Motif ID: POU6F1

Z-value: 0.385


Transcription factors associated with POU6F1:

Gene SymbolEntrez IDGene Name
POU6F1 ENSG00000184271.11 POU6F1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
POU6F1hg19_v2_chr12_-_51611477_51611612-0.245.3e-01Click!


Activity profile for motif POU6F1.

activity profile for motif POU6F1


Sorted Z-values histogram for motif POU6F1

Sorted Z-values for motif POU6F1



Network of associatons between targets according to the STRING database.



First level regulatory network of POU6F1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_49297899 0.232 ENST00000552942.1
ENST00000320516.4
 CCDC65

coiled-coil domain containing 65

chr14_-_70883708 0.172 ENST00000256366.4
 SYNJ2BP
synaptojanin 2 binding protein
chr6_-_111136513 0.161 ENST00000368911.3
 CDK19
cyclin-dependent kinase 19
chr13_-_52027134 0.145 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
 INTS6




integrator complex subunit 6




chrX_-_122756660 0.136 ENST00000441692.1
 THOC2
THO complex 2
chr6_-_111136299 0.134 ENST00000457688.1
 CDK19
cyclin-dependent kinase 19
chr15_+_80351977 0.124 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
 ZFAND6



zinc finger, AN1-type domain 6



chr12_+_49297887 0.119 ENST00000266984.5
 CCDC65
coiled-coil domain containing 65
chr12_+_102514019 0.118 ENST00000537257.1
ENST00000358383.5
ENST00000392911.2
 PARPBP


PARP1 binding protein


chr12_+_102513950 0.116 ENST00000378128.3
ENST00000327680.2
ENST00000541394.1
ENST00000543784.1
 PARPBP



PARP1 binding protein



chr9_-_131644306 0.104 ENST00000302586.3
 CCBL1
cysteine conjugate-beta lyase, cytoplasmic
chr6_-_74231444 0.099 ENST00000331523.2
ENST00000356303.2
 EEF1A1

eukaryotic translation elongation factor 1 alpha 1

chr15_-_85259330 0.099 ENST00000560266.1
 SEC11A
SEC11 homolog A (S. cerevisiae)
chr15_-_85259384 0.096 ENST00000455959.3
 SEC11A
SEC11 homolog A (S. cerevisiae)
chr5_+_162864575 0.095 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
 CCNG1






cyclin G1






chr6_-_110501200 0.092 ENST00000392586.1
ENST00000419252.1
ENST00000392589.1
ENST00000392588.1
ENST00000359451.2
 WASF1




WAS protein family, member 1




chr15_+_80351910 0.092 ENST00000261749.6
ENST00000561060.1
 ZFAND6

zinc finger, AN1-type domain 6

chr1_-_197115818 0.092 ENST00000367409.4
ENST00000294732.7
 ASPM

asp (abnormal spindle) homolog, microcephaly associated (Drosophila)

chr13_+_98612446 0.091 ENST00000496368.1
ENST00000421861.2
ENST00000357602.3
 IPO5


importin 5


chr15_-_85259294 0.090 ENST00000558217.1
ENST00000558196.1
ENST00000558134.1
 SEC11A


SEC11 homolog A (S. cerevisiae)


chr6_-_110501126 0.087 ENST00000368938.1
 WASF1
WAS protein family, member 1
chr9_+_128509624 0.086 ENST00000342287.5
ENST00000373487.4
 PBX3

pre-B-cell leukemia homeobox 3

chr15_-_85259360 0.082 ENST00000559729.1
 SEC11A
SEC11 homolog A (S. cerevisiae)
chr11_+_85339623 0.081 ENST00000358867.6
ENST00000534341.1
ENST00000393375.1
ENST00000531274.1
 TMEM126B



transmembrane protein 126B



chr9_-_131644202 0.080 ENST00000320665.6
ENST00000436267.2
 CCBL1

cysteine conjugate-beta lyase, cytoplasmic

chr15_-_44828838 0.079 ENST00000560750.1
 EIF3J-AS1
EIF3J antisense RNA 1 (head to head)
chr1_-_161008697 0.079 ENST00000318289.10
ENST00000368023.3
ENST00000368024.1
ENST00000423014.2
 TSTD1



thiosulfate sulfurtransferase (rhodanese)-like domain containing 1



chr12_-_95397442 0.076 ENST00000547157.1
ENST00000547986.1
ENST00000327772.2
 NDUFA12


NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12


chr2_+_207220463 0.074 ENST00000598562.1
 AC017081.1
Uncharacterized protein
chr22_+_31518938 0.070 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
 INPP5J






inositol polyphosphate-5-phosphatase J






chr2_-_166060552 0.069 ENST00000283254.7
ENST00000453007.1
 SCN3A

sodium channel, voltage-gated, type III, alpha subunit

chr7_+_80267973 0.068 ENST00000394788.3
ENST00000447544.2
 CD36

CD36 molecule (thrombospondin receptor)

chr17_-_30186328 0.066 ENST00000302362.6
 COPRS
coordinator of PRMT5, differentiation stimulator
chr6_-_111804905 0.066 ENST00000358835.3
ENST00000435970.1
 REV3L

REV3-like, polymerase (DNA directed), zeta, catalytic subunit

chr11_-_93583697 0.064 ENST00000409977.1
 VSTM5
V-set and transmembrane domain containing 5
chr1_-_222014008 0.064 ENST00000431729.1
 RP11-191N8.2
RP11-191N8.2
chr1_+_225117350 0.063 ENST00000413949.2
ENST00000430092.1
ENST00000366850.3
ENST00000400952.3
ENST00000366849.1
 DNAH14




dynein, axonemal, heavy chain 14




chr6_+_26183958 0.062 ENST00000356530.3
 HIST1H2BE
histone cluster 1, H2be
chr7_-_38407770 0.060 ENST00000390348.2
 TRGV1
T cell receptor gamma variable 1 (non-functional)
chr19_+_42817527 0.060 ENST00000598766.1
 TMEM145
transmembrane protein 145
chr15_+_45028719 0.060 ENST00000560442.1
ENST00000558329.1
ENST00000561043.1
 TRIM69


tripartite motif containing 69


chr17_-_39677971 0.060 ENST00000393976.2
 KRT15
keratin 15
chr9_+_26746951 0.056 ENST00000523363.1
 RP11-18A15.1
RP11-18A15.1
chr20_+_34129770 0.055 ENST00000348547.2
ENST00000357394.4
ENST00000447986.1
ENST00000279052.6
ENST00000416206.1
ENST00000411577.1
ENST00000413587.1
 ERGIC3






ERGIC and golgi 3






chr7_-_77427676 0.055 ENST00000257663.3
 TMEM60
transmembrane protein 60
chr7_+_48494660 0.054 ENST00000411975.1
ENST00000544596.1
 ABCA13

ATP-binding cassette, sub-family A (ABC1), member 13

chr9_-_13165457 0.051 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
 MPDZ


multiple PDZ domain protein


chr18_+_9475001 0.051 ENST00000019317.4
 RALBP1
ralA binding protein 1
chr1_-_21377383 0.049 ENST00000374935.3
 EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chrX_+_43515467 0.049 ENST00000338702.3
ENST00000542639.1
 MAOA

monoamine oxidase A

chr8_-_10512569 0.048 ENST00000382483.3
 RP1L1
retinitis pigmentosa 1-like 1
chr14_+_39944025 0.047 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
 RP11-111A21.1


RP11-111A21.1


chr12_-_57443886 0.047 ENST00000300119.3
 MYO1A
myosin IA
chr4_+_110749143 0.044 ENST00000317735.4
 RRH
retinal pigment epithelium-derived rhodopsin homolog
chrX_+_102024075 0.042 ENST00000431616.1
ENST00000440496.1
ENST00000420471.1
ENST00000435966.1
 LINC00630



long intergenic non-protein coding RNA 630



chr9_-_86955598 0.040 ENST00000376238.4
 SLC28A3
solute carrier family 28 (concentrative nucleoside transporter), member 3
chr2_-_166060382 0.040 ENST00000409101.3
 SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr15_+_45028753 0.036 ENST00000338264.4
 TRIM69
tripartite motif containing 69
chr3_+_121289551 0.036 ENST00000334384.3
 ARGFX
arginine-fifty homeobox
chr17_-_26972126 0.036 ENST00000528896.2
 KIAA0100
KIAA0100
chr11_-_107729504 0.035 ENST00000265836.7
 SLC35F2
solute carrier family 35, member F2
chr19_-_58662139 0.035 ENST00000598312.1
 ZNF329
zinc finger protein 329
chr11_-_2323089 0.033 ENST00000456145.2
 C11orf21
chromosome 11 open reading frame 21
chr1_+_225140372 0.033 ENST00000366848.1
ENST00000439375.2
 DNAH14

dynein, axonemal, heavy chain 14

chr15_-_31283618 0.033 ENST00000563714.1
 MTMR10
myotubularin related protein 10
chr9_-_4666421 0.032 ENST00000381895.5
 SPATA6L
spermatogenesis associated 6-like
chr6_-_47010061 0.032 ENST00000371253.2
 GPR110
G protein-coupled receptor 110
chr10_+_18041218 0.032 ENST00000480516.1
ENST00000457860.1
 TMEM236

TMEM236

chr5_+_55147205 0.031 ENST00000396836.2
ENST00000396834.1
ENST00000447346.2
ENST00000359040.5
 IL31RA



interleukin 31 receptor A



chr2_-_166060571 0.030 ENST00000360093.3
 SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr15_-_88247083 0.029 ENST00000560439.1
 RP11-648K4.2
RP11-648K4.2
chr4_-_120222076 0.028 ENST00000504110.1
 C4orf3
chromosome 4 open reading frame 3
chr3_-_108248169 0.028 ENST00000273353.3
 MYH15
myosin, heavy chain 15
chr2_+_191045656 0.027 ENST00000443551.2
 C2orf88
chromosome 2 open reading frame 88
chr11_-_107729287 0.026 ENST00000375682.4
 SLC35F2
solute carrier family 35, member F2
chr1_-_243326612 0.025 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
 CEP170


centrosomal protein 170kDa


chr2_+_191045562 0.025 ENST00000340623.4
 C2orf88
chromosome 2 open reading frame 88
chr20_+_58515417 0.025 ENST00000360816.3
 FAM217B
family with sequence similarity 217, member B
chr2_-_217560248 0.023 ENST00000233813.4
 IGFBP5
insulin-like growth factor binding protein 5
chr20_+_5987890 0.023 ENST00000378868.4
 CRLS1
cardiolipin synthase 1
chr9_-_4666337 0.022 ENST00000381890.5
 SPATA6L
spermatogenesis associated 6-like
chr1_-_151431674 0.022 ENST00000531094.1
 POGZ
pogo transposable element with ZNF domain
chr7_-_83824449 0.021 ENST00000420047.1
 SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr2_-_202562774 0.021 ENST00000396886.3
ENST00000409143.1
 MPP4

membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)

chr11_-_107729887 0.020 ENST00000525815.1
 SLC35F2
solute carrier family 35, member F2
chr2_-_99917639 0.020 ENST00000308528.4
 LYG1
lysozyme G-like 1
chr21_-_31874435 0.020 ENST00000334151.2
 KRTAP19-5
keratin associated protein 19-5
chr4_-_130692631 0.019 ENST00000500092.2
ENST00000509105.1
 RP11-519M16.1

RP11-519M16.1

chr2_+_242289502 0.019 ENST00000451310.1
 SEPT2
septin 2
chr1_+_176432298 0.019 ENST00000367661.3
ENST00000367662.3
 PAPPA2

pappalysin 2

chr3_-_127541194 0.018 ENST00000453507.2
 MGLL
monoglyceride lipase
chr1_-_151431647 0.017 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
 POGZ




pogo transposable element with ZNF domain




chr6_-_138539627 0.017 ENST00000527246.2
 PBOV1
prostate and breast cancer overexpressed 1
chr4_+_40201954 0.017 ENST00000511121.1
 RHOH
ras homolog family member H
chr13_+_58206655 0.015 ENST00000377918.3
 PCDH17
protocadherin 17
chrX_+_119737806 0.014 ENST00000371317.5
 MCTS1
malignant T cell amplified sequence 1
chr1_-_151431909 0.012 ENST00000361398.3
ENST00000271715.2
 POGZ

pogo transposable element with ZNF domain

chr4_-_76912070 0.012 ENST00000395711.4
ENST00000356260.5
 SDAD1

SDA1 domain containing 1

chr2_+_128403720 0.012 ENST00000272644.3
 GPR17
G protein-coupled receptor 17
chr15_+_45028520 0.011 ENST00000329464.4
 TRIM69
tripartite motif containing 69
chr12_+_54892550 0.011 ENST00000545638.2
 NCKAP1L
NCK-associated protein 1-like
chr2_-_202563414 0.011 ENST00000409474.3
ENST00000315506.7
ENST00000359962.5
 MPP4


membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)


chr3_-_48659193 0.009 ENST00000330862.3
 TMEM89
transmembrane protein 89
chr1_-_106161540 0.008 ENST00000420901.1
ENST00000610126.1
ENST00000435253.2
 RP11-251P6.1


RP11-251P6.1


chr11_-_89224139 0.007 ENST00000413594.2
 NOX4
NADPH oxidase 4
chr9_-_118687405 0.007 ENST00000374014.3
 LINC00474
long intergenic non-protein coding RNA 474
chr6_-_26235206 0.007 ENST00000244534.5
 HIST1H1D
histone cluster 1, H1d
chr20_+_58203664 0.006 ENST00000541461.1
 PHACTR3
phosphatase and actin regulator 3
chr2_-_179516225 0.006 ENST00000446966.1
ENST00000426232.1
 TTN

titin

chr9_+_12685439 0.006 ENST00000473763.1
 TYRP1
tyrosinase-related protein 1
chr7_+_157318477 0.006 ENST00000444154.1
 AC006372.1
AC006372.1
chr12_+_15699286 0.006 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
 PTPRO



protein tyrosine phosphatase, receptor type, O



chr3_+_46395219 0.005 ENST00000445132.2
ENST00000292301.4
 CCR2

chemokine (C-C motif) receptor 2

chr11_+_12302492 0.005 ENST00000533534.1
 MICALCL
MICAL C-terminal like
chr2_+_11679963 0.005 ENST00000263834.5
 GREB1
growth regulation by estrogen in breast cancer 1
chr22_-_32767017 0.005 ENST00000400234.1
 RFPL3S
RFPL3 antisense
chr2_+_128403439 0.005 ENST00000544369.1
 GPR17
G protein-coupled receptor 17
chr16_+_15744078 0.004 ENST00000396354.1
ENST00000570727.1
 NDE1

nudE neurodevelopment protein 1

chr8_+_39792474 0.004 ENST00000502986.2
 IDO2
indoleamine 2,3-dioxygenase 2
chr14_-_23103716 0.004 ENST00000540461.1
 OR6J1
olfactory receptor, family 6, subfamily J, member 1 (gene/pseudogene)
chrX_-_100129320 0.003 ENST00000372966.3
 NOX1
NADPH oxidase 1
chr10_-_94257512 0.002 ENST00000371581.5
 IDE
insulin-degrading enzyme
chr2_-_202562716 0.002 ENST00000428900.2
 MPP4
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chrX_-_100129128 0.002 ENST00000372960.4
ENST00000372964.1
ENST00000217885.5
 NOX1


NADPH oxidase 1


chr10_-_43904235 0.001 ENST00000356053.3
 HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr10_+_97803151 0.000 ENST00000403870.3
ENST00000265992.5
ENST00000465148.2
ENST00000534974.1
 CCNJ



cyclin J



chr2_+_202937972 0.000 ENST00000541917.1
ENST00000295844.3
 AC079354.1

uncharacterized protein KIAA2012


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.4 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin