Motif ID: RUNX3_BCL11A

Z-value: 0.402

Transcription factors associated with RUNX3_BCL11A:

Gene SymbolEntrez IDGene Name
BCL11A ENSG00000119866.16 BCL11A
RUNX3 ENSG00000020633.14 RUNX3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
RUNX3hg19_v2_chr1_-_25291475_252915110.809.7e-03Click!
BCL11Ahg19_v2_chr2_-_60780702_60780742-0.491.8e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of RUNX3_BCL11A

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_35856951 2.456 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R



interleukin 7 receptor



chr6_+_45296391 0.921 ENST00000371436.6
ENST00000576263.1
RUNX2

runt-related transcription factor 2

chr9_-_32526299 0.783 ENST00000379882.1
ENST00000379883.2
DDX58

DEAD (Asp-Glu-Ala-Asp) box polypeptide 58

chr5_-_35938674 0.606 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
CAPSL



calcyphosine-like



chr15_+_67390920 0.513 ENST00000559092.1
ENST00000560175.1
SMAD3

SMAD family member 3

chr10_+_17272608 0.442 ENST00000421459.2
VIM
vimentin
chr19_+_36203830 0.438 ENST00000262630.3
ZBTB32
zinc finger and BTB domain containing 32
chr1_+_66796401 0.420 ENST00000528771.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr17_+_38673270 0.368 ENST00000578280.1
RP5-1028K7.2
RP5-1028K7.2
chr5_-_138861926 0.355 ENST00000510817.1
TMEM173
transmembrane protein 173
chrX_+_37639302 0.353 ENST00000545017.1
ENST00000536160.1
CYBB

cytochrome b-245, beta polypeptide

chr1_-_98511756 0.339 ENST00000602984.1
ENST00000602852.1
MIR137HG

MIR137 host gene (non-protein coding)

chr1_-_94147385 0.321 ENST00000260502.6
BCAR3
breast cancer anti-estrogen resistance 3
chr21_-_36421535 0.311 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
RUNX1


runt-related transcription factor 1


chrX_-_19688475 0.309 ENST00000541422.1
SH3KBP1
SH3-domain kinase binding protein 1
chr10_+_17270214 0.293 ENST00000544301.1
VIM
vimentin
chr6_+_86159821 0.290 ENST00000369651.3
NT5E
5'-nucleotidase, ecto (CD73)
chr6_+_45296048 0.285 ENST00000465038.2
ENST00000352853.5
ENST00000541979.1
ENST00000371438.1
RUNX2



runt-related transcription factor 2



chr12_-_15114492 0.285 ENST00000541546.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chrX_+_37639264 0.274 ENST00000378588.4
CYBB
cytochrome b-245, beta polypeptide
chr1_-_179112173 0.270 ENST00000408940.3
ENST00000504405.1
ABL2

c-abl oncogene 2, non-receptor tyrosine kinase

chr1_-_179112189 0.270 ENST00000512653.1
ENST00000344730.3
ABL2

c-abl oncogene 2, non-receptor tyrosine kinase

chr7_+_18535346 0.266 ENST00000405010.3
ENST00000406451.4
ENST00000428307.2
HDAC9


histone deacetylase 9


chr15_-_60695071 0.266 ENST00000557904.1
ANXA2
annexin A2
chr11_+_35198118 0.252 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
CD44



CD44 molecule (Indian blood group)



chr5_-_94417314 0.249 ENST00000505208.1
MCTP1
multiple C2 domains, transmembrane 1
chr5_-_94417562 0.244 ENST00000505465.1
MCTP1
multiple C2 domains, transmembrane 1
chr5_-_94417186 0.240 ENST00000312216.8
ENST00000512425.1
MCTP1

multiple C2 domains, transmembrane 1

chr12_-_15114191 0.236 ENST00000541380.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr11_-_128457446 0.233 ENST00000392668.4
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr21_-_36421626 0.232 ENST00000300305.3
RUNX1
runt-related transcription factor 1
chr9_-_34048873 0.217 ENST00000449054.1
ENST00000379239.4
ENST00000539807.1
ENST00000379238.1
ENST00000418786.2
ENST00000360802.1
ENST00000412543.1
UBAP2






ubiquitin associated protein 2






chr11_+_35198243 0.212 ENST00000528455.1
CD44
CD44 molecule (Indian blood group)
chr14_+_51955831 0.208 ENST00000356218.4
FRMD6
FERM domain containing 6
chr9_+_75766763 0.204 ENST00000456643.1
ENST00000415424.1
ANXA1

annexin A1

chr17_-_39661849 0.202 ENST00000246635.3
ENST00000336861.3
ENST00000587544.1
ENST00000587435.1
KRT13



keratin 13



chr9_+_75766652 0.200 ENST00000257497.6
ANXA1
annexin A1
chrX_-_54209640 0.198 ENST00000375180.2
ENST00000328235.4
ENST00000477084.1
FAM120C


family with sequence similarity 120C


chr3_+_51575596 0.196 ENST00000409535.2
RAD54L2
RAD54-like 2 (S. cerevisiae)
chr4_-_84035868 0.196 ENST00000426923.2
ENST00000509973.1
PLAC8

placenta-specific 8

chr10_+_101419187 0.193 ENST00000370489.4
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chr4_-_84035905 0.187 ENST00000311507.4
PLAC8
placenta-specific 8
chr17_+_38599693 0.185 ENST00000542955.1
ENST00000269593.4
IGFBP4

insulin-like growth factor binding protein 4

chr1_-_157014865 0.181 ENST00000361409.2
ARHGEF11
Rho guanine nucleotide exchange factor (GEF) 11
chr11_-_118436707 0.173 ENST00000264020.2
ENST00000264021.3
IFT46

intraflagellar transport 46 homolog (Chlamydomonas)

chr1_-_217250231 0.173 ENST00000493748.1
ENST00000463665.1
ESRRG

estrogen-related receptor gamma

chr6_+_12290586 0.172 ENST00000379375.5
EDN1
endothelin 1
chr5_-_94417339 0.170 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1


multiple C2 domains, transmembrane 1


chr22_-_30642728 0.169 ENST00000403987.3
LIF
leukemia inhibitory factor
chr17_+_76037081 0.169 ENST00000588549.1
TNRC6C
trinucleotide repeat containing 6C
chr16_-_69418649 0.166 ENST00000566257.1
TERF2
telomeric repeat binding factor 2
chr1_-_25291475 0.164 ENST00000338888.3
ENST00000399916.1
RUNX3

runt-related transcription factor 3

chr5_+_176074455 0.163 ENST00000298564.10
ENST00000508164.1
ENST00000504168.1
ENST00000503045.1
ENST00000515708.1
ENST00000507471.1
TSPAN17





tetraspanin 17





chr6_+_30029008 0.156 ENST00000332435.5
ENST00000376782.2
ENST00000359374.4
ENST00000376785.2
ZNRD1



zinc ribbon domain containing 1



chr2_-_207078154 0.156 ENST00000447845.1
GPR1
G protein-coupled receptor 1
chr15_+_73976545 0.155 ENST00000318443.5
ENST00000537340.2
ENST00000318424.5
CD276


CD276 molecule


chr5_+_176074388 0.152 ENST00000310032.8
ENST00000405525.2
TSPAN17

tetraspanin 17

chrX_-_49121165 0.151 ENST00000376207.4
ENST00000376199.2
FOXP3

forkhead box P3

chr2_-_207078086 0.148 ENST00000442134.1
GPR1
G protein-coupled receptor 1
chr3_-_134093738 0.147 ENST00000506107.1
AMOTL2
angiomotin like 2
chr11_+_86502085 0.147 ENST00000527521.1
PRSS23
protease, serine, 23
chr6_-_42418999 0.146 ENST00000340840.2
ENST00000354325.2
TRERF1

transcriptional regulating factor 1

chr10_+_25463951 0.145 ENST00000376351.3
GPR158
G protein-coupled receptor 158
chr22_-_30642782 0.143 ENST00000249075.3
LIF
leukemia inhibitory factor
chrX_+_68048803 0.140 ENST00000204961.4
EFNB1
ephrin-B1
chr15_+_73976715 0.136 ENST00000558689.1
ENST00000560786.2
ENST00000561213.1
ENST00000563584.1
ENST00000561416.1
CD276




CD276 molecule




chr16_+_84801852 0.135 ENST00000569925.1
ENST00000567526.1
USP10

ubiquitin specific peptidase 10

chr20_+_36405665 0.134 ENST00000373469.1
CTNNBL1
catenin, beta like 1
chr15_+_67418047 0.134 ENST00000540846.2
SMAD3
SMAD family member 3
chr11_-_67141090 0.133 ENST00000312438.7
CLCF1
cardiotrophin-like cytokine factor 1
chr19_+_13135386 0.132 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
NFIX


nuclear factor I/X (CCAAT-binding transcription factor)


chr11_-_66103867 0.130 ENST00000424433.2
RIN1
Ras and Rab interactor 1
chr16_-_69418553 0.129 ENST00000569542.2
TERF2
telomeric repeat binding factor 2
chr4_+_78783674 0.127 ENST00000315567.8
MRPL1
mitochondrial ribosomal protein L1
chr1_-_207095324 0.127 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3


Fas apoptotic inhibitory molecule 3


chr11_-_118436606 0.113 ENST00000530872.1
IFT46
intraflagellar transport 46 homolog (Chlamydomonas)
chr20_-_45035223 0.112 ENST00000450812.1
ENST00000290246.6
ENST00000439931.2
ENST00000396391.1
ELMO2



engulfment and cell motility 2



chr16_+_67312049 0.112 ENST00000565899.1
PLEKHG4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr12_-_48276710 0.111 ENST00000550314.1
VDR
vitamin D (1,25- dihydroxyvitamin D3) receptor
chr8_-_19540086 0.110 ENST00000332246.6
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr8_-_19540266 0.108 ENST00000311540.4
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr11_-_67141640 0.107 ENST00000533438.1
CLCF1
cardiotrophin-like cytokine factor 1
chr2_+_97202480 0.107 ENST00000357485.3
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr11_-_58345569 0.106 ENST00000528954.1
ENST00000528489.1
LPXN

leupaxin

chr7_+_18535321 0.103 ENST00000413380.1
ENST00000430454.1
HDAC9

histone deacetylase 9

chr17_-_73781567 0.103 ENST00000586607.1
H3F3B
H3 histone, family 3B (H3.3B)
chr17_-_47287928 0.102 ENST00000507680.1
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr5_+_148206156 0.099 ENST00000305988.4
ADRB2
adrenoceptor beta 2, surface
chr12_-_120662499 0.097 ENST00000552550.1
PXN
paxillin
chr3_-_33686925 0.097 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2


cytoplasmic linker associated protein 2


chr12_+_93772402 0.096 ENST00000546925.1
NUDT4
nudix (nucleoside diphosphate linked moiety X)-type motif 4
chr2_+_97203082 0.096 ENST00000454558.2
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr11_-_66104237 0.095 ENST00000530056.1
RIN1
Ras and Rab interactor 1
chr4_-_152147579 0.095 ENST00000304527.4
ENST00000455740.1
ENST00000424281.1
ENST00000409598.4
SH3D19



SH3 domain containing 19



chr3_-_189840223 0.094 ENST00000427335.2
LEPREL1
leprecan-like 1
chr12_+_93772326 0.093 ENST00000550056.1
ENST00000549992.1
ENST00000548662.1
ENST00000547014.1
NUDT4



nudix (nucleoside diphosphate linked moiety X)-type motif 4



chr21_+_30673091 0.092 ENST00000447177.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr6_+_5030205 0.091 ENST00000606761.1
ENST00000607327.1
ENST00000606767.1
RP11-428J1.5


RP11-428J1.5


chr3_+_40518599 0.090 ENST00000314686.5
ENST00000447116.2
ENST00000429348.2
ENST00000456778.1
ZNF619



zinc finger protein 619



chr6_+_31514622 0.090 ENST00000376146.4
NFKBIL1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr3_-_71179988 0.089 ENST00000491238.1
FOXP1
forkhead box P1
chr6_+_42847649 0.088 ENST00000424341.2
ENST00000602561.1
RPL7L1

ribosomal protein L7-like 1

chr7_+_45067265 0.087 ENST00000474617.1
CCM2
cerebral cavernous malformation 2
chr2_+_173955327 0.086 ENST00000422149.1
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr10_-_29811456 0.085 ENST00000535393.1
SVIL
supervillin
chr3_-_71179699 0.085 ENST00000497355.1
FOXP1
forkhead box P1
chr11_-_66103932 0.084 ENST00000311320.4
RIN1
Ras and Rab interactor 1
chr20_-_45035198 0.083 ENST00000372176.1
ELMO2
engulfment and cell motility 2
chr3_+_156799587 0.081 ENST00000469196.1
RP11-6F2.5
RP11-6F2.5
chr1_+_66999799 0.077 ENST00000371035.3
ENST00000371036.3
ENST00000371037.4
SGIP1


SH3-domain GRB2-like (endophilin) interacting protein 1


chr5_+_145316120 0.077 ENST00000359120.4
SH3RF2
SH3 domain containing ring finger 2
chr1_-_113161730 0.076 ENST00000544629.1
ENST00000543570.1
ENST00000360743.4
ENST00000490067.1
ENST00000343210.7
ENST00000369666.1
ST7L





suppression of tumorigenicity 7 like





chr16_-_89785777 0.076 ENST00000561976.1
VPS9D1
VPS9 domain containing 1
chr11_-_19262486 0.076 ENST00000250024.4
E2F8
E2F transcription factor 8
chr16_-_12009833 0.076 ENST00000420576.2
GSPT1
G1 to S phase transition 1
chrX_-_49041242 0.075 ENST00000453382.1
ENST00000540849.1
ENST00000536904.1
ENST00000432913.1
PRICKLE3



prickle homolog 3 (Drosophila)



chr2_+_112813134 0.075 ENST00000452614.1
TMEM87B
transmembrane protein 87B
chr16_+_58033450 0.074 ENST00000561743.1
USB1
U6 snRNA biogenesis 1
chr1_+_179050512 0.073 ENST00000367627.3
TOR3A
torsin family 3, member A
chr17_-_41623009 0.072 ENST00000393664.2
ETV4
ets variant 4
chr2_+_173292059 0.072 ENST00000412899.1
ENST00000409532.1
ITGA6

integrin, alpha 6

chr18_+_3448455 0.071 ENST00000549780.1
TGIF1
TGFB-induced factor homeobox 1
chr3_+_141105235 0.070 ENST00000503809.1
ZBTB38
zinc finger and BTB domain containing 38
chr16_+_2802623 0.070 ENST00000576924.1
ENST00000575009.1
ENST00000576415.1
ENST00000571378.1
SRRM2



serine/arginine repetitive matrix 2



chr1_+_117544366 0.070 ENST00000256652.4
ENST00000369470.1
CD101

CD101 molecule

chr17_-_41623075 0.070 ENST00000545089.1
ETV4
ets variant 4
chr2_+_173292390 0.070 ENST00000442250.1
ENST00000458358.1
ENST00000409080.1
ITGA6


integrin, alpha 6


chr20_+_19870167 0.069 ENST00000440354.2
RIN2
Ras and Rab interactor 2
chr1_+_155290677 0.069 ENST00000368354.3
ENST00000368352.5
RUSC1

RUN and SH3 domain containing 1

chr1_+_151171012 0.069 ENST00000349792.5
ENST00000409426.1
ENST00000441902.2
ENST00000368890.4
ENST00000424999.1
ENST00000368888.4
PIP5K1A





phosphatidylinositol-4-phosphate 5-kinase, type I, alpha





chr4_+_2800722 0.069 ENST00000508385.1
SH3BP2
SH3-domain binding protein 2
chr22_+_42665742 0.069 ENST00000332965.3
ENST00000415205.1
ENST00000446578.1
Z83851.3


Z83851.3


chr1_-_24469602 0.069 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chr16_-_12009735 0.068 ENST00000439887.2
ENST00000434724.2
GSPT1

G1 to S phase transition 1

chr1_-_95391315 0.067 ENST00000545882.1
ENST00000415017.1
CNN3

calponin 3, acidic

chr2_+_217277137 0.067 ENST00000430374.1
ENST00000357276.4
ENST00000444508.1
SMARCAL1


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1


chr1_-_175161890 0.067 ENST00000545251.2
ENST00000423313.1
KIAA0040

KIAA0040

chr3_-_33686743 0.066 ENST00000333778.6
ENST00000539981.1
CLASP2

cytoplasmic linker associated protein 2

chr8_-_112248400 0.066 ENST00000519506.1
ENST00000522778.1
RP11-946L20.4

RP11-946L20.4

chr1_-_173174681 0.065 ENST00000367718.1
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr6_-_152623231 0.065 ENST00000540663.1
ENST00000537033.1
SYNE1

spectrin repeat containing, nuclear envelope 1

chr2_+_173292301 0.064 ENST00000264106.6
ENST00000375221.2
ENST00000343713.4
ITGA6


integrin, alpha 6


chr2_+_217277466 0.064 ENST00000358207.5
ENST00000434435.1
SMARCAL1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1

chr2_+_173292280 0.063 ENST00000264107.7
ITGA6
integrin, alpha 6
chr1_+_113161778 0.062 ENST00000263168.3
CAPZA1
capping protein (actin filament) muscle Z-line, alpha 1
chr1_+_179051160 0.060 ENST00000367625.4
ENST00000352445.6
TOR3A

torsin family 3, member A

chr8_-_99954788 0.060 ENST00000523601.1
STK3
serine/threonine kinase 3
chr6_+_30295036 0.059 ENST00000376659.5
ENST00000428555.1
TRIM39

tripartite motif containing 39

chr20_+_43991668 0.059 ENST00000243918.5
ENST00000426004.1
SYS1

SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)

chr1_-_113162040 0.059 ENST00000358039.4
ENST00000369668.2
ST7L

suppression of tumorigenicity 7 like

chr1_-_114414316 0.059 ENST00000528414.1
ENST00000538253.1
ENST00000460620.1
ENST00000420377.2
ENST00000525799.1
ENST00000359785.5
PTPN22





protein tyrosine phosphatase, non-receptor type 22 (lymphoid)





chr14_-_23564320 0.058 ENST00000605057.1
ACIN1
apoptotic chromatin condensation inducer 1
chr8_-_22926623 0.058 ENST00000276431.4
TNFRSF10B
tumor necrosis factor receptor superfamily, member 10b
chrX_+_47441712 0.057 ENST00000218388.4
ENST00000377018.2
ENST00000456754.2
ENST00000377017.1
ENST00000441738.1
TIMP1




TIMP metallopeptidase inhibitor 1




chr1_+_44889697 0.057 ENST00000443020.2
RNF220
ring finger protein 220
chr9_+_131799213 0.056 ENST00000358369.4
ENST00000406926.2
ENST00000277475.5
ENST00000450073.1
FAM73B



family with sequence similarity 73, member B



chr8_-_11325047 0.056 ENST00000531804.1
FAM167A
family with sequence similarity 167, member A
chr6_+_15401075 0.056 ENST00000541660.1
JARID2
jumonji, AT rich interactive domain 2
chr1_-_173176452 0.056 ENST00000281834.3
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr5_-_137878887 0.055 ENST00000507939.1
ENST00000572514.1
ENST00000499810.2
ENST00000360541.5
ETF1



eukaryotic translation termination factor 1



chr17_-_73840614 0.055 ENST00000586108.1
UNC13D
unc-13 homolog D (C. elegans)
chr3_+_49977440 0.055 ENST00000442092.1
ENST00000266022.4
ENST00000443081.1
RBM6


RNA binding motif protein 6


chr17_+_46185111 0.055 ENST00000582104.1
ENST00000584335.1
SNX11

sorting nexin 11

chr19_+_13135790 0.055 ENST00000358552.3
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr1_-_86043921 0.054 ENST00000535924.2
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr2_-_71221942 0.054 ENST00000272438.4
TEX261
testis expressed 261
chr7_+_18330035 0.053 ENST00000413509.2
HDAC9
histone deacetylase 9
chr6_+_30294612 0.053 ENST00000440271.1
ENST00000396551.3
ENST00000376656.4
ENST00000540416.1
ENST00000428728.1
ENST00000396548.1
ENST00000428404.1
TRIM39






tripartite motif containing 39






chr19_-_42636617 0.053 ENST00000529067.1
ENST00000529952.1
ENST00000533720.1
ENST00000389341.5
ENST00000342301.4
POU2F2




POU class 2 homeobox 2




chr1_+_156308403 0.053 ENST00000481479.1
ENST00000368252.1
ENST00000466306.1
ENST00000368251.1
TSACC



TSSK6 activating co-chaperone



chr19_+_36208877 0.051 ENST00000420124.1
ENST00000222270.7
ENST00000341701.1
KMT2B


Histone-lysine N-methyltransferase 2B


chr12_+_75874984 0.051 ENST00000550491.1
GLIPR1
GLI pathogenesis-related 1
chr6_-_143771799 0.051 ENST00000237283.8
ADAT2
adenosine deaminase, tRNA-specific 2
chr10_+_82219058 0.051 ENST00000372156.1
TSPAN14
tetraspanin 14
chr12_-_49245916 0.051 ENST00000552512.1
ENST00000551468.1
DDX23

DEAD (Asp-Glu-Ala-Asp) box polypeptide 23

chr5_+_147648393 0.050 ENST00000511106.1
ENST00000398450.4
SPINK13

serine peptidase inhibitor, Kazal type 13 (putative)

chr19_+_13135731 0.050 ENST00000587260.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr17_+_19281787 0.049 ENST00000482850.1
MAPK7
mitogen-activated protein kinase 7
chr2_-_38466726 0.048 ENST00000450854.1
AC009229.5
AC009229.5
chr16_-_58033762 0.047 ENST00000299237.2
ZNF319
zinc finger protein 319
chr14_-_105767598 0.047 ENST00000548421.1
BRF1
BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
chr1_-_168464875 0.047 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chrX_-_47509994 0.047 ENST00000343894.4
ELK1
ELK1, member of ETS oncogene family
chr22_+_21996549 0.046 ENST00000248958.4
SDF2L1
stromal cell-derived factor 2-like 1
chr3_-_100558953 0.046 ENST00000533795.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr13_-_99910620 0.046 ENST00000416594.1
GPR18
G protein-coupled receptor 18
chr2_+_53994927 0.045 ENST00000295304.4
CHAC2
ChaC, cation transport regulator homolog 2 (E. coli)
chr12_-_14956396 0.045 ENST00000535328.1
ENST00000261167.2
WBP11

WW domain binding protein 11

chr16_+_12995614 0.045 ENST00000423335.2
SHISA9
shisa family member 9
chr12_-_49245936 0.045 ENST00000308025.3
DDX23
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
chr15_+_68582544 0.045 ENST00000566008.1
FEM1B
fem-1 homolog b (C. elegans)
chr2_+_73461364 0.045 ENST00000540468.1
ENST00000539919.1
ENST00000258091.5
CCT7


chaperonin containing TCP1, subunit 7 (eta)


chr2_-_111291587 0.044 ENST00000437167.1
RGPD6
RANBP2-like and GRIP domain containing 6
chr17_+_45728427 0.044 ENST00000540627.1
KPNB1
karyopherin (importin) beta 1
chr9_-_35103105 0.044 ENST00000452248.2
ENST00000356493.5
STOML2

stomatin (EPB72)-like 2

chr6_+_31515337 0.044 ENST00000376148.4
ENST00000376145.4
NFKBIL1

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1

chr2_+_73461410 0.044 ENST00000399032.2
ENST00000398422.2
ENST00000537131.1
ENST00000538797.1
CCT7



chaperonin containing TCP1, subunit 7 (eta)



chr1_+_168545711 0.043 ENST00000367818.3
XCL1
chemokine (C motif) ligand 1
chr17_-_42188598 0.043 ENST00000591714.1
HDAC5
histone deacetylase 5
chr3_+_189349162 0.043 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
TP63





tumor protein p63






Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.2 2.5 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.2 0.2 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.1 0.4 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839) positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.6 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 1.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.6 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.5 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.3 GO:1903517 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.1 0.3 GO:0052214 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.1 0.3 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.1 0.2 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.5 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.7 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.1 0.5 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.4 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.2 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.4 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.2 GO:0030578 PML body organization(GO:0030578)
0.0 0.2 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0070376 regulation of ERK5 cascade(GO:0070376) negative regulation of ERK5 cascade(GO:0070377)
0.0 0.1 GO:1903519 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.2 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.0 0.1 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0002432 granuloma formation(GO:0002432)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499) female genitalia morphogenesis(GO:0048807)
0.0 0.1 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.4 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0 0.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.3 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.1 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.1 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.0 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.0 0.0 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) positive regulation of thymocyte migration(GO:2000412) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.0 0.1 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.0 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.0 0.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.0 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.0 0.0 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.0 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.0 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.1 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.0 GO:0097195 pilomotor reflex(GO:0097195)
0.0 0.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.0 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.1 0.2 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 0.6 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.5 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.3 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.0 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.0 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.1 0.7 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.3 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.6 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.7 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.2 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.5 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.3 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.3 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.1 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.0 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.0 0.0 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.4 GO:0043015 gamma-tubulin binding(GO:0043015)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.2 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.8 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.4 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 1.2 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.8 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.6 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation