Motif ID: SOX10_SOX15

Z-value: 0.382

Transcription factors associated with SOX10_SOX15:

Gene SymbolEntrez IDGene Name
SOX10 ENSG00000100146.12 SOX10
SOX15 ENSG00000129194.3 SOX15

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SOX10hg19_v2_chr22_-_38380543_383805690.491.8e-01Click!
SOX15hg19_v2_chr17_-_7493390_74934880.186.5e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of SOX10_SOX15

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_64029879 0.874 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
LGSN


lengsin, lens protein with glutamine synthetase domain


chr2_-_86564776 0.664 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
REEP1


receptor accessory protein 1


chrX_+_80457442 0.544 ENST00000373212.5
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr13_+_30002741 0.349 ENST00000380808.2
MTUS2
microtubule associated tumor suppressor candidate 2
chr13_+_30002846 0.340 ENST00000542829.1
MTUS2
microtubule associated tumor suppressor candidate 2
chr9_-_123476612 0.331 ENST00000426959.1
MEGF9
multiple EGF-like-domains 9
chr4_-_140477928 0.327 ENST00000274031.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr2_-_86564740 0.325 ENST00000540790.1
ENST00000428491.1
REEP1

receptor accessory protein 1

chr4_-_186877502 0.296 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
SORBS2


sorbin and SH3 domain containing 2


chr11_-_94965667 0.295 ENST00000542176.1
ENST00000278499.2
SESN3

sestrin 3

chr5_+_147258266 0.287 ENST00000296694.4
SCGB3A2
secretoglobin, family 3A, member 2
chr1_-_26233423 0.284 ENST00000357865.2
STMN1
stathmin 1
chr6_+_64282447 0.272 ENST00000370650.2
ENST00000578299.1
PTP4A1

protein tyrosine phosphatase type IVA, member 1

chr4_+_41614909 0.268 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1


LIM and calponin homology domains 1


chr2_-_1748214 0.255 ENST00000433670.1
ENST00000425171.1
ENST00000252804.4
PXDN


peroxidasin homolog (Drosophila)


chr2_-_37501692 0.233 ENST00000443977.1
PRKD3
protein kinase D3
chr4_-_140477910 0.224 ENST00000404104.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr5_+_43602750 0.206 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
NNT


nicotinamide nucleotide transhydrogenase


chr11_-_76155618 0.205 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr15_+_101402041 0.205 ENST00000558475.1
ENST00000558641.1
ENST00000559673.1
RP11-66B24.1


RP11-66B24.1


chr4_-_186732048 0.200 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2




sorbin and SH3 domain containing 2




chr9_-_123476719 0.190 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr12_+_8849773 0.188 ENST00000541044.1
RIMKLB
ribosomal modification protein rimK-like family member B
chr2_-_183387430 0.187 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr1_-_32801825 0.184 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr8_-_124553437 0.183 ENST00000517956.1
ENST00000443022.2
FBXO32

F-box protein 32

chr1_+_33722080 0.178 ENST00000483388.1
ENST00000539719.1
ZNF362

zinc finger protein 362

chrX_-_13956497 0.176 ENST00000398361.3
GPM6B
glycoprotein M6B
chr4_-_186877481 0.175 ENST00000444781.1
ENST00000432655.1
SORBS2

sorbin and SH3 domain containing 2

chr10_+_114710211 0.174 ENST00000349937.2
ENST00000369397.4
TCF7L2

transcription factor 7-like 2 (T-cell specific, HMG-box)

chr6_+_122720681 0.174 ENST00000368455.4
ENST00000452194.1
HSF2

heat shock transcription factor 2

chr20_+_61448376 0.174 ENST00000343916.3
COL9A3
collagen, type IX, alpha 3
chr6_+_72596604 0.172 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
RIMS1






regulating synaptic membrane exocytosis 1






chr15_-_52944231 0.168 ENST00000546305.2
FAM214A
family with sequence similarity 214, member A
chrX_-_106960285 0.164 ENST00000503515.1
ENST00000372397.2
TSC22D3

TSC22 domain family, member 3

chr3_-_167813672 0.164 ENST00000470487.1
GOLIM4
golgi integral membrane protein 4
chr12_-_8815215 0.162 ENST00000544889.1
ENST00000543369.1
MFAP5

microfibrillar associated protein 5

chr5_-_39424961 0.162 ENST00000503513.1
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr2_-_183387283 0.149 ENST00000435564.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr14_-_35099315 0.144 ENST00000396526.3
ENST00000396534.3
ENST00000355110.5
ENST00000557265.1
SNX6



sorting nexin 6



chr4_+_41614720 0.142 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr5_-_14871866 0.139 ENST00000284268.6
ANKH
ANKH inorganic pyrophosphate transport regulator
chr18_+_6729725 0.134 ENST00000400091.2
ENST00000583410.1
ENST00000584387.1
ARHGAP28


Rho GTPase activating protein 28


chr10_-_99030395 0.133 ENST00000355366.5
ENST00000371027.1
ARHGAP19

Rho GTPase activating protein 19

chr12_-_8815299 0.130 ENST00000535336.1
MFAP5
microfibrillar associated protein 5
chr20_+_33292068 0.130 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
TP53INP2


tumor protein p53 inducible nuclear protein 2


chr10_+_114709999 0.124 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
TCF7L2






transcription factor 7-like 2 (T-cell specific, HMG-box)






chr8_+_81398444 0.123 ENST00000455036.3
ENST00000426744.2
ZBTB10

zinc finger and BTB domain containing 10

chr18_+_6729698 0.118 ENST00000383472.4
ARHGAP28
Rho GTPase activating protein 28
chr5_+_43603229 0.116 ENST00000344920.4
ENST00000512996.2
NNT

nicotinamide nucleotide transhydrogenase

chr15_-_56035177 0.116 ENST00000389286.4
ENST00000561292.1
PRTG

protogenin

chr2_+_181845763 0.115 ENST00000602499.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr14_-_35099377 0.114 ENST00000362031.4
SNX6
sorting nexin 6
chr12_-_2966193 0.114 ENST00000382678.3
AC005841.1
Uncharacterized protein ENSP00000372125
chr8_-_18871159 0.114 ENST00000327040.8
ENST00000440756.2
PSD3

pleckstrin and Sec7 domain containing 3

chr2_+_181845843 0.113 ENST00000602710.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr11_+_36317830 0.112 ENST00000530639.1
PRR5L
proline rich 5 like
chr15_-_52043722 0.111 ENST00000454181.2
LYSMD2
LysM, putative peptidoglycan-binding, domain containing 2
chr15_+_57210961 0.111 ENST00000557843.1
TCF12
transcription factor 12
chr7_+_114055052 0.109 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2







forkhead box P2







chr5_-_65018834 0.108 ENST00000506816.1
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr11_-_130184555 0.108 ENST00000525842.1
ZBTB44
zinc finger and BTB domain containing 44
chr6_+_87865262 0.108 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292



zinc finger protein 292



chr4_-_186578674 0.107 ENST00000438278.1
SORBS2
sorbin and SH3 domain containing 2
chr2_-_47572105 0.105 ENST00000419035.1
ENST00000448713.1
ENST00000450550.1
ENST00000413185.2
AC073283.4



AC073283.4



chr20_+_6748311 0.104 ENST00000378827.4
BMP2
bone morphogenetic protein 2
chr13_+_98795434 0.102 ENST00000376586.2
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr7_+_116312411 0.102 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
MET


met proto-oncogene


chr1_-_6479963 0.102 ENST00000377836.4
ENST00000487437.1
ENST00000489730.1
ENST00000377834.4
HES2



hes family bHLH transcription factor 2



chr13_+_98795505 0.101 ENST00000319562.6
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr1_+_240255166 0.101 ENST00000319653.9
FMN2
formin 2
chr22_+_39052632 0.101 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
CBY1



chibby homolog 1 (Drosophila)



chr8_+_81397876 0.101 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr11_-_111781554 0.101 ENST00000526167.1
ENST00000528961.1
CRYAB

crystallin, alpha B

chr3_-_167813132 0.100 ENST00000309027.4
GOLIM4
golgi integral membrane protein 4
chr6_+_30848557 0.100 ENST00000460944.2
ENST00000324771.8
DDR1

discoidin domain receptor tyrosine kinase 1

chr1_-_79472365 0.099 ENST00000370742.3
ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
chr1_+_84767289 0.098 ENST00000394834.3
ENST00000370669.1
SAMD13

sterile alpha motif domain containing 13

chr11_+_126081662 0.097 ENST00000528985.1
ENST00000529731.1
ENST00000360194.4
ENST00000530043.1
FAM118B



family with sequence similarity 118, member B



chr10_-_61900762 0.097 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr14_-_91884150 0.096 ENST00000553403.1
CCDC88C
coiled-coil domain containing 88C
chr6_+_56911476 0.095 ENST00000545356.1
KIAA1586
KIAA1586
chrX_-_131352152 0.094 ENST00000342983.2
RAP2C
RAP2C, member of RAS oncogene family
chr3_+_183353356 0.094 ENST00000242810.6
ENST00000493074.1
ENST00000437402.1
ENST00000454495.2
ENST00000473045.1
ENST00000468101.1
ENST00000427201.2
ENST00000482138.1
ENST00000454652.2
KLHL24








kelch-like family member 24








chr6_+_149068464 0.092 ENST00000367463.4
UST
uronyl-2-sulfotransferase
chr13_+_98795664 0.091 ENST00000376581.5
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr3_-_48470838 0.090 ENST00000358459.4
ENST00000358536.4
PLXNB1

plexin B1

chr5_-_175964366 0.090 ENST00000274811.4
RNF44
ring finger protein 44
chr17_+_29815013 0.090 ENST00000394744.2
RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr8_+_61822605 0.088 ENST00000526936.1
AC022182.1
AC022182.1
chr15_+_85144217 0.088 ENST00000540936.1
ENST00000448803.2
ENST00000546275.1
ENST00000546148.1
ENST00000442073.3
ENST00000334141.3
ENST00000358472.3
ENST00000502939.2
ENST00000379358.3
ENST00000327179.6
ZSCAN2









zinc finger and SCAN domain containing 2









chr10_-_99393208 0.088 ENST00000307450.6
MORN4
MORN repeat containing 4
chr11_-_130184470 0.086 ENST00000357899.4
ENST00000397753.1
ZBTB44

zinc finger and BTB domain containing 44

chr20_-_20693131 0.085 ENST00000202677.7
RALGAPA2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr5_-_111093167 0.083 ENST00000446294.2
ENST00000419114.2
NREP

neuronal regeneration related protein

chr10_+_35415978 0.083 ENST00000429130.3
ENST00000469949.2
ENST00000460270.1
CREM


cAMP responsive element modulator


chr5_+_159848807 0.083 ENST00000352433.5
PTTG1
pituitary tumor-transforming 1
chr17_+_36861735 0.083 ENST00000378137.5
ENST00000325718.7
MLLT6

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6

chr5_-_111093081 0.083 ENST00000453526.2
ENST00000509427.1
NREP

neuronal regeneration related protein

chr5_+_78532003 0.082 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr18_-_22932080 0.082 ENST00000584787.1
ENST00000361524.3
ENST00000538137.2
ZNF521


zinc finger protein 521


chr2_+_74685527 0.081 ENST00000393972.3
ENST00000409737.1
ENST00000428943.1
WBP1


WW domain binding protein 1


chr7_+_30174668 0.081 ENST00000415604.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr9_-_74383302 0.080 ENST00000377066.5
TMEM2
transmembrane protein 2
chr5_-_65017921 0.079 ENST00000381007.4
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr12_+_124997766 0.079 ENST00000543970.1
RP11-83B20.1
RP11-83B20.1
chr7_+_30185406 0.078 ENST00000324489.5
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr5_-_111092930 0.075 ENST00000257435.7
NREP
neuronal regeneration related protein
chr8_-_17579726 0.075 ENST00000381861.3
MTUS1
microtubule associated tumor suppressor 1
chr3_-_129513259 0.075 ENST00000329333.5
TMCC1
transmembrane and coiled-coil domain family 1
chr6_+_74405501 0.075 ENST00000437994.2
ENST00000422508.2
CD109

CD109 molecule

chr12_-_105478339 0.074 ENST00000424857.2
ENST00000258494.9
ALDH1L2

aldehyde dehydrogenase 1 family, member L2

chr7_-_99869799 0.074 ENST00000436886.2
GATS
GATS, stromal antigen 3 opposite strand
chr11_-_111781454 0.074 ENST00000533280.1
CRYAB
crystallin, alpha B
chrX_-_21776281 0.072 ENST00000379494.3
SMPX
small muscle protein, X-linked
chr1_+_93645314 0.072 ENST00000343253.7
CCDC18
coiled-coil domain containing 18
chr5_-_138718973 0.071 ENST00000353963.3
ENST00000348729.3
SLC23A1

solute carrier family 23 (ascorbic acid transporter), member 1

chr5_-_58571935 0.070 ENST00000503258.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_-_200992827 0.070 ENST00000332129.2
ENST00000422435.2
KIF21B

kinesin family member 21B

chr12_-_71551868 0.069 ENST00000247829.3
TSPAN8
tetraspanin 8
chr22_-_39052300 0.068 ENST00000355830.6
FAM227A
family with sequence similarity 227, member A
chr6_+_74405804 0.068 ENST00000287097.5
CD109
CD109 molecule
chr5_+_138089100 0.068 ENST00000520339.1
ENST00000355078.5
ENST00000302763.7
ENST00000518910.1
CTNNA1



catenin (cadherin-associated protein), alpha 1, 102kDa



chr3_-_141747950 0.068 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr2_-_179343226 0.067 ENST00000434643.2
FKBP7
FK506 binding protein 7
chr17_-_7590745 0.067 ENST00000514944.1
ENST00000503591.1
ENST00000455263.2
ENST00000420246.2
ENST00000445888.2
ENST00000509690.1
ENST00000604348.1
ENST00000269305.4
TP53







tumor protein p53







chr6_-_134861089 0.067 ENST00000606039.1
RP11-557H15.4
RP11-557H15.4
chr6_-_75912508 0.066 ENST00000416123.2
COL12A1
collagen, type XII, alpha 1
chr8_-_38386175 0.066 ENST00000437935.2
ENST00000358138.1
C8orf86

chromosome 8 open reading frame 86

chr11_-_111781610 0.066 ENST00000525823.1
CRYAB
crystallin, alpha B
chr12_-_71003568 0.065 ENST00000547715.1
ENST00000451516.2
ENST00000538708.1
ENST00000550857.1
ENST00000261266.5
PTPRB




protein tyrosine phosphatase, receptor type, B




chr2_+_74685413 0.064 ENST00000233615.2
WBP1
WW domain binding protein 1
chr6_-_79944336 0.062 ENST00000344726.5
ENST00000275036.7
HMGN3

high mobility group nucleosomal binding domain 3

chrX_-_117107542 0.062 ENST00000371878.1
KLHL13
kelch-like family member 13
chr6_+_101846664 0.062 ENST00000421544.1
ENST00000413795.1
ENST00000369138.1
ENST00000358361.3
GRIK2



glutamate receptor, ionotropic, kainate 2



chr3_-_188665428 0.062 ENST00000444488.1
TPRG1-AS1
TPRG1 antisense RNA 1
chr4_-_170192185 0.061 ENST00000284637.9
SH3RF1
SH3 domain containing ring finger 1
chr1_+_180601139 0.061 ENST00000367590.4
ENST00000367589.3
XPR1

xenotropic and polytropic retrovirus receptor 1

chr10_+_35415719 0.060 ENST00000474362.1
ENST00000374721.3
CREM

cAMP responsive element modulator

chr5_-_137090028 0.060 ENST00000314940.4
HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr12_-_102591604 0.060 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr12_-_118498911 0.060 ENST00000544233.1
WSB2
WD repeat and SOCS box containing 2
chr16_+_23765948 0.059 ENST00000300113.2
CHP2
calcineurin-like EF-hand protein 2
chr3_-_157221128 0.058 ENST00000392833.2
ENST00000362010.2
VEPH1

ventricular zone expressed PH domain-containing 1

chr8_+_81397846 0.057 ENST00000379091.4
ZBTB10
zinc finger and BTB domain containing 10
chr2_-_165697717 0.057 ENST00000439313.1
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr2_-_179343268 0.057 ENST00000424785.2
FKBP7
FK506 binding protein 7
chr17_-_62050278 0.057 ENST00000578147.1
ENST00000435607.1
SCN4A

sodium channel, voltage-gated, type IV, alpha subunit

chr6_+_30848740 0.056 ENST00000505534.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr11_-_8892464 0.056 ENST00000527347.1
ENST00000526241.1
ENST00000526126.1
ENST00000530938.1
ENST00000526057.1
ST5




suppression of tumorigenicity 5




chr6_-_165989936 0.056 ENST00000354448.4
PDE10A
phosphodiesterase 10A
chr10_+_123923205 0.056 ENST00000369004.3
ENST00000260733.3
TACC2

transforming, acidic coiled-coil containing protein 2

chr2_-_163099885 0.055 ENST00000443424.1
FAP
fibroblast activation protein, alpha
chr4_-_164534657 0.055 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr5_+_137514834 0.055 ENST00000508792.1
ENST00000504621.1
KIF20A

kinesin family member 20A

chr3_-_79816965 0.055 ENST00000464233.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr16_+_53483983 0.055 ENST00000544545.1
RBL2
retinoblastoma-like 2 (p130)
chr5_-_146435501 0.054 ENST00000336640.6
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr4_-_186732241 0.054 ENST00000421639.1
SORBS2
sorbin and SH3 domain containing 2
chr2_-_39348137 0.054 ENST00000426016.1
SOS1
son of sevenless homolog 1 (Drosophila)
chr7_-_32111009 0.054 ENST00000396184.3
ENST00000396189.2
ENST00000321453.7
PDE1C


phosphodiesterase 1C, calmodulin-dependent 70kDa


chr6_+_30848771 0.052 ENST00000503180.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr12_-_118498958 0.052 ENST00000315436.3
WSB2
WD repeat and SOCS box containing 2
chr5_+_137514687 0.052 ENST00000394894.3
KIF20A
kinesin family member 20A
chr5_+_65222438 0.052 ENST00000380938.2
ERBB2IP
erbb2 interacting protein
chr5_-_146435572 0.052 ENST00000394414.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr18_-_45456693 0.052 ENST00000587421.1
SMAD2
SMAD family member 2
chr18_+_72201829 0.051 ENST00000582365.1
CNDP1
carnosine dipeptidase 1 (metallopeptidase M20 family)
chr5_-_141338377 0.051 ENST00000510041.1
PCDH12
protocadherin 12
chr9_+_96846740 0.051 ENST00000288976.3
PTPDC1
protein tyrosine phosphatase domain containing 1
chr10_-_99094458 0.051 ENST00000371019.2
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr1_+_47799542 0.050 ENST00000471289.2
ENST00000450808.2
CMPK1

cytidine monophosphate (UMP-CMP) kinase 1, cytosolic

chr10_+_35484793 0.050 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM




cAMP responsive element modulator




chr15_+_77224045 0.049 ENST00000320963.5
ENST00000394883.3
RCN2

reticulocalbin 2, EF-hand calcium binding domain

chr12_-_31477072 0.049 ENST00000454658.2
FAM60A
family with sequence similarity 60, member A
chr19_-_10047219 0.048 ENST00000264833.4
OLFM2
olfactomedin 2
chr5_+_137514403 0.048 ENST00000513276.1
KIF20A
kinesin family member 20A
chr13_-_24007815 0.048 ENST00000382298.3
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr1_+_228337553 0.047 ENST00000366714.2
GJC2
gap junction protein, gamma 2, 47kDa
chr5_-_111092873 0.047 ENST00000509025.1
ENST00000515855.1
NREP

neuronal regeneration related protein

chr18_-_74207146 0.047 ENST00000443185.2
ZNF516
zinc finger protein 516
chr4_+_154178520 0.047 ENST00000433687.1
TRIM2
tripartite motif containing 2
chr11_-_117166276 0.046 ENST00000510630.1
ENST00000392937.6
BACE1

beta-site APP-cleaving enzyme 1

chr4_+_144303093 0.046 ENST00000505913.1
GAB1
GRB2-associated binding protein 1
chr17_+_21730180 0.046 ENST00000584398.1
UBBP4
ubiquitin B pseudogene 4
chr1_+_93913713 0.046 ENST00000604705.1
ENST00000370253.2
FNBP1L

formin binding protein 1-like

chr16_-_73082274 0.046 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chr3_+_119814070 0.045 ENST00000469070.1
RP11-18H7.1
RP11-18H7.1
chr5_-_146435694 0.045 ENST00000356826.3
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr21_+_35553045 0.044 ENST00000416145.1
ENST00000430922.1
ENST00000419881.2
LINC00310


long intergenic non-protein coding RNA 310


chr1_-_228603694 0.044 ENST00000366697.2
TRIM17
tripartite motif containing 17
chr1_-_108231101 0.044 ENST00000544443.1
ENST00000415432.2
VAV3

vav 3 guanine nucleotide exchange factor

chr10_-_99393242 0.044 ENST00000370635.3
ENST00000478953.1
ENST00000335628.3
MORN4


MORN repeat containing 4


chr14_+_77228532 0.044 ENST00000167106.4
ENST00000554237.1
VASH1

vasohibin 1

chr19_-_49864746 0.043 ENST00000598810.1
TEAD2
TEA domain family member 2
chr11_+_46402744 0.043 ENST00000533952.1
MDK
midkine (neurite growth-promoting factor 2)
chr13_+_37393351 0.043 ENST00000255476.2
RFXAP
regulatory factor X-associated protein
chr16_-_22385901 0.043 ENST00000268383.2
CDR2
cerebellar degeneration-related protein 2, 62kDa
chr2_-_67442409 0.042 ENST00000414404.1
ENST00000433133.1
AC078941.1

AC078941.1

chr17_+_19030782 0.042 ENST00000344415.4
ENST00000577213.1
GRAPL

GRB2-related adaptor protein-like


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.3 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.4 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.3 GO:0006740 NADPH regeneration(GO:0006740)
0.0 1.0 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.3 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.6 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0060129 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) regulation of calcium-independent cell-cell adhesion(GO:0051040) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.3 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.1 GO:1903450 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.0 0.2 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.1 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.4 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:1902362 melanocyte apoptotic process(GO:1902362)
0.0 0.2 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.1 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.8 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.1 GO:0097252 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.0 0.1 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0 0.1 GO:0030421 defecation(GO:0030421)
0.0 0.1 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.0 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.0 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0 0.0 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.0 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.0 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.0 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.1 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.0 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.0 0.1 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.0 GO:1900276 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.3 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907)
0.0 0.3 GO:0097422 tubular endosome(GO:0097422)
0.0 1.0 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.1 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.0 GO:0072517 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 1.0 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.3 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.2 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.1 0.3 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.3 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.0 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.0 0.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 0.0 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)