Motif ID: PROX1

Z-value: 0.420


Transcription factors associated with PROX1:

Gene SymbolEntrez IDGene Name
PROX1 ENSG00000117707.11 PROX1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PROX1hg19_v2_chr1_+_214161272_214161322-0.684.5e-02Click!


Activity profile for motif PROX1.

activity profile for motif PROX1


Sorted Z-values histogram for motif PROX1

Sorted Z-values for motif PROX1



Network of associatons between targets according to the STRING database.



First level regulatory network of PROX1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_152486108 0.542 ENST00000356661.5
MAGEA1
melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
chr7_-_138348969 0.503 ENST00000436657.1
SVOPL
SVOP-like
chr18_-_21562500 0.495 ENST00000582300.2
RP11-403A21.1
RP11-403A21.1
chr12_-_122296755 0.474 ENST00000289004.4
HPD
4-hydroxyphenylpyruvate dioxygenase
chrX_+_57618269 0.409 ENST00000374888.1
ZXDB
zinc finger, X-linked, duplicated B
chr18_+_33767473 0.370 ENST00000261326.5
MOCOS
molybdenum cofactor sulfurase
chr3_+_136676707 0.292 ENST00000329582.4
IL20RB
interleukin 20 receptor beta
chr1_+_70876926 0.273 ENST00000370938.3
ENST00000346806.2
CTH

cystathionase (cystathionine gamma-lyase)

chr1_+_70876891 0.254 ENST00000411986.2
CTH
cystathionase (cystathionine gamma-lyase)
chr11_+_93394805 0.246 ENST00000325212.6
ENST00000411936.1
ENST00000344196.4
KIAA1731


KIAA1731


chr1_-_22222764 0.221 ENST00000439717.2
ENST00000412328.1
HSPG2

heparan sulfate proteoglycan 2

chr1_-_15850676 0.219 ENST00000440484.1
ENST00000333868.5
CASP9

caspase 9, apoptosis-related cysteine peptidase

chr1_+_241695670 0.212 ENST00000366557.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr17_+_16593539 0.212 ENST00000340621.5
ENST00000399273.1
ENST00000443444.2
ENST00000360524.8
ENST00000456009.1
CCDC144A




coiled-coil domain containing 144A




chr11_-_83435965 0.205 ENST00000434967.1
ENST00000530800.1
DLG2

discs, large homolog 2 (Drosophila)

chr4_+_128886584 0.198 ENST00000513371.1
C4orf29
chromosome 4 open reading frame 29
chr17_-_38074859 0.197 ENST00000520542.1
ENST00000418519.1
ENST00000394179.1
GSDMB


gasdermin B


chr1_-_15850839 0.196 ENST00000348549.5
ENST00000546424.1
CASP9

caspase 9, apoptosis-related cysteine peptidase

chr1_+_241695424 0.195 ENST00000366558.3
ENST00000366559.4
KMO

kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)

chr11_-_83436446 0.195 ENST00000529399.1
DLG2
discs, large homolog 2 (Drosophila)
chr3_-_96337000 0.194 ENST00000600213.2
MTRNR2L12
MT-RNR2-like 12 (pseudogene)
chr5_-_22853429 0.177 ENST00000504376.2
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr10_-_14920599 0.167 ENST00000609399.1
RP11-398C13.6
RP11-398C13.6
chr7_+_66093851 0.166 ENST00000275532.3
KCTD7
potassium channel tetramerization domain containing 7
chr11_-_27384737 0.164 ENST00000317945.6
CCDC34
coiled-coil domain containing 34
chr7_-_102257139 0.158 ENST00000521076.1
ENST00000462172.1
ENST00000522801.1
ENST00000449970.2
ENST00000262940.7
RASA4




RAS p21 protein activator 4




chr11_+_6518503 0.157 ENST00000496802.1
ENST00000254579.6
ENST00000354685.3
DNHD1


dynein heavy chain domain 1


chr18_+_32073253 0.152 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
DTNA


dystrobrevin, alpha


chr4_-_169931393 0.137 ENST00000504480.1
ENST00000306193.3
CBR4

carbonyl reductase 4

chr12_-_117628333 0.127 ENST00000427718.2
FBXO21
F-box protein 21
chr12_+_49740700 0.126 ENST00000549441.2
ENST00000395069.3
DNAJC22

DnaJ (Hsp40) homolog, subfamily C, member 22

chr1_+_104068312 0.122 ENST00000524631.1
ENST00000531883.1
ENST00000533099.1
ENST00000527062.1
RNPC3



RNA-binding region (RNP1, RRM) containing 3



chr2_-_98280383 0.122 ENST00000289228.5
ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr12_-_117628253 0.121 ENST00000330622.5
FBXO21
F-box protein 21
chr16_-_10674528 0.120 ENST00000359543.3
EMP2
epithelial membrane protein 2
chr4_-_140477353 0.119 ENST00000406354.1
ENST00000506866.2
SETD7

SET domain containing (lysine methyltransferase) 7

chr22_-_39640756 0.117 ENST00000331163.6
PDGFB
platelet-derived growth factor beta polypeptide
chr21_-_34863693 0.116 ENST00000314399.3
DNAJC28
DnaJ (Hsp40) homolog, subfamily C, member 28
chr22_-_45559642 0.114 ENST00000426282.2
CTA-217C2.1
CTA-217C2.1
chr6_+_111580508 0.113 ENST00000368847.4
KIAA1919
KIAA1919
chr6_-_134495992 0.113 ENST00000475719.2
ENST00000367857.5
ENST00000237305.7
SGK1


serum/glucocorticoid regulated kinase 1


chr7_+_66093908 0.112 ENST00000443322.1
ENST00000449064.1
KCTD7

potassium channel tetramerization domain containing 7

chr12_-_51418549 0.111 ENST00000548150.1
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr4_+_128886532 0.110 ENST00000444616.1
ENST00000388795.5
C4orf29

chromosome 4 open reading frame 29

chr12_+_72079842 0.104 ENST00000266673.5
ENST00000550524.1
TMEM19

transmembrane protein 19

chr1_+_246729724 0.103 ENST00000366513.4
ENST00000366512.3
CNST

consortin, connexin sorting protein

chr6_-_90529418 0.103 ENST00000439638.1
ENST00000369393.3
ENST00000428876.1
MDN1


MDN1, midasin homolog (yeast)


chr12_-_122240792 0.099 ENST00000541657.1
ENST00000545885.1
ENST00000542933.1
ENST00000428029.2
ENST00000541694.1
ENST00000536662.1
ENST00000535643.1
RHOF
AC084018.1





ras homolog family member F (in filopodia)
AC084018.1





chr9_+_133986782 0.096 ENST00000372301.2
AIF1L
allograft inflammatory factor 1-like
chr18_-_2571210 0.095 ENST00000577166.1
METTL4
methyltransferase like 4
chr1_+_104068562 0.095 ENST00000423855.2
RNPC3
RNA-binding region (RNP1, RRM) containing 3
chr10_+_134258649 0.094 ENST00000392630.3
ENST00000321248.2
C10orf91

chromosome 10 open reading frame 91

chr10_+_71075552 0.094 ENST00000298649.3
HK1
hexokinase 1
chr1_-_204380919 0.093 ENST00000367188.4
PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr8_+_91013577 0.092 ENST00000220764.2
DECR1
2,4-dienoyl CoA reductase 1, mitochondrial
chr16_-_22012419 0.092 ENST00000537222.2
ENST00000424898.2
ENST00000286143.6
PDZD9


PDZ domain containing 9


chr17_+_66539369 0.090 ENST00000600820.1
AC079210.1
Uncharacterized protein; cDNA FLJ45097 fis, clone BRAWH3031054
chr17_-_7307358 0.088 ENST00000535512.1
ENST00000576017.1
ENST00000302422.3
TMEM256-PLSCR3
TMEM256

TMEM256-PLSCR3 readthrough (NMD candidate)
transmembrane protein 256

chr17_-_48546232 0.086 ENST00000258969.4
CHAD
chondroadherin
chr14_-_35183755 0.086 ENST00000555765.1
CFL2
cofilin 2 (muscle)
chr3_-_33138592 0.085 ENST00000415454.1
GLB1
galactosidase, beta 1
chr9_-_80437915 0.083 ENST00000397476.3
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr10_+_71075516 0.083 ENST00000436817.1
HK1
hexokinase 1
chr14_+_24563262 0.081 ENST00000559250.1
ENST00000216780.4
ENST00000560736.1
ENST00000396973.4
ENST00000559837.1
PCK2




phosphoenolpyruvate carboxykinase 2 (mitochondrial)




chr17_+_41994576 0.079 ENST00000588043.2
FAM215A
family with sequence similarity 215, member A (non-protein coding)
chr3_-_197025447 0.077 ENST00000346964.2
ENST00000357674.4
ENST00000314062.3
ENST00000448528.2
ENST00000419553.1
DLG1




discs, large homolog 1 (Drosophila)




chr16_+_31724552 0.077 ENST00000539915.1
ENST00000316491.9
ENST00000399681.3
ENST00000398696.3
ENST00000534369.1
ZNF720




zinc finger protein 720




chr2_-_200335983 0.076 ENST00000457245.1
SATB2
SATB homeobox 2
chr3_-_197024965 0.076 ENST00000392382.2
DLG1
discs, large homolog 1 (Drosophila)
chr5_-_132113083 0.075 ENST00000296873.7
SEPT8
septin 8
chr11_+_28131821 0.074 ENST00000379199.2
ENST00000303459.6
METTL15

methyltransferase like 15

chr22_+_24990746 0.071 ENST00000456869.1
ENST00000411974.1
GGT1

gamma-glutamyltransferase 1

chr14_-_23426231 0.071 ENST00000556915.1
HAUS4
HAUS augmin-like complex, subunit 4
chr10_+_30722866 0.070 ENST00000263056.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr9_+_72873837 0.070 ENST00000361138.5
SMC5
structural maintenance of chromosomes 5
chr14_-_36645674 0.070 ENST00000556013.2
PTCSC3
papillary thyroid carcinoma susceptibility candidate 3 (non-protein coding)
chr14_-_105420241 0.069 ENST00000557457.1
AHNAK2
AHNAK nucleoprotein 2
chr3_-_33138624 0.068 ENST00000445488.2
ENST00000307377.8
ENST00000440656.1
ENST00000436768.1
ENST00000307363.5
GLB1




galactosidase, beta 1




chr14_+_37641012 0.066 ENST00000556667.1
SLC25A21-AS1
SLC25A21 antisense RNA 1
chr1_+_154966058 0.065 ENST00000392487.1
LENEP
lens epithelial protein
chr4_+_2819883 0.064 ENST00000511747.1
ENST00000503393.2
SH3BP2

SH3-domain binding protein 2

chr14_-_23426322 0.063 ENST00000555367.1
HAUS4
HAUS augmin-like complex, subunit 4
chr19_-_9546227 0.063 ENST00000361451.2
ENST00000361151.1
ZNF266

zinc finger protein 266

chr19_-_9546177 0.063 ENST00000592292.1
ENST00000588221.1
ZNF266

zinc finger protein 266

chr7_+_99775520 0.063 ENST00000317296.5
ENST00000422690.1
ENST00000439782.1
STAG3


stromal antigen 3


chr1_+_171454639 0.062 ENST00000392078.3
ENST00000426496.2
PRRC2C

proline-rich coiled-coil 2C

chr12_-_11091862 0.061 ENST00000537503.1
TAS2R14
taste receptor, type 2, member 14
chr5_-_132113036 0.061 ENST00000378706.1
SEPT8
septin 8
chr9_+_132096166 0.060 ENST00000436710.1
RP11-65J3.1
RP11-65J3.1
chr7_+_64254766 0.059 ENST00000307355.7
ENST00000359735.3
ZNF138

zinc finger protein 138

chr10_-_50970382 0.059 ENST00000419399.1
ENST00000432695.1
OGDHL

oxoglutarate dehydrogenase-like

chr1_+_93297582 0.058 ENST00000370321.3
RPL5
ribosomal protein L5
chr14_-_23426270 0.057 ENST00000557591.1
ENST00000397409.4
ENST00000490506.1
ENST00000554406.1
HAUS4



HAUS augmin-like complex, subunit 4



chr14_-_23426337 0.057 ENST00000342454.8
ENST00000555986.1
ENST00000541587.1
ENST00000554516.1
ENST00000347758.2
ENST00000206474.7
ENST00000555040.1
HAUS4






HAUS augmin-like complex, subunit 4






chr11_-_82997013 0.057 ENST00000529073.1
ENST00000529611.1
CCDC90B

coiled-coil domain containing 90B

chr17_-_48546324 0.057 ENST00000508540.1
CHAD
chondroadherin
chr7_-_12443501 0.057 ENST00000275358.3
VWDE
von Willebrand factor D and EGF domains
chr10_+_104474353 0.057 ENST00000602647.1
ENST00000602439.1
ENST00000602764.1
SFXN2


sideroflexin 2


chr10_-_123357598 0.056 ENST00000358487.5
ENST00000369058.3
ENST00000369060.4
ENST00000359354.2
FGFR2



fibroblast growth factor receptor 2



chr1_+_93297622 0.055 ENST00000315741.5
RPL5
ribosomal protein L5
chr11_-_73882029 0.055 ENST00000539061.1
C2CD3
C2 calcium-dependent domain containing 3
chr3_-_33138286 0.055 ENST00000399402.3
ENST00000416695.2
ENST00000342462.4
GLB1
TMPPE

galactosidase, beta 1
transmembrane protein with metallophosphoesterase domain

chr19_+_45754505 0.055 ENST00000262891.4
ENST00000300843.4
MARK4

MAP/microtubule affinity-regulating kinase 4

chr10_+_30723045 0.055 ENST00000542547.1
ENST00000415139.1
MAP3K8

mitogen-activated protein kinase kinase kinase 8

chr16_+_50300427 0.052 ENST00000394697.2
ENST00000566433.2
ENST00000538642.1
ADCY7


adenylate cyclase 7


chr6_-_28226984 0.052 ENST00000423974.2
ZKSCAN4
zinc finger with KRAB and SCAN domains 4
chr7_-_102158157 0.052 ENST00000541662.1
ENST00000306682.6
ENST00000465829.1
RASA4B


RAS p21 protein activator 4B


chr1_-_246729544 0.051 ENST00000544618.1
ENST00000366514.4
TFB2M

transcription factor B2, mitochondrial

chr1_+_154909803 0.051 ENST00000604546.1
RP11-307C12.13
RP11-307C12.13
chr18_+_32073839 0.051 ENST00000590412.1
DTNA
dystrobrevin, alpha
chr22_-_45559540 0.049 ENST00000432502.1
CTA-217C2.1
CTA-217C2.1
chr6_-_72129806 0.049 ENST00000413945.1
ENST00000602878.1
ENST00000436803.1
ENST00000421704.1
ENST00000441570.1
LINC00472




long intergenic non-protein coding RNA 472




chr4_-_170948361 0.048 ENST00000393702.3
MFAP3L
microfibrillar-associated protein 3-like
chr7_-_25164969 0.048 ENST00000305786.2
CYCS
cytochrome c, somatic
chr16_+_22518495 0.047 ENST00000541154.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chr8_+_104310661 0.047 ENST00000522566.1
FZD6
frizzled family receptor 6
chr3_-_137834436 0.047 ENST00000327532.2
ENST00000467030.1
DZIP1L

DAZ interacting zinc finger protein 1-like

chr8_+_70476088 0.046 ENST00000525999.1
SULF1
sulfatase 1
chr15_+_85523671 0.045 ENST00000310298.4
ENST00000557957.1
PDE8A

phosphodiesterase 8A

chr12_-_58240470 0.043 ENST00000548823.1
ENST00000398073.2
CTDSP2

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2

chr11_-_61062762 0.042 ENST00000335613.5
VWCE
von Willebrand factor C and EGF domains
chr3_-_130745571 0.042 ENST00000514044.1
ENST00000264992.3
ASTE1

asteroid homolog 1 (Drosophila)

chr3_-_48723268 0.041 ENST00000439518.1
ENST00000416649.2
ENST00000341520.4
ENST00000294129.2
NCKIPSD



NCK interacting protein with SH3 domain



chr5_-_132113063 0.041 ENST00000378719.2
SEPT8
septin 8
chr7_-_25164868 0.040 ENST00000409409.1
ENST00000409764.1
ENST00000413447.1
CYCS


cytochrome c, somatic


chr7_+_128864848 0.040 ENST00000325006.3
ENST00000446544.2
AHCYL2

adenosylhomocysteinase-like 2

chr10_-_43633747 0.040 ENST00000609407.1
RP11-351D16.3
RP11-351D16.3
chr16_+_28857916 0.039 ENST00000563591.1
SH2B1
SH2B adaptor protein 1
chr5_-_180688105 0.039 ENST00000327767.4
TRIM52
tripartite motif containing 52
chr7_+_47834880 0.039 ENST00000258776.4
C7orf69
chromosome 7 open reading frame 69
chr5_-_72861175 0.038 ENST00000504641.1
ANKRA2
ankyrin repeat, family A (RFXANK-like), 2
chr11_-_82997371 0.038 ENST00000525503.1
CCDC90B
coiled-coil domain containing 90B
chr19_+_1354930 0.038 ENST00000591337.1
MUM1
melanoma associated antigen (mutated) 1
chr1_+_95975672 0.037 ENST00000440116.2
ENST00000456933.1
RP11-286B14.1

RP11-286B14.1

chr13_+_113699029 0.037 ENST00000423251.1
MCF2L
MCF.2 cell line derived transforming sequence-like
chr5_+_131892603 0.037 ENST00000378823.3
ENST00000265335.6
RAD50

RAD50 homolog (S. cerevisiae)

chr22_+_18121562 0.035 ENST00000355028.3
BCL2L13
BCL2-like 13 (apoptosis facilitator)
chr3_+_49941420 0.035 ENST00000419183.1
CTD-2330K9.3
Uncharacterized protein
chr16_-_18801643 0.035 ENST00000322989.4
ENST00000563390.1
RPS15A

ribosomal protein S15a

chr15_-_91537723 0.035 ENST00000394249.3
ENST00000559811.1
ENST00000442656.2
ENST00000557905.1
ENST00000361919.3
PRC1




protein regulator of cytokinesis 1




chr7_+_64254793 0.035 ENST00000494380.1
ENST00000440155.2
ENST00000440598.1
ENST00000437743.1
ZNF138



zinc finger protein 138



chr7_+_1609765 0.034 ENST00000437964.1
ENST00000533935.1
ENST00000532358.1
ENST00000524978.1
PSMG3-AS1



PSMG3 antisense RNA 1 (head to head)



chr11_-_73882249 0.033 ENST00000535954.1
C2CD3
C2 calcium-dependent domain containing 3
chr1_+_171454659 0.033 ENST00000367742.3
ENST00000338920.4
PRRC2C

proline-rich coiled-coil 2C

chr11_+_117947724 0.033 ENST00000534111.1
TMPRSS4
transmembrane protease, serine 4
chr8_-_135652051 0.033 ENST00000522257.1
ZFAT
zinc finger and AT hook domain containing
chr11_-_73882057 0.033 ENST00000334126.7
ENST00000313663.7
C2CD3

C2 calcium-dependent domain containing 3

chr19_-_46234119 0.032 ENST00000317683.3
FBXO46
F-box protein 46
chr11_-_4719072 0.032 ENST00000396950.3
ENST00000532598.1
OR51E2

olfactory receptor, family 51, subfamily E, member 2

chr19_-_44809121 0.032 ENST00000591609.1
ENST00000589799.1
ENST00000291182.4
ENST00000589248.1
ZNF235



zinc finger protein 235



chr16_+_58059470 0.032 ENST00000219271.3
MMP15
matrix metallopeptidase 15 (membrane-inserted)
chr7_+_100209979 0.032 ENST00000493970.1
ENST00000379527.2
MOSPD3

motile sperm domain containing 3

chr10_-_50970322 0.032 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chr1_-_182369751 0.031 ENST00000367565.1
TEDDM1
transmembrane epididymal protein 1
chr19_+_23945768 0.031 ENST00000486528.1
ENST00000496398.1
RPSAP58

ribosomal protein SA pseudogene 58

chrX_+_117861535 0.030 ENST00000371666.3
ENST00000371642.1
IL13RA1

interleukin 13 receptor, alpha 1

chr14_-_54425475 0.030 ENST00000559642.1
BMP4
bone morphogenetic protein 4
chr1_-_44497024 0.030 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
SLC6A9


solute carrier family 6 (neurotransmitter transporter, glycine), member 9


chr11_+_111749650 0.030 ENST00000528125.1
C11orf1
chromosome 11 open reading frame 1
chr10_+_32735177 0.030 ENST00000545067.1
CCDC7
coiled-coil domain containing 7
chr4_+_128886424 0.029 ENST00000398965.1
C4orf29
chromosome 4 open reading frame 29
chr11_+_61522844 0.028 ENST00000265460.5
MYRF
myelin regulatory factor
chr3_-_25915189 0.027 ENST00000451284.1
LINC00692
long intergenic non-protein coding RNA 692
chr11_+_1874200 0.027 ENST00000311604.3
LSP1
lymphocyte-specific protein 1
chr7_-_91509986 0.026 ENST00000456229.1
ENST00000442961.1
ENST00000406735.2
ENST00000419292.1
ENST00000351870.3
MTERF




mitochondrial transcription termination factor




chr2_-_42588338 0.026 ENST00000234301.2
COX7A2L
cytochrome c oxidase subunit VIIa polypeptide 2 like
chr15_-_76304731 0.026 ENST00000394907.3
NRG4
neuregulin 4
chr9_-_86571628 0.026 ENST00000376344.3
C9orf64
chromosome 9 open reading frame 64
chr14_-_31676964 0.026 ENST00000553700.1
HECTD1
HECT domain containing E3 ubiquitin protein ligase 1
chr6_-_86303833 0.025 ENST00000505648.1
SNX14
sorting nexin 14
chr22_+_18121356 0.025 ENST00000317582.5
ENST00000543133.1
ENST00000538149.1
ENST00000337612.5
ENST00000493680.1
BCL2L13




BCL2-like 13 (apoptosis facilitator)




chr16_+_85832146 0.025 ENST00000565078.1
COX4I1
cytochrome c oxidase subunit IV isoform 1
chr17_+_21730180 0.025 ENST00000584398.1
UBBP4
ubiquitin B pseudogene 4
chr9_-_127533519 0.024 ENST00000487099.2
ENST00000344523.4
ENST00000373584.3
NR6A1


nuclear receptor subfamily 6, group A, member 1


chr11_-_46408107 0.024 ENST00000433765.2
CHRM4
cholinergic receptor, muscarinic 4
chr19_-_12267524 0.024 ENST00000455799.1
ENST00000355738.1
ENST00000439556.2
ENST00000542938.1
ZNF625



zinc finger protein 625



chr3_-_47950745 0.023 ENST00000429422.1
MAP4
microtubule-associated protein 4
chr6_+_28227063 0.023 ENST00000343684.3
NKAPL
NFKB activating protein-like
chr16_+_23194033 0.022 ENST00000300061.2
SCNN1G
sodium channel, non-voltage-gated 1, gamma subunit
chr11_+_111749942 0.022 ENST00000260276.3
C11orf1
chromosome 11 open reading frame 1
chr7_+_99724317 0.022 ENST00000398075.2
ENST00000421390.1
MBLAC1

metallo-beta-lactamase domain containing 1

chr20_-_61885826 0.022 ENST00000370316.3
NKAIN4
Na+/K+ transporting ATPase interacting 4
chr6_+_158957431 0.022 ENST00000367090.3
TMEM181
transmembrane protein 181
chr11_+_57308979 0.021 ENST00000457912.1
SMTNL1
smoothelin-like 1
chr7_+_100209725 0.021 ENST00000223054.4
MOSPD3
motile sperm domain containing 3
chr1_-_154178803 0.020 ENST00000368525.3
C1orf189
chromosome 1 open reading frame 189
chr10_-_94301107 0.020 ENST00000436178.1
IDE
insulin-degrading enzyme
chr6_+_144665237 0.020 ENST00000421035.2
UTRN
utrophin
chr11_+_64008525 0.019 ENST00000449942.2
FKBP2
FK506 binding protein 2, 13kDa
chr12_+_20522179 0.019 ENST00000359062.3
PDE3A
phosphodiesterase 3A, cGMP-inhibited
chr4_-_170947522 0.019 ENST00000361618.3
MFAP3L
microfibrillar-associated protein 3-like
chr5_+_64859066 0.019 ENST00000261308.5
ENST00000535264.1
ENST00000538977.1
PPWD1


peptidylprolyl isomerase domain and WD repeat containing 1


chr6_-_4079334 0.019 ENST00000492651.1
ENST00000498677.1
ENST00000274673.3
FAM217A


family with sequence similarity 217, member A


chr2_-_122262593 0.019 ENST00000418989.1
CLASP1
cytoplasmic linker associated protein 1
chr7_+_100210133 0.019 ENST00000393950.2
ENST00000424091.2
MOSPD3

motile sperm domain containing 3

chr21_-_16125773 0.018 ENST00000454128.2
AF127936.3
AF127936.3
chr2_+_17935383 0.018 ENST00000524465.1
ENST00000381254.2
ENST00000532257.1
GEN1


GEN1 Holliday junction 5' flap endonuclease


chr18_+_60190226 0.018 ENST00000269499.5
ZCCHC2
zinc finger, CCHC domain containing 2
chr18_-_2571437 0.018 ENST00000574676.1
ENST00000574538.1
ENST00000319888.6
METTL4


methyltransferase like 4


chr9_+_131266963 0.018 ENST00000309971.4
ENST00000372770.4
GLE1

GLE1 RNA export mediator


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.3 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.1 0.4 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.5 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.2 GO:0051413 response to cortisone(GO:0051413)
0.0 0.4 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.1 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0 0.1 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.0 0.0 GO:0000022 mitotic spindle elongation(GO:0000022)
0.0 0.1 GO:0072255 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.0 0.1 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.5 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.1 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.1 GO:0060648 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) mammary gland bud morphogenesis(GO:0060648) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.0 0.1 GO:0015692 lead ion transport(GO:0015692)
0.0 0.1 GO:0021997 neural plate axis specification(GO:0021997)
0.0 0.2 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.2 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.1 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.0 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.2 GO:0044597 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0 0.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:1903912 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.0 0.4 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.1 GO:0006116 NADH oxidation(GO:0006116)
0.0 0.1 GO:0070836 caveola assembly(GO:0070836)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0043293 apoptosome(GO:0043293)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.4 GO:0030151 molybdenum ion binding(GO:0030151)
0.1 0.2 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 0.2 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.5 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:0016936 galactoside binding(GO:0016936)
0.0 0.2 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.0 0.4 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.1 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
0.0 0.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.1 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.1 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.4 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.5 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism