Motif ID: RREB1

Z-value: 0.552


Transcription factors associated with RREB1:

Gene SymbolEntrez IDGene Name
RREB1 ENSG00000124782.15 RREB1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
RREB1hg19_v2_chr6_+_7107830_71079930.627.7e-02Click!


Activity profile for motif RREB1.

activity profile for motif RREB1


Sorted Z-values histogram for motif RREB1

Sorted Z-values for motif RREB1



Network of associatons between targets according to the STRING database.



First level regulatory network of RREB1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_123747979 0.772 ENST00000608478.1
FGF2
fibroblast growth factor 2 (basic)
chr4_+_123747834 0.707 ENST00000264498.3
FGF2
fibroblast growth factor 2 (basic)
chr17_-_39728303 0.672 ENST00000588431.1
ENST00000246662.4
KRT9

keratin 9

chr10_+_115438920 0.585 ENST00000429617.1
ENST00000369331.4
CASP7

caspase 7, apoptosis-related cysteine peptidase

chr19_+_55999916 0.560 ENST00000587166.1
ENST00000389623.6
SSC5D

scavenger receptor cysteine rich domain containing (5 domains)

chr1_-_153538292 0.499 ENST00000497140.1
ENST00000368708.3
S100A2

S100 calcium binding protein A2

chr12_-_53297432 0.490 ENST00000546900.1
KRT8
keratin 8
chr10_-_71930222 0.466 ENST00000458634.2
ENST00000373239.2
ENST00000373242.2
ENST00000373241.4
SAR1A



SAR1 homolog A (S. cerevisiae)



chr8_+_38261880 0.455 ENST00000527175.1
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chr11_+_7506837 0.423 ENST00000528758.1
OLFML1
olfactomedin-like 1
chr11_+_7506713 0.400 ENST00000329293.3
ENST00000534244.1
OLFML1

olfactomedin-like 1

chr11_+_7506584 0.373 ENST00000530135.1
OLFML1
olfactomedin-like 1
chr11_-_57089774 0.369 ENST00000527207.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr20_-_36793663 0.341 ENST00000536701.1
ENST00000536724.1
TGM2

transglutaminase 2

chr11_+_86511569 0.324 ENST00000441050.1
PRSS23
protease, serine, 23
chr1_-_113392399 0.317 ENST00000449572.2
ENST00000433505.1
RP11-426L16.8

RP11-426L16.8

chr11_-_57089671 0.304 ENST00000532437.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr16_+_27325202 0.299 ENST00000395762.2
ENST00000562142.1
ENST00000561742.1
ENST00000543915.2
ENST00000449195.1
ENST00000380922.3
ENST00000563002.1
IL4R






interleukin 4 receptor






chr8_+_94929969 0.298 ENST00000517764.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr13_-_74708372 0.297 ENST00000377666.4
KLF12
Kruppel-like factor 12
chr20_+_55967129 0.297 ENST00000371219.2
RBM38
RNA binding motif protein 38
chr12_+_54384370 0.288 ENST00000504315.1
HOXC6
homeobox C6
chr6_-_31681839 0.287 ENST00000461287.1
ENST00000409239.1
XXbac-BPG32J3.20
LY6G6E
Uncharacterized protein
lymphocyte antigen 6 complex, locus G6E (pseudogene)
chr10_+_17271266 0.285 ENST00000224237.5
VIM
vimentin
chr2_+_28618532 0.272 ENST00000545753.1
FOSL2
FOS-like antigen 2
chr12_+_54378849 0.271 ENST00000515593.1
HOXC10
homeobox C10
chr7_-_92465868 0.270 ENST00000424848.2
CDK6
cyclin-dependent kinase 6
chrX_+_151903207 0.270 ENST00000370287.3
CSAG1
chondrosarcoma associated gene 1
chr5_-_180230830 0.268 ENST00000427865.2
ENST00000514283.1
MGAT1

mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase

chr11_-_118436606 0.262 ENST00000530872.1
IFT46
intraflagellar transport 46 homolog (Chlamydomonas)
chr11_-_118789613 0.244 ENST00000532899.1
BCL9L
B-cell CLL/lymphoma 9-like
chr16_-_75301886 0.236 ENST00000393422.2
BCAR1
breast cancer anti-estrogen resistance 1
chrX_-_151922340 0.234 ENST00000370284.1
ENST00000543232.1
ENST00000393876.1
ENST00000393872.3
MAGEA2



melanoma antigen family A, 2



chrX_+_151903253 0.231 ENST00000452779.2
ENST00000370291.2
CSAG1

chondrosarcoma associated gene 1

chr16_+_21169976 0.227 ENST00000572258.1
ENST00000261388.3
ENST00000451578.2
ENST00000572599.1
ENST00000577162.1
TMEM159




transmembrane protein 159




chr16_+_69599861 0.221 ENST00000354436.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr18_+_55102917 0.218 ENST00000491143.2
ONECUT2
one cut homeobox 2
chr3_-_42003479 0.215 ENST00000420927.1
ULK4
unc-51 like kinase 4
chr2_-_128432639 0.215 ENST00000545738.2
ENST00000355119.4
ENST00000409808.2
LIMS2


LIM and senescent cell antigen-like domains 2


chr12_-_48214345 0.212 ENST00000433685.1
ENST00000447463.1
ENST00000427332.2
HDAC7


histone deacetylase 7


chr19_-_42759300 0.209 ENST00000222329.4
ERF
Ets2 repressor factor
chr19_-_12405689 0.208 ENST00000355684.5
ZNF44
zinc finger protein 44
chr22_+_41487711 0.206 ENST00000263253.7
EP300
E1A binding protein p300
chr19_-_12405606 0.205 ENST00000356109.5
ZNF44
zinc finger protein 44
chr16_-_11617444 0.204 ENST00000598234.1
CTD-3088G3.8
Protein LOC388210
chr1_+_154975110 0.200 ENST00000535420.1
ENST00000368426.3
ZBTB7B

zinc finger and BTB domain containing 7B

chr11_-_74109422 0.192 ENST00000298198.4
PGM2L1
phosphoglucomutase 2-like 1
chr18_+_72166564 0.191 ENST00000583216.1
ENST00000581912.1
ENST00000582589.1
CNDP2


CNDP dipeptidase 2 (metallopeptidase M20 family)


chr15_+_75498739 0.189 ENST00000565074.1
C15orf39
chromosome 15 open reading frame 39
chr14_-_71067360 0.189 ENST00000554963.1
ENST00000430055.2
ENST00000440435.2
ENST00000256379.5
MED6



mediator complex subunit 6



chr19_+_55999771 0.188 ENST00000594321.1
SSC5D
scavenger receptor cysteine rich domain containing (5 domains)
chr19_-_30205963 0.184 ENST00000392278.2
C19orf12
chromosome 19 open reading frame 12
chr7_-_752074 0.183 ENST00000360274.4
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr1_+_157963063 0.183 ENST00000360089.4
ENST00000368173.3
ENST00000392272.2
KIRREL


kin of IRRE like (Drosophila)


chr17_-_73840774 0.178 ENST00000207549.4
UNC13D
unc-13 homolog D (C. elegans)
chr19_+_3366547 0.176 ENST00000341919.3
ENST00000590282.1
ENST00000443272.2
NFIC


nuclear factor I/C (CCAAT-binding transcription factor)


chr3_-_39196049 0.176 ENST00000514182.1
CSRNP1
cysteine-serine-rich nuclear protein 1
chr17_+_7482785 0.174 ENST00000250092.6
ENST00000380498.6
ENST00000584502.1
CD68


CD68 molecule


chr19_+_41305085 0.173 ENST00000303961.4
EGLN2
egl-9 family hypoxia-inducible factor 2
chr17_-_73840415 0.173 ENST00000592386.1
ENST00000412096.2
ENST00000586147.1
UNC13D


unc-13 homolog D (C. elegans)


chr19_-_30206128 0.170 ENST00000392276.1
ENST00000592153.1
ENST00000323670.9
C19orf12


chromosome 19 open reading frame 12


chr17_-_73840614 0.169 ENST00000586108.1
UNC13D
unc-13 homolog D (C. elegans)
chr3_+_133524459 0.169 ENST00000484684.1
SRPRB
signal recognition particle receptor, B subunit
chrX_-_148571884 0.166 ENST00000537071.1
IDS
iduronate 2-sulfatase
chr9_+_131174024 0.163 ENST00000420034.1
ENST00000372842.1
CERCAM

cerebral endothelial cell adhesion molecule

chr7_+_76101379 0.161 ENST00000429179.1
DTX2
deltex homolog 2 (Drosophila)
chr3_-_71632894 0.159 ENST00000493089.1
FOXP1
forkhead box P1
chr18_+_72167096 0.155 ENST00000324301.8
CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr16_-_3285144 0.155 ENST00000431561.3
ENST00000396870.4
ZNF200

zinc finger protein 200

chr19_+_41305406 0.154 ENST00000406058.2
ENST00000593726.1
EGLN2

egl-9 family hypoxia-inducible factor 2

chrX_+_151883090 0.152 ENST00000370293.2
ENST00000423993.1
ENST00000447530.1
ENST00000458057.1
ENST00000331220.2
ENST00000422085.1
ENST00000453150.1
ENST00000409560.1
MAGEA2B







melanoma antigen family A, 2B







chr19_-_15560730 0.149 ENST00000389282.4
ENST00000263381.7
WIZ

widely interspaced zinc finger motifs

chr19_+_41305330 0.147 ENST00000593972.1
EGLN2
egl-9 family hypoxia-inducible factor 2
chr17_-_58156273 0.147 ENST00000593228.1
ENST00000585976.1
ENST00000593097.1
ENST00000184956.6
HEATR6



HEAT repeat containing 6



chr11_-_59436453 0.146 ENST00000300146.9
PATL1
protein associated with topoisomerase II homolog 1 (yeast)
chr1_+_154975258 0.144 ENST00000417934.2
ZBTB7B
zinc finger and BTB domain containing 7B
chr22_+_38321840 0.144 ENST00000454685.1
MICALL1
MICAL-like 1
chr2_-_242576864 0.143 ENST00000407315.1
THAP4
THAP domain containing 4
chr6_-_44281043 0.143 ENST00000244571.4
AARS2
alanyl-tRNA synthetase 2, mitochondrial
chr5_+_151151471 0.143 ENST00000394123.3
ENST00000543466.1
G3BP1

GTPase activating protein (SH3 domain) binding protein 1

chr22_-_36357671 0.138 ENST00000408983.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr17_+_6926339 0.138 ENST00000293805.5
BCL6B
B-cell CLL/lymphoma 6, member B
chr5_+_151151504 0.137 ENST00000356245.3
ENST00000507878.2
G3BP1

GTPase activating protein (SH3 domain) binding protein 1

chr20_+_34894247 0.137 ENST00000373913.3
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr4_-_103940791 0.135 ENST00000510559.1
ENST00000394789.3
ENST00000296422.7
SLC9B1


solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1


chr2_+_219264762 0.134 ENST00000452977.1
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr19_+_41305612 0.132 ENST00000594380.1
ENST00000593397.1
ENST00000601733.1
EGLN2


egl-9 family hypoxia-inducible factor 2


chr14_+_105155925 0.132 ENST00000330634.7
ENST00000398337.4
ENST00000392634.4
INF2


inverted formin, FH2 and WH2 domain containing


chr17_+_6926381 0.131 ENST00000576705.1
BCL6B
B-cell CLL/lymphoma 6, member B
chr4_+_75230853 0.131 ENST00000244869.2
EREG
epiregulin
chr1_-_155947951 0.130 ENST00000313695.7
ENST00000497907.1
ARHGEF2

Rho/Rac guanine nucleotide exchange factor (GEF) 2

chr14_-_69444957 0.129 ENST00000556571.1
ENST00000553659.1
ENST00000555616.1
ACTN1


actinin, alpha 1


chr9_+_132427883 0.129 ENST00000372469.4
PRRX2
paired related homeobox 2
chr8_+_144371773 0.128 ENST00000523891.1
ZNF696
zinc finger protein 696
chr17_+_38474489 0.127 ENST00000394089.2
ENST00000425707.3
RARA

retinoic acid receptor, alpha

chr17_-_77005860 0.125 ENST00000591773.1
ENST00000588611.1
ENST00000586916.2
ENST00000592033.1
ENST00000588075.1
ENST00000302345.2
ENST00000591811.1
CANT1






calcium activated nucleotidase 1






chr17_-_79817091 0.125 ENST00000570907.1
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr16_+_1728305 0.125 ENST00000569765.1
HN1L
hematological and neurological expressed 1-like
chr5_+_125758865 0.124 ENST00000542322.1
ENST00000544396.1
GRAMD3

GRAM domain containing 3

chr12_-_44152551 0.123 ENST00000416848.2
ENST00000550784.1
ENST00000547156.1
ENST00000549868.1
ENST00000553166.1
ENST00000551923.1
ENST00000431332.3
ENST00000344862.5
PUS7L







pseudouridylate synthase 7 homolog (S. cerevisiae)-like







chr12_+_96588279 0.123 ENST00000552142.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr11_+_66886717 0.122 ENST00000398645.2
KDM2A
lysine (K)-specific demethylase 2A
chr5_+_125758813 0.122 ENST00000285689.3
ENST00000515200.1
GRAMD3

GRAM domain containing 3

chr19_+_46009837 0.122 ENST00000589627.1
VASP
vasodilator-stimulated phosphoprotein
chr7_+_43152212 0.121 ENST00000453890.1
HECW1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr16_+_28834303 0.121 ENST00000340394.8
ENST00000325215.6
ENST00000395547.2
ENST00000336783.4
ENST00000382686.4
ENST00000564304.1
ATXN2L





ataxin 2-like





chr11_-_9286921 0.119 ENST00000328194.3
DENND5A
DENN/MADD domain containing 5A
chr14_-_105635090 0.119 ENST00000331782.3
ENST00000347004.2
JAG2

jagged 2

chr1_-_150944411 0.118 ENST00000368949.4
CERS2
ceramide synthase 2
chr22_+_46449674 0.112 ENST00000381051.2
FLJ27365
hsa-mir-4763
chr5_+_78908233 0.111 ENST00000453514.1
ENST00000423041.2
ENST00000504233.1
ENST00000428308.2
PAPD4



PAP associated domain containing 4



chr7_+_43152191 0.110 ENST00000395891.2
HECW1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr5_-_159766528 0.110 ENST00000505287.2
CCNJL
cyclin J-like
chr19_+_41305627 0.110 ENST00000593525.1
EGLN2
egl-9 family hypoxia-inducible factor 2
chr2_+_234104079 0.110 ENST00000417661.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr10_+_102758105 0.109 ENST00000429732.1
LZTS2
leucine zipper, putative tumor suppressor 2
chr16_+_28834531 0.109 ENST00000570200.1
ATXN2L
ataxin 2-like
chr7_+_94537247 0.108 ENST00000422324.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr9_-_14314066 0.107 ENST00000397575.3
NFIB
nuclear factor I/B
chr16_+_30969055 0.107 ENST00000452917.1
SETD1A
SET domain containing 1A
chr12_-_95044309 0.106 ENST00000261226.4
TMCC3
transmembrane and coiled-coil domain family 3
chr12_+_44152740 0.106 ENST00000440781.2
ENST00000431837.1
ENST00000550616.1
ENST00000448290.2
ENST00000551736.1
IRAK4




interleukin-1 receptor-associated kinase 4




chr2_+_242577097 0.105 ENST00000419606.1
ENST00000474739.2
ENST00000396411.3
ENST00000425239.1
ENST00000400771.3
ENST00000430617.2
ATG4B





autophagy related 4B, cysteine peptidase





chr17_-_76732928 0.104 ENST00000589768.1
CYTH1
cytohesin 1
chr1_-_113249948 0.104 ENST00000339083.7
ENST00000369642.3
RHOC

ras homolog family member C

chr17_+_80376194 0.103 ENST00000337014.6
HEXDC
hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing
chr19_-_19051993 0.102 ENST00000594794.1
ENST00000355887.6
ENST00000392351.3
ENST00000596482.1
HOMER3



homer homolog 3 (Drosophila)



chr8_+_144816303 0.101 ENST00000533004.1
FAM83H-AS1
FAM83H antisense RNA 1 (head to head)
chr5_+_78908388 0.101 ENST00000296783.3
PAPD4
PAP associated domain containing 4
chr4_+_671711 0.101 ENST00000400159.2
MYL5
myosin, light chain 5, regulatory
chr16_+_67143880 0.101 ENST00000219139.3
ENST00000566026.1
C16orf70

chromosome 16 open reading frame 70

chr22_-_44894178 0.100 ENST00000341255.3
LDOC1L
leucine zipper, down-regulated in cancer 1-like
chr19_-_48867291 0.100 ENST00000435956.3
TMEM143
transmembrane protein 143
chr19_+_41305740 0.099 ENST00000596517.1
EGLN2
egl-9 family hypoxia-inducible factor 2
chr8_+_145064233 0.097 ENST00000529301.1
ENST00000395068.4
GRINA

glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)

chrX_-_14891150 0.097 ENST00000452869.1
ENST00000398334.1
ENST00000324138.3
FANCB


Fanconi anemia, complementation group B


chr2_-_61765315 0.097 ENST00000406957.1
ENST00000401558.2
XPO1

exportin 1 (CRM1 homolog, yeast)

chr17_+_38296576 0.096 ENST00000264645.7
CASC3
cancer susceptibility candidate 3
chr6_+_37475109 0.096 ENST00000570443.2
RP1-153P14.8
RP1-153P14.8
chr10_+_127661942 0.095 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
FANK1


fibronectin type III and ankyrin repeat domains 1


chr4_-_38666430 0.093 ENST00000436901.1
AC021860.1
Uncharacterized protein
chr2_+_242577027 0.092 ENST00000402096.1
ENST00000404914.3
ATG4B

autophagy related 4B, cysteine peptidase

chr14_+_76044934 0.091 ENST00000238667.4
FLVCR2
feline leukemia virus subgroup C cellular receptor family, member 2
chr19_-_15442701 0.089 ENST00000594841.1
ENST00000601941.1
BRD4

bromodomain containing 4

chr16_+_67143828 0.089 ENST00000563853.2
ENST00000569914.1
ENST00000569600.1
C16orf70


chromosome 16 open reading frame 70


chr14_-_54418598 0.089 ENST00000609748.1
ENST00000558961.1
BMP4

bone morphogenetic protein 4

chr7_-_128045984 0.088 ENST00000470772.1
ENST00000480861.1
ENST00000496200.1
IMPDH1


IMP (inosine 5'-monophosphate) dehydrogenase 1


chr6_+_7107830 0.088 ENST00000379933.3
RREB1
ras responsive element binding protein 1
chr22_-_37976082 0.088 ENST00000215886.4
LGALS2
lectin, galactoside-binding, soluble, 2
chr6_-_86352982 0.086 ENST00000369622.3
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr2_+_28974531 0.084 ENST00000420282.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr6_+_37321823 0.084 ENST00000487950.1
ENST00000469731.1
RNF8

ring finger protein 8, E3 ubiquitin protein ligase

chr8_+_28748765 0.081 ENST00000355231.5
HMBOX1
homeobox containing 1
chr19_+_36157715 0.081 ENST00000379013.2
ENST00000222275.2
UPK1A

uroplakin 1A

chr1_-_113249734 0.079 ENST00000484054.3
ENST00000369636.2
ENST00000369637.1
ENST00000285735.2
ENST00000369638.2
RHOC




ras homolog family member C




chr9_-_139293249 0.078 ENST00000298532.2
SNAPC4
small nuclear RNA activating complex, polypeptide 4, 190kDa
chr1_+_110091189 0.078 ENST00000369851.4
GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr17_-_1733114 0.077 ENST00000305513.7
SMYD4
SET and MYND domain containing 4
chr17_+_78193443 0.075 ENST00000577155.1
SLC26A11
solute carrier family 26 (anion exchanger), member 11
chr1_-_113249678 0.075 ENST00000369633.2
ENST00000425265.2
ENST00000369632.2
ENST00000436685.2
RHOC



ras homolog family member C



chr13_-_108867846 0.074 ENST00000442234.1
LIG4
ligase IV, DNA, ATP-dependent
chr12_+_132413765 0.073 ENST00000376649.3
ENST00000322060.5
PUS1

pseudouridylate synthase 1

chr15_+_77713299 0.073 ENST00000559099.1
HMG20A
high mobility group 20A
chr19_-_19051927 0.072 ENST00000600077.1
HOMER3
homer homolog 3 (Drosophila)
chr14_+_74353320 0.072 ENST00000540593.1
ENST00000555730.1
ZNF410

zinc finger protein 410

chr16_-_28503080 0.072 ENST00000565316.1
ENST00000565778.1
ENST00000357857.9
ENST00000568558.1
ENST00000357806.7
CLN3




ceroid-lipofuscinosis, neuronal 3




chr2_+_223289208 0.071 ENST00000321276.7
SGPP2
sphingosine-1-phosphate phosphatase 2
chr12_-_48226897 0.071 ENST00000434070.1
HDAC7
histone deacetylase 7
chr12_+_96588143 0.071 ENST00000228741.3
ENST00000547249.1
ELK3

ELK3, ETS-domain protein (SRF accessory protein 2)

chr6_+_37321748 0.071 ENST00000373479.4
ENST00000394443.4
RNF8

ring finger protein 8, E3 ubiquitin protein ligase

chr12_+_132413739 0.071 ENST00000443358.2
PUS1
pseudouridylate synthase 1
chr18_+_9334786 0.070 ENST00000581641.1
TWSG1
twisted gastrulation BMP signaling modulator 1
chr16_+_69958887 0.070 ENST00000568684.1
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr6_+_7541808 0.069 ENST00000379802.3
DSP
desmoplakin
chr7_+_75932863 0.069 ENST00000429938.1
HSPB1
heat shock 27kDa protein 1
chr2_-_85637459 0.068 ENST00000409921.1
CAPG
capping protein (actin filament), gelsolin-like
chr21_-_36259445 0.068 ENST00000399240.1
RUNX1
runt-related transcription factor 1
chr2_-_230786619 0.068 ENST00000389045.3
ENST00000409677.1
TRIP12

thyroid hormone receptor interactor 12

chr13_+_28813645 0.068 ENST00000282391.5
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr3_+_184032919 0.068 ENST00000427845.1
ENST00000342981.4
ENST00000319274.6
EIF4G1


eukaryotic translation initiation factor 4 gamma, 1


chr10_-_112064665 0.067 ENST00000369603.5
SMNDC1
survival motor neuron domain containing 1
chrX_+_37545012 0.067 ENST00000378616.3
XK
X-linked Kx blood group (McLeod syndrome)
chr3_-_137834436 0.066 ENST00000327532.2
ENST00000467030.1
DZIP1L

DAZ interacting zinc finger protein 1-like

chr5_-_179227540 0.066 ENST00000520875.1
MGAT4B
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr14_+_74353508 0.066 ENST00000324593.6
ENST00000557495.1
ENST00000556659.1
ENST00000557363.1
ZNF410



zinc finger protein 410



chr18_+_9334755 0.065 ENST00000262120.5
TWSG1
twisted gastrulation BMP signaling modulator 1
chr11_-_61196858 0.065 ENST00000413184.2
CPSF7
cleavage and polyadenylation specific factor 7, 59kDa
chr11_-_61197406 0.064 ENST00000541963.1
ENST00000477890.2
CPSF7

cleavage and polyadenylation specific factor 7, 59kDa

chr12_-_49351148 0.064 ENST00000539611.1
ENST00000398092.4
ARF3
RP11-302B13.5
ADP-ribosylation factor 3
ADP-ribosylation factor 3
chr7_+_95401877 0.064 ENST00000524053.1
ENST00000324972.6
ENST00000537881.1
ENST00000437599.1
ENST00000359388.4
ENST00000413338.1
DYNC1I1





dynein, cytoplasmic 1, intermediate chain 1





chr7_+_91570240 0.063 ENST00000394564.1
AKAP9
A kinase (PRKA) anchor protein 9
chr3_+_141205852 0.063 ENST00000286364.3
ENST00000452898.1
RASA2

RAS p21 protein activator 2

chr16_+_30935418 0.063 ENST00000338343.4
FBXL19
F-box and leucine-rich repeat protein 19
chr16_-_28503357 0.062 ENST00000333496.9
ENST00000561505.1
ENST00000567963.1
ENST00000354630.5
ENST00000355477.5
ENST00000357076.5
ENST00000565688.1
ENST00000359984.7
CLN3







ceroid-lipofuscinosis, neuronal 3







chr6_+_7541845 0.062 ENST00000418664.2
DSP
desmoplakin
chr5_-_142065612 0.061 ENST00000360966.5
ENST00000411960.1
FGF1

fibroblast growth factor 1 (acidic)

chr5_-_98262240 0.060 ENST00000284049.3
CHD1
chromodomain helicase DNA binding protein 1
chr12_+_62654119 0.060 ENST00000353364.3
ENST00000549523.1
ENST00000280377.5
USP15


ubiquitin specific peptidase 15


chr14_+_74353574 0.060 ENST00000442160.3
ENST00000555044.1
ZNF410

zinc finger protein 410

chr20_-_58508359 0.059 ENST00000446834.1
SYCP2
synaptonemal complex protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0042660 positive regulation of cell fate specification(GO:0042660)
0.1 0.5 GO:0002432 granuloma formation(GO:0002432)
0.1 0.7 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.1 0.3 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.3 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 0.9 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.6 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.2 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.1 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.3 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.2 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.1 GO:0042700 luteinizing hormone signaling pathway(GO:0042700)
0.0 0.3 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 1.0 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.1 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0 0.1 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.3 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.1 GO:1905045 Schwann cell proliferation involved in axon regeneration(GO:0014011) negative regulation of Schwann cell migration(GO:1900148) regulation of Schwann cell proliferation involved in axon regeneration(GO:1905044) negative regulation of Schwann cell proliferation involved in axon regeneration(GO:1905045)
0.0 0.5 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.2 GO:0051697 protein delipidation(GO:0051697)
0.0 0.4 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.0 0.2 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.1 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.0 0.2 GO:0071484 cellular response to light intensity(GO:0071484)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.2 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.1 GO:0048389 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) deltoid tuberosity development(GO:0035993) intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) pattern specification involved in mesonephros development(GO:0061227) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.1 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.1 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.2 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.0 GO:1904875 regulation of DNA ligase activity(GO:1904875)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.0 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.0 0.6 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.1 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.0 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.0 GO:0043385 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.3 GO:0006750 glutathione biosynthetic process(GO:0006750)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.8 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.1 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.3 GO:0004913 interleukin-4 receptor activity(GO:0004913)
0.1 0.3 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.1 0.2 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.1 0.6 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.8 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 0.2 GO:0004423 iduronate-2-sulfatase activity(GO:0004423)
0.1 1.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.3 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.2 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.7 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.6 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.3 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 1.0 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.6 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.6 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.9 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.0 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.7 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.1 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor