Motif ID: RORC

Z-value: 0.219


Transcription factors associated with RORC:

Gene SymbolEntrez IDGene Name
RORC ENSG00000143365.12 RORC

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
RORChg19_v2_chr1_-_151804314_151804348-0.924.3e-04Click!


Activity profile for motif RORC.

activity profile for motif RORC


Sorted Z-values histogram for motif RORC

Sorted Z-values for motif RORC



Network of associatons between targets according to the STRING database.



First level regulatory network of RORC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_13061894 0.253 ENST00000540125.1
 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr10_-_105845674 0.196 ENST00000353479.5
ENST00000369733.3
 COL17A1

collagen, type XVII, alpha 1

chr14_-_23451845 0.176 ENST00000262713.2
 AJUBA
ajuba LIM protein
chr1_-_211752073 0.125 ENST00000367001.4
 SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr10_-_105845536 0.108 ENST00000393211.3
 COL17A1
collagen, type XVII, alpha 1
chr17_-_48785216 0.093 ENST00000285243.6
 ANKRD40
ankyrin repeat domain 40
chr14_-_23451467 0.087 ENST00000361265.4
ENST00000555074.1
 AJUBA
RP11-298I3.5
ajuba LIM protein
RP11-298I3.5
chr7_+_112063192 0.086 ENST00000005558.4
 IFRD1
interferon-related developmental regulator 1
chr14_-_54418598 0.080 ENST00000609748.1
ENST00000558961.1
 BMP4

bone morphogenetic protein 4

chr8_+_124780672 0.073 ENST00000521166.1
ENST00000334705.7
 FAM91A1

family with sequence similarity 91, member A1

chr12_+_93963590 0.073 ENST00000340600.2
 SOCS2
suppressor of cytokine signaling 2
chr1_+_171810606 0.071 ENST00000358155.4
ENST00000367733.2
ENST00000355305.5
ENST00000367731.1
 DNM3



dynamin 3



chr7_-_128415844 0.070 ENST00000249389.2
 OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chr9_-_110251836 0.067 ENST00000374672.4
 KLF4
Kruppel-like factor 4 (gut)
chr3_-_65583561 0.062 ENST00000460329.2
 MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr7_-_43965937 0.060 ENST00000455877.1
ENST00000223341.7
ENST00000447717.3
ENST00000426198.1
 URGCP



upregulator of cell proliferation



chr12_+_93964158 0.060 ENST00000549206.1
 SOCS2
suppressor of cytokine signaling 2
chr10_-_103578162 0.060 ENST00000361464.3
ENST00000357797.5
ENST00000370094.3
 MGEA5


meningioma expressed antigen 5 (hyaluronidase)


chr4_+_169633310 0.059 ENST00000510998.1
 PALLD
palladin, cytoskeletal associated protein
chr14_-_68157084 0.057 ENST00000557564.1
 RP11-1012A1.4
RP11-1012A1.4
chr18_-_23671139 0.057 ENST00000579061.1
ENST00000542420.2
 SS18

synovial sarcoma translocation, chromosome 18

chr6_-_111927062 0.055 ENST00000359831.4
 TRAF3IP2
TRAF3 interacting protein 2
chr1_-_150207017 0.054 ENST00000369119.3
 ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr1_+_205197304 0.051 ENST00000358024.3
 TMCC2
transmembrane and coiled-coil domain family 2
chr1_-_240906911 0.048 ENST00000431139.2
 RP11-80B9.4
RP11-80B9.4
chr12_+_56414795 0.048 ENST00000431367.2
 IKZF4
IKAROS family zinc finger 4 (Eos)
chr10_-_103578182 0.044 ENST00000439817.1
 MGEA5
meningioma expressed antigen 5 (hyaluronidase)
chr19_-_7698599 0.042 ENST00000311069.5
 PCP2
Purkinje cell protein 2
chr14_-_104408645 0.042 ENST00000557640.1
 RD3L
retinal degeneration 3-like
chr1_-_157069590 0.036 ENST00000454449.2
 ETV3L
ets variant 3-like
chr2_+_162016827 0.032 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
 TANK


TRAF family member-associated NFKB activator


chr16_-_67514982 0.031 ENST00000565835.1
ENST00000540149.1
ENST00000290949.3
 ATP6V0D1


ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1


chr4_+_110749143 0.031 ENST00000317735.4
 RRH
retinal pigment epithelium-derived rhodopsin homolog
chr11_-_10822029 0.029 ENST00000528839.1
 EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr2_-_148778323 0.029 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
 ORC4



origin recognition complex, subunit 4



chr1_+_236849754 0.028 ENST00000542672.1
ENST00000366578.4
 ACTN2

actinin, alpha 2

chr1_+_114447763 0.028 ENST00000369563.3
 DCLRE1B
DNA cross-link repair 1B
chr10_-_121296045 0.027 ENST00000392865.1
 RGS10
regulator of G-protein signaling 10
chr19_-_46580352 0.026 ENST00000601672.1
 IGFL4
IGF-like family member 4
chr2_+_160590469 0.025 ENST00000409591.1
 MARCH7
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
chr2_+_162016804 0.025 ENST00000392749.2
ENST00000440506.1
 TANK

TRAF family member-associated NFKB activator

chr4_-_87770416 0.023 ENST00000273905.6
 SLC10A6
solute carrier family 10 (sodium/bile acid cotransporter), member 6
chr17_-_37764128 0.023 ENST00000302584.4
 NEUROD2
neuronal differentiation 2
chr1_-_185286461 0.020 ENST00000367498.3
 IVNS1ABP
influenza virus NS1A binding protein
chr10_+_102295616 0.019 ENST00000299163.6
 HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr8_-_116673894 0.019 ENST00000395713.2
 TRPS1
trichorhinophalangeal syndrome I
chr17_+_47439733 0.018 ENST00000507337.1
 RP11-1079K10.3
RP11-1079K10.3
chr14_+_21785693 0.018 ENST00000382933.4
ENST00000557351.1
 RPGRIP1

retinitis pigmentosa GTPase regulator interacting protein 1

chr16_-_69385681 0.018 ENST00000288025.3
 TMED6
transmembrane emp24 protein transport domain containing 6
chr2_+_162016916 0.018 ENST00000405852.1
 TANK
TRAF family member-associated NFKB activator
chr21_+_17553910 0.016 ENST00000428669.2
 LINC00478
long intergenic non-protein coding RNA 478
chr19_-_8567505 0.016 ENST00000600262.1
 PRAM1
PML-RARA regulated adaptor molecule 1
chr3_+_185304059 0.015 ENST00000427465.2
 SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr6_-_46922659 0.013 ENST00000265417.7
 GPR116
G protein-coupled receptor 116
chr19_-_7697857 0.012 ENST00000598935.1
 PCP2
Purkinje cell protein 2
chr1_-_145826450 0.012 ENST00000462900.2
 GPR89A
G protein-coupled receptor 89A
chr16_+_30937213 0.011 ENST00000427128.1
 FBXL19
F-box and leucine-rich repeat protein 19
chr3_+_45986511 0.011 ENST00000458629.1
ENST00000457814.1
 CXCR6

chemokine (C-X-C motif) receptor 6

chr19_+_38924316 0.009 ENST00000355481.4
ENST00000360985.3
ENST00000359596.3
 RYR1


ryanodine receptor 1 (skeletal)


chr4_-_159094194 0.008 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
 FAM198B


family with sequence similarity 198, member B


chr4_-_1188922 0.008 ENST00000515004.1
ENST00000502483.1
 SPON2

spondin 2, extracellular matrix protein

chr12_+_56623827 0.007 ENST00000424625.1
ENST00000419753.1
ENST00000454355.2
ENST00000417965.1
ENST00000436633.1
 SLC39A5




solute carrier family 39 (zinc transporter), member 5




chr7_+_20686946 0.006 ENST00000443026.2
ENST00000406935.1
 ABCB5

ATP-binding cassette, sub-family B (MDR/TAP), member 5

chr7_-_141541221 0.006 ENST00000350549.3
ENST00000438520.1
 PRSS37

protease, serine, 37

chr16_+_16326352 0.006 ENST00000399336.4
ENST00000263012.6
ENST00000538468.1
 NOMO3


NODAL modulator 3


chr22_-_32022280 0.005 ENST00000442379.1
 PISD
phosphatidylserine decarboxylase
chr2_-_30144432 0.004 ENST00000389048.3
 ALK
anaplastic lymphoma receptor tyrosine kinase
chr12_+_56624436 0.004 ENST00000266980.4
ENST00000437277.1
 SLC39A5

solute carrier family 39 (zinc transporter), member 5

chrX_-_102531717 0.004 ENST00000372680.1
 TCEAL5
transcription elongation factor A (SII)-like 5
chr17_+_44679808 0.004 ENST00000571172.1
 NSF
N-ethylmaleimide-sensitive factor
chr13_+_109248500 0.004 ENST00000356711.2
 MYO16
myosin XVI
chrX_-_49089771 0.004 ENST00000376251.1
ENST00000323022.5
ENST00000376265.2
 CACNA1F


calcium channel, voltage-dependent, L type, alpha 1F subunit


chr6_+_89855765 0.003 ENST00000275072.4
 PM20D2
peptidase M20 domain containing 2
chr11_-_64527425 0.002 ENST00000377432.3
 PYGM
phosphorylase, glycogen, muscle
chr14_-_104408032 0.002 ENST00000455348.2
 RD3L
retinal degeneration 3-like
chr17_-_10707410 0.002 ENST00000581851.1
 LINC00675
long intergenic non-protein coding RNA 675
chr12_-_39734783 0.001 ENST00000552961.1
 KIF21A
kinesin family member 21A
chr20_-_44007014 0.001 ENST00000372726.3
ENST00000537995.1
 TP53TG5

TP53 target 5

chr19_+_55385731 0.001 ENST00000469767.1
ENST00000355524.3
ENST00000391725.3
ENST00000345937.4
ENST00000353758.4
ENST00000359272.4
ENST00000391723.3
ENST00000391724.3
 FCAR







Fc fragment of IgA, receptor for







chr7_+_127527965 0.000 ENST00000486037.1
 SND1
staphylococcal nuclease and tudor domain containing 1
chr19_-_8567478 0.000 ENST00000255612.3
 PRAM1
PML-RARA regulated adaptor molecule 1
chr17_-_46623441 0.000 ENST00000330070.4
 HOXB2
homeobox B2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0098843 postsynaptic endocytic zone(GO:0098843) postsynaptic endocytic zone membrane(GO:0098844)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.0 0.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)