Motif ID: PPARA
Z-value: 1.517
Transcription factors associated with PPARA:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| PPARA | ENSG00000186951.12 | PPARA |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| PPARA | hg19_v2_chr22_+_46546494_46546525 | 0.82 | 6.4e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 5.2 | GO:1904106 | protein localization to microvillus(GO:1904106) |
| 0.4 | 1.2 | GO:1903568 | negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568) |
| 0.4 | 1.1 | GO:0001869 | regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869) |
| 0.3 | 1.1 | GO:0032972 | regulation of muscle filament sliding speed(GO:0032972) |
| 0.3 | 1.1 | GO:0019626 | short-chain fatty acid catabolic process(GO:0019626) |
| 0.3 | 0.8 | GO:0035359 | negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) |
| 0.3 | 1.1 | GO:0045209 | MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209) |
| 0.3 | 1.3 | GO:0006121 | mitochondrial electron transport, succinate to ubiquinone(GO:0006121) |
| 0.2 | 1.0 | GO:0070837 | dehydroascorbic acid transport(GO:0070837) |
| 0.2 | 1.2 | GO:0090164 | asymmetric Golgi ribbon formation(GO:0090164) |
| 0.2 | 4.4 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 0.2 | 1.7 | GO:0060437 | lung growth(GO:0060437) |
| 0.2 | 7.2 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 0.2 | 1.8 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
| 0.2 | 2.1 | GO:0031087 | deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
| 0.2 | 4.3 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.2 | 0.7 | GO:0009236 | cobalamin biosynthetic process(GO:0009236) |
| 0.2 | 2.6 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.2 | 0.5 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
| 0.2 | 0.5 | GO:0070676 | intralumenal vesicle formation(GO:0070676) |
| 0.2 | 0.5 | GO:0098507 | polynucleotide 5' dephosphorylation(GO:0098507) |
| 0.2 | 0.8 | GO:0017055 | negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) |
| 0.2 | 12.1 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.2 | 5.2 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
| 0.2 | 3.0 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 0.1 | 0.3 | GO:0002019 | regulation of renal output by angiotensin(GO:0002019) |
| 0.1 | 6.8 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.1 | 6.2 | GO:0016486 | peptide hormone processing(GO:0016486) |
| 0.1 | 1.5 | GO:0003190 | atrioventricular valve formation(GO:0003190) |
| 0.1 | 0.5 | GO:0061763 | multivesicular body-lysosome fusion(GO:0061763) |
| 0.1 | 0.4 | GO:0038163 | thrombopoietin-mediated signaling pathway(GO:0038163) |
| 0.1 | 1.1 | GO:0030242 | pexophagy(GO:0030242) |
| 0.1 | 0.8 | GO:0051005 | negative regulation of lipoprotein lipase activity(GO:0051005) |
| 0.1 | 0.6 | GO:0046440 | L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440) |
| 0.1 | 0.7 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
| 0.1 | 0.3 | GO:1904428 | negative regulation of tubulin deacetylation(GO:1904428) |
| 0.1 | 0.3 | GO:0003289 | atrial septum primum morphogenesis(GO:0003289) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) |
| 0.1 | 0.3 | GO:1901076 | positive regulation of engulfment of apoptotic cell(GO:1901076) |
| 0.1 | 1.1 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.1 | 0.3 | GO:0006106 | fumarate metabolic process(GO:0006106) |
| 0.1 | 0.3 | GO:0015680 | intracellular copper ion transport(GO:0015680) |
| 0.1 | 0.3 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
| 0.1 | 0.7 | GO:0060316 | positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
| 0.1 | 0.7 | GO:0015793 | glycerol transport(GO:0015793) |
| 0.1 | 0.4 | GO:0070844 | misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846) |
| 0.1 | 0.6 | GO:0030421 | defecation(GO:0030421) |
| 0.1 | 0.9 | GO:0003025 | regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564) |
| 0.1 | 0.6 | GO:0035026 | leading edge cell differentiation(GO:0035026) |
| 0.1 | 0.4 | GO:1990926 | short-term synaptic potentiation(GO:1990926) |
| 0.1 | 0.7 | GO:0044245 | polysaccharide digestion(GO:0044245) |
| 0.1 | 0.6 | GO:0097368 | establishment of Sertoli cell barrier(GO:0097368) |
| 0.1 | 1.2 | GO:0046886 | positive regulation of hormone biosynthetic process(GO:0046886) |
| 0.1 | 1.1 | GO:0014722 | regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) |
| 0.1 | 0.3 | GO:0060629 | regulation of homologous chromosome segregation(GO:0060629) |
| 0.1 | 0.4 | GO:0061198 | fungiform papilla formation(GO:0061198) |
| 0.1 | 0.2 | GO:0015729 | thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356) |
| 0.1 | 2.7 | GO:1901685 | glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687) |
| 0.1 | 0.6 | GO:1902162 | mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164) |
| 0.1 | 0.6 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 0.1 | 1.0 | GO:0006477 | protein sulfation(GO:0006477) |
| 0.1 | 0.6 | GO:0039663 | fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800) |
| 0.1 | 0.2 | GO:0060382 | regulation of DNA strand elongation(GO:0060382) |
| 0.1 | 0.2 | GO:0000961 | negative regulation of mitochondrial RNA catabolic process(GO:0000961) |
| 0.1 | 0.8 | GO:0048665 | neuron fate specification(GO:0048665) |
| 0.1 | 0.2 | GO:0001579 | medium-chain fatty acid transport(GO:0001579) |
| 0.1 | 0.3 | GO:0090214 | spongiotrophoblast layer developmental growth(GO:0090214) |
| 0.1 | 0.3 | GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919) |
| 0.1 | 0.4 | GO:0009257 | 10-formyltetrahydrofolate biosynthetic process(GO:0009257) |
| 0.1 | 0.6 | GO:1903764 | regulation of potassium ion export across plasma membrane(GO:1903764) |
| 0.1 | 0.2 | GO:0051168 | nuclear export(GO:0051168) |
| 0.1 | 1.4 | GO:0098828 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.1 | 0.9 | GO:0002091 | negative regulation of receptor internalization(GO:0002091) |
| 0.1 | 0.4 | GO:1903588 | negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588) |
| 0.1 | 0.2 | GO:0090158 | endoplasmic reticulum membrane organization(GO:0090158) |
| 0.1 | 0.4 | GO:0008218 | bioluminescence(GO:0008218) |
| 0.1 | 0.2 | GO:0016256 | N-glycan processing to lysosome(GO:0016256) |
| 0.1 | 0.3 | GO:0006546 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
| 0.1 | 0.2 | GO:2001301 | lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303) |
| 0.1 | 2.5 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
| 0.1 | 0.4 | GO:0090649 | response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) response to aldosterone(GO:1904044) |
| 0.1 | 0.8 | GO:0042407 | cristae formation(GO:0042407) |
| 0.1 | 0.4 | GO:0030997 | regulation of centriole-centriole cohesion(GO:0030997) |
| 0.1 | 0.5 | GO:1903593 | regulation of histamine secretion by mast cell(GO:1903593) |
| 0.1 | 0.2 | GO:0046166 | glyceraldehyde-3-phosphate biosynthetic process(GO:0046166) |
| 0.1 | 1.0 | GO:0090360 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
| 0.1 | 0.1 | GO:1904327 | protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379) |
| 0.1 | 0.6 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 0.1 | 1.0 | GO:0009313 | oligosaccharide catabolic process(GO:0009313) |
| 0.1 | 1.0 | GO:0055089 | fatty acid homeostasis(GO:0055089) |
| 0.0 | 0.5 | GO:0071493 | cellular response to UV-B(GO:0071493) |
| 0.0 | 0.5 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 0.0 | 0.9 | GO:0016559 | peroxisome fission(GO:0016559) |
| 0.0 | 0.3 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.0 | 0.5 | GO:1901387 | positive regulation of voltage-gated calcium channel activity(GO:1901387) |
| 0.0 | 0.2 | GO:0007341 | penetration of zona pellucida(GO:0007341) |
| 0.0 | 0.4 | GO:0032417 | positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885) |
| 0.0 | 0.3 | GO:0021993 | initiation of neural tube closure(GO:0021993) |
| 0.0 | 1.3 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 0.3 | GO:0006108 | malate metabolic process(GO:0006108) |
| 0.0 | 0.2 | GO:0042144 | vacuole fusion, non-autophagic(GO:0042144) |
| 0.0 | 0.1 | GO:1903760 | regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024) |
| 0.0 | 0.2 | GO:0044336 | canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336) |
| 0.0 | 0.7 | GO:0006527 | arginine catabolic process(GO:0006527) |
| 0.0 | 1.1 | GO:1901897 | regulation of relaxation of cardiac muscle(GO:1901897) |
| 0.0 | 0.3 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.0 | 0.1 | GO:0098912 | membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) |
| 0.0 | 0.6 | GO:1990778 | protein localization to cell periphery(GO:1990778) |
| 0.0 | 0.1 | GO:1900738 | positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) |
| 0.0 | 0.5 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 0.0 | 0.1 | GO:0070563 | negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420) |
| 0.0 | 0.1 | GO:0044335 | canonical Wnt signaling pathway involved in neural crest cell differentiation(GO:0044335) |
| 0.0 | 0.3 | GO:0070836 | caveola assembly(GO:0070836) |
| 0.0 | 0.3 | GO:0071028 | nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028) |
| 0.0 | 0.3 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
| 0.0 | 1.1 | GO:0015879 | carnitine transport(GO:0015879) |
| 0.0 | 0.8 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.0 | 0.1 | GO:1901491 | negative regulation of lymphangiogenesis(GO:1901491) |
| 0.0 | 0.3 | GO:0060075 | regulation of resting membrane potential(GO:0060075) |
| 0.0 | 1.4 | GO:0050435 | beta-amyloid metabolic process(GO:0050435) |
| 0.0 | 0.7 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
| 0.0 | 0.3 | GO:0019255 | glucose 1-phosphate metabolic process(GO:0019255) |
| 0.0 | 1.2 | GO:0090140 | regulation of mitochondrial fission(GO:0090140) |
| 0.0 | 0.8 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.0 | 0.2 | GO:1902255 | positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) positive regulation of protein monoubiquitination(GO:1902527) |
| 0.0 | 0.1 | GO:0060474 | positive regulation of sperm motility involved in capacitation(GO:0060474) |
| 0.0 | 0.2 | GO:0061589 | calcium activated phosphatidylserine scrambling(GO:0061589) |
| 0.0 | 0.4 | GO:0070070 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.0 | 0.2 | GO:0061732 | mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732) |
| 0.0 | 0.4 | GO:0032464 | positive regulation of protein homooligomerization(GO:0032464) |
| 0.0 | 0.5 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.0 | 0.4 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
| 0.0 | 0.1 | GO:0050894 | determination of affect(GO:0050894) |
| 0.0 | 0.8 | GO:0090005 | negative regulation of establishment of protein localization to plasma membrane(GO:0090005) |
| 0.0 | 0.1 | GO:1901842 | negative regulation of high voltage-gated calcium channel activity(GO:1901842) |
| 0.0 | 0.6 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.0 | 1.1 | GO:0061099 | negative regulation of protein tyrosine kinase activity(GO:0061099) |
| 0.0 | 0.2 | GO:2000467 | positive regulation of glycogen (starch) synthase activity(GO:2000467) |
| 0.0 | 1.0 | GO:0021522 | spinal cord motor neuron differentiation(GO:0021522) |
| 0.0 | 0.2 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.0 | 0.1 | GO:0034378 | chylomicron assembly(GO:0034378) |
| 0.0 | 0.2 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) protein localization to cytoplasmic stress granule(GO:1903608) |
| 0.0 | 0.1 | GO:0003100 | regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) |
| 0.0 | 0.2 | GO:0001976 | neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976) |
| 0.0 | 0.1 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
| 0.0 | 0.8 | GO:0006941 | striated muscle contraction(GO:0006941) |
| 0.0 | 0.5 | GO:0031065 | positive regulation of histone deacetylation(GO:0031065) |
| 0.0 | 0.2 | GO:1901998 | toxin transport(GO:1901998) |
| 0.0 | 0.3 | GO:1903077 | negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376) |
| 0.0 | 0.6 | GO:0051560 | mitochondrial calcium ion homeostasis(GO:0051560) |
| 0.0 | 1.3 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
| 0.0 | 0.4 | GO:0051683 | establishment of Golgi localization(GO:0051683) |
| 0.0 | 0.4 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.0 | 0.3 | GO:0021542 | dentate gyrus development(GO:0021542) |
| 0.0 | 0.2 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
| 0.0 | 0.3 | GO:0030214 | hyaluronan catabolic process(GO:0030214) |
| 0.0 | 0.2 | GO:1902037 | negative regulation of hematopoietic stem cell differentiation(GO:1902037) |
| 0.0 | 0.1 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
| 0.0 | 0.2 | GO:1903071 | positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
| 0.0 | 0.3 | GO:0034384 | high-density lipoprotein particle clearance(GO:0034384) |
| 0.0 | 0.1 | GO:2000609 | regulation of thyroid hormone generation(GO:2000609) |
| 0.0 | 0.3 | GO:0018342 | protein prenylation(GO:0018342) prenylation(GO:0097354) |
| 0.0 | 0.1 | GO:0002084 | protein depalmitoylation(GO:0002084) |
| 0.0 | 0.1 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
| 0.0 | 0.2 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 0.0 | 0.7 | GO:0006754 | ATP biosynthetic process(GO:0006754) |
| 0.0 | 0.1 | GO:0019303 | D-ribose catabolic process(GO:0019303) |
| 0.0 | 0.3 | GO:0031069 | hair follicle morphogenesis(GO:0031069) |
| 0.0 | 0.2 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 0.0 | 0.3 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 0.0 | 0.1 | GO:2000546 | positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546) |
| 0.0 | 0.2 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
| 0.0 | 0.1 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
| 0.0 | 0.2 | GO:1904322 | response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322) |
| 0.0 | 0.1 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 0.0 | 0.0 | GO:0090403 | oxidative stress-induced premature senescence(GO:0090403) |
| 0.0 | 0.2 | GO:0034374 | low-density lipoprotein particle remodeling(GO:0034374) |
| 0.0 | 0.8 | GO:0021762 | substantia nigra development(GO:0021762) |
| 0.0 | 0.3 | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
| 0.0 | 0.6 | GO:0007340 | acrosome reaction(GO:0007340) |
| 0.0 | 0.2 | GO:0060717 | chorion development(GO:0060717) |
| 0.0 | 0.0 | GO:0042631 | cellular response to water deprivation(GO:0042631) |
| 0.0 | 0.3 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.0 | 0.2 | GO:0045475 | locomotor rhythm(GO:0045475) |
| 0.0 | 0.2 | GO:0090308 | regulation of methylation-dependent chromatin silencing(GO:0090308) |
| 0.0 | 0.2 | GO:0015866 | ADP transport(GO:0015866) |
| 0.0 | 1.8 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.0 | 0.2 | GO:0033690 | positive regulation of osteoblast proliferation(GO:0033690) |
| 0.0 | 0.1 | GO:0003322 | pancreatic A cell development(GO:0003322) |
| 0.0 | 0.9 | GO:0019730 | antimicrobial humoral response(GO:0019730) |
| 0.0 | 0.0 | GO:1903280 | negative regulation of calcium:sodium antiporter activity(GO:1903280) |
| 0.0 | 0.8 | GO:0003254 | regulation of membrane depolarization(GO:0003254) |
| 0.0 | 0.5 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 0.0 | 0.2 | GO:0031272 | regulation of pseudopodium assembly(GO:0031272) |
| 0.0 | 0.4 | GO:0031032 | actomyosin structure organization(GO:0031032) |
| 0.0 | 0.0 | GO:0010902 | regulation of very-low-density lipoprotein particle remodeling(GO:0010901) positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902) |
| 0.0 | 0.2 | GO:0030323 | respiratory tube development(GO:0030323) |
| 0.0 | 0.5 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
| 0.0 | 0.1 | GO:0045725 | positive regulation of glycogen biosynthetic process(GO:0045725) positive regulation of glycogen metabolic process(GO:0070875) |
| 0.0 | 0.1 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
| 0.0 | 0.4 | GO:0006383 | transcription from RNA polymerase III promoter(GO:0006383) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 2.2 | GO:0045283 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
| 0.4 | 2.2 | GO:0045272 | plasma membrane respiratory chain complex I(GO:0045272) plasma membrane respiratory chain(GO:0070470) |
| 0.3 | 1.3 | GO:0031251 | PAN complex(GO:0031251) |
| 0.3 | 2.5 | GO:0045261 | proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
| 0.2 | 4.3 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.2 | 2.9 | GO:0045275 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.2 | 1.3 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
| 0.2 | 1.2 | GO:0005927 | muscle tendon junction(GO:0005927) |
| 0.2 | 2.4 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.2 | 0.3 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.1 | 9.8 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.1 | 0.5 | GO:0070033 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) |
| 0.1 | 0.4 | GO:0043291 | RAVE complex(GO:0043291) |
| 0.1 | 0.4 | GO:0005967 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) |
| 0.1 | 0.3 | GO:0005745 | m-AAA complex(GO:0005745) |
| 0.1 | 0.2 | GO:0043159 | acrosomal matrix(GO:0043159) |
| 0.1 | 0.9 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.1 | 0.5 | GO:1990037 | Lewy body core(GO:1990037) |
| 0.1 | 0.4 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
| 0.1 | 0.2 | GO:0036117 | hyaluranon cable(GO:0036117) |
| 0.1 | 1.0 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 0.1 | 0.6 | GO:0061617 | MICOS complex(GO:0061617) |
| 0.1 | 5.2 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.1 | 1.1 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.1 | 1.1 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.1 | 0.7 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 0.1 | 0.8 | GO:0098839 | postsynaptic density membrane(GO:0098839) |
| 0.1 | 0.6 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.1 | 0.4 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.0 | 0.6 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.0 | 4.4 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.0 | 0.2 | GO:0005784 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 0.0 | 1.4 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 6.1 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 0.2 | GO:0070931 | Golgi-associated vesicle lumen(GO:0070931) |
| 0.0 | 0.3 | GO:0045239 | tricarboxylic acid cycle enzyme complex(GO:0045239) |
| 0.0 | 0.3 | GO:0097452 | GAIT complex(GO:0097452) |
| 0.0 | 0.6 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.0 | 0.1 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.0 | 0.2 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.0 | 0.5 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.0 | 0.3 | GO:0044326 | dendritic spine neck(GO:0044326) |
| 0.0 | 1.1 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.0 | 0.6 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.0 | 0.9 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.0 | 0.3 | GO:0016013 | syntrophin complex(GO:0016013) |
| 0.0 | 0.3 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.0 | 1.4 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 1.9 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 0.5 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.0 | 0.4 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.0 | 0.3 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
| 0.0 | 0.6 | GO:0031304 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 0.0 | 0.2 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
| 0.0 | 0.2 | GO:1990393 | 3M complex(GO:1990393) |
| 0.0 | 0.4 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.0 | 1.6 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.0 | 0.5 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 0.0 | 5.5 | GO:0030018 | Z disc(GO:0030018) |
| 0.0 | 0.4 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 0.5 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.0 | 0.3 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
| 0.0 | 1.5 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 0.1 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 0.0 | 0.2 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.0 | 2.0 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 2.1 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 2.5 | GO:0005938 | cell cortex(GO:0005938) |
| 0.0 | 1.7 | GO:0005798 | Golgi-associated vesicle(GO:0005798) |
| 0.0 | 0.1 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 0.0 | 0.1 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.0 | 0.8 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.0 | 0.3 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.0 | 0.2 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.0 | 0.3 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.0 | 0.3 | GO:0034706 | sodium channel complex(GO:0034706) |
| 0.0 | 0.2 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 3.3 | GO:0009986 | cell surface(GO:0009986) |
| 0.0 | 0.3 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.0 | 0.1 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.0 | 0.1 | GO:0031430 | M band(GO:0031430) |
| 0.0 | 0.9 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 0.1 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.0 | 0.1 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
| 0.0 | 2.0 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.0 | 1.0 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 0.2 | GO:0042629 | mast cell granule(GO:0042629) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 2.2 | GO:0008177 | succinate dehydrogenase (ubiquinone) activity(GO:0008177) |
| 0.6 | 4.4 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.4 | 2.5 | GO:0043532 | angiostatin binding(GO:0043532) |
| 0.3 | 4.4 | GO:0004445 | inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) |
| 0.3 | 1.2 | GO:0004874 | aryl hydrocarbon receptor activity(GO:0004874) |
| 0.3 | 0.8 | GO:0016838 | carbon-oxygen lyase activity, acting on phosphates(GO:0016838) |
| 0.3 | 0.8 | GO:0004174 | electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649) |
| 0.2 | 1.0 | GO:0033300 | dehydroascorbic acid transporter activity(GO:0033300) |
| 0.2 | 1.6 | GO:0004466 | long-chain-acyl-CoA dehydrogenase activity(GO:0004466) |
| 0.2 | 0.8 | GO:0032427 | GBD domain binding(GO:0032427) |
| 0.2 | 12.7 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.2 | 1.5 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.2 | 0.8 | GO:0031811 | G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
| 0.2 | 0.5 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
| 0.2 | 0.5 | GO:0019959 | interleukin-8 binding(GO:0019959) |
| 0.2 | 0.3 | GO:0051538 | 3 iron, 4 sulfur cluster binding(GO:0051538) |
| 0.2 | 0.8 | GO:0010465 | nerve growth factor receptor activity(GO:0010465) |
| 0.2 | 0.5 | GO:0004651 | polynucleotide 5'-phosphatase activity(GO:0004651) |
| 0.2 | 0.7 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.2 | 1.1 | GO:0005124 | scavenger receptor binding(GO:0005124) |
| 0.1 | 0.7 | GO:0004556 | alpha-amylase activity(GO:0004556) |
| 0.1 | 6.3 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.1 | 0.4 | GO:0047025 | 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025) |
| 0.1 | 1.0 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
| 0.1 | 0.7 | GO:0008267 | poly-glutamine tract binding(GO:0008267) |
| 0.1 | 0.5 | GO:0052810 | 1-phosphatidylinositol-5-kinase activity(GO:0052810) |
| 0.1 | 0.4 | GO:0016418 | S-acetyltransferase activity(GO:0016418) |
| 0.1 | 1.3 | GO:0031014 | troponin T binding(GO:0031014) |
| 0.1 | 0.7 | GO:0015168 | glycerol transmembrane transporter activity(GO:0015168) |
| 0.1 | 0.6 | GO:0003986 | acetyl-CoA hydrolase activity(GO:0003986) |
| 0.1 | 3.7 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.1 | 1.9 | GO:0015377 | cation:chloride symporter activity(GO:0015377) |
| 0.1 | 0.3 | GO:0045155 | electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155) |
| 0.1 | 1.1 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.1 | 0.7 | GO:0035473 | lipase binding(GO:0035473) |
| 0.1 | 0.4 | GO:0050252 | retinol O-fatty-acyltransferase activity(GO:0050252) |
| 0.1 | 0.7 | GO:0016403 | dimethylargininase activity(GO:0016403) |
| 0.1 | 0.3 | GO:0008431 | vitamin E binding(GO:0008431) |
| 0.1 | 0.5 | GO:0008665 | 2'-phosphotransferase activity(GO:0008665) |
| 0.1 | 0.6 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
| 0.1 | 0.6 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
| 0.1 | 0.3 | GO:0034353 | RNA pyrophosphohydrolase activity(GO:0034353) |
| 0.1 | 0.4 | GO:0052593 | tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596) |
| 0.1 | 1.1 | GO:0004075 | biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374) |
| 0.1 | 2.7 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.1 | 5.2 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.1 | 0.3 | GO:0034188 | apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556) |
| 0.1 | 0.2 | GO:0015117 | thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) |
| 0.1 | 0.3 | GO:0016532 | superoxide dismutase copper chaperone activity(GO:0016532) |
| 0.1 | 0.3 | GO:0043891 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891) |
| 0.1 | 2.0 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.1 | 0.3 | GO:0004047 | aminomethyltransferase activity(GO:0004047) |
| 0.1 | 0.4 | GO:0052740 | 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740) |
| 0.1 | 0.2 | GO:0033867 | Fas-activated serine/threonine kinase activity(GO:0033867) |
| 0.1 | 0.2 | GO:0004807 | triose-phosphate isomerase activity(GO:0004807) |
| 0.1 | 0.4 | GO:0004329 | formate-tetrahydrofolate ligase activity(GO:0004329) |
| 0.1 | 0.7 | GO:0003997 | acyl-CoA oxidase activity(GO:0003997) |
| 0.1 | 0.2 | GO:0050613 | delta14-sterol reductase activity(GO:0050613) |
| 0.1 | 0.1 | GO:0003955 | NAD(P)H dehydrogenase (quinone) activity(GO:0003955) |
| 0.1 | 2.4 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.1 | 0.4 | GO:0042903 | tubulin deacetylase activity(GO:0042903) |
| 0.1 | 0.2 | GO:0016165 | linoleate 13S-lipoxygenase activity(GO:0016165) hepoxilin-epoxide hydrolase activity(GO:0047977) |
| 0.1 | 1.1 | GO:0004723 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) |
| 0.1 | 0.4 | GO:0008401 | retinoic acid 4-hydroxylase activity(GO:0008401) |
| 0.1 | 1.7 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.1 | 6.4 | GO:0005179 | hormone activity(GO:0005179) |
| 0.1 | 1.1 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.1 | 1.1 | GO:0005537 | mannose binding(GO:0005537) |
| 0.1 | 0.5 | GO:0008948 | oxaloacetate decarboxylase activity(GO:0008948) |
| 0.1 | 0.5 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
| 0.1 | 0.2 | GO:1990175 | EH domain binding(GO:1990175) |
| 0.1 | 0.6 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.0 | 1.3 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.0 | 1.4 | GO:0008242 | omega peptidase activity(GO:0008242) |
| 0.0 | 0.5 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.0 | 0.2 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
| 0.0 | 0.6 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.0 | 0.2 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 0.0 | 0.3 | GO:0051748 | UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748) |
| 0.0 | 0.3 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.0 | 1.3 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 1.3 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
| 0.0 | 1.2 | GO:0008171 | O-methyltransferase activity(GO:0008171) |
| 0.0 | 0.7 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
| 0.0 | 0.1 | GO:0004800 | thyroxine 5'-deiodinase activity(GO:0004800) |
| 0.0 | 2.4 | GO:0015078 | hydrogen ion transmembrane transporter activity(GO:0015078) |
| 0.0 | 0.1 | GO:0086062 | voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062) |
| 0.0 | 0.9 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.0 | 0.5 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.0 | 0.3 | GO:0008318 | protein prenyltransferase activity(GO:0008318) |
| 0.0 | 0.4 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 0.0 | 0.1 | GO:0031877 | somatostatin receptor binding(GO:0031877) |
| 0.0 | 0.1 | GO:0033878 | hormone-sensitive lipase activity(GO:0033878) |
| 0.0 | 0.3 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
| 0.0 | 0.2 | GO:0034604 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604) |
| 0.0 | 0.9 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.0 | 0.6 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.0 | 2.1 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.0 | 0.2 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.0 | 0.3 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.0 | 0.1 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 0.0 | 0.5 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.0 | 0.5 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) |
| 0.0 | 0.3 | GO:0031748 | D1 dopamine receptor binding(GO:0031748) |
| 0.0 | 0.2 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.0 | 0.1 | GO:0002046 | opsin binding(GO:0002046) |
| 0.0 | 0.2 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 0.0 | 0.1 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.0 | 0.6 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.0 | 0.3 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 0.0 | 0.3 | GO:0031702 | angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702) |
| 0.0 | 0.2 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.0 | 0.4 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 0.6 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
| 0.0 | 0.5 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.0 | 0.1 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 0.0 | 2.2 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.3 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.0 | 0.9 | GO:0008146 | sulfotransferase activity(GO:0008146) |
| 0.0 | 0.1 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
| 0.0 | 0.3 | GO:0050998 | nitric-oxide synthase binding(GO:0050998) |
| 0.0 | 0.1 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.0 | 0.2 | GO:0015217 | ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217) |
| 0.0 | 1.2 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.0 | 0.4 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 0.3 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
| 0.0 | 3.0 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.4 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.0 | 0.8 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.0 | 0.8 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.0 | 0.3 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
| 0.0 | 0.1 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.0 | 0.3 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
| 0.0 | 0.2 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.0 | 0.1 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.0 | 0.2 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
| 0.0 | 0.8 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.0 | 2.0 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.0 | ST_MYOCYTE_AD_PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 0.5 | PID_ATF2_PATHWAY | ATF-2 transcription factor network |
| 0.0 | 0.3 | ST_TYPE_I_INTERFERON_PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
| 0.0 | 1.3 | PID_HIF1A_PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 2.0 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
| 0.0 | 1.1 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 1.0 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.0 | 3.9 | PID_REG_GR_PATHWAY | Glucocorticoid receptor regulatory network |
| 0.0 | 1.4 | PID_INTEGRIN2_PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 1.0 | PID_P38_ALPHA_BETA_PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.0 | 0.6 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
| 0.0 | 0.7 | PID_SYNDECAN_2_PATHWAY | Syndecan-2-mediated signaling events |
| 0.0 | 0.5 | PID_WNT_CANONICAL_PATHWAY | Canonical Wnt signaling pathway |
| 0.0 | 0.5 | PID_P73PATHWAY | p73 transcription factor network |
| 0.0 | 0.2 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
| 0.0 | 1.1 | WNT_SIGNALING | Genes related to Wnt-mediated signal transduction |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 6.4 | REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS | Genes involved in Peptide hormone biosynthesis |
| 0.2 | 21.4 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
| 0.2 | 5.6 | REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
| 0.2 | 3.1 | REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.1 | 0.6 | REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION | Genes involved in Binding and entry of HIV virion |
| 0.1 | 2.3 | REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
| 0.1 | 1.6 | REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.1 | 4.6 | REACTOME_CGMP_EFFECTS | Genes involved in cGMP effects |
| 0.1 | 0.6 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 0.1 | 1.7 | REACTOME_ACTIVATED_POINT_MUTANTS_OF_FGFR2 | Genes involved in Activated point mutants of FGFR2 |
| 0.1 | 0.1 | REACTOME_SHC_MEDIATED_SIGNALLING | Genes involved in SHC-mediated signalling |
| 0.1 | 4.3 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.1 | 0.7 | REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.1 | 2.7 | REACTOME_GLUTATHIONE_CONJUGATION | Genes involved in Glutathione conjugation |
| 0.1 | 1.2 | REACTOME_INTRINSIC_PATHWAY | Genes involved in Intrinsic Pathway |
| 0.0 | 0.9 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.0 | 1.0 | REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.0 | 0.9 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
| 0.0 | 0.9 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.0 | 0.7 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
| 0.0 | 0.3 | REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 0.0 | 0.6 | REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.0 | 1.6 | REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM | Genes involved in Chondroitin sulfate/dermatan sulfate metabolism |
| 0.0 | 0.7 | REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.0 | 1.0 | REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
| 0.0 | 0.7 | REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.0 | 0.4 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
| 0.0 | 1.6 | REACTOME_AMYLOIDS | Genes involved in Amyloids |
| 0.0 | 1.4 | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.0 | 0.3 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.0 | 0.4 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.0 | 0.3 | REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.0 | 0.3 | REACTOME_IL_6_SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.0 | 0.5 | REACTOME_MRNA_CAPPING | Genes involved in mRNA Capping |
| 0.0 | 0.1 | REACTOME_BETA_DEFENSINS | Genes involved in Beta defensins |
| 0.0 | 0.6 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 0.2 | REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.0 | 0.5 | REACTOME_ACTIVATION_OF_GENES_BY_ATF4 | Genes involved in Activation of Genes by ATF4 |
| 0.0 | 1.0 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 0.4 | REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A | Genes involved in APC-Cdc20 mediated degradation of Nek2A |
| 0.0 | 0.1 | REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.0 | 0.4 | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| 0.0 | 0.2 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
