Motif ID: SOX30

Z-value: 0.260


Transcription factors associated with SOX30:

Gene SymbolEntrez IDGene Name
SOX30 ENSG00000039600.6 SOX30

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SOX30hg19_v2_chr5_-_157079428_1570794520.541.3e-01Click!


Activity profile for motif SOX30.

activity profile for motif SOX30


Sorted Z-values histogram for motif SOX30

Sorted Z-values for motif SOX30



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX30

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_100770328 0.194 ENST00000223095.4
ENST00000445463.2
 SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr17_-_73149921 0.143 ENST00000481647.1
ENST00000470924.1
 HN1

hematological and neurological expressed 1

chr12_-_49581152 0.141 ENST00000550811.1
 TUBA1A
tubulin, alpha 1a
chr2_-_37899323 0.135 ENST00000295324.3
ENST00000457889.1
 CDC42EP3

CDC42 effector protein (Rho GTPase binding) 3

chr9_-_74383302 0.128 ENST00000377066.5
 TMEM2
transmembrane protein 2
chr2_-_166060552 0.109 ENST00000283254.7
ENST00000453007.1
 SCN3A

sodium channel, voltage-gated, type III, alpha subunit

chr6_+_126240442 0.106 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
 NCOA7


nuclear receptor coactivator 7


chr6_+_12290586 0.097 ENST00000379375.5
 EDN1
endothelin 1
chr2_-_166060382 0.084 ENST00000409101.3
 SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr2_-_166060571 0.082 ENST00000360093.3
 SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr4_+_54243798 0.068 ENST00000337488.6
ENST00000358575.5
ENST00000507922.1
 FIP1L1


factor interacting with PAPOLA and CPSF1


chr14_+_52456193 0.066 ENST00000261700.3
 C14orf166
chromosome 14 open reading frame 166
chr2_+_232573208 0.065 ENST00000409115.3
 PTMA
prothymosin, alpha
chr2_+_232573222 0.060 ENST00000341369.7
ENST00000409683.1
 PTMA

prothymosin, alpha

chr22_+_31488433 0.060 ENST00000455608.1
 SMTN
smoothelin
chr14_+_52456327 0.059 ENST00000556760.1
 C14orf166
chromosome 14 open reading frame 166
chr22_+_46449674 0.059 ENST00000381051.2
 FLJ27365
hsa-mir-4763
chr10_+_70480963 0.055 ENST00000265872.6
ENST00000535016.1
ENST00000538031.1
ENST00000543719.1
ENST00000539539.1
ENST00000543225.1
ENST00000536012.1
ENST00000494903.2
 CCAR1







cell division cycle and apoptosis regulator 1







chr5_-_146461027 0.053 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
 PPP2R2B


protein phosphatase 2, regulatory subunit B, beta


chr11_-_85430088 0.052 ENST00000533057.1
ENST00000533892.1
 SYTL2

synaptotagmin-like 2

chr11_-_85430204 0.051 ENST00000389958.3
ENST00000527794.1
 SYTL2

synaptotagmin-like 2

chr16_+_4545853 0.050 ENST00000575129.1
ENST00000398595.3
ENST00000414777.1
 HMOX2


heme oxygenase (decycling) 2


chr1_+_154401791 0.048 ENST00000476006.1
 IL6R
interleukin 6 receptor
chr20_-_5426380 0.048 ENST00000609252.1
ENST00000422352.1
 LINC00658

long intergenic non-protein coding RNA 658

chr4_+_54243862 0.046 ENST00000306932.6
 FIP1L1
factor interacting with PAPOLA and CPSF1
chrX_+_70503037 0.046 ENST00000535149.1
 NONO
non-POU domain containing, octamer-binding
chr14_+_36295504 0.043 ENST00000216807.7
 BRMS1L
breast cancer metastasis-suppressor 1-like
chr10_+_35415851 0.043 ENST00000374726.3
 CREM
cAMP responsive element modulator
chr15_+_93426514 0.042 ENST00000556722.1
 CHD2
chromodomain helicase DNA binding protein 2
chr1_-_201476274 0.041 ENST00000340006.2
 CSRP1
cysteine and glycine-rich protein 1
chr5_-_134735568 0.041 ENST00000510038.1
ENST00000304332.4
 H2AFY

H2A histone family, member Y

chr1_-_243418621 0.039 ENST00000366544.1
ENST00000366543.1
 CEP170

centrosomal protein 170kDa

chr11_-_85430163 0.038 ENST00000529581.1
ENST00000533577.1
 SYTL2

synaptotagmin-like 2

chr1_+_149239529 0.037 ENST00000457216.2
 RP11-403I13.4
RP11-403I13.4
chr1_-_243418344 0.037 ENST00000366542.1
 CEP170
centrosomal protein 170kDa
chr5_+_60933634 0.036 ENST00000505642.1
 C5orf64
chromosome 5 open reading frame 64
chr4_+_54243917 0.036 ENST00000507166.1
 FIP1L1
factor interacting with PAPOLA and CPSF1
chr1_+_240255166 0.036 ENST00000319653.9
 FMN2
formin 2
chr12_-_11036844 0.035 ENST00000428168.2
 PRH1
proline-rich protein HaeIII subfamily 1
chr11_+_46402744 0.035 ENST00000533952.1
 MDK
midkine (neurite growth-promoting factor 2)
chr5_-_134734901 0.035 ENST00000312469.4
ENST00000423969.2
 H2AFY

H2A histone family, member Y

chrX_+_70503433 0.034 ENST00000276079.8
ENST00000373856.3
ENST00000373841.1
ENST00000420903.1
 NONO



non-POU domain containing, octamer-binding



chrX_+_114874727 0.034 ENST00000543070.1
 PLS3
plastin 3
chr14_+_100070869 0.033 ENST00000502101.2
 RP11-543C4.1
RP11-543C4.1
chrX_+_41192595 0.033 ENST00000399959.2
 DDX3X
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr12_+_95611516 0.033 ENST00000436874.1
 VEZT
vezatin, adherens junctions transmembrane protein
chr12_+_95611569 0.032 ENST00000261219.6
ENST00000551472.1
ENST00000552821.1
 VEZT


vezatin, adherens junctions transmembrane protein


chr5_+_139175380 0.030 ENST00000274710.3
 PSD2
pleckstrin and Sec7 domain containing 2
chr11_+_125365110 0.029 ENST00000527818.1
 AP000708.1
AP000708.1
chr12_+_95611536 0.029 ENST00000549002.1
 VEZT
vezatin, adherens junctions transmembrane protein
chr2_+_99953816 0.028 ENST00000289371.6
 EIF5B
eukaryotic translation initiation factor 5B
chr2_+_207804278 0.028 ENST00000272852.3
 CPO
carboxypeptidase O
chr19_-_44439387 0.028 ENST00000269973.5
 ZNF45
zinc finger protein 45
chr1_-_167883327 0.028 ENST00000476818.2
ENST00000367851.4
ENST00000367848.1
 ADCY10


adenylate cyclase 10 (soluble)


chr11_-_85430356 0.025 ENST00000526999.1
 SYTL2
synaptotagmin-like 2
chr8_-_82024290 0.025 ENST00000220597.4
 PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr4_+_77356248 0.024 ENST00000296043.6
 SHROOM3
shroom family member 3
chr6_-_11779014 0.023 ENST00000229583.5
 ADTRP
androgen-dependent TFPI-regulating protein
chr1_-_243418650 0.023 ENST00000522995.1
 CEP170
centrosomal protein 170kDa
chr4_-_87028478 0.023 ENST00000515400.1
ENST00000395157.3
 MAPK10

mitogen-activated protein kinase 10

chr22_-_30970560 0.023 ENST00000402369.1
ENST00000406361.1
 GAL3ST1

galactose-3-O-sulfotransferase 1

chr12_+_9066472 0.022 ENST00000538657.1
 PHC1
polyhomeotic homolog 1 (Drosophila)
chr4_-_69111401 0.021 ENST00000332644.5
 TMPRSS11B
transmembrane protease, serine 11B
chr2_-_158182322 0.021 ENST00000420719.2
ENST00000409216.1
 ERMN

ermin, ERM-like protein

chr10_-_62060232 0.021 ENST00000503925.1
 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr7_-_121944491 0.020 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
 FEZF1


FEZ family zinc finger 1


chr3_+_19988566 0.019 ENST00000273047.4
 RAB5A
RAB5A, member RAS oncogene family
chr6_+_131958436 0.019 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
 ENPP3



ectonucleotide pyrophosphatase/phosphodiesterase 3



chr2_-_162931052 0.019 ENST00000360534.3
 DPP4
dipeptidyl-peptidase 4
chr1_+_117236734 0.019 ENST00000369482.1
 C1orf137
chromosome 1 open reading frame 137
chr4_-_40516560 0.019 ENST00000513473.1
 RBM47
RNA binding motif protein 47
chr9_-_85882145 0.018 ENST00000328788.1
 FRMD3
FERM domain containing 3
chr1_-_156828810 0.018 ENST00000368195.3
 INSRR
insulin receptor-related receptor
chr2_-_169769787 0.018 ENST00000451987.1
 SPC25
SPC25, NDC80 kinetochore complex component
chr9_+_103235365 0.018 ENST00000374879.4
 TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr1_-_201476220 0.018 ENST00000526723.1
ENST00000524951.1
 CSRP1

cysteine and glycine-rich protein 1

chr3_+_181429704 0.017 ENST00000431565.2
ENST00000325404.1
 SOX2

SRY (sex determining region Y)-box 2

chr3_-_57583130 0.017 ENST00000303436.6
 ARF4
ADP-ribosylation factor 4
chr1_-_85930246 0.017 ENST00000426972.3
 DDAH1
dimethylarginine dimethylaminohydrolase 1
chr3_-_19988462 0.017 ENST00000344838.4
 EFHB
EF-hand domain family, member B
chr6_-_139613269 0.016 ENST00000358430.3
 TXLNB
taxilin beta
chrX_-_24690771 0.016 ENST00000379145.1
 PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr2_+_27719697 0.015 ENST00000264717.2
ENST00000424318.2
 GCKR

glucokinase (hexokinase 4) regulator

chr1_-_167883353 0.015 ENST00000545172.1
 ADCY10
adenylate cyclase 10 (soluble)
chr22_-_30970498 0.015 ENST00000431313.1
 GAL3ST1
galactose-3-O-sulfotransferase 1
chr6_-_11779174 0.014 ENST00000379413.2
 ADTRP
androgen-dependent TFPI-regulating protein
chr15_+_69857515 0.014 ENST00000559477.1
 RP11-279F6.1
RP11-279F6.1
chr1_-_21503337 0.014 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
 EIF4G3



eukaryotic translation initiation factor 4 gamma, 3



chr8_+_24151553 0.013 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
 ADAM28


ADAM metallopeptidase domain 28


chr4_-_176733897 0.013 ENST00000393658.2
 GPM6A
glycoprotein M6A
chr11_-_102576537 0.013 ENST00000260229.4
 MMP27
matrix metallopeptidase 27
chrX_-_117107542 0.012 ENST00000371878.1
 KLHL13
kelch-like family member 13
chr1_+_185014496 0.012 ENST00000367510.3
 RNF2
ring finger protein 2
chr12_-_10251539 0.011 ENST00000420265.2
 CLEC1A
C-type lectin domain family 1, member A
chr11_+_63137251 0.011 ENST00000310969.4
ENST00000279178.3
 SLC22A9

solute carrier family 22 (organic anion transporter), member 9

chr8_+_42195972 0.011 ENST00000532157.1
ENST00000265421.4
ENST00000520008.1
 POLB


polymerase (DNA directed), beta


chr11_+_128563652 0.011 ENST00000527786.2
 FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr7_-_82792215 0.010 ENST00000333891.9
ENST00000423517.2
 PCLO

piccolo presynaptic cytomatrix protein

chr13_+_98795664 0.010 ENST00000376581.5
 FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr1_+_244998918 0.010 ENST00000366528.3
 COX20
COX20 cytochrome C oxidase assembly factor
chr12_+_50898881 0.009 ENST00000301180.5
 DIP2B
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr19_-_17375541 0.009 ENST00000252597.3
 USHBP1
Usher syndrome 1C binding protein 1
chr8_-_141810634 0.009 ENST00000521986.1
ENST00000523539.1
ENST00000538769.1
 PTK2


protein tyrosine kinase 2


chr11_-_102323740 0.009 ENST00000398136.2
 TMEM123
transmembrane protein 123
chr12_+_27623565 0.008 ENST00000535986.1
 SMCO2
single-pass membrane protein with coiled-coil domains 2
chr12_-_10251603 0.008 ENST00000457018.2
 CLEC1A
C-type lectin domain family 1, member A
chr7_-_107443652 0.008 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
 SLC26A3


solute carrier family 26 (anion exchanger), member 3


chr18_-_13915530 0.007 ENST00000327606.3
 MC2R
melanocortin 2 receptor (adrenocorticotropic hormone)
chr16_+_87636474 0.007 ENST00000284262.2
 JPH3
junctophilin 3
chr4_+_113152978 0.007 ENST00000309703.6
 AP1AR
adaptor-related protein complex 1 associated regulatory protein
chr14_-_90420862 0.007 ENST00000556005.1
ENST00000555872.1
 EFCAB11

EF-hand calcium binding domain 11

chr12_+_11905413 0.006 ENST00000545027.1
 ETV6
ets variant 6
chr1_+_185703513 0.006 ENST00000271588.4
ENST00000367492.2
 HMCN1

hemicentin 1

chr19_-_17375527 0.006 ENST00000431146.2
ENST00000594190.1
 USHBP1

Usher syndrome 1C binding protein 1

chr11_-_102323489 0.006 ENST00000361236.3
 TMEM123
transmembrane protein 123
chr1_+_244998602 0.006 ENST00000411948.2
 COX20
COX20 cytochrome C oxidase assembly factor
chr11_-_8964580 0.006 ENST00000325884.1
 ASCL3
achaete-scute family bHLH transcription factor 3
chr12_-_10251576 0.006 ENST00000315330.4
 CLEC1A
C-type lectin domain family 1, member A
chr18_+_7946941 0.005 ENST00000444013.1
 PTPRM
protein tyrosine phosphatase, receptor type, M
chr18_+_7946839 0.005 ENST00000578916.1
 PTPRM
protein tyrosine phosphatase, receptor type, M
chr10_+_35416223 0.005 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
 CREM





cAMP responsive element modulator





chr6_-_49712123 0.005 ENST00000263045.4
 CRISP3
cysteine-rich secretory protein 3
chr17_+_7323634 0.004 ENST00000323675.3
 SPEM1
spermatid maturation 1
chr20_-_5426332 0.004 ENST00000420529.1
 LINC00658
long intergenic non-protein coding RNA 658
chr20_+_30555805 0.004 ENST00000562532.2
 XKR7
XK, Kell blood group complex subunit-related family, member 7
chr11_+_128563948 0.004 ENST00000534087.2
 FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr14_-_90421028 0.003 ENST00000267544.9
ENST00000316738.7
ENST00000538485.2
ENST00000556609.1
 EFCAB11



EF-hand calcium binding domain 11



chr13_-_41593425 0.003 ENST00000239882.3
 ELF1
E74-like factor 1 (ets domain transcription factor)
chr5_-_117897751 0.003 ENST00000515704.1
ENST00000506769.1
 CTD-2281M20.1

CTD-2281M20.1

chr2_+_179184955 0.003 ENST00000315022.2
 OSBPL6
oxysterol binding protein-like 6
chr5_+_140739537 0.003 ENST00000522605.1
 PCDHGB2
protocadherin gamma subfamily B, 2
chr3_-_18466026 0.003 ENST00000417717.2
 SATB1
SATB homeobox 1
chr5_+_67588312 0.003 ENST00000519025.1
 PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr5_+_140787600 0.003 ENST00000520790.1
 PCDHGB6
protocadherin gamma subfamily B, 6
chr1_-_119532127 0.003 ENST00000207157.3
 TBX15
T-box 15
chr16_+_20499024 0.003 ENST00000593357.1
 AC137056.1
Uncharacterized protein; cDNA FLJ34659 fis, clone KIDNE2018863
chr14_+_101299520 0.002 ENST00000455531.1
 MEG3
maternally expressed 3 (non-protein coding)
chr5_+_135468516 0.002 ENST00000507118.1
ENST00000511116.1
ENST00000545279.1
ENST00000545620.1
 SMAD5



SMAD family member 5



chr20_-_45981138 0.002 ENST00000446994.2
 ZMYND8
zinc finger, MYND-type containing 8
chr17_-_10372875 0.002 ENST00000255381.2
 MYH4
myosin, heavy chain 4, skeletal muscle
chr7_-_11871815 0.002 ENST00000423059.4
 THSD7A
thrombospondin, type I, domain containing 7A
chr6_+_22146851 0.001 ENST00000606197.1
 CASC15
cancer susceptibility candidate 15 (non-protein coding)
chr15_+_76629064 0.001 ENST00000290759.4
 ISL2
ISL LIM homeobox 2
chr1_-_198906528 0.000 ENST00000432296.1
 MIR181A1HG
MIR181A1 host gene (non-protein coding)
chr8_+_24151620 0.000 ENST00000437154.2
 ADAM28
ADAM metallopeptidase domain 28

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0001300 chronological cell aging(GO:0001300)
0.0 0.1 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.1 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.0 0.0 GO:0006788 heme oxidation(GO:0006788)
0.0 0.0 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.2 GO:0070257 positive regulation of mucus secretion(GO:0070257)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.0 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 0.0 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)