Motif ID: PRDM14

Z-value: 0.159


Transcription factors associated with PRDM14:

Gene SymbolEntrez IDGene Name
PRDM14 ENSG00000147596.3 PRDM14

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PRDM14hg19_v2_chr8_-_70983506_709835620.618.1e-02Click!


Activity profile for motif PRDM14.

activity profile for motif PRDM14


Sorted Z-values histogram for motif PRDM14

Sorted Z-values for motif PRDM14



Network of associatons between targets according to the STRING database.



First level regulatory network of PRDM14

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_31845914 0.113 ENST00000373713.2
 FABP3
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr19_+_49838653 0.105 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
 CD37





CD37 molecule





chr14_+_21492331 0.085 ENST00000533984.1
ENST00000532213.2
 AL161668.5

AL161668.5

chr1_+_109102652 0.083 ENST00000370035.3
ENST00000405454.1
 FAM102B

family with sequence similarity 102, member B

chr5_+_32710736 0.083 ENST00000415685.2
 NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr8_+_101349823 0.081 ENST00000519566.1
 KB-1991G8.1
KB-1991G8.1
chr5_-_24645078 0.071 ENST00000264463.4
 CDH10
cadherin 10, type 2 (T2-cadherin)
chr5_+_32711419 0.059 ENST00000265074.8
 NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr11_+_62475130 0.057 ENST00000294117.5
 GNG3
guanine nucleotide binding protein (G protein), gamma 3
chr1_+_45274154 0.055 ENST00000450269.1
ENST00000453418.1
ENST00000409335.2
 BTBD19


BTB (POZ) domain containing 19


chr6_+_72926145 0.049 ENST00000425662.2
ENST00000453976.2
 RIMS1

regulating synaptic membrane exocytosis 1

chr7_-_30066233 0.042 ENST00000222803.5
 FKBP14
FK506 binding protein 14, 22 kDa
chr12_-_124456598 0.042 ENST00000539761.1
ENST00000539551.1
 CCDC92

coiled-coil domain containing 92

chr1_-_155006224 0.041 ENST00000368424.3
 DCST2
DC-STAMP domain containing 2
chr19_+_39109735 0.039 ENST00000593149.1
ENST00000248342.4
ENST00000538434.1
ENST00000588934.1
ENST00000545173.2
ENST00000589307.1
ENST00000586513.1
ENST00000591409.1
ENST00000592558.1
 EIF3K








eukaryotic translation initiation factor 3, subunit K








chr1_-_155006254 0.038 ENST00000295536.5
 DCST2
DC-STAMP domain containing 2
chr13_-_34250861 0.038 ENST00000445227.1
ENST00000454681.2
 RP11-141M1.3

RP11-141M1.3

chr7_-_124405681 0.033 ENST00000303921.2
 GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr13_-_52026730 0.032 ENST00000420668.2
 INTS6
integrator complex subunit 6
chr19_-_49314169 0.032 ENST00000597011.1
ENST00000601681.1
 BCAT2

branched chain amino-acid transaminase 2, mitochondrial

chr1_+_39796810 0.031 ENST00000289893.4
 MACF1
microtubule-actin crosslinking factor 1
chr19_-_6279932 0.031 ENST00000252674.7
 MLLT1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr17_-_17726907 0.027 ENST00000423161.3
 SREBF1
sterol regulatory element binding transcription factor 1
chr12_-_76742183 0.027 ENST00000393262.3
 BBS10
Bardet-Biedl syndrome 10
chr1_+_153963227 0.026 ENST00000368567.4
ENST00000392558.4
 RPS27

ribosomal protein S27

chr19_+_3572758 0.025 ENST00000416526.1
 HMG20B
high mobility group 20B
chr19_-_49314269 0.025 ENST00000545387.2
ENST00000316273.6
ENST00000402551.1
ENST00000598162.1
ENST00000599246.1
 BCAT2




branched chain amino-acid transaminase 2, mitochondrial




chr16_-_55866997 0.024 ENST00000360526.3
ENST00000361503.4
 CES1

carboxylesterase 1

chr1_+_27114589 0.024 ENST00000431541.1
ENST00000449950.2
ENST00000374145.1
 PIGV


phosphatidylinositol glycan anchor biosynthesis, class V


chr21_+_26934165 0.023 ENST00000456917.1
 MIR155HG
MIR155 host gene (non-protein coding)
chr2_+_113033164 0.023 ENST00000409871.1
ENST00000343936.4
 ZC3H6

zinc finger CCCH-type containing 6

chr20_-_3154162 0.023 ENST00000360342.3
 LZTS3
Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr4_+_81187753 0.023 ENST00000312465.7
ENST00000456523.3
 FGF5

fibroblast growth factor 5

chr1_+_27114418 0.023 ENST00000078527.4
 PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr15_+_69850521 0.022 ENST00000558781.1
 RP11-279F6.1
RP11-279F6.1
chr11_+_64879317 0.022 ENST00000526809.1
ENST00000279263.7
ENST00000524986.1
ENST00000534371.1
ENST00000540748.1
ENST00000525385.1
ENST00000345348.5
ENST00000531321.1
ENST00000529414.1
ENST00000526085.1
ENST00000530750.1
 TM7SF2










transmembrane 7 superfamily member 2










chr3_+_155838337 0.022 ENST00000490337.1
ENST00000389636.5
 KCNAB1

potassium voltage-gated channel, shaker-related subfamily, beta member 1

chr11_-_62474803 0.020 ENST00000533982.1
ENST00000360796.5
 BSCL2

Berardinelli-Seip congenital lipodystrophy 2 (seipin)

chr2_-_192711968 0.018 ENST00000304141.4
 SDPR
serum deprivation response
chr17_+_41924536 0.018 ENST00000317310.4
 CD300LG
CD300 molecule-like family member g
chr19_+_38880252 0.017 ENST00000586301.1
 SPRED3
sprouty-related, EVH1 domain containing 3
chr1_+_27668505 0.016 ENST00000318074.5
 SYTL1
synaptotagmin-like 1
chr2_-_208030886 0.016 ENST00000426163.1
 KLF7
Kruppel-like factor 7 (ubiquitous)
chrX_+_51636629 0.016 ENST00000375722.1
ENST00000326587.7
ENST00000375695.2
 MAGED1


melanoma antigen family D, 1


chr2_-_228244013 0.016 ENST00000304568.3
 TM4SF20
transmembrane 4 L six family member 20
chr9_+_132597722 0.015 ENST00000372429.3
ENST00000315480.4
ENST00000358355.1
 USP20


ubiquitin specific peptidase 20


chr2_-_37193606 0.014 ENST00000379213.2
ENST00000263918.4
 STRN

striatin, calmodulin binding protein

chr4_+_141677577 0.013 ENST00000609937.1
 RP11-102N12.3
RP11-102N12.3
chr3_-_143567262 0.013 ENST00000474151.1
ENST00000316549.6
 SLC9A9

solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9

chr14_-_21492113 0.012 ENST00000554094.1
 NDRG2
NDRG family member 2
chr7_-_44580861 0.012 ENST00000546276.1
ENST00000289547.4
ENST00000381160.3
ENST00000423141.1
 NPC1L1



NPC1-like 1



chr3_-_114477962 0.011 ENST00000471418.1
 ZBTB20
zinc finger and BTB domain containing 20
chr14_-_54425475 0.010 ENST00000559642.1
 BMP4
bone morphogenetic protein 4
chr2_-_145277882 0.010 ENST00000465070.1
ENST00000444559.1
 ZEB2

zinc finger E-box binding homeobox 2

chr9_+_132099158 0.010 ENST00000444125.1
 RP11-65J3.1
RP11-65J3.1
chr11_+_85566422 0.010 ENST00000342404.3
 CCDC83
coiled-coil domain containing 83
chr19_-_53757941 0.009 ENST00000594517.1
ENST00000601413.1
ENST00000594681.1
 ZNF677


zinc finger protein 677


chr12_+_49760639 0.009 ENST00000549538.1
ENST00000548654.1
ENST00000550643.1
ENST00000548710.1
ENST00000549179.1
ENST00000548377.1
 SPATS2





spermatogenesis associated, serine-rich 2





chr15_-_45694380 0.009 ENST00000561148.1
 GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr8_+_110346546 0.008 ENST00000521662.1
ENST00000521688.1
ENST00000520147.1
 ENY2


enhancer of yellow 2 homolog (Drosophila)


chr2_-_208030647 0.008 ENST00000309446.6
 KLF7
Kruppel-like factor 7 (ubiquitous)
chr1_+_65730385 0.008 ENST00000263441.7
ENST00000395325.3
 DNAJC6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr7_-_140714739 0.007 ENST00000467334.1
ENST00000324787.5
 MRPS33

mitochondrial ribosomal protein S33

chr2_-_145278475 0.007 ENST00000558170.2
 ZEB2
zinc finger E-box binding homeobox 2
chr14_-_21492251 0.006 ENST00000554398.1
 NDRG2
NDRG family member 2
chrX_+_119292467 0.006 ENST00000371388.3
 RHOXF2
Rhox homeobox family, member 2
chr4_+_4861385 0.005 ENST00000382723.4
 MSX1
msh homeobox 1
chr4_-_103266626 0.005 ENST00000356736.4
 SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr11_-_105892937 0.005 ENST00000301919.4
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
 MSANTD4



Myb/SANT-like DNA-binding domain containing 4 with coiled-coils



chr17_-_19651598 0.004 ENST00000570414.1
 ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr11_+_15136462 0.003 ENST00000379556.3
ENST00000424273.1
 INSC

inscuteable homolog (Drosophila)

chr17_+_47653178 0.003 ENST00000328741.5
 NXPH3
neurexophilin 3
chr17_+_41924511 0.003 ENST00000377203.4
ENST00000539718.1
ENST00000588884.1
ENST00000293396.8
ENST00000586233.1
 CD300LG




CD300 molecule-like family member g




chr1_-_27216729 0.001 ENST00000431781.2
ENST00000374135.4
 GPN2

GPN-loop GTPase 2

chr20_-_48770174 0.001 ENST00000341698.2
 TMEM189-UBE2V1
TMEM189-UBE2V1 readthrough
chr11_-_62439727 0.001 ENST00000528862.1
 C11orf48
chromosome 11 open reading frame 48
chr15_+_45694523 0.001 ENST00000305560.6
 SPATA5L1
spermatogenesis associated 5-like 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0 0.1 GO:0006550 isoleucine catabolic process(GO:0006550)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.0 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 0.1 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)