Motif ID: SMAD4

Z-value: 1.242


Transcription factors associated with SMAD4:

Gene SymbolEntrez IDGene Name
SMAD4 ENSG00000141646.9 SMAD4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SMAD4hg19_v2_chr18_+_48556470_48556640-0.781.3e-02Click!


Activity profile for motif SMAD4.

activity profile for motif SMAD4


Sorted Z-values histogram for motif SMAD4

Sorted Z-values for motif SMAD4



Network of associatons between targets according to the STRING database.



First level regulatory network of SMAD4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_8815215 2.102 ENST00000544889.1
ENST00000543369.1
MFAP5

microfibrillar associated protein 5

chr22_+_31518938 1.798 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J






inositol polyphosphate-5-phosphatase J






chr12_-_8815299 1.645 ENST00000535336.1
MFAP5
microfibrillar associated protein 5
chr1_-_151345159 1.164 ENST00000458566.1
ENST00000447402.3
ENST00000426705.2
ENST00000435071.1
ENST00000368868.5
SELENBP1




selenium binding protein 1




chr2_-_228028829 1.086 ENST00000396625.3
ENST00000329662.7
COL4A4

collagen, type IV, alpha 4

chr6_-_87804815 1.079 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr9_+_72658490 1.045 ENST00000377182.4
MAMDC2
MAM domain containing 2
chr22_+_30752606 1.030 ENST00000399824.2
ENST00000405659.1
ENST00000338306.3
CCDC157


coiled-coil domain containing 157


chrX_-_99987088 1.027 ENST00000372981.1
ENST00000263033.5
SYTL4

synaptotagmin-like 4

chr5_-_121413974 1.008 ENST00000231004.4
LOX
lysyl oxidase
chr15_+_49715449 0.917 ENST00000560979.1
FGF7
fibroblast growth factor 7
chr15_+_49715293 0.896 ENST00000267843.4
ENST00000560270.1
FGF7

fibroblast growth factor 7

chr10_+_18689637 0.893 ENST00000377315.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr20_+_57766075 0.872 ENST00000371030.2
ZNF831
zinc finger protein 831
chr1_+_26485511 0.831 ENST00000374268.3
FAM110D
family with sequence similarity 110, member D
chr8_+_145726472 0.796 ENST00000528430.1
PPP1R16A
protein phosphatase 1, regulatory subunit 16A
chr10_+_88718397 0.786 ENST00000372017.3
SNCG
synuclein, gamma (breast cancer-specific protein 1)
chr3_+_9958758 0.738 ENST00000383812.4
ENST00000438091.1
ENST00000295981.3
ENST00000436503.1
ENST00000403601.3
ENST00000416074.2
ENST00000455057.1
IL17RC






interleukin 17 receptor C






chr10_+_88718314 0.737 ENST00000348795.4
SNCG
synuclein, gamma (breast cancer-specific protein 1)
chr2_+_233385173 0.700 ENST00000449534.2
PRSS56
protease, serine, 56
chr1_-_151798546 0.695 ENST00000356728.6
RORC
RAR-related orphan receptor C
chr12_-_772901 0.674 ENST00000305108.4
NINJ2
ninjurin 2
chr4_-_186697044 0.673 ENST00000437304.2
SORBS2
sorbin and SH3 domain containing 2
chr4_+_40337340 0.643 ENST00000310169.2
CHRNA9
cholinergic receptor, nicotinic, alpha 9 (neuronal)
chr12_+_53443963 0.617 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1


tensin like C1 domain containing phosphatase (tensin 2)


chr19_+_49617609 0.614 ENST00000221459.2
ENST00000486217.2
LIN7B

lin-7 homolog B (C. elegans)

chr16_+_812506 0.604 ENST00000569566.1
MSLN
mesothelin
chr11_-_61596753 0.604 ENST00000448607.1
ENST00000421879.1
FADS1

fatty acid desaturase 1

chr6_+_30850862 0.582 ENST00000504651.1
ENST00000512694.1
ENST00000515233.1
DDR1


discoidin domain receptor tyrosine kinase 1


chr11_-_1776176 0.578 ENST00000429746.1
CTSD
cathepsin D
chr5_-_111092930 0.576 ENST00000257435.7
NREP
neuronal regeneration related protein
chr19_+_3708376 0.545 ENST00000539908.2
TJP3
tight junction protein 3
chr11_-_17555421 0.533 ENST00000526181.1
USH1C
Usher syndrome 1C (autosomal recessive, severe)
chr14_-_92413353 0.529 ENST00000556154.1
FBLN5
fibulin 5
chr12_-_6740802 0.522 ENST00000431922.1
LPAR5
lysophosphatidic acid receptor 5
chr13_-_40177261 0.516 ENST00000379589.3
LHFP
lipoma HMGIC fusion partner
chr17_-_34122596 0.516 ENST00000250144.8
MMP28
matrix metallopeptidase 28
chr11_-_67120974 0.516 ENST00000539074.1
ENST00000312419.3
POLD4

polymerase (DNA-directed), delta 4, accessory subunit

chr4_-_186696636 0.513 ENST00000444771.1
SORBS2
sorbin and SH3 domain containing 2
chr11_+_66742742 0.510 ENST00000308963.4
C11orf86
chromosome 11 open reading frame 86
chr2_+_130939827 0.501 ENST00000409255.1
ENST00000455239.1
MZT2B

mitotic spindle organizing protein 2B

chr9_-_139891165 0.499 ENST00000494426.1
CLIC3
chloride intracellular channel 3
chr19_-_44285401 0.498 ENST00000262888.3
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr8_-_144890847 0.497 ENST00000531942.1
SCRIB
scribbled planar cell polarity protein
chr1_-_238649319 0.493 ENST00000400946.2
RP11-371I1.2
long intergenic non-protein coding RNA 1139
chr3_+_100211412 0.492 ENST00000323523.4
ENST00000403410.1
ENST00000449609.1
TMEM45A


transmembrane protein 45A


chr21_+_45725050 0.490 ENST00000403390.1
PFKL
phosphofructokinase, liver
chr2_-_218867711 0.477 ENST00000446903.1
TNS1
tensin 1
chr3_+_9958870 0.477 ENST00000413608.1
IL17RC
interleukin 17 receptor C
chr5_-_111093340 0.476 ENST00000508870.1
NREP
neuronal regeneration related protein
chr3_+_154797877 0.473 ENST00000462745.1
ENST00000493237.1
MME

membrane metallo-endopeptidase

chr19_-_47231216 0.473 ENST00000594287.2
STRN4
striatin, calmodulin binding protein 4
chr15_+_75182346 0.469 ENST00000569931.1
ENST00000352410.4
ENST00000566377.1
ENST00000569233.1
ENST00000567132.1
ENST00000564633.1
ENST00000568907.1
ENST00000563422.1
ENST00000564003.1
ENST00000562800.1
ENST00000563786.1
ENST00000535694.1
ENST00000323744.6
ENST00000568828.1
ENST00000562606.1
ENST00000565576.1
ENST00000567570.1
MPI
















mannose phosphate isomerase
















chr18_+_11851383 0.466 ENST00000526991.2
CHMP1B
charged multivesicular body protein 1B
chr14_+_21156915 0.465 ENST00000397990.4
ENST00000555597.1
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr11_-_568369 0.462 ENST00000534540.1
ENST00000528245.1
ENST00000500447.1
ENST00000533920.1
MIR210HG



MIR210 host gene (non-protein coding)



chr19_+_7580944 0.462 ENST00000597229.1
ZNF358
zinc finger protein 358
chr13_+_31309645 0.458 ENST00000380490.3
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr19_-_3557401 0.457 ENST00000389395.3
ENST00000398558.4
MFSD12

major facilitator superfamily domain containing 12

chr17_+_41476327 0.455 ENST00000320033.4
ARL4D
ADP-ribosylation factor-like 4D
chr14_-_103989033 0.451 ENST00000553878.1
ENST00000557530.1
CKB

creatine kinase, brain

chr11_+_67777751 0.446 ENST00000316367.6
ENST00000007633.8
ENST00000342456.6
ALDH3B1


aldehyde dehydrogenase 3 family, member B1


chr3_+_154798162 0.445 ENST00000360490.2
MME
membrane metallo-endopeptidase
chr12_-_54779511 0.445 ENST00000551109.1
ENST00000546970.1
ZNF385A

zinc finger protein 385A

chr16_+_58059470 0.444 ENST00000219271.3
MMP15
matrix metallopeptidase 15 (membrane-inserted)
chr5_-_111093406 0.439 ENST00000379671.3
NREP
neuronal regeneration related protein
chr6_+_43027595 0.433 ENST00000259708.3
ENST00000472792.1
ENST00000479388.1
ENST00000460283.1
ENST00000394056.2
KLC4




kinesin light chain 4




chr19_-_7553852 0.433 ENST00000593547.1
PEX11G
peroxisomal biogenesis factor 11 gamma
chr19_-_6720686 0.430 ENST00000245907.6
C3
complement component 3
chr17_-_39942322 0.430 ENST00000449889.1
ENST00000465293.1
JUP

junction plakoglobin

chr8_-_144660485 0.425 ENST00000276844.7
ENST00000340490.3
ENST00000435154.3
ENST00000426292.3
NAPRT1



nicotinate phosphoribosyltransferase domain containing 1



chr22_-_24241117 0.422 ENST00000406213.1
AP000350.4
Uncharacterized protein
chr11_-_8739566 0.419 ENST00000533020.1
ST5
suppression of tumorigenicity 5
chr16_-_31076273 0.418 ENST00000426488.2
ZNF668
zinc finger protein 668
chr5_-_111093081 0.412 ENST00000453526.2
ENST00000509427.1
NREP

neuronal regeneration related protein

chr17_+_18128896 0.409 ENST00000316843.4
LLGL1
lethal giant larvae homolog 1 (Drosophila)
chr6_+_30850697 0.406 ENST00000509639.1
ENST00000412274.2
ENST00000507901.1
ENST00000507046.1
ENST00000437124.2
ENST00000454612.2
ENST00000396342.2
DDR1






discoidin domain receptor tyrosine kinase 1






chr19_+_3708338 0.406 ENST00000590545.1
TJP3
tight junction protein 3
chr12_-_54778471 0.403 ENST00000550120.1
ENST00000394313.2
ENST00000547210.1
ZNF385A


zinc finger protein 385A


chr16_-_31076332 0.396 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
ZNF668


zinc finger protein 668


chr12_-_8025442 0.396 ENST00000340749.5
ENST00000535295.1
ENST00000539234.1
SLC2A14


solute carrier family 2 (facilitated glucose transporter), member 14


chr1_+_228337553 0.395 ENST00000366714.2
GJC2
gap junction protein, gamma 2, 47kDa
chr2_-_209118974 0.392 ENST00000415913.1
ENST00000415282.1
ENST00000446179.1
IDH1


isocitrate dehydrogenase 1 (NADP+), soluble


chr5_+_66124590 0.390 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
MAST4


microtubule associated serine/threonine kinase family member 4


chr18_+_44526786 0.388 ENST00000245121.5
ENST00000356157.7
KATNAL2

katanin p60 subunit A-like 2

chr6_-_112080256 0.385 ENST00000462856.2
ENST00000229471.4
FYN

FYN oncogene related to SRC, FGR, YES

chr19_-_18709357 0.378 ENST00000597131.1
CRLF1
cytokine receptor-like factor 1
chr5_+_147443534 0.378 ENST00000398454.1
ENST00000359874.3
ENST00000508733.1
ENST00000256084.7
SPINK5



serine peptidase inhibitor, Kazal type 5



chr19_-_17958832 0.376 ENST00000458235.1
JAK3
Janus kinase 3
chr12_+_53443680 0.375 ENST00000314250.6
ENST00000451358.1
TENC1

tensin like C1 domain containing phosphatase (tensin 2)

chr11_+_76493294 0.375 ENST00000533752.1
TSKU
tsukushi, small leucine rich proteoglycan
chr6_-_43197189 0.372 ENST00000509253.1
ENST00000393987.2
ENST00000230431.6
DNPH1


2'-deoxynucleoside 5'-phosphate N-hydrolase 1


chr4_+_926214 0.371 ENST00000514453.1
ENST00000515492.1
ENST00000509508.1
ENST00000515740.1
ENST00000508204.1
ENST00000510493.1
ENST00000514546.1
TMEM175






transmembrane protein 175






chr11_-_62474803 0.369 ENST00000533982.1
ENST00000360796.5
BSCL2

Berardinelli-Seip congenital lipodystrophy 2 (seipin)

chr19_+_5690297 0.365 ENST00000582463.1
ENST00000579446.1
ENST00000394580.2
RPL36


ribosomal protein L36


chr17_+_36886478 0.363 ENST00000439660.2
CISD3
CDGSH iron sulfur domain 3
chr9_-_130635741 0.359 ENST00000223836.10
AK1
adenylate kinase 1
chr11_-_111794446 0.358 ENST00000527950.1
CRYAB
crystallin, alpha B
chr19_-_46285736 0.357 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
DMPK


dystrophia myotonica-protein kinase


chr20_+_48789087 0.356 ENST00000427333.1
RP11-112L6.4
RP11-112L6.4
chr17_+_48172639 0.355 ENST00000503176.1
ENST00000503614.1
PDK2

pyruvate dehydrogenase kinase, isozyme 2

chr20_+_30193083 0.354 ENST00000376112.3
ENST00000376105.3
ID1

inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

chr18_+_21572737 0.352 ENST00000304621.6
TTC39C
tetratricopeptide repeat domain 39C
chr12_-_54778444 0.350 ENST00000551771.1
ZNF385A
zinc finger protein 385A
chr14_+_21538429 0.348 ENST00000298694.4
ENST00000555038.1
ARHGEF40

Rho guanine nucleotide exchange factor (GEF) 40

chr2_+_95963052 0.348 ENST00000295225.5
KCNIP3
Kv channel interacting protein 3, calsenilin
chr2_-_85108363 0.347 ENST00000335459.5
TRABD2A
TraB domain containing 2A
chr8_-_145743164 0.346 ENST00000428558.2
RECQL4
RecQ protein-like 4
chr12_-_8025499 0.345 ENST00000431042.2
SLC2A14
solute carrier family 2 (facilitated glucose transporter), member 14
chr19_-_46285646 0.344 ENST00000458663.2
DMPK
dystrophia myotonica-protein kinase
chr11_-_61647935 0.341 ENST00000531956.1
FADS3
fatty acid desaturase 3
chr19_+_507299 0.340 ENST00000359315.5
TPGS1
tubulin polyglutamylase complex subunit 1
chr9_+_34652164 0.339 ENST00000441545.2
ENST00000553620.1
IL11RA

interleukin 11 receptor, alpha

chr1_-_44482979 0.339 ENST00000360584.2
ENST00000357730.2
ENST00000528803.1
SLC6A9


solute carrier family 6 (neurotransmitter transporter, glycine), member 9


chr19_+_5690207 0.338 ENST00000347512.3
RPL36
ribosomal protein L36
chr19_-_7553889 0.335 ENST00000221480.1
PEX11G
peroxisomal biogenesis factor 11 gamma
chr10_+_81838411 0.333 ENST00000372281.3
ENST00000372277.3
ENST00000372275.1
ENST00000372274.1
TMEM254



transmembrane protein 254



chr19_-_49371711 0.333 ENST00000355496.5
ENST00000263265.6
PLEKHA4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

chr12_-_6484715 0.332 ENST00000228916.2
SCNN1A
sodium channel, non-voltage-gated 1 alpha subunit
chr11_-_67276100 0.330 ENST00000301488.3
CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr5_+_177540444 0.329 ENST00000274605.5
N4BP3
NEDD4 binding protein 3
chrX_+_102631248 0.328 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
NGFRAP1


nerve growth factor receptor (TNFRSF16) associated protein 1


chr2_-_85108164 0.328 ENST00000409520.2
TRABD2A
TraB domain containing 2A
chr9_-_131644306 0.328 ENST00000302586.3
CCBL1
cysteine conjugate-beta lyase, cytoplasmic
chr17_-_7761256 0.323 ENST00000575208.1
LSMD1
LSM domain containing 1
chr2_-_154335300 0.323 ENST00000325926.3
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr1_-_44497024 0.321 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
SLC6A9


solute carrier family 6 (neurotransmitter transporter, glycine), member 9


chr20_-_57582296 0.319 ENST00000217131.5
CTSZ
cathepsin Z
chr19_-_41222775 0.318 ENST00000324464.3
ENST00000450541.1
ENST00000594720.1
ADCK4


aarF domain containing kinase 4


chr6_-_31612808 0.317 ENST00000438149.1
BAG6
BCL2-associated athanogene 6
chr11_+_65408273 0.317 ENST00000394227.3
SIPA1
signal-induced proliferation-associated 1
chr19_-_46148820 0.317 ENST00000587152.1
EML2
echinoderm microtubule associated protein like 2
chr12_-_91572278 0.315 ENST00000425043.1
ENST00000420120.2
ENST00000441303.2
ENST00000456569.2
DCN



decorin



chr10_+_26727125 0.314 ENST00000376236.4
APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr19_-_50143452 0.314 ENST00000246792.3
RRAS
related RAS viral (r-ras) oncogene homolog
chr12_-_8025398 0.313 ENST00000535344.1
ENST00000543909.1
SLC2A14

solute carrier family 2 (facilitated glucose transporter), member 14

chr19_-_42463418 0.312 ENST00000600292.1
ENST00000601078.1
ENST00000601891.1
ENST00000222008.6
RABAC1



Rab acceptor 1 (prenylated)



chr10_+_81838792 0.310 ENST00000372273.3
TMEM254
transmembrane protein 254
chr19_-_17958771 0.304 ENST00000534444.1
JAK3
Janus kinase 3
chr19_+_49617581 0.303 ENST00000391864.3
LIN7B
lin-7 homolog B (C. elegans)
chr22_+_50639408 0.303 ENST00000380903.2
SELO
Selenoprotein O
chr19_+_40873617 0.302 ENST00000599353.1
PLD3
phospholipase D family, member 3
chr17_-_7760779 0.301 ENST00000335155.5
ENST00000575071.1
LSMD1

LSM domain containing 1

chr11_-_93271058 0.300 ENST00000527149.1
SMCO4
single-pass membrane protein with coiled-coil domains 4
chr12_-_6484376 0.300 ENST00000360168.3
ENST00000358945.3
SCNN1A

sodium channel, non-voltage-gated 1 alpha subunit

chr11_+_62496114 0.296 ENST00000532583.1
TTC9C
tetratricopeptide repeat domain 9C
chr3_-_48632593 0.296 ENST00000454817.1
ENST00000328333.8
COL7A1

collagen, type VII, alpha 1

chr17_-_39780634 0.293 ENST00000577817.2
KRT17
keratin 17
chr11_-_3186494 0.293 ENST00000389989.3
ENST00000542243.1
OSBPL5

oxysterol binding protein-like 5

chr7_-_150777920 0.290 ENST00000353841.2
ENST00000297532.6
FASTK

Fas-activated serine/threonine kinase

chr19_-_45953983 0.290 ENST00000592083.1
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr12_-_6483969 0.288 ENST00000396966.2
SCNN1A
sodium channel, non-voltage-gated 1 alpha subunit
chr7_-_150777874 0.288 ENST00000540185.1
FASTK
Fas-activated serine/threonine kinase
chrX_+_102631844 0.287 ENST00000372634.1
ENST00000299872.7
NGFRAP1

nerve growth factor receptor (TNFRSF16) associated protein 1

chr4_+_926171 0.287 ENST00000507319.1
ENST00000264771.4
TMEM175

transmembrane protein 175

chr7_-_16872932 0.286 ENST00000419572.2
ENST00000412973.1
AGR2

anterior gradient 2

chr20_+_43343517 0.286 ENST00000372865.4
WISP2
WNT1 inducible signaling pathway protein 2
chr14_+_21152259 0.282 ENST00000336811.6
ENST00000555835.1
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr8_+_144679984 0.281 ENST00000504548.2
ENST00000321385.3
TIGD5

tigger transposable element derived 5

chr17_+_79968655 0.281 ENST00000583744.1
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr16_-_28550348 0.280 ENST00000324873.6
NUPR1
nuclear protein, transcriptional regulator, 1
chr1_-_147245484 0.278 ENST00000271348.2
GJA5
gap junction protein, alpha 5, 40kDa
chr17_+_54671047 0.277 ENST00000332822.4
NOG
noggin
chr2_-_209119831 0.276 ENST00000345146.2
IDH1
isocitrate dehydrogenase 1 (NADP+), soluble
chr16_-_71918033 0.274 ENST00000425432.1
ENST00000313565.6
ENST00000568666.1
ENST00000562797.1
ENST00000564134.1
ZNF821




zinc finger protein 821




chr16_+_57702210 0.273 ENST00000450388.3
GPR97
G protein-coupled receptor 97
chr2_+_234296792 0.273 ENST00000409813.3
DGKD
diacylglycerol kinase, delta 130kDa
chr16_+_616995 0.273 ENST00000293874.2
ENST00000409527.2
ENST00000424439.2
ENST00000540585.1
PIGQ

NHLRC4

phosphatidylinositol glycan anchor biosynthesis, class Q

NHL repeat containing 4

chr20_+_43343476 0.273 ENST00000372868.2
WISP2
WNT1 inducible signaling pathway protein 2
chr17_-_40828969 0.271 ENST00000591022.1
ENST00000587627.1
ENST00000293349.6
PLEKHH3


pleckstrin homology domain containing, family H (with MyTH4 domain) member 3


chr19_+_52076425 0.271 ENST00000436511.2
ZNF175
zinc finger protein 175
chr9_+_118950325 0.271 ENST00000534838.1
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr9_-_139948468 0.271 ENST00000312665.5
ENTPD2
ectonucleoside triphosphate diphosphohydrolase 2
chr3_+_52017454 0.270 ENST00000476854.1
ENST00000476351.1
ENST00000494103.1
ENST00000404366.2
ENST00000469863.1
ACY1




aminoacylase 1




chr19_+_41117770 0.269 ENST00000601032.1
LTBP4
latent transforming growth factor beta binding protein 4
chr22_-_51066521 0.268 ENST00000395621.3
ENST00000395619.3
ENST00000356098.5
ENST00000216124.5
ENST00000453344.2
ENST00000547307.1
ENST00000547805.1
ARSA






arylsulfatase A






chr9_-_113341985 0.267 ENST00000374469.1
SVEP1
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr2_-_20850813 0.267 ENST00000402541.1
ENST00000406618.3
ENST00000304031.3
HS1BP3


HCLS1 binding protein 3


chr11_-_72414256 0.267 ENST00000427971.2
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr11_+_66624527 0.261 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr7_-_150777949 0.260 ENST00000482571.1
FASTK
Fas-activated serine/threonine kinase
chr19_-_47922373 0.259 ENST00000559524.1
ENST00000557833.1
ENST00000558555.1
ENST00000561293.1
ENST00000441740.2
MEIS3




Meis homeobox 3




chr14_-_23762777 0.259 ENST00000431326.2
HOMEZ
homeobox and leucine zipper encoding
chr19_+_55897699 0.257 ENST00000558131.1
ENST00000558752.1
ENST00000458349.2
RPL28


ribosomal protein L28


chr17_-_7307358 0.255 ENST00000535512.1
ENST00000576017.1
ENST00000302422.3
TMEM256-PLSCR3
TMEM256

TMEM256-PLSCR3 readthrough (NMD candidate)
transmembrane protein 256

chr16_-_25122735 0.254 ENST00000563176.1
RP11-449H11.1
RP11-449H11.1
chr19_-_47734448 0.251 ENST00000439096.2
BBC3
BCL2 binding component 3
chr1_+_24117627 0.248 ENST00000400061.1
LYPLA2
lysophospholipase II
chr2_+_113033164 0.248 ENST00000409871.1
ENST00000343936.4
ZC3H6

zinc finger CCCH-type containing 6

chr9_-_113342160 0.247 ENST00000401783.2
ENST00000374461.1
SVEP1

sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1

chr22_+_18893736 0.245 ENST00000331444.6
DGCR6
DiGeorge syndrome critical region gene 6
chr11_-_8832182 0.245 ENST00000527510.1
ENST00000528527.1
ENST00000528523.1
ENST00000313726.6
ST5



suppression of tumorigenicity 5



chr3_+_154797781 0.244 ENST00000382989.3
MME
membrane metallo-endopeptidase
chr1_+_32827759 0.244 ENST00000373534.3
TSSK3
testis-specific serine kinase 3
chr20_-_35374456 0.244 ENST00000373803.2
ENST00000359675.2
ENST00000540765.1
ENST00000349004.1
NDRG3



NDRG family member 3



chr14_+_21538517 0.243 ENST00000298693.3
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr20_+_34680620 0.243 ENST00000430276.1
ENST00000373950.2
ENST00000452261.1
EPB41L1


erythrocyte membrane protein band 4.1-like 1


chr8_-_128231299 0.242 ENST00000500112.1
CCAT1
colon cancer associated transcript 1 (non-protein coding)
chr8_-_144886321 0.242 ENST00000526832.1
SCRIB
scribbled planar cell polarity protein
chr11_-_44972390 0.239 ENST00000395648.3
ENST00000531928.2
TP53I11

tumor protein p53 inducible protein 11


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.3 2.2 GO:0060437 lung growth(GO:0060437)
0.2 0.7 GO:0045210 negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210)
0.2 0.7 GO:0006097 glyoxylate cycle(GO:0006097)
0.2 0.9 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.2 1.3 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.2 0.7 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.2 1.2 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.1 0.4 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.1 0.5 GO:1904106 protein localization to microvillus(GO:1904106)
0.1 0.4 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.7 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.4 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.1 0.4 GO:0086055 atrial ventricular junction remodeling(GO:0003294) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
0.1 0.5 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.9 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 1.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.9 GO:1904879 positive regulation of high voltage-gated calcium channel activity(GO:1901843) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 0.2 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 1.2 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.5 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.6 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.8 GO:0044375 regulation of peroxisome size(GO:0044375)
0.1 0.4 GO:0007566 embryo implantation(GO:0007566)
0.1 0.4 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 0.4 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.1 0.3 GO:0042631 cellular response to water deprivation(GO:0042631)
0.1 0.5 GO:2000035 regulation of stem cell division(GO:2000035)
0.1 0.2 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.1 0.2 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 0.3 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.1 0.4 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.4 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.1 3.7 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.4 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 0.3 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 1.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.5 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.2 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.1 0.4 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.1 2.1 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 0.3 GO:0042351 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.1 0.5 GO:0046541 saliva secretion(GO:0046541)
0.1 0.5 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.1 0.4 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 0.2 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 1.5 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 0.3 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.4 GO:0014028 notochord formation(GO:0014028)
0.1 0.2 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.3 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.1 0.3 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 0.3 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.1 0.3 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.2 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 1.0 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.2 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.1 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.0 0.5 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.7 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.2 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.4 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.3 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.5 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.4 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.7 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.3 GO:0060480 lung goblet cell differentiation(GO:0060480) lobar bronchus epithelium development(GO:0060481) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.1 GO:0090182 regulation of secretion of lysosomal enzymes(GO:0090182)
0.0 0.2 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.2 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.7 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.0 GO:0060300 regulation of cytokine activity(GO:0060300)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.2 GO:0050668 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) positive regulation of homocysteine metabolic process(GO:0050668)
0.0 0.1 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.3 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.2 GO:1903969 mammary gland fat development(GO:0060611) regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) regulation of response to macrophage colony-stimulating factor(GO:1903969) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.0 0.2 GO:0051958 methotrexate transport(GO:0051958)
0.0 0.9 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.3 GO:1904378 maintenance of unfolded protein(GO:0036506) protein localization to cytosolic proteasome complex(GO:1904327) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.1 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.0 0.3 GO:0060346 bone trabecula formation(GO:0060346)
0.0 0.2 GO:0071104 response to interleukin-9(GO:0071104)
0.0 0.2 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.2 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) protein O-linked glycosylation via serine(GO:0018242)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.2 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.4 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.4 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.5 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.1 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
0.0 0.2 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 1.0 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.1 GO:0072081 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081) specification of loop of Henle identity(GO:0072086)
0.0 0.2 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.1 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.1 GO:0019075 virus maturation(GO:0019075)
0.0 0.7 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.4 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 1.0 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.4 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.8 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.0 0.4 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.3 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.6 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.0 0.7 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.1 GO:0007506 gonadal mesoderm development(GO:0007506)
0.0 0.7 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.1 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.1 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.1 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 0.1 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.1 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.3 GO:0044854 plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857)
0.0 0.2 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.6 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.8 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.8 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.0 0.2 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.2 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.1 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.4 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.2 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.3 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.1 GO:0002432 granuloma formation(GO:0002432)
0.0 0.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.0 GO:1990697 protein depalmitoleylation(GO:1990697)
0.0 0.0 GO:0048867 ganglion mother cell fate determination(GO:0007402) stem cell fate determination(GO:0048867)
0.0 0.2 GO:2000194 regulation of female gonad development(GO:2000194)
0.0 0.0 GO:0007412 axon target recognition(GO:0007412)
0.0 0.2 GO:0018958 phenol-containing compound metabolic process(GO:0018958)
0.0 0.1 GO:0006601 creatine biosynthetic process(GO:0006601)
0.0 0.1 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.1 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
0.0 0.1 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.0 0.1 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.1 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.1 GO:2000858 mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of mineralocorticoid secretion(GO:2000855) positive regulation of mineralocorticoid secretion(GO:2000857) regulation of aldosterone secretion(GO:2000858) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.0 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.1 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) regulation of skeletal muscle tissue growth(GO:0048631) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.0 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.0 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.1 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.1 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653) regulation of hemoglobin biosynthetic process(GO:0046984) positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.1 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.3 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 1.2 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.4 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.8 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.1 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.0 0.1 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.0 0.7 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.0 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.1 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0 0.2 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.1 GO:0002118 aggressive behavior(GO:0002118) amygdala development(GO:0021764)
0.0 0.1 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.1 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 0.5 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.1 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.1 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.1 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.1 GO:0043091 response to selenium ion(GO:0010269) L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.0 0.1 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.1 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.0 GO:0002877 acute inflammatory response to non-antigenic stimulus(GO:0002525) regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.2 GO:0015866 ADP transport(GO:0015866)
0.0 0.0 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 0.2 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.0 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.5 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.4 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.1 0.7 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 0.7 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 0.4 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.4 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 0.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.2 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.9 GO:0070652 HAUS complex(GO:0070652)
0.1 0.4 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 0.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.9 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.3 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.5 GO:0071953 elastic fiber(GO:0071953)
0.1 0.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.5 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.7 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.3 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 1.0 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 1.0 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.3 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.2 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.3 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.3 GO:0031906 late endosome lumen(GO:0031906)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 1.6 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.2 GO:0070531 BRCA1-A complex(GO:0070531) BRISC complex(GO:0070552)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 1.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 1.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 1.0 GO:1904724 tertiary granule lumen(GO:1904724)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.2 0.9 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.2 0.7 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.2 0.6 GO:0045485 omega-6 fatty acid desaturase activity(GO:0045485)
0.2 0.7 GO:0004522 ribonuclease A activity(GO:0004522)
0.2 0.5 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 1.8 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 1.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.4 GO:0086079 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
0.1 1.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.9 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.4 GO:0005199 structural constituent of cell wall(GO:0005199)
0.1 0.5 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.4 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.1 0.4 GO:0061714 folic acid receptor activity(GO:0061714)
0.1 0.7 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.3 GO:0050577 GDP-4-dehydro-D-rhamnose reductase activity(GO:0042356) GDP-L-fucose synthase activity(GO:0050577)
0.1 0.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 1.0 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.9 GO:0097016 L27 domain binding(GO:0097016)
0.1 1.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.2 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 1.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.2 GO:0008430 selenium binding(GO:0008430)
0.1 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.4 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.1 0.7 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.4 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 0.2 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 1.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.2 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.0 0.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.4 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 1.0 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.4 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 4.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.3 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.2 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.1 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.0 0.4 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.5 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.0 0.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.2 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0015350 methotrexate transporter activity(GO:0015350)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.6 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.5 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.4 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.0 0.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.1 GO:0015067 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.6 GO:0070628 proteasome binding(GO:0070628)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.0 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.0 0.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.0 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.0 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 1.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.0 GO:0036122 BMP binding(GO:0036122)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.0 GO:0042007 interleukin-18 binding(GO:0042007)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.0 GO:0005055 laminin receptor activity(GO:0005055)
0.0 0.2 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.0 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.0 3.9 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 1.5 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.4 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.8 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 1.4 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 3.8 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.5 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.1 1.5 REACTOME_ACTIVATED_POINT_MUTANTS_OF_FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.7 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.7 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.6 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.6 REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.9 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 2.0 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.7 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.9 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.7 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.5 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.8 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.5 REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.7 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.6 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION Genes involved in Binding and entry of HIV virion
0.0 0.5 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.1 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.3 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.2 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.4 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME_SCFSKP2_MEDIATED_DEGRADATION_OF_P27_P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.6 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 1.3 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.5 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.6 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)