Motif ID: PRDM4

Z-value: 0.325


Transcription factors associated with PRDM4:

Gene SymbolEntrez IDGene Name
PRDM4 ENSG00000110851.7 PRDM4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PRDM4hg19_v2_chr12_-_108154705_108154776-0.264.9e-01Click!


Activity profile for motif PRDM4.

activity profile for motif PRDM4


Sorted Z-values histogram for motif PRDM4

Sorted Z-values for motif PRDM4



Network of associatons between targets according to the STRING database.



First level regulatory network of PRDM4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_49371711 0.398 ENST00000355496.5
ENST00000263265.6
 PLEKHA4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

chr22_-_39636914 0.196 ENST00000381551.4
 PDGFB
platelet-derived growth factor beta polypeptide
chr14_+_105953246 0.172 ENST00000392531.3
 CRIP1
cysteine-rich protein 1 (intestinal)
chr14_+_105953204 0.171 ENST00000409393.2
 CRIP1
cysteine-rich protein 1 (intestinal)
chr17_+_42634844 0.157 ENST00000315323.3
 FZD2
frizzled family receptor 2
chr2_+_219264762 0.151 ENST00000452977.1
 CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr9_+_139560197 0.125 ENST00000371698.3
 EGFL7
EGF-like-domain, multiple 7
chr19_+_41117770 0.123 ENST00000601032.1
 LTBP4
latent transforming growth factor beta binding protein 4
chr2_+_219264466 0.117 ENST00000273062.2
 CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr14_-_24732738 0.116 ENST00000558074.1
ENST00000560226.1
 TGM1

transglutaminase 1

chr7_+_143078652 0.106 ENST00000354434.4
ENST00000449423.2
 ZYX

zyxin

chr19_-_11639931 0.104 ENST00000592312.1
ENST00000590480.1
ENST00000585318.1
ENST00000252440.7
ENST00000417981.2
ENST00000270517.7
 ECSIT





ECSIT signalling integrator





chr20_+_62697564 0.090 ENST00000458442.1
 TCEA2
transcription elongation factor A (SII), 2
chr7_+_143079000 0.089 ENST00000392910.2
 ZYX
zyxin
chr22_+_38864041 0.086 ENST00000216014.4
ENST00000409006.3
 KDELR3

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3

chr1_-_68516393 0.085 ENST00000395201.1
 DIRAS3
DIRAS family, GTP-binding RAS-like 3
chr19_-_11639910 0.085 ENST00000588998.1
ENST00000586149.1
 ECSIT

ECSIT signalling integrator

chr6_-_32160622 0.085 ENST00000487761.1
ENST00000375040.3
 GPSM3

G-protein signaling modulator 3

chr2_+_234296792 0.083 ENST00000409813.3
 DGKD
diacylglycerol kinase, delta 130kDa
chr12_-_58240470 0.075 ENST00000548823.1
ENST00000398073.2
 CTDSP2

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2

chr12_+_80838126 0.069 ENST00000266688.5
 PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr19_+_42724423 0.068 ENST00000301215.3
ENST00000597945.1
 ZNF526

zinc finger protein 526

chr1_+_27113963 0.064 ENST00000430292.1
 PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr15_+_74287035 0.061 ENST00000395132.2
ENST00000268059.6
ENST00000354026.6
ENST00000268058.3
ENST00000565898.1
ENST00000569477.1
ENST00000569965.1
ENST00000567543.1
ENST00000436891.3
ENST00000435786.2
ENST00000564428.1
ENST00000359928.4
 PML











promyelocytic leukemia











chr1_+_27114418 0.059 ENST00000078527.4
 PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr8_-_135652051 0.058 ENST00000522257.1
 ZFAT
zinc finger and AT hook domain containing
chr19_-_35264089 0.057 ENST00000588760.1
ENST00000329285.8
ENST00000587354.2
 ZNF599


zinc finger protein 599


chr1_-_43232649 0.055 ENST00000372526.2
ENST00000236040.4
ENST00000296388.5
ENST00000397054.3
 LEPRE1



leucine proline-enriched proteoglycan (leprecan) 1



chr2_-_179343268 0.051 ENST00000424785.2
 FKBP7
FK506 binding protein 7
chr14_-_74462922 0.048 ENST00000553284.1
 ENTPD5
ectonucleoside triphosphate diphosphohydrolase 5
chr11_+_47279504 0.047 ENST00000441012.2
ENST00000437276.1
ENST00000436029.1
ENST00000467728.1
ENST00000405853.3
 NR1H3




nuclear receptor subfamily 1, group H, member 3




chr17_-_9929581 0.046 ENST00000437099.2
ENST00000396115.2
 GAS7

growth arrest-specific 7

chr6_-_24721054 0.041 ENST00000378119.4
 C6orf62
chromosome 6 open reading frame 62
chr14_+_24025194 0.041 ENST00000404535.3
ENST00000288014.6
 THTPA

thiamine triphosphatase

chr14_+_24025345 0.040 ENST00000557630.1
 THTPA
thiamine triphosphatase
chr1_+_27114589 0.038 ENST00000431541.1
ENST00000449950.2
ENST00000374145.1
 PIGV


phosphatidylinositol glycan anchor biosynthesis, class V


chr2_-_179343226 0.037 ENST00000434643.2
 FKBP7
FK506 binding protein 7
chr5_-_34916871 0.036 ENST00000382038.2
 RAD1
RAD1 homolog (S. pombe)
chr16_+_88636789 0.034 ENST00000301011.5
ENST00000452588.2
 ZC3H18

zinc finger CCCH-type containing 18

chr11_-_67188642 0.033 ENST00000546202.1
ENST00000542876.1
 PPP1CA

protein phosphatase 1, catalytic subunit, alpha isozyme

chr5_-_78281623 0.031 ENST00000521117.1
 ARSB
arylsulfatase B
chr10_-_105677886 0.029 ENST00000224950.3
 OBFC1
oligonucleotide/oligosaccharide-binding fold containing 1
chr7_+_90893783 0.026 ENST00000287934.2
 FZD1
frizzled family receptor 1
chr10_+_88728189 0.025 ENST00000416348.1
 ADIRF
adipogenesis regulatory factor
chr6_-_8064567 0.020 ENST00000543936.1
ENST00000397457.2
 BLOC1S5

biogenesis of lysosomal organelles complex-1, subunit 5, muted

chr5_+_140261703 0.016 ENST00000409494.1
ENST00000289272.2
 PCDHA13

protocadherin alpha 13

chr20_+_61569463 0.016 ENST00000266069.3
 GID8
GID complex subunit 8
chr11_-_6913830 0.015 ENST00000299459.2
 OR2D2
olfactory receptor, family 2, subfamily D, member 2
chr4_+_667307 0.015 ENST00000506838.1
 MYL5
myosin, light chain 5, regulatory
chr17_+_7788104 0.015 ENST00000380358.4
 CHD3
chromodomain helicase DNA binding protein 3
chr20_+_30555805 0.014 ENST00000562532.2
 XKR7
XK, Kell blood group complex subunit-related family, member 7
chr1_+_55107449 0.013 ENST00000421030.2
ENST00000545244.1
ENST00000339553.5
ENST00000409996.1
ENST00000454855.2
 MROH7




maestro heat-like repeat family member 7




chr19_+_50180317 0.012 ENST00000534465.1
 PRMT1
protein arginine methyltransferase 1
chr1_+_6511651 0.010 ENST00000434576.1
 ESPN
espin
chr11_+_58910295 0.006 ENST00000420244.1
 FAM111A
family with sequence similarity 111, member A
chr8_+_94712752 0.005 ENST00000522324.1
ENST00000522803.1
ENST00000423990.2
 FAM92A1


family with sequence similarity 92, member A1


chrX_-_73072534 0.005 ENST00000429829.1
 XIST
X inactive specific transcript (non-protein coding)
chr16_+_88636875 0.004 ENST00000569435.1
 ZC3H18
zinc finger CCCH-type containing 18
chr3_+_148709128 0.003 ENST00000345003.4
ENST00000296048.6
ENST00000483267.1
 GYG1


glycogenin 1


chr3_+_16926441 0.003 ENST00000418129.2
ENST00000396755.2
 PLCL2

phospholipase C-like 2

chr12_+_15475331 0.002 ENST00000281171.4
 PTPRO
protein tyrosine phosphatase, receptor type, O
chr7_-_23571586 0.001 ENST00000538367.1
ENST00000392502.4
ENST00000297071.4
 TRA2A


transformer 2 alpha homolog (Drosophila)


chr20_+_58296265 0.001 ENST00000395636.2
ENST00000361300.4
 PHACTR3

phosphatase and actin regulator 3

chr7_-_38398721 0.000 ENST00000390346.2
 TRGV3
T cell receptor gamma variable 3
chr12_+_15475462 0.000 ENST00000543886.1
ENST00000348962.2
 PTPRO

protein tyrosine phosphatase, receptor type, O


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.2 GO:0072255 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.0 0.1 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.2 GO:0003150 muscular septum morphogenesis(GO:0003150)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0031501 mannosyltransferase complex(GO:0031501)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 0.1 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176) platelet-derived growth factor binding(GO:0048407)