Motif ID: POU4F2

Z-value: 0.250


Transcription factors associated with POU4F2:

Gene SymbolEntrez IDGene Name
POU4F2 ENSG00000151615.3 POU4F2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
POU4F2hg19_v2_chr4_+_147560042_147560046-0.383.2e-01Click!


Activity profile for motif POU4F2.

activity profile for motif POU4F2


Sorted Z-values histogram for motif POU4F2

Sorted Z-values for motif POU4F2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU4F2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_151042224 0.296 ENST00000358517.2
 PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr6_-_111136513 0.232 ENST00000368911.3
 CDK19
cyclin-dependent kinase 19
chrX_-_99987088 0.229 ENST00000372981.1
ENST00000263033.5
 SYTL4

synaptotagmin-like 4

chr16_+_19422035 0.221 ENST00000381414.4
ENST00000396229.2
 TMC5

transmembrane channel-like 5

chr10_+_18549645 0.182 ENST00000396576.2
 CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr6_-_111136299 0.175 ENST00000457688.1
 CDK19
cyclin-dependent kinase 19
chr8_-_18541603 0.173 ENST00000428502.2
 PSD3
pleckstrin and Sec7 domain containing 3
chr16_+_19421803 0.169 ENST00000541464.1
 TMC5
transmembrane channel-like 5
chr15_+_101402041 0.151 ENST00000558475.1
ENST00000558641.1
ENST00000559673.1
 RP11-66B24.1


RP11-66B24.1


chr14_-_70883708 0.147 ENST00000256366.4
 SYNJ2BP
synaptojanin 2 binding protein
chr9_-_5830768 0.129 ENST00000381506.3
 ERMP1
endoplasmic reticulum metallopeptidase 1
chr15_-_43877062 0.128 ENST00000381885.1
ENST00000396923.3
 PPIP5K1

diphosphoinositol pentakisphosphate kinase 1

chrX_-_133931164 0.122 ENST00000370790.1
ENST00000298090.6
 FAM122B

family with sequence similarity 122B

chrX_+_133930798 0.121 ENST00000414371.2
 FAM122C
family with sequence similarity 122C
chr1_+_229440129 0.121 ENST00000366688.3
 SPHAR
S-phase response (cyclin related)
chr8_-_49834299 0.105 ENST00000396822.1
 SNAI2
snail family zinc finger 2
chr20_+_48909240 0.103 ENST00000371639.3
 RP11-290F20.1
RP11-290F20.1
chr16_+_28505955 0.102 ENST00000564831.1
ENST00000328423.5
ENST00000431282.1
 APOBR


apolipoprotein B receptor


chr8_-_49833978 0.099 ENST00000020945.1
 SNAI2
snail family zinc finger 2
chr14_-_90085458 0.099 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
 FOXN3


forkhead box N3


chr18_+_32455201 0.094 ENST00000590831.2
 DTNA
dystrobrevin, alpha
chr17_-_7832753 0.090 ENST00000303790.2
 KCNAB3
potassium voltage-gated channel, shaker-related subfamily, beta member 3
chr3_-_79816965 0.087 ENST00000464233.1
 ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr20_-_50419055 0.079 ENST00000217086.4
 SALL4
spalt-like transcription factor 4
chr11_-_115127611 0.077 ENST00000545094.1
 CADM1
cell adhesion molecule 1
chr17_-_33390667 0.077 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
 RFFL


ring finger and FYVE-like domain containing E3 ubiquitin protein ligase


chr4_+_144354644 0.072 ENST00000512843.1
 GAB1
GRB2-associated binding protein 1
chr17_+_73539339 0.069 ENST00000581713.1
 LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr2_+_44502597 0.069 ENST00000260649.6
ENST00000409387.1
 SLC3A1

solute carrier family 3 (amino acid transporter heavy chain), member 1

chr4_+_159443090 0.066 ENST00000343542.5
ENST00000470033.1
 RXFP1

relaxin/insulin-like family peptide receptor 1

chr19_+_1269324 0.065 ENST00000589710.1
ENST00000588230.1
ENST00000413636.2
ENST00000586472.1
ENST00000589686.1
ENST00000444172.2
ENST00000587323.1
ENST00000320936.5
ENST00000587896.1
ENST00000589235.1
ENST00000591659.1
 CIRBP










cold inducible RNA binding protein










chr17_+_61151306 0.065 ENST00000580068.1
ENST00000580466.1
 TANC2

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2

chr15_-_88247083 0.063 ENST00000560439.1
 RP11-648K4.2
RP11-648K4.2
chr6_-_74231444 0.062 ENST00000331523.2
ENST00000356303.2
 EEF1A1

eukaryotic translation elongation factor 1 alpha 1

chr5_+_102200948 0.062 ENST00000511477.1
ENST00000506006.1
ENST00000509832.1
 PAM


peptidylglycine alpha-amidating monooxygenase


chr17_+_48243352 0.061 ENST00000344627.6
ENST00000262018.3
ENST00000543315.1
ENST00000451235.2
ENST00000511303.1
 SGCA




sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)




chr4_+_159442878 0.058 ENST00000307765.5
ENST00000423548.1
 RXFP1

relaxin/insulin-like family peptide receptor 1

chr5_-_134914673 0.058 ENST00000512158.1
 CXCL14
chemokine (C-X-C motif) ligand 14
chr1_-_47655686 0.054 ENST00000294338.2
 PDZK1IP1
PDZK1 interacting protein 1
chr2_+_54951679 0.053 ENST00000356458.6
 EML6
echinoderm microtubule associated protein like 6
chr20_-_50418947 0.052 ENST00000371539.3
 SALL4
spalt-like transcription factor 4
chr13_+_46039037 0.051 ENST00000349995.5
 COG3
component of oligomeric golgi complex 3
chr20_-_50418972 0.048 ENST00000395997.3
 SALL4
spalt-like transcription factor 4
chr16_-_4852915 0.048 ENST00000322048.7
 ROGDI
rogdi homolog (Drosophila)
chr17_-_9929581 0.047 ENST00000437099.2
ENST00000396115.2
 GAS7

growth arrest-specific 7

chr16_+_89228757 0.046 ENST00000565008.1
 LINC00304
long intergenic non-protein coding RNA 304
chr11_-_31531121 0.046 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
 IMMP1L






IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)






chr6_-_111804905 0.043 ENST00000358835.3
ENST00000435970.1
 REV3L

REV3-like, polymerase (DNA directed), zeta, catalytic subunit

chr4_+_141264597 0.042 ENST00000338517.4
ENST00000394203.3
ENST00000506322.1
 SCOC


short coiled-coil protein


chr4_+_76481258 0.038 ENST00000311623.4
ENST00000435974.2
 C4orf26

chromosome 4 open reading frame 26

chr11_-_96076334 0.036 ENST00000524717.1
 MAML2
mastermind-like 2 (Drosophila)
chr12_+_56510368 0.033 ENST00000546591.1
ENST00000501597.3
 RPL41

ribosomal protein L41

chr4_+_159443024 0.032 ENST00000448688.2
 RXFP1
relaxin/insulin-like family peptide receptor 1
chr14_+_32030582 0.031 ENST00000550649.1
ENST00000281081.7
 NUBPL

nucleotide binding protein-like

chr11_+_73498898 0.031 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
 MRPL48





mitochondrial ribosomal protein L48





chr8_+_22857048 0.030 ENST00000251822.6
 RHOBTB2
Rho-related BTB domain containing 2
chr18_+_74240610 0.027 ENST00000578092.1
ENST00000578613.1
ENST00000583578.1
 LINC00908


long intergenic non-protein coding RNA 908


chr15_+_45544426 0.026 ENST00000347644.3
ENST00000560438.1
 SLC28A2

solute carrier family 28 (concentrative nucleoside transporter), member 2

chr10_+_95372289 0.025 ENST00000371447.3
 PDE6C
phosphodiesterase 6C, cGMP-specific, cone, alpha prime
chr4_-_10686475 0.024 ENST00000226951.6
 CLNK
cytokine-dependent hematopoietic cell linker
chr5_-_58295712 0.024 ENST00000317118.8
 PDE4D
phosphodiesterase 4D, cAMP-specific
chr18_-_73967160 0.023 ENST00000579714.1
 RP11-94B19.7
RP11-94B19.7
chr2_+_44502630 0.023 ENST00000410056.3
ENST00000409741.1
ENST00000409229.3
 SLC3A1


solute carrier family 3 (amino acid transporter heavy chain), member 1


chr6_+_118869452 0.021 ENST00000357525.5
 PLN
phospholamban
chr8_+_97773202 0.020 ENST00000519484.1
 CPQ
carboxypeptidase Q
chr14_+_23727694 0.018 ENST00000399905.1
ENST00000470456.1
 C14orf164

chromosome 14 open reading frame 164

chr8_+_97773457 0.016 ENST00000521142.1
 CPQ
carboxypeptidase Q
chr11_+_31531291 0.015 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
 ELP4


elongator acetyltransferase complex subunit 4


chr17_-_79623597 0.014 ENST00000574024.1
ENST00000331056.5
 PDE6G

phosphodiesterase 6G, cGMP-specific, rod, gamma

chr15_-_74421477 0.014 ENST00000514871.1
 RP11-247C2.2
HCG2004779; Uncharacterized protein
chr10_+_123951957 0.014 ENST00000514539.1
 TACC2
transforming, acidic coiled-coil containing protein 2
chr5_-_87516448 0.013 ENST00000511218.1
 TMEM161B
transmembrane protein 161B
chr10_-_116444371 0.013 ENST00000533213.2
ENST00000369252.4
 ABLIM1

actin binding LIM protein 1

chrX_+_139791917 0.013 ENST00000607004.1
ENST00000370535.3
 LINC00632

long intergenic non-protein coding RNA 632

chr21_+_17442799 0.013 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
 LINC00478


long intergenic non-protein coding RNA 478


chr14_+_97925151 0.012 ENST00000554862.1
ENST00000554260.1
ENST00000499910.2
 CTD-2506J14.1


CTD-2506J14.1


chr1_+_40506392 0.012 ENST00000414893.1
ENST00000414281.1
ENST00000420216.1
ENST00000372792.2
ENST00000372798.1
ENST00000340450.3
ENST00000372805.3
ENST00000435719.1
ENST00000427843.1
ENST00000417287.1
ENST00000424977.1
ENST00000446031.1
 CAP1











CAP, adenylate cyclase-associated protein 1 (yeast)











chr1_+_40506255 0.008 ENST00000421589.1
 CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr21_-_31874435 0.006 ENST00000334151.2
 KRTAP19-5
keratin associated protein 19-5
chr19_-_7697857 0.006 ENST00000598935.1
 PCP2
Purkinje cell protein 2
chr18_-_71959159 0.006 ENST00000494131.2
ENST00000397914.4
ENST00000340533.4
 CYB5A


cytochrome b5 type A (microsomal)


chr12_+_53848549 0.005 ENST00000439930.3
ENST00000548933.1
ENST00000562264.1
 PCBP2


poly(rC) binding protein 2


chr1_+_109265033 0.005 ENST00000445274.1
 FNDC7
fibronectin type III domain containing 7
chr19_-_10446449 0.004 ENST00000592439.1
 ICAM3
intercellular adhesion molecule 3
chr1_-_31666767 0.004 ENST00000530145.1
 NKAIN1
Na+/K+ transporting ATPase interacting 1
chr12_-_130529501 0.004 ENST00000567788.1
ENST00000561864.1
 RP11-474D1.3
RP11-474D1.4
RP11-474D1.3
RP11-474D1.4
chr3_+_50230105 0.003 ENST00000440836.1
 GNAT1
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
chr6_-_109777128 0.003 ENST00000358807.3
ENST00000358577.3
 MICAL1

microtubule associated monooxygenase, calponin and LIM domain containing 1

chr20_+_56136136 0.003 ENST00000319441.4
ENST00000543666.1
 PCK1

phosphoenolpyruvate carboxykinase 1 (soluble)

chr6_+_130339710 0.003 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
 L3MBTL3


l(3)mbt-like 3 (Drosophila)


chr14_+_42077552 0.002 ENST00000554120.1
 LRFN5
leucine rich repeat and fibronectin type III domain containing 5
chr13_-_74993252 0.001 ENST00000325811.1
 AL355390.1
Uncharacterized protein
chrX_+_3189861 0.001 ENST00000457435.1
ENST00000420429.2
 CXorf28

chromosome X open reading frame 28

chr10_-_99205607 0.001 ENST00000477692.2
ENST00000485122.2
ENST00000370886.5
ENST00000370885.4
ENST00000370902.3
ENST00000370884.5
 EXOSC1





exosome component 1





chr2_-_122262593 0.000 ENST00000418989.1
 CLASP1
cytoplasmic linker associated protein 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.2 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of high voltage-gated calcium channel activity(GO:1901843) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.1 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.0 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)