Motif ID: RFX3_RFX2

Z-value: 0.655

Transcription factors associated with RFX3_RFX2:

Gene SymbolEntrez IDGene Name
RFX2 ENSG00000087903.8 RFX2
RFX3 ENSG00000080298.11 RFX3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
RFX2hg19_v2_chr19_-_6110457_61104720.599.8e-02Click!
RFX3hg19_v2_chr9_-_3489428_3489437-0.442.4e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of RFX3_RFX2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_74648848 0.990 ENST00000409791.1
ENST00000426787.1
ENST00000348227.4
WDR54


WD repeat domain 54


chr14_+_105941118 0.616 ENST00000550577.1
ENST00000538259.2
CRIP2

cysteine-rich protein 2

chr4_-_186733363 0.563 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2


sorbin and SH3 domain containing 2


chr17_-_8079648 0.428 ENST00000449985.2
ENST00000532998.1
ENST00000437139.2
ENST00000533070.1
ENST00000316425.5
TMEM107




transmembrane protein 107




chr11_-_64885111 0.405 ENST00000528598.1
ENST00000310597.4
ZNHIT2

zinc finger, HIT-type containing 2

chr17_-_8079632 0.390 ENST00000431792.2
TMEM107
transmembrane protein 107
chr3_+_48507210 0.390 ENST00000433541.1
ENST00000422277.2
ENST00000436480.2
ENST00000444177.1
TREX1



three prime repair exonuclease 1



chr19_+_3572925 0.359 ENST00000333651.6
ENST00000417382.1
ENST00000453933.1
ENST00000262949.7
HMG20B



high mobility group 20B



chr17_-_7760779 0.355 ENST00000335155.5
ENST00000575071.1
LSMD1

LSM domain containing 1

chr2_-_15701422 0.345 ENST00000441750.1
ENST00000281513.5
NBAS

neuroblastoma amplified sequence

chr11_+_66360665 0.335 ENST00000310190.4
CCS
copper chaperone for superoxide dismutase
chr17_-_7761256 0.331 ENST00000575208.1
LSMD1
LSM domain containing 1
chr10_+_124030819 0.328 ENST00000260723.4
ENST00000368994.2
BTBD16

BTB (POZ) domain containing 16

chr12_-_110011288 0.327 ENST00000540016.1
ENST00000266839.5
MMAB

methylmalonic aciduria (cobalamin deficiency) cblB type

chr3_-_48470838 0.326 ENST00000358459.4
ENST00000358536.4
PLXNB1

plexin B1

chr6_+_13925318 0.321 ENST00000423553.2
ENST00000537388.1
RNF182

ring finger protein 182

chr19_-_59084647 0.312 ENST00000594234.1
ENST00000596039.1
MZF1

myeloid zinc finger 1

chr19_-_7553889 0.307 ENST00000221480.1
PEX11G
peroxisomal biogenesis factor 11 gamma
chr19_-_46148820 0.300 ENST00000587152.1
EML2
echinoderm microtubule associated protein like 2
chr19_+_17413663 0.298 ENST00000594999.1
MRPL34
mitochondrial ribosomal protein L34
chr6_+_13925098 0.292 ENST00000488300.1
ENST00000544682.1
ENST00000420478.2
RNF182


ring finger protein 182


chr19_-_4535233 0.291 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
PLIN5


perilipin 5


chr3_+_48507621 0.276 ENST00000456089.1
TREX1
three prime repair exonuclease 1
chr19_-_7553852 0.275 ENST00000593547.1
PEX11G
peroxisomal biogenesis factor 11 gamma
chr11_+_111473108 0.274 ENST00000304987.3
SIK2
salt-inducible kinase 2
chr22_-_43485381 0.272 ENST00000331018.7
ENST00000266254.7
ENST00000445824.1
TTLL1


tubulin tyrosine ligase-like family, member 1


chr10_-_134145321 0.271 ENST00000368625.4
ENST00000368619.3
ENST00000456004.1
ENST00000368620.2
STK32C



serine/threonine kinase 32C



chr11_-_27384737 0.264 ENST00000317945.6
CCDC34
coiled-coil domain containing 34
chr6_+_13925170 0.257 ENST00000471906.1
RNF182
ring finger protein 182
chr19_+_3572758 0.257 ENST00000416526.1
HMG20B
high mobility group 20B
chr9_-_131418944 0.256 ENST00000419989.1
ENST00000451652.1
ENST00000372715.2
WDR34


WD repeat domain 34


chr16_-_30773372 0.253 ENST00000545825.1
ENST00000541260.1
C16orf93

chromosome 16 open reading frame 93

chr3_-_48471454 0.253 ENST00000296440.6
ENST00000448774.2
PLXNB1

plexin B1

chr1_-_74663825 0.247 ENST00000370911.3
ENST00000370909.2
ENST00000354431.4
LRRIQ3


leucine-rich repeats and IQ motif containing 3


chr19_-_5680891 0.244 ENST00000309324.4
C19orf70
chromosome 19 open reading frame 70
chr19_+_55851221 0.243 ENST00000255613.3
ENST00000539076.1
SUV420H2
AC020922.1
suppressor of variegation 4-20 homolog 2 (Drosophila)
Uncharacterized protein
chr17_+_260097 0.242 ENST00000360127.6
ENST00000571106.1
ENST00000491373.1
C17orf97


chromosome 17 open reading frame 97


chr3_+_113667354 0.240 ENST00000491556.1
ZDHHC23
zinc finger, DHHC-type containing 23
chr17_-_7761172 0.239 ENST00000333775.5
ENST00000575771.1
LSMD1

LSM domain containing 1

chr22_+_30752606 0.237 ENST00000399824.2
ENST00000405659.1
ENST00000338306.3
CCDC157


coiled-coil domain containing 157


chr16_-_88923285 0.236 ENST00000542788.1
ENST00000569433.1
ENST00000268695.5
ENST00000568311.1
GALNS



galactosamine (N-acetyl)-6-sulfate sulfatase



chr2_-_2334888 0.235 ENST00000428368.2
ENST00000399161.2
MYT1L

myelin transcription factor 1-like

chrX_+_135251783 0.234 ENST00000394153.2
FHL1
four and a half LIM domains 1
chr19_-_51289436 0.231 ENST00000562076.1
CTD-2568A17.1
CTD-2568A17.1
chr19_+_1941117 0.231 ENST00000255641.8
CSNK1G2
casein kinase 1, gamma 2
chr2_+_214149113 0.229 ENST00000331683.5
ENST00000432529.2
ENST00000413312.1
ENST00000272898.7
ENST00000447990.1
SPAG16




sperm associated antigen 16




chr8_+_144798429 0.227 ENST00000338033.4
ENST00000395107.4
ENST00000395108.2
MAPK15


mitogen-activated protein kinase 15


chr15_+_55700741 0.222 ENST00000569691.1
C15orf65
chromosome 15 open reading frame 65
chr6_+_109761898 0.221 ENST00000258052.3
SMPD2
sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
chr20_+_43992094 0.221 ENST00000453003.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chrX_-_106449656 0.220 ENST00000372466.4
ENST00000421752.1
ENST00000372461.3
NUP62CL


nucleoporin 62kDa C-terminal like


chr8_+_144451039 0.220 ENST00000289013.6
RHPN1
rhophilin, Rho GTPase binding protein 1
chr11_-_62473706 0.219 ENST00000403550.1
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr11_-_62473776 0.219 ENST00000278893.7
ENST00000407022.3
ENST00000421906.1
BSCL2


Berardinelli-Seip congenital lipodystrophy 2 (seipin)


chr21_-_44846999 0.218 ENST00000270162.6
SIK1
salt-inducible kinase 1
chr19_-_5680499 0.216 ENST00000587589.1
C19orf70
chromosome 19 open reading frame 70
chr3_-_49142504 0.211 ENST00000306125.6
ENST00000420147.2
QARS

glutaminyl-tRNA synthetase

chr1_+_1550795 0.208 ENST00000520777.1
ENST00000357210.4
ENST00000360522.4
ENST00000378710.3
ENST00000355826.5
ENST00000518681.1
ENST00000505820.2
MIB2






mindbomb E3 ubiquitin protein ligase 2






chr11_-_67276100 0.208 ENST00000301488.3
CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr7_-_1177874 0.207 ENST00000397098.3
ENST00000357429.6
ENST00000397100.2
ENST00000491163.1
C7orf50



chromosome 7 open reading frame 50



chr6_-_41703952 0.207 ENST00000358871.2
ENST00000403298.4
TFEB

transcription factor EB

chr19_+_5681153 0.207 ENST00000577222.1
ENST00000579559.1
RPL36
HSD11B1L
ribosomal protein L36
hydroxysteroid (11-beta) dehydrogenase 1-like
chr11_+_61447845 0.205 ENST00000257215.5
DAGLA
diacylglycerol lipase, alpha
chr17_+_2240775 0.205 ENST00000268989.3
ENST00000426855.2
SGSM2

small G protein signaling modulator 2

chr11_+_844406 0.204 ENST00000397404.1
TSPAN4
tetraspanin 4
chr6_+_46620676 0.203 ENST00000371347.5
ENST00000411689.2
SLC25A27

solute carrier family 25, member 27

chr14_-_75643296 0.201 ENST00000303575.4
TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr4_-_186733119 0.200 ENST00000419063.1
SORBS2
sorbin and SH3 domain containing 2
chr19_-_7990991 0.200 ENST00000318978.4
CTXN1
cortexin 1
chr12_-_64062583 0.196 ENST00000542209.1
DPY19L2
dpy-19-like 2 (C. elegans)
chr11_-_67271723 0.196 ENST00000533391.1
ENST00000534749.1
ENST00000532703.1
PITPNM1


phosphatidylinositol transfer protein, membrane-associated 1


chr19_-_4457776 0.195 ENST00000301281.6
UBXN6
UBX domain protein 6
chr22_-_50746027 0.192 ENST00000425954.1
ENST00000449103.1
PLXNB2

plexin B2

chr18_+_32290218 0.192 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
DTNA


dystrobrevin, alpha


chr19_-_55791058 0.192 ENST00000587959.1
ENST00000585927.1
ENST00000587922.1
ENST00000585698.1
HSPBP1



HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1



chr3_+_186915274 0.191 ENST00000312295.4
RTP1
receptor (chemosensory) transporter protein 1
chr11_-_62473684 0.188 ENST00000448568.2
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr1_+_15736359 0.188 ENST00000375980.4
EFHD2
EF-hand domain family, member D2
chrX_+_135252050 0.186 ENST00000449474.1
ENST00000345434.3
FHL1

four and a half LIM domains 1

chr14_+_74416989 0.186 ENST00000334571.2
ENST00000554920.1
COQ6

coenzyme Q6 monooxygenase

chr16_-_734318 0.183 ENST00000609261.1
ENST00000562111.1
ENST00000562824.1
ENST00000412368.2
ENST00000293882.4
ENST00000454700.1
JMJD8





jumonji domain containing 8





chr6_+_35227449 0.182 ENST00000373953.3
ENST00000440666.2
ENST00000339411.5
ZNF76


zinc finger protein 76


chr11_-_66496430 0.180 ENST00000533211.1
SPTBN2
spectrin, beta, non-erythrocytic 2
chr10_+_81838792 0.180 ENST00000372273.3
TMEM254
transmembrane protein 254
chr3_-_49142178 0.178 ENST00000452739.1
ENST00000414533.1
ENST00000417025.1
QARS


glutaminyl-tRNA synthetase


chr19_-_58874112 0.176 ENST00000311044.3
ENST00000595763.1
ENST00000425453.3
ZNF497


zinc finger protein 497


chr3_+_97483572 0.176 ENST00000335979.2
ENST00000394206.1
ARL6

ADP-ribosylation factor-like 6

chr16_+_2076869 0.175 ENST00000424542.2
ENST00000432365.2
SLC9A3R2

solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2

chr11_+_66278080 0.175 ENST00000318312.7
ENST00000526815.1
ENST00000537537.1
ENST00000525809.1
ENST00000455748.2
ENST00000393994.2
BBS1





Bardet-Biedl syndrome 1





chr19_+_38779778 0.175 ENST00000590738.1
ENST00000587519.2
ENST00000591889.1
SPINT2
CTB-102L5.4

serine peptidase inhibitor, Kunitz type, 2
CTB-102L5.4

chr19_-_59084922 0.174 ENST00000215057.2
ENST00000599369.1
MZF1

myeloid zinc finger 1

chr19_+_50879705 0.173 ENST00000598168.1
ENST00000411902.2
ENST00000253727.5
ENST00000597790.1
ENST00000597130.1
ENST00000599105.1
NR1H2





nuclear receptor subfamily 1, group H, member 2





chr19_-_6393216 0.172 ENST00000595047.1
GTF2F1
general transcription factor IIF, polypeptide 1, 74kDa
chr7_+_150725510 0.170 ENST00000461373.1
ENST00000358849.4
ENST00000297504.6
ENST00000542328.1
ENST00000498578.1
ENST00000356058.4
ENST00000477719.1
ENST00000477092.1
ABCB8







ATP-binding cassette, sub-family B (MDR/TAP), member 8







chr9_+_136325089 0.168 ENST00000291722.7
ENST00000316948.4
ENST00000540581.1
CACFD1


calcium channel flower domain containing 1


chr3_+_46742823 0.168 ENST00000326431.3
TMIE
transmembrane inner ear
chr6_-_41703296 0.167 ENST00000373033.1
TFEB
transcription factor EB
chr1_+_144339738 0.167 ENST00000538264.1
AL592284.1
Protein LOC642441
chr18_+_44526786 0.163 ENST00000245121.5
ENST00000356157.7
KATNAL2

katanin p60 subunit A-like 2

chr1_+_45274154 0.161 ENST00000450269.1
ENST00000453418.1
ENST00000409335.2
BTBD19


BTB (POZ) domain containing 19


chr15_-_90233907 0.159 ENST00000561224.1
PEX11A
peroxisomal biogenesis factor 11 alpha
chr12_-_85430024 0.155 ENST00000547836.1
ENST00000532498.2
TSPAN19

tetraspanin 19

chr19_-_633576 0.155 ENST00000588649.2
POLRMT
polymerase (RNA) mitochondrial (DNA directed)
chr9_+_131085095 0.154 ENST00000372875.3
COQ4
coenzyme Q4
chr6_-_43484718 0.153 ENST00000372422.2
YIPF3
Yip1 domain family, member 3
chr2_+_48667898 0.153 ENST00000281394.4
ENST00000294952.8
PPP1R21

protein phosphatase 1, regulatory subunit 21

chr17_+_54671047 0.152 ENST00000332822.4
NOG
noggin
chr19_-_55791431 0.152 ENST00000593263.1
ENST00000376343.3
HSPBP1

HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1

chr17_+_2240916 0.151 ENST00000574563.1
SGSM2
small G protein signaling modulator 2
chr17_+_9479944 0.149 ENST00000396219.3
ENST00000352665.5
WDR16

WD repeat domain 16

chr4_-_177116772 0.149 ENST00000280191.2
SPATA4
spermatogenesis associated 4
chr6_+_30848829 0.149 ENST00000508317.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr19_+_13842559 0.148 ENST00000586600.1
CCDC130
coiled-coil domain containing 130
chr12_-_110486348 0.147 ENST00000547573.1
ENST00000546651.2
ENST00000551185.2
C12orf76


chromosome 12 open reading frame 76


chr1_+_155178518 0.146 ENST00000316721.4
MTX1
metaxin 1
chr17_-_7760457 0.146 ENST00000576384.1
LSMD1
LSM domain containing 1
chr22_+_31892373 0.144 ENST00000443011.1
ENST00000400289.1
ENST00000444859.1
ENST00000400288.2
SFI1



Sfi1 homolog, spindle assembly associated (yeast)



chr19_+_18263928 0.144 ENST00000222254.8
PIK3R2
phosphoinositide-3-kinase, regulatory subunit 2 (beta)
chr3_+_197677047 0.143 ENST00000448864.1
RPL35A
ribosomal protein L35a
chr16_-_68482440 0.142 ENST00000219334.5
SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr19_-_47249679 0.141 ENST00000263280.6
STRN4
striatin, calmodulin binding protein 4
chr3_+_49027308 0.140 ENST00000383729.4
ENST00000343546.4
P4HTM

prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)

chr6_+_35227247 0.140 ENST00000469195.1
ZNF76
zinc finger protein 76
chr6_+_30848557 0.139 ENST00000460944.2
ENST00000324771.8
DDR1

discoidin domain receptor tyrosine kinase 1

chr2_-_74699770 0.138 ENST00000409710.1
MRPL53
mitochondrial ribosomal protein L53
chr6_+_116575329 0.138 ENST00000430252.2
ENST00000540275.1
ENST00000448740.2
DSE

RP3-486I3.7
dermatan sulfate epimerase

RP3-486I3.7
chr7_+_75508266 0.137 ENST00000006777.6
ENST00000318622.4
RHBDD2

rhomboid domain containing 2

chr3_+_97483366 0.137 ENST00000463745.1
ENST00000462412.1
ARL6

ADP-ribosylation factor-like 6

chr19_+_1450112 0.136 ENST00000590469.1
ENST00000233607.2
ENST00000238483.4
ENST00000590877.1
APC2



adenomatosis polyposis coli 2



chr16_+_28986085 0.136 ENST00000565975.1
ENST00000311008.11
ENST00000323081.8
ENST00000334536.8
SPNS1



spinster homolog 1 (Drosophila)



chr17_+_78389247 0.135 ENST00000520136.2
ENST00000520284.1
ENST00000517795.1
ENST00000523228.1
ENST00000523828.1
ENST00000522200.1
ENST00000521565.1
ENST00000518907.1
ENST00000518644.1
ENST00000518901.1
ENDOV









endonuclease V









chr14_-_48144157 0.135 ENST00000399232.2
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr19_-_17356697 0.134 ENST00000291442.3
NR2F6
nuclear receptor subfamily 2, group F, member 6
chr7_+_150065278 0.134 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
REPIN1


replication initiator 1


chrX_+_48455866 0.133 ENST00000376729.5
ENST00000218056.5
WDR13

WD repeat domain 13

chr6_-_43484621 0.133 ENST00000506469.1
ENST00000503972.1
YIPF3

Yip1 domain family, member 3

chr2_-_178417742 0.132 ENST00000408939.3
TTC30B
tetratricopeptide repeat domain 30B
chr17_+_19314505 0.132 ENST00000461366.1
RNF112
ring finger protein 112
chr16_-_46797149 0.132 ENST00000536476.1
MYLK3
myosin light chain kinase 3
chr5_-_54529415 0.131 ENST00000282572.4
CCNO
cyclin O
chr3_-_49055991 0.131 ENST00000441576.2
ENST00000420952.2
ENST00000341949.4
ENST00000395462.4
DALRD3



DALR anticodon binding domain containing 3



chr14_-_23058063 0.130 ENST00000538631.1
ENST00000543337.1
ENST00000250498.4
DAD1


defender against cell death 1


chr1_-_36916011 0.130 ENST00000356637.5
ENST00000354267.3
ENST00000235532.5
OSCP1


organic solute carrier partner 1


chr16_+_28986134 0.129 ENST00000352260.7
SPNS1
spinster homolog 1 (Drosophila)
chr11_-_115375107 0.128 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1





cell adhesion molecule 1





chr2_+_45168875 0.128 ENST00000260653.3
SIX3
SIX homeobox 3
chr18_+_32398326 0.128 ENST00000269192.7
ENST00000591182.1
ENST00000597674.1
ENST00000556414.3
DTNA



dystrobrevin, alpha



chr11_-_61129723 0.127 ENST00000537680.1
ENST00000426130.2
ENST00000294072.4
CYB561A3


cytochrome b561 family, member A3


chr1_-_204380919 0.127 ENST00000367188.4
PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr7_+_99699179 0.127 ENST00000438383.1
ENST00000429084.1
ENST00000359593.4
ENST00000439416.1
AP4M1



adaptor-related protein complex 4, mu 1 subunit



chr16_+_57728701 0.126 ENST00000569375.1
ENST00000360716.3
ENST00000569167.1
ENST00000394337.4
ENST00000563126.1
ENST00000336825.8
CCDC135





coiled-coil domain containing 135





chr21_+_45719921 0.126 ENST00000349048.4
PFKL
phosphofructokinase, liver
chr1_-_201123546 0.126 ENST00000435310.1
ENST00000485839.2
ENST00000367330.1
TMEM9


transmembrane protein 9


chr1_-_201123586 0.126 ENST00000414605.2
ENST00000367334.5
ENST00000367332.1
TMEM9


transmembrane protein 9


chr11_-_119252425 0.126 ENST00000260187.2
USP2
ubiquitin specific peptidase 2
chr17_+_26662679 0.125 ENST00000578158.1
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr11_-_119252359 0.124 ENST00000455332.2
USP2
ubiquitin specific peptidase 2
chr15_+_76016293 0.124 ENST00000332145.2
ODF3L1
outer dense fiber of sperm tails 3-like 1
chr18_+_32397918 0.123 ENST00000590727.1
ENST00000601125.1
DTNA

dystrobrevin, alpha

chr16_+_30080857 0.123 ENST00000565355.1
ALDOA
aldolase A, fructose-bisphosphate
chr1_-_63988846 0.123 ENST00000283568.8
ENST00000371092.3
ENST00000271002.10
ITGB3BP


integrin beta 3 binding protein (beta3-endonexin)


chr19_-_55791540 0.122 ENST00000433386.2
HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr9_-_140009130 0.120 ENST00000497375.1
ENST00000371579.2
DPP7

dipeptidyl-peptidase 7

chr17_+_6554971 0.118 ENST00000391428.2
C17orf100
chromosome 17 open reading frame 100
chr6_-_32119877 0.117 ENST00000375152.2
PRRT1
proline-rich transmembrane protein 1
chr16_+_57662419 0.117 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
GPR56






G protein-coupled receptor 56






chr7_+_76751926 0.117 ENST00000285871.4
ENST00000431197.1
CCDC146

coiled-coil domain containing 146

chr11_+_537494 0.117 ENST00000270115.7
LRRC56
leucine rich repeat containing 56
chr14_+_77787227 0.117 ENST00000216465.5
ENST00000361389.4
ENST00000554279.1
ENST00000557639.1
ENST00000349555.3
ENST00000556627.1
ENST00000557053.1
GSTZ1






glutathione S-transferase zeta 1






chr6_+_42896865 0.116 ENST00000372836.4
ENST00000394142.3
CNPY3

canopy FGF signaling regulator 3

chr2_+_170335924 0.116 ENST00000554017.1
ENST00000392663.2
ENST00000513963.1
BBS5

RP11-724O16.1
Bardet-Biedl syndrome 5

Bardet-Biedl syndrome 5 protein; Uncharacterized protein
chr17_-_60885645 0.115 ENST00000544856.2
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr3_-_196045127 0.115 ENST00000325318.5
TCTEX1D2
Tctex1 domain containing 2
chr1_-_16563641 0.114 ENST00000375599.3
RSG1
REM2 and RAB-like small GTPase 1
chr7_+_2599056 0.114 ENST00000325979.7
ENST00000423395.1
IQCE

IQ motif containing E

chr17_+_4736627 0.113 ENST00000355280.6
ENST00000347992.7
MINK1

misshapen-like kinase 1

chr7_+_99699280 0.113 ENST00000421755.1
AP4M1
adaptor-related protein complex 4, mu 1 subunit
chr19_-_40324767 0.113 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
DYRK1B



dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B



chr14_+_74486043 0.112 ENST00000464394.1
ENST00000394009.3
CCDC176

coiled-coil domain containing 176

chr9_+_131084815 0.112 ENST00000300452.3
ENST00000609948.1
COQ4

coenzyme Q4

chr2_+_37458904 0.112 ENST00000416653.1
NDUFAF7
NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
chr17_+_78388959 0.111 ENST00000518137.1
ENST00000520367.1
ENST00000523999.1
ENST00000323854.5
ENST00000522751.1
ENDOV




endonuclease V




chr6_+_30848740 0.110 ENST00000505534.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr22_+_31892261 0.110 ENST00000432498.1
ENST00000540643.1
ENST00000443326.1
ENST00000414585.1
SFI1



Sfi1 homolog, spindle assembly associated (yeast)



chr1_+_111991474 0.109 ENST00000369722.3
ATP5F1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
chr2_-_220083671 0.108 ENST00000439002.2
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr19_-_50370799 0.108 ENST00000600910.1
ENST00000322344.3
ENST00000600573.1
PNKP


polynucleotide kinase 3'-phosphatase


chr11_-_61129335 0.108 ENST00000545361.1
ENST00000539128.1
ENST00000546151.1
ENST00000447532.2
CYB561A3



cytochrome b561 family, member A3



chr2_-_220083692 0.108 ENST00000265316.3
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr17_+_72199721 0.107 ENST00000439590.2
ENST00000311111.6
ENST00000584577.1
ENST00000534490.1
ENST00000528433.2
ENST00000533498.1
RPL38





ribosomal protein L38





chr11_-_75379479 0.107 ENST00000434603.2
MAP6
microtubule-associated protein 6
chr19_-_40950182 0.107 ENST00000596456.1
SERTAD3
SERTA domain containing 3
chr14_-_102829051 0.106 ENST00000536961.2
ENST00000541568.2
ENST00000216756.6
CINP


cyclin-dependent kinase 2 interacting protein


chr11_+_7041677 0.105 ENST00000299481.4
NLRP14
NLR family, pyrin domain containing 14
chrX_+_135251835 0.104 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr2_+_27193480 0.104 ENST00000233121.2
ENST00000405074.3
MAPRE3

microtubule-associated protein, RP/EB family, member 3

chr7_+_100273736 0.104 ENST00000412215.1
ENST00000393924.1
GNB2

guanine nucleotide binding protein (G protein), beta polypeptide 2

chr13_-_114843416 0.103 ENST00000389544.4
RASA3
RAS p21 protein activator 3
chr11_-_8832182 0.103 ENST00000527510.1
ENST00000528527.1
ENST00000528523.1
ENST00000313726.6
ST5



suppression of tumorigenicity 5



chr3_+_49027771 0.103 ENST00000475629.1
ENST00000444213.1
P4HTM

prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.1 0.8 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.3 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 0.8 GO:0044375 regulation of peroxisome size(GO:0044375)
0.1 0.3 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.6 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.3 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.3 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 0.3 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.3 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.1 0.2 GO:0099541 retrograde trans-synaptic signaling(GO:0098917) trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.1 0.2 GO:0090340 positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of pancreatic juice secretion(GO:0090187) positive regulation of secretion of lysosomal enzymes(GO:0090340)
0.1 0.2 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 0.2 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.5 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.1 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.3 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.2 GO:0098502 DNA dephosphorylation(GO:0098502)
0.0 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.2 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.1 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.2 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.2 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.0 0.3 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:1904448 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of dopamine secretion(GO:0033602) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.0 0.1 GO:0060298 regulation of vascular permeability involved in acute inflammatory response(GO:0002528) positive regulation of sarcomere organization(GO:0060298)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.2 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.0 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.2 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) protein O-linked glycosylation via serine(GO:0018242)
0.0 0.6 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.4 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 1.0 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.1 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.6 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.1 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.2 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.2 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.0 GO:2000625 regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.0 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.0 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.0 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.2 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.0 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.0 0.0 GO:0061009 common bile duct development(GO:0061009)
0.0 0.0 GO:0006174 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.0 0.2 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.2 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0070939 Dsl1p complex(GO:0070939)
0.1 0.2 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 0.2 GO:1990716 axonemal central apparatus(GO:1990716)
0.1 0.2 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.3 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.0 0.4 GO:0034464 BBSome(GO:0034464)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.5 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.9 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.8 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.0 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0033010 paranodal junction(GO:0033010)
0.0 0.1 GO:0035686 sperm fibrous sheath(GO:0035686)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.1 0.7 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.3 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.1 0.3 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.1 0.3 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 0.2 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 0.2 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.1 0.3 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.2 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.3 GO:0035473 lipase binding(GO:0035473)
0.0 0.3 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.1 GO:0052856 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.0 0.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0002046 opsin binding(GO:0002046)
0.0 0.2 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
0.0 0.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.2 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.1 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.1 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.2 GO:0005119 smoothened binding(GO:0005119)
0.0 0.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0050816 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.0 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.0 GO:0070984 SET domain binding(GO:0070984)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.3 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.4 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.6 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse