Motif ID: POU2F2_POU3F1

Z-value: 1.642

Transcription factors associated with POU2F2_POU3F1:

Gene SymbolEntrez IDGene Name
POU2F2 ENSG00000028277.16 POU2F2
POU3F1 ENSG00000185668.5 POU3F1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
POU2F2hg19_v2_chr19_-_42636617_42636632-0.521.5e-01Click!
POU3F1hg19_v2_chr1_-_38512450_38512474-0.176.6e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of POU2F2_POU3F1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_19796381 9.279 ENST00000524029.1
ENST00000522701.1
ENST00000311322.8
LPL


lipoprotein lipase


chr3_+_151591422 5.638 ENST00000362032.5
SUCNR1
succinate receptor 1
chr6_+_26124373 4.117 ENST00000377791.2
ENST00000602637.1
HIST1H2AC

histone cluster 1, H2ac

chr3_-_165555200 3.184 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE



butyrylcholinesterase



chr6_-_26124138 3.029 ENST00000314332.5
ENST00000396984.1
HIST1H2BC

histone cluster 1, H2bc

chr14_+_65007177 2.806 ENST00000247207.6
HSPA2
heat shock 70kDa protein 2
chrX_+_80457442 2.404 ENST00000373212.5
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr1_-_149858227 2.239 ENST00000369155.2
HIST2H2BE
histone cluster 2, H2be
chr6_-_27100529 2.196 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
HIST1H2BJ


histone cluster 1, H2bj


chr11_-_568369 2.181 ENST00000534540.1
ENST00000528245.1
ENST00000500447.1
ENST00000533920.1
MIR210HG



MIR210 host gene (non-protein coding)



chr16_+_2198604 2.158 ENST00000210187.6
RAB26
RAB26, member RAS oncogene family
chr16_-_30107491 2.083 ENST00000566134.1
ENST00000565110.1
ENST00000398841.1
ENST00000398838.4
YPEL3



yippee-like 3 (Drosophila)



chr1_+_149822620 2.023 ENST00000369159.2
HIST2H2AA4
histone cluster 2, H2aa4
chr6_-_26216872 1.867 ENST00000244601.3
HIST1H2BG
histone cluster 1, H2bg
chr6_+_26183958 1.839 ENST00000356530.3
HIST1H2BE
histone cluster 1, H2be
chr6_+_26217159 1.823 ENST00000303910.2
HIST1H2AE
histone cluster 1, H2ae
chr20_+_33292068 1.802 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
TP53INP2


tumor protein p53 inducible nuclear protein 2


chr19_-_50143452 1.750 ENST00000246792.3
RRAS
related RAS viral (r-ras) oncogene homolog
chr6_+_27100811 1.749 ENST00000359193.2
HIST1H2AG
histone cluster 1, H2ag
chr1_-_228645556 1.726 ENST00000366695.2
HIST3H2A
histone cluster 3, H2a
chr1_-_149814478 1.716 ENST00000369161.3
HIST2H2AA3
histone cluster 2, H2aa3
chr6_+_27861190 1.398 ENST00000303806.4
HIST1H2BO
histone cluster 1, H2bo
chr6_-_27860956 1.391 ENST00000359611.2
HIST1H2AM
histone cluster 1, H2am
chr14_-_34420259 1.351 ENST00000250457.3
ENST00000547327.2
EGLN3

egl-9 family hypoxia-inducible factor 3

chr11_-_94964354 1.350 ENST00000536441.1
SESN3
sestrin 3
chr19_-_44123734 1.280 ENST00000598676.1
ZNF428
zinc finger protein 428
chr19_-_44124019 1.278 ENST00000300811.3
ZNF428
zinc finger protein 428
chr14_+_103573853 1.208 ENST00000560304.1
EXOC3L4
exocyst complex component 3-like 4
chr6_+_37137939 1.170 ENST00000373509.5
PIM1
pim-1 oncogene
chr11_-_94964210 1.169 ENST00000416495.2
ENST00000393234.1
SESN3

sestrin 3

chrX_-_106960285 1.143 ENST00000503515.1
ENST00000372397.2
TSC22D3

TSC22 domain family, member 3

chr2_-_183291741 1.105 ENST00000351439.5
ENST00000409365.1
PDE1A

phosphodiesterase 1A, calmodulin-dependent

chr9_-_140196703 1.098 ENST00000356628.2
NRARP
NOTCH-regulated ankyrin repeat protein
chr6_-_27114577 1.080 ENST00000356950.1
ENST00000396891.4
HIST1H2BK

histone cluster 1, H2bk

chr11_+_110225855 1.048 ENST00000526605.1
ENST00000526703.1
RP11-347E10.1

RP11-347E10.1

chr12_+_72080253 1.015 ENST00000549735.1
TMEM19
transmembrane protein 19
chr1_+_149858461 0.945 ENST00000331380.2
HIST2H2AC
histone cluster 2, H2ac
chrX_-_80457385 0.939 ENST00000451455.1
ENST00000436386.1
ENST00000358130.2
HMGN5


high mobility group nucleosome binding domain 5


chr7_+_16793160 0.918 ENST00000262067.4
TSPAN13
tetraspanin 13
chr19_-_18392422 0.893 ENST00000252818.3
JUND
jun D proto-oncogene
chrX_-_131547625 0.829 ENST00000394311.2
MBNL3
muscleblind-like splicing regulator 3
chr6_+_26158343 0.811 ENST00000377777.4
ENST00000289316.2
HIST1H2BD

histone cluster 1, H2bd

chr6_+_26251835 0.790 ENST00000356350.2
HIST1H2BH
histone cluster 1, H2bh
chr12_-_7245125 0.789 ENST00000542285.1
ENST00000540610.1
C1R

complement component 1, r subcomponent

chr17_+_43213004 0.788 ENST00000586346.1
ENST00000398322.3
ENST00000592162.1
ENST00000376955.4
ENST00000321854.8
ACBD4




acyl-CoA binding domain containing 4




chr6_-_82462425 0.769 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A


family with sequence similarity 46, member A


chr1_+_201979645 0.767 ENST00000367284.5
ENST00000367283.3
ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

chr1_+_61547894 0.748 ENST00000403491.3
NFIA
nuclear factor I/A
chr2_+_241938255 0.747 ENST00000401884.1
ENST00000405547.3
ENST00000310397.8
ENST00000342631.6
SNED1



sushi, nidogen and EGF-like domains 1



chr12_-_7245080 0.737 ENST00000541042.1
ENST00000540242.1
C1R

complement component 1, r subcomponent

chr4_-_186733363 0.721 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2


sorbin and SH3 domain containing 2


chr13_-_52027134 0.710 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6




integrator complex subunit 6




chr3_+_197464046 0.701 ENST00000428738.1
FYTTD1
forty-two-three domain containing 1
chr19_+_11466167 0.692 ENST00000591608.1
DKFZP761J1410
Lipid phosphate phosphatase-related protein type 2
chr1_+_228645796 0.682 ENST00000369160.2
HIST3H2BB
histone cluster 3, H2bb
chr12_+_51317788 0.678 ENST00000550502.1
METTL7A
methyltransferase like 7A
chr1_+_201979743 0.675 ENST00000446188.1
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr17_+_62461569 0.666 ENST00000603557.1
ENST00000605096.1
MILR1

mast cell immunoglobulin-like receptor 1

chr2_-_2334888 0.665 ENST00000428368.2
ENST00000399161.2
MYT1L

myelin transcription factor 1-like

chr11_-_2906979 0.659 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
CDKN1C




cyclin-dependent kinase inhibitor 1C (p57, Kip2)




chr19_-_17516449 0.642 ENST00000252593.6
BST2
bone marrow stromal cell antigen 2
chr19_+_11466062 0.626 ENST00000251473.5
ENST00000591329.1
ENST00000586380.1
DKFZP761J1410


Lipid phosphate phosphatase-related protein type 2


chr12_-_7245018 0.621 ENST00000543835.1
ENST00000535233.2
C1R

complement component 1, r subcomponent

chr7_+_26438187 0.617 ENST00000439120.1
ENST00000430548.1
ENST00000421862.1
ENST00000449537.1
ENST00000420774.1
ENST00000418758.2
AC004540.5





AC004540.5





chr17_-_37382105 0.599 ENST00000333461.5
STAC2
SH3 and cysteine rich domain 2
chr6_-_33679452 0.593 ENST00000374231.4
ENST00000607484.1
ENST00000374214.3
UQCC2


ubiquinol-cytochrome c reductase complex assembly factor 2


chr22_-_24096630 0.569 ENST00000248948.3
VPREB3
pre-B lymphocyte 3
chr12_-_7245152 0.557 ENST00000542220.2
C1R
complement component 1, r subcomponent
chr4_-_187517928 0.556 ENST00000512772.1
FAT1
FAT atypical cadherin 1
chr6_-_149806105 0.555 ENST00000389942.5
ENST00000416573.2
ENST00000542614.1
ENST00000409806.3
ZC3H12D



zinc finger CCCH-type containing 12D



chr2_+_174219548 0.540 ENST00000347703.3
ENST00000392567.2
ENST00000306721.3
ENST00000410101.3
ENST00000410019.3
CDCA7




cell division cycle associated 7




chrX_-_117119243 0.524 ENST00000539496.1
ENST00000469946.1
KLHL13

kelch-like family member 13

chr22_+_44319648 0.516 ENST00000423180.2
PNPLA3
patatin-like phospholipase domain containing 3
chr22_+_44319619 0.513 ENST00000216180.3
PNPLA3
patatin-like phospholipase domain containing 3
chr9_-_35658007 0.496 ENST00000602361.1
RMRP
RNA component of mitochondrial RNA processing endoribonuclease
chr19_+_3572758 0.488 ENST00000416526.1
HMG20B
high mobility group 20B
chr4_+_184826418 0.480 ENST00000308497.4
ENST00000438269.1
STOX2

storkhead box 2

chr15_-_41166414 0.470 ENST00000220507.4
RHOV
ras homolog family member V
chr1_+_24018269 0.466 ENST00000374550.3
RPL11
ribosomal protein L11
chr1_-_149783914 0.460 ENST00000369167.1
ENST00000427880.2
ENST00000545683.1
HIST2H2BF


histone cluster 2, H2bf


chr11_-_3663502 0.457 ENST00000359918.4
ART5
ADP-ribosyltransferase 5
chr6_+_27775899 0.456 ENST00000358739.3
HIST1H2AI
histone cluster 1, H2ai
chr3_-_48594248 0.451 ENST00000545984.1
ENST00000232375.3
ENST00000416568.1
ENST00000383734.2
ENST00000541519.1
ENST00000412035.1
PFKFB4





6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4





chr18_+_32290218 0.445 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
DTNA


dystrobrevin, alpha


chr11_-_3663480 0.440 ENST00000397068.3
ART5
ADP-ribosyltransferase 5
chr6_-_10415470 0.433 ENST00000379604.2
ENST00000379613.3
TFAP2A

transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)

chr21_+_39493560 0.432 ENST00000400477.3
ENST00000357704.4
DSCR8

Down syndrome critical region gene 8

chr22_-_24096562 0.430 ENST00000398465.3
VPREB3
pre-B lymphocyte 3
chr4_+_124320665 0.423 ENST00000394339.2
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr11_-_27494309 0.403 ENST00000389858.4
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr5_-_175965008 0.396 ENST00000537487.1
RNF44
ring finger protein 44
chr4_-_44728530 0.393 ENST00000507534.1
GNPDA2
glucosamine-6-phosphate deaminase 2
chr4_-_44728559 0.393 ENST00000509756.1
ENST00000507917.1
ENST00000295448.3
GNPDA2


glucosamine-6-phosphate deaminase 2


chr11_-_27494279 0.391 ENST00000379214.4
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr19_+_17337406 0.383 ENST00000597836.1
OCEL1
occludin/ELL domain containing 1
chr19_+_17337473 0.379 ENST00000598068.1
OCEL1
occludin/ELL domain containing 1
chr16_-_54962415 0.370 ENST00000501177.3
ENST00000559598.2
CRNDE

colorectal neoplasia differentially expressed (non-protein coding)

chr12_+_49297899 0.361 ENST00000552942.1
ENST00000320516.4
CCDC65

coiled-coil domain containing 65

chr19_+_17337007 0.358 ENST00000215061.4
OCEL1
occludin/ELL domain containing 1
chr17_-_7580752 0.354 ENST00000508793.1
TP53
tumor protein p53
chr17_-_46682321 0.353 ENST00000225648.3
ENST00000484302.2
HOXB6

homeobox B6

chr5_-_39462390 0.348 ENST00000511792.1
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr17_+_38219063 0.345 ENST00000584985.1
ENST00000264637.4
ENST00000450525.2
THRA


thyroid hormone receptor, alpha


chr12_+_49297887 0.344 ENST00000266984.5
CCDC65
coiled-coil domain containing 65
chr1_-_149859466 0.343 ENST00000331128.3
HIST2H2AB
histone cluster 2, H2ab
chr2_-_211036051 0.343 ENST00000418791.1
ENST00000452086.1
ENST00000281772.9
KANSL1L


KAT8 regulatory NSL complex subunit 1-like


chr12_-_11175219 0.340 ENST00000390673.2
TAS2R19
taste receptor, type 2, member 19
chr18_-_6929797 0.339 ENST00000581725.1
ENST00000583316.1
LINC00668

long intergenic non-protein coding RNA 668

chr17_-_7307358 0.337 ENST00000535512.1
ENST00000576017.1
ENST00000302422.3
TMEM256-PLSCR3
TMEM256

TMEM256-PLSCR3 readthrough (NMD candidate)
transmembrane protein 256

chr12_+_14927270 0.329 ENST00000544848.1
H2AFJ
H2A histone family, member J
chr1_+_17575584 0.326 ENST00000375460.3
PADI3
peptidyl arginine deiminase, type III
chr1_-_68962805 0.325 ENST00000370966.5
DEPDC1
DEP domain containing 1
chr11_-_115375107 0.320 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1





cell adhesion molecule 1





chr12_-_100656134 0.318 ENST00000548313.1
DEPDC4
DEP domain containing 4
chr16_+_56969284 0.314 ENST00000568358.1
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr1_-_6052463 0.311 ENST00000378156.4
NPHP4
nephronophthisis 4
chrX_+_12993202 0.310 ENST00000451311.2
ENST00000380636.1
TMSB4X

thymosin beta 4, X-linked

chr19_+_17337027 0.308 ENST00000601529.1
ENST00000600232.1
OCEL1

occludin/ELL domain containing 1

chr1_-_68962782 0.308 ENST00000456315.2
DEPDC1
DEP domain containing 1
chr1_+_28099700 0.308 ENST00000440806.2
STX12
syntaxin 12
chr19_+_56111680 0.304 ENST00000301073.3
ZNF524
zinc finger protein 524
chr1_-_23886285 0.304 ENST00000374561.5
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr19_+_3572925 0.302 ENST00000333651.6
ENST00000417382.1
ENST00000453933.1
ENST00000262949.7
HMG20B



high mobility group 20B



chr19_-_19144243 0.301 ENST00000594445.1
ENST00000452918.2
ENST00000600377.1
ENST00000337018.6
SUGP2



SURP and G patch domain containing 2



chr17_+_27369918 0.300 ENST00000323372.4
PIPOX
pipecolic acid oxidase
chr2_-_172750733 0.299 ENST00000392592.4
ENST00000422440.2
SLC25A12

solute carrier family 25 (aspartate/glutamate carrier), member 12

chr19_+_1269324 0.296 ENST00000589710.1
ENST00000588230.1
ENST00000413636.2
ENST00000586472.1
ENST00000589686.1
ENST00000444172.2
ENST00000587323.1
ENST00000320936.5
ENST00000587896.1
ENST00000589235.1
ENST00000591659.1
CIRBP










cold inducible RNA binding protein










chr17_+_73521763 0.293 ENST00000167462.5
ENST00000375227.4
ENST00000392550.3
ENST00000578363.1
ENST00000579392.1
LLGL2




lethal giant larvae homolog 2 (Drosophila)




chr1_+_206730484 0.291 ENST00000304534.8
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr20_-_60982330 0.291 ENST00000279101.5
CABLES2
Cdk5 and Abl enzyme substrate 2
chr19_-_8373173 0.285 ENST00000537716.2
ENST00000301458.5
CD320

CD320 molecule

chr4_-_18023350 0.280 ENST00000539056.1
ENST00000382226.5
ENST00000326877.4
LCORL


ligand dependent nuclear receptor corepressor-like


chr5_-_81574160 0.277 ENST00000510210.1
ENST00000512493.1
ENST00000507980.1
ENST00000511844.1
ENST00000510019.1
RPS23




ribosomal protein S23




chr1_+_32666188 0.274 ENST00000421922.2
CCDC28B
coiled-coil domain containing 28B
chr9_-_124991124 0.268 ENST00000394319.4
ENST00000340587.3
LHX6

LIM homeobox 6

chr10_-_81205373 0.265 ENST00000372336.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr17_-_7832753 0.265 ENST00000303790.2
KCNAB3
potassium voltage-gated channel, shaker-related subfamily, beta member 3
chr1_-_110284384 0.263 ENST00000540225.1
GSTM3
glutathione S-transferase mu 3 (brain)
chr6_+_27782788 0.262 ENST00000359465.4
HIST1H2BM
histone cluster 1, H2bm
chr12_+_124997766 0.260 ENST00000543970.1
RP11-83B20.1
RP11-83B20.1
chr11_+_74699703 0.256 ENST00000529024.1
ENST00000544263.1
NEU3

sialidase 3 (membrane sialidase)

chr7_-_73038822 0.256 ENST00000414749.2
ENST00000429400.2
ENST00000434326.1
MLXIPL


MLX interacting protein-like


chr11_+_64085560 0.255 ENST00000265462.4
ENST00000352435.4
ENST00000347941.4
PRDX5


peroxiredoxin 5


chr6_-_74231444 0.254 ENST00000331523.2
ENST00000356303.2
EEF1A1

eukaryotic translation elongation factor 1 alpha 1

chr17_+_20059302 0.252 ENST00000395530.2
SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr1_+_104198377 0.249 ENST00000370083.4
AMY1A
amylase, alpha 1A (salivary)
chr15_-_64995399 0.246 ENST00000559753.1
ENST00000560258.2
ENST00000559912.2
ENST00000326005.6
OAZ2



ornithine decarboxylase antizyme 2



chr12_-_31479045 0.245 ENST00000539409.1
ENST00000395766.1
FAM60A

family with sequence similarity 60, member A

chr16_-_89008211 0.245 ENST00000569464.1
ENST00000569443.1
CBFA2T3

core-binding factor, runt domain, alpha subunit 2; translocated to, 3

chr18_-_47017956 0.244 ENST00000584895.1
ENST00000332968.6
ENST00000580210.1
ENST00000579408.1
RPL17-C18orf32

RPL17

RPL17-C18orf32 readthrough

ribosomal protein L17

chr7_-_130080977 0.240 ENST00000223208.5
CEP41
centrosomal protein 41kDa
chr5_+_159895275 0.239 ENST00000517927.1
MIR146A
microRNA 146a
chr8_+_102064237 0.238 ENST00000514926.1
RP11-302J23.1
RP11-302J23.1
chr19_+_14444525 0.237 ENST00000588275.1
CTC-548K16.1
CTC-548K16.1
chr11_-_75917569 0.237 ENST00000322563.3
WNT11
wingless-type MMTV integration site family, member 11
chr4_-_40517984 0.234 ENST00000381795.6
RBM47
RNA binding motif protein 47
chr11_+_74699942 0.234 ENST00000526068.1
ENST00000532963.1
ENST00000531619.1
ENST00000534628.1
ENST00000545272.1
NEU3




sialidase 3 (membrane sialidase)




chr2_+_54785485 0.233 ENST00000333896.5
SPTBN1
spectrin, beta, non-erythrocytic 1
chr1_-_68962744 0.232 ENST00000525124.1
DEPDC1
DEP domain containing 1
chr5_-_179045199 0.229 ENST00000523921.1
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr1_-_190446759 0.228 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr4_-_110223799 0.221 ENST00000399132.1
ENST00000399126.1
ENST00000505591.1
COL25A1


collagen, type XXV, alpha 1


chr17_-_47841485 0.219 ENST00000506156.1
ENST00000240364.2
FAM117A

family with sequence similarity 117, member A

chr17_+_80858418 0.217 ENST00000574422.1
TBCD
tubulin folding cofactor D
chr18_-_45457478 0.214 ENST00000402690.2
ENST00000356825.4
SMAD2

SMAD family member 2

chr12_-_31479107 0.212 ENST00000542983.1
FAM60A
family with sequence similarity 60, member A
chr1_+_6052700 0.211 ENST00000378092.1
ENST00000445501.1
KCNAB2

potassium voltage-gated channel, shaker-related subfamily, beta member 2

chr11_+_112047087 0.211 ENST00000526088.1
ENST00000532593.1
ENST00000531169.1
BCO2


beta-carotene oxygenase 2


chr12_-_94673956 0.210 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr2_-_61108449 0.210 ENST00000439412.1
ENST00000452343.1
AC010733.4

AC010733.4

chr10_+_111765562 0.209 ENST00000360162.3
ADD3
adducin 3 (gamma)
chr7_-_73038867 0.208 ENST00000313375.3
ENST00000354613.1
ENST00000395189.1
ENST00000453275.1
MLXIPL



MLX interacting protein-like



chr22_-_22221900 0.207 ENST00000215832.6
ENST00000398822.3
MAPK1

mitogen-activated protein kinase 1

chr20_+_55204351 0.205 ENST00000201031.2
TFAP2C
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr15_-_58357866 0.204 ENST00000537372.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr3_+_187957646 0.203 ENST00000457242.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr2_+_58134756 0.203 ENST00000435505.2
ENST00000417641.2
VRK2

vaccinia related kinase 2

chr17_-_19651668 0.202 ENST00000494157.2
ENST00000225740.6
ALDH3A1

aldehyde dehydrogenase 3 family, member A1

chr3_+_156008809 0.202 ENST00000302490.8
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr1_+_210406121 0.199 ENST00000367012.3
SERTAD4
SERTA domain containing 4
chr7_+_116451100 0.198 ENST00000464223.1
ENST00000484325.1
CAPZA2

capping protein (actin filament) muscle Z-line, alpha 2

chr17_+_63096903 0.194 ENST00000582940.1
RP11-160O5.1
RP11-160O5.1
chr3_-_24207039 0.193 ENST00000280696.5
THRB
thyroid hormone receptor, beta
chr12_-_50616382 0.192 ENST00000552783.1
LIMA1
LIM domain and actin binding 1
chr15_-_58357932 0.191 ENST00000347587.3
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr2_+_42721689 0.186 ENST00000405592.1
MTA3
metastasis associated 1 family, member 3
chr5_+_158527485 0.183 ENST00000517335.1
RP11-175K6.1
RP11-175K6.1
chr12_+_54366894 0.180 ENST00000546378.1
ENST00000243082.4
HOXC11

homeobox C11

chr2_-_175462934 0.179 ENST00000392546.2
ENST00000436221.1
WIPF1

WAS/WASL interacting protein family, member 1

chr7_-_130080818 0.178 ENST00000343969.5
ENST00000541543.1
ENST00000489512.1
CEP41


centrosomal protein 41kDa


chr6_-_35656685 0.178 ENST00000539068.1
ENST00000540787.1
FKBP5

FK506 binding protein 5

chr6_+_122720681 0.175 ENST00000368455.4
ENST00000452194.1
HSF2

heat shock transcription factor 2

chr12_+_19358228 0.174 ENST00000424268.1
ENST00000543806.1
PLEKHA5

pleckstrin homology domain containing, family A member 5

chr6_+_41010293 0.174 ENST00000373161.1
ENST00000373158.2
ENST00000470917.1
TSPO2


translocator protein 2


chr2_-_158182105 0.173 ENST00000409925.1
ERMN
ermin, ERM-like protein
chr17_-_56494882 0.172 ENST00000584437.1
RNF43
ring finger protein 43
chr1_-_117021430 0.172 ENST00000423907.1
ENST00000434879.1
ENST00000443219.1
RP4-655J12.4


RP4-655J12.4


chr6_-_99797522 0.170 ENST00000389677.5
FAXC
failed axon connections homolog (Drosophila)
chr8_-_117886612 0.169 ENST00000520992.1
RAD21
RAD21 homolog (S. pombe)
chr6_+_148663729 0.169 ENST00000367467.3
SASH1
SAM and SH3 domain containing 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 9.3 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890) chylomicron remodeling(GO:0034371)
0.6 8.5 GO:0002227 innate immune response in mucosa(GO:0002227)
0.4 3.2 GO:0009820 alkaloid metabolic process(GO:0009820)
0.3 0.8 GO:0006043 glucosamine catabolic process(GO:0006043)
0.2 0.6 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731)
0.2 0.8 GO:0061289 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.2 1.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.2 2.5 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 3.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 1.1 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.5 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.1 0.6 GO:0003409 optic cup structural organization(GO:0003409)
0.1 0.5 GO:0008050 female courtship behavior(GO:0008050)
0.1 1.2 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.1 0.4 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.1 0.2 GO:0042214 terpene metabolic process(GO:0042214)
0.1 0.3 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 1.7 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 1.4 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.4 GO:0097252 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.1 10.9 GO:0006342 chromatin silencing(GO:0006342)
0.1 0.2 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1 0.4 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 1.0 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.1 0.3 GO:0031296 B cell costimulation(GO:0031296)
0.1 0.2 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 0.4 GO:0035799 ureter maturation(GO:0035799)
0.1 0.3 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.8 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.1 0.3 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.4 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 1.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.2 GO:0051601 exocyst localization(GO:0051601)
0.1 0.3 GO:0046440 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.1 0.6 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.3 GO:0035026 leading edge cell differentiation(GO:0035026)
0.1 0.7 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.1 0.4 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.1 0.3 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 0.7 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.1 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.0 0.8 GO:0072189 ureter development(GO:0072189)
0.0 1.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0072179 nephric duct formation(GO:0072179)
0.0 0.2 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 1.7 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.3 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.1 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.0 0.5 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.2 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.5 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.7 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 2.2 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.8 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 4.2 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.3 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.1 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.0 1.0 GO:0002076 osteoblast development(GO:0002076)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.6 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.3 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.2 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.1 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.5 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.2 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.3 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.3 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:0048867 ganglion mother cell fate determination(GO:0007402) stem cell fate determination(GO:0048867)
0.0 1.7 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.2 GO:0060539 diaphragm development(GO:0060539)
0.0 0.3 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.1 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.0 0.2 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.0 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.0 0.7 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 1.8 GO:0000045 autophagosome assembly(GO:0000045)
0.0 0.6 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.3 GO:0018126 protein hydroxylation(GO:0018126)
0.0 0.1 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.5 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.2 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.0 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.3 GO:0042627 chylomicron(GO:0042627)
0.4 23.6 GO:0000786 nucleosome(GO:0000786)
0.3 2.8 GO:0036128 CatSper complex(GO:0036128)
0.2 3.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 2.5 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.9 GO:0035976 AP1 complex(GO:0035976)
0.1 0.3 GO:1990037 Lewy body core(GO:1990037)
0.0 0.7 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.7 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.3 GO:0000798 nuclear cohesin complex(GO:0000798)
0.0 0.2 GO:0032437 cuticular plate(GO:0032437)
0.0 1.2 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 1.8 GO:0005811 lipid particle(GO:0005811)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 9.3 GO:0017129 triglyceride binding(GO:0017129)
0.8 3.2 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.3 0.8 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.2 1.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.9 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 1.1 GO:0043426 MRF binding(GO:0043426)
0.1 0.9 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.3 GO:0015235 cobalamin transporter activity(GO:0015235)
0.1 0.3 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.5 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 0.4 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 1.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 2.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.3 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.2 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.5 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.4 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.1 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.0 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.7 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.2 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 0.9 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.5 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 0.3 GO:0001016 RNA polymerase III regulatory region DNA binding(GO:0001016)
0.0 0.4 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.8 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 20.5 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 1.7 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.3 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 3.1 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.2 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.0 0.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
0.0 0.3 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 1.0 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.1 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 0.5 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 26.4 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.4 9.3 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 3.2 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.7 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 2.8 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.2 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.2 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.7 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.7 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.3 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.3 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 0.4 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.5 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo