Motif ID: PKNOX2

Z-value: 0.573


Transcription factors associated with PKNOX2:

Gene SymbolEntrez IDGene Name
PKNOX2 ENSG00000165495.11 PKNOX2



Activity profile for motif PKNOX2.

activity profile for motif PKNOX2


Sorted Z-values histogram for motif PKNOX2

Sorted Z-values for motif PKNOX2



Network of associatons between targets according to the STRING database.



First level regulatory network of PKNOX2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_26124373 0.376 ENST00000377791.2
ENST00000602637.1
HIST1H2AC

histone cluster 1, H2ac

chr5_-_94620239 0.355 ENST00000515393.1
MCTP1
multiple C2 domains, transmembrane 1
chr6_-_101329157 0.338 ENST00000369143.2
ASCC3
activating signal cointegrator 1 complex subunit 3
chr6_+_138188551 0.306 ENST00000237289.4
ENST00000433680.1
TNFAIP3

tumor necrosis factor, alpha-induced protein 3

chr1_+_66258846 0.264 ENST00000341517.4
PDE4B
phosphodiesterase 4B, cAMP-specific
chr10_+_49514698 0.253 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
MAPK8


mitogen-activated protein kinase 8


chrX_-_148713440 0.233 ENST00000536359.1
ENST00000316916.8
TMEM185A

transmembrane protein 185A

chr9_-_132805430 0.229 ENST00000446176.2
ENST00000355681.3
ENST00000420781.1
FNBP1


formin binding protein 1


chr17_+_39868577 0.217 ENST00000329402.3
GAST
gastrin
chr8_-_99837856 0.216 ENST00000518165.1
ENST00000419617.2
STK3

serine/threonine kinase 3

chr11_+_6411636 0.211 ENST00000299397.3
ENST00000356761.2
ENST00000342245.4
SMPD1


sphingomyelin phosphodiesterase 1, acid lysosomal


chr6_-_87804815 0.210 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr3_-_52001448 0.199 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
PCBP4





poly(rC) binding protein 4





chrX_+_16804544 0.194 ENST00000380122.5
ENST00000398155.4
TXLNG

taxilin gamma

chr9_+_133454943 0.187 ENST00000319725.9
FUBP3
far upstream element (FUSE) binding protein 3
chr11_+_6411670 0.184 ENST00000530395.1
ENST00000527275.1
SMPD1

sphingomyelin phosphodiesterase 1, acid lysosomal

chr6_+_138188378 0.179 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr4_+_169418195 0.170 ENST00000261509.6
ENST00000335742.7
PALLD

palladin, cytoskeletal associated protein

chr16_+_2880296 0.167 ENST00000571723.1
ZG16B
zymogen granule protein 16B
chr5_-_132073111 0.166 ENST00000403231.1
KIF3A
kinesin family member 3A
chr4_+_169418255 0.164 ENST00000505667.1
ENST00000511948.1
PALLD

palladin, cytoskeletal associated protein

chr15_+_33010175 0.152 ENST00000300177.4
ENST00000560677.1
ENST00000560830.1
GREM1


gremlin 1, DAN family BMP antagonist


chr19_+_39759154 0.151 ENST00000331982.5
IFNL2
interferon, lambda 2
chr3_-_52719912 0.144 ENST00000420148.1
PBRM1
polybromo 1
chr17_-_29151686 0.142 ENST00000544695.1
CRLF3
cytokine receptor-like factor 3
chr17_-_29151794 0.140 ENST00000324238.6
CRLF3
cytokine receptor-like factor 3
chr9_-_123639304 0.140 ENST00000436309.1
PHF19
PHD finger protein 19
chr17_-_26220366 0.137 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYRM9


RP1-66C13.4
LYR motif containing 9


Uncharacterized protein
chr5_+_125758865 0.136 ENST00000542322.1
ENST00000544396.1
GRAMD3

GRAM domain containing 3

chr16_+_2880157 0.129 ENST00000382280.3
ZG16B
zymogen granule protein 16B
chr6_-_101329191 0.128 ENST00000324723.6
ENST00000369162.2
ENST00000522650.1
ASCC3


activating signal cointegrator 1 complex subunit 3


chr11_-_46867780 0.127 ENST00000529230.1
ENST00000415402.1
ENST00000312055.5
CKAP5


cytoskeleton associated protein 5


chr3_+_52719936 0.123 ENST00000418458.1
ENST00000394799.2
GNL3

guanine nucleotide binding protein-like 3 (nucleolar)

chr3_-_52719810 0.121 ENST00000424867.1
ENST00000394830.3
ENST00000431678.1
ENST00000450271.1
PBRM1



polybromo 1



chr12_+_69201923 0.114 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2





MDM2 oncogene, E3 ubiquitin protein ligase





chr2_+_113321939 0.112 ENST00000458012.2
POLR1B
polymerase (RNA) I polypeptide B, 128kDa
chr3_-_33481835 0.112 ENST00000283629.3
UBP1
upstream binding protein 1 (LBP-1a)
chr1_-_179112173 0.111 ENST00000408940.3
ENST00000504405.1
ABL2

c-abl oncogene 2, non-receptor tyrosine kinase

chr5_+_125758813 0.111 ENST00000285689.3
ENST00000515200.1
GRAMD3

GRAM domain containing 3

chr16_-_30457048 0.110 ENST00000500504.2
ENST00000542752.1
SEPHS2

selenophosphate synthetase 2

chr5_-_81046841 0.109 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
SSBP2


single-stranded DNA binding protein 2


chr2_-_202316169 0.108 ENST00000430254.1
TRAK2
trafficking protein, kinesin binding 2
chr18_-_54305658 0.106 ENST00000586262.1
ENST00000217515.6
TXNL1

thioredoxin-like 1

chr9_+_128510454 0.104 ENST00000491787.3
ENST00000447726.2
PBX3

pre-B-cell leukemia homeobox 3

chr3_-_52719888 0.103 ENST00000458294.1
PBRM1
polybromo 1
chr22_-_30234218 0.103 ENST00000307790.3
ENST00000542393.1
ENST00000397771.2
ASCC2


activating signal cointegrator 1 complex subunit 2


chr4_-_83483094 0.101 ENST00000508701.1
ENST00000454948.3
TMEM150C

transmembrane protein 150C

chr1_-_179112189 0.100 ENST00000512653.1
ENST00000344730.3
ABL2

c-abl oncogene 2, non-receptor tyrosine kinase

chr3_-_127541194 0.098 ENST00000453507.2
MGLL
monoglyceride lipase
chr17_+_8316442 0.096 ENST00000582812.1
NDEL1
nudE neurodevelopment protein 1-like 1
chr2_-_202316260 0.095 ENST00000332624.3
TRAK2
trafficking protein, kinesin binding 2
chr2_+_219081817 0.093 ENST00000315717.5
ENST00000420104.1
ENST00000295685.10
ARPC2


actin related protein 2/3 complex, subunit 2, 34kDa


chr14_+_61995722 0.092 ENST00000556347.1
RP11-47I22.4
RP11-47I22.4
chr3_+_183899770 0.091 ENST00000442686.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr14_-_54421190 0.090 ENST00000417573.1
BMP4
bone morphogenetic protein 4
chr5_+_125759140 0.090 ENST00000543198.1
GRAMD3
GRAM domain containing 3
chr18_-_54318353 0.089 ENST00000590954.1
ENST00000540155.1
TXNL1

thioredoxin-like 1

chr2_-_73460334 0.088 ENST00000258083.2
PRADC1
protease-associated domain containing 1
chr16_+_2880369 0.087 ENST00000572863.1
ZG16B
zymogen granule protein 16B
chr5_-_52405564 0.087 ENST00000510818.2
ENST00000396954.3
ENST00000508922.1
ENST00000361377.4
ENST00000582677.1
ENST00000584946.1
ENST00000450852.3
MOCS2






molybdenum cofactor synthesis 2






chr3_+_32147997 0.087 ENST00000282541.5
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr4_+_128703295 0.087 ENST00000296464.4
ENST00000508549.1
HSPA4L

heat shock 70kDa protein 4-like

chr3_-_127541679 0.086 ENST00000265052.5
MGLL
monoglyceride lipase
chr7_-_148580563 0.085 ENST00000476773.1
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr12_+_49621658 0.085 ENST00000541364.1
TUBA1C
tubulin, alpha 1c
chr2_+_238165734 0.085 ENST00000445534.2
AC112715.2
Uncharacterized protein
chr9_-_123639445 0.084 ENST00000312189.6
PHF19
PHD finger protein 19
chr4_+_140222609 0.084 ENST00000296543.5
ENST00000398947.1
NAA15

N(alpha)-acetyltransferase 15, NatA auxiliary subunit

chr9_-_123639600 0.084 ENST00000373896.3
PHF19
PHD finger protein 19
chr8_+_72755367 0.081 ENST00000537896.1
RP11-383H13.1
Protein LOC100132891; cDNA FLJ53548
chr2_+_219524473 0.080 ENST00000439945.1
ENST00000431802.1
BCS1L

BC1 (ubiquinol-cytochrome c reductase) synthesis-like

chr4_+_3076388 0.078 ENST00000355072.5
HTT
huntingtin
chr3_-_33482002 0.076 ENST00000283628.5
ENST00000456378.1
UBP1

upstream binding protein 1 (LBP-1a)

chr4_-_184241927 0.074 ENST00000323319.5
CLDN22
claudin 22
chr5_-_81046904 0.073 ENST00000515395.1
SSBP2
single-stranded DNA binding protein 2
chr5_-_81046922 0.072 ENST00000514493.1
ENST00000320672.4
SSBP2

single-stranded DNA binding protein 2

chr10_+_94608245 0.071 ENST00000443748.2
ENST00000260762.6
EXOC6

exocyst complex component 6

chr12_+_13044787 0.071 ENST00000534831.1
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr19_+_57050317 0.071 ENST00000301318.3
ENST00000591844.1
ZFP28

ZFP28 zinc finger protein

chr8_-_37594944 0.070 ENST00000330539.1
RP11-863K10.7
Uncharacterized protein
chr20_+_43514320 0.068 ENST00000372839.3
ENST00000428262.1
ENST00000445830.1
YWHAB


tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta


chr20_-_31124186 0.068 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chr22_-_31885514 0.064 ENST00000397525.1
EIF4ENIF1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr12_+_62654155 0.064 ENST00000312635.6
ENST00000393654.3
ENST00000549237.1
USP15


ubiquitin specific peptidase 15


chr11_+_120207787 0.062 ENST00000397843.2
ENST00000356641.3
ARHGEF12

Rho guanine nucleotide exchange factor (GEF) 12

chrX_-_80377162 0.062 ENST00000430960.1
ENST00000447319.1
HMGN5

high mobility group nucleosome binding domain 5

chr11_+_129245796 0.062 ENST00000281437.4
BARX2
BARX homeobox 2
chrX_-_80377118 0.060 ENST00000373250.3
HMGN5
high mobility group nucleosome binding domain 5
chr1_-_179198702 0.060 ENST00000502732.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr6_+_111195973 0.059 ENST00000368885.3
ENST00000368882.3
ENST00000451850.2
ENST00000368877.5
AMD1



adenosylmethionine decarboxylase 1



chr18_-_67872891 0.058 ENST00000454359.1
ENST00000437017.1
RTTN

rotatin

chr1_-_35658736 0.057 ENST00000357214.5
SFPQ
splicing factor proline/glutamine-rich
chr20_-_61847586 0.056 ENST00000370339.3
YTHDF1
YTH domain family, member 1
chr16_-_57481278 0.056 ENST00000567751.1
ENST00000568940.1
ENST00000563341.1
ENST00000565961.1
ENST00000569370.1
ENST00000567518.1
ENST00000565786.1
ENST00000394391.4
CIAPIN1







cytokine induced apoptosis inhibitor 1







chr5_+_72509751 0.054 ENST00000515556.1
ENST00000513379.1
ENST00000427584.2
RP11-60A8.1


RP11-60A8.1


chr10_-_124768300 0.053 ENST00000368886.5
IKZF5
IKAROS family zinc finger 5 (Pegasus)
chr3_+_52828805 0.051 ENST00000416872.2
ENST00000449956.2
ITIH3

inter-alpha-trypsin inhibitor heavy chain 3

chr1_+_145549203 0.050 ENST00000355594.4
ENST00000544626.1
ANKRD35

ankyrin repeat domain 35

chr20_-_39946237 0.049 ENST00000441102.2
ENST00000559234.1
ZHX3

zinc fingers and homeoboxes 3

chr8_+_133787586 0.049 ENST00000395379.1
ENST00000395386.2
ENST00000337920.4
PHF20L1


PHD finger protein 20-like 1


chr9_+_125027127 0.048 ENST00000441707.1
ENST00000373723.5
ENST00000373729.1
MRRF


mitochondrial ribosome recycling factor


chr9_-_99637820 0.045 ENST00000289032.8
ENST00000535338.1
ZNF782

zinc finger protein 782

chr2_-_242842587 0.044 ENST00000404031.1
AC131097.4
Protein LOC285095
chr1_-_201081579 0.043 ENST00000367338.3
ENST00000362061.3
CACNA1S

calcium channel, voltage-dependent, L type, alpha 1S subunit

chr1_+_113263199 0.043 ENST00000361886.3
FAM19A3
family with sequence similarity 19 (chemokine (C-C motif)-like), member A3
chr14_-_21994337 0.042 ENST00000537235.1
ENST00000450879.2
SALL2

spalt-like transcription factor 2

chr19_-_39735646 0.040 ENST00000413851.2
IFNL3
interferon, lambda 3
chr15_+_57668695 0.040 ENST00000281282.5
CGNL1
cingulin-like 1
chr6_-_149867122 0.039 ENST00000253329.2
PPIL4
peptidylprolyl isomerase (cyclophilin)-like 4
chr6_-_116575226 0.038 ENST00000420283.1
TSPYL4
TSPY-like 4
chr18_+_54318616 0.037 ENST00000254442.3
WDR7
WD repeat domain 7
chr9_+_6758109 0.037 ENST00000536108.1
KDM4C
lysine (K)-specific demethylase 4C
chr10_+_28822636 0.036 ENST00000442148.1
ENST00000448193.1
WAC

WW domain containing adaptor with coiled-coil

chr15_-_37392086 0.035 ENST00000561208.1
MEIS2
Meis homeobox 2
chr16_+_50776021 0.033 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
CYLD


cylindromatosis (turban tumor syndrome)


chr5_+_118407053 0.027 ENST00000311085.8
ENST00000539542.1
DMXL1

Dmx-like 1

chr14_+_24600484 0.027 ENST00000267426.5
FITM1
fat storage-inducing transmembrane protein 1
chr10_+_70661014 0.026 ENST00000373585.3
DDX50
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr13_+_20268547 0.026 ENST00000601204.1
AL354808.2
AL354808.2
chr2_-_219524193 0.026 ENST00000450560.1
ENST00000449707.1
ENST00000432460.1
ENST00000411696.2
ZNF142



zinc finger protein 142



chr6_+_150070857 0.026 ENST00000544496.1
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr6_+_150070831 0.025 ENST00000367380.5
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr19_+_36142147 0.025 ENST00000590618.1
COX6B1
cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
chr13_-_48575376 0.024 ENST00000434484.1
SUCLA2
succinate-CoA ligase, ADP-forming, beta subunit
chr9_+_6758024 0.024 ENST00000442236.2
KDM4C
lysine (K)-specific demethylase 4C
chr17_-_72358001 0.023 ENST00000375366.3
BTBD17
BTB (POZ) domain containing 17
chr11_-_19262486 0.023 ENST00000250024.4
E2F8
E2F transcription factor 8
chr4_-_100871506 0.023 ENST00000296417.5
H2AFZ
H2A histone family, member Z
chr4_-_157892498 0.022 ENST00000502773.1
PDGFC
platelet derived growth factor C
chr9_-_140142222 0.022 ENST00000344774.4
ENST00000388932.2
FAM166A

family with sequence similarity 166, member A

chr19_-_38743878 0.021 ENST00000587515.1
PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chrX_-_153095813 0.021 ENST00000544474.1
PDZD4
PDZ domain containing 4
chr18_+_30349623 0.021 ENST00000426194.1
AC012123.1
Uncharacterized protein
chr14_-_21492113 0.020 ENST00000554094.1
NDRG2
NDRG family member 2
chr2_-_61765732 0.020 ENST00000443240.1
ENST00000436018.1
XPO1

exportin 1 (CRM1 homolog, yeast)

chr6_-_114664180 0.020 ENST00000312719.5
HS3ST5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr9_-_73477826 0.020 ENST00000396285.1
ENST00000396292.4
ENST00000396280.5
ENST00000358082.3
ENST00000408909.2
ENST00000377097.3
TRPM3





transient receptor potential cation channel, subfamily M, member 3





chr16_+_2880254 0.020 ENST00000570670.1
ZG16B
zymogen granule protein 16B
chr8_-_20161466 0.019 ENST00000381569.1
LZTS1
leucine zipper, putative tumor suppressor 1
chr2_+_173724771 0.019 ENST00000538974.1
ENST00000540783.1
RAPGEF4

Rap guanine nucleotide exchange factor (GEF) 4

chr4_-_157892055 0.018 ENST00000422544.2
PDGFC
platelet derived growth factor C
chr2_+_128848740 0.018 ENST00000375990.3
UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr10_+_51565188 0.018 ENST00000430396.2
ENST00000374087.4
ENST00000414907.2
NCOA4


nuclear receptor coactivator 4


chr6_+_31674639 0.017 ENST00000556581.1
ENST00000375832.4
ENST00000503322.1
LY6G6F

MEGT1
lymphocyte antigen 6 complex, locus G6F

HCG43720, isoform CRA_a; Lymphocyte antigen 6 complex locus protein G6f; Megakaryocyte-enhanced gene transcript 1 protein; Uncharacterized protein
chr5_-_139283982 0.017 ENST00000340391.3
NRG2
neuregulin 2
chr1_+_109756523 0.017 ENST00000234677.2
ENST00000369923.4
SARS

seryl-tRNA synthetase

chr15_+_96904487 0.016 ENST00000600790.1
AC087477.1
Uncharacterized protein
chrX_-_71792477 0.016 ENST00000421523.1
ENST00000415409.1
ENST00000373559.4
ENST00000373556.3
ENST00000373560.2
ENST00000373583.1
ENST00000429103.2
ENST00000373571.1
ENST00000373554.1
HDAC8








histone deacetylase 8








chr9_+_98637954 0.016 ENST00000288985.7
ERCC6L2
excision repair cross-complementing rodent repair deficiency, complementation group 6-like 2
chr1_+_161736072 0.015 ENST00000367942.3
ATF6
activating transcription factor 6
chr9_+_131873842 0.014 ENST00000417728.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr11_-_119247004 0.013 ENST00000531070.1
USP2
ubiquitin specific peptidase 2
chr6_+_108881012 0.013 ENST00000343882.6
FOXO3
forkhead box O3
chr11_-_59383617 0.013 ENST00000263847.1
OSBP
oxysterol binding protein
chrX_-_77225135 0.012 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr16_-_1275257 0.012 ENST00000234798.4
TPSG1
tryptase gamma 1
chr4_+_166300084 0.012 ENST00000402744.4
CPE
carboxypeptidase E
chr3_+_185080908 0.011 ENST00000265026.3
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr8_+_72755796 0.011 ENST00000524152.1
RP11-383H13.1
Protein LOC100132891; cDNA FLJ53548
chr12_+_62654119 0.011 ENST00000353364.3
ENST00000549523.1
ENST00000280377.5
USP15


ubiquitin specific peptidase 15


chr5_+_118406796 0.009 ENST00000503802.1
DMXL1
Dmx-like 1
chr2_+_128848881 0.008 ENST00000259253.6
UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr4_-_46391805 0.008 ENST00000540012.1
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr2_+_64681103 0.008 ENST00000464281.1
LGALSL
lectin, galactoside-binding-like
chr9_+_87285539 0.008 ENST00000359847.3
NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr16_+_57481382 0.008 ENST00000564655.1
ENST00000567072.1
ENST00000567933.1
ENST00000563166.1
COQ9



coenzyme Q9



chr19_-_6424783 0.007 ENST00000398148.3
KHSRP
KH-type splicing regulatory protein
chr6_+_17600576 0.007 ENST00000259963.3
FAM8A1
family with sequence similarity 8, member A1
chr11_-_71810258 0.007 ENST00000544594.1
LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr3_+_186692745 0.007 ENST00000438590.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr18_+_54318566 0.006 ENST00000589935.1
ENST00000357574.3
WDR7

WD repeat domain 7

chr17_-_3499125 0.006 ENST00000399759.3
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr3_+_23244780 0.006 ENST00000396703.1
UBE2E2
ubiquitin-conjugating enzyme E2E 2
chr4_-_157892167 0.006 ENST00000541126.1
PDGFC
platelet derived growth factor C
chr9_-_140142181 0.006 ENST00000484720.1
FAM166A
family with sequence similarity 166, member A
chr5_+_78985673 0.006 ENST00000446378.2
CMYA5
cardiomyopathy associated 5
chr8_+_57124245 0.006 ENST00000521831.1
ENST00000355315.3
ENST00000303759.3
ENST00000517636.1
ENST00000517933.1
ENST00000518801.1
ENST00000523975.1
ENST00000396723.5
ENST00000523061.1
ENST00000521524.1
CHCHD7









coiled-coil-helix-coiled-coil-helix domain containing 7









chr2_-_190446738 0.005 ENST00000427419.1
ENST00000455320.1
SLC40A1

solute carrier family 40 (iron-regulated transporter), member 1

chr2_+_64681219 0.005 ENST00000238875.5
LGALSL
lectin, galactoside-binding-like
chr2_-_74780176 0.004 ENST00000409549.1
LOXL3
lysyl oxidase-like 3
chr21_-_26797019 0.003 ENST00000440205.1
LINC00158
long intergenic non-protein coding RNA 158
chr11_-_64013288 0.003 ENST00000542235.1
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr15_+_68346501 0.002 ENST00000249636.6
PIAS1
protein inhibitor of activated STAT, 1
chr17_-_42452063 0.001 ENST00000588098.1
ITGA2B
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr21_-_34185989 0.001 ENST00000487113.1
ENST00000382373.4
C21orf62

chromosome 21 open reading frame 62

chr21_-_32931290 0.001 ENST00000286827.3
TIAM1
T-cell lymphoma invasion and metastasis 1
chr2_-_61765315 0.001 ENST00000406957.1
ENST00000401558.2
XPO1

exportin 1 (CRM1 homolog, yeast)


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0070429 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.1 0.3 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.1 0.2 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291)
0.1 0.2 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.0 0.4 GO:0023021 termination of signal transduction(GO:0023021)
0.0 0.1 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0 0.6 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.1 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.1 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.0 0.1 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.0 0.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.1 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0 0.3 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.1 GO:0048389 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) deltoid tuberosity development(GO:0035993) intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) pattern specification involved in mesonephros development(GO:0061227) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.2 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.0 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.0 GO:1903979 negative regulation of microglial cell activation(GO:1903979)
0.0 0.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.4 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.5 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.1 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.1 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0070012 oligopeptidase activity(GO:0070012)
0.0 0.1 GO:0019808 polyamine binding(GO:0019808)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.0 0.7 PID_CD40_PATHWAY CD40/CD40L signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 0.3 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions