Motif ID: POU5F1_POU2F3
Z-value: 1.460
Transcription factors associated with POU5F1_POU2F3:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| POU2F3 | ENSG00000137709.5 | POU2F3 |
| POU5F1 | ENSG00000204531.11 | POU5F1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| POU5F1 | hg19_v2_chr6_-_31138439_31138475 | 0.82 | 7.0e-03 | Click! |
| POU2F3 | hg19_v2_chr11_+_120107344_120107351 | 0.19 | 6.2e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 2.2 | GO:0061289 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
| 0.5 | 3.1 | GO:0035026 | leading edge cell differentiation(GO:0035026) |
| 0.5 | 4.1 | GO:0009820 | alkaloid metabolic process(GO:0009820) |
| 0.5 | 1.5 | GO:0042214 | terpene metabolic process(GO:0042214) |
| 0.5 | 3.7 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.4 | 4.4 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.3 | 1.7 | GO:1905167 | positive regulation of lysosomal protein catabolic process(GO:1905167) |
| 0.3 | 1.7 | GO:0008050 | female courtship behavior(GO:0008050) |
| 0.3 | 5.2 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.3 | 1.6 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
| 0.3 | 4.0 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
| 0.3 | 1.3 | GO:1903615 | regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615) |
| 0.2 | 3.3 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.2 | 1.4 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
| 0.2 | 1.1 | GO:0072709 | cellular response to sorbitol(GO:0072709) |
| 0.2 | 3.3 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 0.2 | 1.4 | GO:0007598 | blood coagulation, extrinsic pathway(GO:0007598) |
| 0.2 | 1.8 | GO:0070235 | regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.2 | 0.6 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 0.2 | 0.5 | GO:1903348 | positive regulation of bicellular tight junction assembly(GO:1903348) |
| 0.2 | 0.5 | GO:0016260 | selenocysteine biosynthetic process(GO:0016260) |
| 0.2 | 0.5 | GO:1990709 | maintenance of synapse structure(GO:0099558) presynaptic active zone organization(GO:1990709) |
| 0.2 | 0.5 | GO:0035408 | histone H3-T6 phosphorylation(GO:0035408) |
| 0.2 | 0.3 | GO:0051673 | membrane disruption in other organism(GO:0051673) |
| 0.1 | 1.3 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 0.1 | 0.6 | GO:0048665 | neuron fate specification(GO:0048665) |
| 0.1 | 0.7 | GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
| 0.1 | 0.8 | GO:0016480 | negative regulation of transcription from RNA polymerase III promoter(GO:0016480) |
| 0.1 | 0.5 | GO:0060940 | epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940) |
| 0.1 | 0.8 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 0.1 | 0.4 | GO:0002731 | negative regulation of dendritic cell cytokine production(GO:0002731) |
| 0.1 | 0.6 | GO:0090370 | negative regulation of cholesterol efflux(GO:0090370) |
| 0.1 | 0.3 | GO:0035905 | ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) |
| 0.1 | 0.7 | GO:0090324 | negative regulation of oxidative phosphorylation(GO:0090324) |
| 0.1 | 0.3 | GO:0006043 | glucosamine catabolic process(GO:0006043) |
| 0.1 | 1.0 | GO:0003190 | atrioventricular valve formation(GO:0003190) |
| 0.1 | 0.5 | GO:0018101 | protein citrullination(GO:0018101) histone citrullination(GO:0036414) |
| 0.1 | 1.8 | GO:2000774 | positive regulation of cellular senescence(GO:2000774) |
| 0.1 | 1.3 | GO:0036155 | acylglycerol acyl-chain remodeling(GO:0036155) |
| 0.1 | 0.3 | GO:0051097 | negative regulation of helicase activity(GO:0051097) |
| 0.1 | 0.6 | GO:0072675 | multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675) |
| 0.1 | 1.0 | GO:0021520 | spinal cord motor neuron cell fate specification(GO:0021520) |
| 0.1 | 0.3 | GO:1904428 | negative regulation of tubulin deacetylation(GO:1904428) |
| 0.1 | 0.4 | GO:0046440 | L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440) |
| 0.1 | 1.0 | GO:0033004 | negative regulation of mast cell activation(GO:0033004) |
| 0.1 | 0.7 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
| 0.1 | 0.2 | GO:0060741 | prostate gland stromal morphogenesis(GO:0060741) |
| 0.1 | 1.1 | GO:0072189 | ureter development(GO:0072189) |
| 0.1 | 3.8 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.1 | 0.2 | GO:1903450 | regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452) |
| 0.1 | 0.3 | GO:0031296 | B cell costimulation(GO:0031296) |
| 0.1 | 0.1 | GO:0072683 | T cell extravasation(GO:0072683) |
| 0.1 | 0.6 | GO:0003263 | cardioblast proliferation(GO:0003263) regulation of cardioblast proliferation(GO:0003264) |
| 0.1 | 0.2 | GO:0046081 | dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081) |
| 0.1 | 0.9 | GO:1902746 | regulation of lens fiber cell differentiation(GO:1902746) |
| 0.1 | 0.3 | GO:2000435 | regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435) |
| 0.1 | 0.5 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 0.1 | 1.4 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.1 | 0.3 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 0.1 | 1.1 | GO:0060056 | mammary gland involution(GO:0060056) |
| 0.1 | 0.3 | GO:0019075 | virus maturation(GO:0019075) |
| 0.1 | 0.4 | GO:0031179 | peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179) |
| 0.1 | 0.5 | GO:0002082 | regulation of oxidative phosphorylation(GO:0002082) |
| 0.1 | 0.2 | GO:0032915 | positive regulation of transforming growth factor beta2 production(GO:0032915) |
| 0.1 | 0.3 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 0.1 | 0.5 | GO:0010908 | regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730) |
| 0.1 | 1.4 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 0.1 | 0.4 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
| 0.1 | 0.5 | GO:0003025 | regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564) |
| 0.1 | 0.2 | GO:0010133 | proline catabolic process to glutamate(GO:0010133) |
| 0.1 | 0.4 | GO:2000402 | negative regulation of lymphocyte migration(GO:2000402) |
| 0.1 | 0.2 | GO:0060648 | fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) mammary gland specification(GO:0060594) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) mammary gland bud morphogenesis(GO:0060648) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915) |
| 0.1 | 0.6 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
| 0.1 | 1.2 | GO:0098828 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.1 | 0.2 | GO:0046022 | positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022) |
| 0.1 | 0.3 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
| 0.1 | 0.2 | GO:0021823 | cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) |
| 0.1 | 0.2 | GO:0007290 | spermatid nucleus elongation(GO:0007290) |
| 0.1 | 1.3 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 0.1 | 0.5 | GO:0097105 | presynaptic membrane assembly(GO:0097105) |
| 0.1 | 0.5 | GO:0031120 | snRNA pseudouridine synthesis(GO:0031120) |
| 0.1 | 1.6 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
| 0.0 | 0.6 | GO:0045876 | positive regulation of sister chromatid cohesion(GO:0045876) |
| 0.0 | 0.2 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 0.0 | 0.3 | GO:0072658 | maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 0.0 | 0.2 | GO:0042495 | detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340) |
| 0.0 | 0.7 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 0.0 | 0.1 | GO:1903031 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
| 0.0 | 0.4 | GO:0061591 | calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591) |
| 0.0 | 0.3 | GO:0021993 | initiation of neural tube closure(GO:0021993) |
| 0.0 | 0.4 | GO:0038031 | non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) |
| 0.0 | 0.3 | GO:0006642 | triglyceride mobilization(GO:0006642) |
| 0.0 | 0.1 | GO:0019442 | tryptophan catabolic process to acetyl-CoA(GO:0019442) L-kynurenine metabolic process(GO:0097052) |
| 0.0 | 0.1 | GO:0046041 | ITP metabolic process(GO:0046041) |
| 0.0 | 0.2 | GO:0009257 | 10-formyltetrahydrofolate biosynthetic process(GO:0009257) |
| 0.0 | 0.5 | GO:0030091 | protein repair(GO:0030091) |
| 0.0 | 1.2 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
| 0.0 | 0.1 | GO:0007057 | spindle assembly involved in female meiosis I(GO:0007057) |
| 0.0 | 0.4 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
| 0.0 | 0.3 | GO:1904936 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
| 0.0 | 1.2 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
| 0.0 | 0.5 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.0 | 0.1 | GO:0044026 | DNA hypermethylation(GO:0044026) hypermethylation of CpG island(GO:0044027) |
| 0.0 | 0.1 | GO:0003050 | regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050) |
| 0.0 | 0.3 | GO:1902896 | terminal web assembly(GO:1902896) |
| 0.0 | 0.2 | GO:1900063 | regulation of peroxisome organization(GO:1900063) |
| 0.0 | 0.1 | GO:0007412 | axon target recognition(GO:0007412) |
| 0.0 | 0.1 | GO:0048631 | regulation of skeletal muscle tissue growth(GO:0048631) |
| 0.0 | 0.1 | GO:0010430 | fatty acid omega-oxidation(GO:0010430) |
| 0.0 | 0.1 | GO:1902723 | negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) |
| 0.0 | 1.2 | GO:0071157 | negative regulation of cell cycle arrest(GO:0071157) |
| 0.0 | 0.3 | GO:0006880 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 0.0 | 4.5 | GO:0006342 | chromatin silencing(GO:0006342) |
| 0.0 | 0.3 | GO:0033141 | positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141) |
| 0.0 | 0.1 | GO:0044837 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
| 0.0 | 0.2 | GO:0031642 | negative regulation of myelination(GO:0031642) |
| 0.0 | 0.3 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
| 0.0 | 1.0 | GO:0002076 | osteoblast development(GO:0002076) |
| 0.0 | 1.6 | GO:0030890 | positive regulation of B cell proliferation(GO:0030890) |
| 0.0 | 0.2 | GO:0021943 | regulation of collagen catabolic process(GO:0010710) formation of radial glial scaffolds(GO:0021943) |
| 0.0 | 0.3 | GO:0046618 | drug export(GO:0046618) |
| 0.0 | 0.1 | GO:1903028 | positive regulation of opsonization(GO:1903028) |
| 0.0 | 0.2 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.0 | 0.6 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.0 | 0.3 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.0 | 0.3 | GO:0031125 | rRNA 3'-end processing(GO:0031125) |
| 0.0 | 0.2 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
| 0.0 | 5.5 | GO:0031638 | zymogen activation(GO:0031638) |
| 0.0 | 0.1 | GO:0019242 | methylglyoxal biosynthetic process(GO:0019242) |
| 0.0 | 0.2 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 0.0 | 0.1 | GO:1904647 | response to rotenone(GO:1904647) |
| 0.0 | 0.3 | GO:0006069 | ethanol oxidation(GO:0006069) |
| 0.0 | 1.1 | GO:0043403 | skeletal muscle tissue regeneration(GO:0043403) |
| 0.0 | 0.0 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) |
| 0.0 | 0.1 | GO:0044806 | G-quadruplex DNA unwinding(GO:0044806) |
| 0.0 | 0.3 | GO:2000628 | regulation of miRNA metabolic process(GO:2000628) |
| 0.0 | 0.1 | GO:2000547 | regulation of dendritic cell dendrite assembly(GO:2000547) |
| 0.0 | 0.2 | GO:1901843 | positive regulation of high voltage-gated calcium channel activity(GO:1901843) |
| 0.0 | 0.9 | GO:0060325 | face morphogenesis(GO:0060325) |
| 0.0 | 0.5 | GO:0061158 | 3'-UTR-mediated mRNA destabilization(GO:0061158) |
| 0.0 | 0.1 | GO:2000252 | negative regulation of feeding behavior(GO:2000252) |
| 0.0 | 0.1 | GO:0098886 | modification of dendritic spine(GO:0098886) |
| 0.0 | 0.4 | GO:0072257 | metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307) |
| 0.0 | 0.1 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
| 0.0 | 0.1 | GO:0060474 | positive regulation of sperm motility involved in capacitation(GO:0060474) |
| 0.0 | 0.1 | GO:0010760 | negative regulation of macrophage chemotaxis(GO:0010760) |
| 0.0 | 1.6 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.0 | 0.3 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 0.0 | 0.1 | GO:0060167 | regulation of adenosine receptor signaling pathway(GO:0060167) positive regulation of adenosine receptor signaling pathway(GO:0060168) |
| 0.0 | 0.2 | GO:0061525 | hindgut development(GO:0061525) |
| 0.0 | 0.4 | GO:1903071 | positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
| 0.0 | 0.9 | GO:0097120 | receptor localization to synapse(GO:0097120) |
| 0.0 | 0.1 | GO:0036072 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 0.0 | 0.3 | GO:2000821 | regulation of grooming behavior(GO:2000821) |
| 0.0 | 0.1 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
| 0.0 | 0.4 | GO:0019370 | leukotriene biosynthetic process(GO:0019370) |
| 0.0 | 0.1 | GO:0050917 | sensory perception of umami taste(GO:0050917) |
| 0.0 | 0.2 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.0 | 0.0 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
| 0.0 | 0.1 | GO:0070126 | mitochondrial translational termination(GO:0070126) |
| 0.0 | 0.0 | GO:0032672 | natural killer cell tolerance induction(GO:0002519) regulation of interleukin-3 production(GO:0032672) |
| 0.0 | 0.5 | GO:0070262 | peptidyl-serine dephosphorylation(GO:0070262) |
| 0.0 | 0.2 | GO:0055096 | lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) |
| 0.0 | 0.6 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
| 0.0 | 0.2 | GO:0060385 | axonogenesis involved in innervation(GO:0060385) |
| 0.0 | 0.4 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 0.0 | 0.4 | GO:1902895 | positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895) |
| 0.0 | 0.2 | GO:0097264 | self proteolysis(GO:0097264) |
| 0.0 | 0.7 | GO:0001893 | maternal placenta development(GO:0001893) |
| 0.0 | 0.1 | GO:0090245 | axis elongation involved in somitogenesis(GO:0090245) |
| 0.0 | 0.1 | GO:0006196 | AMP catabolic process(GO:0006196) |
| 0.0 | 0.1 | GO:0038155 | positive regulation of activation of Janus kinase activity(GO:0010536) interleukin-23-mediated signaling pathway(GO:0038155) |
| 0.0 | 0.1 | GO:0034154 | toll-like receptor 7 signaling pathway(GO:0034154) |
| 0.0 | 0.1 | GO:0021759 | globus pallidus development(GO:0021759) |
| 0.0 | 0.4 | GO:0009223 | pyrimidine deoxyribonucleotide catabolic process(GO:0009223) |
| 0.0 | 0.2 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 0.0 | 0.1 | GO:0019566 | arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373) |
| 0.0 | 0.3 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.0 | 0.0 | GO:0035378 | carbon dioxide transmembrane transport(GO:0035378) |
| 0.0 | 0.0 | GO:0035281 | pre-miRNA export from nucleus(GO:0035281) |
| 0.0 | 0.2 | GO:0030497 | fatty acid elongation(GO:0030497) |
| 0.0 | 0.1 | GO:0019303 | D-ribose catabolic process(GO:0019303) |
| 0.0 | 0.1 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 0.0 | 0.2 | GO:0001561 | fatty acid alpha-oxidation(GO:0001561) |
| 0.0 | 0.3 | GO:0071447 | cellular response to hydroperoxide(GO:0071447) |
| 0.0 | 0.2 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
| 0.0 | 0.1 | GO:0003322 | pancreatic A cell development(GO:0003322) |
| 0.0 | 0.3 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.0 | 0.2 | GO:0043568 | positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) |
| 0.0 | 1.1 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.0 | 0.3 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
| 0.0 | 0.1 | GO:0001714 | endodermal cell fate specification(GO:0001714) |
| 0.0 | 0.0 | GO:0030505 | inorganic diphosphate transport(GO:0030505) |
| 0.0 | 0.0 | GO:0014050 | negative regulation of glutamate secretion(GO:0014050) |
| 0.0 | 0.1 | GO:0035494 | SNARE complex disassembly(GO:0035494) |
| 0.0 | 0.2 | GO:0060272 | embryonic skeletal joint morphogenesis(GO:0060272) |
| 0.0 | 0.1 | GO:0048861 | leukemia inhibitory factor signaling pathway(GO:0048861) |
| 0.0 | 0.1 | GO:0030382 | sperm mitochondrion organization(GO:0030382) |
| 0.0 | 0.1 | GO:0071494 | cellular response to UV-C(GO:0071494) |
| 0.0 | 0.1 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.0 | 0.1 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.0 | 0.2 | GO:0015825 | L-serine transport(GO:0015825) |
| 0.0 | 0.0 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
| 0.0 | 0.1 | GO:0007171 | activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) |
| 0.0 | 0.2 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.0 | 0.2 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
| 0.0 | 0.0 | GO:0048539 | bone marrow development(GO:0048539) |
| 0.0 | 0.3 | GO:0010971 | positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) |
| 0.0 | 0.2 | GO:0006702 | androgen biosynthetic process(GO:0006702) |
| 0.0 | 0.1 | GO:0045078 | enucleate erythrocyte differentiation(GO:0043353) positive regulation of interferon-gamma biosynthetic process(GO:0045078) |
| 0.0 | 0.1 | GO:0021563 | glossopharyngeal nerve development(GO:0021563) |
| 0.0 | 0.2 | GO:0046600 | negative regulation of centriole replication(GO:0046600) |
| 0.0 | 0.5 | GO:1901661 | quinone metabolic process(GO:1901661) |
| 0.0 | 0.0 | GO:0042144 | vacuole fusion, non-autophagic(GO:0042144) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 5.2 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.3 | 3.3 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.3 | 3.1 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.3 | 4.2 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.2 | 3.4 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.2 | 0.6 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.2 | 1.8 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.2 | 3.7 | GO:0042627 | chylomicron(GO:0042627) |
| 0.1 | 0.6 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 0.1 | 9.4 | GO:0000786 | nucleosome(GO:0000786) |
| 0.1 | 1.2 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.1 | 1.1 | GO:0035976 | AP1 complex(GO:0035976) |
| 0.1 | 1.1 | GO:0036128 | CatSper complex(GO:0036128) |
| 0.1 | 0.3 | GO:0009346 | citrate lyase complex(GO:0009346) |
| 0.1 | 0.3 | GO:1903095 | microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095) |
| 0.1 | 0.6 | GO:0072589 | box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661) |
| 0.1 | 0.5 | GO:1990037 | Lewy body core(GO:1990037) |
| 0.1 | 1.0 | GO:0005583 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.1 | 0.2 | GO:0034677 | integrin alpha7-beta1 complex(GO:0034677) |
| 0.1 | 0.3 | GO:0030936 | collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936) |
| 0.1 | 0.5 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907) |
| 0.1 | 0.4 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 0.1 | 0.6 | GO:0000798 | nuclear cohesin complex(GO:0000798) |
| 0.0 | 0.2 | GO:0035354 | Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354) |
| 0.0 | 0.3 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 0.0 | 0.5 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.0 | 0.1 | GO:0097444 | spine apparatus(GO:0097444) |
| 0.0 | 0.8 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.0 | 0.3 | GO:1990357 | terminal web(GO:1990357) |
| 0.0 | 1.5 | GO:0000145 | exocyst(GO:0000145) |
| 0.0 | 0.6 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.0 | 0.1 | GO:0042585 | germinal vesicle(GO:0042585) |
| 0.0 | 0.3 | GO:0044326 | dendritic spine neck(GO:0044326) |
| 0.0 | 1.0 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 0.4 | GO:0014701 | junctional sarcoplasmic reticulum membrane(GO:0014701) |
| 0.0 | 0.1 | GO:1990923 | PET complex(GO:1990923) |
| 0.0 | 0.1 | GO:0031084 | BLOC-2 complex(GO:0031084) |
| 0.0 | 0.1 | GO:0005579 | membrane attack complex(GO:0005579) |
| 0.0 | 0.2 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 0.0 | 0.4 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.0 | 0.0 | GO:0070033 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) |
| 0.0 | 0.1 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
| 0.0 | 1.2 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 0.1 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 0.0 | 0.2 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
| 0.0 | 0.3 | GO:0098574 | cytoplasmic side of lysosomal membrane(GO:0098574) |
| 0.0 | 0.6 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.0 | 0.3 | GO:0032039 | integrator complex(GO:0032039) |
| 0.0 | 0.3 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.0 | 0.1 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 0.3 | GO:0072559 | NLRP3 inflammasome complex(GO:0072559) |
| 0.0 | 0.8 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 0.0 | 0.3 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.0 | 0.2 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.0 | 0.1 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
| 0.0 | 0.3 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.0 | 0.3 | GO:1990391 | DNA repair complex(GO:1990391) |
| 0.0 | 0.1 | GO:0072536 | interleukin-23 receptor complex(GO:0072536) |
| 0.0 | 2.1 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 0.2 | GO:0045275 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.0 | 0.1 | GO:0097179 | protease inhibitor complex(GO:0097179) |
| 0.0 | 0.1 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 0.0 | 0.1 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.0 | 0.0 | GO:0042565 | RNA nuclear export complex(GO:0042565) |
| 0.0 | 0.4 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.0 | 1.0 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.0 | 0.1 | GO:0060200 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
| 0.0 | 3.3 | GO:0030018 | Z disc(GO:0030018) |
| 0.0 | 0.1 | GO:0032009 | early phagosome(GO:0032009) |
| 0.0 | 0.6 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 0.2 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.0 | 1.1 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.0 | 0.3 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.0 | 0.6 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 0.2 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.0 | 0.1 | GO:0071546 | pi-body(GO:0071546) |
| 0.0 | 0.2 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.0 | 0.2 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.0 | 0.1 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.0 | 0.1 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.0 | 1.6 | GO:0000123 | histone acetyltransferase complex(GO:0000123) |
| 0.0 | 0.3 | GO:0032585 | multivesicular body membrane(GO:0032585) |
| 0.0 | 1.3 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 0.2 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 0.1 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 0.0 | 0.2 | GO:0097225 | sperm midpiece(GO:0097225) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 4.2 | GO:0033265 | acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265) |
| 0.9 | 3.6 | GO:0017129 | triglyceride binding(GO:0017129) |
| 0.6 | 1.7 | GO:0016964 | alpha-2 macroglobulin receptor activity(GO:0016964) |
| 0.2 | 1.0 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
| 0.2 | 1.7 | GO:0043426 | MRF binding(GO:0043426) |
| 0.2 | 0.5 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
| 0.2 | 0.5 | GO:0016781 | selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781) |
| 0.2 | 0.5 | GO:0035403 | histone kinase activity (H3-T6 specific)(GO:0035403) |
| 0.1 | 1.3 | GO:0004465 | lipoprotein lipase activity(GO:0004465) |
| 0.1 | 1.2 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.1 | 1.2 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
| 0.1 | 0.6 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
| 0.1 | 1.6 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.1 | 0.3 | GO:0015235 | cobalamin transporter activity(GO:0015235) |
| 0.1 | 0.3 | GO:0004342 | glucosamine-6-phosphate deaminase activity(GO:0004342) |
| 0.1 | 3.1 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.1 | 0.5 | GO:0004556 | alpha-amylase activity(GO:0004556) |
| 0.1 | 0.3 | GO:0003878 | ATP citrate synthase activity(GO:0003878) |
| 0.1 | 0.5 | GO:0004668 | protein-arginine deiminase activity(GO:0004668) |
| 0.1 | 0.3 | GO:0005503 | all-trans retinal binding(GO:0005503) |
| 0.1 | 1.2 | GO:0004445 | inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) |
| 0.1 | 0.3 | GO:0004464 | leukotriene-C4 synthase activity(GO:0004464) |
| 0.1 | 0.7 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
| 0.1 | 0.8 | GO:0001016 | RNA polymerase III regulatory region DNA binding(GO:0001016) thioredoxin peroxidase activity(GO:0008379) |
| 0.1 | 0.3 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) |
| 0.1 | 0.5 | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
| 0.1 | 0.2 | GO:0004170 | dUTP diphosphatase activity(GO:0004170) |
| 0.1 | 3.3 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.1 | 0.4 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
| 0.1 | 0.4 | GO:0004504 | peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598) |
| 0.1 | 1.6 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.1 | 0.2 | GO:0008160 | protein tyrosine phosphatase activator activity(GO:0008160) |
| 0.1 | 0.2 | GO:0004618 | phosphoglycerate kinase activity(GO:0004618) |
| 0.1 | 0.2 | GO:0097100 | supercoiled DNA binding(GO:0097100) |
| 0.1 | 2.3 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.1 | 0.2 | GO:0019166 | trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
| 0.1 | 0.1 | GO:0008240 | tripeptidyl-peptidase activity(GO:0008240) |
| 0.1 | 0.3 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.1 | 1.0 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.1 | 0.2 | GO:0042007 | interleukin-18 binding(GO:0042007) |
| 0.1 | 0.3 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
| 0.1 | 0.7 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.0 | 0.2 | GO:0016314 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314) phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800) |
| 0.0 | 0.5 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 0.0 | 0.3 | GO:0004525 | ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) |
| 0.0 | 0.6 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
| 0.0 | 0.3 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.0 | 0.3 | GO:0005132 | type I interferon receptor binding(GO:0005132) |
| 0.0 | 0.1 | GO:0019862 | IgA binding(GO:0019862) |
| 0.0 | 0.2 | GO:0004329 | formate-tetrahydrofolate ligase activity(GO:0004329) |
| 0.0 | 0.6 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.0 | 0.3 | GO:0015307 | drug:proton antiporter activity(GO:0015307) |
| 0.0 | 0.3 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 0.0 | 0.9 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.0 | 0.1 | GO:0033677 | single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677) |
| 0.0 | 0.3 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.0 | 0.1 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
| 0.0 | 0.2 | GO:0017099 | very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099) |
| 0.0 | 0.2 | GO:0004874 | aryl hydrocarbon receptor activity(GO:0004874) |
| 0.0 | 1.1 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.0 | 3.7 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.0 | 0.3 | GO:0003960 | NADPH:quinone reductase activity(GO:0003960) |
| 0.0 | 0.1 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
| 0.0 | 0.1 | GO:0071723 | lipopeptide binding(GO:0071723) |
| 0.0 | 0.2 | GO:0035529 | NADH pyrophosphatase activity(GO:0035529) |
| 0.0 | 0.1 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
| 0.0 | 0.5 | GO:0045159 | myosin II binding(GO:0045159) |
| 0.0 | 0.2 | GO:0047288 | monosialoganglioside sialyltransferase activity(GO:0047288) |
| 0.0 | 0.7 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 0.0 | 1.2 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
| 0.0 | 0.2 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
| 0.0 | 0.4 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.0 | 0.6 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
| 0.0 | 1.8 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.0 | 0.3 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.0 | 0.3 | GO:1990948 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
| 0.0 | 0.8 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 0.1 | GO:0016623 | aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) |
| 0.0 | 0.1 | GO:0004967 | glucagon receptor activity(GO:0004967) |
| 0.0 | 0.2 | GO:0023024 | MHC class I protein complex binding(GO:0023024) |
| 0.0 | 1.2 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.0 | 4.0 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.0 | 0.5 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 0.3 | GO:1901612 | cardiolipin binding(GO:1901612) |
| 0.0 | 0.1 | GO:0004347 | glucose-6-phosphate isomerase activity(GO:0004347) |
| 0.0 | 0.1 | GO:0000384 | first spliceosomal transesterification activity(GO:0000384) |
| 0.0 | 1.0 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.0 | 0.3 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.0 | 0.4 | GO:0019103 | pyrimidine nucleotide binding(GO:0019103) |
| 0.0 | 0.2 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
| 0.0 | 0.5 | GO:0005522 | profilin binding(GO:0005522) |
| 0.0 | 0.2 | GO:0004118 | cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) |
| 0.0 | 0.1 | GO:0047757 | chondroitin-glucuronate 5-epimerase activity(GO:0047757) |
| 0.0 | 0.1 | GO:0016822 | hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823) |
| 0.0 | 0.5 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 0.0 | 0.1 | GO:0047291 | neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291) |
| 0.0 | 0.2 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.0 | 0.4 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.0 | 0.1 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 0.0 | 0.1 | GO:0047057 | oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057) |
| 0.0 | 0.1 | GO:0047708 | biotinidase activity(GO:0047708) |
| 0.0 | 0.1 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 0.0 | 0.4 | GO:0031404 | chloride ion binding(GO:0031404) |
| 0.0 | 0.1 | GO:0055100 | adiponectin binding(GO:0055100) |
| 0.0 | 0.4 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 0.2 | GO:0035325 | Toll-like receptor binding(GO:0035325) |
| 0.0 | 0.1 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
| 0.0 | 0.1 | GO:0031735 | CCR10 chemokine receptor binding(GO:0031735) |
| 0.0 | 0.4 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.0 | 0.1 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
| 0.0 | 1.7 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 0.3 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 0.0 | 0.1 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 0.0 | 0.1 | GO:0016296 | oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297) |
| 0.0 | 0.1 | GO:0017060 | 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060) |
| 0.0 | 0.1 | GO:0042020 | interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020) |
| 0.0 | 0.6 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.0 | 0.1 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.0 | 0.1 | GO:0052642 | lysophosphatidic acid phosphatase activity(GO:0052642) |
| 0.0 | 3.2 | GO:0005178 | integrin binding(GO:0005178) |
| 0.0 | 0.8 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.0 | 0.1 | GO:0004923 | leukemia inhibitory factor receptor activity(GO:0004923) |
| 0.0 | 0.1 | GO:0003998 | acylphosphatase activity(GO:0003998) |
| 0.0 | 0.2 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.0 | 0.1 | GO:0046556 | alpha-L-arabinofuranosidase activity(GO:0046556) |
| 0.0 | 0.1 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.0 | 0.0 | GO:0035379 | carbon dioxide transmembrane transporter activity(GO:0035379) |
| 0.0 | 0.2 | GO:0000990 | transcription factor activity, core RNA polymerase binding(GO:0000990) |
| 0.0 | 0.1 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 0.0 | 0.2 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.0 | 0.1 | GO:0047961 | glycine N-acyltransferase activity(GO:0047961) |
| 0.0 | 0.2 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.0 | 0.1 | GO:0005483 | soluble NSF attachment protein activity(GO:0005483) |
| 0.0 | 0.0 | GO:0030984 | kininogen binding(GO:0030984) |
| 0.0 | 0.2 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.0 | 0.0 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988) |
| 0.0 | 0.0 | GO:0033858 | N-acetylgalactosamine kinase activity(GO:0033858) |
| 0.0 | 0.1 | GO:0004925 | prolactin receptor activity(GO:0004925) |
| 0.0 | 0.4 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.0 | 0.4 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.0 | 0.2 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.0 | 0.4 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.0 | 0.1 | GO:0047623 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.0 | 0.1 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) ER retention sequence binding(GO:0046923) |
| 0.0 | 0.2 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.0 | 0.1 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
| 0.0 | 0.3 | GO:0000339 | RNA cap binding(GO:0000339) |
| 0.0 | 0.4 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.0 | 2.6 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 0.5 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.0 | 0.2 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.0 | 0.2 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.6 | SA_CASPASE_CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.1 | 3.3 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 0.9 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.0 | 0.7 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 2.1 | NABA_COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 1.5 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 1.7 | PID_SYNDECAN_4_PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 1.3 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 0.4 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 1.4 | PID_RAS_PATHWAY | Regulation of Ras family activation |
| 0.0 | 1.6 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
| 0.0 | 0.8 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
| 0.0 | 0.6 | PID_REG_GR_PATHWAY | Glucocorticoid receptor regulatory network |
| 0.0 | 1.8 | PID_TGFBR_PATHWAY | TGF-beta receptor signaling |
| 0.0 | 2.0 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 0.4 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
| 0.0 | 0.5 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
| 0.0 | 4.1 | NABA_CORE_MATRISOME | Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans |
| 0.0 | 0.2 | PID_VEGF_VEGFR_PATHWAY | VEGF and VEGFR signaling network |
| 0.0 | 1.4 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 1.2 | PID_NFAT_3PATHWAY | Role of Calcineurin-dependent NFAT signaling in lymphocytes |
| 0.0 | 0.2 | PID_FGF_PATHWAY | FGF signaling pathway |
| 0.0 | 0.5 | PID_BARD1_PATHWAY | BARD1 signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.5 | REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.2 | 9.2 | REACTOME_PACKAGING_OF_TELOMERE_ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.1 | 3.6 | REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.1 | 2.8 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
| 0.1 | 3.3 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
| 0.1 | 1.3 | REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
| 0.0 | 1.1 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.0 | 1.0 | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.0 | 0.3 | REACTOME_BETA_DEFENSINS | Genes involved in Beta defensins |
| 0.0 | 2.0 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 0.6 | REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.0 | 1.4 | REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE | Genes involved in Formation of Fibrin Clot (Clotting Cascade) |
| 0.0 | 1.4 | REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.0 | 0.4 | REACTOME_ETHANOL_OXIDATION | Genes involved in Ethanol oxidation |
| 0.0 | 2.1 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 0.4 | REACTOME_PYRIMIDINE_CATABOLISM | Genes involved in Pyrimidine catabolism |
| 0.0 | 1.6 | REACTOME_MEIOTIC_SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.0 | 2.2 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
| 0.0 | 1.5 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 0.5 | REACTOME_AMYLOIDS | Genes involved in Amyloids |
| 0.0 | 0.9 | REACTOME_SIGNALING_BY_HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 0.8 | REACTOME_TELOMERE_MAINTENANCE | Genes involved in Telomere Maintenance |
| 0.0 | 0.2 | REACTOME_ANDROGEN_BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
| 0.0 | 0.7 | REACTOME_EGFR_DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.0 | 1.7 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
| 0.0 | 0.4 | REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.0 | 0.4 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.0 | 0.6 | REACTOME_GLUTATHIONE_CONJUGATION | Genes involved in Glutathione conjugation |
| 0.0 | 0.5 | REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.0 | 0.6 | REACTOME_ACTIVATION_OF_GENES_BY_ATF4 | Genes involved in Activation of Genes by ATF4 |
| 0.0 | 0.2 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.0 | 0.3 | REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
| 0.0 | 0.2 | REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.0 | 0.4 | REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.0 | 0.1 | REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 0.0 | 0.5 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 0.3 | REACTOME_SYNTHESIS_OF_PE | Genes involved in Synthesis of PE |
| 0.0 | 0.4 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 1.8 | REACTOME_PEPTIDE_CHAIN_ELONGATION | Genes involved in Peptide chain elongation |
| 0.0 | 0.2 | REACTOME_G_PROTEIN_ACTIVATION | Genes involved in G-protein activation |
| 0.0 | 0.2 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.0 | 0.3 | REACTOME_ENOS_ACTIVATION_AND_REGULATION | Genes involved in eNOS activation and regulation |
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