 0.453 ENST00000445723.1
ENST00000414080.1
BLCAP

bladder cancer associated protein

chr16_-_28503357 0.451 ENST00000333496.9
ENST00000561505.1
ENST00000567963.1
ENST00000354630.5
ENST00000355477.5
ENST00000357076.5
ENST00000565688.1
ENST00000359984.7
CLN3







ceroid-lipofuscinosis, neuronal 3







chr19_+_40854559 0.437 ENST00000598962.1
ENST00000409419.1
ENST00000409587.1
ENST00000602131.1
ENST00000409735.4
ENST00000600948.1
ENST00000356508.5
ENST00000596682.1
ENST00000594908.1
PLD3








phospholipase D family, member 3








chr16_-_28503080 0.436 ENST00000565316.1
ENST00000565778.1
ENST00000357857.9
ENST00000568558.1
ENST00000357806.7
CLN3




ceroid-lipofuscinosis, neuronal 3




chr17_-_76124812 0.434 ENST00000592063.1
ENST00000589271.1
ENST00000322933.4
ENST00000589553.1
TMC6



transmembrane channel-like 6



chr17_+_78075361 0.430 ENST00000577106.1
ENST00000390015.3
GAA

glucosidase, alpha; acid

chr1_-_11865982 0.424 ENST00000418034.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr19_-_15236173 0.416 ENST00000527093.1
ILVBL
ilvB (bacterial acetolactate synthase)-like
chr3_+_127317705 0.408 ENST00000480910.1
MCM2
minichromosome maintenance complex component 2
chr20_-_2821271 0.404 ENST00000448755.1
ENST00000360652.2
PCED1A

PC-esterase domain containing 1A

chr3_-_49395892 0.397 ENST00000419783.1
GPX1
glutathione peroxidase 1
chr19_+_40873617 0.396 ENST00000599353.1
PLD3
phospholipase D family, member 3
chr3_-_49395705 0.395 ENST00000419349.1
GPX1
glutathione peroxidase 1
chr15_+_44084503 0.393 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
SERF2







small EDRK-rich factor 2







chr16_+_19467772 0.390 ENST00000219821.5
ENST00000561503.1
ENST00000564959.1
TMC5


transmembrane channel-like 5


chr5_+_52776449 0.388 ENST00000396947.3
FST
follistatin
chr5_+_52776228 0.384 ENST00000256759.3
FST
follistatin
chr16_-_30134266 0.381 ENST00000484663.1
ENST00000478356.1
MAPK3

mitogen-activated protein kinase 3

chr20_-_2821756 0.380 ENST00000356872.3
ENST00000439542.1
PCED1A

PC-esterase domain containing 1A

chr19_+_7587491 0.378 ENST00000264079.6
MCOLN1
mucolipin 1
chr19_+_7587555 0.376 ENST00000601003.1
MCOLN1
mucolipin 1
chr7_+_916183 0.369 ENST00000265857.3
GET4
golgi to ER traffic protein 4 homolog (S. cerevisiae)
chr1_-_154928562 0.367 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
PBXIP1




pre-B-cell leukemia homeobox interacting protein 1




chr22_-_39636914 0.367 ENST00000381551.4
PDGFB
platelet-derived growth factor beta polypeptide
chr16_-_1401799 0.367 ENST00000007390.2
TSR3
TSR3, 20S rRNA accumulation, homolog (S. cerevisiae)
chr1_+_11796126 0.358 ENST00000376637.3
AGTRAP
angiotensin II receptor-associated protein
chr16_-_2097787 0.358 ENST00000566380.1
ENST00000219066.1
NTHL1

nth endonuclease III-like 1 (E. coli)

chr1_+_11796177 0.349 ENST00000400895.2
ENST00000376629.4
ENST00000376627.2
ENST00000314340.5
ENST00000452018.2
ENST00000510878.1
AGTRAP





angiotensin II receptor-associated protein





chr14_+_105941118 0.347 ENST00000550577.1
ENST00000538259.2
CRIP2

cysteine-rich protein 2

chr10_+_102756800 0.344 ENST00000370223.3
LZTS2
leucine zipper, putative tumor suppressor 2
chr11_+_118938485 0.340 ENST00000300793.6
VPS11
vacuolar protein sorting 11 homolog (S. cerevisiae)
chr17_-_76124711 0.338 ENST00000306591.7
ENST00000590602.1
TMC6

transmembrane channel-like 6

chr5_-_176730733 0.338 ENST00000504395.1
RAB24
RAB24, member RAS oncogene family
chr11_-_61560254 0.335 ENST00000543510.1
TMEM258
transmembrane protein 258
chr11_-_61560053 0.334 ENST00000537328.1
TMEM258
transmembrane protein 258
chr17_-_79791118 0.333 ENST00000576431.1
ENST00000575061.1
ENST00000455127.2
ENST00000572645.1
ENST00000538396.1
ENST00000573478.1
FAM195B





family with sequence similarity 195, member B





chr4_-_186733363 0.332 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2


sorbin and SH3 domain containing 2


chr15_-_72668805 0.326 ENST00000268097.5
HEXA
hexosaminidase A (alpha polypeptide)
chr9_-_21995249 0.325 ENST00000494262.1
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr1_-_31845914 0.322 ENST00000373713.2
FABP3
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr18_+_44497455 0.322 ENST00000592005.1
KATNAL2
katanin p60 subunit A-like 2
chr17_+_1627834 0.322 ENST00000419248.1
ENST00000418841.1
WDR81

WD repeat domain 81

chr19_-_36545649 0.320 ENST00000292894.1
THAP8
THAP domain containing 8
chr17_+_57408994 0.320 ENST00000312655.4
YPEL2
yippee-like 2 (Drosophila)
chr7_+_100271446 0.317 ENST00000419828.1
ENST00000427895.1
GNB2

guanine nucleotide binding protein (G protein), beta polypeptide 2

chr19_+_10812108 0.312 ENST00000250237.5
ENST00000592254.1
QTRT1

queuine tRNA-ribosyltransferase 1

chr17_+_37356555 0.312 ENST00000579374.1
RPL19
ribosomal protein L19
chr19_-_5720248 0.310 ENST00000360614.3
LONP1
lon peptidase 1, mitochondrial
chr7_+_100271355 0.309 ENST00000436220.1
ENST00000424361.1
GNB2

guanine nucleotide binding protein (G protein), beta polypeptide 2

chr22_+_35695793 0.305 ENST00000456128.1
ENST00000449058.2
ENST00000411850.1
ENST00000425375.1
ENST00000436462.2
ENST00000382034.5
TOM1





target of myb1 (chicken)





chr6_-_33385854 0.305 ENST00000488478.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr17_+_37356528 0.302 ENST00000225430.4
RPL19
ribosomal protein L19
chr5_+_34656331 0.300 ENST00000265109.3
RAI14
retinoic acid induced 14
chr12_-_109027643 0.300 ENST00000388962.3
ENST00000550948.1
SELPLG

selectin P ligand

chr10_+_99258625 0.299 ENST00000370664.3
UBTD1
ubiquitin domain containing 1
chr17_+_37356586 0.299 ENST00000579260.1
ENST00000582193.1
RPL19

ribosomal protein L19

chr17_+_73975292 0.295 ENST00000397640.1
ENST00000416485.1
ENST00000588202.1
ENST00000590676.1
ENST00000586891.1
TEN1




TEN1 CST complex subunit




chr16_-_88923285 0.295 ENST00000542788.1
ENST00000569433.1
ENST00000268695.5
ENST00000568311.1
GALNS



galactosamine (N-acetyl)-6-sulfate sulfatase



chr19_-_15236470 0.295 ENST00000533747.1
ENST00000598709.1
ENST00000534378.1
ILVBL


ilvB (bacterial acetolactate synthase)-like


chr19_-_3600549 0.294 ENST00000589966.1
TBXA2R
thromboxane A2 receptor
chr3_-_112280709 0.289 ENST00000402314.2
ENST00000283290.5
ENST00000492886.1
ATG3


autophagy related 3


chr1_-_156265438 0.284 ENST00000362007.1
C1orf85
chromosome 1 open reading frame 85
chr2_-_220042825 0.282 ENST00000409789.1
CNPPD1
cyclin Pas1/PHO80 domain containing 1
chr19_-_3985455 0.276 ENST00000309311.6
EEF2
eukaryotic translation elongation factor 2
chr19_-_1237990 0.274 ENST00000382477.2
ENST00000215376.6
ENST00000590083.1
C19orf26


chromosome 19 open reading frame 26


chr5_+_34656529 0.274 ENST00000513974.1
ENST00000512629.1
RAI14

retinoic acid induced 14

chr16_+_1401924 0.273 ENST00000204679.4
ENST00000529110.1
GNPTG

N-acetylglucosamine-1-phosphate transferase, gamma subunit

chr5_+_34656450 0.273 ENST00000514527.1
RAI14
retinoic acid induced 14
chr11_-_66336060 0.270 ENST00000310325.5
CTSF
cathepsin F
chr22_-_20850128 0.263 ENST00000328879.4
KLHL22
kelch-like family member 22
chr6_-_33385823 0.262 ENST00000494751.1
ENST00000374496.3
CUTA

cutA divalent cation tolerance homolog (E. coli)

chr3_+_112280857 0.261 ENST00000492406.1
ENST00000468642.1
SLC35A5

solute carrier family 35, member A5

chr6_-_43197189 0.259 ENST00000509253.1
ENST00000393987.2
ENST00000230431.6
DNPH1


2'-deoxynucleoside 5'-phosphate N-hydrolase 1


chr19_-_15236562 0.259 ENST00000263383.3
ILVBL
ilvB (bacterial acetolactate synthase)-like
chr19_+_49990811 0.257 ENST00000391857.4
ENST00000467825.2
RPL13A

ribosomal protein L13a

chr1_-_209825674 0.255 ENST00000367030.3
ENST00000356082.4
LAMB3

laminin, beta 3

chr8_-_145688231 0.255 ENST00000530374.1
CYHR1
cysteine/histidine-rich 1
chrX_+_153657009 0.254 ENST00000449556.1
ATP6AP1
ATPase, H+ transporting, lysosomal accessory protein 1
chr7_+_99746514 0.250 ENST00000341942.5
ENST00000441173.1
LAMTOR4

late endosomal/lysosomal adaptor, MAPK and MTOR activator 4

chrX_-_13835461 0.247 ENST00000316715.4
ENST00000356942.5
GPM6B

glycoprotein M6B

chr3_+_51428704 0.243 ENST00000323686.4
RBM15B
RNA binding motif protein 15B
chr6_-_33385870 0.243 ENST00000488034.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr19_-_5720123 0.242 ENST00000587365.1
ENST00000585374.1
ENST00000593119.1
LONP1


lon peptidase 1, mitochondrial


chr22_-_42342692 0.241 ENST00000404067.1
ENST00000402338.1
CENPM

centromere protein M

chr7_-_150777920 0.240 ENST00000353841.2
ENST00000297532.6
FASTK

Fas-activated serine/threonine kinase

chr19_-_40854281 0.238 ENST00000392035.2
C19orf47
chromosome 19 open reading frame 47
chr19_-_5680499 0.237 ENST00000587589.1
C19orf70
chromosome 19 open reading frame 70
chr9_-_21995300 0.237 ENST00000498628.2
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr7_+_106810165 0.236 ENST00000468401.1
ENST00000497535.1
ENST00000485846.1
HBP1


HMG-box transcription factor 1


chr3_-_98312548 0.236 ENST00000264193.2
CPOX
coproporphyrinogen oxidase
chr19_-_5719860 0.231 ENST00000590729.1
LONP1
lon peptidase 1, mitochondrial
chr17_+_79935418 0.228 ENST00000306729.7
ENST00000306739.4
ASPSCR1

alveolar soft part sarcoma chromosome region, candidate 1

chr16_+_699319 0.227 ENST00000549091.1
ENST00000293879.4
WDR90

WD repeat domain 90

chr1_+_221051699 0.226 ENST00000366903.6
HLX
H2.0-like homeobox
chr7_-_150777949 0.225 ENST00000482571.1
FASTK
Fas-activated serine/threonine kinase
chr19_+_40854363 0.224 ENST00000599685.1
ENST00000392032.2
PLD3

phospholipase D family, member 3

chr17_+_78152274 0.222 ENST00000344227.2
ENST00000570421.1
CARD14

caspase recruitment domain family, member 14

chr19_-_8386238 0.221 ENST00000301457.2
NDUFA7
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
chr13_+_113951532 0.221 ENST00000332556.4
LAMP1
lysosomal-associated membrane protein 1
chr19_-_11545920 0.218 ENST00000356392.4
ENST00000591179.1
CCDC151

coiled-coil domain containing 151

chr6_-_33385655 0.217 ENST00000440279.3
ENST00000607266.1
CUTA

cutA divalent cation tolerance homolog (E. coli)

chr17_-_73851285 0.217 ENST00000589642.1
ENST00000593002.1
ENST00000590221.1
ENST00000344296.4
ENST00000587374.1
ENST00000585462.1
ENST00000433525.2
ENST00000254806.3
WBP2







WW domain binding protein 2







chr17_+_40688190 0.216 ENST00000225927.2
NAGLU
N-acetylglucosaminidase, alpha
chr12_-_114211444 0.216 ENST00000510694.2
ENST00000550223.1
RP11-438N16.1

RP11-438N16.1

chr11_-_71814422 0.215 ENST00000278671.5
LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr2_+_242673994 0.212 ENST00000321264.4
ENST00000537090.1
ENST00000403782.1
ENST00000342518.6
D2HGDH



D-2-hydroxyglutarate dehydrogenase



chr5_-_1799932 0.212 ENST00000382647.7
ENST00000505059.2
MRPL36

mitochondrial ribosomal protein L36

chr9_+_133320301 0.206 ENST00000352480.5
ASS1
argininosuccinate synthase 1
chr4_-_75024085 0.205 ENST00000600169.1
AC093677.1
Uncharacterized protein
chr6_-_33385902 0.202 ENST00000374500.5
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr11_-_327537 0.202 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chr3_+_113465866 0.202 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATP6V1A



ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A



chr1_+_154975110 0.202 ENST00000535420.1
ENST00000368426.3
ZBTB7B

zinc finger and BTB domain containing 7B

chr11_-_61101247 0.201 ENST00000543627.1
DDB1
damage-specific DNA binding protein 1, 127kDa
chr5_+_34656569 0.201 ENST00000428746.2
RAI14
retinoic acid induced 14
chr19_-_12886327 0.200 ENST00000397668.3
ENST00000587178.1
ENST00000264827.5
HOOK2


hook microtubule-tethering protein 2


chr11_+_62538775 0.199 ENST00000294168.3
ENST00000526261.1
TAF6L

TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa

chr17_-_6915646 0.199 ENST00000574377.1
ENST00000399541.2
ENST00000399540.2
ENST00000575727.1
ENST00000573939.1
AC027763.2




Uncharacterized protein




chr17_-_18266818 0.196 ENST00000583780.1
SHMT1
serine hydroxymethyltransferase 1 (soluble)
chr3_-_113465065 0.196 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
NAA50



N(alpha)-acetyltransferase 50, NatE catalytic subunit



chr11_-_61684962 0.195 ENST00000394836.2
RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr11_-_36310958 0.193 ENST00000532705.1
ENST00000263401.5
ENST00000452374.2
COMMD9


COMM domain containing 9


chr19_+_46009837 0.192 ENST00000589627.1
VASP
vasodilator-stimulated phosphoprotein
chr2_+_228029281 0.191 ENST00000396578.3
COL4A3
collagen, type IV, alpha 3 (Goodpasture antigen)
chr16_-_70323422 0.191 ENST00000261772.8
AARS
alanyl-tRNA synthetase
chr12_-_122750957 0.191 ENST00000451053.2
VPS33A
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr16_-_75150665 0.191 ENST00000300051.4
ENST00000450168.2
LDHD

lactate dehydrogenase D

chr16_-_2827128 0.191 ENST00000494946.2
ENST00000409477.1
ENST00000572954.1
ENST00000262306.7
ENST00000409906.4
TCEB2




transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)




chr22_-_38577782 0.189 ENST00000430886.1
ENST00000332509.3
ENST00000447598.2
ENST00000435484.1
ENST00000402064.1
ENST00000436218.1
PLA2G6





phospholipase A2, group VI (cytosolic, calcium-independent)





chr5_+_41904431 0.189 ENST00000381647.2
C5orf51
chromosome 5 open reading frame 51
chr12_-_40499831 0.186 ENST00000380858.1
SLC2A13
solute carrier family 2 (facilitated glucose transporter), member 13
chr22_+_38203898 0.185 ENST00000323205.6
ENST00000248924.6
ENST00000445195.1
GCAT


glycine C-acetyltransferase


chr2_+_191221240 0.184 ENST00000409027.1
ENST00000458193.1
INPP1

inositol polyphosphate-1-phosphatase

chr2_+_85981008 0.183 ENST00000306279.3
ATOH8
atonal homolog 8 (Drosophila)
chr11_+_66360665 0.183 ENST00000310190.4
CCS
copper chaperone for superoxide dismutase
chr2_+_120187465 0.179 ENST00000409826.1
ENST00000417645.1
TMEM37

transmembrane protein 37

chr17_+_79336034 0.179 ENST00000574472.1
RP11-1055B8.2
RP11-1055B8.2
chr16_-_4588391 0.178 ENST00000586728.1
CDIP1
cell death-inducing p53 target 1
chr2_-_176867534 0.178 ENST00000445472.1
KIAA1715
KIAA1715
chr17_+_48450575 0.178 ENST00000338165.4
ENST00000393271.2
ENST00000511519.2
EME1


essential meiotic structure-specific endonuclease 1


chr11_-_57283159 0.176 ENST00000533263.1
ENST00000278426.3
SLC43A1

solute carrier family 43 (amino acid system L transporter), member 1

chr6_-_44225231 0.176 ENST00000538577.1
ENST00000537814.1
ENST00000393810.1
ENST00000393812.3
SLC35B2



solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2



chr19_+_11546153 0.175 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
PRKCSH


protein kinase C substrate 80K-H


chr9_+_133320339 0.175 ENST00000372394.1
ENST00000372393.3
ENST00000422569.1
ASS1


argininosuccinate synthase 1


chr8_-_22089845 0.174 ENST00000454243.2
PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr19_+_11546093 0.171 ENST00000591462.1
PRKCSH
protein kinase C substrate 80K-H
chr7_-_150777874 0.170 ENST00000540185.1
FASTK
Fas-activated serine/threonine kinase
chr14_-_20922960 0.170 ENST00000553640.1
ENST00000488532.2
OSGEP

O-sialoglycoprotein endopeptidase

chr19_+_12848299 0.170 ENST00000357332.3
ASNA1
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
chr17_-_6915616 0.169 ENST00000575889.1
AC027763.2
Uncharacterized protein
chr5_-_1799965 0.168 ENST00000508987.1
MRPL36
mitochondrial ribosomal protein L36
chr11_-_67210930 0.168 ENST00000453768.2
ENST00000545016.1
ENST00000341356.5
CORO1B


coronin, actin binding protein, 1B


chr2_+_176981307 0.167 ENST00000249501.4
HOXD10
homeobox D10
chr12_-_56709786 0.166 ENST00000547423.1
ENST00000548360.1
ENST00000551475.1
RP11-977G19.10

CNPY2
Uncharacterized protein

canopy FGF signaling regulator 2
chr1_+_32712815 0.164 ENST00000373582.3
FAM167B
family with sequence similarity 167, member B
chr17_+_42264556 0.164 ENST00000319511.6
ENST00000589785.1
ENST00000592825.1
ENST00000589184.1
TMUB2



transmembrane and ubiquitin-like domain containing 2



chr6_-_10435032 0.162 ENST00000491317.1
ENST00000496285.1
ENST00000479822.1
ENST00000487130.1
LINC00518



long intergenic non-protein coding RNA 518



chr16_+_4421841 0.162 ENST00000304735.3
VASN
vasorin
chr17_+_42977062 0.161 ENST00000410006.2
ENST00000357776.2
ENST00000410027.1
CCDC103


coiled-coil domain containing 103



Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.5 1.6 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.3 1.0 GO:0043181 vacuolar sequestering(GO:0043181)
0.3 1.3 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.3 0.3 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.3 0.8 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.2 1.9 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.2 0.9 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.2 0.8 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.2 0.5 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.1 0.7 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.1 0.5 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 1.0 GO:0002005 angiotensin catabolic process in blood(GO:0002005)
0.1 1.1 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.1 0.5 GO:1904481 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.1 1.0 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.1 0.5 GO:0072255 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1 0.3 GO:0006566 threonine metabolic process(GO:0006566)
0.1 1.4 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 0.6 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.1 0.7 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.3 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.1 0.4 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.8 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.3 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 0.2 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 1.6 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.1 0.3 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 0.3 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.1 0.8 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.1 0.2 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.1 0.2 GO:0019516 lactate oxidation(GO:0019516)
0.1 0.2 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 0.1 GO:0045342 MHC class II biosynthetic process(GO:0045342) regulation of MHC class II biosynthetic process(GO:0045346) negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1 0.3 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1 0.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.2 GO:1902559 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.1 0.2 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.2 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.1 0.2 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.1 0.2 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.0 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.2 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.7 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.3 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.0 0.9 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.4 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.0 0.1 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.3 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.3 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.0 0.1 GO:2000174 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.0 0.4 GO:1904378 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.2 GO:2001151 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.0 0.2 GO:0046203 spermidine catabolic process(GO:0046203)
0.0 0.1 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 1.6 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.2 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.1 GO:1901895 regulation of interleukin-18 production(GO:0032661) positive regulation of interferon-alpha biosynthetic process(GO:0045356) negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.0 0.3 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) response to hypobaric hypoxia(GO:1990910)
0.0 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.3 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0036483 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
0.0 0.4 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.1 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.1 GO:0072053 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.0 0.2 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.3 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:1901804 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0 0.1 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.0 0.1 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.3 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:1901798 positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:0070295 transformation of host cell by virus(GO:0019087) renal water absorption(GO:0070295)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:0032439 endosome localization(GO:0032439)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.0 0.2 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.1 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.0 GO:0014717 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901) regulation of skeletal muscle tissue regeneration(GO:0043416)
0.0 0.1 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.1 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.0 0.2 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.1 GO:0043096 purine nucleobase salvage(GO:0043096)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.1 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.1 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.1 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.0 0.0 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.2 GO:0009227 UDP-N-acetylglucosamine catabolic process(GO:0006049) nucleotide-sugar catabolic process(GO:0009227)
0.0 1.7 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.3 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.0 0.2 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.8 GO:0097421 liver regeneration(GO:0097421)
0.0 0.1 GO:0001828 inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.1 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.1 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.3 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.8 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.3 GO:2000615 regulation of histone H3-K9 acetylation(GO:2000615)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.0 GO:0050823 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.0 0.0 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.0 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.0 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.0 0.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.1 GO:0097473 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.2 GO:0051597 response to methylmercury(GO:0051597)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.0 GO:0015817 histidine transport(GO:0015817) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.0 GO:0031052 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) oncogene-induced cell senescence(GO:0090402) regulation of cellular response to X-ray(GO:2000683) positive regulation of cellular response to X-ray(GO:2000685) regulation of cellular response to drug(GO:2001038)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.1 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693) semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.0 GO:0007521 muscle cell fate determination(GO:0007521)
0.0 0.1 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.0 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.0 GO:2001033 negative regulation of double-strand break repair via nonhomologous end joining(GO:2001033)
0.0 0.1 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.3 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.0 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.7 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.2 GO:0051450 myoblast proliferation(GO:0051450)
0.0 0.4 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.0 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.0 0.0 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.6 GO:0009268 response to pH(GO:0009268)
0.0 0.1 GO:1901073 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.0 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.0 GO:0019348 dolichol metabolic process(GO:0019348)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.1 1.0 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.8 GO:0044194 cytolytic granule(GO:0044194)
0.1 0.9 GO:0097413 Lewy body(GO:0097413)
0.1 0.8 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.6 GO:0070552 BRISC complex(GO:0070552)
0.1 0.5 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.3 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.4 GO:0097452 GAIT complex(GO:0097452)
0.0 1.4 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.8 GO:0030897 HOPS complex(GO:0030897)
0.0 2.7 GO:0016235 aggresome(GO:0016235)
0.0 0.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.0 0.6 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 0.4 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.4 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.3 GO:0005610 laminin-5 complex(GO:0005610)
0.0 2.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 3.5 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.1 GO:0030120 vesicle coat(GO:0030120) clathrin vesicle coat(GO:0030125)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.3 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 1.8 GO:0005776 autophagosome(GO:0005776)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 1.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.0 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.3 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.0 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.3 0.8 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.3 1.0 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.2 0.7 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.2 0.9 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.2 0.6 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.2 0.9 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.9 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.4 GO:0004458 D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898)
0.1 0.8 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.3 GO:0070538 oleic acid binding(GO:0070538)
0.1 1.1 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 1.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.3 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.1 2.3 GO:0015929 hexosaminidase activity(GO:0015929)
0.1 0.4 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.1 0.5 GO:0016213 linoleoyl-CoA desaturase activity(GO:0016213) 5'-flap endonuclease activity(GO:0017108)
0.1 0.2 GO:0048257 3'-flap endonuclease activity(GO:0048257)
0.1 0.3 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.7 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.2 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.1 1.0 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.1 0.2 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.2 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.3 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 0.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.2 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.1 0.2 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 2.7 GO:0005109 frizzled binding(GO:0005109)
0.1 0.2 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.1 0.7 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 0.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 1.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.3 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.0 0.3 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.1 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.0 1.6 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 1.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.9 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0050421 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitric oxide binding(GO:0070026) nitrite reductase activity(GO:0098809)
0.0 0.2 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 1.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.7 GO:0048185 activin binding(GO:0048185)
0.0 0.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.1 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.4 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.1 GO:0002054 nucleobase binding(GO:0002054) purine nucleobase binding(GO:0002060)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 1.7 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.0 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 1.3 GO:0005507 copper ion binding(GO:0005507)
0.0 0.0 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0001016 RNA polymerase III regulatory region DNA binding(GO:0001016)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.3 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 1.6 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.4 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)
0.0 0.0 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0005537 mannose binding(GO:0005537)
0.0 0.0 GO:0035501 MH1 domain binding(GO:0035501)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.0 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.6 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 1.5 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.6 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.0 1.3 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 2.0 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.3 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 1.1 PID_ATR_PATHWAY ATR signaling pathway
0.0 1.0 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade
0.1 2.6 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.8 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.7 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.5 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.3 REACTOME_PROSTANOID_LIGAND_RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.6 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.6 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.8 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 1.5 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 3.0 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 2.7 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PE Genes involved in Acyl chain remodelling of PE
0.0 0.1 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.3 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.0 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.5 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis