Motif ID: SOX7

Z-value: 0.390


Transcription factors associated with SOX7:

Gene SymbolEntrez IDGene Name
SOX7 ENSG00000171056.6 SOX7
SOX7 ENSG00000258724.1 SOX7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SOX7hg19_v2_chr8_-_10697281_106973650.618.0e-02Click!


Activity profile for motif SOX7.

activity profile for motif SOX7


Sorted Z-values histogram for motif SOX7

Sorted Z-values for motif SOX7



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX7

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_75174180 0.734 ENST00000413830.1
 EPGN
epithelial mitogen
chr10_-_61495760 0.342 ENST00000395347.1
 SLC16A9
solute carrier family 16, member 9
chr4_-_39034542 0.284 ENST00000344606.6
 TMEM156
transmembrane protein 156
chr1_-_89738458 0.281 ENST00000443807.1
 GBP5
guanylate binding protein 5
chr15_+_63414760 0.245 ENST00000557972.1
 LACTB
lactamase, beta
chr19_-_22379753 0.229 ENST00000397121.2
 ZNF676
zinc finger protein 676
chr12_-_90049828 0.203 ENST00000261173.2
ENST00000348959.3
 ATP2B1

ATPase, Ca++ transporting, plasma membrane 1

chr12_-_90049878 0.190 ENST00000359142.3
 ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr7_-_33148975 0.177 ENST00000297157.3
 RP9
retinitis pigmentosa 9 (autosomal dominant)
chr14_-_102771462 0.170 ENST00000522874.1
 MOK
MOK protein kinase
chr8_-_19459993 0.165 ENST00000454498.2
ENST00000520003.1
 CSGALNACT1

chondroitin sulfate N-acetylgalactosaminyltransferase 1

chr1_+_199996733 0.149 ENST00000236914.3
 NR5A2
nuclear receptor subfamily 5, group A, member 2
chr1_-_186430222 0.140 ENST00000391997.2
 PDC
phosducin
chr1_+_223101757 0.136 ENST00000284476.6
 DISP1
dispatched homolog 1 (Drosophila)
chr16_+_22518495 0.134 ENST00000541154.1
 NPIPB5
nuclear pore complex interacting protein family, member B5
chr19_-_21950332 0.131 ENST00000598026.1
 ZNF100
zinc finger protein 100
chr2_-_88285309 0.120 ENST00000420840.2
 RGPD2
RANBP2-like and GRIP domain containing 2
chr12_+_1099675 0.118 ENST00000545318.2
 ERC1
ELKS/RAB6-interacting/CAST family member 1
chr1_+_40810516 0.112 ENST00000435168.2
 SMAP2
small ArfGAP2
chr11_+_3011093 0.099 ENST00000332881.2
 AC131971.1
HCG1782999; PRO0943; Uncharacterized protein
chr16_-_21442874 0.098 ENST00000534903.1
 NPIPB3
nuclear pore complex interacting protein family, member B3
chr1_+_100598691 0.092 ENST00000370143.1
ENST00000370141.2
 TRMT13

tRNA methyltransferase 13 homolog (S. cerevisiae)

chr1_+_10509971 0.090 ENST00000320498.4
 CORT
cortistatin
chr12_+_64173583 0.090 ENST00000261234.6
 TMEM5
transmembrane protein 5
chr4_-_4544061 0.088 ENST00000507908.1
 STX18
syntaxin 18
chr2_+_87144738 0.080 ENST00000559485.1
 RGPD1
RANBP2-like and GRIP domain containing 1
chr6_+_144164455 0.078 ENST00000367576.5
 LTV1
LTV1 homolog (S. cerevisiae)
chr12_-_56693758 0.074 ENST00000547298.1
ENST00000551936.1
ENST00000551253.1
ENST00000551473.1
 CS



citrate synthase



chr14_+_60712463 0.074 ENST00000325642.3
ENST00000529574.1
 PPM1A

protein phosphatase, Mg2+/Mn2+ dependent, 1A

chr2_+_179317994 0.067 ENST00000375129.4
 DFNB59
deafness, autosomal recessive 59
chr1_-_54303934 0.063 ENST00000537333.1
 NDC1
NDC1 transmembrane nucleoporin
chr19_-_2783363 0.061 ENST00000221566.2
 SGTA
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr16_-_279405 0.051 ENST00000430864.1
ENST00000293872.8
ENST00000337351.4
ENST00000397783.1
 LUC7L



LUC7-like (S. cerevisiae)



chr19_-_2783255 0.050 ENST00000589251.1
 SGTA
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr1_+_100598742 0.050 ENST00000370139.1
 TRMT13
tRNA methyltransferase 13 homolog (S. cerevisiae)
chr19_-_5784610 0.047 ENST00000390672.2
ENST00000419421.2
 PRR22

proline rich 22

chr9_-_70465758 0.047 ENST00000489273.1
 CBWD5
COBW domain containing 5
chr16_+_33020496 0.042 ENST00000565407.2
 IGHV3OR16-8
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr7_-_143966381 0.041 ENST00000487179.1
 CTAGE8
CTAGE family, member 8
chr10_-_12084770 0.041 ENST00000357604.5
 UPF2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr13_-_37633567 0.040 ENST00000464744.1
 SUPT20H
suppressor of Ty 20 homolog (S. cerevisiae)
chr17_-_56082455 0.040 ENST00000578794.1
 RP11-159D12.5
Uncharacterized protein
chr19_+_37837185 0.038 ENST00000541583.2
 HKR1
HKR1, GLI-Kruppel zinc finger family member
chr6_+_147527103 0.038 ENST00000179882.6
 STXBP5
syntaxin binding protein 5 (tomosyn)
chr6_+_42531798 0.038 ENST00000372903.2
ENST00000372899.1
ENST00000372901.1
 UBR2


ubiquitin protein ligase E3 component n-recognin 2


chr1_+_156698743 0.038 ENST00000524343.1
 RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr10_+_24738355 0.037 ENST00000307544.6
 KIAA1217
KIAA1217
chr4_-_47983519 0.034 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
 CNGA1


cyclic nucleotide gated channel alpha 1


chr16_-_33647696 0.031 ENST00000558425.1
ENST00000569103.2
 RP11-812E19.9

Uncharacterized protein

chr19_+_37837218 0.031 ENST00000591134.1
 HKR1
HKR1, GLI-Kruppel zinc finger family member
chr3_-_123411191 0.031 ENST00000354792.5
ENST00000508240.1
 MYLK

myosin light chain kinase

chr1_-_43751230 0.027 ENST00000523677.1
 C1orf210
chromosome 1 open reading frame 210
chr10_-_96829246 0.025 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
 CYP2C8


cytochrome P450, family 2, subfamily C, polypeptide 8


chr17_-_39623681 0.024 ENST00000225899.3
 KRT32
keratin 32
chr16_-_28303360 0.023 ENST00000501520.1
 RP11-57A19.2
RP11-57A19.2
chr5_+_161494770 0.022 ENST00000414552.2
ENST00000361925.4
 GABRG2

gamma-aminobutyric acid (GABA) A receptor, gamma 2

chr15_+_66585950 0.020 ENST00000525109.1
 DIS3L
DIS3 mitotic control homolog (S. cerevisiae)-like
chr10_+_96162242 0.014 ENST00000225235.4
 TBC1D12
TBC1 domain family, member 12
chr3_+_107318157 0.014 ENST00000406780.1
 BBX
bobby sox homolog (Drosophila)
chr8_-_82359662 0.007 ENST00000519260.1
ENST00000256103.2
 PMP2

peripheral myelin protein 2

chr4_-_177190364 0.007 ENST00000296525.3
 ASB5
ankyrin repeat and SOCS box containing 5
chr11_+_5775923 0.006 ENST00000317254.3
 OR52N4
olfactory receptor, family 52, subfamily N, member 4 (gene/pseudogene)
chr12_-_123728548 0.005 ENST00000545406.1
 MPHOSPH9
M-phase phosphoprotein 9
chr10_-_17243579 0.005 ENST00000525762.1
ENST00000412821.3
ENST00000351358.4
ENST00000377766.5
ENST00000358282.7
ENST00000488990.1
ENST00000377799.3
 TRDMT1






tRNA aspartic acid methyltransferase 1






chr15_+_75639372 0.004 ENST00000566313.1
ENST00000568059.1
ENST00000568881.1
 NEIL1


nei endonuclease VIII-like 1 (E. coli)


chr17_-_66951382 0.004 ENST00000586539.1
 ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr2_-_68547019 0.003 ENST00000409862.1
 CNRIP1
cannabinoid receptor interacting protein 1
chr8_+_12803176 0.001 ENST00000524591.2
 KIAA1456
KIAA1456

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0072616 interleukin-18 secretion(GO:0072616)
0.0 0.4 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.0 0.7 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.3 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.1 GO:0071790 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.0 0.2 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.1 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0034448 EGO complex(GO:0034448)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0036440 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.0 0.2 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)