Motif ID: SPIB

Z-value: 0.548


Transcription factors associated with SPIB:

Gene SymbolEntrez IDGene Name
SPIB ENSG00000269404.2 SPIB

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SPIBhg19_v2_chr19_+_50922187_509222150.265.0e-01Click!


Activity profile for motif SPIB.

activity profile for motif SPIB


Sorted Z-values histogram for motif SPIB

Sorted Z-values for motif SPIB



Network of associatons between targets according to the STRING database.



First level regulatory network of SPIB

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_120466650 0.956 ENST00000355622.6
TLR4
toll-like receptor 4
chr9_+_120466610 0.866 ENST00000394487.4
TLR4
toll-like receptor 4
chr17_-_29641104 0.622 ENST00000577894.1
ENST00000330927.4
EVI2B

ecotropic viral integration site 2B

chr17_-_29641084 0.391 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr5_+_169064245 0.303 ENST00000256935.8
DOCK2
dedicator of cytokinesis 2
chr12_-_15114492 0.279 ENST00000541546.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr8_-_101733794 0.274 ENST00000523555.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr17_-_76356148 0.248 ENST00000587578.1
ENST00000330871.2
SOCS3

suppressor of cytokine signaling 3

chr8_-_101734308 0.238 ENST00000519004.1
ENST00000519363.1
ENST00000520142.1
PABPC1


poly(A) binding protein, cytoplasmic 1


chr8_-_101734170 0.233 ENST00000522387.1
ENST00000518196.1
PABPC1

poly(A) binding protein, cytoplasmic 1

chr12_-_120663792 0.233 ENST00000546532.1
ENST00000548912.1
PXN

paxillin

chr12_-_15114191 0.217 ENST00000541380.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr1_+_120839412 0.206 ENST00000355228.4
FAM72B
family with sequence similarity 72, member B
chr10_-_121302195 0.195 ENST00000369103.2
RGS10
regulator of G-protein signaling 10
chr11_-_102401469 0.194 ENST00000260227.4
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr10_-_52008313 0.192 ENST00000329428.6
ENST00000395526.4
ENST00000447815.1
ASAH2


N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2


chr2_+_102972363 0.183 ENST00000409599.1
IL18R1
interleukin 18 receptor 1
chr1_+_206138884 0.180 ENST00000341209.5
ENST00000607379.1
FAM72A

family with sequence similarity 72, member A

chr19_+_16254488 0.179 ENST00000588246.1
ENST00000593031.1
HSH2D

hematopoietic SH2 domain containing

chr12_-_15114603 0.169 ENST00000228945.4
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr9_+_109625378 0.165 ENST00000277225.5
ENST00000457913.1
ENST00000472574.1
ZNF462


zinc finger protein 462


chr11_-_10920838 0.160 ENST00000503469.2
CTD-2003C8.2
CTD-2003C8.2
chr1_-_159893507 0.156 ENST00000368096.1
TAGLN2
transgelin 2
chr8_+_74903580 0.149 ENST00000284818.2
ENST00000518893.1
LY96

lymphocyte antigen 96

chr15_+_91427642 0.148 ENST00000328850.3
ENST00000414248.2
FES

feline sarcoma oncogene

chr6_-_144385698 0.147 ENST00000444202.1
ENST00000437412.1
PLAGL1

pleiomorphic adenoma gene-like 1

chr4_+_110834033 0.147 ENST00000509793.1
ENST00000265171.5
EGF

epidermal growth factor

chr6_-_56708459 0.146 ENST00000370788.2
DST
dystonin
chr8_+_125985531 0.143 ENST00000319286.5
ZNF572
zinc finger protein 572
chr9_+_127023704 0.142 ENST00000373596.1
ENST00000425237.1
NEK6

NIMA-related kinase 6

chrX_+_11129388 0.135 ENST00000321143.4
ENST00000380763.3
ENST00000380762.4
HCCS


holocytochrome c synthase


chr7_-_135662056 0.135 ENST00000393085.3
ENST00000435723.1
MTPN

myotrophin

chr2_+_233925064 0.133 ENST00000359570.5
ENST00000538935.1
INPP5D

inositol polyphosphate-5-phosphatase, 145kDa

chr6_-_56707943 0.132 ENST00000370769.4
ENST00000421834.2
ENST00000312431.6
ENST00000361203.3
ENST00000523817.1
DST




dystonin




chr14_+_96968802 0.131 ENST00000556619.1
ENST00000392990.2
PAPOLA

poly(A) polymerase alpha

chr11_+_67250490 0.131 ENST00000528641.2
ENST00000279146.3
AIP

aryl hydrocarbon receptor interacting protein

chrX_+_24072833 0.125 ENST00000253039.4
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr15_-_65809581 0.122 ENST00000341861.5
DPP8
dipeptidyl-peptidase 8
chr1_+_66796401 0.122 ENST00000528771.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr14_+_96968707 0.122 ENST00000216277.8
ENST00000557320.1
ENST00000557471.1
PAPOLA


poly(A) polymerase alpha


chr1_+_120839005 0.121 ENST00000369390.3
ENST00000452190.1
FAM72B

family with sequence similarity 72, member B

chr14_+_102228123 0.118 ENST00000422945.2
ENST00000554442.1
ENST00000556260.2
ENST00000328724.5
ENST00000557268.1
PPP2R5C




protein phosphatase 2, regulatory subunit B', gamma




chr22_-_37880543 0.116 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr19_+_49838653 0.116 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
CD37





CD37 molecule





chr17_-_1012305 0.114 ENST00000291107.2
ABR
active BCR-related
chr19_-_9420249 0.113 ENST00000591998.1
ZNF699
zinc finger protein 699
chrX_+_24073048 0.113 ENST00000423068.1
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr1_-_43637915 0.113 ENST00000236051.2
EBNA1BP2
EBNA1 binding protein 2
chr5_+_173315283 0.112 ENST00000265085.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr14_+_102276132 0.110 ENST00000350249.3
ENST00000557621.1
ENST00000556946.1
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr15_-_65810042 0.109 ENST00000321147.6
DPP8
dipeptidyl-peptidase 8
chr1_+_206138457 0.107 ENST00000367128.3
ENST00000431655.2
FAM72A

family with sequence similarity 72, member A

chr10_-_79789291 0.106 ENST00000372371.3
POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr19_+_6772710 0.105 ENST00000304076.2
ENST00000602142.1
ENST00000596764.1
VAV1


vav 1 guanine nucleotide exchange factor


chr12_+_122018697 0.104 ENST00000541574.1
RP13-941N14.1
RP13-941N14.1
chr15_-_65809991 0.101 ENST00000559526.1
ENST00000358939.4
ENST00000560665.1
ENST00000321118.7
ENST00000339244.5
ENST00000300141.6
DPP8





dipeptidyl-peptidase 8





chr17_+_28443819 0.100 ENST00000479218.2
NSRP1
nuclear speckle splicing regulatory protein 1
chr5_+_159848854 0.098 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
PTTG1


pituitary tumor-transforming 1


chr1_-_143913143 0.096 ENST00000400889.1
FAM72D
family with sequence similarity 72, member D
chr17_+_76356516 0.096 ENST00000592569.1
RP11-806H10.4
RP11-806H10.4
chr12_-_80083807 0.094 ENST00000551712.1
PAWR
PRKC, apoptosis, WT1, regulator
chr19_-_54804173 0.092 ENST00000391744.3
ENST00000251390.3
LILRA3

leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3

chr1_-_17380630 0.092 ENST00000375499.3
SDHB
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr5_+_102455968 0.091 ENST00000358359.3
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr17_+_75137034 0.091 ENST00000436233.4
ENST00000443798.4
SEC14L1

SEC14-like 1 (S. cerevisiae)

chr7_+_148982396 0.091 ENST00000418158.2
ZNF783
zinc finger family member 783
chr1_+_151171012 0.089 ENST00000349792.5
ENST00000409426.1
ENST00000441902.2
ENST00000368890.4
ENST00000424999.1
ENST00000368888.4
PIP5K1A





phosphatidylinositol-4-phosphate 5-kinase, type I, alpha





chr1_-_175161890 0.089 ENST00000545251.2
ENST00000423313.1
KIAA0040

KIAA0040

chr16_+_70695570 0.087 ENST00000597002.1
FLJ00418
FLJ00418
chr22_-_37640456 0.087 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
RAC2


ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)


chr8_-_25281747 0.087 ENST00000421054.2
GNRH1
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr16_+_31213206 0.087 ENST00000561916.2
C16orf98
chromosome 16 open reading frame 98
chr15_-_65809625 0.087 ENST00000560436.1
DPP8
dipeptidyl-peptidase 8
chr9_+_127624387 0.085 ENST00000353214.2
ARPC5L
actin related protein 2/3 complex, subunit 5-like
chr19_+_2476116 0.084 ENST00000215631.4
ENST00000587345.1
GADD45B

growth arrest and DNA-damage-inducible, beta

chr10_-_977564 0.084 ENST00000406525.2
LARP4B
La ribonucleoprotein domain family, member 4B
chr16_+_69373323 0.083 ENST00000254940.5
NIP7
NIP7, nucleolar pre-rRNA processing protein
chr10_+_104613980 0.083 ENST00000339834.5
C10orf32
chromosome 10 open reading frame 32
chr12_+_49717019 0.082 ENST00000549275.1
ENST00000551245.1
ENST00000380327.5
ENST00000548311.1
ENST00000550346.1
ENST00000550709.1
ENST00000549534.1
ENST00000257909.3
TROAP







trophinin associated protein







chr15_+_91427691 0.081 ENST00000559355.1
ENST00000394302.1
FES

feline sarcoma oncogene

chr2_-_208031943 0.080 ENST00000421199.1
ENST00000457962.1
KLF7

Kruppel-like factor 7 (ubiquitous)

chr14_+_102276209 0.080 ENST00000445439.3
ENST00000334743.5
ENST00000557095.1
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr17_-_73389737 0.080 ENST00000392563.1
GRB2
growth factor receptor-bound protein 2
chr16_+_57392684 0.079 ENST00000219235.4
CCL22
chemokine (C-C motif) ligand 22
chr15_+_83209620 0.078 ENST00000568285.1
RP11-379H8.1
Uncharacterized protein
chr14_-_67826538 0.078 ENST00000553687.1
ATP6V1D
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chr8_+_98656693 0.078 ENST00000519934.1
MTDH
metadherin
chr6_-_139308777 0.078 ENST00000529597.1
ENST00000415951.2
ENST00000367663.4
ENST00000409812.2
REPS1



RALBP1 associated Eps domain containing 1



chr17_+_75136980 0.077 ENST00000585618.1
ENST00000413679.2
SEC14L1

SEC14-like 1 (S. cerevisiae)

chr19_-_54746600 0.077 ENST00000407860.2
ENST00000245621.5
ENST00000270464.5
ENST00000419410.2
ENST00000391735.3
ENST00000396365.2
ENST00000440558.2
LILRB3
LILRA6





leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6





chr17_+_7835419 0.077 ENST00000576538.1
ENST00000380262.3
ENST00000563694.1
ENST00000380255.3
ENST00000570782.1
CNTROB




centrobin, centrosomal BRCA2 interacting protein




chr5_+_64859066 0.076 ENST00000261308.5
ENST00000535264.1
ENST00000538977.1
PPWD1


peptidylprolyl isomerase domain and WD repeat containing 1


chr1_-_38325256 0.075 ENST00000373036.4
MTF1
metal-regulatory transcription factor 1
chr3_-_179169330 0.075 ENST00000232564.3
GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr1_-_43282945 0.075 ENST00000537227.1
CCDC23
coiled-coil domain containing 23
chr2_+_68592305 0.075 ENST00000234313.7
PLEK
pleckstrin
chr1_-_43638168 0.075 ENST00000431635.2
EBNA1BP2
EBNA1 binding protein 2
chr19_+_54371114 0.074 ENST00000448420.1
ENST00000439000.1
ENST00000391770.4
ENST00000391771.1
MYADM



myeloid-associated differentiation marker



chr2_-_161350305 0.073 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr10_-_103578162 0.072 ENST00000361464.3
ENST00000357797.5
ENST00000370094.3
MGEA5


meningioma expressed antigen 5 (hyaluronidase)


chr8_+_39770803 0.072 ENST00000518237.1
IDO1
indoleamine 2,3-dioxygenase 1
chrX_-_139015153 0.072 ENST00000370557.1
ATP11C
ATPase, class VI, type 11C
chr1_+_167599532 0.072 ENST00000537350.1
RCSD1
RCSD domain containing 1
chr12_+_8276433 0.072 ENST00000345999.3
ENST00000352620.3
ENST00000360500.3
CLEC4A


C-type lectin domain family 4, member A


chr3_-_11685345 0.071 ENST00000430365.2
VGLL4
vestigial like 4 (Drosophila)
chr16_+_57576584 0.071 ENST00000340339.4
GPR114
G protein-coupled receptor 114
chr1_-_43282906 0.071 ENST00000372521.4
CCDC23
coiled-coil domain containing 23
chr7_+_86781916 0.069 ENST00000579592.1
ENST00000434534.1
DMTF1

cyclin D binding myb-like transcription factor 1

chr3_-_160283348 0.069 ENST00000334256.4
KPNA4
karyopherin alpha 4 (importin alpha 3)
chr5_+_102455853 0.068 ENST00000515845.1
ENST00000321521.9
ENST00000507921.1
PPIP5K2


diphosphoinositol pentakisphosphate kinase 2


chr15_-_33360085 0.068 ENST00000334528.9
FMN1
formin 1
chr10_-_99161033 0.068 ENST00000315563.6
ENST00000370992.4
ENST00000414986.1
RRP12


ribosomal RNA processing 12 homolog (S. cerevisiae)


chr12_+_49717081 0.068 ENST00000547807.1
ENST00000551567.1
TROAP

trophinin associated protein

chr2_+_233925038 0.068 ENST00000451407.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr14_+_67291158 0.068 ENST00000555456.1
GPHN
gephyrin
chr20_-_20033052 0.067 ENST00000536226.1
CRNKL1
crooked neck pre-mRNA splicing factor 1
chr1_+_179851999 0.067 ENST00000527391.1
TOR1AIP1
torsin A interacting protein 1
chr1_+_78383813 0.067 ENST00000342754.5
NEXN
nexilin (F actin binding protein)
chr12_-_15114658 0.067 ENST00000542276.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr10_-_103578182 0.066 ENST00000439817.1
MGEA5
meningioma expressed antigen 5 (hyaluronidase)
chr1_+_40505891 0.066 ENST00000372797.3
ENST00000372802.1
ENST00000449311.1
CAP1


CAP, adenylate cyclase-associated protein 1 (yeast)


chr3_+_28390637 0.066 ENST00000420223.1
ENST00000383768.2
ZCWPW2

zinc finger, CW type with PWWP domain 2

chr2_-_8723918 0.066 ENST00000454224.1
AC011747.4
AC011747.4
chr8_+_104426942 0.065 ENST00000297579.5
DCAF13
DDB1 and CUL4 associated factor 13
chr1_+_167298281 0.064 ENST00000367862.5
POU2F1
POU class 2 homeobox 1
chr17_-_73389854 0.064 ENST00000578961.1
ENST00000392564.1
ENST00000582582.1
GRB2


growth factor receptor-bound protein 2


chr1_+_179851893 0.064 ENST00000531630.2
TOR1AIP1
torsin A interacting protein 1
chr8_-_101962777 0.064 ENST00000395951.3
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr19_-_16770915 0.064 ENST00000358726.6
ENST00000597711.1
ENST00000487416.2
ENST00000593459.1
SMIM7


CTC-429P9.4
small integral membrane protein 7


Small integral membrane protein 7; Uncharacterized protein
chr7_+_74188309 0.064 ENST00000289473.4
ENST00000433458.1
NCF1

neutrophil cytosolic factor 1

chr17_-_56429500 0.063 ENST00000225504.3
SUPT4H1
suppressor of Ty 4 homolog 1 (S. cerevisiae)
chr1_+_43855545 0.062 ENST00000372450.4
ENST00000310739.4
SZT2

seizure threshold 2 homolog (mouse)

chr2_-_74405929 0.062 ENST00000396049.4
MOB1A
MOB kinase activator 1A
chr6_+_116782527 0.061 ENST00000368606.3
ENST00000368605.1
FAM26F

family with sequence similarity 26, member F

chr3_-_28390298 0.061 ENST00000457172.1
AZI2
5-azacytidine induced 2
chr1_+_179851410 0.061 ENST00000271583.3
ENST00000606911.2
TOR1AIP1

torsin A interacting protein 1

chr9_+_36190905 0.060 ENST00000345519.5
ENST00000470744.1
ENST00000242285.6
ENST00000466396.1
ENST00000396603.2
CLTA




clathrin, light chain A




chr1_+_26644441 0.060 ENST00000374213.2
CD52
CD52 molecule
chr12_+_8276224 0.059 ENST00000229332.5
CLEC4A
C-type lectin domain family 4, member A
chr5_-_10249990 0.058 ENST00000511437.1
ENST00000280330.8
ENST00000510047.1
FAM173B


family with sequence similarity 173, member B


chr12_+_124086632 0.058 ENST00000238146.4
ENST00000538744.1
DDX55

DEAD (Asp-Glu-Ala-Asp) box polypeptide 55

chr2_+_233924548 0.057 ENST00000422935.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr9_+_36190853 0.057 ENST00000433436.2
ENST00000538225.1
ENST00000540080.1
CLTA


clathrin, light chain A


chr4_-_47916543 0.057 ENST00000507489.1
NFXL1
nuclear transcription factor, X-box binding-like 1
chr2_+_173940163 0.056 ENST00000539448.1
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr4_+_76871883 0.056 ENST00000599764.1
AC110615.1
Uncharacterized protein
chr3_+_23847432 0.056 ENST00000346855.3
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr1_+_179851823 0.056 ENST00000435319.4
TOR1AIP1
torsin A interacting protein 1
chr6_+_126102292 0.055 ENST00000368357.3
NCOA7
nuclear receptor coactivator 7
chrX_+_11777671 0.054 ENST00000380693.3
ENST00000380692.2
MSL3

male-specific lethal 3 homolog (Drosophila)

chr3_-_180397256 0.054 ENST00000442201.2
CCDC39
coiled-coil domain containing 39
chr10_-_33623310 0.054 ENST00000395995.1
ENST00000374823.5
ENST00000374821.5
ENST00000374816.3
NRP1



neuropilin 1



chr3_-_28390120 0.054 ENST00000334100.6
AZI2
5-azacytidine induced 2
chr3_-_195603566 0.053 ENST00000424563.1
ENST00000411741.1
TNK2

tyrosine kinase, non-receptor, 2

chr2_+_109237717 0.053 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr4_-_102268708 0.053 ENST00000525819.1
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr15_+_50716576 0.053 ENST00000560297.1
ENST00000307179.4
ENST00000396444.3
ENST00000433963.1
ENST00000425032.3
USP8




ubiquitin specific peptidase 8




chr22_-_37640277 0.053 ENST00000401529.3
ENST00000249071.6
RAC2

ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)

chr2_-_190044480 0.052 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr5_-_158757895 0.052 ENST00000231228.2
IL12B
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
chr4_+_159727272 0.051 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr19_+_35940486 0.051 ENST00000246549.2
FFAR2
free fatty acid receptor 2
chr8_+_121457642 0.050 ENST00000305949.1
MTBP
Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa
chr22_-_40859415 0.050 ENST00000402630.1
ENST00000407029.1
MKL1

megakaryoblastic leukemia (translocation) 1

chr9_-_2844058 0.050 ENST00000397885.2
KIAA0020
KIAA0020
chr20_-_5931051 0.050 ENST00000453074.2
TRMT6
tRNA methyltransferase 6 homolog (S. cerevisiae)
chr3_+_23847394 0.049 ENST00000306627.3
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr7_-_112635675 0.049 ENST00000447785.1
ENST00000451962.1
AC018464.3

AC018464.3

chr10_+_72238517 0.048 ENST00000263563.6
PALD1
phosphatase domain containing, paladin 1
chr20_-_5931109 0.048 ENST00000203001.2
TRMT6
tRNA methyltransferase 6 homolog (S. cerevisiae)
chr2_+_173940442 0.048 ENST00000409176.2
ENST00000338983.3
ENST00000431503.2
MLTK


Mitogen-activated protein kinase kinase kinase MLT


chr6_-_47010061 0.048 ENST00000371253.2
GPR110
G protein-coupled receptor 110
chrX_+_48398053 0.048 ENST00000537536.1
ENST00000418627.1
TBC1D25

TBC1 domain family, member 25

chr10_+_114133773 0.048 ENST00000354655.4
ACSL5
acyl-CoA synthetase long-chain family member 5
chr21_-_36421626 0.048 ENST00000300305.3
RUNX1
runt-related transcription factor 1
chr7_+_86781847 0.047 ENST00000432366.2
ENST00000423590.2
ENST00000394703.5
DMTF1


cyclin D binding myb-like transcription factor 1


chr3_-_20227720 0.047 ENST00000412997.1
SGOL1
shugoshin-like 1 (S. pombe)
chr1_+_39456895 0.047 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
AKIRIN1


akirin 1


chr9_+_104296163 0.047 ENST00000374819.2
ENST00000479306.1
RNF20

ring finger protein 20, E3 ubiquitin protein ligase

chr1_-_220445757 0.047 ENST00000358951.2
RAB3GAP2
RAB3 GTPase activating protein subunit 2 (non-catalytic)
chr13_+_53602894 0.047 ENST00000219022.2
OLFM4
olfactomedin 4
chr3_-_28390415 0.047 ENST00000414162.1
ENST00000420543.2
AZI2

5-azacytidine induced 2

chr5_-_87980587 0.047 ENST00000509783.1
ENST00000509405.1
ENST00000506978.1
ENST00000509265.1
ENST00000513805.1
LINC00461




long intergenic non-protein coding RNA 461




chr22_+_39410287 0.046 ENST00000381568.4
APOBEC3D
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
chr9_+_104296122 0.046 ENST00000389120.3
RNF20
ring finger protein 20, E3 ubiquitin protein ligase
chr12_-_9102224 0.046 ENST00000543845.1
ENST00000544245.1
M6PR

mannose-6-phosphate receptor (cation dependent)

chr15_-_66084621 0.045 ENST00000564674.1
DENND4A
DENN/MADD domain containing 4A
chr14_-_50319482 0.045 ENST00000546046.1
ENST00000555970.1
ENST00000554626.1
ENST00000545773.1
ENST00000556672.1
NEMF




nuclear export mediator factor




chr16_-_30537839 0.045 ENST00000380412.5
ZNF768
zinc finger protein 768
chr1_-_156675368 0.045 ENST00000368222.3
CRABP2
cellular retinoic acid binding protein 2
chrX_-_40594755 0.045 ENST00000324817.1
MED14
mediator complex subunit 14
chr18_+_18943554 0.045 ENST00000580732.2
GREB1L
growth regulation by estrogen in breast cancer-like
chr19_-_54850417 0.045 ENST00000291759.4
LILRA4
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
chr4_-_102268484 0.044 ENST00000394853.4
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr17_+_28443799 0.044 ENST00000584423.1
ENST00000247026.5
NSRP1

nuclear speckle splicing regulatory protein 1

chr9_-_95640218 0.044 ENST00000395506.3
ENST00000375495.3
ENST00000332591.6
ZNF484


zinc finger protein 484


chr12_+_25205446 0.044 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP


lymphoid-restricted membrane protein


chr2_-_153573887 0.043 ENST00000493468.2
ENST00000545856.1
PRPF40A

PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)

chr3_-_20227619 0.043 ENST00000425061.1
ENST00000443724.1
ENST00000421451.1
ENST00000452020.1
ENST00000417364.1
ENST00000306698.2
ENST00000419233.2
ENST00000263753.4
ENST00000383774.1
ENST00000437051.1
ENST00000412868.1
ENST00000429446.3
ENST00000442720.1
SGOL1












shugoshin-like 1 (S. pombe)












chr19_-_17375541 0.043 ENST00000252597.3
USHBP1
Usher syndrome 1C binding protein 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.1 0.7 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.7 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.3 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.1 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) positive regulation of connective tissue replacement(GO:1905205)
0.0 0.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.3 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.1 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.1 GO:0002877 leukocyte chemotaxis involved in inflammatory response(GO:0002232) acute inflammatory response to non-antigenic stimulus(GO:0002525) regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
0.0 0.0 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.0 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 0.1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.2 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.0 0.0 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.1 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.2 GO:0071351 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.0 0.0 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.0 0.1 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.1 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.1 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.1 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) positive regulation of retinal ganglion cell axon guidance(GO:1902336) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 0.1 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.2 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.3 GO:0031673 H zone(GO:0031673)
0.0 0.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.0 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0032044 DSIF complex(GO:0032044)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.7 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.7 GO:0008494 translation activator activity(GO:0008494)
0.0 0.3 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0051538 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.2 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.1 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.3 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.0 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.3 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.0 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.7 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.2 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling