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• Activity deltas table
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• Motifs sorted by significance (text)
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Motif ID: RFX5

Z-value: 0.427

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_208417620	0.560	ENST00000367033.3	PLXNA2	plexin A2
chr6_+_32821924	0.534	ENST00000374859.2 ENST00000453265.2	PSMB9	proteasome (prosome, macropain) subunit, beta type, 9
chr6_+_32812568	0.501	ENST00000414474.1	PSMB9	proteasome (prosome, macropain) subunit, beta type, 9
chr6_-_30181156	0.466	ENST00000418026.1 ENST00000416596.1 ENST00000453195.1	TRIM26	tripartite motif containing 26
chr6_-_30181133	0.455	ENST00000454678.2 ENST00000434785.1	TRIM26	tripartite motif containing 26
chr11_+_45868957	0.422	ENST00000443527.2	CRY2	cryptochrome 2 (photolyase-like)
chr6_-_32821599	0.341	ENST00000354258.4	TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr11_+_66624527	0.297	ENST00000393952.3	LRFN4	leucine rich repeat and fibronectin type III domain containing 4
chr11_-_118436707	0.263	ENST00000264020.2 ENST00000264021.3	IFT46	intraflagellar transport 46 homolog (Chlamydomonas)
chr6_+_26458171	0.239	ENST00000493173.1 ENST00000541522.1 ENST00000429381.1 ENST00000469185.1	BTN2A1	butyrophilin, subfamily 2, member A1
chr6_+_26458152	0.235	ENST00000312541.5	BTN2A1	butyrophilin, subfamily 2, member A1
chr11_-_118436606	0.218	ENST00000530872.1	IFT46	intraflagellar transport 46 homolog (Chlamydomonas)
chr19_+_19496728	0.176	ENST00000537887.1 ENST00000417582.2	GATAD2A	GATA zinc finger domain containing 2A
chr16_-_74808710	0.173	ENST00000219368.3 ENST00000544337.1	FA2H	fatty acid 2-hydroxylase
chr17_+_38137050	0.153	ENST00000264639.4	PSMD3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr1_+_114473350	0.151	ENST00000503968.1	HIPK1	homeodomain interacting protein kinase 1
chr17_+_38137073	0.143	ENST00000541736.1	PSMD3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr22_-_30987837	0.138	ENST00000335214.6	PES1	pescadillo ribosomal biogenesis factor 1
chr1_-_202936394	0.138	ENST00000367249.4	CYB5R1	cytochrome b5 reductase 1
chr1_+_249132512	0.123	ENST00000505503.1	ZNF672	zinc finger protein 672
chr6_-_24667180	0.120	ENST00000545995.1	TDP2	tyrosyl-DNA phosphodiesterase 2
chrX_-_40594755	0.117	ENST00000324817.1	MED14	mediator complex subunit 14
chr6_-_32784687	0.105	ENST00000447394.1 ENST00000438763.2	HLA-DOB	major histocompatibility complex, class II, DO beta
chr19_+_50031547	0.102	ENST00000597801.1	RCN3	reticulocalbin 3, EF-hand calcium binding domain
chr6_-_24666819	0.101	ENST00000341060.3	TDP2	tyrosyl-DNA phosphodiesterase 2
chr3_+_43328004	0.091	ENST00000454177.1 ENST00000429705.2 ENST00000296088.7 ENST00000437827.1	SNRK	SNF related kinase
chrX_-_71933888	0.090	ENST00000373542.4 ENST00000339490.3 ENST00000541944.1 ENST00000373539.3 ENST00000373545.3	PHKA1	phosphorylase kinase, alpha 1 (muscle)
chr12_-_123565834	0.081	ENST00000546049.1	PITPNM2	phosphatidylinositol transfer protein, membrane-associated 2
chr6_+_26383318	0.075	ENST00000469230.1 ENST00000490025.1 ENST00000356709.4 ENST00000352867.2 ENST00000493275.1 ENST00000472507.1 ENST00000482536.1 ENST00000432533.2 ENST00000482842.1	BTN2A2	butyrophilin, subfamily 2, member A2
chr6_-_30658745	0.075	ENST00000376420.5 ENST00000376421.5	NRM	nurim (nuclear envelope membrane protein)
chr10_+_14880364	0.074	ENST00000441647.1	HSPA14	heat shock 70kDa protein 14
chr1_+_36549676	0.070	ENST00000207457.3	TEKT2	tektin 2 (testicular)
chr19_-_51014345	0.067	ENST00000391815.3 ENST00000594350.1 ENST00000601423.1	JOSD2	Josephin domain containing 2
chr10_+_14880157	0.065	ENST00000378372.3	HSPA14	heat shock 70kDa protein 14
chr19_+_19496624	0.062	ENST00000494516.2 ENST00000360315.3 ENST00000252577.5	GATAD2A	GATA zinc finger domain containing 2A
chr6_+_26440700	0.061	ENST00000494393.1 ENST00000482451.1 ENST00000244519.2 ENST00000339789.4 ENST00000471353.1 ENST00000361232.3 ENST00000487627.1 ENST00000496719.1 ENST00000490254.1 ENST00000487272.1	BTN3A3	butyrophilin, subfamily 3, member A3
chr1_+_46049706	0.061	ENST00000527470.1 ENST00000525515.1 ENST00000537798.1 ENST00000402363.3 ENST00000528238.1 ENST00000350030.3 ENST00000470768.1 ENST00000372052.4 ENST00000351223.3	NASP	nuclear autoantigenic sperm protein (histone-binding)
chr4_-_143226979	0.061	ENST00000514525.1	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa
chr4_-_143227088	0.058	ENST00000511838.1	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa
chr1_+_150254936	0.058	ENST00000447007.1 ENST00000369095.1 ENST00000369094.1	C1orf51	chromosome 1 open reading frame 51
chr1_+_249132462	0.057	ENST00000306562.3	ZNF672	zinc finger protein 672
chr6_+_26383404	0.057	ENST00000416795.2 ENST00000494184.1	BTN2A2	butyrophilin, subfamily 2, member A2
chr17_-_19265982	0.057	ENST00000268841.6 ENST00000261499.4 ENST00000575478.1	B9D1	B9 protein domain 1
chr2_-_242088850	0.054	ENST00000358649.4 ENST00000452907.1 ENST00000403638.3 ENST00000539818.1 ENST00000415234.1 ENST00000234040.4	PASK	PAS domain containing serine/threonine kinase
chr8_+_101170257	0.053	ENST00000251809.3	SPAG1	sperm associated antigen 1
chr11_-_72433346	0.048	ENST00000334211.8	ARAP1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr4_-_83719884	0.040	ENST00000282709.4 ENST00000273908.4	SCD5	stearoyl-CoA desaturase 5
chr17_-_19266045	0.037	ENST00000395616.3	B9D1	B9 protein domain 1
chr6_+_26365387	0.036	ENST00000532865.1 ENST00000530653.1 ENST00000527417.1	BTN3A2	butyrophilin, subfamily 3, member A2
chr2_-_201599892	0.033	ENST00000452787.1	AC007163.3	AC007163.3
chr10_-_14880002	0.029	ENST00000465530.1	CDNF	cerebral dopamine neurotrophic factor
chr17_-_19265855	0.029	ENST00000440841.1 ENST00000395615.1 ENST00000461069.2	B9D1	B9 protein domain 1
chr16_+_67381289	0.022	ENST00000435835.3	LRRC36	leucine rich repeat containing 36
chr19_+_36103631	0.013	ENST00000203166.5 ENST00000379045.2	HAUS5	HAUS augmin-like complex, subunit 5
chr13_-_47012325	0.013	ENST00000409879.2	KIAA0226L	KIAA0226-like
chr6_-_32557610	0.010	ENST00000360004.5	HLA-DRB1	major histocompatibility complex, class II, DR beta 1
chr1_+_85527987	0.010	ENST00000326813.8 ENST00000294664.6 ENST00000528899.1	WDR63	WD repeat domain 63
chr19_-_6057282	0.009	ENST00000592281.1	RFX2	regulatory factor X, 2 (influences HLA class II expression)
chr4_+_88529681	0.008	ENST00000399271.1	DSPP	dentin sialophosphoprotein
chr11_-_85430088	0.007	ENST00000533057.1 ENST00000533892.1	SYTL2	synaptotagmin-like 2
chr16_+_67381263	0.006	ENST00000541146.1 ENST00000563189.1 ENST00000290940.7	LRRC36	leucine rich repeat containing 36
chr6_+_26365443	0.003	ENST00000527422.1 ENST00000356386.2 ENST00000396934.3 ENST00000377708.2 ENST00000396948.1 ENST00000508906.2	BTN3A2	butyrophilin, subfamily 3, member A2
chr6_-_32731299	0.001	ENST00000435145.2 ENST00000437316.2	HLA-DQB2	major histocompatibility complex, class II, DQ beta 2
chr2_+_242089046	0.001	ENST00000407025.1 ENST00000272983.8	PPP1R7	protein phosphatase 1, regulatory subunit 7
chr8_-_98290087	0.001	ENST00000322128.3	TSPYL5	TSPY-like 5

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
0.1	0.3	GO:0046967	cytosol to ER transport(GO:0046967)
0.0	0.6	GO:0060174	limb bud formation(GO:0060174)
0.0	0.9	GO:1902187	negative regulation of viral release from host cell(GO:1902187)
0.0	0.1	GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0	0.1	GO:0051083	'de novo' cotranslational protein folding(GO:0051083)
0.0	0.2	GO:0032286	central nervous system myelin maintenance(GO:0032286)
0.0	0.0	GO:1903966	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0	0.2	GO:0060235	embryonic retina morphogenesis in camera-type eye(GO:0060059) lens induction in camera-type eye(GO:0060235)
0.0	0.1	GO:0007000	nucleolus organization(GO:0007000)
0.0	1.2	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	GO:1990111	spermatoproteasome complex(GO:1990111)
0.0	0.3	GO:0042825	TAP complex(GO:0042825)
0.0	0.6	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.3	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0	0.1	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.5	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.1	GO:0070847	core mediator complex(GO:0070847)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0070260	tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.0	0.3	GO:0046979	TAP2 binding(GO:0046979)
0.0	0.9	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.4	GO:0009881	photoreceptor activity(GO:0009881)
0.0	0.6	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.1	GO:0016316	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0	0.1	GO:0032395	MHC class II receptor activity(GO:0032395)
0.0	0.1	GO:0008158	hedgehog receptor activity(GO:0008158)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.4	PID_CIRCADIAN_PATHWAY	Circadian rhythm pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.6	REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	1.2	REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.3	REACTOME_ER_PHAGOSOME_PATHWAY	Genes involved in ER-Phagosome pathway

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